Package: InterSIM
Type: Package
Title: Simulation of Inter-Related Genomic Datasets
Version: 2.3.0
Date: 2025-01-10
Authors@R: c(person(given = "Prabhakar",
                      family = "Chalise",
                      role = c("aut", "cre"),
                      email = "pchalise@kumc.edu"),
               person(given = "Rama",
                      family = "Raghavan",
                      role = "aut"),
               person(given = "Brooke",
                      family = "Fridley",
                      role = "aut"))
Author: Prabhakar Chalise [aut, cre],
  Rama Raghavan [aut],
  Brooke Fridley [aut]
Maintainer: Prabhakar Chalise <pchalise@kumc.edu>
Description: Generates three inter-related genomic datasets: methylation, gene expression and protein expression having user specified cluster patterns. The simulation utilizes the realistic inter- and intra- relationships from real DNA methylation, mRNA expression and protein expression data from the TCGA ovarian cancer study, Chalise (2016) <doi:10.1016/j.cmpb.2016.02.011>.  
License: GPL
Depends: R (>= 3.5.0), MASS, NMF, tools
NeedsCompilation: no
Packaged: 2025-01-10 17:38:30 UTC; 
Repository: CRAN
Date/Publication: 2025-01-10 23:00:06 UTC
RoxygenNote: 6.0.1
Built: R 4.6.0; ; 2026-04-25 17:16:29 UTC; unix
