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@article{risso2011gc,
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  author={Risso, Davide and Schwartz, Katja and Sherlock, Gavin and Dudoit, Sandrine},
  journal={BMC Bioinformatics},
  volume={12},
  number={1},
  pages={480},
  year={2011},
  publisher={BioMed Central}
}

@article{hansen2012removing,
  title={Removing technical variability in {RNA}-seq data using conditional quantile normalization},
  author={Hansen, Kasper D and Irizarry, Rafael A and Wu, Zhijin},
  journal={Biostatistics},
  volume={13},
  number={2},
  pages={204--216},
  year={2012},
  publisher={Oxford University Press}
}

@article{bullard2010evaluation,
  title={Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments},
  author={Bullard, James H and Purdom, Elizabeth and Hansen, Kasper D and Dudoit, Sandrine},
  journal={BMC Bioinformatics},
  volume={11},
  number={1},
  pages={94},
  year={2010},
  publisher={BioMed Central}
}

@article{trapnell2010transcript,
  title={Transcript assembly and quantification by {RNA}-Seq reveals unannotated transcripts and isoform switching during cell differentiation},
  author={Trapnell, Cole and Williams, Brian A and Pertea, Geo and Mortazavi, Ali and Kwan, Gordon and Van Baren, Marijke J and Salzberg, Steven L and Wold, Barbara J and Pachter, Lior},
  journal={Nature Biotechnology},
  volume={28},
  number={5},
  pages={511},
  year={2010},
  publisher={Nature Publishing Group}
}


@article{soneson2013comparison,
  title={A comparison of methods for differential expression analysis of {RNA}-seq data},
  author={Soneson, Charlotte and Delorenzi, Mauro},
  journal={BMC Bioinformatics},
  volume={14},
  number={1},
  pages={91},
  year={2013},
  publisher={BioMed Central}
}

@article{li2017comparison,
  title={A comparison of per sample global scaling and per gene normalization methods for differential expression analysis of {RNA}-seq data},
  author={Li, Xiaohong and Brock, Guy N and Rouchka, Eric C and Cooper, Nigel GF and Wu, Dongfeng and O’Toole, Timothy E and Gill, Ryan S and Eteleeb, Abdallah M and O’Brien, Liz and Rai, Shesh N},
  journal={PloS One},
  volume={12},
  number={5},
  pages={e0176185},
  year={2017},
  publisher={Public Library of Science}
}

@article{law2014voom,
  title={{V}oom: {P}recision weights unlock linear model analysis tools for {RNA}-seq read counts},
  author={Law, Charity W and Chen, Yunshun and Shi, Wei and Smyth, Gordon K},
  journal={Genome Biology},
  volume={15},
  number={2},
  pages={R29},
  year={2014},
  publisher={BioMed Central}
}

@article{marioni2008rna,
  title={RNA-seq: {A}n assessment of technical reproducibility and comparison with gene expression arrays},
  author={Marioni, John C and Mason, Christopher E and Mane, Shrikant M and Stephens, Matthew and Gilad, Yoav},
  journal={Genome Research},
  volume={18},
  number={9},
  pages={1509--1517},
  year={2008},
  publisher={Cold Spring Harbor Lab}
}

@article{robinson2010edger,
  title={edgeR: {A} {B}ioconductor package for differential expression analysis of digital gene expression data},
  author={Robinson, Mark D and McCarthy, Davis J and Smyth, Gordon K},
  journal={Bioinformatics},
  volume={26},
  number={1},
  pages={139--140},
  year={2010},
  publisher={Oxford University Press}
}

@article{anders2010differential,
  title={Differential expression analysis for sequence count data},
  author={Anders, Simon and Huber, Wolfgang},
  journal={Genome Biology},
  volume={11},
  number={10},
  pages={R106},
  year={2010},
  publisher={BioMed Central}
}


@article {Reddy026062,
	author = {Reddy, Rahul},
	title = {A Comparison of Methods: {N}ormalizing High-Throughput {RNA} Sequencing Data},
	year = {2015},
	doi = {10.1101/026062},
	URL = {https://www.biorxiv.org/content/early/2015/09/03/026062},
	eprint = {https://www.biorxiv.org/content/early/2015/09/03/026062.full.pdf},
	journal = {bioRxiv}
}

@Manual{MEAL,
    title = {MEAL: {P}erform methylation analysis},
    author = {Carlos Ruiz-Arenas and Carles Hernandez-Ferrer and Juan R. Gonz{\'a}lez},
    year = {2017},
    note = {R package version 1.6.0},
  }
  
@article{ruiz2017redundancy,
  title={Redundancy analysis allows improved detection of methylation changes in large genomic regions},
  author={Ruiz-Arenas, Carlos and Gonz{\'a}lez, Juan R},
  journal={BMC Bioinformatics},
  volume={18},
  number={1},
  pages={553},
  year={2017},
  publisher={BioMed Central}
}  
  
@article{frazee2011recount,
  title={ReCount: {A} multi-experiment resource of analysis-ready {RNA}-seq gene count datasets},
  author={Frazee, Alyssa C and Langmead, Ben and Leek, Jeffrey T},
  journal={BMC Bioinformatics},
  volume={12},
  number={1},
  pages={449},
  year={2011},
  publisher={BioMed Central}
}  

@article{pickrell2010understanding,
  title={Understanding mechanisms underlying human gene expression variation with {RNA} sequencing},
  author={Pickrell, Joseph K and Marioni, John C and Pai, Athma A and Degner, Jacob F and Engelhardt, Barbara E and Nkadori, Everlyne and Veyrieras, Jean-Baptiste and Stephens, Matthew and Gilad, Yoav and Pritchard, Jonathan K},
  journal={Nature},
  volume={464},
  number={7289},
  pages={768},
  year={2010},
  publisher={Nature Publishing Group}
}


@article{bourgon2010independent,
  title={Independent filtering increases detection power for high-throughput experiments},
  author={Bourgon, Richard and Gentleman, Robert and Huber, Wolfgang},
  journal={Proceedings of the National Academy of Sciences},
  volume={107},
  number={21},
  pages={9546--9551},
  year={2010},
  publisher={National Acad Sciences}
}

@article{hansen2011increased,
  title={Increased methylation variation in epigenetic domains across cancer types},
  author={Hansen, Kasper Daniel and Timp, Winston and Bravo, H{\'e}ctor Corrada and Sabunciyan, Sarven and Langmead, Benjamin and McDonald, Oliver G and Wen, Bo and Wu, Hao and Liu, Yun and Diep, Dinh and others},
  journal={Nature Genetics},
  volume={43},
  number={8},
  pages={768},
  year={2011},
  publisher={Nature Publishing Group}
}

###chp9
@article{vanderweele2016mediation,
  title={Mediation analysis: {A} practitioner's guide},
  author={VanderWeele, Tyler J},
  journal={Annual Review of Public Health},
  volume={37},
  pages={17--32},
  year={2016},
  publisher={Annual Reviews}
}

@article{tingley2014mediation,
  title={Mediation: {R} package for causal mediation analysis},
  author={Tingley, Dustin and Yamamoto, Teppei and Hirose,    Kentaro and Keele, Luke and Imai, Kosuke},
 journal={Journal of Statistical Software},
  volume={59},
  pages={1},
  year={2014},
}

@article{huang2014joint,
  title={Joint analysis of {SNP} and gene expression data in genetic association studies of complex diseases},
  author={Huang, Yen-Tsung and VanderWeele, Tyler J and Lin, Xihong},
  journal={The Annals of Applied Statistics},
  volume={8},
  number={1},
  pages={352},
  year={2014},
  publisher={NIH Public Access}
}

@article{wu2018mediation,
  title={Mediation analysis of alcohol consumption, {DNA} methylation, and epithelial ovarian cancer},
  author={Wu, Dongyan and Yang, Haitao and Winham, Stacey J and Natanzon, Yanina and Koestler, Devin C and Luo, Tiane and Fridley, Brooke L and Goode, Ellen L and Zhang, Yanbo and Cui, Yuehua},
  journal={Journal of Human Genetics},
  pages={1},
  year={2018},
  publisher={Nature Publishing Group}
}

@article{richmond2016challenges,
  title={Challenges and novel approaches for investigating molecular mediation},
  author={Richmond, RC and Hemani, G and Tilling, K and Davey Smith, G and Relton, CL},
  journal={Human Molecular Genetics},
  volume={25},
  number={R2},
  pages={R149--R156},
  year={2016},
  publisher={Oxford University Press}
}

@article{baron1986moderator,
  title={The moderator--mediator variable distinction in social psychological research: {C}onceptual, strategic, and statistical considerations.},
  author={Baron, Reuben M and Kenny, David A},
  journal={Journal of Personality and Social Psychology},
  volume={51},
  number={6},
  pages={1173},
  year={1986},
  publisher={American Psychological Association}
}

@article{shrout2002mediation,
  title={Mediation in experimental and nonexperimental studies: {N}ew procedures and recommendations.},
  author={Shrout, Patrick E and Bolger, Niall},
  journal={Psychological Methods},
  volume={7},
  number={4},
  pages={422},
  year={2002},
  publisher={US: American Psychological Association}
}

@article{jacobs2012detectable,
  title={Detectable clonal mosaicism and its relationship to aging and cancer},
  author={Jacobs, Kevin B and Yeager, Meredith and Zhou, Weiyin and Wacholder, Sholom and Wang, Zhaoming and Rodriguez-Santiago, Benjamin and Hutchinson, Amy and Deng, Xiang and Liu, Chenwei and Horner, Marie-Josephe and others},
  journal={Nature Genetics},
  volume={44},
  number={6},
  pages={651},
  year={2012},
  publisher={Nature Publishing Group}
}

@article{preacher2008asymptotic,
  title={Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models},
  author={Preacher, Kristopher J and Hayes, Andrew F},
  journal={Behavior Research Methods},
  volume={40},
  number={3},
  pages={879--891},
  year={2008},
  publisher={Springer}
}

@article{ritchie2015methods,
  title={Methods of integrating data to uncover genotype--phenotype interactions},
  author={Ritchie, Marylyn D and Holzinger, Emily R and Li, Ruowang and Pendergrass, Sarah A and Kim, Dokyoon},
  journal={Nature Reviews Genetics},
  volume={16},
  number={2},
  pages={85},
  year={2015},
  publisher={Nature Publishing Group}
}

@article{millstein2016cit,
  title={CIT: {H}ypothesis testing software for mediation analysis in genomic applications},
  author={Millstein, Joshua and Chen, Gary K and Breton, Carrie V},
  journal={Bioinformatics},
  volume={32},
  number={15},
  pages={2364--2365},
  year={2016},
  publisher={Oxford University Press}
}


@article{millstein2009disentangling,
  title={Disentangling molecular relationships with a causal inference test},
  author={Millstein, Joshua and Zhang, Bin and Zhu, Jun and Schadt, Eric E},
  journal={BMC Genetics},
  volume={10},
  number={1},
  pages={23},
  year={2009},
  publisher={BioMed Central}
}


@article{encode2004encode,
  title={The ENCODE (ENCyclopedia of {DNA} elements) project},
  author={ENCODE Project Consortium and others},
  journal={Science},
  volume={306},
  number={5696},
  pages={636--640},
  year={2004},
  publisher={American Association for the Advancement of Science}
}


@article{bernstein2010nih,
  title={The NIH roadmap epigenomics mapping consortium},
  author={Bernstein, Bradley E and Stamatoyannopoulos, John A and Costello, Joseph F and Ren, Bing and Milosavljevic, Aleksandar and Meissner, Alexander and Kellis, Manolis and Marra, Marco A and Beaudet, Arthur L and Ecker, Joseph R and others},
  journal={Nature Biotechnology},
  volume={28},
  number={10},
  pages={1045},
  year={2010},
  publisher={Nature Publishing Group}
}


@article{witten2009penalized,
  title={A penalized matrix decomposition, with applications to sparse principal components and canonical correlation analysis},
  author={Witten, Daniela M and Tibshirani, Robert and Hastie, Trevor},
  journal={Biostatistics},
  volume={10},
  number={3},
  pages={515--534},
  year={2009},
  publisher={Oxford University Press}
}

@article{meng2016dimension,
  title={Dimension reduction techniques for the integrative analysis of multi-omics data},
  author={Meng, Chen and Zeleznik, Oana A and Thallinger, Gerhard G and Kuster, Bernhard and Gholami, Amin M and Culhane, Aed{\'\i}n C},
  journal={Briefings in Bioinformatics},
  volume={17},
  number={4},
  pages={628--641},
  year={2016},
  publisher={Oxford University Press}
}


@article{witten2009extensions,
  title={Extensions of sparse canonical correlation analysis with applications to genomic data},
  author={Witten, Daniela M and Tibshirani, Robert J},
  journal={Statistical Applications in Genetics and Molecular Biology},
  volume={8},
  number={1},
  pages={1--27},
  year={2009},
  publisher={De Gruyter}
}

@book{ullman2012structural,
  title={Structural equation modeling},
  author={Ullman, Jodie B and Bentler, Peter M},
  journal={Handbook of Psychology, Second Edition},
  volume={2},
  year={2012},
  publisher={Wiley Online Library}
}

@article{tenenhaus2011regularized,
  title={Regularized generalized canonical correlation analysis},
  author={Tenenhaus, Arthur and Tenenhaus, Michel},
  journal={Psychometrika},
  volume={76},
  number={2},
  pages={257},
  year={2011},
  publisher={Springer}
}

@article{tenenhaus2017regularized,
  title={Regularized generalized canonical correlation analysis: {A} framework for sequential multiblock component methods},
  author={Tenenhaus, Michel and Tenenhaus, Arthur and Groenen, Patrick JF},
  journal={Psychometrika},
  volume={82},
  number={3},
  pages={737--777},
  year={2017},
  publisher={Springer}
}

@article{tenenhaus2014variable,
  title={Variable selection for generalized canonical correlation analysis},
  author={Tenenhaus, Arthur and Philippe, Cathy and Guillemot, Vincent and Le Cao, Kim-Anh and Grill, Jacques and Frouin, Vincent},
  journal={Biostatistics},
  volume={15},
  number={3},
  pages={569--583},
  year={2014},
  publisher={Oxford University Press}
}

@article{meng2014multivariate,
  title={A multivariate approach to the integration of multi-omics datasets},
  author={Meng, Chen and Kuster, Bernhard and Culhane, Aed{\'\i}n C and Gholami, Amin Moghaddas},
  journal={BMC Bioinformatics},
  volume={15},
  number={1},
  pages={162},
  year={2014},
  publisher={BioMed Central}
}


@article{steenaard2015tobacco,
  title={Tobacco smoking is associated with methylation of genes related to coronary artery disease},
  author={Steenaard, Rebecca V and Ligthart, Symen and Stolk, Lisette and Peters, Marjolein J and van Meurs, Joyce B and Uitterlinden, Andre G and Hofman, Albert and Franco, Oscar H and Dehghan, Abbas},
  journal={Clinical Epigenetics},
  volume={7},
  number={1},
  pages={54},
  year={2015},
  publisher={BioMed Central}
}

# chapter exposomic

@article{hindorff2011genetic,
  title={Genetic architecture of cancer and other complex diseases: {L}essons learned and future directions},
  author={Hindorff, Lucia A and Gillanders, Elizabeth M and Manolio, Teri A},
  journal={Carcinogenesis},
  volume={32},
  number={7},
  pages={945--954},
  year={2011},
  publisher={Oxford University Press}
}

@article{ehret2011genetic,
  title={Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk},
  author={Ehret, Georg B and Munroe, Patricia B and Rice, Kenneth M and Bochud, Murielle and Johnson, Andrew D and Chasman, Daniel I and Smith, Albert V and Tobin, Martin D and Verwoert, Germaine C and Hwang, Shih-Jen and others},
  journal={Nature},
  volume={478},
  number={7367},
  pages={103},
  year={2011},
  publisher={Nature Publishing Group}
}


@article{international2011imputation,
  title={Imputation of sequence variants for identification of genetic risks for {P}arkinson's disease: {A} meta-analysis of genome-wide association studies},
  author={International Parkinson Disease Genomics Consortium and others},
  journal={The Lancet},
  volume={377},
  number={9766},
  pages={641--649},
  year={2011},
  publisher={Elsevier}
}


@article{feigin2016global,
  title={Global burden of stroke and risk factors in 188 countries, during 1990--2013: {A} systematic analysis for the Global Burden of Disease Study 2013},
  author={Feigin, Valery L and Roth, Gregory A and Naghavi, Mohsen and Parmar, Priya and Krishnamurthi, Rita and Chugh, Sumeet and Mensah, George A and Norrving, Bo and Shiue, Ivy and Ng, Marie and others},
  journal={The Lancet Neurology},
  volume={15},
  number={9},
  pages={913--924},
  year={2016},
  publisher={Elsevier}
}

@misc{wild2005complementing,
  title={Complementing the genome with an “exposome”: {T}he outstanding challenge of environmental exposure measurement in molecular epidemiology},
  author={Wild, Christopher Paul},
  year={2005},
  publisher={AACR}
}

@article{wild2012exposome,
  title={The exposome: {F}rom concept to utility},
  author={Wild, Christopher Paul},
  journal={International Journal of Epidemiology},
  volume={41},
  number={1},
  pages={24--32},
  year={2012},
  publisher={Oxford University Press}
}

@article{rappaport2010environment,
  title={Environment and disease risks},
  author={Rappaport, Stephen M and Smith, Martyn T},
  journal={Science},
  volume={330},
  number={6003},
  pages={460--461},
  year={2010},
  publisher={American Association for the Advancement of Science}
}


@misc{svingen2015risk,
  title={The risk of chemical cocktail effects and how to deal with the issue},
  author={Svingen, Terje and Vinggaard, Anne Marie},
  journal={Journal of Epidemiology and Community Health},
  volume={70},
  number={4},
  pages={322-323},
  year={2015},
  publisher={BMJ Publishing Group Ltd}
}

@article{vrijheid2014human,
  title={The human early-life exposome (HELIX): {P}roject rationale and design},
  author={Vrijheid, Martine and Slama, R{\'e}my and Robinson, Oliver and Chatzi, Leda and Coen, Muireann and Van den Hazel, Peter and Thomsen, Cathrine and Wright, John and Athersuch, Toby J and Avellana, Narcis and others},
  journal={Environmental Health Perspectives},
  volume={122},
  number={6},
  pages={535},
  year={2014},
  publisher={National Institute of Environmental Health Science}
}



# news after revision

@article{lettre2007genetic,
  title={Genetic model testing and statistical power in population-based association studies of quantitative traits},
  author={Lettre, Guillaume and Lange, Christoph and Hirschhorn, Joel N},
  journal={Genetic Epidemiology},
  volume={31},
  number={4},
  pages={358--362},
  year={2007},
  publisher={Wiley Online Library}
}

@article{balding2006tutorial,
  title={A tutorial on statistical methods for population association studies},
  author={Balding, David J},
  journal={Nature Reviews Genetics},
  volume={7},
  number={10},
  pages={781},
  year={2006},
  publisher={Nature Publishing Group}
}


@article{gonzalez2008maximizing,
  title={Maximizing association statistics over genetic models},
  author={Gonz{\'a}lez, Juan R and Carrasco, Josep L and Dudbridge, Frank and Armengol, Llu{\'\i}s and Estivill, Xavier and Moreno, Victor},
  journal={Genetic Epidemiology},
  volume={32},
  number={3},
  pages={246--254},
  year={2008},
  publisher={Wiley Online Library}
}

@article{joo2010efficiency,
  title={Efficiency robust statistics for genetic linkage and association studies under genetic model uncertainty},
  author={Joo, Jungnam and Kwak, Minjung and Chen, Zehua and Zheng, Gang},
  journal={Statistics in Medicine},
  volume={29},
  number={1},
  pages={158--180},
  year={2010},
  publisher={Wiley Online Library}
}

@article{macarthur2016new,
  title={The new {NHGRI-EBI} Catalog of published genome-wide association studies ({GWAS} Catalog)},
  author={MacArthur, Jacqueline and Bowler, Emily and Cerezo, Maria and Gil, Laurent and Hall, Peggy and Hastings, Emma and Junkins, Heather and McMahon, Aoife and Milano, Annalisa and Morales, Joannella and others},
  journal={Nucleic Acids Research},
  volume={45},
  number={D1},
  pages={D896--D901},
  year={2016},
  publisher={Oxford University Press}
}

@article{price2010new,
  title={New approaches to population stratification in genome-wide association studies},
  author={Price, Alkes L and Zaitlen, Noah A and Reich, David and Patterson, Nick},
  journal={Nature Reviews Genetics},
  volume={11},
  number={7},
  pages={459},
  year={2010},
  publisher={Nature Publishing Group}
}

@article{price2006principal,
  title={Principal components analysis corrects for stratification in genome-wide association studies},
  author={Price, Alkes L and Patterson, Nick J and Plenge, Robert M and Weinblatt, Michael E and Shadick, Nancy A and Reich, David},
  journal={Nature Genetics},
  volume={38},
  number={8},
  pages={904},
  year={2006},
  publisher={Nature Publishing Group}
}

@article{purcell2007plink,
  title={PLINK: {A} tool set for whole-genome association and population-based linkage analyses},
  author={Purcell, Shaun and Neale, Benjamin and Todd-Brown, Kathe and Thomas, Lori and Ferreira, Manuel AR and Bender, David and Maller, Julian and Sklar, Pamela and De Bakker, Paul IW and Daly, Mark J and others},
  journal={The American Journal of Human Genetics},
  volume={81},
  number={3},
  pages={559--575},
  year={2007},
  publisher={Elsevier}
}

@article{lawrence2013software,
  title={Software for computing and annotating genomic ranges},
  author={Lawrence, Michael and Huber, Wolfgang and Pages, Herv{\'e} and Aboyoun, Patrick and Carlson, Marc and Gentleman, Robert and Morgan, Martin T and Carey, Vincent J},
  journal={PLoS Computational Biology},
  volume={9},
  number={8},
  pages={e1003118},
  year={2013},
  publisher={Public Library of Science}
}

@article{gonzalez2007snpassoc,
  title={{SNP}assoc: {A}n {R} package to perform whole genome association studies},
  author={Gonz{\'a}lez, Juan R and Armengol, Llu{\'\i}s and Sol{\'e}, Xavier and Guin{\'o}, Elisabet and Mercader, Josep M and Estivill, Xavier and Moreno, V{\'\i}ctor},
  journal={Bioinformatics},
  volume={23},
  number={5},
  pages={654--655},
  year={2007},
  publisher={Oxford University Press}
}


@article{asherson2007confirmation,
  title={Confirmation that a specific haplotype of the dopamine transporter gene is associated with combined-type {ADHD}},
  author={Asherson, Philip and Brookes, Keeley and Franke, Barbara and Chen, Wai and Gill, Michael and Ebstein, Richard P and Buitelaar, Jan and Banaschewski, Tobias and Sonuga-Barke, Edmund and Eisenberg, Jacques and others},
  journal={American Journal of Psychiatry},
  volume={164},
  number={4},
  pages={674--677},
  year={2007},
  publisher={Am Psychiatric Assoc}
}

@article{hivert2011updated,
  title={Updated genetic score based on 34 confirmed type 2 diabetes Loci is associated with diabetes incidence and regression to normoglycemia in the diabetes prevention program},
  author={Hivert, Marie-France and Jablonski, Kathleen A and Perreault, Leigh and Saxena, Richa and McAteer, Jarred B and Franks, Paul W and Hamman, Richard F and Kahn, Steven E and Haffner, Steven and Meigs, James B and others},
  journal={Diabetes},
  volume={60},
  number={4},
  pages={1340--1348},
  year={2011},
  publisher={Am Diabetes Assoc}
}

@article{international2003international,
  title={The international HapMap project},
  author={International HapMap Consortium and others},
  journal={Nature},
  volume={426},
  number={6968},
  pages={789},
  year={2003},
  publisher={Nature Publishing Group}
}

@article{zhao2003haplotype,
  title={Haplotype analysis in population genetics and association studies},
  author={Zhao, Hongyu and Pfeiffer, Ruth and Gail, Mitchell H},
  journal={Pharmacogenomics},
  volume={4},
  number={2},
  pages={171--178},
  year={2003},
  publisher={Future Medicine}
}

@article{nair2006sequence,
  title={Sequence and haplotype analysis supports {HLA-C} as the psoriasis susceptibility 1 gene},
  author={Nair, Rajan P and Stuart, Philip E and Nistor, Ioana and Hiremagalore, Ravi and Chia, Nicholas VC and Jenisch, Stefan and Weichenthal, Michael and Abecasis, Gon{\c{c}}alo R and Lim, Henry W and Christophers, Enno and others},
  journal={The American Journal of Human Genetics},
  volume={78},
  number={5},
  pages={827--851},
  year={2006},
  publisher={Elsevier}
}

@article{zill2004single,
  title={Single nucleotide polymorphism and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene in suicide victims},
  author={Zill, Peter and B{\"u}ttner, Andreas and Eisenmenger, Wolfgang and M{\"o}ller, Hans-J{\"u}rgen and Bondy, Brigitta and Ackenheil, Manfred},
  journal={Biological Psychiatry},
  volume={56},
  number={8},
  pages={581--586},
  year={2004},
  publisher={Elsevier}
}

@article{mill2004haplotype,
  title={Haplotype analysis of {SNAP}-25 suggests a role in the aetiology of ADHD},
  author={Mill, J and Richards, S and Knight, Jo and Curran, S and Taylor, Eleanor and Asherson, Philip},
  journal={Molecular Psychiatry},
  volume={9},
  number={8},
  pages={801},
  year={2004},
  publisher={Nature Publishing Group}
}



@article{gonzalez2012fto,
  title={{FTO} risk haplotype among early onset and severe obesity cases in a population of western Spain},
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