FN Thomson Reuters Web of Science™ VR 1.0 PT J AU MOUL, J AF MOUL, J TI LONG-TERM RESULTS WITH VACUUM CONSTRICTION DEVICE - COMMENT SO JOURNAL OF UROLOGY LA English DT Editorial Material RP MOUL, J (reprint author), WALTER REED ARMY MED CTR,WASHINGTON,DC 20307, USA. NR 0 TC 2 Z9 2 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0022-5347 J9 J UROLOGY JI J. Urol. PD FEB PY 1993 VL 149 IS 2 BP 294 EP 294 PG 1 WC Urology & Nephrology SC Urology & Nephrology GA KK264 UT WOS:A1993KK26400017 ER PT J AU BURGESS, LPA AF BURGESS, LPA TI LARYNGEAL RECONSTRUCTION FOLLOWING VERTICAL PARTIAL LARYNGECTOMY SO LARYNGOSCOPE LA English DT Article ID GLOTTIC RECONSTRUCTION; SUBTOTAL LARYNGECTOMY; FLAP RECONSTRUCTION; EPIGLOTTIC LARYNGOPLASTY; ANTERIOR COMMISSURE; VOCAL CORD; HEMILARYNGECTOMY; CANCER; GRAFTS; MANAGEMENT AB Laryngeal reconstruction following vertical partial laryngectomy (VPL) with arytenoidectomy was studied in 30 dogs. Variations of a superiorly based thyroid cartilage flap (TCF) were used for reconstruction. In addition, sternohyoid muscle reconstruction and endolaryngeal muscle coverage were studied. Larynges were recovered after a 6-month period in 28 surviving dogs and were analyzed by endoscopic photographs and axial whole-organ sections. Endoscopic assessment (n = 18) demonstrated good results for arytenoid replacement (100%), pseudocord position (94%), pseudocord development (94%), and airway patency (100%). Arytenoid replacement was judged as completely (78%) or partially (22%) replaced. This was accomplished by a pseudocord extending to the cricoid in the horizontal plane. Pseudocord position was judged as normal (83%) or paramedian (11%), with the remainder lateralized (6%). Pseudocord development was judged as complete (72%) or partial (22%), with the remainder poor (6%). Reviewing both endoscopic photographs and gross sections (n = 28), airways were all normal without laryngeal or tracheal stenosis. Histologic assessment (n = 24) also demonstrated good results for arytenoid replacement (79%), pseudocord position (87%), and TCF survival in the glottic plane (79%). Arytenoid replacement was judged as complete (62%) or partial (17%), with the remainder poor (21%). Pseudocord position was judged as normal (50%) or paramedian (37%), with the remainder lateralized (13%). TCF survival was judged as total (63%) or partial (16%). Although not present in the glottic plane in the remaining cases (21%), a portion of the TCF was always present in the supraglottic region. The TCF was largely replaced by bone in the region of the pseudocord, and was covered by nonkeratinizing stratified squamous epithelium and a thick fibrous layer. Breakdown over the TCF was infrequent, with a small focus of granulation tissue over cartilage present in 1 (4%) of 24 cases. Clinically insignificant granulation tissue was present in a total of 6 (25%) cases. In the other 5 cases, this was over muscle or over permanent sutures. Focal cartilage necrosis was present in 2 (8%) of 24 cases, and was localized, self limiting, and deep to the endolaryngeal surface. When the TCF failed to survive histologically, poorer results for arytenoid replacement and pseudocord position generally resulted. However, this apparent difference was not statistically significant due to small sample sizes and variability in results. Other factors that may have kept this difference from becoming larger were thought to be contraction of the normal cord towards the operated side with foreshortening of the glottis, and medial rotation and ossification of the posterior thyroid ala remnant. Sternohyoid muscle flap reconstruction and endolaryngeal muscle coverage were also investigated. Bipedicled sternohyoid flaps exhibited no loss as compared to the contralateral bipedicled sternohyoid muscle used as a control. Unipedicled flaps lost 23% in cross-sectional area in the axial plane as compared to the bipedicled flaps used for reconstruction (P = .0423) and the contralateral bipedicled sternohyoid control (P = .0341). Three types of endolaryngeal muscle coverage were used: perichondrium, mucosa, and no coverage. The no-coverage group showed 16% less underlying sternohyoid muscle area than the perichondrium or mucosa groups, but this difference was not statistically significant. Nonkeratinizing stratified squamous epithelium was present over the muscle, but there were no differences in cell-layer thickness between perichondrium (5.8), mucosa (5.9), and no coverage (6.0). Cell-layer thickness over the opposite normal control mucosa (7.6) was significantly greater than either mucosa over muscle (5.9, P<.0001) or mucosa over the bony pseudocord (5.6, P = .0005). C1 WALTER REED ARMY MED CTR,OTOLARYNGOL HEAD & NECK SURG SERV,WASHINGTON,DC 20307. UNIFORMED SERV UNIV HLTH SCI,DEPT SURG,BETHESDA,MD 20814. RP BURGESS, LPA (reprint author), TRIPLER ARMY MED CTR,OTOLARYNGOL HEAD & NECK SURG SERV,TRIPLER,HI 96859, USA. NR 100 TC 17 Z9 17 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0023-852X J9 LARYNGOSCOPE JI Laryngoscope PD FEB PY 1993 VL 103 IS 2 BP 109 EP 132 PG 24 WC Medicine, Research & Experimental; Otorhinolaryngology SC Research & Experimental Medicine; Otorhinolaryngology GA KL154 UT WOS:A1993KL15400001 PM 8426502 ER PT J AU JONES, BH COWAN, DN TOMLINSON, JP ROBINSON, JR POLLY, DW FRYKMAN, PN AF JONES, BH COWAN, DN TOMLINSON, JP ROBINSON, JR POLLY, DW FRYKMAN, PN TI EPIDEMIOLOGY OF INJURIES ASSOCIATED WITH PHYSICAL-TRAINING AMONG YOUNG MEN IN THE ARMY SO MEDICINE AND SCIENCE IN SPORTS AND EXERCISE LA English DT Article DE MUSCULOSKELETAL INJURIES; LOWER EXTREMITY INJURIES; RISK FACTORS; EXERCISE; PHYSICAL ACTIVITY; INCIDENCE; MULTIVARIATE ANALYSIS ID ALL-CAUSE MORTALITY; STRESS-FRACTURES; EXERCISE; FITNESS; RISKS; BENEFITS; SPORTS; WOMEN; AGE AB It is widely acknowledged that musculoskeletal injuries occur as a result of vigorous physical activity and exercise, but little quantitative documentation exists on the incidence of or risk factors for these injuries. This study was conducted to assess the incidence, types, and risk factors for training-related injuries among young men undergoing Army infantry basic training. Prior to training we evaluated 303 men (median age 19 yr), utilizing questionnaires and measurements of physical fitness. Subjects were followed over 12 wk of training. Physical training was documented on a daily basis, and injuries were ascertained by review of medical records for every trainee. We performed univariate and multivariate analyses of the data. Cumulative incidence of subjects with one or more lower extremity training-related injury was 37% (80% of all injuries). The most common injuries were muscle strains, sprains, and overuse knee conditions. A number of risk factors were identified, including: older age, smoking, previous injury (sprained ankles), low levels of previous occupational and physical activity, low frequency of running before entry into the Army, flexibility (both high and low), low physical fitness on entry, and unit training (high running mileage). RP JONES, BH (reprint author), USA,ENVIRONM MED RES INST,DIV OCCUPAT MED,NATICK,MA 01760, USA. NR 37 TC 230 Z9 236 U1 10 U2 88 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0195-9131 J9 MED SCI SPORT EXER JI Med. Sci. Sports Exerc. PD FEB PY 1993 VL 25 IS 2 BP 197 EP 203 PG 7 WC Sport Sciences SC Sport Sciences GA KM063 UT WOS:A1993KM06300005 PM 8450721 ER PT J AU JEFFER, EK AF JEFFER, EK TI AGAINST MEDICAL ADVICE .1. A REVIEW OF THE LITERATURE SO MILITARY MEDICINE LA English DT Review AB As a preliminary step to studying the Army's experience with against medical advice (AMA) discharges, the literature was reviewed. Fifty-one articles were found through a computer program search. These articles reported widely varying rates depending upon the type of patient, primary diagnosis, and type of setting. Patients with drug and/or alcohol abuse problems are at significantly higher risk for AMA. No civilian studies have been identified which evaluate long-term trends. RP JEFFER, EK (reprint author), USA,NATL GUARD,4501 FORD AVE,PK CTR 4,ALEXANDRIA,VA 22302, USA. NR 0 TC 12 Z9 13 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD FEB PY 1993 VL 158 IS 2 BP 69 EP 73 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA KM459 UT WOS:A1993KM45900006 PM 8441499 ER PT J AU JEFFER, EK AF JEFFER, EK TI AGAINST MEDICAL ADVICE .2. THE ARMY EXPERIENCE 1971-1988 SO MILITARY MEDICINE LA English DT Article AB The Army experience with discharges against medical advice (AMA) from 1971 to 1988 is analyzed. AMA discharges have declined in a statistically significant manner in both medical centers and community hospitals. Discharges have decreased among men but increased among women. AMA discharges have decreased for both blacks and whites. Among clinical services, only obstetrics and gynecology demonstrated statistically significant increases. Among patient categories, only family members showed an increase. The possible sources of these various changes are discussed. RP JEFFER, EK (reprint author), USA,NATL GUARD,NATL GUARD BUR,4501 FORD AVE,ALEXANDRIA,VA 22302, USA. NR 0 TC 4 Z9 4 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD FEB PY 1993 VL 158 IS 2 BP 73 EP 76 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA KM459 UT WOS:A1993KM45900007 PM 8441500 ER PT J AU ILLICH, SJ KOTZIN, DA EDWARDS, MS AF ILLICH, SJ KOTZIN, DA EDWARDS, MS TI PHARMACY - THE SAUDI EXPERIENCE SO MILITARY MEDICINE LA English DT Article RP ILLICH, SJ (reprint author), USA,MEDDAC,PHARM SERV,PT CARSON,CO 80913, USA. NR 0 TC 2 Z9 2 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD FEB PY 1993 VL 158 IS 2 BP 96 EP 99 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA KM459 UT WOS:A1993KM45900012 PM 8441506 ER PT J AU PENNINGTON, GM DANLEY, DL SUMKO, MH BUCKNELL, A NELSON, JH AF PENNINGTON, GM DANLEY, DL SUMKO, MH BUCKNELL, A NELSON, JH TI PULSED, NONTHERMAL, HIGH-FREQUENCY ELECTROMAGNETIC ENERGY (DIAPULSE) IN THE TREATMENT OF GRADE-I AND GRADE-II ANKLE SPRAINS SO MILITARY MEDICINE LA English DT Article AB Acutely sprained ankles represent a frequent and common injury among active duty troops in training, and are a significant source of morbidity with respect to days lost to training. Swelling in the form of periarticular edema limits motion, causes pain, prevents wearing of normal foot gear, and slows the healing process. Reduction of edema was attempted in acutely sprained ankles by the use of pulsed electromagnetic energy (Diapulse). In a randomized, prospective, double blind study of 50 grade I and II (no gross instability) sprained ankles, a statistically significant (p < 0.01) decrease in edema was noted following one treatment with Diapulse. The application of this modality in acutely sprained ankles could result in significant decreases in time lost to military training. RP PENNINGTON, GM (reprint author), BROOKE ARMY MED CTR,ORTHOPED SURG SERV,FT SAM HOUSTON,TX 78234, USA. NR 0 TC 31 Z9 33 U1 0 U2 1 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD FEB PY 1993 VL 158 IS 2 BP 101 EP 104 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA KM459 UT WOS:A1993KM45900014 PM 8441490 ER PT J AU PIERCE, JR AF PIERCE, JR TI THE ROLE OF THE UNITED-STATES-ARMY ACTIVE COMPONENT PEDIATRICIANS IN OPERATIONS DESERT SHIELD, DESERT STORM, AND PROVIDE COMFORT SO MILITARY MEDICINE LA English DT Article AB The professional activities and experiences of Army active component pediatricians deployed to Southwest Asia in support of Operations Desert Shield, Desert Storm, and Provide Comfort are reported. The 37 pediatricians who served in Southwest Asia were surveyed by a voluntary questionnaire. The survey revealed that Army pediatricians played an important role in these operations and in supporting the combat forces in Southwest Asia. They also played a critical role in caring for children displaced by the war and its aftermath in southern and northern Iraq. Pediatricians played an equally important role in continuing to provide care and support for the family members left behind in the United States and Europe, RP PIERCE, JR (reprint author), WALTER REED ARMY MED CTR,DEPT PEDIAT,WASHINGTON,DC 20307, USA. NR 0 TC 4 Z9 4 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD FEB PY 1993 VL 158 IS 2 BP 105 EP 108 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA KM459 UT WOS:A1993KM45900015 PM 8441491 ER PT J AU STONG, GC KALENIAN, MH HOPE, JW AF STONG, GC KALENIAN, MH HOPE, JW TI MEDICAL EVACUATION EXPERIENCE OF 2 7TH CORPS MEDICAL COMPANIES SUPPORTING DESERT SHIELD DESERT STORM SO MILITARY MEDICINE LA English DT Article AB Examining medical evacuation data in the high-intensity conflict environment of Desert Shield/Desert Storm yielded some interesting findings. Motor vehicle accidents accounted for most precombat injuries. The combat period was markedly more intense than the other periods and must be the focal point for planning. Indigenous civilians and prisoners of war accounted for a large portion of casualties during and after the combat phases. Mission coordination was a major problem until a central dispatch agency was organized. Ambulance exchange points lacked communication and triage capability, limiting multiple patient transfer and long-haul efficiency. Other problems included lack of translators for civilian casualties and inadequate passenger restraints in some ground vehicles. RP STONG, GC (reprint author), BROOKE ARMY MED CTR,DEPT ANAT PATHOL,FT SAM HOUSTON,TX 78234, USA. NR 0 TC 9 Z9 9 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD FEB PY 1993 VL 158 IS 2 BP 108 EP 113 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA KM459 UT WOS:A1993KM45900016 PM 8441492 ER PT J AU ROY, MJ JACOBY, I AF ROY, MJ JACOBY, I TI THE PATIENT SELF-DETERMINATION ACT - IS IT ALL IT CAN BE SO MILITARY MEDICINE LA English DT Editorial Material RP ROY, MJ (reprint author), WALTER REED ARMY MED CTR,DEPT MED,WASHINGTON,DC 20307, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD FEB PY 1993 VL 158 IS 2 BP 128 EP 129 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA KM459 UT WOS:A1993KM45900022 PM 8441498 ER PT J AU BERNING, PR NIILER, A AF BERNING, PR NIILER, A TI BACKSCATTERING ANALYSIS OF THIN-FILMS ON NON-FLAT SURFACES SO NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS LA English DT Article ID RUTHERFORD BACKSCATTERING; SIMULATION; SPECTRA AB In order to allow for the analysis of contaminant layers on powder surfaces, methods of adapting ion beam analysis techniques for use on non-flat surfaces have been developed. In this work, particular attention is given to situations where the dimensions of the surface structures are much larger than the thickness of the film, but much smaller than the ion beam spot size. It is assumed that the surface material is conformal and evenly distributed across the surface. Two methods are discussed; both are designed to analyze backscattered ion energy spectra through the use of available simulation programs. Two methods rely on a knowledge of the distribution of surface-normal to beam-direction angles present on the surface shape to be studied. Examples of this and other relevant distribution functions corresponding to several types of surface shape will be shown. The methods described here are used to study oxide layers grown thermally on small (almost-equal-to 130 mum) spherical titanium powder particles. We also show examples of how to empirically determine the distribution of surface tilt angles present on a surface of unknown shape when the nature of the surface film is known. RP BERNING, PR (reprint author), USA,BALLIST RES LAB,ABERDEEN PROVING GROUND,MD 21005, USA. NR 16 TC 5 Z9 5 U1 1 U2 2 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0168-583X J9 NUCL INSTRUM METH B JI Nucl. Instrum. Methods Phys. Res. Sect. B-Beam Interact. Mater. Atoms PD FEB PY 1993 VL 73 IS 2 BP 178 EP 190 PG 13 WC Instruments & Instrumentation; Nuclear Science & Technology; Physics, Atomic, Molecular & Chemical; Physics, Nuclear SC Instruments & Instrumentation; Nuclear Science & Technology; Physics GA KL011 UT WOS:A1993KL01100011 ER PT J AU JARRETT, RV MARINKOVICH, GA GAYLE, EL BASS, JW AF JARRETT, RV MARINKOVICH, GA GAYLE, EL BASS, JW TI INDIVIDUALIZED PHARMACOKINETIC PROFILES TO COMPUTE VANCOMYCIN DOSAGE AND DOSING INTERVAL IN PRETERM INFANTS SO PEDIATRIC INFECTIOUS DISEASE JOURNAL LA English DT Note DE NEWBORN; PHARMACOKINETICS; VANCOMYCIN ID CLINICAL-PHARMACOLOGY; RECOMMENDATIONS C1 TRIPLER ARMY MED CTR,DEPT PATHOL,HONOLULU,HI 96859. RP JARRETT, RV (reprint author), TRIPLER ARMY MED CTR,DEPT PEDIAT,HONOLULU,HI 96859, USA. NR 15 TC 10 Z9 10 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0891-3668 J9 PEDIATR INFECT DIS J JI Pediatr. Infect. Dis. J. PD FEB PY 1993 VL 12 IS 2 BP 156 EP 157 DI 10.1097/00006454-199302000-00010 PG 2 WC Immunology; Infectious Diseases; Pediatrics SC Immunology; Infectious Diseases; Pediatrics GA KM096 UT WOS:A1993KM09600010 PM 8426775 ER PT J AU SOUTHGATE, WM PICHOFF, BE STEVENS, EL BALARAMAN, V UYEHARA, CFT NAKAMURA, KT AF SOUTHGATE, WM PICHOFF, BE STEVENS, EL BALARAMAN, V UYEHARA, CFT NAKAMURA, KT TI ONTOGENY OF EPITHELIAL MODULATION OF AIRWAY SMOOTH-MUSCLE FUNCTION IN THE GUINEA-PIG SO PEDIATRIC PULMONOLOGY LA English DT Article DE ISOMETRIC TENSION (TRACHEAL RING MUSCLE); ACH, HI CUMULATIVE DOSE RESPONSE; AGE-RELATED DIFFERENCES ID AGE-RELATED ALTERATIONS; RESPIRATORY EPITHELIUM; ISOLATED TRACHEALIS; RESPONSIVENESS; REMOVAL; CONTRACTION; RESPONSES; TISSUES; SENSITIVITY; MATURATION AB The purpose of this study was to investigate the ontogeny of guinea pig airway smooth muscle (ASM) responses and the epithelial modulation of these responses. Paired tracheal rings from fetal, newborn, and adult guinea pigs were studied. One of each pair was denuded of airway epithelium (AE) by gentle rubbing. Isometric tension was measured in rings mounted in organ baths filled with Krebs' solution. Cumulative dose-response curves were generated by adding either acetylcholine (ACh) or histamine over a concentration range of 10(-8)-10(-4) M. Significant agent-specific, age-related differences in maximal contraction were seen for both ACh and histamine in intact tissues (Ach: for fetus 66.7 +/- 6.2 x 10(-2) g/Mg wet wt, for newborn 51.4 +/- 6.2, for adult 29.3 +/- 2.6; histamine: for fetus 46.1 +/- 5.1, for newborn 72.9 +/- 6.0, for adult 25.3 +/- 3.2). Similar differences in sensitivity to both agents were observed (EC50 with ACh: for fetus 0.80 +/- 0.11 X 10(-6) M; for newborn 0.85 +/- 0.26 x 10(-6) M; for adult 1.7 +/- 0.20 x 10(-6) M; EC50 with histamine: for fetus 1.88 +/- 0.50 x 10(-6) M; for newborn 1.34 +/- 0.16 x 10(-6) M; for adult 3.78 +/- 0.75 x 10(-6) M). Removal of AE caused a significant decrease in maximal responses to ACh in fetal tissue, a smaller, insignificant one for newborn and a nonsignificant alteration for adult tissues. Age-related sensitivity difference was abolished with removal of AE to ACh but not to histamine. In conclusion, during development (1) maximum tension, expressed as force per tissue weight, when generated follows the pattern, fetus > newborn > adult with ACh and newborn > fetus > adult with histamine; (2) the EC50 pattern for both ACh and histamine was, fetus = newborn < adult; (3) for denuded tissue maximum tension by ACh was significantly decreased only in fetal trachea; and (4) removal of AE abolished the age-dependent difference in sensitivity to ACh, but not to histamine. C1 KAPIOLANI MED CTR WOMEN & CHILDREN,DEPT PEDIAT,1319 PUNAHOU ST,RM 731,HONOLULU,HI 96826. JOHN A BURNS SCH MED,HONOLULU,HI. TRIPLER ARMY MED CTR,DEPT PEDIAT & CLIN INVEST,HONOLULU,HI 96859. FU NHLBI NIH HHS [HL-45220] NR 32 TC 9 Z9 9 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 8755-6863 J9 PEDIATR PULM JI Pediatr. Pulmonol. PD FEB PY 1993 VL 15 IS 2 BP 105 EP 110 DI 10.1002/ppul.1950150207 PG 6 WC Pediatrics; Respiratory System SC Pediatrics; Respiratory System GA KN869 UT WOS:A1993KN86900006 PM 8474781 ER PT J AU KANT, GJ AF KANT, GJ TI EFFECTS OF PSYCHOACTIVE-DRUGS OR STRESS ON LEARNING, MEMORY, AND PERFORMANCE AS ASSESSED USING A NOVEL WATER MAZE TASK SO PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR LA English DT Article DE LEARNING; MEMORY; PERFORMANCE; WATER MAZE; STRESS; AMPHETAMINE; DIAZEPAM; CAFFEINE; ATROPINE ID ACQUISITION; RAT; CAFFEINE; DIAZEPAM; BLOCKADE AB A novel water maze was used to assess the potential performance-disrupting effects of psychoactive drugs and stressors (4 mg/kg amphetamine sulfate; 1, 2, or 4 mg/kg diazepam; 30 mg/kg caffeine; 5 or 30 mg/kg atropine sulfate; 15 min of either intermittent foot-shock, forced running, or immobilization). The task utilized a traditional type of maze with walls and doorways set inside a pool. The apparatus could easily be reconfigured to present different mazes of approximately equal difficulty by opening or closing multiple doorways. Performance was measured by number of errors and time required to swim from the ''start'' to ''finish'' (a raised platform not in the rat's line of sight). After initial maze training, rats were divided into two groups. One group ran three daily trials through the same maze each day; this group was used to assess memory. The second group was challenged to swim three consecutive trials in a new maze configuration each day as a measure of learning. On any given day, rats from both groups received the same treatment. Drug or stress treatments were interspersed with vehicle or no-treatment trial days. The new maze task was more sensitive than the well-learned maze to the performance-disrupting effects of amphetamine, caffeine, and diazepam, while atropine had no significant effect on performance on either maze. Foot-shock stress impaired performance on both mazes, while the other stressors had no significant effect. RP KANT, GJ (reprint author), WALTER REED ARMY INST RES,DEPT MED NEUROSCI,WASHINGTON,DC 20307, USA. NR 18 TC 20 Z9 20 U1 2 U2 5 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0091-3057 J9 PHARMACOL BIOCHEM BE JI Pharmacol. Biochem. Behav. PD FEB PY 1993 VL 44 IS 2 BP 287 EP 295 PG 9 WC Behavioral Sciences; Neurosciences; Pharmacology & Pharmacy SC Behavioral Sciences; Neurosciences & Neurology; Pharmacology & Pharmacy GA KM966 UT WOS:A1993KM96600007 PM 8446662 ER PT J AU BOWDEN, CM DOWLING, JP AF BOWDEN, CM DOWLING, JP TI NEAR DIPOLE-DIPOLE EFFECTS IN DENSE MEDIA - GENERALIZED MAXWELL-BLOCH EQUATIONS SO PHYSICAL REVIEW A LA English DT Article ID MIRRORLESS OPTICAL BISTABILITY; FINITE MOLECULAR FLUID; LOCAL-FIELD CORRECTION; SCATTERING; LIGHT AB A self-consistent generalization of the Maxwell-Bloch formulation is presented here for a nonlinear system of saturable two-level atoms interacting with the electromagnetic field, under the condition that the atomic density is such that there are, on the average, many atoms within a cubic resonance wave-length such that near-dipole-dipole interactions, which lead to local-field corrections, cannot be neglected. RP BOWDEN, CM (reprint author), USA,MISSILE RES & DEV COMMAND,CTR RES DEV & ENGN,WEAP SCI DIRECTORATE,AMSMI RD WS ST,REDSTONE ARSENAL,AL 35809, USA. RI DOWLING, JONATHAN/L-2749-2013 NR 27 TC 172 Z9 180 U1 0 U2 5 PU AMERICAN PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1050-2947 J9 PHYS REV A JI Phys. Rev. A PD FEB PY 1993 VL 47 IS 2 BP 1247 EP 1251 DI 10.1103/PhysRevA.47.1247 PG 5 WC Optics; Physics, Atomic, Molecular & Chemical SC Optics; Physics GA KV979 UT WOS:A1993KV97900068 ER PT J AU GALLOWAY, GE AF GALLOWAY, GE TI TERRAIN AND TACTICS - OSULLIVAN,P SO PROFESSIONAL GEOGRAPHER LA English DT Book Review DE MILITARY GEOGRAPHY; TERRAIN; WAR; TACTICS; TERRORISM; POWER RP GALLOWAY, GE (reprint author), US MIL ACAD,W POINT,NY 10996, USA. NR 1 TC 0 Z9 0 U1 0 U2 2 PU BLACKWELL PUBLISHERS PI CAMBRIDGE PA 350 MAIN STREET, STE 6, CAMBRIDGE, MA 02148-5023 SN 0033-0124 J9 PROF GEOGR JI Prof. Geogr. PD FEB PY 1993 VL 45 IS 1 BP 120 EP 121 PG 2 WC Geography SC Geography GA KM923 UT WOS:A1993KM92300039 ER PT J AU PESCERODRIGUEZ, RA FIFER, RA AF PESCERODRIGUEZ, RA FIFER, RA TI PYROLYTIC DECOMPOSITION OF SOLID-PROPELLANTS SO PURE AND APPLIED CHEMISTRY LA English DT Article ID THERMAL-DECOMPOSITION; MELTING POINT; RDX; TEMPERATURES AB Pyrolysis - gas chromatography - Fourier transform infrared (P-GC-FTIR) spectroscopy has been used to examine the pyrolysis product distributions of a composite propellant formulation series. The series was formulated with the oxidizers HMX and RDX, the polymers GAP, HTPB, BAMO/AMMO, and BAMO/THF, and the plasticizers BTTN and TMETN. Trends in product distribution as a function of formulation, as well as correlations between radiative ignition times and pyrolysis products were identified. The most noteworthy correlations observed were between the amounts of permanent gases and amides produced and go/no-go ignition time. In general, pyrolysis product distribution were found to be most strongly affected by the presence and type of plasticizer. RP PESCERODRIGUEZ, RA (reprint author), USA,BALLIST RES LABS,ABERDEEN PROVING GROUND,MD 21005, USA. NR 9 TC 1 Z9 1 U1 2 U2 3 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0033-4545 J9 PURE APPL CHEM JI Pure Appl. Chem. PD FEB PY 1993 VL 65 IS 2 BP 317 EP 323 DI 10.1351/pac199365020317 PG 7 WC Chemistry, Multidisciplinary SC Chemistry GA KJ669 UT WOS:A1993KJ66900017 ER PT J AU LYON, RD MCADAMS, HP AF LYON, RD MCADAMS, HP TI MEDIASTINAL BRONCHOGENIC CYST - DEMONSTRATION OF A FLUID-FLUID LEVEL AT MR IMAGING SO RADIOLOGY LA English DT Article DE BRONCHI, CYSTS; MEDIASTINUM, MR ID CT AB The appearance of mediastinal bronchogenic cysts at cross-sectional imaging is variable. Intracystic hemorrhage, proteinaceous fluid, or suspended calcium may belie the true cystic nature of the lesion at computed tomography or magnetic resonance (MR) imaging. The authors report a case of a fluid-fluid level seen on MR images of a bronchogenic cyst. This appearance, likely due to dependent layering of proteinaceous material, helped preoperatively confirm the true cystic nature of the lesion. C1 UNIFORMED SERV UNIV HLTH SCI,DEPT RADIOL,BETHESDA,MD 20814. RP LYON, RD (reprint author), WALTER REED ARMY MED CTR,DEPT RADIOL,WASHINGTON,DC 20307, USA. RI McAdams, Holman/N-8218-2015 OI McAdams, Holman/0000-0002-7044-3320 NR 8 TC 25 Z9 27 U1 0 U2 0 PU RADIOLOGICAL SOC NORTH AMER PI EASTON PA 20TH AND NORTHAMPTON STS, EASTON, PA 18042 SN 0033-8419 J9 RADIOLOGY JI Radiology PD FEB PY 1993 VL 186 IS 2 BP 427 EP 428 PG 2 WC Radiology, Nuclear Medicine & Medical Imaging SC Radiology, Nuclear Medicine & Medical Imaging GA KH843 UT WOS:A1993KH84300028 PM 8421745 ER PT J AU MOREY, AF LECKIE, R ADAMS, SD KENNON, WG MURPHY, T AF MOREY, AF LECKIE, R ADAMS, SD KENNON, WG MURPHY, T TI CLINICAL URORADIOLOGIC CONFERENCE .14. EXTENSIVE RETROPERITONEAL MASS SO UROLOGY LA English DT Discussion ID XANTHOGRANULOMATOUS PYELONEPHRITIS C1 TRIPLER ARMY MED CTR,DEPT RADIOL,HONOLULU,HI 96859. TRIPLER ARMY MED CTR,DEPT PATHOL,HONOLULU,HI 96859. RP MOREY, AF (reprint author), TRIPLER ARMY MED CTR,DEPT SURG,UROL SERV,HONOLULU,HI 96859, USA. NR 5 TC 1 Z9 1 U1 0 U2 0 PU CAHNERS PUBL CO PI NEW YORK PA 249 WEST 17 STREET, NEW YORK, NY 10011 SN 0090-4295 J9 UROLOGY JI UROLOGY PD FEB PY 1993 VL 41 IS 2 BP 185 EP 188 DI 10.1016/0090-4295(93)90178-D PG 4 WC Urology & Nephrology SC Urology & Nephrology GA KW025 UT WOS:A1993KW02500023 PM 8497996 ER PT J AU LACEY, PI AF LACEY, PI TI WEAR WITH LOW-LUBRICITY FUELS .1. DEVELOPMENT OF A WEAR MAPPING TECHNIQUE SO WEAR LA English DT Article ID MAPS AB Use of low-lubricity fuels such as Jet A-1 is now relatively common in military ground equipment, while severe refinery processes such as hydrotreating are removing reactive components from commercially available diesel fuels. Under critical conditions, durability problems with fuel-sensitive equipment emerge with the use of Jet A-1. Consequently, a bench wear test that accurately reflects the environment within the fuel injection system is needed. However, a better understanding of the primary wear mechanisms present in the fuel injection system and their relationship with potential bench wear tests is first required. Wear maps have previously been used to study ceramic materials and to define the wear mechanisms in metallic contacts. This technique systematically produces a data base according to a self-consistent methodology and allows the effects of each contact parameter to be precisely described. This paper, the first of two, details the initial test development required to ensure that the data base is completed according to a single well-defined procedure. The second paper, ''Correlation between wear maps and pump components'', uses the test methodologies and results developed to elucidate the wear mechanisms present in fuel-lubricated contacts and to assist in bridging the gap between laboratory tests and practical applications. RP LACEY, PI (reprint author), USA,BELVOIR FUELS & LUBRICANTS RES FACIL,SW RES INST,SAN ANTONIO,TX, USA. NR 17 TC 12 Z9 12 U1 1 U2 4 PU ELSEVIER SCIENCE SA LAUSANNE PI LAUSANNE 1 PA PO BOX 564, 1001 LAUSANNE 1, SWITZERLAND SN 0043-1648 J9 WEAR JI Wear PD FEB 1 PY 1993 VL 160 IS 2 BP 325 EP 332 DI 10.1016/0043-1648(93)90437-Q PG 8 WC Engineering, Mechanical; Materials Science, Multidisciplinary SC Engineering; Materials Science GA KN640 UT WOS:A1993KN64000016 ER PT J AU LACEY, PI AF LACEY, PI TI WEAR WITH LOW-LUBRICITY FUELS .2. CORRELATION BETWEEN WEAR MAPS AND PUMP COMPONENTS SO WEAR LA English DT Article AB Increasingly severe refinery processes remove many of the compounds necessary for effective lubrication with diesel fuels. No widely recognized lubricity test or standard currently exists relating to the needs of the fuel injection system on compression ignition equipment. The Ball-on-Cylinder Lubricity Evaluator (BOCLE) is commonly used by the US Air Force to measure aviation turbine fuel lubricity. However, the tribological requirements of fuel-lubricated components in aviation may not coincide with the needs of ground vehicles. This study uses the wear-mapping technique developed in the preceding paper (''Development of a wear mapping technique'') to indicate the significance of the BOCLE test methodology in this context. In particular, the work highlights the effects of various contact parameters on fuel-lubricated wear that are not revealed by the BOCLE results. Where possible, both the BOCLE and wear map data are compared with the results of full-scale pump stand tests detailed in the previous paper. Additional nonstandard bench wear tests were performed to further evaluate the contact conditions present within the operating pump. The wear mechanisms of each fluid were determined to be strong functions of both metallurgy and contact stress. Moreover, the onset and severity of each wear mechanism appear to be controlled by different fuel properties. As a result, the relative lubricity observed between fuels depends on the test conditions chosen so it is unlikely that fuel lubricity may be uniquely defined by a single bench wear test procedure. RP LACEY, PI (reprint author), USA,BELVOIR FUELS & LUBRICANTS RES FACIL,SW RES INST,SAN ANTONIO,TX, USA. NR 41 TC 8 Z9 8 U1 3 U2 6 PU ELSEVIER SCIENCE SA LAUSANNE PI LAUSANNE 1 PA PO BOX 564, 1001 LAUSANNE 1, SWITZERLAND SN 0043-1648 J9 WEAR JI Wear PD FEB 1 PY 1993 VL 160 IS 2 BP 333 EP 343 DI 10.1016/0043-1648(93)90438-R PG 11 WC Engineering, Mechanical; Materials Science, Multidisciplinary SC Engineering; Materials Science GA KN640 UT WOS:A1993KN64000017 ER PT J AU SMITH, TT AF SMITH, TT TI THE CUSTER READER - HUTTON,PA SO WESTERN HISTORICAL QUARTERLY LA English DT Book Review RP SMITH, TT (reprint author), US MIL ACAD,W POINT,NY 10996, USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU WESTERN HISTORY ASSOCIATION PI LOGAN PA UTAH STATE UNIV, UMC 0740, LOGAN, UT 84322 SN 0043-3810 J9 WESTERN HIST QUART JI West. Hist. Q. PD FEB PY 1993 VL 24 IS 1 BP 108 EP 109 PG 2 WC History SC History GA KM780 UT WOS:A1993KM78000043 ER PT J AU WASSEF, NM SWARTZ, GM ALVING, BM ALVING, CR AF WASSEF, NM SWARTZ, GM ALVING, BM ALVING, CR TI ATP SPECIFICALLY BOUND AS A HAPTEN TO A MONOCLONAL ANTIPHOSPHOLIPID ANTIBODY RETAINS PHOSPHATE DONOR ACTIVITY SO BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS LA English DT Article ID SPHINGOMYELIN-CONTAINING LIPOSOMES; DEPENDENT TRANSPORT-SYSTEMS; PHOSPHATIDYLINOSITOL PHOSPHATE; RABBIT ANTIBODIES; LIPID-A; BINDING; PHOSPHOCHOLINE C1 WALTER REED ARMY INST RES,DEPT HEMATOL,WASHINGTON,DC 20307. RP WASSEF, NM (reprint author), WALTER REED ARMY INST RES,DEPT MEMBRANE BIOCHEM,WASHINGTON,DC 20307, USA. NR 23 TC 6 Z9 6 U1 0 U2 0 PU ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 SN 0006-291X J9 BIOCHEM BIOPH RES CO JI Biochem. Biophys. Res. Commun. PD JAN 29 PY 1993 VL 190 IS 2 BP 582 EP 588 DI 10.1006/bbrc.1993.1088 PG 7 WC Biochemistry & Molecular Biology; Biophysics SC Biochemistry & Molecular Biology; Biophysics GA KK585 UT WOS:A1993KK58500040 PM 8381281 ER PT J AU WEINSTEIN, PD ANDERSON, AO MAGE, RG AF WEINSTEIN, PD ANDERSON, AO MAGE, RG TI MOLECULAR GENETIC DIVERSIFICATION OF VARIABLE REGION GENES FROM GALT B-CELLS RESPONDING TO ENVIRONMENT ANTIGENS IN THE 2 PRIMARY GERMINAL CENTER COMPARTMENTS SO JOURNAL OF CELLULAR BIOCHEMISTRY LA English DT Meeting Abstract C1 NIAID,LI,BETHESDA,MD 20892. USA,MRIID,DAD,FREDERICK,MD 21702. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0730-2312 J9 J CELL BIOCHEM JI J. Cell. Biochem. PD JAN 26 PY 1993 SU 17B BP 223 EP 223 PG 1 WC Biochemistry & Molecular Biology; Cell Biology SC Biochemistry & Molecular Biology; Cell Biology GA KN465 UT WOS:A1993KN46500796 ER PT J AU DELORIMIER, A PARK, F ARANHA, GV REYES, C AF DELORIMIER, A PARK, F ARANHA, GV REYES, C TI HEPATOID CARCINOMA OF THE STOMACH SO CANCER LA English DT Article DE HEPATOID; ADENOCARCINOMA OF STOMACH; ALPHA-FETOPROTEIN; LIVER METASTASIS ID GASTRIC ADENOCARCINOMA; ALPHA-FETOPROTEIN; DIFFERENTIATION; CANCER AB A patient with primary gastric carcinoma exhibiting hepatoid differentiation is described. The tumor itself was not associated with a high serum alpha-fetoprotein, but the cells stained positive for alpha-fetoprotein and alpha-1 antitrypsin. The patient underwent a total gastrectomy and wedge excision of the liver metastasis. The presence of metastatic hepatoid adenocarcinoma of the stomach should be considered in a patient who, during surgery for a primary gastric carcinoma, is found to have a liver metastasis that is diagnosed by frozen-section biopsy as a hepatoma. Because of lymph node and liver metastasis, prognosis appears to be poor for such patients. C1 LOYOLA UNIV,MED CTR,2160 S 1ST AVE,MAYWOOD,IL 60153. TRIPLER ARMY MED CTR,TRIPLER,HI. VET ADM MED CTR,HINES,IL 60141. NR 7 TC 34 Z9 35 U1 1 U2 1 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0008-543X J9 CANCER JI Cancer PD JAN 15 PY 1993 VL 71 IS 2 BP 293 EP 296 DI 10.1002/1097-0142(19930115)71:2<293::AID-CNCR2820710204>3.0.CO;2-O PG 4 WC Oncology SC Oncology GA KG998 UT WOS:A1993KG99800003 PM 7678544 ER PT J AU BERI, RG WALKER, J REESE, ET ROLLINGS, JE AF BERI, RG WALKER, J REESE, ET ROLLINGS, JE TI CHARACTERIZATION OF CHITOSANS VIA COUPLED SIZE-EXCLUSION CHROMATOGRAPHY AND MULTIPLE-ANGLE LASER LIGHT-SCATTERING TECHNIQUE SO CARBOHYDRATE RESEARCH LA English DT Article ID GEL-PERMEATION CHROMATOGRAPHY; MOLECULAR-WEIGHT; PENICILLIUM-ISLANDICUM; DEACETYLATED CHITOSAN; SMALL PORES; POLYMER; PURIFICATION; TRANSPORT; VISCOSITY; MODE AB Chitosan [(1 --> 4)-2-amino-2-deoxy-beta-D-glucan], a cationic biopolymer, was obtained by deacetylation of chitin samples from various sources. Nine chitosan samples differing in their degree of acetylation and molecular weight were used in this study. They were characterized by size-exclusion chromatography (SEC) coupled to a multiple-angle laser light-scattering (MALLS) photometer. The results show that accurate, reliable, and reproducible molecular weight and radius of gyration data are obtained by using SEC-MALLS. These samples were also characterized by a conventional secondary calibration technique. The molecular weights obtained by secondary calibration were found to be 2-3 times higher than those obtained using SEC-MALLS. The dissimilarity between the chitosan samples and polymer standards employed for calibration were presumed to be responsible for overestimation of the molecular weights. Therefore, we conclude that the unavailability of chitosan polymer standards underscores the need of an absolute molecular-weight determination technique, such as SEC-MALLS. This technique can be used for establishing structure-function relationships of chitosans and as a quality control tool for monitoring bulk production of chitosans. C1 WORCESTER POLYTECH INST, DEPT CHEM ENGN, WORCESTER, MA 01609 USA. USA, RD & E LABS, SOLDIER SCI DIRECTORATE, NATICK, MA 01760 USA. NR 37 TC 63 Z9 63 U1 1 U2 8 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND SN 0008-6215 EI 1873-426X J9 CARBOHYD RES JI Carbohydr. Res. PD JAN 15 PY 1993 VL 238 BP 11 EP 26 DI 10.1016/0008-6215(93)87002-A PG 16 WC Biochemistry & Molecular Biology; Chemistry, Applied; Chemistry, Organic SC Biochemistry & Molecular Biology; Chemistry GA KK472 UT WOS:A1993KK47200002 ER PT J AU DANDEKAR, DP BENFANTI, DC AF DANDEKAR, DP BENFANTI, DC TI STRENGTH OF TITANIUM DIBORIDE UNDER SHOCK-WAVE LOADING SO JOURNAL OF APPLIED PHYSICS LA English DT Article AB Strength of TiB2 under plane shock wave loading is assessed in terms of its spall threshold and the shear stress sustained by it under shock compression to 60 GPa. The results of experiments support the thesis that the observed cusp in TiB2 at 4.5-7.0 GPa is of mechanical nature and its effect is to decrease the spall threshold values at stresses above the cusp but below the accepted Hugoniot elastic limit (HEL) value of 13-17 GPa. A comparison of shock Hugoniot data on two different TiB2 obtained from Grady [Dynamic Material Properties of Armor Ceramics, Sandia Laboratories, SAND 91-0147. UC-704 (1991)] and the adiabats constructed from high pressure ultrasonic wave velocity measurements show that these materials sustain increasing shear stresses with increasing values of shock stress. For example, results of data analysis on the denser TiB2 show that it sustains around three times the shear stress at 60 GPa than at its HEL, i.e., 17 GPa. RP DANDEKAR, DP (reprint author), USA,MAT TECHNOL LAB,WATERTOWN,MA 02172, USA. NR 18 TC 31 Z9 31 U1 1 U2 3 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0021-8979 J9 J APPL PHYS JI J. Appl. Phys. PD JAN 15 PY 1993 VL 73 IS 2 BP 673 EP 679 DI 10.1063/1.353350 PG 7 WC Physics, Applied SC Physics GA KG476 UT WOS:A1993KG47600024 ER PT J AU BRONK, BV SMITH, MJ ARNOLD, S AF BRONK, BV SMITH, MJ ARNOLD, S TI PHOTON-CORRELATION SPECTROSCOPY FOR SMALL SPHERICAL INCLUSIONS IN A MICROMETER-SIZED ELECTRODYNAMICALLY LEVITATED DROPLET SO OPTICS LETTERS LA English DT Article ID SINGLE AEROSOL-PARTICLE; MICROPARTICLE AB Micrometer-sized droplets of saturated sodium chloride solution were captured in an electrodynamic levitator and maintained at constant diameter for several days at a time. Both pure droplets and droplets containing 0.5-mum subparticles (guests) were studied by means of 90-deg scattering of polarized laser light. Analysis of the correlation function for the intensity of the scattered light gave characteristic decay times of approximately 9 ms, which has a good correspondence with the physical parameters of the solution and the size of the subparticles. Longer characteristic times are measures of morphological features of the electromagnetic field intensity in the host particles. A new phenomenon was observed when the exit polarizer was crossed to the input polarization. Scattered light corresponding to light from the guest particles could only be visualized from a shell near the exterior of the sphere and not from the interior of the host droplet. C1 SUNY BROOKLYN POLYTECH,MICROPARTICLE PHOTOPHYS LAB,BROOKLYN,NY 11201. RP BRONK, BV (reprint author), USA,CTR CHEM RES DEV & ENGN,ABERDEEN PROVING GROUND,MD 21010, USA. NR 15 TC 34 Z9 34 U1 0 U2 3 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 SN 0146-9592 J9 OPT LETT JI Opt. Lett. PD JAN 15 PY 1993 VL 18 IS 2 BP 93 EP 95 DI 10.1364/OL.18.000093 PG 3 WC Optics SC Optics GA KG085 UT WOS:A1993KG08500003 PM 19802048 ER PT J AU ARMSTRONG, RL XIE, JG RUEKGAUER, TE GU, J PINNICK, RG AF ARMSTRONG, RL XIE, JG RUEKGAUER, TE GU, J PINNICK, RG TI EFFECTS OF SUBMICROMETER-SIZED PARTICLES ON MICRODROPLET LASING SO OPTICS LETTERS LA English DT Article ID MORPHOLOGY-DEPENDENT RESONANCES; STIMULATED RAMAN-SCATTERING; ENHANCED ENERGY-TRANSFER; AEROSOL-PARTICLE; LASER-EMISSION; DROPLETS; TIME AB We report the threshold emission characteristics of lasing from microdroplets that consist of Rhodamine 6G dye in an ethanol solution that contains undoped polystyrene latex spheres. The addition of latex particles to the droplets suppresses lasing. Our findings indicate that, for a fixed Rhodamine 6G concentration and fixed pump intensity, lasing ceases when a certain total threshold latex particle surface area is reached in the droplet, independent of latex particle size. A possible explanation for these findings is the Forster-assisted annihilation of Rhodamine 6G dye lasing levels, facilitated by the adsorption of dye molecules on the surfaces C1 ATMOSPHER SCI LAB,WHITE SANDS MISSILE RANGE,NM 88002. RP ARMSTRONG, RL (reprint author), NEW MEXICO STATE UNIV,DEPT PHYS,LAS CRUCES,NM 88003, USA. NR 17 TC 49 Z9 49 U1 1 U2 6 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 SN 0146-9592 J9 OPT LETT JI Opt. Lett. PD JAN 15 PY 1993 VL 18 IS 2 BP 119 EP 121 DI 10.1364/OL.18.000119 PG 3 WC Optics SC Optics GA KG085 UT WOS:A1993KG08500012 PM 19802057 ER PT J AU BRYANT, GW AF BRYANT, GW TI EXCITON COHERENCE IN SYMMETRICAL COUPLED QUANTUM-WELLS AND DOTS SO PHYSICAL REVIEW B LA English DT Note ID ELECTRIC-FIELDS AB I calculate exciton states of laterally confined, symmetric, double-quantum-well structures in electric fields to study interwell tunneling and electron-bole Coulomb correlation effects. When correlation is dominant, the zero-field exciton ground state is a coherent state of direct excitons in both wells with enhanced oscillator strength. For increasing field, the ground state becomes direct in a single well and then indirect, and exciton peaks in the absorption spectra evolve asymmetrically. RP BRYANT, GW (reprint author), USA,RES LAB,MICROPHOTON DEVICES BRANCH,ADELPHI,MD 20783, USA. NR 13 TC 46 Z9 46 U1 0 U2 1 PU AMERICAN PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0163-1829 J9 PHYS REV B JI Phys. Rev. B PD JAN 15 PY 1993 VL 47 IS 3 BP 1683 EP 1686 DI 10.1103/PhysRevB.47.1683 PG 4 WC Physics, Condensed Matter SC Physics GA KJ518 UT WOS:A1993KJ51800078 ER PT J AU VERMA, A HIRSCH, DJ GLATT, CE RONNETT, GV SNYDER, SH AF VERMA, A HIRSCH, DJ GLATT, CE RONNETT, GV SNYDER, SH TI CARBON-MONOXIDE - A PUTATIVE NEURAL MESSENGER SO SCIENCE LA English DT Article ID NITRIC-OXIDE SYNTHESIS; HEME OXYGENASE; RAT-BRAIN; GUANYLATE-CYCLASE; SMOOTH-MUSCLE; ACTIVATION; RELAXATION; MECHANISM; RNA; VASODILATION AB Carbon monoxide, an activator of guanylyl cyclase, is formed by the action of the enzyme heme oxygenase. By in situ hybridization in brain slices, discrete neuronal localization of messenger RNA for the constitutive form of heme oxygenase throughout the brain has been demonstrated. This localization is essentially the same as that for soluble guanylyl cyclase messenger RNA, In primary cultures of olfactory neurons, zinc protoporphyrin-9, a potent selective inhibitor of heme oxygenase, depletes endogenous guanosine 3',5'-monophosphate (cGMP). Thus, carbon monoxide, like nitric oxide, may be a physiologic regulator of cGMP. These findings, together with the neuronal localizations of heme oxygenase, suggest that carbon monoxide may function as a neurotransmitter. C1 JOHNS HOPKINS UNIV,SCH MED,DEPT NEUROSCI,BALTIMORE,MD 21205. WALTER REED ARMY MED CTR,DEPT NEUROL,WASHINGTON,DC 20307. JOHNS HOPKINS UNIV,SCH MED,DEPT PHARMACOL & MOLEC SCI,BALTIMORE,MD 21205. JOHNS HOPKINS UNIV,SCH MED,DEPT PSYCHIAT,BALTIMORE,MD 21205. JOHNS HOPKINS UNIV,SCH MED,DEPT NEUROL,BALTIMORE,MD 21205. FU NIDA NIH HHS [DA00266]; NIMH NIH HHS [MH18501]; NINDS NIH HHS [NS02131] NR 43 TC 1187 Z9 1235 U1 0 U2 34 PU AMER ASSOC ADVANCEMENT SCIENCE PI WASHINGTON PA 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 SN 0036-8075 J9 SCIENCE JI Science PD JAN 15 PY 1993 VL 259 IS 5093 BP 381 EP 384 DI 10.1126/science.7678352 PG 4 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA KG624 UT WOS:A1993KG62400038 PM 7678352 ER PT J AU BURCH, HB NAGY, EV KAIN, KC LANAR, DE CARR, FE WARTOFSKY, L BURMAN, KD AF BURCH, HB NAGY, EV KAIN, KC LANAR, DE CARR, FE WARTOFSKY, L BURMAN, KD TI EXPRESSION POLYMERASE CHAIN-REACTION FOR THE INVITRO SYNTHESIS AND EPITOPE MAPPING OF AUTOANTIGEN - APPLICATION TO THE HUMAN THYROTROPIN RECEPTOR SO JOURNAL OF IMMUNOLOGICAL METHODS LA English DT Article DE EPITOPE FOR MAPPING HUMAN THYROTROPIN RECEPTOR; AUTOIMMUNITY; AUTOANTIGEN ID TSH RECEPTOR; CLONING; BINDING; PROTEIN; IDENTIFICATION; ANTIBODIES; PEPTIDES; CDNA AB The clinical applicability of a newly described polymerase chain reaction directed protein expression system was assessed for the in vitro synthesis and partial epitope mapping of large radiolabeled human thyrotropin receptor (hTSH-R) protein segments. PCR amplification of targeted regions within the hTSH-R cDNA followed by in vitro transcription and translation permitted rapid synthesis of protein segments ranging in size from 18 to 62 kDa. Initial epitope mapping was directed at a 52 amino acid segment unique to the hTSH-R compared to otherwise homologous glycoprotein hormone receptors. Sera from Graves' disease patients known to have autoantibodies against the hTSH-R were used to immunoprecipitate two protein fragments differing only by the presence of the unique region in the larger fragment (E5) but not in the smaller fragment (E4). Dense precipitation bands were obtained using Graves' sera to immunoprecipitate E5 whereas little or no specific immunoprecipitation of E4 occurred. Normal sera gave only weak immunoprecipitation bands of E5. The technique provides significant advantages over conventional cloning methods and should have general applicability in the study of other protein targets of autoimmune disease. C1 WALTER REED ARMY MED CTR,DEPT MED,KYLE METAB UNIT,ENDOCRINE METAB SERV,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,WALTER REED ARMY INST RES,DEPT IMMUNOL,WASHINGTON,DC 20307. RP BURCH, HB (reprint author), WALTER REED ARMY MED CTR,SCH MED,KYLE METAB SERV,ENDOCRINE METAB SERV,WASHINGTON,DC 20307, USA. RI Lanar, David/B-3560-2011 NR 19 TC 7 Z9 7 U1 0 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0022-1759 J9 J IMMUNOL METHODS JI J. Immunol. Methods PD JAN 14 PY 1993 VL 158 IS 1 BP 123 EP 130 DI 10.1016/0022-1759(93)90264-8 PG 8 WC Biochemical Research Methods; Immunology SC Biochemistry & Molecular Biology; Immunology GA KJ742 UT WOS:A1993KJ74200013 PM 7679129 ER PT J AU BROADHURST, LE ERICKSON, RL KELLEY, PW AF BROADHURST, LE ERICKSON, RL KELLEY, PW TI DECREASES IN INVASIVE HAEMOPHILUS-INFLUENZAE DISEASES IN UNITED-STATES-ARMY CHILDREN, 1984 THROUGH 1991 SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article ID B DISEASE; CONJUGATE VACCINE; EPIDEMIOLOGY; EFFICACY; MENINGITIS; INFECTIONS; POPULATION; POLYSACCHARIDE; COUNTY; YOUNG AB Objective.-To document trends in the incidence of invasive Haemophilus influenzae diseases in young children of US Army active duty soldiers following the publication of H influenzae type b immunization recommendations for young children between 1985 and 1990. Design.-A population-based surveillance of hospital discharge diagnoses for H influenzae invasive diseases. Setting.-Military and civilian medical treatment facilities around the world. Patients.-There was a mean population of nearly 200 000 US Army health care beneficiaries younger than 5 years of age each year of the study. Outcome Measures.-Annual total and age-specific incidences of the six most common H influenzae invasive diseases in this population (meningitis, epiglottitis, septicemia, pneumonia, cellulitis, and septic arthritis). Results.-The annual number of cases of H influenzae invasive diseases decreased from a high of 188 in 1986 to 43 in 1991. The incidence in the age group at highest risk for H influenzae disease, those 6 to 11 months of age, decreased from 355 per 100 000 children in 1986 to 116 per 100 000 in 1991 (P<.0001, chi2 for trend). The incidence for H influenzae meningitis declined from 59 per 100 000 children in 1986 to 6 per 100 000 in 1991 (P<.0001, chi2 for trend). Conclusions.-The decrease in H influenzae invasive diseases closely follows the dates of H influenzae type b vaccine licensure for use in progressively younger age groups. Some age groups, however, experienced a decline in disease rates even before becoming eligible for vaccination. C1 WALTER REED ARMY INST RES,DIV PREVENT MED,DEPT ADV PREVENT MED STUDIES,WASHINGTON,DC 20307. NR 39 TC 86 Z9 86 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD JAN 13 PY 1993 VL 269 IS 2 BP 227 EP 231 DI 10.1001/jama.269.2.227 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA KF405 UT WOS:A1993KF40500028 PM 8417240 ER PT J AU BAN, VS RODEFELD, D FLEMISH, JR JONES, KA AF BAN, VS RODEFELD, D FLEMISH, JR JONES, KA TI HIGH-RATE EPITAXIAL-GROWTH OF INP BY MERGED HYDRIDE ORGANOMETALLIC VAPOR-PHASE EPITAXY IN A HOT-WALL REACTOR SO APPLIED PHYSICS LETTERS LA English DT Article ID III-V COMPOUNDS; VPE AB A new method which combines features of organometallic vapor phase epitaxy (VPE) with hydride VPE has been demonstrated for the epitaxial growth of InP. In this method trimethylindium is coinjected with HCI into a hot-wall reactor to form volatite InCl, and PH3 is used as the phosphorus source. Layers of InP were grown at approximately 8 mum/h with excellent morphology and good electrical properties. Hall measurements at 77 K show background n-type conductivity with n = 7 x 10(15)/cm3 and mu = 34 000 cm2/V S. This technique should be capable of growing ternary and quaternary heterostructures with thin layers and abrupt junctions. C1 USA,ELECTR TECHNOL & DEVICES LAB,FT MONMOUTH,NJ 07703. RP BAN, VS (reprint author), EPITAXX INC,PRINCETON,NJ 08540, USA. NR 6 TC 3 Z9 3 U1 1 U2 1 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0003-6951 J9 APPL PHYS LETT JI Appl. Phys. Lett. PD JAN 11 PY 1993 VL 62 IS 2 BP 160 EP 162 DI 10.1063/1.109357 PG 3 WC Physics, Applied SC Physics GA KF689 UT WOS:A1993KF68900017 ER PT J AU WONG, NCW CARR, FE AF WONG, NCW CARR, FE TI MEMBERS OF THE THYROID STEROID-RECEPTOR SUPERFAMILY THAT REGULATE APOLIPOPROTEIN A1 GENE-EXPRESSION SO JOURNAL OF CELLULAR BIOCHEMISTRY LA English DT Meeting Abstract C1 UNIV CALGARY,DEPT MED,CALGARY T2N 1N4,ALBERTA,CANADA. WALTER REED ARMY MED CTR,KYLE METAB UNIT,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0730-2312 J9 J CELL BIOCHEM JI J. Cell. Biochem. PD JAN 9 PY 1993 SU 17A BP 98 EP 98 PG 1 WC Biochemistry & Molecular Biology; Cell Biology SC Biochemistry & Molecular Biology; Cell Biology GA KN464 UT WOS:A1993KN46400339 ER PT J AU CHIANG, PK DAVE, JR NICHOLSON, DE RHODES, C YAMADA, Y ZENG, GC AF CHIANG, PK DAVE, JR NICHOLSON, DE RHODES, C YAMADA, Y ZENG, GC TI INDUCTION OF DIFFERENTIATION OF 3T3-L1 FIBROBLASTS TO ADIPOCYTES BY 3-DEAZAADENOSINE OR INSULIN REQUIRES C-FOS PROTOONCOGENE SO JOURNAL OF CELLULAR BIOCHEMISTRY LA English DT Meeting Abstract C1 WALTER REED ARMY MED CTR,WASHINGTON,DC 20307. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NIDR,BETHESDA,MD 20892. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0730-2312 J9 J CELL BIOCHEM JI J. Cell. Biochem. PD JAN 9 PY 1993 SU 17A BP 154 EP 154 PG 1 WC Biochemistry & Molecular Biology; Cell Biology SC Biochemistry & Molecular Biology; Cell Biology GA KN464 UT WOS:A1993KN46400563 ER PT J AU MIDDLEBROOK, JL LEATHERMAN, DL AF MIDDLEBROOK, JL LEATHERMAN, DL TI PRESYNAPTIC NEUROTOXINS AS PROBES FOR PHOSPHOPROTEIN REGULATION OF ACETYLCHOLINE-RELEASE FROM MAMMALIAN SYNAPTOSOMES SO JOURNAL OF CELLULAR BIOCHEMISTRY LA English DT Meeting Abstract C1 USA,MED RES INST INFECT DIS,FREDERICK,MD 21701. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0730-2312 J9 J CELL BIOCHEM JI J. Cell. Biochem. PD JAN 9 PY 1993 SU 17A BP 288 EP 288 PG 1 WC Biochemistry & Molecular Biology; Cell Biology SC Biochemistry & Molecular Biology; Cell Biology GA KN464 UT WOS:A1993KN46401076 ER PT J AU HA, MJ KANG, WK BANG, YJ JENSEN, RT FANG, WG SHENKER, A SPIEGEL, AM PARK, DJ KOENIG, ML PIRNIA, F MYERS, CE GOLDSMITH, PK NIKLINSKI, WT TREPEL, JB AF HA, MJ KANG, WK BANG, YJ JENSEN, RT FANG, WG SHENKER, A SPIEGEL, AM PARK, DJ KOENIG, ML PIRNIA, F MYERS, CE GOLDSMITH, PK NIKLINSKI, WT TREPEL, JB TI UNCOUPLING OF PURINERGIC RECEPTORS FROM PHOSPHOLIPASE-C IS ASSOCIATED WITH LOSS OF GROWTH-REGULATION IN A PROSTATE CARCINOMA CELL-LINE SO JOURNAL OF CELLULAR BIOCHEMISTRY LA English DT Meeting Abstract C1 NCI,CLIN PHARMACOL BRANCH,BETHESDA,MD 20892. NIDDKS,DIGEST DIS BRANCH,BETHESDA,MD 20892. NIDDKS,MOLEC PATHOPHYSIOL BRANCH,BETHESDA,MD 20892. NHLBI,BIOCHEM LAB,BETHESDA,MD 20892. WALTER REED ARMY INST RES,INST MED NEUROSCI,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 1 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0730-2312 J9 J CELL BIOCHEM JI J. Cell. Biochem. PD JAN 9 PY 1993 SU 17A BP 317 EP 317 PG 1 WC Biochemistry & Molecular Biology; Cell Biology SC Biochemistry & Molecular Biology; Cell Biology GA KN464 UT WOS:A1993KN46401195 ER PT J AU GERBER, GS THOMPSON, IM THISTED, R CHODAK, GW AF GERBER, GS THOMPSON, IM THISTED, R CHODAK, GW TI DISEASE-SPECIFIC SURVIVAL FOLLOWING ROUTINE PROSTATE-CANCER SCREENING BY DIGITAL RECTAL EXAMINATION SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article ID ADENOCARCINOMA; DIAGNOSIS; ANTIGEN AB Objective.-To assess prostate cancer mortality in men undergoing routine screening by routine digital rectal examination. Design.-Cohort study with a median follow-up period of 75 months. Setting.-Population consisted of volunteers at a university clinic and men in an institutional health maintenance clinic. Patients.-Fifty-six men with a mean age of 65 years (range, 52 to 79 years) diagnosed with prostate cancer. Interventions.-Patients treated initially by observation, external or interstitial radiotherapy, radical prostatectomy, hormone therapy, or combination. Main Outcome Measures.-Kaplan-Meier analysis of time to local progression, distant metastases, death from all causes, and death from prostate cancer. Mantel-Haenszel log-rank statistic was used to compare outcome in men diagnosed on initial examination with those diagnosed on subsequent examinations. Results.-Clinically localized prostate cancer was diagnosed in 73% during an initial examination and in 33% (6/18) during subsequent examinations. Five- and 10-year disease-specific survival was 97% and 86%, respectively, for men diagnosed during the first rectal examination compared with only 81% and 57%, respectively, for men diagnosed on subsequent rectal examinations (P=.02). Conclusion.-Routine screening for prostate cancer by annual digital rectal examination alone may be insufficiently frequent and/or sensitive to prevent significant mortality from this disease. C1 UNIV CHICAGO HOSP & CLIN,DEPT SURG,DIV UROL,CHICAGO,IL 60637. UNIV CHICAGO HOSP & CLIN,DEPT STAT,CHICAGO,IL 60637. UNIV CHICAGO HOSP & CLIN,DEPT ANESTHESIA & CRIT CARE,CHICAGO,IL 60637. BROOKE ARMY MED CTR,DEPT SURG,UROL SERV,FT SAM HOUSTON,TX 78234. RI Thisted, Ronald/B-1985-2008 NR 16 TC 65 Z9 66 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD JAN 6 PY 1993 VL 269 IS 1 BP 61 EP 64 DI 10.1001/jama.269.1.61 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA KF026 UT WOS:A1993KF02600028 PM 8416407 ER PT B AU PENNISE, CA BOESCH, HE GOETZ, G MCKITTERICK, JB AF PENNISE, CA BOESCH, HE GOETZ, G MCKITTERICK, JB GP IEEE TI RADIATION EFFECTS IN BESOI STRUCTURES WITH DIFFERENT INSULATING LAYERS SO 1993 IEEE INTERNATIONAL SOI CONFERENCE PROCEEDINGS LA English DT Proceedings Paper CT 1993 IEEE International SOI Conference CY OCT 05-07, 1993 CL PALM SPRINGS, CA SP IEEE, ELECTRON DEVICES SOC C1 USA,RES LAB,ADELPHI,MD 20783. NR 0 TC 0 Z9 0 U1 1 U2 1 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1346-1 PY 1993 BP 30 EP 31 PG 2 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA BA38C UT WOS:A1993BA38C00010 ER PT J AU BYRD, JL HUMPHREY, J AF BYRD, JL HUMPHREY, J BE Wacks, ME TI DEPARTMENT-OF-DEFENSE DEPARTMENT-OF-ENERGY (DOD DOE) RESEARCH-AND-DEVELOPMENT (RESEARCH-AND-DEVELOPMENT) OF INCINERATION TECHNIQUES FOR DEMILITARIZATION SO 1993 INCINERATION CONFERENCE: PROCEEDINGS: THERMAL TREATMENT OF RADIOACTIVE, HAZARDOUS CHEMICAL, MIXED, ENERGETIC, CHEMICAL WEAPON, AND MEDICAL WASTES LA English DT Proceedings Paper CT 1993 Incineration Conference: Thermal Treatment of Radioactive, Hazardous Chemical, Mixed, Energetic, Chemical Weapon, and Medical Wastes CY MAY 03-07, 1993 CL KNOXVILLE, TN SP UNIV CALIF IRVINE, AMER INST CHEM ENGINEERS, AIR & WASTE MANAGEMENT ASSOC, AMER NUCL SOC, AMER SOC MECH ENGINEERS, COALIT RESPONSIBLE WASTE INCINERAT, HLTH PHYS SOC, US DOE, US EPA C1 USA,DEF AMMUNIT CTR & SCH,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU 1993 INCINERATION CONFERENCE PI IRVINE PA C/O CHARLOTTE BAKER, UNIV CALIFORNIA IRVINE, IRVINE, CA 92717 PY 1993 BP 621 EP 624 PG 4 WC Engineering, Environmental SC Engineering GA BA72Z UT WOS:A1993BA72Z00112 ER PT J AU JOHNSON, MB BACON, DP AF JOHNSON, MB BACON, DP BE Wacks, ME TI DEVELOPING A TESTING SYSTEM FOR CHARACTERIZING EMISSIONS PRODUCED DURING OPEN BURNING OPEN DETONATION OF ENERGETIC MATERIALS SO 1993 INCINERATION CONFERENCE: PROCEEDINGS: THERMAL TREATMENT OF RADIOACTIVE, HAZARDOUS CHEMICAL, MIXED, ENERGETIC, CHEMICAL WEAPON, AND MEDICAL WASTES LA English DT Proceedings Paper CT 1993 Incineration Conference: Thermal Treatment of Radioactive, Hazardous Chemical, Mixed, Energetic, Chemical Weapon, and Medical Wastes CY MAY 03-07, 1993 CL KNOXVILLE, TN SP UNIV CALIF IRVINE, AMER INST CHEM ENGINEERS, AIR & WASTE MANAGEMENT ASSOC, AMER NUCL SOC, AMER SOC MECH ENGINEERS, COALIT RESPONSIBLE WASTE INCINERAT, HLTH PHYS SOC, US DOE, US EPA C1 USA,DUGWAY PROVING GROUND,DUGWAY PROVING GROUND,UT. NR 0 TC 0 Z9 0 U1 0 U2 0 PU 1993 INCINERATION CONFERENCE PI IRVINE PA C/O CHARLOTTE BAKER, UNIV CALIFORNIA IRVINE, IRVINE, CA 92717 PY 1993 BP 631 EP 635 PG 5 WC Engineering, Environmental SC Engineering GA BA72Z UT WOS:A1993BA72Z00114 ER PT J AU ANSELL, E AF ANSELL, E BE Wacks, ME TI DEPARTMENT-OF-DEFENSE DEPARTMENT-OF-ENERGY (DOD/DOE) RESEARCH-AND-DEVELOPMENT (RESEARCH-AND-DEVELOPMENT) OF TECHNIQUES FOR DEMILITARIZATION SO 1993 INCINERATION CONFERENCE: PROCEEDINGS: THERMAL TREATMENT OF RADIOACTIVE, HAZARDOUS CHEMICAL, MIXED, ENERGETIC, CHEMICAL WEAPON, AND MEDICAL WASTES LA English DT Proceedings Paper CT 1993 Incineration Conference: Thermal Treatment of Radioactive, Hazardous Chemical, Mixed, Energetic, Chemical Weapon, and Medical Wastes CY MAY 03-07, 1993 CL KNOXVILLE, TN SP UNIV CALIF IRVINE, AMER INST CHEM ENGINEERS, AIR & WASTE MANAGEMENT ASSOC, AMER NUCL SOC, AMER SOC MECH ENGINEERS, COALIT RESPONSIBLE WASTE INCINERAT, HLTH PHYS SOC, US DOE, US EPA C1 USA,CHEM MAT DESTRUCT AGCY,OFF TECHNOL EXCHANGE & TREATY COMPLIANCE,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU 1993 INCINERATION CONFERENCE PI IRVINE PA C/O CHARLOTTE BAKER, UNIV CALIFORNIA IRVINE, IRVINE, CA 92717 PY 1993 BP 637 EP 639 PG 3 WC Engineering, Environmental SC Engineering GA BA72Z UT WOS:A1993BA72Z00115 ER PT J AU SANTOS, JS MARTINEZ, E AF SANTOS, JS MARTINEZ, E BE Wacks, ME TI DESIGN AND INSTALLATION OF A WASTE PROPELLANT AND EXPLOSIVE INCINERATOR SO 1993 INCINERATION CONFERENCE: PROCEEDINGS: THERMAL TREATMENT OF RADIOACTIVE, HAZARDOUS CHEMICAL, MIXED, ENERGETIC, CHEMICAL WEAPON, AND MEDICAL WASTES LA English DT Proceedings Paper CT 1993 Incineration Conference: Thermal Treatment of Radioactive, Hazardous Chemical, Mixed, Energetic, Chemical Weapon, and Medical Wastes CY MAY 03-07, 1993 CL KNOXVILLE, TN SP UNIV CALIF IRVINE, AMER INST CHEM ENGINEERS, AIR & WASTE MANAGEMENT ASSOC, AMER NUCL SOC, AMER SOC MECH ENGINEERS, COALIT RESPONSIBLE WASTE INCINERAT, HLTH PHYS SOC, US DOE, US EPA C1 USA,CTR ARMAMENT RES DEV & ENGN,PICATINNY ARSENAL,NJ 07806. NR 0 TC 0 Z9 0 U1 0 U2 0 PU 1993 INCINERATION CONFERENCE PI IRVINE PA C/O CHARLOTTE BAKER, UNIV CALIFORNIA IRVINE, IRVINE, CA 92717 PY 1993 BP 641 EP 643 PG 3 WC Engineering, Environmental SC Engineering GA BA72Z UT WOS:A1993BA72Z00116 ER PT J AU ONTIVEROS, JL MACRAE, SR AF ONTIVEROS, JL MACRAE, SR BE Wacks, ME TI JOHNSTON ATOLL CHEMICAL-AGENT DISPOSAL SYSTEM (JACADS) - M55 ROCKET DISPOSAL PERFORMANCE SO 1993 INCINERATION CONFERENCE: PROCEEDINGS: THERMAL TREATMENT OF RADIOACTIVE, HAZARDOUS CHEMICAL, MIXED, ENERGETIC, CHEMICAL WEAPON, AND MEDICAL WASTES LA English DT Proceedings Paper CT 1993 Incineration Conference: Thermal Treatment of Radioactive, Hazardous Chemical, Mixed, Energetic, Chemical Weapon, and Medical Wastes CY MAY 03-07, 1993 CL KNOXVILLE, TN SP UNIV CALIF IRVINE, AMER INST CHEM ENGINEERS, AIR & WASTE MANAGEMENT ASSOC, AMER NUCL SOC, AMER SOC MECH ENGINEERS, COALIT RESPONSIBLE WASTE INCINERAT, HLTH PHYS SOC, US DOE, US EPA C1 USA,CMDA,DIV ENGN & OPS,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 0 Z9 0 U1 0 U2 0 PU 1993 INCINERATION CONFERENCE PI IRVINE PA C/O CHARLOTTE BAKER, UNIV CALIFORNIA IRVINE, IRVINE, CA 92717 PY 1993 BP 777 EP 781 PG 5 WC Engineering, Environmental SC Engineering GA BA72Z UT WOS:A1993BA72Z00140 ER PT B AU BROWN, JA AF BROWN, JA BE Sanson, LD TI THE IMPORTANCE OF THE SITE SURVEY IN PLANNING AND IMPLEMENTING AN ELECTRONIC SECURITY SYSTEM SO 1993 INTERNATIONAL CARNAHAN CONFERENCE ON SECURITY TECHNOLOGY : SECURITY TECHNOLOGY LA English DT Proceedings Paper CT 1993 International Carnahan Conference on Security Technology: Security Technology CY OCT 13-15, 1993 CL OTTAWA, CANADA SP IEEE, LEXINGTON SECT, IEEE, AEROSP & ELECTR SYST SOC, G LEVETT & ASSOC, IEEE, OTTAWA SECT, GEORGIA TECH RES INST, CHUNG SHAN INST SCI & TECHNOLOGY, TAIPEI, NATL CHIAO TUNG UNIV, TAIPEI C1 USA,CORPS ENGINEERS,INTRUS DETECT SYST CTR EXPERTISE,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1479-4 PY 1993 BP 58 EP 59 PG 2 WC Engineering, Electrical & Electronic SC Engineering GA BA51Q UT WOS:A1993BA51Q00013 ER PT B AU CHIANG, D FISHBEIN, W SHEPPARD, D AF CHIANG, D FISHBEIN, W SHEPPARD, D BE Sanson, LD TI ACOUSTIC AIRCRAFT DETECTION SENSOR SO 1993 INTERNATIONAL CARNAHAN CONFERENCE ON SECURITY TECHNOLOGY : SECURITY TECHNOLOGY LA English DT Proceedings Paper CT 1993 International Carnahan Conference on Security Technology: Security Technology CY OCT 13-15, 1993 CL OTTAWA, CANADA SP IEEE, LEXINGTON SECT, IEEE, AEROSP & ELECTR SYST SOC, G LEVETT & ASSOC, IEEE, OTTAWA SECT, GEORGIA TECH RES INST, CHUNG SHAN INST SCI & TECHNOLOGY, TAIPEI, NATL CHIAO TUNG UNIV, TAIPEI C1 USA,COMMUN & ELECTR COMMAND,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1479-4 PY 1993 BP 127 EP 133 PG 7 WC Engineering, Electrical & Electronic SC Engineering GA BA51Q UT WOS:A1993BA51Q00025 ER PT B AU COLE, JL VALENTINE, P AF COLE, JL VALENTINE, P BE Evans, GW Mollaghasemi, M Russell, EC Biles, WE TI JOINT DATA-BASE ELEMENTS FOR MODELING AND SIMULATION SO 1993 WINTER SIMULATION CONFERENCE PROCEEDINGS LA English DT Proceedings Paper CT 1993 Winter Simulation Conference CY DEC 12-15, 1993 CL LOS ANGELES, CA SP AMER STAT ASSOC, ASSOC COMP MACHINERY, SPECIAL INTEREST GRP SIMULAT, IEEE, COMP SOC, IEEE, SYST MAN & CYBERNET SOC, INST IND ENGINEERS, NIST, OPERAT RES SOC AMER, INST MANAGEMENT SCI, COLL SIMULAT, SOC COMP SIMULAT INT C1 USA,ELECTROMAGNET ENVIRONM TEST FACIL,FT HUACHUCA,AZ 85613. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1381-X PY 1993 BP 971 EP 976 PG 6 WC Computer Science, Interdisciplinary Applications; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BA27E UT WOS:A1993BA27E00132 ER PT B AU JOHNSON, WR MASTAGLIO, TW PETERSON, PD AF JOHNSON, WR MASTAGLIO, TW PETERSON, PD BE Evans, GW Mollaghasemi, M Russell, EC Biles, WE TI THE CLOSE COMBAT TACTICAL TRAINER PROGRAM SO 1993 WINTER SIMULATION CONFERENCE PROCEEDINGS LA English DT Proceedings Paper CT 1993 Winter Simulation Conference CY DEC 12-15, 1993 CL LOS ANGELES, CA SP AMER STAT ASSOC, ASSOC COMP MACHINERY, SPECIAL INTEREST GRP SIMULAT, IEEE, COMP SOC, IEEE, SYST MAN & CYBERNET SOC, INST IND ENGINEERS, NIST, OPERAT RES SOC AMER, INST MANAGEMENT SCI, COLL SIMULAT, SOC COMP SIMULAT INT C1 USA,STRICOM,CATT,PM,ORLANDO,FL 32826. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1381-X PY 1993 BP 1021 EP 1029 PG 9 WC Computer Science, Interdisciplinary Applications; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BA27E UT WOS:A1993BA27E00139 ER PT B AU JOHNSON, LH CROCKER, CM AF JOHNSON, LH CROCKER, CM BE Evans, GW Mollaghasemi, M Russell, EC Biles, WE TI COST-EFFECTIVE WEAPON SYSTEM-DEVELOPMENT THROUGH INTEGRATED MODELING AND HARDWARE TESTING SO 1993 WINTER SIMULATION CONFERENCE PROCEEDINGS LA English DT Proceedings Paper CT 1993 Winter Simulation Conference CY DEC 12-15, 1993 CL LOS ANGELES, CA SP AMER STAT ASSOC, ASSOC COMP MACHINERY, SPECIAL INTEREST GRP SIMULAT, IEEE, COMP SOC, IEEE, SYST MAN & CYBERNET SOC, INST IND ENGINEERS, NIST, OPERAT RES SOC AMER, INST MANAGEMENT SCI, COLL SIMULAT, SOC COMP SIMULAT INT C1 USA,TEST & EVALUAT COMMAND,REDSTONE TECH TEST CTR,REDSTONE ARSENAL,AL 35898. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1381-X PY 1993 BP 1365 EP 1367 PG 3 WC Computer Science, Interdisciplinary Applications; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BA27E UT WOS:A1993BA27E00191 ER PT B AU KROUTIL, RT COMBS, RJ KNAPP, RB SMALL, GW AF KROUTIL, RT COMBS, RJ KNAPP, RB SMALL, GW BE Bertie, JE Wieser, H TI REMOTE INFRARED VAPOR DETECTION OF VOLATILE ORGANIC-COMPOUNDS SO 9TH INTERNATIONAL CONFERENCE ON FOURIER TRANSFORM SPECTROSCOPY SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT 9th International Conference on Fourier Transform Spectroscopy CY AUG 23-27, 1993 CL CALGARY, CANADA SP COBLENTZ SOC, UNIV CALGARY, DEPT CHEM, SPECTROSCOPY SOC CANADA C1 USA,EDGEWOOD RES DEV & ENGN CTR,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 6 Z9 6 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1360-7 J9 P SOC PHOTO-OPT INS PY 1993 VL 2089 BP 24 EP 31 PG 8 WC Spectroscopy SC Spectroscopy GA BZ89P UT WOS:A1993BZ89P00004 ER PT B AU MORRIS, JB MCNESBY, KL AF MORRIS, JB MCNESBY, KL BE Bertie, JE Wieser, H TI COMPARATIVE INFRARED AND RAMAN-SPECTROSCOPY OF COMPOUNDS IN HIGH-PRESSURE MEDIA SO 9TH INTERNATIONAL CONFERENCE ON FOURIER TRANSFORM SPECTROSCOPY SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT 9th International Conference on Fourier Transform Spectroscopy CY AUG 23-27, 1993 CL CALGARY, CANADA SP COBLENTZ SOC, UNIV CALGARY, DEPT CHEM, SPECTROSCOPY SOC CANADA C1 USA,RES LAB,AMSRL WT PC,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 1 Z9 1 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1360-7 J9 P SOC PHOTO-OPT INS PY 1993 VL 2089 BP 272 EP 273 PG 2 WC Spectroscopy SC Spectroscopy GA BZ89P UT WOS:A1993BZ89P00099 ER PT B AU MCNESBY, KL DANIEL, RG FIFER, RA AF MCNESBY, KL DANIEL, RG FIFER, RA BE Bertie, JE Wieser, H TI 3-DIMENSIONAL INFRARED IMAGING OF LOW-PRESSURE FLAMES SO 9TH INTERNATIONAL CONFERENCE ON FOURIER TRANSFORM SPECTROSCOPY SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT 9th International Conference on Fourier Transform Spectroscopy CY AUG 23-27, 1993 CL CALGARY, CANADA SP COBLENTZ SOC, UNIV CALGARY, DEPT CHEM, SPECTROSCOPY SOC CANADA C1 USA,RES LAB,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1360-7 J9 P SOC PHOTO-OPT INS PY 1993 VL 2089 BP 436 EP 437 PG 2 WC Spectroscopy SC Spectroscopy GA BZ89P UT WOS:A1993BZ89P00181 ER PT B AU MCNESBY, KL WOLFE, JE MORRIS, JB FIFER, RA AF MCNESBY, KL WOLFE, JE MORRIS, JB FIFER, RA BE Bertie, JE Wieser, H TI FT-RAMAN SPECTROSCOPY OF SOME ENERGETIC MATERIALS AND PROPELLANT FORMULATIONS SO 9TH INTERNATIONAL CONFERENCE ON FOURIER TRANSFORM SPECTROSCOPY SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT 9th International Conference on Fourier Transform Spectroscopy CY AUG 23-27, 1993 CL CALGARY, CANADA SP COBLENTZ SOC, UNIV CALGARY, DEPT CHEM, SPECTROSCOPY SOC CANADA C1 USA,RES LAB,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1360-7 J9 P SOC PHOTO-OPT INS PY 1993 VL 2089 BP 550 EP 551 PG 2 WC Spectroscopy SC Spectroscopy GA BZ89P UT WOS:A1993BZ89P00238 ER PT J AU KLAYMAN, DL AF KLAYMAN, DL TI ARTEMISIA-ANNUA - FROM WEED TO RESPECTABLE ANTIMALARIAL PLANT SO ACS SYMPOSIUM SERIES LA English DT Review ID QINGHAOSU ARTEMISININ; STEREOSPECIFIC SYNTHESIS; DIHYDROARTEMISININ DERIVATIVES; STEREOSELECTIVE SYNTHESIS; DECOMPOSITION PRODUCTS; TISSUE-CULTURES; ACID; ARTEANNUIN; CONVERSION; DRUGS AB In the early 1970's, a potent and essentially non-toxic antimalarial agent was isolated from qing hao (Artemisia annua), a plant used in Chinese folk medicine for some 20 centuries. The active compound, artemisinin (qinghaosu), is a sesquiterpene lactone bearing an unusual endoperoxide group that is essential for its activity. Artemisinin is effective against drug-sensitive and -resistant Plasmodium falciparum and P. vivax. Oil-soluble derivatives of artemisinin, such as artemether and arteether, and water-soluble derivatives, such as sodium artesunate and sodium artelinate, have increased potency and allow fewer recrudescences. The latter two have special application for the treatment of potentially fatal cerebral malaria. Recent animal studies suggest that the artemisinin class of compounds may be effective when administered transdermally. RP KLAYMAN, DL (reprint author), WALTER REED ARMY INST RES,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307, USA. NR 136 TC 38 Z9 39 U1 1 U2 7 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0097-6156 J9 ACS SYM SER PY 1993 VL 534 BP 242 EP 255 PG 14 WC Chemistry, Multidisciplinary SC Chemistry GA LX112 UT WOS:A1993LX11200017 ER PT J AU VALANIS, KC PETERS, JF GILL, J AF VALANIS, KC PETERS, JF GILL, J TI CONFIGURATIONAL ENTROPY, NON-ASSOCIATIVITY AND UNIQUENESS IN GRANULAR MEDIA SO ACTA MECHANICA LA English DT Article ID PLASTICITY AB It has long been recognized that fabric, i.e., the grain configuration in a domain, plays a significant role in the constitutive response of granular media. Here we establish that this effect has bearing on the suitability of non-associative plasticity laws that describe the observed deviation of the plastic strain rate, from the normal to the yield surface. It is known that when non-associated plasticity laws are used, uniqueness of the solution of the initial value problem cannot be proved. Here it is shown that the introduction of configurational entropy and temperature into the theory, gives rise to a thermodynamic framework, specifically a thermoplastic potential, with respect to which the plasticity law is associative. However, the inelastic strain is the sum of a plastic and a configurational strain. While the plastic strain rate is still normal to the potential (yield) surface, the inelastic strain rate, which is what is measured in the laboratory, is not. It is further shown that despite the non-normality of the inelastic strain rate to the plastic potential surface, the solution of the coupled initial value - configurational diffusion problem is unique. In the process of development of the underlying configurational thermodynamics, the concept of configurational flux is introduced and a time indifferent configurational diffusion law is inferred on the basis of uniqueness requirements. Thus the foundation is laid for the mode of propagation of chaos in granular media. C1 USA,WATERWAYS EXPT STN,VICKSBURG,MS 39180. RP VALANIS, KC (reprint author), ENDOCHRON INC,8605 LAKECREST COURT,VANCOUVER,WA 98665, USA. NR 22 TC 4 Z9 4 U1 0 U2 0 PU SPRINGER-VERLAG WIEN PI VIENNA PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 VIENNA, AUSTRIA SN 0001-5970 J9 ACTA MECH JI Acta Mech. PY 1993 VL 100 IS 1-2 BP 79 EP 93 DI 10.1007/BF01176863 PG 15 WC Mechanics SC Mechanics GA LN796 UT WOS:A1993LN79600005 ER PT J AU ZUKAS, WX WENTWORTH, SE SENNETT, MS AF ZUKAS, WX WENTWORTH, SE SENNETT, MS BE Boerio, FJ TI KINETICS OF EPOXY AMINE CURE REACTIONS AT ALUMINA SURFACES SO ADHESION SOCIETY PROCEEDINGS OF THE SIXTEENTH ANNUAL MEETING AND THE INTERNATIONAL SYMPOSIUM ON THE INTERPHASE LA English DT Proceedings Paper CT 16th Annual Meeting of the Adhesion-Society/International Symposium on the Interphase CY FEB 21-26, 1993 CL WILLIAMSBURG, VA SP ADHES SOC, USN, OFF NAVAL RES, NATL SCI FDN, USA, ARMY RES OFF, GORDON & BREACH SCI PUBL INC, LOCTITE CORP, DOW CHEM CO, ESSEX SPECIALTY CHEM CO, NATL STARCH & CHEM CO, ALLIED SIGNAL, S C JOHNSON WAX, FORD MOTOR CO, AIR PROD & CHEM CO, AMER VACUUM SOC, APPL SURFACE SCI DIV C1 USA,MAT TECHNOL LAB,POLYMER RES BRANCH,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ADHESION SOCIETY PI BALTIMORE PA MARTIN MARIETTA LABORATORIES 1450 S ROLLING RD, BALTIMORE, MD 21227 PY 1993 BP 187 EP 190 PG 4 WC Engineering, Mechanical; Materials Science, Characterization & Testing; Materials Science, Coatings & Films; Materials Science, Composites; Polymer Science SC Engineering; Materials Science; Polymer Science GA BC38S UT WOS:A1993BC38S00061 ER PT B AU ENNIS, DH PATTY, CE AF ENNIS, DH PATTY, CE BE Chandra, T Dhingra, AK TI ADVANCED STRATEGIC INTERCEPTOR COMPOSITE STRUCTURES SO ADVANCED COMPOSITES '93: INTERNATIONAL CONFERENCE ON ADVANCED COMPOSITE MATERIALS LA English DT Proceedings Paper CT International Conference on Advanced Composite Materials (ICACM) - Advanced Composites 93 CY FEB 15-19, 1993 CL UNIV WOLLONGONG, WOLLONGONG, AUSTRALIA SP MINERALS MET & MAT SOC, PHYS MET COMM HO UNIV WOLLONGONG C1 USA,STRATEG DEF COMMAND,HUNTSVILLE,AL 35807. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MINERALS, METALS & MATERIALS SOC PI WARRENDALE PA 420 COMMONWEALTH DR, WARRENDALE, PA 15086 BN 0-87339-251-5 PY 1993 BP 109 EP 114 PG 6 WC Materials Science, Composites SC Materials Science GA BA47E UT WOS:A1993BA47E00013 ER PT B AU RUPERT, NL BURKINS, MS GOOCH, WA WALZ, MJ LEVOY, NF WASHCHILLA, EP AF RUPERT, NL BURKINS, MS GOOCH, WA WALZ, MJ LEVOY, NF WASHCHILLA, EP BE Chandra, T Dhingra, AK TI DEVELOPMENT OF HIGH-DENSITY CERAMIC COMPOSITES FOR BALLISTIC APPLICATIONS SO ADVANCED COMPOSITES '93: INTERNATIONAL CONFERENCE ON ADVANCED COMPOSITE MATERIALS LA English DT Proceedings Paper CT International Conference on Advanced Composite Materials (ICACM) - Advanced Composites 93 CY FEB 15-19, 1993 CL UNIV WOLLONGONG, WOLLONGONG, AUSTRALIA SP MINERALS MET & MAT SOC, PHYS MET COMM HO UNIV WOLLONGONG C1 USA,RES LAB,AMSRL WT TA,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MINERALS, METALS & MATERIALS SOC PI WARRENDALE PA 420 COMMONWEALTH DR, WARRENDALE, PA 15086 BN 0-87339-251-5 PY 1993 BP 141 EP 146 PG 6 WC Materials Science, Composites SC Materials Science GA BA47E UT WOS:A1993BA47E00018 ER PT B AU OBRIEN, TK AF OBRIEN, TK BE Chandra, T Dhingra, AK TI STACKING-SEQUENCE EFFECT ON LOCAL DELAMINATION ONSET IN FATIGUE SO ADVANCED COMPOSITES '93: INTERNATIONAL CONFERENCE ON ADVANCED COMPOSITE MATERIALS LA English DT Proceedings Paper CT International Conference on Advanced Composite Materials (ICACM) - Advanced Composites 93 CY FEB 15-19, 1993 CL UNIV WOLLONGONG, WOLLONGONG, AUSTRALIA SP MINERALS MET & MAT SOC, PHYS MET COMM HO UNIV WOLLONGONG C1 NASA,LANGLEY RES CTR,USA,VEHICLE STRUCT DIRECTORATE,HAMPTON,VA 23681. NR 0 TC 1 Z9 1 U1 0 U2 0 PU MINERALS, METALS & MATERIALS SOC PI WARRENDALE PA 420 COMMONWEALTH DR, WARRENDALE, PA 15086 BN 0-87339-251-5 PY 1993 BP 399 EP 406 PG 8 WC Materials Science, Composites SC Materials Science GA BA47E UT WOS:A1993BA47E00056 ER PT B AU CYTRON, S AF CYTRON, S BE Chandra, T Dhingra, AK TI RECENT ADVANCES IN HIGH-DENSITY TUNGSTEN COMPOSITE PROCESSING SO ADVANCED COMPOSITES '93: INTERNATIONAL CONFERENCE ON ADVANCED COMPOSITE MATERIALS LA English DT Proceedings Paper CT International Conference on Advanced Composite Materials (ICACM) - Advanced Composites 93 CY FEB 15-19, 1993 CL UNIV WOLLONGONG, WOLLONGONG, AUSTRALIA SP MINERALS MET & MAT SOC, PHYS MET COMM HO UNIV WOLLONGONG C1 USA,ARMAMENT RES,CTR DEV & ENGN,DOVER,NJ. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MINERALS, METALS & MATERIALS SOC PI WARRENDALE PA 420 COMMONWEALTH DR, WARRENDALE, PA 15086 BN 0-87339-251-5 PY 1993 BP 973 EP 978 PG 6 WC Materials Science, Composites SC Materials Science GA BA47E UT WOS:A1993BA47E00145 ER PT B AU BAKER, DJ AF BAKER, DJ GP ESD, THE ENGINEERING SOC TI FLIGHT SERVICE EXPERIENCES WITH COMPOSITES SO ADVANCED COMPOSITES TECHNOLOGIES LA English DT Proceedings Paper CT 9th Annual ASM/ESD Advanced Composites Conference CY NOV 08-11, 1993 CL DEARBORN, MI SP ESD, THE ENGN SOC, ASM INT, SOC ADV MAT & PROC ENGN, AMER SOC COMPOSITES, MICHIGAN MAT & PROC INST, EDISON MAT TECHNOL CTR C1 NASA,LANGLEY RES CTR,USA,RES LAB,VEHICLE STRUCT DIRECTORATE,HAMPTON,VA 23665. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ESD-THE ENGINEERING SOCIETY PI DETROIT PA 100 FARNSWORTH AVE, DETROIT, MI 48202 BN 1-56378-014-3 PY 1993 BP 481 EP 505 PG 25 WC Engineering, Manufacturing; Engineering, Mechanical; Materials Science, Composites SC Engineering; Materials Science GA BC87Q UT WOS:A1993BC87Q00035 ER PT B AU STRAFFON, NL FARKAS, AJ AF STRAFFON, NL FARKAS, AJ GP ESD, THE ENGINEERING SOC TI THE NATIONAL AUTOMOTIVE CENTER AT THE UNITED-STATES-ARMY TANK-AUTOMOTIVE RESEARCH, DEVELOPMENT & ENGINEERING CENTER SO ADVANCED COMPOSITES TECHNOLOGIES LA English DT Proceedings Paper CT 9th Annual ASM/ESD Advanced Composites Conference CY NOV 08-11, 1993 CL DEARBORN, MI SP ESD, THE ENGN SOC, ASM INT, SOC ADV MAT & PROC ENGN, AMER SOC COMPOSITES, MICHIGAN MAT & PROC INST, EDISON MAT TECHNOL CTR C1 USA,TACOM,NATL AUTOMOT CTR,WARREN,MI. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ESD-THE ENGINEERING SOCIETY PI DETROIT PA 100 FARNSWORTH AVE, DETROIT, MI 48202 BN 1-56378-014-3 PY 1993 BP 603 EP 608 PG 6 WC Engineering, Manufacturing; Engineering, Mechanical; Materials Science, Composites SC Engineering; Materials Science GA BC87Q UT WOS:A1993BC87Q00045 ER PT S AU CHABOT, KA BRESCIA, JA AF CHABOT, KA BRESCIA, JA BE Trabocco, R Lynch, T TI EVALUATION OF PRIMERS FOR AIRCRAFT REPAIR, VOLUME II SO ADVANCED MATERIALS: EXPANDING THE HORIZONS SE INTERNATIONAL SAMPE TECHNICAL CONFERENCE SERIES LA English DT Proceedings Paper CT 25th International SAMPE Technical Conference on Advanced Materials: Expanding the Horizons CY OCT 26-28, 1993 CL PHILADELPHIA, PA SP SOC ADV MAT & PROC ENGN DE PRIMERS; SILANE; TITANIUM; STEEL C1 USA,CTR ARMAMENT RES DEV & ENGN,PICATINNY ARSENAL,NJ 07806. NR 0 TC 2 Z9 2 U1 0 U2 0 PU SOC ADVANCEMENT MATERIAL & PROCESS ENGINEERING PI COVINA PA 843 W GLENTANA ST, PO BOX 2459, COVINA, CA 91722 SN 0892-2624 BN 0-938994-68-9 J9 INT SAMPE TECH CONF PY 1993 VL 25 BP 200 EP 211 PG 12 WC Materials Science, Multidisciplinary SC Materials Science GA BZ43E UT WOS:A1993BZ43E00019 ER PT S AU CHABOT, KA BONK, RB AF CHABOT, KA BONK, RB BE Trabocco, R Lynch, T TI EVALUATION OF ADHESIVES AND PRIMER SYSTEMS FOR ADHERING CARBON-EPOXY COMPOSITES AND METALS SO ADVANCED MATERIALS: EXPANDING THE HORIZONS SE INTERNATIONAL SAMPE TECHNICAL CONFERENCE SERIES LA English DT Proceedings Paper CT 25th International SAMPE Technical Conference on Advanced Materials: Expanding the Horizons CY OCT 26-28, 1993 CL PHILADELPHIA, PA SP SOC ADV MAT & PROC ENGN DE CARBON EPOXY COMPOSITES; WATER-BORNE PRIMERS; EPOXY ADHESIVES C1 USA,CTR ARMAMENT RES DEV & ENGN,PICATINNY ARSENAL,NJ 07806. NR 0 TC 0 Z9 0 U1 0 U2 1 PU SOC ADVANCEMENT MATERIAL & PROCESS ENGINEERING PI COVINA PA 843 W GLENTANA ST, PO BOX 2459, COVINA, CA 91722 SN 0892-2624 BN 0-938994-68-9 J9 INT SAMPE TECH CONF PY 1993 VL 25 BP 338 EP 352 PG 15 WC Materials Science, Multidisciplinary SC Materials Science GA BZ43E UT WOS:A1993BZ43E00031 ER PT S AU CHABOT, KA BRESCIA, JA AF CHABOT, KA BRESCIA, JA BE Trabocco, R Lynch, T TI IMPROVED BONDING PROCESSES FOR HELICOPTER MAIN ROTOR BLADE EROSION PROTECTION SO ADVANCED MATERIALS: EXPANDING THE HORIZONS SE INTERNATIONAL SAMPE TECHNICAL CONFERENCE SERIES LA English DT Proceedings Paper CT 25th International SAMPE Technical Conference on Advanced Materials: Expanding the Horizons CY OCT 26-28, 1993 CL PHILADELPHIA, PA SP SOC ADV MAT & PROC ENGN DE CORONA DISCHARGE; POLYURETHANE; CONTACT ANGLE C1 USA,CTR ARMAMENT RES DEV & ENGN,PICATINNY ARSENAL,NJ 07806. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC ADVANCEMENT MATERIAL & PROCESS ENGINEERING PI COVINA PA 843 W GLENTANA ST, PO BOX 2459, COVINA, CA 91722 SN 0892-2624 BN 0-938994-68-9 J9 INT SAMPE TECH CONF PY 1993 VL 25 BP 431 EP 443 PG 13 WC Materials Science, Multidisciplinary SC Materials Science GA BZ43E UT WOS:A1993BZ43E00039 ER PT J AU RASDORF, WJ SPAINHOUR, LK PATTON, EM BURNS, BP AF RASDORF, WJ SPAINHOUR, LK PATTON, EM BURNS, BP TI CDI - LINKING MATERIAL PROPERTY DATABASES TO ANALYSIS CODES SO ADVANCES IN ENGINEERING SOFTWARE LA English DT Article AB Integration among programs designed to solve complex engineering problems is often lacking, and this is particularly a problem in the area of thick composite materials analysis and design where a large volume of input must be provided. Another problem is the lack of an archival repository in which to store input information in a generic format. To address these problems, we have developed a prototype of a finite element material property reprocessing system, called the composites data-base interface (CDI). In this computer-aided analysis system, a materials database is integrated with several software components, including commercially available finite element analysis (FEA) programs and preprocessors, and tools for manipulating and using composite materials data, resulting in the transfer of two- and three-dimensional composite materials property data into an FEA program. This paper presents the capabilities of this system, discusses the overall system integration through R : BASE, and provides a civil engineering application involving the design of a large cylindrical tank to illustrate the execution of the CDI system's various components. The paper ends by discussing the current status of this computer-aided analysis system. C1 N CAROLINA STATE UNIV,DEPT CIVIL ENGN,RALEIGH,NC 27695. USA,RES LAB,MECH & STRUCT BRANCH,ABERDEEN PROVING GROUND,MD 21005. NR 10 TC 0 Z9 0 U1 0 U2 0 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB SN 0965-9978 J9 ADV ENG SOFTW JI Adv. Eng. Softw. PY 1993 VL 16 IS 3 BP 145 EP 152 DI 10.1016/0965-9978(93)90011-H PG 8 WC Computer Science, Interdisciplinary Applications; Computer Science, Software Engineering; Engineering, Multidisciplinary SC Computer Science; Engineering GA LH715 UT WOS:A1993LH71500001 ER PT J AU SCHELBERG, JD AF SCHELBERG, JD TI PREHISTORIC EXCHANGE AND SOCIOPOLITICAL DEVELOPMENT IN THE PLATEAU SOUTHWEST - DOUGLASS,AA SO AMERICAN ANTIQUITY LA English DT Book Review RP SCHELBERG, JD (reprint author), USA,ALBUQUERQUE,NM, USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU SOC AMER ARCHAEOLOGY PI WASHINGTON PA 900 SECOND ST., NE WASHINGTON, DC 20002-3557 SN 0002-7316 J9 AM ANTIQUITY JI Am. Antiq. PD JAN PY 1993 VL 58 IS 1 BP 175 EP 176 DI 10.2307/281470 PG 2 WC Anthropology; Archaeology SC Anthropology; Archaeology GA KX084 UT WOS:A1993KX08400019 ER PT J AU STAJDUHAR, KC LAIRD, JR ROGAN, KM WORTHAM, DC AF STAJDUHAR, KC LAIRD, JR ROGAN, KM WORTHAM, DC TI CORONARY ARTERIAL ECTASIA - INCREASED PREVALENCE IN PATIENTS WITH ABDOMINAL AORTIC-ANEURYSM AS COMPARED TO OCCLUSIVE ATHEROSCLEROTIC PERIPHERAL VASCULAR-DISEASE SO AMERICAN HEART JOURNAL LA English DT Article AB Coronary artery ectasia (CAE) is the saccular or fusiform dilatation of a coronary artery. CAE is found in 1.2% to 4.9% of patients at autopsy or during angiographic studies, with a similar prevalence of CAE found in patients with atherosclerotic peripheral vascular disease (PVD). Abdominal aortic aneurysm (AAA) and CAE are similar in pathogenesis and histology. To determine whether CAE occurs more frequently in patients with AAA than in occlusive forms of atherosclerotic PVD, a review of coronary angiograms was performed in patients who underwent cardiac catheterization and vascular reconstruction for AAA or occlusive atherosclerotic PVD of the lower extremities. Of 72 patients with AAA, 15 had CAE (20.8%) compared with only 2 of 69 patients with atherosclerotic PVD (2.9%) (p < 0.003). CAE was predominantly discrete, located in the left coronary system, and associated with significant coronary atherosclerosis. CAE may be more prevalent in patients with AAA resulting from a similar pathogenetic process. C1 WALTER REED ARMY MED CTR,CARDIOL SERV,WASHINGTON,DC 20307. MADIGAN ARMY MED CTR,CARDIOL SERV,TACOMA,WA 98431. NR 20 TC 53 Z9 54 U1 1 U2 1 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0002-8703 J9 AM HEART J JI Am. Heart J. PD JAN PY 1993 VL 125 IS 1 BP 86 EP 92 DI 10.1016/0002-8703(93)90060-M PG 7 WC Cardiac & Cardiovascular Systems SC Cardiovascular System & Cardiology GA KF521 UT WOS:A1993KF52100011 PM 8417547 ER PT J AU PREWITT, KC LAIRD, JR CAMBIER, PA WORTHAM, DC AF PREWITT, KC LAIRD, JR CAMBIER, PA WORTHAM, DC TI LATE CORONARY ANEURYSM FORMATION AFTER DIRECTIONAL ATHERECTOMY SO AMERICAN HEART JOURNAL LA English DT Note ID RESECTION RP PREWITT, KC (reprint author), WALTER REED ARMY MED CTR,CARDIOL SERV,WASHINGTON,DC 20307, USA. NR 11 TC 10 Z9 10 U1 0 U2 0 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0002-8703 J9 AM HEART J JI Am. Heart J. PD JAN PY 1993 VL 125 IS 1 BP 249 EP 251 DI 10.1016/0002-8703(93)90087-P PG 3 WC Cardiac & Cardiovascular Systems SC Cardiovascular System & Cardiology GA KF521 UT WOS:A1993KF52100038 PM 8417531 ER PT J AU KADAKIA, SC WONG, RKH AF KADAKIA, SC WONG, RKH TI GRADED PNEUMATIC DILATION USING RIGIFLEX ACHALASIA DILATORS IN PATIENTS WITH PRIMARY ESOPHAGEAL ACHALASIA SO AMERICAN JOURNAL OF GASTROENTEROLOGY LA English DT Article ID COMPARING FORCEFUL DILATATION; BALLOON DILATORS; ESOPHAGOMYOTOMY AB Pneumatic dilation is the initial therapy for primary esophageal achalasia. Recently, polyethylene balloon (Rigiflex) dilators have been used with varying success and complication rate. We performed a total of 47 dilations in 29 consecutive patients with achalasia using the Rigiflex dilators. The 3.0-cm balloon was always used first. If there was no symptomatic response, a 3.5-cm balloon was used after 4-8 wk. If there was still no symptomatic response after 4-8 wk, a 4.0-cm dilator was used. Eighteen (62%) patients were successfully dilated with a 3.0-cm balloon only. Of 11 patients not responding to a 3.0-cm balloon, five were dilated successfully with a 3.5-cm balloon. Of six patients not responding to a 3.5-cm balloon, four were successfully dilated with a 4.0-cm balloon dilator. Two patients eventually required surgery. The overall success with Rigiflex balloon dilator was achieved in 27 of 29 (93%) patients. There were no complications. We conclude that pneumatic dilation for esophageal achalasia performed in a graded fashion starting with Rigiflex 3.0-cm balloon dilator has a high success rate without complications in patients with achalasia. C1 WALTER REED ARMY MED CTR,DEPT MED,GASTROENTEROL SERV,WASHINGTON,DC 20307. RP KADAKIA, SC (reprint author), BROOKE ARMY MED CTR,DEPT MED,GASTROENTEROL SERV,FT SAM HOUSTON,TX 78234, USA. NR 19 TC 114 Z9 119 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0002-9270 J9 AM J GASTROENTEROL JI Am. J. Gastroenterol. PD JAN PY 1993 VL 88 IS 1 BP 34 EP 38 PG 5 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA KG780 UT WOS:A1993KG78000007 PM 8420271 ER PT J AU PARKER, AL KADAKIA, SC MACCINI, DM CASSADAY, MA ANGUEIRA, CE AF PARKER, AL KADAKIA, SC MACCINI, DM CASSADAY, MA ANGUEIRA, CE TI DISAPPEARANCE OF DUODENAL POLYPS IN GARDNERS-SYNDROME WITH SULINDAC THERAPY SO AMERICAN JOURNAL OF GASTROENTEROLOGY LA English DT Note ID INTESTINAL TUMORS; INDOMETHACIN; COLON; RATS AB Duodenal polyps with a malignant potential pose a serious threat to Gardner's patients. Several reports have shown regression or disappearance of colonic polyps with sulindac therapy. We report the first case of disappearance of duodenal polyps with sulindac. C1 WILLIAM BEAUMONT ARMY MED CTR,EL PASO,TX 79920. RP PARKER, AL (reprint author), BROOKE ARMY MED CTR,DEPT MED,GASTROENTEROL SERV,FT SAM HOUSTON,TX 78234, USA. NR 10 TC 28 Z9 28 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0002-9270 J9 AM J GASTROENTEROL JI Am. J. Gastroenterol. PD JAN PY 1993 VL 88 IS 1 BP 93 EP 94 PG 2 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA KG780 UT WOS:A1993KG78000019 PM 8420281 ER PT J AU RYALS, BD BROWN, DC LEVIN, SW AF RYALS, BD BROWN, DC LEVIN, SW TI DUPLICATION OF THE PITUITARY-GLAND AS SHOWN BY MR SO AMERICAN JOURNAL OF NEURORADIOLOGY LA English DT Article DE PITUITARY GLAND, ABNORMALITIES AND ANOMALIES; PITUITARY GLAND, MAGNETIC RESONANCE AB Duplication of the pituitary gland is a rare malformation. The authors describe a patient with features of the median cleft face syndrome (hypertelorism, V-shaped hairline, and developmental delay) who exhibited duplication of the pituitary gland and diffuse thickening of the hypothalamus (hypothalmic hamartoma) as shown by MR. The embryology of the developing pituitary gland and pathogenesis of pituitary duplication are discussed. C1 WALTER REED ARMY MED CTR,CHILD NEUROL SERV,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,DEPT DIAGNOST RADIOL,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,DEPT PEDIAT,WASHINGTON,DC 20307. UNIFORMED SERV UNIV HLTH SCI,DEPT RADIOL & NUCL MED,BETHESDA,MD 20814. UNIFORMED SERV UNIV HLTH SCI,DEPT NEUROL,BETHESDA,MD 20814. UNIFORMED SERV UNIV HLTH SCI,DEPT PEDIAT,BETHESDA,MD 20814. RP RYALS, BD (reprint author), FAMC,DEPT NEUROL,AURORA,CO 80015, USA. NR 10 TC 17 Z9 18 U1 0 U2 0 PU AMER SOC NEURORADIOLOGY PI OAK BROOK PA 2210 MIDWEST RD, OAK BROOK, IL 60521 SN 0195-6108 J9 AM J NEURORADIOL JI Am. J. Neuroradiol. PD JAN-FEB PY 1993 VL 14 IS 1 BP 137 EP 139 PG 3 WC Clinical Neurology; Neuroimaging; Radiology, Nuclear Medicine & Medical Imaging SC Neurosciences & Neurology; Radiology, Nuclear Medicine & Medical Imaging GA KJ756 UT WOS:A1993KJ75600022 PM 8427075 ER PT J AU HO, VB FITZ, CR YODER, CC GEYER, CA AF HO, VB FITZ, CR YODER, CC GEYER, CA TI RESOLVING MR FEATURES IN OSMOTIC MYELINOLYSIS (CENTRAL PONTINE AND EXTRAPONTINE MYELINOLYSIS) SO AMERICAN JOURNAL OF NEURORADIOLOGY LA English DT Article DE BRAIN STEM, MAGNETIC RESONANCE; DEGENERATIVE BRAIN DISEASE; DEMYELINATING DISEASE ID BRAIN; HYPONATREMIA; IMAGES AB Osmotic myelinolysis is a distinctive clinical syndrome with characteristic MR features in the central pons (central pontine myelinolysis) and in other locations (extrapontine myelinolysis). We describe the resolving MR features in an adolescent who has experienced complete neurologic recovery. Regions of involvement manifested increased T2 signal intensity. The extrapontine involvement was noted to resolve earlier with interim-increased T1-weighted signal. The mechanism for the variable appearance of increased T1 signal intensity is discussed. C1 WALTER REED ARMY MED CTR,DEPT RADIOL,WASHINGTON,DC 20307. GEORGE WASHINGTON UNIV,DEPT RADIOL,WASHINGTON,DC 20052. CHILDRENS NATL MED CTR,WASHINGTON,DC 20010. WALTER REED ARMY MED CTR,DEPT PEDIAT NEUROL,WASHINGTON,DC 20307. NR 15 TC 52 Z9 54 U1 0 U2 0 PU AMER SOC NEURORADIOLOGY PI OAK BROOK PA 2210 MIDWEST RD, OAK BROOK, IL 60521 SN 0195-6108 J9 AM J NEURORADIOL JI Am. J. Neuroradiol. PD JAN-FEB PY 1993 VL 14 IS 1 BP 163 EP 167 PG 5 WC Clinical Neurology; Neuroimaging; Radiology, Nuclear Medicine & Medical Imaging SC Neurosciences & Neurology; Radiology, Nuclear Medicine & Medical Imaging GA KJ756 UT WOS:A1993KJ75600026 PM 8427080 ER PT J AU PEELE, ME CARR, FE BAKER, JR WARTOFSKY, L BURMAN, KD AF PEELE, ME CARR, FE BAKER, JR WARTOFSKY, L BURMAN, KD TI TSH BETA-SUBUNIT GENE-EXPRESSION IN HUMAN-LYMPHOCYTES SO AMERICAN JOURNAL OF THE MEDICAL SCIENCES LA English DT Article DE GENE; LYMPHOCYTES; TSH ID NEURO-ENDOCRINE SYSTEMS; THYROTROPIN TSH; MOLECULAR-BASIS; HORMONE; IMMUNE; CORTICOTROPIN; INTERFERON; ENDORPHIN; MECHANISM AB Production of neuroendocrine peptides by human lymphocytes is thought to facilitate control of the immune response. The presence of neuroendocrine peptide gene expression, specifically the TSH beta subunit gene, was studied in human lymphocytes using Northern blot analysis and polymerase chain reaction (PCR) techniques. Northern blot analysis of human lymphocyte RNA probed with a TSH beta cDNA probe failed to demonstrate TSH beta subunit steady state message levels. PCR amplification of lymphocyte-derived cDNA using TSH beta subunit complementary primers resulted in amplification of a .38 Kb DNA fragment, confirming expression and initial exonic splicing of TSH beta subunit gene exons 2 and 3 in human lymphocytes. Sequence analysis of this .38 Kb DNA fragment demonstrated conservation of exon borders after splicing (exons 2 and 3) and predicted an amino acid translation product similar, if not identical, to human TSH beta peptide sequence. Hybridization with a TSH beta subunit cDNA probe of PCR-amplified reverse-transcribed lymphocyte RNA suggested that: (1) the abundance of TSH beta subunit gene transcripts in human lymphocytes is less than the relative abundance in T3-treated pituitary; and (2) this messenger RNA may be modulated by the presence of certain thyromimetic compounds (T2, T3, TRIAC). C1 WALTER REED ARMY MED CTR,ENDOCRINE METAB SERV,7D,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,DEPT CLIN INVEST,KYLE METAB UNIT,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,DEPT MED,WASHINGTON,DC 20307. UNIFORMED SERV UNIV HLTH SCI,BETHESDA,MD 20814. NR 17 TC 17 Z9 17 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0002-9629 J9 AM J MED SCI JI Am. J. Med. Sci. PD JAN PY 1993 VL 305 IS 1 BP 1 EP 7 PG 7 WC Medicine, General & Internal SC General & Internal Medicine GA KF047 UT WOS:A1993KF04700001 PM 8416675 ER PT J AU CHAMP, JD AF CHAMP, JD TI CASE-REPORT - AZOTEMIA SECONDARY TO ENALAPRIL AND DIURETIC USE AND THE DIAGNOSIS OF RENOVASCULAR HYPERTENSION SO AMERICAN JOURNAL OF THE MEDICAL SCIENCES LA English DT Article DE ACUTE; DECISION SUPPORT TECHNIQUES; KIDNEY FAILURE; ENALAPRIL; HYDROCHLOROTHIAZIDE; OBSTRUCTION; RENAL ARTERY ID CAPTOPRIL AB When administered to a 45-year-old woman who was ill with severe hypertension, combined enalapril and hydrochlorothiazide therapy resulted in acute renal failure, leading to a successful search for renal artery stenosis. Acute renal failure as an adverse reaction to enalapril therapy occurs in approximately 20% of patients with secondary hypertension from renovascular disease. On the other hand, in a group of essential hypertensives this occurs at a rate of approximately 0.2%. Thus, a likelihood ratio of 100 is produced, and given the prevalence of renovascular hypertension of approximately 2% in all hypertensives, a posterior probability of 0.67 can be calculated. The occurrence of this adverse effect should indicate that a diagnostic work-up to rule out renovascular hypertension in such patients should be pursued. The sensitivity and specificity of this ''test'' are 0.20 and 0.998, respectively. This illustrates that the mathematic aids in decision theory need not be applied solely to those more traditional aspects of diagnostic testing, but may be useful in other situations as well. C1 USA,MED DEPT ACTIV,APO,NEW YORK,NY. NR 5 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0002-9629 J9 AM J MED SCI JI Am. J. Med. Sci. PD JAN PY 1993 VL 305 IS 1 BP 25 EP 27 DI 10.1097/00000441-199301000-00005 PG 3 WC Medicine, General & Internal SC General & Internal Medicine GA KF047 UT WOS:A1993KF04700005 PM 8416678 ER PT J AU MUSIO, F OLDER, SA JENKINS, T GREGORIE, EM AF MUSIO, F OLDER, SA JENKINS, T GREGORIE, EM TI CASE-REPORT - CEREBRAL VENOUS THROMBOSIS AS A MANIFESTATION OF ACUTE ULCERATIVE-COLITIS SO AMERICAN JOURNAL OF THE MEDICAL SCIENCES LA English DT Article DE ACUTE ULCERATIVE COLITIS, CEREBRAL VENOUS THROMBOSIS; HYPERCOAGULABLE STATE ID INFLAMMATORY BOWEL-DISEASE; SAGITTAL SINUS THROMBOSIS; COMPLICATING ORAL CONTRACEPTION; CROHNS-DISEASE; PROTEIN-S; DEFICIENCY; COAGULATION; PATHOLOGY; INFUSION; THERAPY AB Ulcerative colitis is associated with a number of extraintestinal complications, including the infrequent occurrence of thromboembolic disease. Cerebral venous thrombosis is extremely rare, with only 15 cases reported in the literature. The outcome in this group of patients is poor; the result in more than 80% of the cases is permanent neurologic sequelae or death. The precise mechanisms involved in thrombogenesis remain unclear. A hypercoagulable state may occur in ulcerative colitis because of well-documented associations of thrombocytosis, elevated factors V and VIII and fibrinogen, and decreased antithrombin III. Treatment regimens for cerebral venous thrombosis remain controversial and include anticoagulation with heparin, surgical thrombectomy, and systemic and local infusion of fibrinolytic regimens. A conservative approach with antiedemic agents, anticonvulsants, antiplatelet therapy, and acetazolamide also may be beneficial and offers a substantially reduced hemorrhagic potential. A case of primary superior sagittal sinus thrombosis associated with active ulcerative colitis treated by the latter method is reported. The patient's neurologic recovery was complete, with recanalization of the thrombosed venous sinus being demonstrated by magnetic resonance imaging studies. C1 BROOKE ARMY MED CTR,DEPT SURG,NEUROSURG SERV,FT SAM HOUSTON,TX 78234. RP MUSIO, F (reprint author), BROOKE ARMY MED CTR,DEPT MED,HEMATOL SERV,FT SAM HOUSTON,TX 78234, USA. NR 73 TC 32 Z9 33 U1 0 U2 1 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0002-9629 J9 AM J MED SCI JI Am. J. Med. Sci. PD JAN PY 1993 VL 305 IS 1 BP 28 EP 35 DI 10.1097/00000441-199301000-00006 PG 8 WC Medicine, General & Internal SC General & Internal Medicine GA KF047 UT WOS:A1993KF04700006 PM 8416679 ER PT J AU SASAKI, DM PANG, L MINETTE, HP WAKIDA, CK FUJIMOTO, WJ MANE, SJ KUNIOKA, R MIDDLETON, CR AF SASAKI, DM PANG, L MINETTE, HP WAKIDA, CK FUJIMOTO, WJ MANE, SJ KUNIOKA, R MIDDLETON, CR TI ACTIVE SURVEILLANCE AND RISK-FACTORS FOR LEPTOSPIROSIS IN HAWAII SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID AGGLUTININS; SEROSURVEY AB A clinic-hospital-based leptospirosis surveillance program was conducted to determine the morbidity and risk factors in nonepidemic settings The study was conducted on two islands, Kauai and Hawaii (Big Island), in the state of Hawaii for one year during 1988 and 1989. An active, more comprehensive case detection system was used on the Big Island that enabled us to determine the incidence of clinical disease. Subjects from both islands were used to conduct a case-control study for risk factors One hundred seventy-two subjects from the Big Island (who presented with any two of the following symptoms: fever, headache, myalgia, or nausea/vomiting) were enrolled in the study. Twenty cases were diagnosed by culture, serology, or fluorescent antibody tissue staining at autopsy. Six cases required hospitalization and two succumbed to fatal infections. We estimated that these cases represented an annual incidence rate of 128 per 100,000 person-years in our target population. For 33 cases, 77 controls were matched for island, age, sex, and time of onset of illness. Interviews were conducted retrospectively in a double-blinded fashion with cases and controls and evaluated approximately 30 risk factors. Factors that were associated most strongly with development of leptospirosis were household use of rainwater catchment systems (P = 0.003), presence of skin cuts during the incubation period (P = 0.008), contact with cattle or the urine of cattle (P = 0.05 and P = 0.03, respectively), and handling of animal tissues (P = 0.005). Suspected risk factors that did not show an association with the disease were contact with mud or freshwater, swimming in freshwater, handling of garbage, and keeping of pets. Our study showed that leptospirosis is a surprisingly common disease, accounting for a high proportion of flu-like illness. Furthermore, a case-control study is relatively simple to conduct and useful for identifying risk factors specific to each population and setting. C1 HAWAII STATE DEPT HLTH,DIV COMMUNICABLE DIS,EPIDEMIOL BRANCH,POB 3378,HONOLULU,HI 96801. TRIPLER ARMY MED CTR,HONOLULU,HI 96859. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. HAWAII STATE DEPT HLTH,HILO,HI 96720. HAWAII STATE DEPT HLTH,LIHUE,HI 96766. NR 21 TC 76 Z9 80 U1 0 U2 4 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD JAN PY 1993 VL 48 IS 1 BP 35 EP 43 PG 9 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA KL730 UT WOS:A1993KL73000006 PM 8427386 ER PT J AU KYLE, DE MILHOUS, WK ROSSAN, RN AF KYLE, DE MILHOUS, WK ROSSAN, RN TI REVERSAL OF PLASMODIUM-FALCIPARUM RESISTANCE TO CHLOROQUINE IN PANAMANIAN AOTUS MONKEYS SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID CALCIUM-ANTAGONISTS; MALARIA; INFECTIONS; INVITRO; CYPROHEPTADINE; PARASITES; QUININE AB An Aotus-Plasmodium falciparum model was used to determine if chloroquine resistance could be reversed in vivo. The putative resistance modulators tested all reverse chloroquine resistance in vitro and included verapamil, chlorpromazine, prochlorperazine, cyproheptadine, ketotifen, a tiapamil analog (Ro 11-2933), and a chlorpromazine analog (SKF 2133-A). Combinations of chloroquine plus chlorpromazine or prochlorperazine confirmed reversal of chloroquine resistance as exhibited by cures obtained in six Aotus monkeys infected with chloroquine-resistant P. falciparum (Vietnam Smith/RE strain) and rapid clearance of parasitemia, followed by recrudescence in six additional monkeys. The results indicate the following order of in vivo efficacy for reversing chloroquine resistance in Aotus: chlorpromazine > prochlorperazine much greater than desipramine much greater than Ro 11-2933 (tiapamil analog) > ketotifen. Cyproheptadine and verapamil were not effective in reversing chloroquine resistance and probable drug toxicity was observed with these drugs in combination with chloroquine. C1 WALTER REED ARMY INST RES,DEPT PARASITOL,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307. GORGAS MEM LAB,PANAMA CITY,PANAMA. NR 20 TC 46 Z9 48 U1 0 U2 1 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD JAN PY 1993 VL 48 IS 1 BP 126 EP 133 PG 8 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA KL730 UT WOS:A1993KL73000018 PM 8427381 ER PT J AU MATHER, B AF MATHER, B TI MATHER,KATHARINE OCTOBER 21, 1916 - FEBRUARY 4, 1991 - MEMORIAL SO AMERICAN MINERALOGIST LA English DT Item About an Individual RP MATHER, B (reprint author), USA,CORPS ENGINEERS,VICKSBURG,MS 39180, USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU MINERALOGICAL SOC AMER PI WASHINGTON PA 1130 17TH ST NW SUITE 330, WASHINGTON, DC 20036 SN 0003-004X J9 AM MINERAL JI Am. Miner. PD JAN-FEB PY 1993 VL 78 IS 1-2 BP 239 EP 240 PG 2 WC Geochemistry & Geophysics; Mineralogy SC Geochemistry & Geophysics; Mineralogy GA KM433 UT WOS:A1993KM43300029 ER PT J AU BUTLER, JD LEVIN, SW FACCHIANO, A MUKHERJEE, AB AF BUTLER, JD LEVIN, SW FACCHIANO, A MUKHERJEE, AB TI A HISTIDINE BINDING-PROTEIN OF ESCHERICHIA-COLI - A COMPONENT OF CYSTINE BINDING-PROTEIN OF ESCHERICHIA-COLI SO AMINO ACIDS LA English DT Article DE AMINO ACIDS; HISTIDINE; CYSTINE; AMINO ACID BINDING PROTEINS ID TRANSPORT; ACID AB Commercially obtained cystine binding protein (CBP), an osmotic shock protein of Escherichia coli, was studied in an effort to determine its binding characteristics. Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS/PAGE) analysis of commercially obtained CBP showed three protein bands. N-terminal amino acid microsequencing and subsequent computer search revealed that the sequence of one of these proteins (25-kDa) was nearly identical to histidine binding protein (HisJ) of Salmonella typhimurium. Purification of CBP by HPLC yielded four protein peaks, of which one bound histidine exclusively. Binding was maximal at pH 5.0 to 6.0, at 4-degrees-C, did not require calcium or magnesium ions and was not inhibited by reduction of CBP disulfide bonds. Amino acids other than histidine or cystine did not bind to CBP. These data show that commercially available CBP is not a homogenous protein; it contains a histidine as well as a cystine binding component. C1 WALTER REED ARMY MED CTR,DEPT PEDIAT,EXCEPT FAMILY MEMBER PROGRAM,WASHINGTON,DC 20307. NICHHD,HUMAN GENET BRANCH,DEV GENET SECT,BETHESDA,MD 20892. RP BUTLER, JD (reprint author), NICHHD,HUMAN GENET BRANCH,GENET DIS INVOLVING SULFUR METAB UNIT,BLDG 10,ROOM 10N308,BETHESDA,MD 20892, USA. RI Facchiano, Antonio/K-5984-2016 OI Facchiano, Antonio/0000-0002-4243-2392 NR 8 TC 0 Z9 0 U1 0 U2 0 PU SPRINGER VERLAG PI NEW YORK PA 175 FIFTH AVE, NEW YORK, NY 10010 SN 0939-4451 J9 AMINO ACIDS JI Amino Acids PY 1993 VL 5 IS 1 BP 39 EP 50 DI 10.1007/BF00806191 PG 12 WC Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA LU104 UT WOS:A1993LU10400005 PM 24190643 ER PT J AU COMBS, RJ KNAPP, RB FIELD, PE AF COMBS, RJ KNAPP, RB FIELD, PE TI MIRROR VELOCITY SAMPLING ERRORS IN A MICHELSON INTERFEROMETER SO ANALYTICAL INSTRUMENTATION LA English DT Article AB Mirror velocity variations in a continuous mirror drive Michelson interferometer result in erroneous interferogram sampling. The effects of both systematic and random mirror fluctuations are evaluated. Four methods of evaluation provide a means to quantify the importance of mirror velocity errors in the Fourier spectrometer's performance as a spectroradiometer. The four methods are time interval signal analysis, sine wave test, optical chopper modulation, and examination of consecutive interferograms. Examination of consecutive interferograms includes the monitoring of a constant blackbody infrared radiation source as well as an interposed ammonia sample cell for wavenumber axis registration. Each method furnishes a known input to the interferometer modulation equation (i.e. 2upsilonnuBAR=f) and permits an internal validation of the interferometer mirror velocity evaluation results. C1 VIRGINIA POLYTECH INST & STATE UNIV,DEPT CHEM,BLACKSBURG,VA 24061. RP COMBS, RJ (reprint author), USA,CTR DEV & ENGN,EDGEWOOD RES,ABERDEEN PROVING GROUND,MD 21010, USA. NR 23 TC 6 Z9 6 U1 1 U2 1 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0743-5797 J9 ANAL INSTRUM PY 1993 VL 21 IS 3-4 BP 163 EP 194 PG 32 WC Chemistry, Analytical; Instruments & Instrumentation SC Chemistry; Instruments & Instrumentation GA MF930 UT WOS:A1993MF93000006 ER PT J AU DALAL, PS REID, R AUDIBERT, F BHAGAT, HR AF DALAL, PS REID, R AUDIBERT, F BHAGAT, HR TI DEVELOPMENT AND VALIDATION OF MURABUTIDE ASSAY BY HIGH-PERFORMANCE CAPILLARY ELECTROPHORESIS SO ANALYTICAL LETTERS LA English DT Article DE CAPILLARY ELECTROPHORESIS; MURABUTIDE AB The objective of this study was to develop an analytical technique for the assay of murabutide, a synthetic peptide, by high performance capillary electrophoresis. The analyte concentration was monitored by UV detection. Murabutide was eluted by using pH 8.0 borate buffer as the running buffer. The effect of the running buffer concentration on peak sharpness was investigated. Increasing concentration of the running buffer increased peak migration time and also improved the peak sharpness significantly. The assay technique was validated by plotting the standard curve and performing the inter-and intra-day variability studies. C1 CNRS,THERAPEUT IMMUNOL LAB,UPB 405,F-75005 PARIS,FRANCE. WALTER REED ARMY INST RES,DEPT GASTROENTEROL,WASHINGTON,DC 20307. RP DALAL, PS (reprint author), UNIV MARYLAND,SCH PHARM,DEPT PHARMACEUT,BALTIMORE,MD 21201, USA. NR 3 TC 2 Z9 2 U1 0 U2 0 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0003-2719 J9 ANAL LETT JI Anal. Lett. PY 1993 VL 26 IS 4 BP 657 EP 664 PG 8 WC Chemistry, Analytical SC Chemistry GA KV565 UT WOS:A1993KV56500004 ER PT B AU STURM, M GRENFELL, TC PEROVICH, DK AF STURM, M GRENFELL, TC PEROVICH, DK BE Steffen, K TI PASSIVE MICROWAVE MEASUREMENTS OF TUNDRA AND TAIGA SNOW COVERS IN ALASKA, USA SO ANNALS OF GLACIOLOGY, VOL 17 LA English DT Proceedings Paper CT 1992 International Symposium on Remote Sensing of Snow and Ice CY MAY 17-22, 1992 CL UNIV COLORADO BOULDER, BOULDER, CO SP INT GLACIOL SOC, UNIV COLORADO BOULDER, AMER SOC PHOTOGRAMMETRY & REMOTE SENSING, AMER GEOPHYS UNION, INT ASSOC PHYS SCI OCEAN, INT ASSOC HYDROL SCI, INT COMMISS SNOW & ICE, INT ASSOC HYDROL SCI, INT COMM REMOTE SENSING & DATA TRANSMISS HO UNIV COLORADO BOULDER C1 USA,COLD REG RES & ENGN LAB ALASKA,FT WAINWRIGHT,AK 99703. NR 0 TC 2 Z9 2 U1 0 U2 1 PU INT GLACIOLOGICAL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE, ENGLAND CB2 1ER BN 0-946417-09-1 PY 1993 BP 125 EP 130 PG 6 WC Geosciences, Multidisciplinary; Oceanography; Optics; Water Resources SC Geology; Oceanography; Optics; Water Resources GA BZ49K UT WOS:A1993BZ49K00018 ER PT B AU DAVIS, RE NOLIN, AW JORDAN, R DOZIER, J AF DAVIS, RE NOLIN, AW JORDAN, R DOZIER, J BE Steffen, K TI TOWARDS PREDICTING TEMPORAL CHANGES OF THE SPECTRAL SIGNATURE OF SNOW IN VISIBLE AND NEAR-INFRARED WAVELENGTHS SO ANNALS OF GLACIOLOGY, VOL 17 LA English DT Proceedings Paper CT 1992 International Symposium on Remote Sensing of Snow and Ice CY MAY 17-22, 1992 CL UNIV COLORADO BOULDER, BOULDER, CO SP INT GLACIOL SOC, UNIV COLORADO BOULDER, AMER SOC PHOTOGRAMMETRY & REMOTE SENSING, AMER GEOPHYS UNION, INT ASSOC PHYS SCI OCEAN, INT ASSOC HYDROL SCI, INT COMMISS SNOW & ICE, INT ASSOC HYDROL SCI, INT COMM REMOTE SENSING & DATA TRANSMISS HO UNIV COLORADO BOULDER C1 USA,COLD REG RES & ENGN LAB,HANOVER,NH 03755. OI Dozier, Jeff/0000-0001-8542-431X NR 0 TC 0 Z9 0 U1 0 U2 1 PU INT GLACIOLOGICAL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE, ENGLAND CB2 1ER BN 0-946417-09-1 PY 1993 BP 143 EP 148 PG 6 WC Geosciences, Multidisciplinary; Oceanography; Optics; Water Resources SC Geology; Oceanography; Optics; Water Resources GA BZ49K UT WOS:A1993BZ49K00021 ER PT S AU ITAGAKI, K LEMIEUX, GE AF ITAGAKI, K LEMIEUX, GE GP INT GLACIOL SOC INT GLACIOL SOC INT GLACIOL SOC TI CONNECTIVITY OF SNOW PARTICLES SO ANNALS OF GLACIOLOGY, VOL 18, 1993: PROCEEDINGS OF THE SYMPOSIUM ON SNOW AND SNOW-RELATED PROBLEMS SE Annals of Glaciology-Series LA English DT Proceedings Paper CT Symposium on Snow and Snow-Related Problems CY SEP 14-18, 1992 CL NAGAOKA, JAPAN SP INT GLACIOL SOC, JAPANESE SOC SNOW & ICE, NIIGATA PREFECTURE, NAGAOKA CITY C1 USA, COLD REG RES & ENGN LAB, HANOVER, NH 03755 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU INT GLACIOLOGICAL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE CB2 1ER, ENGLAND SN 0260-3055 BN 0-946417-10-5 J9 ANN GLACIOL-SER PY 1993 VL 18 BP 7 EP 10 PG 4 WC Geosciences, Multidisciplinary; Meteorology & Atmospheric Sciences; Water Resources SC Geology; Meteorology & Atmospheric Sciences; Water Resources GA BB01P UT WOS:A1993BB01P00002 ER PT S AU ALBERT, MR AF ALBERT, MR GP INT GLACIOL SOC INT GLACIOL SOC INT GLACIOL SOC TI SOME NUMERICAL EXPERIMENTS ON FIRN VENTILATION WITH HEAT-TRANSFER SO ANNALS OF GLACIOLOGY, VOL 18, 1993: PROCEEDINGS OF THE SYMPOSIUM ON SNOW AND SNOW-RELATED PROBLEMS SE Annals of Glaciology-Series LA English DT Proceedings Paper CT Symposium on Snow and Snow-Related Problems CY SEP 14-18, 1992 CL NAGAOKA, JAPAN SP INT GLACIOL SOC, JAPANESE SOC SNOW & ICE, NIIGATA PREFECTURE, NAGAOKA CITY C1 USA, COLD REG RES & ENGN LAB, HANOVER, NH 03755 USA. NR 0 TC 16 Z9 16 U1 0 U2 2 PU INT GLACIOLOGICAL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE CB2 1ER, ENGLAND SN 0260-3055 BN 0-946417-10-5 J9 ANN GLACIOL-SER PY 1993 VL 18 BP 161 EP 165 PG 5 WC Geosciences, Multidisciplinary; Meteorology & Atmospheric Sciences; Water Resources SC Geology; Meteorology & Atmospheric Sciences; Water Resources GA BB01P UT WOS:A1993BB01P00028 ER PT J AU BLACK, PL DOWNS, MB LEWIS, MG USSERY, MA DREYER, GB PETTEWAY, SR LAMBERT, DM AF BLACK, PL DOWNS, MB LEWIS, MG USSERY, MA DREYER, GB PETTEWAY, SR LAMBERT, DM TI ANTIRETROVIRAL ACTIVITIES OF PROTEASE INHIBITORS AGAINST MURINE LEUKEMIA-VIRUS AND SIMIAN IMMUNODEFICIENCY VIRUS IN TISSUE-CULTURE SO ANTIMICROBIAL AGENTS AND CHEMOTHERAPY LA English DT Article ID SYNTHETIC HIV-1 PROTEASE; CRYSTAL-STRUCTURE; HTLV-III; RETROVIRAL PROTEASES; VIRAL INFECTIVITY; ASPARTIC PROTEASE; ESCHERICHIA-COLI; RATIONAL DESIGN; CELL LINES; MATURATION AB Rationally designed synthetic inhibitors of retroviral proteases inhibit the processing of viral polyproteins in cultures of human immunodeficiency virus type 1 (HIV-1)-infected T lymphocytes and, as a result, inhibit the infectivity of HIV-1 for such cultures. The ability of HIV-1 protease inhibitors to suppress replication of the C-type retrovirus Rauscher murine leukemia virus (R-MuLV) and the HIV-related lentivirus simian immunodeficiency virus (SIV) was examined in plaque reduction assays and syncytium reduction assays, respectively. Three of seven compounds examined blocked production of infectious R-MuLV, with 50% inhibitory concentrations of less-than-or-equal-to 1 muM. Little or no cellular cytotoxicity was detectable at concentrations up to 100 muM. The same compounds which inhibited the infectivity of HIV-1 also produced activity against SIV and R-MuLV. Electron microscopic examination revealed the presence of many virions with atypical morphologies in cultures treated with the active compounds. Morphometric analysis demonstrated that the active compounds reduced the number of membrane-associated virus particles. These results demonstrate that synthetic peptide analog inhibitors of retroviral proteases significantly inhibit proteolytic processing of the gag polyproteins of R-MuLV and SIV and inhibit the replication of these retroviruses. These results are similar to those for inhibition of HIV-1 infectivity by these compounds, and thus, R-MuLV and SIV might be suitable models for the in vivo evaluation of the antiretroviral activities of these protease inhibitors. C1 USA,MED RES INST INFECT DIS,DIV PATHOL,FT DETRICK,MD 21702. US FDA,CTR DRUG EVALUAT & RES,DIV ANTIVIRAL DRUG PROD,ROCKVILLE,MD 20857. SMITHKLINE BEECHAM PHARMACEUT,DEPT MED CHEM,KING OF PRUSSIA,PA 19406. SMITHKLINE BEECHAM PHARMACEUT,DEPT ANTIINFECT,KING OF PRUSSIA,PA 19406. RP BLACK, PL (reprint author), SO RES INST,FREDERICK RES CTR,FREDERICK,MD 21701, USA. FU PHS HHS [1U01A125617] NR 36 TC 14 Z9 15 U1 0 U2 2 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0066-4804 J9 ANTIMICROB AGENTS CH JI Antimicrob. Agents Chemother. PD JAN PY 1993 VL 37 IS 1 BP 71 EP 77 PG 7 WC Microbiology; Pharmacology & Pharmacy SC Microbiology; Pharmacology & Pharmacy GA KF247 UT WOS:A1993KF24700013 PM 8381640 ER PT J AU SMEE, DF GILBERT, J LEONHARDT, JA BARNETT, BB HUGGINS, JH SIDWELL, RW AF SMEE, DF GILBERT, J LEONHARDT, JA BARNETT, BB HUGGINS, JH SIDWELL, RW TI TREATMENT OF LETHAL PICHINDE VIRUS-INFECTIONS IN WEANLING LVG LAK HAMSTERS WITH RIBAVIRIN, RIBAMIDINE, SELENAZOFURIN, AND AMPLIGEN SO ANTIVIRAL RESEARCH LA English DT Article DE PICHINDE VIRUS; ARENAVIRUS; RIBAVIRIN; INTERFERON INDUCER ID NUCLEOSIDE ANALOGS; ANTIVIRAL ACTIVITY; PATHOGENESIS; INVITRO; THERAPY; RNA AB A lethal Pichinde (An 4763 strain) virus infection was produced in 3-week-old random-bred Golden Syrian (LVG/Lak strain) hamsters inoculated intraperitoneally with virus, causing mortality in 6-9 days. High virus titers (greater-than-or-equal-to 10(7.5) cell culture infectious doses/g) were present in visceral organs, serum, brain and salivary glands near the time of death. Intraperitoneal treatments with ribavirin (10 and 32 mg/kg) and ribamidine (32, 100, and 320 mg/kg) for 10 days starting 24 h after virus challenge significantly decreased mortality and reduced virus titers by 100- to > 10 000-fold in liver, spleen, brain, and serum. Serum alanine aminotransferase (an indicator of liver damage) was also reduced in animals treated with the two compounds (ribavirin at 32 mg/kg; ribamidine at 100 and 320 mg/kg). Intraperitoneal selenazofurin (1-100 mg/kg per day for 10 days) and ampligen (0.5 and 5 mg/kg every other day for 5 injections) treatments provided neither protection from the lethal infection nor increased mean survival times. In fact, selenazofurin was overtly toxic, causing death of uninfected hamsters at 32 and 100 mg/kg. The random-bred LVG/Lak hamster appears to be a viable and cost-effective model for evaluating new therapies for arenavirus infections. C1 USA,MED RES INST INFECT DIS,DIV VIROL,FT DETRICK,MD. UTAH STATE UNIV,ANTIVIRAL PROGRAM,LOGAN,UT 84322. UTAH STATE UNIV,DEPT BIOL,LOGAN,UT 84322. NR 25 TC 30 Z9 33 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0166-3542 J9 ANTIVIR RES JI Antiviral Res. PD JAN PY 1993 VL 20 IS 1 BP 57 EP 70 DI 10.1016/0166-3542(93)90059-R PG 14 WC Pharmacology & Pharmacy; Virology SC Pharmacology & Pharmacy; Virology GA KK253 UT WOS:A1993KK25300006 PM 8384433 ER PT B AU KOWALSKI, DG BAGLEY, CF AF KOWALSKI, DG BAGLEY, CF BE Heatwole, CD TI UNITED-STATES-ARMY NATURAL-RESOURCES INFORMATION MANAGEMENT SO APPLICATION OF ADVANCED INFORMATION TECHNOLOGIES: EFFECTIVE MANAGEMENT OF NATURAL RESOURCES SE ASAE PUBLICATION LA English DT Proceedings Paper CT Conference on Applications of Advanced Information Technologies: Effective Management of Natural Resources CY JUN 18-19, 1993 CL SPOKANE, WA SP ASAE, INFORMAT & ELECT TECHNOL DIV DE LAND CONDITION-TREND ANALYSIS (LCTA); GEOGRAPHIC RESOURCES ANALYSIS SUPPORT SYSTEM (GRASS); GEOGRAPHIC INFORMATION SYSTEM (GIS); GRAPHICS USER INTERFACE (GUI); AUTOMATED DATA COLLECTION; SATELLITE IMAGES; NEURAL NETWORKS; MULTIMEDIA AND HYPERMEDIA; GLOBAL ELECTRONIC NETWORKING C1 USA,DIV ENVIRONM NAT RESOURCES,CONSTRUCT ENGN RES LABS,CHAMPAIGN,IL. NR 0 TC 0 Z9 0 U1 0 U2 1 PU AMER SOC AGRICULTURAL ENGINEERS PI ST JOSEPH PA 2950 NILES RD, ST JOSEPH, MI 49085-9659 BN 0-929355-39-3 J9 ASAE PUBL PY 1993 VL 93 IS 4 BP 1 EP 8 PG 8 WC Computer Science, Information Systems; Soil Science SC Computer Science; Agriculture GA BA28Q UT WOS:A1993BA28Q00001 ER PT J AU SWENSON, GW AF SWENSON, GW TI A STANDING-WAVE FACILITY FOR LOW-FREQUENCY IMPEDANCE ABSORPTION MEASUREMENT SO APPLIED ACOUSTICS LA English DT Note AB A facility for normal-incidence acoustic impedance and absorption coefficient measurement in the frequency range 20-85 Hz has been developed at the US Army Construction Engineering Research Laboratories. The system consists of an enclosed waveguide operating in the fundamental mode, with an array of microphones and data processing electronics for determining the complex reflection coefficient of a surface two meters square. RP SWENSON, GW (reprint author), USA,CONSTRUCT ENGN RES LAB,CHAMPAIGN,IL 61826, USA. NR 0 TC 2 Z9 2 U1 0 U2 0 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB SN 0003-682X J9 APPL ACOUST JI Appl. Acoust. PY 1993 VL 40 IS 4 BP 355 EP 362 DI 10.1016/0003-682X(93)90094-M PG 8 WC Acoustics SC Acoustics GA LY751 UT WOS:A1993LY75100004 ER PT J AU FOSDICK, R ZHANG, Y AF FOSDICK, R ZHANG, Y TI THE TORSION PROBLEM FOR A NONCONVEX STORED ENERGY FUNCTION SO ARCHIVE FOR RATIONAL MECHANICS AND ANALYSIS LA English DT Article ID PHASE; SHEAR C1 UNIV MINNESOTA,USA,CTR HIGH PERFORMANCE COMP,MINNEAPOLIS,MN 55415. RP FOSDICK, R (reprint author), UNIV MINNESOTA,MINNEAPOLIS,MN 55455, USA. NR 15 TC 13 Z9 14 U1 0 U2 0 PU SPRINGER VERLAG PI NEW YORK PA 175 FIFTH AVE, NEW YORK, NY 10010 SN 0003-9527 J9 ARCH RATION MECH AN JI Arch. Ration. Mech. Anal. PY 1993 VL 122 IS 4 BP 291 EP 322 DI 10.1007/BF00375138 PG 32 WC Mathematics, Applied; Mechanics SC Mathematics; Mechanics GA MB390 UT WOS:A1993MB39000001 ER PT J AU PAGE, CP BOHNEN, JMA FLETCHER, JR MCMANUS, AT SOLOMKIN, JS WITTMANN, DH AF PAGE, CP BOHNEN, JMA FLETCHER, JR MCMANUS, AT SOLOMKIN, JS WITTMANN, DH TI ANTIMICROBIAL PROPHYLAXIS FOR SURGICAL WOUNDS - GUIDELINES FOR CLINICAL CARE SO ARCHIVES OF SURGERY LA English DT Article; Proceedings Paper CT 12TH ANNUAL MEETING OF THE SURGICAL INFECTION SOC CY APR 09, 1992 CL LOS ANGELES, CA SP SURG INFECT SOC ID PENETRATING ABDOMINAL-TRAUMA; SYSTEMIC ANTIBIOTIC-PROPHYLAXIS; BETA-LACTAM ANTIBIOTICS; HIGH-RISK; RANDOMIZED TRIAL; CARDIAC-SURGERY; BYPASS-SURGERY; NEUROSURGICAL OPERATIONS; COLORECTAL OPERATIONS; TOPICAL ANTIBIOTICS AB Prophylactic administration of antibiotics can decrease postoperative morbidity, shorten hospitalization, and reduce the overall costs attributable to infections. Principles of prophylaxis include providing effective levels of antibiotics in the decisive interval, and, in most instances, limiting the course to intraoperative coverage only. Use in The National Research Council clean contaminated operations is appropriate and, in many instances, has been proven beneficial. Antibiotic prophylaxis is also indicated for clean operations, such as those involved with insertion of prosthetic devices, that are associated with low infection risk and high morbidity. Extension of antibiotic prophylaxis to other categories of clean wounds should be limited to patients with two or more risk factors established by criteria in the study of the efficacy of nosocomial infection control (SENIC) because the baseline infection rate in these patients is high enough to justify their use. Cefazolin (or cefoxitin when anaerobic coverage is necessary) remains the mainstay of prophylactic therapy. Selection of an alternate agent should be based on specific contraindications, local infection control surveillance data, and the results of clinical trials. Newer criteria for determining the risk of ''site infection'' (wound and intracavitary) are in evolution and may lead to modification of these recommendations over the next several years. C1 MED COLL WISCONSIN,MILWAUKEE,WI 53226. UNIV CINCINNATI,COLL MED,CINCINNATI,OH 45221. UNIV TORONTO,DEPT SURG,TORONTO M5S 1A1,ONTARIO,CANADA. UNIV SO ALABAMA,DEPT SURG,MOBILE,AL 36688. USA,INST SURG RES,MICROBIOL BRANCH,FT SAM HOUSTON,TX 78234. RP PAGE, CP (reprint author), UNIV TEXAS,HLTH SCI CTR,DEPT SURG,7703 FLOYD CURL DR,SAN ANTONIO,TX 78284, USA. NR 99 TC 260 Z9 278 U1 0 U2 8 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0004-0010 J9 ARCH SURG-CHICAGO JI Arch. Surg. PD JAN PY 1993 VL 128 IS 1 BP 79 EP 88 PG 10 WC Surgery SC Surgery GA KG485 UT WOS:A1993KG48500012 ER PT J AU HASE, T DUBOIS, DR SUMMERS, PL DOWNS, MB USSERY, MA AF HASE, T DUBOIS, DR SUMMERS, PL DOWNS, MB USSERY, MA TI COMPARISON OF REPLICATION RATES AND PATHOGENICITIES BETWEEN THE SA-14 PARENT AND SA-14-14-2 VACCINE STRAINS OF JAPANESE ENCEPHALITIS-VIRUS IN MOUSE-BRAIN NEURONS SO ARCHIVES OF VIROLOGY LA English DT Article ID CULTURED MOSQUITO CELLS; ENVELOPE PROTEIN-E; MONOCLONAL-ANTIBODIES; PROTECTIVE IMMUNITY; ATTENUATED VACCINE; ENTRY; FLAVIVIRUSES; GLYCOPROTEIN AB The replication rates and pathogenicities of the SA 14 parent and SA 14-14-2 vaccine strains of Japanese encephalitis (JE) virus in neurons of the mouse brain following intracerebral inoculation were compared. All the mice inoculated with the SA 14 parent strain died within one week postinoculation (p.i.), whereas all the mice inoculated with the SA 14 - 14-2 vaccine strains survived without showing any signs of central nervous system (CNS) involvement. The virus titers of the mouse brains inoculated with the SA 14 strain reached progressively higher levels until day 5 when the animals died. On the other hand, the virus titers of the mouse brains inoculated with the SA 14- 14-2 strain persisted at low levels for several days and could not be detected after 10 days. In the routine electron microscopical study, a majority of neurons in the mouse brains inoculated with the SA 14 strain contained virions and showed characteristic cytopathological changes in connection with viral replication. In the brains inoculated with the SA 14- 14-2. strain, however, we failed to find neurons containing virions or showing characteristic cytopathological changes. In the alkaline phosphatase immunostaining of paraffin-embedded sections, a majority of neurons in the brains of mice inoculated with the SA 14 strain stained positively on day 5 p.i., but only a small number of neurons in scattered small foci stained positively in the brains inoculated with the SA 14- 14-2 strain. The immunogold staining of Vibratome sections also revealed the identical patterns; moreover, electron microscopical examination of the immunopositive foci of the brain inoculated with the vaccine strain revealed neurons that contained virions in dilated cisternae of rough endoplasmic reticulum (RER), indicating that the SA 14- 14-2 strain also replicated, albeit poorly, in neurons. The present results showed that upon intracerebral inoculation into mice the SA 14 parent strain of JE virus grew vigorously in a large number of neurons, killing the animals, while the SA 14- 14-2 vaccine strain grew poorly only in a small number of neurons without causing mortality. Possible mechanisms involved in the alteration of pathogenicity between the SA 14 parent virus and the SA 14- 14-2 vaccine virus are discussed. C1 WALTER REED ARMY INST RES,DEPT BIOL RES,WASHINGTON,DC 20307. USA,MED RES INST INFECT DIS,DEPT PATHOL,FT DETRICK,MD. US FDA,DIV ANTIVIRAL DRUG PROD,ROCKVILLE,MD 20857. RP HASE, T (reprint author), WALTER REED ARMY INST RES,DIV PATHOL,DEPT ULTRASTRUCT PATHOL,WASHINGTON,DC 20307, USA. NR 26 TC 18 Z9 19 U1 0 U2 0 PU SPRINGER-VERLAG WIEN PI VIENNA PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 VIENNA, AUSTRIA SN 0304-8608 J9 ARCH VIROL JI Arch. Virol. PY 1993 VL 130 IS 1-2 BP 131 EP 143 DI 10.1007/BF01319002 PG 13 WC Virology SC Virology GA LC650 UT WOS:A1993LC65000011 PM 8503779 ER PT B AU CHANG, SKW GONZALEZ, RR AF CHANG, SKW GONZALEZ, RR BE Geshwiler, M TI AIR VELOCITY PROFILES AROUND THE HUMAN-BODY SO ASHRAE TRANSACTIONS 1993, VOL 99, PT 1 SE ASHRAE TRANSACTIONS LA English DT Proceedings Paper CT 1993 Winter Meeting of the American-Society-of-Heating-Refrigerating-and-Air-Conditioning-Engineers -Incorporated CY JAN 23-27, 1993 CL CHICAGO, IL SP AMER SOC HEATING REFRIGERATING & AIR CONDITIONING ENGINEERS INC C1 USA,ENVIRONM MED RES INST,DIV BIOPHYS & BIOMED MODELING,ENVIRONM PHYSIOL & MED DIRECTORATE,NATICK,MA 01760. NR 0 TC 3 Z9 3 U1 0 U2 0 PU AMER SOC HEATING, REFRIGERATING AND AIR-CONDITIONING ENGS PI ATLANTA PA 1791 TULLIE CIRCLE NE, ATLANTA, GA 30329 J9 ASHRAE TRAN PY 1993 VL 99 BP 450 EP 458 PN 1 PG 9 WC Construction & Building Technology; Engineering, Mechanical SC Construction & Building Technology; Engineering GA BA39G UT WOS:A1993BA39G00045 ER PT B AU PERLEA, VG MATHEWS, DL WALBERG, FC AF PERLEA, VG MATHEWS, DL WALBERG, FC GP ASSOC STATE DAM SAFETY OFFICIALS TI ABUTMENT SEEPAGE REMEDIATION FOR AN EARTHEN DAM SO ASSOCIATION OF STATE DAM SAFETY OFFICIALS - 1993 ANNUAL CONFERENCE PROCEEDINGS, PROCEEDINGS AND PROCEEDINGS SUPPLEMENT LA English DT Proceedings Paper CT 1993 Annual Conference of the Association of State Dam Safety Officials CY SEP 26-29, 1993 CL KANSAS CITY, MO SP ASSOC STATE DAM SAFETY OFFICIALS C1 USA,CORPS ENGINEERS,KANSAS CITY,MO 64106. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASSOC STATE DAM SAFETY OFFICIALS PI LEXINGTON PA 450 OLD EAST VINE, 2ND FLOOR, LEXINGTON, KY 40507 PY 1993 BP A467 EP A472 PG 6 WC Engineering, Electrical & Electronic; Water Resources SC Engineering; Water Resources GA BB09Y UT WOS:A1993BB09Y00050 ER PT B AU BARBER, PD AF BARBER, PD GP ASSOC STATE DAM SAFETY OFFICIALS TI KEYNOTE ADDRESS SYNOPSIS SO ASSOCIATION OF STATE DAM SAFETY OFFICIALS - 1993 ANNUAL CONFERENCE PROCEEDINGS, PROCEEDINGS AND PROCEEDINGS SUPPLEMENT LA English DT Proceedings Paper CT 1993 Annual Conference of the Association of State Dam Safety Officials CY SEP 26-29, 1993 CL KANSAS CITY, MO SP ASSOC STATE DAM SAFETY OFFICIALS C1 USA,CORPS ENGINEERS,DIV ENGN,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASSOC STATE DAM SAFETY OFFICIALS PI LEXINGTON PA 450 OLD EAST VINE, 2ND FLOOR, LEXINGTON, KY 40507 PY 1993 BP B5 EP B16 PG 12 WC Engineering, Electrical & Electronic; Water Resources SC Engineering; Water Resources GA BB09Y UT WOS:A1993BB09Y00052 ER PT B AU YEE, YP SUTHERLAND, RA RACHELE, H TUNICK, A AF YEE, YP SUTHERLAND, RA RACHELE, H TUNICK, A BE Kohnle, A Miller, WB TI EFFECT OF AEROSOL INDUCED RADIATIVE INTERACTIONS ON ATMOSPHERIC STABILITY AND OPTICAL TURBULENCE SO ATMOSPHERIC PROPAGATION AND REMOTE SENSING II SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Atmospheric Propagation and Remote Sensing II CY APR 14-15, 1993 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,RES LAB,BATTLEFIELD ENVIRONM DIRECTORATE,WHITE SANDS MISSILE RANGE,NM 88001. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1204-X J9 P SOC PHOTO-OPT INS PY 1993 VL 1968 BP 192 EP 201 DI 10.1117/12.154823 PG 10 WC Meteorology & Atmospheric Sciences; Optics SC Meteorology & Atmospheric Sciences; Optics GA BZ45H UT WOS:A1993BZ45H00018 ER PT J AU WESENSTEN, NJ CROWLEY, J BALKIN, T KAMIMORI, G IWANYK, E PEARSON, N DEVINE, J BELENKY, G CYMERMAN, A AF WESENSTEN, NJ CROWLEY, J BALKIN, T KAMIMORI, G IWANYK, E PEARSON, N DEVINE, J BELENKY, G CYMERMAN, A TI EFFECTS OF SIMULATED HIGH-ALTITUDE EXPOSURE ON LONG-LATENCY EVENT-RELATED BRAIN POTENTIALS AND PERFORMANCE SO AVIATION SPACE AND ENVIRONMENTAL MEDICINE LA English DT Article ID P300 AB The N100, P200, N200 and P300 components of the auditory event-related potential were recorded from 10 male subjects at 0900, 1600, and 1830 hours at sea level and again following a rapid ascent to simulated 4300 m altitude. Amplitude and latency of components, ear oximetry, and concurrent performance measures (reaction time and counting errors) were assessed. Amplitude of P300 decreased, while P300 latency and reaction time increased, following ascent to altitude. However, the time course of altitude effects differed for amplitude versus latency. Components N1OO, P200, N200, and counting errors were unaffected by altitude. The results indicate that central measures of cognitive capacities are differentially sensitive to high altitude. The time course of altitude effects on P300 amplitude versus P300 latency suggests that the two measures reflect different aspects of a response to hypobaric hypoxic exposure. C1 USA,CREW LIFE SUPPORT BRANCH,FT RUCKER,AL 36360. USA,INST ENVIRONM MED,ALTITUDE RES DIV,NATICK,MA 01760. RP WESENSTEN, NJ (reprint author), WALTER REED ARMY INST RES,DEPT BEHAV BIOL,DIV NP,WASHINGTON,DC 20307, USA. NR 20 TC 25 Z9 25 U1 0 U2 3 PU AEROSPACE MEDICAL ASSOC PI ALEXANDRIA PA 320 S HENRY ST, ALEXANDRIA, VA 22314-3579 SN 0095-6562 J9 AVIAT SPACE ENVIR MD JI Aviat. Space Environ. Med. PD JAN PY 1993 VL 64 IS 1 BP 30 EP 36 PG 7 WC Public, Environmental & Occupational Health; Medicine, General & Internal; Sport Sciences SC Public, Environmental & Occupational Health; General & Internal Medicine; Sport Sciences GA KF510 UT WOS:A1993KF51000006 PM 8424737 ER PT J AU MALCONIAN, MK ROCK, PB REEVES, JT CYMERMAN, A HOUSTON, CS AF MALCONIAN, MK ROCK, PB REEVES, JT CYMERMAN, A HOUSTON, CS TI OPERATION EVEREST-II - GAS TENSIONS IN EXPIRED AIR AND ARTERIAL BLOOD AT EXTREME ALTITUDE SO AVIATION SPACE AND ENVIRONMENTAL MEDICINE LA English DT Article ID MOUNT EVEREST; MT EVEREST; EXERCISE; EXCHANGE; OXYGEN AB Measurements in alveolar gas have suggested extreme hypocapnia and alkalosis on the summit of Mt. Everest. however, tensions in both expired gas and arterial blood have not been reported for the summit of Mt. Everest (P(IO2) = 43 mm Hg). To approach the problem, we examined alveolar (and end-tidal) and arterial gas tensions in 6 healthy men who completed a 40-d chamber study to the simulated ''summit,'' with 20 d above 6,400 m and 9 d above 8,000 m. In 27 simultaneous samples of alveolar air and arterial blood for inspired oxygen tensions ranging from P(IO2) of 55 mm Hg (7,380 m) to 43 mm Hg, the mean alveolar-arterial difference was negligible for P(O2) (-0.8 +/- 2.4 {S.D.} mm Hg) and PCO2 (0.5 +/- 1.4 mm Hg). For all 6 subjects at the summit, P(ACO2) was 12.0 +/- 1.8 and P(aCO2) was 11.4 + 1.6 mm Hg, and for the two with the lowest values, alveolar and arterial P(CO2), respectively, were 9.5 and 9.8 mm Hg. Arterial pH averaged 7.53 units. We conclude that while acclimatization to severe hypoxia results in extreme hypocapnia, alkalosis is more moderate than previously reported. Alveolar gas tensions reflect well the values obtained in arterial blood. C1 USA,ENVIRONM MED RES INST,DIV ALTITUDE,NATICK,MA 01760. UNIV COLORADO,HLTH SCI CTR,DENVER,CO 80262. ARCT INST N AMER,WASHINGTON,DC. UNIV VERMONT,BURLINGTON,VT 05405. FU NHLBI NIH HHS [HL-14985, HL-17731] NR 15 TC 11 Z9 11 U1 0 U2 3 PU AEROSPACE MEDICAL ASSOC PI ALEXANDRIA PA 320 S HENRY ST, ALEXANDRIA, VA 22314-3579 SN 0095-6562 J9 AVIAT SPACE ENVIR MD JI Aviat. Space Environ. Med. PD JAN PY 1993 VL 64 IS 1 BP 37 EP 42 PG 6 WC Public, Environmental & Occupational Health; Medicine, General & Internal; Sport Sciences SC Public, Environmental & Occupational Health; General & Internal Medicine; Sport Sciences GA KF510 UT WOS:A1993KF51000007 PM 8424738 ER PT J AU THORNTON, R CALDWELL, JL AF THORNTON, R CALDWELL, JL TI THE PHYSIOLOGICAL CONSEQUENCES OF SIMULATED HELICOPTER FLIGHT IN NBC PROTECTIVE EQUIPMENT SO AVIATION SPACE AND ENVIRONMENTAL MEDICINE LA English DT Note AB The physiological effects of wearing U.S. Army aviator nuclear-biological-chemical (NBC) individual protective equipment (IPE) were evaluated in the USAARL UH-60 research flight simulator. There were 16 male aviators who flew the simulator in 4 test conditions: standard flight suit and cool cockpit, standard flight suit and hat cockpit, NBC IPE and cool cockpit, NBC IPE and hot cockpit. The cool condition was a WBGT of 17.9-degrees-C, the hot 30.6-degrees-C. Rectal temperature, mean skin temperature, and heart rate were monitored and showed significant increases for the NBC hot condition compared with the other three. Seven subjects failed to complete the sortie in the NBC hot condition, with a mean survival time of 298 min. All subjects flew for the target 6 h in the other conditions. C1 USA,AEROMED RES LAB,FT RUCKER,AL 36360. NR 8 TC 3 Z9 3 U1 0 U2 0 PU AEROSPACE MEDICAL ASSOC PI ALEXANDRIA PA 320 S HENRY ST, ALEXANDRIA, VA 22314-3579 SN 0095-6562 J9 AVIAT SPACE ENVIR MD JI Aviat. Space Environ. Med. PD JAN PY 1993 VL 64 IS 1 BP 69 EP 73 PG 5 WC Public, Environmental & Occupational Health; Medicine, General & Internal; Sport Sciences SC Public, Environmental & Occupational Health; General & Internal Medicine; Sport Sciences GA KF510 UT WOS:A1993KF51000013 PM 8424744 ER PT J AU LITOVITZ, TA KRAUSE, D PENAFIEL, M ELSON, EC MULLINS, JM AF LITOVITZ, TA KRAUSE, D PENAFIEL, M ELSON, EC MULLINS, JM TI THE ROLE OF COHERENCE TIME IN THE EFFECT OF MICROWAVES ON ORNITHINE DECARBOXYLASE ACTIVITY SO BIOELECTROMAGNETICS LA English DT Article DE COHERENCE TIME; MICROWAVE; AMPLITUDE MODULATION; ORNITHINE DECARBOXYLASE ID FREQUENCY ELECTROMAGNETIC-FIELDS; CELLS; EXPOSURE AB Previously, we demonstrated the requirement for a minimum coherence time of an applied, small amplitude (10 muT) ELF magnetic field if the field were to produce an enhancement of ornithine decarboxylase activity in L929 fibroblasts. Further investigation has revealed a remarkably similar coherence time phenomenon for enhancement of ornithine decarboxylase activity by amplitude-modulated 915 MHz microwaves of large amplitude (SAR 2.5 W/kg). Microwave fields modulated at 55, 60, or 65 Hz approximately doubled ornithine decarboxylase activity after 8 h. Switching modulation frequencies from 55 to 65 Hz at coherence times of 1.0 s or less abolished enhancement, while times of 10 s or longer provided full enhancement. Our results show that the microwave coherence effects are remarkably similar to those observed with ELF fields. (C)1993 Wiley-Liss, Inc. C1 CATHOLIC UNIV AMER,DEPT BIOL,WASHINGTON,DC 20064. CATHOLIC UNIV AMER,VITREOUS STATE LAB,WASHINGTON,DC 20064. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NR 12 TC 75 Z9 77 U1 0 U2 1 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0197-8462 J9 BIOELECTROMAGNETICS JI Bioelectromagnetics PY 1993 VL 14 IS 5 BP 395 EP 403 DI 10.1002/bem.2250140502 PG 9 WC Biology; Biophysics SC Life Sciences & Biomedicine - Other Topics; Biophysics GA MD385 UT WOS:A1993MD38500001 PM 8285913 ER PT J AU RASLEAR, TG AKYEL, Y BATES, F BELT, M LU, ST AF RASLEAR, TG AKYEL, Y BATES, F BELT, M LU, ST TI TEMPORAL BISECTION IN RATS - THE EFFECTS OF HIGH-PEAK-POWER PULSED MICROWAVE IRRADIATION SO BIOELECTROMAGNETICS LA English DT Article DE HIGH-PEAK-POWER PULSED MICROWAVES; TIME PERCEPTION; TIME DISCRIMINATION; DECISION-MAKING; RATS ID AUDITORY UNIT RESPONSES; FLUID-PERCUSSION MODEL; TIME PERCEPTION; INTERNAL CLOCK; BRAIN INJURY; SINGLE; RADIATION; CAT; METHAMPHETAMINE; NEURONS AB The effects of high-peak-power, pulsed microwaves on a time perception and discrimination task were studied in rats. Exposures were performed with the TEMPO exposure system, which produces an 80 nanosecond pulse with peak-power levels in excess of 700 megawatts. The ability to expose animals to such fields within a controlled environment is unique. As determined by calorimetry, a maximal, whole-body-averaged, specific-absorption rate of 0.072 W/kg was produced. Thus exposures were well below a recommended SAR limit of 0.4 W/kg. Power levels of transmitted microwaves were varied over a 50 dB range to obtain ascending and descending dose-response functions for each of the behavioral measures. Measures of time perception, response bias, and total trials did not change with power level. Dose-response effects were observed for discriminability (ability to distinguish between durations), session time, and trial completions (null responses, failures to respond on a trial). Covarying sound and X-ray exposures produced by TEMPO did not reliably correlate with the observed microwave effects. The observation of repeatable dose-response effects on discriminability and null responses indicates that the microwave exposures were affecting cognitive function in the rats, particularly the decision-making process. (C)1993 Wiley-Liss, Inc. C1 WALTER REED ARMY INST RES,DEPT MICROWAVE RES,WASHINGTON,DC 20307. OGDEN BIOSERV CORP,GAITHERSBURG,MD. NR 53 TC 15 Z9 15 U1 0 U2 1 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0197-8462 J9 BIOELECTROMAGNETICS JI Bioelectromagnetics PY 1993 VL 14 IS 5 BP 459 EP 478 DI 10.1002/bem.2250140507 PG 20 WC Biology; Biophysics SC Life Sciences & Biomedicine - Other Topics; Biophysics GA MD385 UT WOS:A1993MD38500006 PM 8285916 ER PT S AU OELSCHLAEGER, TA KOPECKO, DJ AF OELSCHLAEGER, TA KOPECKO, DJ BE Cabello, F Hormaeche, C Mastroeni, P Bonina, L TI MICROTUBULE-DEPENDENT VERSUS MICROFILAMENT-DEPENDENT INVASION MECHANISMS ENCODED BY CITROBACTER-FREUNDII SO BIOLOGY OF SALMONELLA SE NATO ADVANCED SCIENCE INSTITUTES SERIES, SERIES A, LIFE SCIENCES LA English DT Proceedings Paper CT NATO Advanced Research Workshop on Biology of Salmonella CY MAY 11-15, 1992 CL PORTOROSA, ITALY SP NATO, ADV SCI INST, UNIV MESSINA, MEDEVA GRP RES UK, SWISS SERUM & VACCINE RES INST C1 WALTER REED ARMY INST RES,DEPT BACTERIAL IMMUNOL,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU PLENUM PRESS DIV PLENUM PUBLISHING CORP PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 SN 0258-1213 BN 0-306-44492-5 J9 NATO ADV SCI INST SE PY 1993 VL 245 BP 401 EP 404 PG 4 WC Public, Environmental & Occupational Health; Microbiology SC Public, Environmental & Occupational Health; Microbiology GA BZ50X UT WOS:A1993BZ50X00049 ER PT J AU DUBOSE, DA HAUGLAND, R AF DUBOSE, DA HAUGLAND, R TI COMPARISONS OF ENDOTHELIAL-CELL G-ACTIN AND F-ACTIN DISTRIBUTION IN SITU AND INVITRO SO BIOTECHNIC & HISTOCHEMISTRY LA English DT Article DE ENDOTHELIAL CELLS; ACTIN; PHALLOIDIN; DNASE ID STRESS FIBERS; DEOXYRIBONUCLEASE-I; CULTURED-CELLS; DEPOLYMERIZATION; CYTOSKELETON; INSITU; NOREPINEPHRINE; POLYMERIZATION; INHIBITION; MODULATION AB Numerous studies have described the F-actin cytoskeleton; however, little information relevant to G-actin is available. The actin pools of bovine aortic endothelial cells were examined using in situ and in vitro conditions and fluorescent probes for G-(deoxyribonuclease 1, 0.3 muM) or F-actin (phalloidin, 0.2 muM). Cells in situ displayed a diffuse G-actin distribution, while F-actin was concentrated in the cell periphery and in fine stress fibers that traversed some cells. Cells of subconfluent or just confluent cultures demonstrated intense fluorescence, with many F-actin stress fibers. Postconfluent cultures resembled the condition in situ; peripheral F-actin was prominent, traversing actin stress fibers were greatly reduced and fluorescent intensity was diminished. Postconfluency had little influence on G-actin, with only an enhancement in the intensity of G-actin punctate fluorescence. When postconfluent cultures were incubated with cytochalasin D (15 min; 10(-4) M), F-actin networks were disrupted and actin punctate and diffuse fluorescence increased. G-actin fluorescence was not altered by the incubation. Although its unstructured nature may account for the minor changes observed, the stability of the G-actin pool in the presence of notable F-actin modulations suggested that filamentous actin was the key constituent involved in these actin cytoskeletal alterations. A separate finding illustrated that the concomitant use of actin probes with image enhancement and fluorescent microscopy could reveal simultaneously the G- and F-actin pools within the same cell. C1 MOLEC PROBES INC,EUGENE,OR 97402. RP DUBOSE, DA (reprint author), USA,ENVIRONM MED RES INST,NATICK,MA 01581, USA. NR 28 TC 21 Z9 21 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 1052-0295 J9 BIOTECH HISTOCHEM JI Biotech. Histochem. PD JAN PY 1993 VL 68 IS 1 BP 8 EP 16 DI 10.3109/10520299309105570 PG 9 WC Biotechnology & Applied Microbiology; Cell Biology SC Biotechnology & Applied Microbiology; Cell Biology GA KL408 UT WOS:A1993KL40800003 PM 8448251 ER PT J AU STILLMAN, MJ SHUKITTHALE, B KONG, RM LEVY, A LIEBERMAN, HR AF STILLMAN, MJ SHUKITTHALE, B KONG, RM LEVY, A LIEBERMAN, HR TI ELEVATION OF HIPPOCAMPAL EXTRACELLULAR ACETYLCHOLINE LEVELS BY METHOCTRAMINE SO BRAIN RESEARCH BULLETIN LA English DT Article DE ACETYLCHOLINE; MICRODIALYSIS; METHOCTRAMINE; MUSCARINIC RECEPTORS; M2 RECEPTOR; AUTORECEPTOR ID MUSCARINIC RECEPTOR SUBTYPES; RAT-BRAIN; RELEASE; STRIATUM; CORTEX; MICRODIALYSIS; HETEROGENEITY; ANTAGONIST; DIALYSIS; MEMORY AB Previous studies suggest that m2 muscarinic receptors serve as presynaptic autoreceptors. Blocking these receptors by selective antagonists may, therefore, lead to increased acetylcholine (ACh) release. This study assessed changes in extracellular ACh levels, via in vivo microdialysis, following administration of the m2 antagonist methoctramine. Drug or placebo (Ringer's solution) was perfused via a microdialysis probe into the CA1 hippocampal region of unrestrained, awake male Fischer rats. HPLC-EC was used for online analysis of the dialysates. Methoctramine significantly enhanced ACh release in a dose-dependent fashion as compared to placebo for the doses employed (0.25-16 muM). The present in vivo data corroborate studies that show increased ACh levels in vitro following application of m2 antagonists. RP STILLMAN, MJ (reprint author), USA,ENVIRONM MED RES INST,DIV MIL PERFORMANCE & NEUROSCI,KANSAS ST,NATICK,MA 01760, USA. NR 23 TC 23 Z9 24 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0361-9230 J9 BRAIN RES BULL JI Brain Res. Bull. PY 1993 VL 32 IS 4 BP 385 EP 389 DI 10.1016/0361-9230(93)90204-O PG 5 WC Neurosciences SC Neurosciences & Neurology GA LU134 UT WOS:A1993LU13400009 PM 8221128 ER PT J AU APLAND, JP ADLER, M SHERIDAN, RE AF APLAND, JP ADLER, M SHERIDAN, RE TI BREVETOXIN DEPRESSES SYNAPTIC TRANSMISSION IN GUINEA-PIG HIPPOCAMPAL SLICES SO BRAIN RESEARCH BULLETIN LA English DT Article DE HIPPOCAMPAL SLICE; SODIUM CHANNEL; FIELD POTENTIAL; BREVETOXIN; ELECTROPHYSIOLOGY; SYNAPTIC TRANSMISSION ID PTYCHODISCUS-BREVIS; SODIUM-CHANNELS; PYRAMIDAL NEURONS; BRAIN-SLICES; GYMNODINIUM; NERVE; TOXIN; DINOFLAGELLATE; MUSCLE; CELLS AB Extracellular recordings were obtained from area CA1 of guinea pig hippocampal slices. PbTx-3, a brevetoxin fraction isolated from the red tide dinoflagellate Ptychodiscus brevis, was applied by bath perfusion. The toxin produced a concentration-dependent depression of the orthodromically evoked population spike with an EC50 of 37.5 nM. Brevetoxin concentrations below 10 nM were without effect, and concentrations above 100 nM led to total inhibition of evoked responses. PbTx-3 did not produce spontaneous synchronous discharges but did induce afterdischarges following evoked responses in about 50% of the slices tested, particularly at concentrations between 10 nM and 100 nM. Orthodromically evoked responses were more sensitive to PbTx-3 than were those elicited by antidromic stimulation. High-Ca2+ solution, 4-aminopyridine, and tetraethylammonium failed to antagonize either orthodromic or antidromic effects of the toxin. Although the precise mechanism by which PbTx-3 depresses evoked responses is not certain, depolarization of the presynaptic nerve terminals leading to failure of transmitter release could explain the toxin's actions. This is the first report of the effects of brevetoxin applied directly to central nervous system tissue. RP APLAND, JP (reprint author), USA,MED RES INST CHEM DEP,NEUROTOXICOL BRANCH,CDR,ATTN,SGRD,UV YN,ABERDEEN PROVING GROUND,MD 21010, USA. NR 36 TC 12 Z9 14 U1 0 U2 1 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0361-9230 J9 BRAIN RES BULL JI Brain Res. Bull. PY 1993 VL 31 IS 1-2 BP 201 EP 207 DI 10.1016/0361-9230(93)90026-8 PG 7 WC Neurosciences SC Neurosciences & Neurology GA KN899 UT WOS:A1993KN89900025 PM 8384044 ER PT J AU SHERIDAN, RE AF SHERIDAN, RE TI ELECTROPHYSIOLOGICAL CHARACTERIZATION OF SODIUM-CHANNEL TYPES IN THE HCN-1A HUMAN CORTICAL CELL-LINE SO BRAIN RESEARCH BULLETIN LA English DT Article DE HCN-1A; HUMAN; CORTICAL; NEURONS; SODIUM CHANNELS; SAXITOXIN; TETRODOTOXIN ID PLANAR LIPID BILAYERS; XENOPUS OOCYTES; HIPPOCAMPAL-NEURONS; GANGLION-CELLS; NA CHANNELS; CLONED CDNA; RAT-BRAIN; CURRENTS; SAXITOXIN; TETRODOTOXIN AB Electrically evoked sodium currents were recorded under whole-cell patch clamp from undifferentiated HCN-1A cells. Peak sodium currents had a half-maximal activation, V(m) 0.5, of -22.6 +/- 1.0 mV with a voltage dependence, k(m), of 7.28 +/- 0.39 mV-1. Steady-state inactivation indicated the presence of two types of sodium channel. One type inactivated with V(h) 0.5 = -93.8 +/- 1.2 mV and k(h) = -6.8 +/- 0.4 mV-1. The second type of sodium channel inactivated with V(h)0.5 = -44.6 +/- 1.5 mV and k(h) = -7.3 +/- 0.4 mV-1. The occurrence of each channel type varied from cell to cell and ranged from 0 to 100% of the total sodium current. No variation in the rate of inactivation was seen when the holding potential was adjusted to eliminate the more negative of the two inactivation components. Application of tetrodotoxin (TTX) or saxitoxin (STX) revealed channel types with two different affinities for each toxin. TTX blocked peak sodium conductance with apparent IC50s of 22 nM and 5.3 muM. STX was more potent, with apparent IC50s of 1.6 nM and 1.2 muM. There was no statistical correlation between toxin sensitivity and steady-state inactivation voltage, suggesting that these properties varied independently among sodium channel types. RP SHERIDAN, RE (reprint author), USA,MED RES INST CHEM DEF,NEUROTOXICOL BRANCH,SGRD UV YN,ABERDEEN PROVING GROUND,MD 21010, USA. NR 26 TC 5 Z9 5 U1 1 U2 1 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0361-9230 J9 BRAIN RES BULL JI Brain Res. Bull. PY 1993 VL 30 IS 5-6 BP 577 EP 583 DI 10.1016/0361-9230(93)90085-P PG 7 WC Neurosciences SC Neurosciences & Neurology GA KQ568 UT WOS:A1993KQ56800008 PM 8384518 ER PT B AU YANKIELUN, NE FERRICK, MG AF YANKIELUN, NE FERRICK, MG GP CANADIAN SOC CIVIL ENGN TI A MILLIMETER-WAVE FM-CW RADAR FOR AUTOMATIC, CONTINUOUS RIVER STAGE MEASUREMENT SO CANADIAN SOCIETY FOR CIVIL ENGINEERING ANNUAL CONFERENCE/11TH CANADIAN HYDROTECHNICAL CONFERENCE 1993 PROCEEDINGS, VOL 1: HYDROTECHNICAL LA English DT Proceedings Paper CT Annual Conference of the Canadian-Society-for-Civil-Engineering and the 11th Canadian Hydrotechnical Conference CY JUN 08-11, 1993 CL FREDERICTON, CANADA SP CANADIAN SOC CIVIL ENGN C1 USA,COLD REG RES & ENGN LAB,HANOVER,NH 03755. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CANADIAN SOCIETY CIVIL ENGINEERING PI MONTREAL PA 2155 GUY, SUITE 840, MONTREAL PQ H3H 2R9, CANADA BN 0-921303-42-4 PY 1993 BP 107 EP 118 PG 12 WC Engineering, Civil; Water Resources SC Engineering; Water Resources GA BZ49T UT WOS:A1993BZ49T00012 ER PT J AU LIN, SS AF LIN, SS TI SURFACE CHARACTERIZATION OF ION-BEAM MODIFIED GRAPHITE SO CARBON LA English DT Article DE SURFACE CHARACTERIZATION; ION BEAMS; XPS; SAM ID CARBON AB X-ray photoelectron spectroscopic (XPS) and scanning Auger electron microscopic (SAM) techniques were used to study graphite surfaces modified by the ion beams of oxygen, nitrogen, hydrogen, argon, and methane gases with varying energies from 0.2 to 1 kV. A wide variety of various surface functional groups consisting of C-O, C-N, and N-O was produced in a short period of time. Relative abundances of these functionalities were analyzed and correlated with the experimental parameters. The results indicated that ion species and energy are the dominant factors in the formation of surface functionalities, and that variation of the radiation time from 1 to 20 minutes, produces a marginal contribution to the concentrations of these surface groups. The effect of ion radiation onto existing surface functionalities was also examined. The ion beam process yields a uniform distribution of the implant elements throughout the modified surface. RP LIN, SS (reprint author), USA,RES LAB,MAT DIRECTORATE,WATERTOWN,MA 02172, USA. NR 16 TC 12 Z9 12 U1 2 U2 3 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0008-6223 J9 CARBON JI Carbon PY 1993 VL 31 IS 3 BP 509 EP 517 DI 10.1016/0008-6223(93)90141-V PG 9 WC Chemistry, Physical; Materials Science, Multidisciplinary SC Chemistry; Materials Science GA LA629 UT WOS:A1993LA62900016 ER PT J AU ROSSIN, JA MORRISON, RW AF ROSSIN, JA MORRISON, RW TI THE EFFECTS OF MOLYBDENUM ON STABILIZING THE PERFORMANCE OF AN EXPERIMENTAL COPPER-ZINC IMPREGNATED, ACTIVATED CARBON SO CARBON LA English DT Letter DE ACTIVATED CARBON; HYDROGEN CYANIDE ID HYDROGEN-CYANIDE C1 USA,ERDEC,ABERDEEN PROVING GROUND,MD 21010. RP ROSSIN, JA (reprint author), GEOCENTERS INC,FT WASHINGTON,MD 20744, USA. NR 6 TC 11 Z9 11 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0008-6223 J9 CARBON JI Carbon PY 1993 VL 31 IS 4 BP 657 EP 659 DI 10.1016/0008-6223(93)90123-R PG 3 WC Chemistry, Physical; Materials Science, Multidisciplinary SC Chemistry; Materials Science GA LG475 UT WOS:A1993LG47500018 ER PT J AU PATTERSON, GML SMITH, CD KIMURA, LH BRITTON, BA CARMELI, S AF PATTERSON, GML SMITH, CD KIMURA, LH BRITTON, BA CARMELI, S TI ACTION OF TOLYTOXIN ON CELL MORPHOLOGY, CYTOSKELETAL ORGANIZATION, AND ACTIN POLYMERIZATION SO CELL MOTILITY AND THE CYTOSKELETON LA English DT Article DE ACTIN; MICROFILAMENT; STRESS FIBER; CYTOCHALASIN ID DISRUPT MICROFILAMENT ORGANIZATION; CYTOCHALASIN-D; ESTABLISHED LINES; SCYTOPHYCINS; LATRUNCULINS; MECHANISM; SCYTONEMA; TOXINS AB Tolytoxin, a cytostatic, antifungal macrolide produced by blue-green algae of the genus Scytonema, is a Potent, reversible inhibitor of cytokinesis in cultured mammalian cells. Treatment of KB cells with 2-16 nM tolytoxin results in profound morphological changes, beginning with the formation of zeiotic processes and culminating in nuclear protrusion. In L1210 cells, cytokinesis is inhibited by as little as 2 nM tolytoxin, while karyokinesis proceeds normally, resulting in polynucleation. Tolytoxin specifically disrupts microfilament organization in A10 cells, while having no apparent effect on microtubules or intermediate filaments. Tolytoxin inhibited actin polymerization in vitro and also caused the depolymerization or fragmentation of F-actin in vitro. Tolytoxin exhibits effects that closely resemble those of cytochalasin B but is effective at concentrations 1/50-1/1,000 that of cytochalasin B. C1 UNIV HAWAII,CTR CANC RES,HONOLULU,HI 96822. TRIPLER ARMY MED CTR,DEPT PATHOL,HONOLULU,HI 96859. RP PATTERSON, GML (reprint author), UNIV HAWAII MANOA,DEPT CHEM,HONOLULU,HI 96822, USA. FU NCI NIH HHS [CA12623] NR 31 TC 50 Z9 52 U1 0 U2 5 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0886-1544 J9 CELL MOTIL CYTOSKEL JI Cell Motil. Cytoskeleton PY 1993 VL 24 IS 1 BP 39 EP 48 DI 10.1002/cm.970240105 PG 10 WC Cell Biology SC Cell Biology GA KE686 UT WOS:A1993KE68600004 PM 8319266 ER PT J AU WINET, H HOLLINGER, JO AF WINET, H HOLLINGER, JO TI INTRAVITAL MICROSCOPIC EVIDENCE THAT POLYLACTIDE-POLYGLYCOLIDE (PLGA) DELAYS NEOOSTEOGENESIS AND NEO-ANGIOGENESIS IN HEALING BONE SO CELLS AND MATERIALS LA English DT Article DE BIO-ERODIBLE IMPLANTS; POLYLACTIDE-POLYGLYCOLIDE; BONE CHAMBER WINDOW; INTRAVITAL MICROSCOPY; BONE DEFECT; FRACTURE HEALING; BIOCOMPATIBILITY; OSTEOGENESIS; VASCULARITY; ANGIOGENESIS; TRABECULAE ID BIODEGRADABLE POLYMERS; CHAMBER; MICROCIRCULATION; COPOLYMERS; SURGERY; LACTIDE AB The bone chamber implant (BCI) has allowed monitoring a healing bone defect as well as the effect of an eroding implant on the healing process. The BCI is a useful tool and intravital microscopy a valuable technique for obtaining quantitative data chronicling osseous wound healing. The physiological parameters that form the initial data base documenting healing are neo-osteogenesis and neo-angiogenesis. This review compares and characterizes osseous wound healing in a BCI loaded with an erodible copolymer, PLGA (polylactide-polyglycolide). To determine if a statistically significant deviation from normal healing had occurred, the results were compared with present and historical controls. In the BCI PLGA erosion was accompanied by a delay in the onset of neo-osteogenesis, as measured by trabecular apposition. Concurrently, neo-angiogenesis was both detained and retarded. The neo-angiogenesis delay was interpreted as a direct consequence of the neo-osteogenesis delay since the major part of the vasculature was carried by the apposing trabeculae. Angiogenesis inhibition is more difficult to interpret until data are further analyzed to determine if apposing trabeculae in the presence of eroding PLGA carry less vasculature. C1 UNIV SO CALIF,LOS ANGELES,CA 90089. USA,INST DENT RES,WASHINGTON,DC 20310. RP WINET, H (reprint author), ORTHOPED HOSP,BONE CHAMBER LAB,2400 FLOWER ST,LOS ANGELES,CA 90007, USA. NR 29 TC 3 Z9 3 U1 1 U2 1 PU SCANNING MICROSCOPY INT PI CHICAGO PA PO BOX 66507, AMF O'HARE, CHICAGO, IL 60666 SN 1051-6794 J9 CELL MATER JI Cells Mat. PY 1993 VL 3 IS 3 BP 273 EP 281 PG 9 WC Cell Biology; Medicine, Research & Experimental; Materials Science, Biomaterials SC Cell Biology; Research & Experimental Medicine; Materials Science GA MM247 UT WOS:A1993MM24700004 ER PT B AU HAYES, S GREBOGI, C AF HAYES, S GREBOGI, C BE Pecora, LM TI CODING INFORMATION IN THE NATURAL COMPLEXITY OF CHAOS SO CHAOS IN COMMUNICATIONS SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Chaos in Communications CY JUL 14-15, 1993 CL SAN DIEGO, CA SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,RES LAB,ADELPHI,MD 20783. NR 0 TC 9 Z9 9 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1287-2 J9 P SOC PHOTO-OPT INS PY 1993 VL 2038 BP 153 EP 161 PG 9 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BZ77J UT WOS:A1993BZ77J00013 ER PT B AU PETHEL, SD BOWDEN, CM SCALORA, M AF PETHEL, SD BOWDEN, CM SCALORA, M BE Roy, R TI CHARACTERIZATION OF OPTICAL INSTABILITIES AND CHAOS USING FAST MULTILAYER PERCEPTRON TRAINING ALGORITHMS SO CHAOS IN OPTICS SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Chaos in Optics CY JUL 14-16, 1993 CL SAN DIEGO, CA SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,CTR RES DEV & ENGN,ST,WS,RD,AMSMI,WEAPONS SCI DIRECTORATE,REDSTONE ARSENAL,AL 35898. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1288-0 J9 P SOC PHOTO-OPT INS PY 1993 VL 2039 BP 129 EP 140 PG 12 WC Optics SC Optics GA BZ77H UT WOS:A1993BZ77H00013 ER PT J AU DRABICK, JJ GASSER, RA SAUNDERS, NB HADFIELD, TL ROGERS, LC BERG, BW DRABICK, CJ AF DRABICK, JJ GASSER, RA SAUNDERS, NB HADFIELD, TL ROGERS, LC BERG, BW DRABICK, CJ TI PASTEURELLA-MULTOCIDA PNEUMONIA IN A MAN WITH AIDS AND NONTRAUMATIC FELINE EXPOSURE SO CHEST LA English DT Article ID OUTBREAK AB A case of acute pneumonia due to Pasteurella multocida ssp multocida occurred in a young man with AIDS and chronic sinusitis. The pneumonia was diagnosed by bronchoscopy and responded to treatment with aztreonam. Epidemiologic investigation revealed the case was temporally related to nontraumatic exposure to cat secretions that the patient presumably had acquired via an aerosol. The cat's oral cavity was cultured and an isolate of P multocida ssp multocida with identical biochemical reactions, DNA restriction patterns, and nearly identical fatty acid profile to that of the patient's isolate was obtained suggesting they were identical strains and therefore epidemiologically linked. A control strain with identical biochemical reactions and antibiotic sensitivities exhibited different patterns. To our knowledge, this is the first such reported infection in a patient infected with human immunodeficiency virus. C1 ARMED FORCES INST PATHOL,DEPT INFECT & PARASIT DIS PATHOL,WASHINGTON,DC 20306. WALTER REED ARMY MED CTR,DEPT PULM DIS,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,INFECT DIS SERV,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,DEPT MICROBIOL,WASHINGTON,DC 20307. RP DRABICK, JJ (reprint author), WALTER REED ARMY INST RES,DEPT BACTERIAL DIS,WASHINGTON,DC 20307, USA. NR 25 TC 48 Z9 49 U1 0 U2 1 PU AMER COLL CHEST PHYSICIANS PI NORTHBROOK PA 3300 DUNDEE ROAD, NORTHBROOK, IL 60062-2348 SN 0012-3692 J9 CHEST JI Chest PD JAN PY 1993 VL 103 IS 1 BP 7 EP 11 DI 10.1378/chest.103.1.7 PG 5 WC Critical Care Medicine; Respiratory System SC General & Internal Medicine; Respiratory System GA KG019 UT WOS:A1993KG01900006 PM 8417940 ER PT J AU BRASSARD, JM JOHNSON, JE AF BRASSARD, JM JOHNSON, JE TI UNILATERAL ABSENCE OF A PULMONARY-ARTERY - DATA FROM CARDIOPULMONARY EXERCISE TESTING SO CHEST LA English DT Article AB A case of congenital, unilateral absence of a left pulmonary artery is described in a patient presenting with exertional dyspnea, Data from cardiopulmonary exercise testing suggest that the mechanism of dyspnea is secondary to a paradoxic elevation of the physiologic dead space to tidal volume ratio (VD/VT) during exercise. RP BRASSARD, JM (reprint author), BROOKE ARMY MED CTR,DEPT CLIN INVEST,PULM DIS CRIT CARE SERV,BLDG 2376,RM 367N,FT SAM HOUSTON,TX 78234, USA. NR 8 TC 12 Z9 12 U1 0 U2 0 PU AMER COLL CHEST PHYSICIANS PI NORTHBROOK PA 3300 DUNDEE ROAD, NORTHBROOK, IL 60062-2348 SN 0012-3692 J9 CHEST JI Chest PD JAN PY 1993 VL 103 IS 1 BP 293 EP 295 DI 10.1378/chest.103.1.293 PG 3 WC Critical Care Medicine; Respiratory System SC General & Internal Medicine; Respiratory System GA KG019 UT WOS:A1993KG01900065 PM 8417905 ER PT J AU SOLOMON, BL WARTOFSKY, L BURMAN, KD AF SOLOMON, BL WARTOFSKY, L BURMAN, KD TI ADJUNCTIVE CHOLESTYRAMINE THERAPY FOR THYROTOXICOSIS SO CLINICAL ENDOCRINOLOGY LA English DT Article AB OBJECTIVE Initial therapy of thyrotoxicosis usually includes beta-blockade for symptom relief and thionamides to block new thyroid hormone synthesis. In view of the increased enterohepatic circulation of thyroxine (T4) and trilodothyronine (T3) in thyrotoxicosis, we proposed that cholestyramine, an anion exchange resin which binds iodothyronines, when used adjunctively with thionamides and a beta-blocker, would lower serum iodothyronine levels faster than would standard therapy alone. DESIGN A double blind placebo-controlled cross-over design was used with patients randomly assigned to either the treatment or control groups. They received their initial treatment for two weeks (Phase 1) followed by a one-week washout period, and then crossed to the opposite treatment for two weeks (Phase 2). Standard therapy included atenolol 50 mg daily, individualized dosages of methimazole and either 4 g of cholestyramine or 4 g of placebo powder four times per day. PATIENTS Fifteen patients with thyrotoxicosis (14 Graves' disease, 1 toxic adenoma) participated in this study. MEASUREMENTS Total and free thyroxine and trilodothyronine, as well as thyroid-stimulating immunoglobulin and thyrotrophin-binding inhibitory immunoglobulin, were measured weekly. RESULTS Seven patients received cholestyramine and eight patients received placebo during Phase 1. A more rapid decline in all thyroid hormone levels was seen in the cholestyramine-treated group (F = 4-7, P < 0.01) than in the placebo group (F = 2-3.1, P = 0.05). In Phase 2, the eight patients who received cholestyramine showed an additional decline in free thyroxine from weeks one to two, but the overall rate of decline in hormone levels was not different between the groups. Immunoglobulin levels remained unaffected regardless of group, treatment, or time. CONCLUSIONS We conclude that cholestyramine is a safe and effective adjunctive agent in the treatment of thyrotoxicosis and that its greatest efficacy may be during the first few weeks of treatment. C1 WALTER REED ARMY MED CTR,DEPT CLIN INVEST,WASHINGTON,DC 20307. RP SOLOMON, BL (reprint author), WALTER REED ARMY MED CTR,DEPT MED,ENDOCRINE METAB SERV,ENDOCRINE METAB SERV 7D,WASHINGTON,DC 20307, USA. NR 7 TC 36 Z9 36 U1 0 U2 2 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0300-0664 J9 CLIN ENDOCRINOL JI Clin. Endocrinol. PD JAN PY 1993 VL 38 IS 1 BP 39 EP 43 DI 10.1111/j.1365-2265.1993.tb00970.x PG 5 WC Endocrinology & Metabolism SC Endocrinology & Metabolism GA KG811 UT WOS:A1993KG81100007 PM 8435884 ER PT S AU RICKMAN, WJ MONICAL, C WAXDAL, MJ AF RICKMAN, WJ MONICAL, C WAXDAL, MJ BE Landay, AL Ault, KT Bauer, KD Rabinovitch, PS TI IMPROVED PRECISION IN THE ENUMERATION OF ABSOLUTE NUMBERS OF LYMPHOCYTE PHENOTYPES WITH LONG-TERM MONTHLY PROFICIENCY TESTING SO CLINICAL FLOW CYTOMETRY SE ANNALS OF THE NEW YORK ACADEMY OF SCIENCES LA English DT Proceedings Paper CT CONF ON CLINICAL FLOW CYTOMETRY CY APR 25-28, 1992 CL BALTIMORE, MD SP NEW YORK ACAD SCI, AMAC, HOFFMANN LA ROCHE, PFIZER CENT RES, PHARMINGEN, PHOENIX FLOW SYST RP RICKMAN, WJ (reprint author), WALTER REED ARMY INST RES,DEPT DIAGNOST RETROVIROL,WASHINGTON,DC 20307, USA. NR 0 TC 20 Z9 20 U1 0 U2 0 PU NEW YORK ACAD SCIENCES PI NEW YORK PA NEW YORK SN 0077-8923 BN 0-89766-767-0 J9 ANN NY ACAD SCI JI Ann.NY Acad.Sci. PY 1993 VL 677 BP 53 EP 58 DI 10.1111/j.1749-6632.1993.tb38764.x PG 6 WC Biochemical Research Methods SC Biochemistry & Molecular Biology GA BX95P UT WOS:A1993BX95P00008 PM 8494246 ER PT J AU RUSNAK, JM LUCEY, DR AF RUSNAK, JM LUCEY, DR TI CLINICAL GNATHOSTOMIASIS - CASE-REPORT AND REVIEW OF THE ENGLISH-LANGUAGE LITERATURE SO CLINICAL INFECTIOUS DISEASES LA English DT Review ID EOSINOPHILIC MENINGITIS; EPIDEMIOLOGIC CHARACTERISTICS; NEUROLOGICAL MANIFESTATIONS; ANGIOSTRONGYLUS-CANTONENSIS; URINARY GNATHOSTOMIASIS; CNS INVASION; SPINIGERUM; THAILAND; INFECTION; RADICULOMYELITIS AB Human gnathostomiasis is most frequently caused by the nematode Gnathostoma spinigerum. This disease is endemic to Southeast Asia, particularly Thailand and Japan. The clinical presentation is most commonly characterized by localized, intermittent, migratory swellings of the skin and subcutaneous tissues, often in association with localized pain, pruritus, and erythema. Since this worm can migrate to deeper tissues, any organ system may become involved. Characteristically, patients with gnathostomiasis have a moderate to severe elevation of the peripheral eosinophil count, with values not uncommonly exceeding 50% of the total white blood cell count. With modem-day travel and immigration, cases of gnathostomiasis are being diagnosed with increased frequency in the United States. Because of its rarity in this country, however, gnathostomiasis often is not included in an initial differential diagnosis despite the characteristic triad of intermittent migratory swelling, a history of travel to Southeast Asia, and eosinophilia. We report a case of cutaneous gnathostomiasis diagnosed in the United States, and we present a clinical review of the English-language literature on human gnathostomiasis. C1 WALTER REED ARMY INST RES,DEPT RETROVIRAL RES,WASHINGTON,DC 20307. RP RUSNAK, JM (reprint author), WILFORD HALL USAF MED CTR,SGHMMI,DEPT INFECT DIS,LACKLAND AFB,TX 78236, USA. NR 131 TC 86 Z9 89 U1 2 U2 6 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 1058-4838 J9 CLIN INFECT DIS JI Clin. Infect. Dis. PD JAN PY 1993 VL 16 IS 1 BP 33 EP 50 PG 18 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA KG117 UT WOS:A1993KG11700007 PM 8448317 ER PT J AU TONEY, MAO HEIRONIMUS, JD RIVERA, D HOLLSTEN, D AF TONEY, MAO HEIRONIMUS, JD RIVERA, D HOLLSTEN, D TI SCINTIGRAPHIC EVALUATION OF CORALLINE HYDROXYAPATITE OCULAR IMPLANTS - CASE-REPORTS ON THE USE OF PLANAR AND SPECT BONE-SCINTIGRAPHY SO CLINICAL NUCLEAR MEDICINE LA English DT Article AB Previous reports on the application of bone scintigraphy to evaluate and assess the degree of vascular and soft tissue ingrowth into coralline ocular implants after operation are limited and SPECT imaging has not been reported. Two cases are described in which planar and SPECT imaging of Tc-99m MDP uptake in ocular implants were performed at approximately 3 and 15 months after surgery. C1 BROOKE ARMY MED CTR,DEPT RADIOL,NUCL MED SERV,FT SAM HOUSTON,TX 78234. BROOKE ARMY MED CTR,DEPT SURG,OPHTHALMOL SERV,FT SAM HOUSTON,TX 78234. NR 4 TC 8 Z9 8 U1 0 U2 0 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0363-9762 J9 CLIN NUCL MED JI Clin. Nucl. Med. PD JAN PY 1993 VL 18 IS 1 BP 50 EP 52 PG 3 WC Radiology, Nuclear Medicine & Medical Imaging SC Radiology, Nuclear Medicine & Medical Imaging GA KH240 UT WOS:A1993KH24000012 PM 8380761 ER PT J AU KATZ, N TONEY, MO HEIRONIMUS, JD AF KATZ, N TONEY, MO HEIRONIMUS, JD TI THE EFFECTS OF DANAZOL ON A PATIENT WITH FAMILIAL DYSALBUMINEMIC HYPERTHYROXINEMIA SO CLINICAL NUCLEAR MEDICINE LA English DT Article ID BINDING; EXCESS AB Familial dysalbuminemic hyperthyroxinemia, a syndrome involving an abnormal affinity of albumin for thyroxine, results in elevated total thyroxine and free thyroxine index levels but normal triiodothyronine resin uptake and thyroid-stimulating hormone levels. Danazol is a synthetic androgen that increases triiodothyronine resin uptake and decreases total thyroxine, secondary to a decrease in thyroid-binding globulin levels. A 35-year-old woman with familial dysalbuminemic hyperthyroxinemia who was given danazol, in whom nervousness, insomnia, and weight gain developed, is described. Thyroid tests performed after initiation of danazol therapy revealed an increase in triiodothyronine resin uptake, with persistently elevated total thyroxine and free thyroxine index levels, and normal thyroid-stimulating hormone levels. Once the danazol was withdrawn, the symptoms resolved, the triiodothyronine resin uptake returned to normal, and the thyroid-stimulating hormone remained normal. The effects of danazol on a patient with familial dysalbuminemic hyperthyroxinemia correlate well with the effects on normals, and the ultrasensitive thyroid-stimulating hormone was the most useful test in separating hyperthyroxinemia from hyperthyroidism. RP KATZ, N (reprint author), BROOKE ARMY MED CTR,DEPT RADIOL,NUCL MED SERV,FT SAM HOUSTON,TX 78234, USA. NR 11 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0363-9762 J9 CLIN NUCL MED JI Clin. Nucl. Med. PD JAN PY 1993 VL 18 IS 1 BP 53 EP 55 DI 10.1097/00003072-199301000-00013 PG 3 WC Radiology, Nuclear Medicine & Medical Imaging SC Radiology, Nuclear Medicine & Medical Imaging GA KH240 UT WOS:A1993KH24000013 PM 8422721 ER PT B AU KADIB, A AF KADIB, A BE Hughes, SA TI A VERIFIED MODEL FOR HARBOR ENTRANCE SEDIMENTATION SO COASTAL ENGINEERING CONSIDERATIONS IN COASTAL ZONE MANAGEMENT SE COASTLINES OF THE WORLD LA English DT Proceedings Paper CT SYMP ON COASTAL ENGINEERING CONSIDERATIONS IN COASTAL ZONE MANAGEMENT, AT THE COASTAL ZONE 93 CY 1993 CL NEW ORLEANS, LA SP AMER SHORE & BEACH PRESERVAT ASSOC, AMER SOC CIVIL ENGINEERS, COASTAL ZONE FDN, US DEPT COMMERCE, NATL OCEANIC & ATMOSPHER ADM RP KADIB, A (reprint author), USA CORPS ENGINEERS,COASTAL RES BRANCH,300 N LOS ANGELES ST,LOS ANGELES,CA 90053, USA. NR 0 TC 0 Z9 0 U1 0 U2 1 PU AMER SOC CIVIL ENGINEERS PI NEW YORK PA NEW YORK BN 0-87262-958-9 J9 COASTL WORL PY 1993 BP 93 EP 103 PG 11 WC Engineering, Civil; Oceanography SC Engineering; Oceanography GA BZ17V UT WOS:A1993BZ17V00008 ER PT J AU BERNSTEIN, JS FEIN, A CHOI, JB COOL, TA SAUSA, RC HOWARD, SL LOCKE, RJ MIZIOLEK, AW AF BERNSTEIN, JS FEIN, A CHOI, JB COOL, TA SAUSA, RC HOWARD, SL LOCKE, RJ MIZIOLEK, AW TI LASER-BASED FLAME SPECIES PROFILE MEASUREMENTS - A COMPARISON WITH FLAME MODEL PREDICTIONS SO COMBUSTION AND FLAME LA English DT Article ID SATURATED FLUORESCENCE MEASUREMENTS; ATOMIC-HYDROGEN; AIR FLAMES; SPECTROSCOPY; COMBUSTION; OH; ABSORPTION; MOLECULES; OXYGEN; PULSE AB Two laser-based diagnostic methods, resonance-enhanced multiphoton ionization (REMPI) and laser-induced fluorescence (LIF), were used for relative concentration measurements of seven species, O, H, OH, CH, CO, HCO, and CH3, in low pressure stoichiometric methane/oxygen, ethylene/oxygen, and ethane/oxygen premixed hydrocarbon flames. For the well-understood methane/oxygen flame, measured relative density profiles for these seven species were in good agreement with flame modeling calculations. This agreement justifies the use of the stoichiometric methane/oxygen flame as a standard of comparison by which relative density profiles, measured for other hydrocarbon flames, may be placed on an absolute density scale. This approach was applied to measurements for the ethylene/oxygen and ethane/oxygen flames. Peak HCO densities for these flames appear to be overestimated by model calculations based on current kinetic models of C1 and C2 chemistry. C1 USA,BALLIST RES LABS,ABERDEEN PROVING GROUND,MD 21005. RP BERNSTEIN, JS (reprint author), CORNELL UNIV,SCH APPL & ENGN PHYS,ITHACA,NY 14853, USA. NR 57 TC 49 Z9 51 U1 2 U2 12 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0010-2180 J9 COMBUST FLAME JI Combust. Flame PD JAN PY 1993 VL 92 IS 1-2 BP 85 EP 105 DI 10.1016/0010-2180(93)90200-M PG 21 WC Thermodynamics; Energy & Fuels; Engineering, Multidisciplinary; Engineering, Chemical; Engineering, Mechanical SC Thermodynamics; Energy & Fuels; Engineering GA KD979 UT WOS:A1993KD97900006 ER PT B AU MACUCH, MM AF MACUCH, MM GP IEEE COMMUN SOC TI RANGE EXTENSION VIA SURROGATE SATELLITE SO COMMUNICATIONS ON THE MOVE - MILCOM 93: 1993 IEEE MILITARY COMMUNICATIONS CONFERENCE, CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT 1993 IEEE Military Communications Conference (MILCOM 93): Communications on the Move CY OCT 11-14, 1993 CL BOSTON, MA SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,CTR SIGNAL,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-0953-7 PY 1993 BP 158 EP 161 PG 4 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BZ65D UT WOS:A1993BZ65D00029 ER PT B AU PROCOPIO, VJ BROCKEL, KH INSERRA, JR LOSO, FG MAJOR, PA CHANEY, KD LOCHER, RJ VIGANTS, A RIEHL, M BARNETT, WT AF PROCOPIO, VJ BROCKEL, KH INSERRA, JR LOSO, FG MAJOR, PA CHANEY, KD LOCHER, RJ VIGANTS, A RIEHL, M BARNETT, WT GP IEEE COMMUN SOC TI TACTICAL LINE-OF-SIGHT RADIO PROPAGATION RELIABILITY MODELING SO COMMUNICATIONS ON THE MOVE - MILCOM 93: 1993 IEEE MILITARY COMMUNICATIONS CONFERENCE, CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT 1993 IEEE Military Communications Conference (MILCOM 93): Communications on the Move CY OCT 11-14, 1993 CL BOSTON, MA SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,COMMUN ELECTR COMMAND,SPACE & TERR COMMUN DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-0953-7 PY 1993 BP 609 EP 613 PG 5 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BZ65D UT WOS:A1993BZ65D00116 ER PT B AU BROCKEL, KH INSERRA, JR LOSO, FG MAJOR, PA PROCOPIO, VJ CHANEY, KD LOCHER, RJ VIGANTS, A BARNETT, WT RIEHL, M AF BROCKEL, KH INSERRA, JR LOSO, FG MAJOR, PA PROCOPIO, VJ CHANEY, KD LOCHER, RJ VIGANTS, A BARNETT, WT RIEHL, M GP IEEE COMMUN SOC TI TACTICAL LINE-OF-SIGHT PATH RELIABILITY - PROPAGATION CLIMATE FACTORS SO COMMUNICATIONS ON THE MOVE - MILCOM 93: 1993 IEEE MILITARY COMMUNICATIONS CONFERENCE, CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT 1993 IEEE Military Communications Conference (MILCOM 93): Communications on the Move CY OCT 11-14, 1993 CL BOSTON, MA SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,COMMUN ELECTR COMMAND,SPACE & TERR COMMUN DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-0953-7 PY 1993 BP 614 EP 618 PG 5 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BZ65D UT WOS:A1993BZ65D00117 ER PT B AU BROCKEL, KH CHENG, T MITCHUM, MP AF BROCKEL, KH CHENG, T MITCHUM, MP GP IEEE COMMUN SOC TI NPT - A SUCCESS STORY EVOLVING FROM TEAMWORK AND INNOVATION SO COMMUNICATIONS ON THE MOVE - MILCOM 93: 1993 IEEE MILITARY COMMUNICATIONS CONFERENCE, CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT 1993 IEEE Military Communications Conference (MILCOM 93): Communications on the Move CY OCT 11-14, 1993 CL BOSTON, MA SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,COMMUN ELECTR COMMAND,SPACE & TERR COMMUN DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-0953-7 PY 1993 BP 874 EP 878 PG 5 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BZ65D UT WOS:A1993BZ65D00164 ER PT B AU SILIATO, JM SUDNIKOVICH, WP KENNEDY, LR HALLGRING, RD AF SILIATO, JM SUDNIKOVICH, WP KENNEDY, LR HALLGRING, RD GP IEEE COMMUN SOC TI EVOLVING MODELING AND SIMULATION TECHNOLOGY INTO FIELDABLE PRODUCTS SO COMMUNICATIONS ON THE MOVE - MILCOM 93: 1993 IEEE MILITARY COMMUNICATIONS CONFERENCE, CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT 1993 IEEE Military Communications Conference (MILCOM 93): Communications on the Move CY OCT 11-14, 1993 CL BOSTON, MA SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,COMMUN ELECTR COMMAND,SPACE & TERR COMMUN DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-0953-7 PY 1993 BP 907 EP 911 PG 5 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BZ65D UT WOS:A1993BZ65D00170 ER PT B AU HANRATTY, JM GOWENS, JW EVANS, J RIVERA, B AF HANRATTY, JM GOWENS, JW EVANS, J RIVERA, B GP IEEE COMMUN SOC TI AN EVALUATION OF ISDN VIA ACTS IN SUPPORT OF ARMY WIDE AREA INFORMATION-SERVICES SO COMMUNICATIONS ON THE MOVE - MILCOM 93: 1993 IEEE MILITARY COMMUNICATIONS CONFERENCE, CONFERENCE RECORD, VOLS 1-3 LA English DT Proceedings Paper CT 1993 IEEE Military Communications Conference (MILCOM 93): Communications on the Move CY OCT 11-14, 1993 CL BOSTON, MA SP IEEE, COMMUN SOC, ARMED FORCES COMMUN & ELECTR ASSOC C1 USA,FALLS CHURCH,VA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-0953-7 PY 1993 BP 988 EP 992 PG 5 WC Engineering, Electrical & Electronic; Telecommunications SC Engineering; Telecommunications GA BZ65D UT WOS:A1993BZ65D00186 ER PT S AU OBRIEN, TK SALPEKAR, SA AF OBRIEN, TK SALPEKAR, SA BE Camponeschi, ET TI SCALE EFFECTS ON THE TRANSVERSE TENSILE-STRENGTH OF GRAPHITE-EPOXY COMPOSITES SO COMPOSITE MATERIALS: TESTING AND DESIGN - ELEVENTH VOLUME SE AMERICAN SOCIETY FOR TESTING AND MATERIALS SPECIAL TECHNICAL PUBLICATION LA English DT Proceedings Paper CT 11th Symposium on Composite Materials: Testing and Design CY MAY 04-05, 1992 CL PITTSBURGH, PA SP AMER SOC TESTING & MAT, COMM HIGH MODULUS FIBERS & THEIR COMPOSITES DE COMPOSITE MATERIAL; GRAPHITE EPOXY; TRANSVERSE TENSILE STRENGTH; DELAMINATION; MATRIX CRACK; SCALE LAWS; WEIBULL STATISTICS C1 NASA,LANGLEY RES CTR,USA,RES LAB,VEHICLE STRUCT DIRECTORATE,HAMPTON,VA 23681. NR 0 TC 17 Z9 17 U1 0 U2 2 PU AMERICAN SOCIETY TESTING AND MATERIALS PI W CONSHOHOCKEN PA 100 BARR HARBOR DRIVE, W CONSHOHOCKEN, PA 19428-2959 SN 1071-5827 BN 0-8031-1879-1 J9 AM SOC TEST MATER PY 1993 VL 1206 BP 23 EP 52 PG 30 WC Materials Science, Characterization & Testing; Materials Science, Composites SC Materials Science GA BZ95F UT WOS:A1993BZ95F00002 ER PT S AU GOEKE, EC AF GOEKE, EC BE Camponeschi, ET TI COMPRESSION OF THICK COMPOSITES - 2 TEST METHODS SO COMPOSITE MATERIALS: TESTING AND DESIGN - ELEVENTH VOLUME SE AMERICAN SOCIETY FOR TESTING AND MATERIALS SPECIAL TECHNICAL PUBLICATION LA English DT Proceedings Paper CT 11th Symposium on Composite Materials: Testing and Design CY MAY 04-05, 1992 CL PITTSBURGH, PA SP AMER SOC TESTING & MAT, COMM HIGH MODULUS FIBERS & THEIR COMPOSITES DE ORGANIC MATRIX COMPOSITES; COMPRESSION TESTING C1 USA,RES LAB,MECH MAT BRANCH,WATERTOWN,MA 02172. NR 0 TC 3 Z9 3 U1 0 U2 0 PU AMERICAN SOCIETY TESTING AND MATERIALS PI W CONSHOHOCKEN PA 100 BARR HARBOR DRIVE, W CONSHOHOCKEN, PA 19428-2959 SN 1071-5827 BN 0-8031-1879-1 J9 AM SOC TEST MATER PY 1993 VL 1206 BP 90 EP 102 PG 13 WC Materials Science, Characterization & Testing; Materials Science, Composites SC Materials Science GA BZ95F UT WOS:A1993BZ95F00005 ER PT S AU JACKSON, WC MARTIN, RH AF JACKSON, WC MARTIN, RH BE Camponeschi, ET TI AN INTERLAMINAR TENSILE-STRENGTH SPECIMEN SO COMPOSITE MATERIALS: TESTING AND DESIGN - ELEVENTH VOLUME SE AMERICAN SOCIETY FOR TESTING AND MATERIALS SPECIAL TECHNICAL PUBLICATION LA English DT Proceedings Paper CT 11th Symposium on Composite Materials: Testing and Design CY MAY 04-05, 1992 CL PITTSBURGH, PA SP AMER SOC TESTING & MAT, COMM HIGH MODULUS FIBERS & THEIR COMPOSITES DE COMPOSITE MATERIAL; CARBON EPOXY; INTERLAMINAR TENSILE STRENGTH; CURVED BEAM; DELAMINATION C1 NASA,LANGLEY RES CTR,USA,AEROSTRUCT DIRECTORATE,HAMPTON,VA 23681. NR 0 TC 15 Z9 15 U1 1 U2 2 PU AMERICAN SOCIETY TESTING AND MATERIALS PI W CONSHOHOCKEN PA 100 BARR HARBOR DRIVE, W CONSHOHOCKEN, PA 19428-2959 SN 1071-5827 BN 0-8031-1879-1 J9 AM SOC TEST MATER PY 1993 VL 1206 BP 333 EP 354 PG 22 WC Materials Science, Characterization & Testing; Materials Science, Composites SC Materials Science GA BZ95F UT WOS:A1993BZ95F00022 ER PT J AU HO, H TSAI, MY MORTON, J FARLEY, GL AF HO, H TSAI, MY MORTON, J FARLEY, GL TI A COMPARISON OF 3 POPULAR TEST METHODS FOR DETERMINING THE SHEAR MODULUS OF COMPOSITE-MATERIALS SO COMPOSITES ENGINEERING LA English DT Article ID UNIDIRECTIONAL COMPOSITES AB Three popular shear tests-the 10-degrees off-axis, the +/-45-degrees tensile and the Iosipescu specimen tested in the modified Wyoming fixture-for shear modulus measurement are evaluated for a graphite-epoxy composite material system. A comparison of the shear stress-strain response for each test method is made using conventional strain gage instrumentation and moire interferometry. The uniformity and purity of the strain fields in the test sections of the specimens are discussed, and the shear responses obtained from each test technique are presented and compared. For accurate Measurement of the shear modulus, the 90-degrees Iosipescu specimen is recommended. C1 NASA,LANGLEY RES CTR,USA,AEROSTRUCT DIRECTORATE,HAMPTON,VA 23665. RP HO, H (reprint author), VIRGINIA POLYTECH INST & STATE UNIV,DEPT ENGN SCI & MECH,BLACKSBURG,VA 24061, USA. NR 20 TC 6 Z9 6 U1 1 U2 3 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0961-9526 J9 COMPOS ENG JI Compos. Eng. PY 1993 VL 3 IS 1 BP 69 EP 81 DI 10.1016/0961-9526(93)90032-F PG 13 WC Engineering, Multidisciplinary; Materials Science, Composites SC Engineering; Materials Science GA JN560 UT WOS:A1993JN56000006 ER PT J AU HO, H TSAI, MY MORTON, J FARLEY, GL AF HO, H TSAI, MY MORTON, J FARLEY, GL TI NUMERICAL-ANALYSIS OF THE IOSIPESCU SPECIMEN FOR COMPOSITE-MATERIALS SO COMPOSITES SCIENCE AND TECHNOLOGY LA English DT Article DE NUMERICAL ANALYSIS; COMPOSITE MATERIALS; IOSIPESCU SPECIMEN; SHEAR MODULUS; CORRECTION FACTORS ID SHEAR TEST METHOD; UNIDIRECTIONAL COMPOSITES AB A finite element analysis of the Iosipescu shear test for unidirectional and cross-ply composites is presented. It is shown that an iterative analysis procedure must be used to model the fixture-specimen kinematics. The correction factors which are needed to compensate for the non-uniformity of stress distribution in calculating shear modulus are shown to be dependent on the material orthotropy ratio and the finite element loading models. Test section strain distributions representative of typical graphite/epoxy specimen are also presented. C1 USA,AEROSTRUCT DIRECTORATE,NASA,LANGLEY RES CTR,HAMPTON,VA 23665. RP HO, H (reprint author), VIRGINIA POLYTECH INST & STATE UNIV,DEPT ENGN SCI & MECH,BLACKSBURG,VA 24061, USA. NR 20 TC 35 Z9 35 U1 0 U2 1 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB SN 0266-3538 J9 COMPOS SCI TECHNOL JI Compos. Sci. Technol. PY 1993 VL 46 IS 2 BP 115 EP 128 DI 10.1016/0266-3538(93)90167-F PG 14 WC Materials Science, Composites SC Materials Science GA KH947 UT WOS:A1993KH94700003 ER PT J AU TURCOTTE, LH COMES, BM AF TURCOTTE, LH COMES, BM TI DELIVERING DATA INTERPRETATION - FROM GFLOPS TO INSIGHT SO COMPUTERS & GRAPHICS LA English DT Article AB The quest to deliver computers with teraflop computing power introduces several ancillary technical challenges. One of the most obvious challenges involves the capability to interpret the enormous quantity of data resulting from investigations using today's supercomputers. Data interpretation requires several techniques: printouts, graphics, scientific visualization, and multi-sensory systems. The need to more efficiently interpret large datasets led the US Army Engineers Waterways Experiment Station to establish a scientific visualization center. This center, established in the fall of 1990, provides assistance with the adaptation and implementation of emerging data interpretation techniques to the 800+ researchers at the national laboratory. This paper summarizes the collective experiences of The Center. Experience with commercial visualization software, public domain software, internally developed software, visualization techniques, virtual reality systems, and hardware facilities is presented. C1 USA,CTR SCI VISUALIZAT,USACE WATERWAYS EXPT STN,VICKSBURG,MS 39180. RP TURCOTTE, LH (reprint author), USA,COMP SCI CORP,HIGH PERFORMANCE COMP RES CTR,VICKSBURG,MS 39180, USA. NR 3 TC 2 Z9 2 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0097-8493 J9 COMPUT GRAPH JI Comput. Graph. PD JAN-FEB PY 1993 VL 17 IS 1 BP 23 EP 30 DI 10.1016/0097-8493(93)90048-E PG 8 WC Computer Science, Software Engineering SC Computer Science GA KR462 UT WOS:A1993KR46200005 ER PT B AU HAMILTON, MK KIPP, TA AF HAMILTON, MK KIPP, TA BE Singh, A TI MODEL-BASED MULTISENSOR FUSION SO CONFERENCE RECORD OF THE TWENTY-SEVENTH ASILOMAR CONFERENCE ON SIGNALS, SYSTEMS & COMPUTERS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 27th Asilomar Conference on Signals, Systems and Computers CY NOV 01-03, 1993 CL PACIFIC GROVE, CA SP NAVAL POSTGRAD SCH, SAN JOSE STATE UNIV, IEEE SIGNAL PROC SOC, IEEE COMP SOC C1 USA,RES LAB,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E, COMPUTER SOC PRESS PI LOS ALAMITOS PA 10662 LOS VAQUEROS CIRCLE, LOS ALAMITOS, CA 90720 BN 0-8186-4120-7 PY 1993 BP 283 EP 289 PG 7 WC Computer Science, Artificial Intelligence; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BA17F UT WOS:A1993BA17F00056 ER PT B AU SADLER, BM AF SADLER, BM BE Singh, A TI TEXTURE SEGMENTATION BY CHANGE DETECTION IN 2ND AND HIGHER-ORDER STATISTICS SO CONFERENCE RECORD OF THE TWENTY-SEVENTH ASILOMAR CONFERENCE ON SIGNALS, SYSTEMS & COMPUTERS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 27th Asilomar Conference on Signals, Systems and Computers CY NOV 01-03, 1993 CL PACIFIC GROVE, CA SP NAVAL POSTGRAD SCH, SAN JOSE STATE UNIV, IEEE SIGNAL PROC SOC, IEEE COMP SOC C1 ARMY RES LAB,ADELPHI,MD 20783. NR 0 TC 0 Z9 0 U1 0 U2 1 PU I E E E, COMPUTER SOC PRESS PI LOS ALAMITOS PA 10662 LOS VAQUEROS CIRCLE, LOS ALAMITOS, CA 90720 BN 0-8186-4120-7 PY 1993 BP 436 EP 440 PG 5 WC Computer Science, Artificial Intelligence; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BA17F UT WOS:A1993BA17F00086 ER PT S AU HERZOG, R AF HERZOG, R BE Bond, GC Rooney, JW TI THE ROYAL MARINE AND INSURGENT OPERATIONS IN THE SALAMANCA CAMPAIGN, 1812 SO CONSORTIUM ON REVOLUTIONARY EUROPE 1750-1850, PROCEEDINGS, 1992 SE CONSORTIUM ON REVOLUTIONARY EUROPE 1750-1850 : PROCEEDINGS LA English DT Proceedings Paper CT 22nd Meeting of the Consortium on Revolutionary Europe CY FEB 27-29, 1992 CL AUBURN UNIV, AUBURN, AL SP CONSORTIUM REVOLUT EUROPE HO AUBURN UNIV C1 US MIL ACAD,W POINT,NY 10996. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CONSORTIUM REVOLUTIONARY EUROPE PI BIRMINGHAM PA SAMFORD UNIV, DEPT HISTORY, BIRMINGHAM, AL 35229-0001 SN 0093-2574 J9 CONSORT REVOLUT EUR PY 1993 BP 62 EP 69 PG 8 WC History SC History GA BZ40R UT WOS:A1993BZ40R00008 ER PT J AU HARTFORD, LS AF HARTFORD, LS BE Bond, GC Rooney, JW TI DEFENDING THE FATHERLAND - THE OPERATION OF THE BAVARIAN ARMY DURING THE RATISBON CYCLE, JANUARY-APRIL 1809 SO CONSORTIUM ON REVOLUTIONARY EUROPE 1750-1850, PROCEEDINGS, 1992 SE CONSORTIUM ON REVOLUTIONARY EUROPE 1750-1850 : PROCEEDINGS LA English DT Proceedings Paper CT 22nd Meeting of the Consortium on Revolutionary Europe CY FEB 27-29, 1992 CL AUBURN UNIV, AUBURN, AL SP CONSORTIUM REVOLUT EUROPE HO AUBURN UNIV C1 USA,RESERVE COMMAND,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CONSORTIUM REVOLUTIONARY EUROPE PI BIRMINGHAM PA SAMFORD UNIV, DEPT HISTORY, BIRMINGHAM, AL 35229-0001 SN 0093-2574 J9 CONSORT REVOLUT EUR PY 1993 BP 363 EP 373 DI 10.1520/STP24740S PG 11 WC History SC History GA BZ40R UT WOS:A1993BZ40R00039 ER PT J AU KALASINSKY, KS LEVINE, B SMITH, ML PLATOFF, GE AF KALASINSKY, KS LEVINE, B SMITH, ML PLATOFF, GE TI COMPARISON OF INFRARED AND MASS SPECTROSCOPIES FOR DRUG ANALYSIS SO CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY LA English DT Review DE IR; MS; DRUG ANALYSIS; SPECTROSCOPIC COMPARISONS ID SPECTROMETRY; IR AB Forensic drug testing requires high confidence of identification and low limits of detection. Mass spectroscopy combined with gas chromatography (GC/MS) has typically been the analytical method of choice. To increase the detection capabilities, selected ion monitoring (SIM) has been employed with electron impact (EI) quadrupole MS instruments. This leads to a lower confidence of identification, inasmuch as the full scan is lost. Due to these limitations, alternate mass spectroscopy methods and infrared methods have been explored. Ion trap mass spectrometry reportedly provides the full scan information needed for identification at lower detection limits than full scan quadrupole MS. Methods employing gas chromatography Fourier transform infrared (GC/Fr-IR) spectroscopy provide absolute identification through infrared fingerprinting with routine detection in the parts per billion range. New developments in cryogenic sample deposition for GC/FT-IR have increased the sensitivity of the technique 100 to 1000-fold to match or surpass that of GC/MS. Vapor phase GC/FT-IR has been configured serially with quadrupole MS providing both identification processes with one GC injection, GC/IR/MS. GC/FT-IR methods for vapor phase and cryogenic deposition techniques have been developed for certain drugs and development is continuing for others. C1 USA,FORENS TOXICOL DRUG TESTING LAB,FT GEORGE G MEADE,MD 20755. RP KALASINSKY, KS (reprint author), ARMED FORCES INST PATHOL,OFF ARMED FORCES MED EXAMINER,WASHINGTON,DC 20306, USA. NR 34 TC 9 Z9 9 U1 4 U2 16 PU CRC PRESS INC PI BOCA RATON PA 2000 CORPORATE BLVD NW, JOURNALS CUSTOMER SERVICE, BOCA RATON, FL 33431 SN 1040-8347 J9 CRIT REV ANAL CHEM JI Crit. Rev. Anal. Chem. PY 1993 VL 23 IS 6 BP 441 EP 457 DI 10.1080/10408349308051653 PG 17 WC Chemistry, Analytical SC Chemistry GA KR647 UT WOS:A1993KR64700001 ER PT B AU SKAGGS, LL DAVIS, SA AF SKAGGS, LL DAVIS, SA GP ASSOC STATE FLOODPLAIN MANAGERS TI VARIATIONS IN RESIDENTIAL DEPTH-DAMAGE FUNCTIONS USED BY THE UNITED-STATES-ARMY CORPS-OF-ENGINEERS IN FLOOD DAMAGE ESTIMATION SO CROSS TRAINING: LIGHT THE TORCH LA English DT Proceedings Paper CT 17th Annual Conference of the Association-of-State-Floodplain-Managers - Cross Training, Light the Torch CY MAR 16-18, 1993 CL ATLANTA, GA SP ASSOC STATE FLOODPLAIN MANAGERS C1 USA,CORPS ENGINEERS,INST WATER RESOURCES,FT BELVOIR,VA 22060. NR 0 TC 0 Z9 0 U1 0 U2 0 PU NATURAL HAZARDS RESEARCH & APPLICATIONS INFORMATION CTR PI BOULDER PA INSTITUTE BEHAVIORAL SCIENCE CAMPUS BOX 482 UNIVERSITY COLORADO, BOULDER, CO 80309-0482 PY 1993 BP 49 EP 55 PG 7 WC Engineering, Civil; Environmental Sciences; Water Resources SC Engineering; Environmental Sciences & Ecology; Water Resources GA BB74P UT WOS:A1993BB74P00009 ER PT J AU NAUSCHUETZ, WF HARRISON, LS TREVINO, SB BECKER, GR BENTON, J AF NAUSCHUETZ, WF HARRISON, LS TREVINO, SB BECKER, GR BENTON, J TI 2 RAPID URINE SCREENS FOR DETECTION OF BACTERIURIA - AN EVALUATION SO CURRENT MICROBIOLOGY LA English DT Article ID ANALYZER AB Five hundred twenty-five random clean catch urine specimens, collected from 339 adult females, 137 adult males, and 49 pediatric patients, were screened for the presence of bacteriuria with the Uriscreen catalase test and with the Chemstrip 2 LN dipstick. Quantitative cultures were performed on all specimens. The sensitivity, specificity, positive predictive value, and negative predictive value for the catalase test, with 10(5) CFU/ml as the threshold for significant bacteriuria, were 91.3%, 72.3%, 33.7%, and 98.0%, respectively. Values for the dipstick were 83.9%, 77.9%, 43.7%, and 96.0%. When 10(4) CFU/ml was used as the threshold, the catalase test had a sensitivity of 89.2%, specificity of 70.4%, positive predictive value of 37.3%, and a negative predictive value of 97.0%. Values for the dipstick at that level were 82.3%, 77.5%, 48.6%, and 94.8%. While the catalase test was more sensitive than the dipstick, it was our opinion that high rates of false-negatives associated with these methods negated the convenience of these fast and simple urine screens. RP NAUSCHUETZ, WF (reprint author), BROOKE ARMY MED CTR,DEPT PATHOL & AREA LAB SERV,MICROBIOL SECT,FT SAM HOUSTON,TX 78234, USA. NR 12 TC 3 Z9 3 U1 0 U2 0 PU SPRINGER VERLAG PI NEW YORK PA 175 FIFTH AVE, NEW YORK, NY 10010 SN 0343-8651 J9 CURR MICROBIOL JI Curr. Microbiol. PD JAN PY 1993 VL 26 IS 1 BP 43 EP 45 DI 10.1007/BF01577241 PG 3 WC Microbiology SC Microbiology GA KE283 UT WOS:A1993KE28300007 PM 7763406 ER PT J AU PATTANAPANYASAT, K UDOMSANGPETCH, R WEBSTER, HK AF PATTANAPANYASAT, K UDOMSANGPETCH, R WEBSTER, HK TI 2-COLOR FLOW CYTOMETRIC ANALYSIS OF INTRAERYTHROCYTIC MALARIA PARASITE DNA AND SURFACE MEMBRANE-ASSOCIATED ANTIGEN IN ERYTHROCYTES INFECTED WITH PLASMODIUM-FALCIPARUM SO CYTOMETRY LA English DT Article DE FLUORESCEIN; MALARIA ANTIGEN; NUCLEIC ACID FLUOROCHROME; PROPIDIUM IODIDE; RED BLOOD CELL ID RED-CELLS; EXPRESSION; ANTIBODIES; DIVERSITY AB A method for fixation of Plasmodium falciparum infected erythrocytes and solubilization of the erythrocyte membrane with detergent was developed. This method was applied to two-color flow cytometric analysis of both intraerythrocytic (IE) malaria DNA and parasite-derived antigen on the erythrocyte surface membrane. Infected erythrocytes were fixed with 0.025% glutaraldehyde followed by treatment with 1% saponin to gain access to intramembranous components and allow antibody to interact with antigen. DNA of IE parasite was subsequently stained with propidium iodide. Using this procedure cell morphology was well preserved with excellent parasite DNA staining. Using anti-malaria antibodies which recognize ring-infected erythrocyte surface antigen (Pf155/RESA), we observed that glutaraldehyde-fixed saponin treated infected erythrocytes exhibited a variable immunofluorescence intensity as assessed by both flow cytometry and fluorescence microscopy. Ring-infected cells displayed strong immunofluorescence staining, whereas a weak signal was detected on cells containing schizonts. Simultaneous measurement of parasite DNA and antigen in the infected erythrocyte membrane can facilitate the study of antigen expression in the cell membrane in association with development of IE parasites. C1 MAHIDOL UNIV,FAC SCI,DEPT PATHOBIOL,BANGKOK 10700,THAILAND. ARMED FORCES RES INST MED SCI,DEPT IMMUNOL & BIOCHEM,BANGKOK,THAILAND. RP PATTANAPANYASAT, K (reprint author), SIRIRAJ HOSP,FAC GRAD STUDIES,CTR THALASSEMIA,DIV HEMATOL,BANGKOK 10700,THAILAND. FU NHLBI NIH HHS [HL 34408] NR 26 TC 14 Z9 14 U1 0 U2 1 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0196-4763 J9 CYTOMETRY JI Cytometry PY 1993 VL 14 IS 4 BP 449 EP 454 DI 10.1002/cyto.990140415 PG 6 WC Biochemical Research Methods; Cell Biology SC Biochemistry & Molecular Biology; Cell Biology GA KZ452 UT WOS:A1993KZ45200014 PM 8513699 ER PT S AU NGUYEN, BQ AF NGUYEN, BQ BE Bots, PWG Sol, HG Traunmuller, R TI WORK TIME MEASUREMENT SYSTEM (WTMS) - THE FRONT-END TOOL FOR REDESIGNING THE WORK PROCESS SO DECISION SUPPORT IN PUBLIC ADMINISTRATION SE IFIP TRANSACTIONS A-COMPUTER SCIENCE AND TECHNOLOGY LA English DT Proceedings Paper CT WORKING CONF ON DECISION SUPPORT IN PUBLIC ADMINISTRATION CY MAY 13-14, 1992 CL NOORDWIJKERHOUT, NETHERLANDS SP INT FEDERAT INFORMAT PROC RP NGUYEN, BQ (reprint author), GEORGIA INST TECHNOL,USA,RES LAB,SOFTWARE TECHNOL BRANCH,115 OKEEFE BLDG,ATLANTA,GA 30332, USA. NR 0 TC 0 Z9 0 U1 0 U2 1 PU ELSEVIER SCIENCE PUBL B V PI AMSTERDAM PA AMSTERDAM SN 0926-5473 BN 0-444-81485-X J9 IFIP TRANS A PY 1993 VL 26 BP 111 EP 119 PG 9 WC Public Administration SC Public Administration GA BY43Q UT WOS:A1993BY43Q00009 ER PT J AU BERNER, JK DAULA, TV AF BERNER, JK DAULA, TV TI RECRUITING GOALS, REGIME SHIFTS, AND THE SUPPLY OF LABOR TO THE ARMY SO DEFENCE ECONOMICS LA English DT Article DE MILITARY MANPOWER; SWITCHING SIMULTANEOUS EQUATIONS; YOUTH WAGES; RECRUITING INCENTIVES ID ENLISTMENTS AB This paper extends the existing literature on military-labor supply in three ways. First. using Current Population Survey (CPS) data, it develops a more accurate estimate of the alternative wage faced by young men. Second, it endogenizes the high-quality goal faced by recruiters. As the United States Army Recruiting Command became increasingly better at setting this goal during the 1980's, the assumption that the goal was exogenous to the recruiting process became increasingly suspect. This paper presents evidence that the goal is indeed endogenous. Finally, it presents estimates based on a switching simultaneous-equations statistical specfication that allows behavior to vary across recruiting environments to reflect the asymmetric incentives faced by recruiters. The findings show that the estimates of the parameters with the greatest policy content are sensitive to each of these specification issues. C1 US MIL ACAD,DEPT SOCIAL SCI,W POINT,NY 10996. OEOB,COUNCIL ECON ADVISORS,WASHINGTON,DC 20008. NR 22 TC 5 Z9 5 U1 0 U2 1 PU HARWOOD ACAD PUBL GMBH PI READING PA C/O STBS LTD, PO BOX 90, READING, BERKS, ENGLAND RG1 8JL SN 1043-0717 J9 DEFENC ECON PY 1993 VL 4 IS 4 BP 315 EP 338 DI 10.1080/10430719308404771 PG 24 WC Economics SC Business & Economics GA MD907 UT WOS:A1993MD90700002 ER PT B AU SAMPSON, JB AF SAMPSON, JB GP HUMAN FACTORS & ERGON SOC TI COGNITIVE PERFORMANCE OF INDIVIDUALS USING A HEAD-MOUNTED DISPLAY WHILE WALKING SO DESIGNING FOR DIVERSITY, VOLS 1 AND 2 LA English DT Proceedings Paper CT Human-Factors-and-Ergomonics-Society 37th Annual Meeting: Designing for Diversity CY OCT 11-15, 1993 CL SEATTLE, WA SP HUMAN FACTORS & ERGON SOC C1 USA,NATICK RD&E CTR,NATICK,MA 01760. NR 0 TC 6 Z9 6 U1 0 U2 0 PU HUMAN FACTORS AND ERGONOMICS SOC PI SANTA MONICA PA PO BOX 1369, SANTA MONICA, CA 90406-1369 PY 1993 BP 338 EP 342 PG 5 WC Ergonomics; Multidisciplinary Sciences SC Engineering; Science & Technology - Other Topics GA BZ48S UT WOS:A1993BZ48S00069 ER PT B AU HAAS, EC CASALI, JG AF HAAS, EC CASALI, JG GP HUMAN FACTORS & ERGON SOC TI THE PERCEIVED URGENCY AND DETECTION TIME OF MULTITONE AND FREQUENCY-MODULATED WARNING SIGNALS SO DESIGNING FOR DIVERSITY, VOLS 1 AND 2 LA English DT Proceedings Paper CT Human-Factors-and-Ergomonics-Society 37th Annual Meeting: Designing for Diversity CY OCT 11-15, 1993 CL SEATTLE, WA SP HUMAN FACTORS & ERGON SOC C1 USA,RES LAB,HUMAN RES & ENGN DIRECTORATE,AUDITORY PROC TEAM,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 0 PU HUMAN FACTORS AND ERGONOMICS SOC PI SANTA MONICA PA PO BOX 1369, SANTA MONICA, CA 90406-1369 PY 1993 BP 544 EP 548 PG 5 WC Ergonomics; Multidisciplinary Sciences SC Engineering; Science & Technology - Other Topics GA BZ48S UT WOS:A1993BZ48S00111 ER PT J AU SHARP, M RICE, V NINDL, B WILLIAMSON, T AF SHARP, M RICE, V NINDL, B WILLIAMSON, T GP HUMAN FACTORS & ERGON SOC TI MAXIMUM LIFTING CAPACITY IN SINGLE AND MIXED GENDER 3-PERSON TEAMS SO DESIGNING FOR DIVERSITY, VOLS 1 AND 2 LA English DT Proceedings Paper CT Human-Factors-and-Ergomonics-Society 37th Annual Meeting: Designing for Diversity CY OCT 11-15, 1993 CL SEATTLE, WA SP HUMAN FACTORS & ERGON SOC C1 USA,ENVIRONM MED RES INST,NATICK,MA 01760. NR 0 TC 0 Z9 0 U1 0 U2 0 PU HUMAN FACTORS AND ERGONOMICS SOC PI SANTA MONICA PA PO BOX 1369, SANTA MONICA, CA 90406-1369 PY 1993 BP 725 EP 729 PG 5 WC Ergonomics; Multidisciplinary Sciences SC Engineering; Science & Technology - Other Topics GA BZ48S UT WOS:A1993BZ48S00146 ER PT B AU KELLEHER, JH COURY, BG AF KELLEHER, JH COURY, BG GP HUMAN FACTORS & ERGON SOC TI THE INFLUENCE OF PERSONALITY IN THE PROCESSING OF DISPLAY FORMATS SO DESIGNING FOR DIVERSITY, VOLS 1 AND 2 LA English DT Proceedings Paper CT Human-Factors-and-Ergomonics-Society 37th Annual Meeting: Designing for Diversity CY OCT 11-15, 1993 CL SEATTLE, WA SP HUMAN FACTORS & ERGON SOC C1 US MIL ACAD,W POINT,NY 10996. NR 0 TC 1 Z9 1 U1 0 U2 0 PU HUMAN FACTORS AND ERGONOMICS SOC PI SANTA MONICA PA PO BOX 1369, SANTA MONICA, CA 90406-1369 PY 1993 BP 910 EP 914 PG 5 WC Ergonomics; Multidisciplinary Sciences SC Engineering; Science & Technology - Other Topics GA BZ48S UT WOS:A1993BZ48S00181 ER PT B AU MELIZA, LL AF MELIZA, LL GP HUMAN FACTORS & ERGON SOC TI MEASURING THE PERFORMANCE OF ARMOR PLATOONS IN THE SIMNET ENVIRONMENT SO DESIGNING FOR DIVERSITY, VOLS 1 AND 2 LA English DT Proceedings Paper CT Human-Factors-and-Ergomonics-Society 37th Annual Meeting: Designing for Diversity CY OCT 11-15, 1993 CL SEATTLE, WA SP HUMAN FACTORS & ERGON SOC C1 USA,RES INST,FIELD UNIT,ORLANDO,FL. NR 0 TC 0 Z9 0 U1 0 U2 0 PU HUMAN FACTORS AND ERGONOMICS SOC PI SANTA MONICA PA PO BOX 1369, SANTA MONICA, CA 90406-1369 PY 1993 BP 1186 EP 1190 PG 5 WC Ergonomics; Multidisciplinary Sciences SC Engineering; Science & Technology - Other Topics GA BZ48S UT WOS:A1993BZ48S00229 ER PT B AU LOCKHART, JM STRUB, MH HAWLEY, JK TAPIA, LA AF LOCKHART, JM STRUB, MH HAWLEY, JK TAPIA, LA GP HUMAN FACTORS & ERGON SOC TI AUTOMATION AND SUPERVISORY CONTROL - A PERSPECTIVE ON HUMAN-PERFORMANCE, TRAINING, AND PERFORMANCE AIDING SO DESIGNING FOR DIVERSITY, VOLS 1 AND 2 LA English DT Proceedings Paper CT Human-Factors-and-Ergomonics-Society 37th Annual Meeting: Designing for Diversity CY OCT 11-15, 1993 CL SEATTLE, WA SP HUMAN FACTORS & ERGON SOC C1 USA,RES INST,FIELD UNIT,FT BLISS,TX. NR 0 TC 1 Z9 1 U1 0 U2 0 PU HUMAN FACTORS AND ERGONOMICS SOC PI SANTA MONICA PA PO BOX 1369, SANTA MONICA, CA 90406-1369 PY 1993 BP 1211 EP 1215 PG 5 WC Ergonomics; Multidisciplinary Sciences SC Engineering; Science & Technology - Other Topics GA BZ48S UT WOS:A1993BZ48S00234 ER PT B AU BIRKMIRE, DP KARSH, R BARNETTE, BD PILLALAMARRI, R DIBASTIANI, S AF BIRKMIRE, DP KARSH, R BARNETTE, BD PILLALAMARRI, R DIBASTIANI, S GP HUMAN FACTORS & ERGON SOC TI EYE-MOVEMENTS IN SEARCH AND TARGET ACQUISITION SO DESIGNING FOR DIVERSITY, VOLS 1 AND 2 LA English DT Proceedings Paper CT Human-Factors-and-Ergomonics-Society 37th Annual Meeting: Designing for Diversity CY OCT 11-15, 1993 CL SEATTLE, WA SP HUMAN FACTORS & ERGON SOC C1 USA,HUMAN RES & ENGN DIRECTORATE,RES LAB,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 0 Z9 0 U1 0 U2 0 PU HUMAN FACTORS AND ERGONOMICS SOC PI SANTA MONICA PA PO BOX 1369, SANTA MONICA, CA 90406-1369 PY 1993 BP 1305 EP 1309 PG 5 WC Ergonomics; Multidisciplinary Sciences SC Engineering; Science & Technology - Other Topics GA BZ48S UT WOS:A1993BZ48S00251 ER PT B AU KINGSLEY, LE PASTORE, R SINGH, H LITZ, MS BEHR, S CREEDON, J AF KINGSLEY, LE PASTORE, R SINGH, H LITZ, MS BEHR, S CREEDON, J BE Prestwich, KR Baker, WL TI 100-KV, 1-KHZ BLUMLEIN PULSER FOR MICROWAVE APPLICATIONS SO DIGEST OF TECHNICAL PAPERS - NINTH IEEE INTERNATIONAL PULSED POWER CONFERENCE, VOLS 1 AND 2 LA English DT Proceedings Paper CT 9th IEEE International Pulsed Power Conference CY JUN 21-23, 1993 CL ALBUQUERQUE, NM SP IEEE, ELECTRON DEVICES SOC, IEEE, NUCL & PLASMA SCI SOC C1 USA,RES LAB,CTR PULSE POWEER,AMSRL EP MC,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1416-6 PY 1993 BP 95 EP 98 PG 4 WC Engineering, Electrical & Electronic; Engineering, Mechanical; Physics, Fluids & Plasmas SC Engineering; Physics GA BC61N UT WOS:A1993BC61N00023 ER PT B AU PODLESAK, TF FONDA, K CREEDON, J ULRICH, R AF PODLESAK, TF FONDA, K CREEDON, J ULRICH, R BE Prestwich, KR Baker, WL TI A COMPARATIVE EXPERIMENTAL STUDY OF CAPACITOR DIELECTRICS UNDER RINGING CONDITIONS SO DIGEST OF TECHNICAL PAPERS - NINTH IEEE INTERNATIONAL PULSED POWER CONFERENCE, VOLS 1 AND 2 LA English DT Proceedings Paper CT 9th IEEE International Pulsed Power Conference CY JUN 21-23, 1993 CL ALBUQUERQUE, NM SP IEEE, ELECTRON DEVICES SOC, IEEE, NUCL & PLASMA SCI SOC C1 USA,RES LAB,PULSE POWER COMPONENTS BRANCH,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1416-6 PY 1993 BP 261 EP 264 PG 4 WC Engineering, Electrical & Electronic; Engineering, Mechanical; Physics, Fluids & Plasmas SC Engineering; Physics GA BC61N UT WOS:A1993BC61N00066 ER PT B AU PASTORE, R WEINER, M SINGH, H SCHNEIDER, S FOX, R AYRES, G AF PASTORE, R WEINER, M SINGH, H SCHNEIDER, S FOX, R AYRES, G BE Prestwich, KR Baker, WL TI EVALUATION OF SCRS AS MILLISECOND SWITCHES FOR ELECTRIC GUN LAUNCHERS SO DIGEST OF TECHNICAL PAPERS - NINTH IEEE INTERNATIONAL PULSED POWER CONFERENCE, VOLS 1 AND 2 LA English DT Proceedings Paper CT 9th IEEE International Pulsed Power Conference CY JUN 21-23, 1993 CL ALBUQUERQUE, NM SP IEEE, ELECTRON DEVICES SOC, IEEE, NUCL & PLASMA SCI SOC C1 USA,RES LAB,PULSE POWER COMPONENTS BRANCH,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1416-6 PY 1993 BP 360 EP 363 PG 4 WC Engineering, Electrical & Electronic; Engineering, Mechanical; Physics, Fluids & Plasmas SC Engineering; Physics GA BC61N UT WOS:A1993BC61N00090 ER PT B AU KIM, A YOUMANS, R WEINER, M JASPER, L AF KIM, A YOUMANS, R WEINER, M JASPER, L BE Prestwich, KR Baker, WL TI PHOTOCONDUCTIVE FREQUENCY AGILE GAAS IMPULSE DEVICE SO DIGEST OF TECHNICAL PAPERS - NINTH IEEE INTERNATIONAL PULSED POWER CONFERENCE, VOLS 1 AND 2 LA English DT Proceedings Paper CT 9th IEEE International Pulsed Power Conference CY JUN 21-23, 1993 CL ALBUQUERQUE, NM SP IEEE, ELECTRON DEVICES SOC, IEEE, NUCL & PLASMA SCI SOC C1 USA,RES LAB,EPSD,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1416-6 PY 1993 BP 407 EP 410 PG 4 WC Engineering, Electrical & Electronic; Engineering, Mechanical; Physics, Fluids & Plasmas SC Engineering; Physics GA BC61N UT WOS:A1993BC61N00102 ER PT B AU KATULKA, GL DELGUERCIO, M KHONG, T AF KATULKA, GL DELGUERCIO, M KHONG, T BE Prestwich, KR Baker, WL TI APPLICATIONS OF DIGITAL AND OPTOELECTRONIC CIRCUITS TO ELECTROTHERMAL-CHEMICAL GUN SYSTEM FACILITIES SO DIGEST OF TECHNICAL PAPERS - NINTH IEEE INTERNATIONAL PULSED POWER CONFERENCE, VOLS 1 AND 2 LA English DT Proceedings Paper CT 9th IEEE International Pulsed Power Conference CY JUN 21-23, 1993 CL ALBUQUERQUE, NM SP IEEE, ELECTRON DEVICES SOC, IEEE, NUCL & PLASMA SCI SOC C1 USA RES LAB,WEAPONS TECHNOL DIRECTORATE,DIV PROPULS & FLIGHT,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1416-6 PY 1993 BP 546 EP 549 PG 4 WC Engineering, Electrical & Electronic; Engineering, Mechanical; Physics, Fluids & Plasmas SC Engineering; Physics GA BC61N UT WOS:A1993BC61N00136 ER PT B AU KATULKA, GL KHONG, TN BURDEN, H WHITE, K AF KATULKA, GL KHONG, TN BURDEN, H WHITE, K BE Prestwich, KR Baker, WL TI MEASUREMENT TECHNIQUES IN A 30-MM ELECTROTHERMAL-CHEMICAL (ETC) GUN FACILITY SO DIGEST OF TECHNICAL PAPERS - NINTH IEEE INTERNATIONAL PULSED POWER CONFERENCE, VOLS 1 AND 2 LA English DT Proceedings Paper CT 9th IEEE International Pulsed Power Conference CY JUN 21-23, 1993 CL ALBUQUERQUE, NM SP IEEE, ELECTRON DEVICES SOC, IEEE, NUCL & PLASMA SCI SOC C1 USA RES LAB,WEAPONS TECHNOL DIRECTORATE,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1416-6 PY 1993 BP 550 EP 553 PG 4 WC Engineering, Electrical & Electronic; Engineering, Mechanical; Physics, Fluids & Plasmas SC Engineering; Physics GA BC61N UT WOS:A1993BC61N00137 ER PT B AU LUU, K CHANG, D CORADESCHI, T HILDENBRAND, D RAPKA, J AF LUU, K CHANG, D CORADESCHI, T HILDENBRAND, D RAPKA, J BE Prestwich, KR Baker, WL TI DESIGN AND TEST RESULTS OF A THERMALLY FUSED EXPLOSIVE SWITCH SO DIGEST OF TECHNICAL PAPERS - NINTH IEEE INTERNATIONAL PULSED POWER CONFERENCE, VOLS 1 AND 2 LA English DT Proceedings Paper CT 9th IEEE International Pulsed Power Conference CY JUN 21-23, 1993 CL ALBUQUERQUE, NM SP IEEE, ELECTRON DEVICES SOC, IEEE, NUCL & PLASMA SCI SOC C1 USA,CTR ARMAMENT RES DEV & ENGN,DIV ELECT ARMAMENTS,PICATINNY ARSENAL,NJ 07806. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1416-6 PY 1993 BP 587 EP 589 PG 3 WC Engineering, Electrical & Electronic; Engineering, Mechanical; Physics, Fluids & Plasmas SC Engineering; Physics GA BC61N UT WOS:A1993BC61N00146 ER PT B AU BURKE, T PODLESAK, TF CARTER, J FELTZ, R AF BURKE, T PODLESAK, TF CARTER, J FELTZ, R BE Prestwich, KR Baker, WL TI INVESTIGATION OF NOVEL CAPACITORS FOR PULSE POWER APPLICATIONS SO DIGEST OF TECHNICAL PAPERS - NINTH IEEE INTERNATIONAL PULSED POWER CONFERENCE, VOLS 1 AND 2 LA English DT Proceedings Paper CT 9th IEEE International Pulsed Power Conference CY JUN 21-23, 1993 CL ALBUQUERQUE, NM SP IEEE, ELECTRON DEVICES SOC, IEEE, NUCL & PLASMA SCI SOC C1 USA,RES LAB,PULSE POWER COMPONENTS BRANCH,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1416-6 PY 1993 BP 751 EP 753 PG 3 WC Engineering, Electrical & Electronic; Engineering, Mechanical; Physics, Fluids & Plasmas SC Engineering; Physics GA BC61N UT WOS:A1993BC61N00188 ER PT B AU PASTORE, R PODLESAK, TF SINGH, H FONDA, K CREEDON, J AF PASTORE, R PODLESAK, TF SINGH, H FONDA, K CREEDON, J BE Prestwich, KR Baker, WL TI PROGRESS IN 2N MEGAJOULE ELECTROTHERMAL CHEMICAL GUN PULSER SO DIGEST OF TECHNICAL PAPERS - NINTH IEEE INTERNATIONAL PULSED POWER CONFERENCE, VOLS 1 AND 2 LA English DT Proceedings Paper CT 9th IEEE International Pulsed Power Conference CY JUN 21-23, 1993 CL ALBUQUERQUE, NM SP IEEE, ELECTRON DEVICES SOC, IEEE, NUCL & PLASMA SCI SOC C1 USA,RES LAB,PULSE POWER COMPONENTS BRANCH,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1416-6 PY 1993 BP 783 EP 786 PG 4 WC Engineering, Electrical & Electronic; Engineering, Mechanical; Physics, Fluids & Plasmas SC Engineering; Physics GA BC61N UT WOS:A1993BC61N00196 ER PT B AU PODLESAK, TF SINGH, H FONDA, K CREEDON, J SCHOFIELD, GL JOHNSON, FO AF PODLESAK, TF SINGH, H FONDA, K CREEDON, J SCHOFIELD, GL JOHNSON, FO BE Prestwich, KR Baker, WL TI MEGAWATT HIGH SPEED SOLID STATE CIRCUIT BREAKER FOR PULSE POWER APPLICATIONS SO DIGEST OF TECHNICAL PAPERS - NINTH IEEE INTERNATIONAL PULSED POWER CONFERENCE, VOLS 1 AND 2 LA English DT Proceedings Paper CT 9th IEEE International Pulsed Power Conference CY JUN 21-23, 1993 CL ALBUQUERQUE, NM SP IEEE, ELECTRON DEVICES SOC, IEEE, NUCL & PLASMA SCI SOC C1 USA,RES LAB,PULSE POWER COMPONENTS BRANCH,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1416-6 PY 1993 BP 984 EP 987 PG 4 WC Engineering, Electrical & Electronic; Engineering, Mechanical; Physics, Fluids & Plasmas SC Engineering; Physics GA BC61N UT WOS:A1993BC61N00252 ER PT J AU DANIEL, FB ROBINSON, M OLSON, GR YORK, RG CONDIE, LW AF DANIEL, FB ROBINSON, M OLSON, GR YORK, RG CONDIE, LW TI 10-DAY AND 90-DAY TOXICITY STUDIES OF 2-CHLOROPHENOL IN SPRAGUE-DAWLEY RATS SO DRUG AND CHEMICAL TOXICOLOGY LA English DT Article ID CHLORINATED PHENOLS AB Male and female Sprague-Dawley rats received 2-chlorophenol in corn oil daily by gavage for 10 or 90 consecutive days. The 1 0-day study doses were 13, 64, 129 and 257 mg/kg while the 90-day subchronic study doses were 17, 50 and 150 mg/kg. In the 10-day study, hematologic and clinical chemistry, food and water consumption, absolute and relative organ weights, and histopathological findings revealed no compound or sex-related effects. In the 90-day study there were no significant gross or histopathological findings that were treatment-related in either sex. There were statistically significant differences between control and treated groups associated with hematology, clinical chemistry and organ weights; however, none of the differences were considered to be biologically meaningful. C1 PATHOL ASSOCIATES INC,W CHESTER,OH 45069. USA,DUGWAY PROVING GROUND,DIV LIFE SCI,DUGWAY PROVING GROUND,UT 84022. RP DANIEL, FB (reprint author), US EPA,ENVIRONM MONITORING SYST LAB,DIV ECOL MONITORING RES,CINCINNATI,OH 45268, USA. NR 32 TC 0 Z9 0 U1 1 U2 2 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0148-0545 J9 DRUG CHEM TOXICOL JI Drug Chem. Toxicol. PY 1993 VL 16 IS 3 BP 277 EP 291 PG 15 WC Chemistry, Multidisciplinary; Pharmacology & Pharmacy; Toxicology SC Chemistry; Pharmacology & Pharmacy; Toxicology GA LQ185 UT WOS:A1993LQ18500004 PM 8404547 ER PT J AU DANIEL, FB ROBINSON, M OLSON, GR YORK, RG CONDIE, LW AF DANIEL, FB ROBINSON, M OLSON, GR YORK, RG CONDIE, LW TI 10-DAY AND 90-DAY TOXICITY STUDIES OF 2,4-DIMETHYLPHENOL IN SPRAGUE-DAWLEY RATS SO DRUG AND CHEMICAL TOXICOLOGY LA English DT Article AB Male and female Sprague-Dawley rats received 2,4-dimethylphenol daily by gavage for 10 or 90 consecutive days. The 10-day acute study doses were 0, 60, 120, 600 and 1200 mg/kg; the 90-day subchronic study doses were 0, 60, 180 and 540 mg/kg. Corn oil was used as the vehicle. In the 10-day study, all the high dose animals died. At 600 mg/kg there was a significant increase in relative liver weight in females and several significant alterations in hematologic and clinical chemistry values in both sexes. Histopathological examination revealed changes associated with the forestomach in all dose groups. The gel-day study had numerous compound-related deaths at the 540 mg/kg level. In addition, the final body weight in high close males and females was significantly less while absolute lung weights and relative liver weights in females, and relative brain, kidney and testes weights in males were also altered. Significant clinical chemistry findings in high dose animals (540 mg/kg) included reduced creatinine and increased cholesterol in both sexes, with increased triglycerides and decreased AST in males only. Histopathologic evaluation revealed hyperkeratosis and epithelial hyperplasia of the forestomach in males and females in the middle and high-dose groups. C1 PATHOL ASSOCIATES INC,W CHESTER,OH 45069. USA,DUGWAY PROVING GROUND,DIV LIFE SCI,DUGWAY PROVING GROUND,UT 84022. RP DANIEL, FB (reprint author), US EPA,ENVIRONM MONITORING SYST LAB,DIV ECOL MONITORING RES,CINCINNATI,OH 45268, USA. NR 23 TC 1 Z9 1 U1 1 U2 1 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0148-0545 J9 DRUG CHEM TOXICOL JI Drug Chem. Toxicol. PY 1993 VL 16 IS 4 BP 351 EP 368 DI 10.3109/01480549308998226 PG 18 WC Chemistry, Multidisciplinary; Pharmacology & Pharmacy; Toxicology SC Chemistry; Pharmacology & Pharmacy; Toxicology GA MZ868 UT WOS:A1993MZ86800003 PM 8281889 ER PT J AU LEVY, A DACHIR, S KADAR, T SHUKITTHALE, B STILLMAN, MJ LIEBERMAN, HR AF LEVY, A DACHIR, S KADAR, T SHUKITTHALE, B STILLMAN, MJ LIEBERMAN, HR TI NIMODIPINE, STRESS, AND CENTRAL CHOLINERGIC FUNCTION SO DRUGS IN DEVELOPMENT LA English DT Proceedings Paper CT Investigators Meeting on CA2-Plus Antagonists in the Central Nervous System CY APR 01-04, 1992 CL SANTA FE, NM SP MILES INST PRECLIN PHARM DE ACETYLCHOLINE (ACH); ACQUISITION; ALTITUDE; CA1; CA3; CHOLINERGIC SYSTEM; CORTICOSTERONE; HYPOBARIC HYPOXIA; HIPPOCAMPUS; LEARNING; MEMORY; MICRODIALYSIS; NIMODIPINE; RADIAL ARM MAZE; STRESS ID WORKING MEMORY; NERVOUS-SYSTEM; AGING RABBITS; DYSFUNCTION; HIPPOCAMPUS; BRAIN; YOUNG; RATS C1 ISRAEL INST BIOL RES,IL-70450 NESS ZIONA,ISRAEL. USA,ENVIRONM MED RES INST,NATICK,MA 01760. NR 26 TC 3 Z9 3 U1 0 U2 0 PU NEVA PRESS PI BRANFORD PA P O BOX 347, BRANFORD, CT 06405 SN 1066-7008 J9 DRUG DEV JI Drug. Dev. PY 1993 VL 2 BP 223 EP 229 PG 7 GA MV625 UT WOS:A1993MV62500024 ER PT J AU WASSERMAN, EA YUEN, DA RUSTAD, JR AF WASSERMAN, EA YUEN, DA RUSTAD, JR TI MOLECULAR-DYNAMICS STUDY OF THE TRANSPORT-PROPERTIES OF PEROVSKITE MELTS UNDER HIGH-TEMPERATURE AND PRESSURE CONDITIONS SO EARTH AND PLANETARY SCIENCE LETTERS LA English DT Article ID MGSIO3 PEROVSKITE; SHEAR VISCOSITY; SILICATE; LIQUID; GLASS; COMPRESSION; SIMULATIONS; EQUATION; SPECTRA; STATE AB The transport properties of perovskite melts by molecular dynamics in the temperature range from 3000 to 6000 K and pressure range from 5.1 to 78 GPa were studied. Shear viscosities, coefficients of self-diffusion, infrared absorption spectra, and vibrational densities of states were calculated. Shear viscosities were computed through generalized mean-squared displacement of momenta. Shear viscosity estimates ranged from 3 x 10(-2) to 5 x 10(-2) P and did not vary significantly with temperature. The activation energy found for shear viscosity was about 38 kJ/mol. Our results showed that the Stokes-Einstein relationship between shear viscosity and self-diffusion did not hold. Activation energies of 139, 184, and 166 kJ/mol found for self-diffusion of Mg, Si and 0 atoms, respectively, at 5 GPa agree with experimental estimates. For P > 15 GPa and T = 4500 K, activation volumes of 4.9, 2.9 and 1.3 cm3 were found. The main peaks of the infrared spectrum are shifted towards lower frequencies with increasing pressure, while the peak frequency of the density of states moves up for higher pressures. The shift of infrared absorption peaks is due to coordination changes of the silicon atoms from four- to five-fold and six-fold and has been observed experimentally. Changes of Si from four-fold coordination at P = 5 GPa to five- and six-fold coordinations at high pressure around 70 GPa were found. C1 UNIV MINNESOTA,MINNESOTA SUPERCOMP INST,DEPT GEOL & GEOPHYS,1200 WASHINGTON AVE S,MINNEAPOLIS,MN 55455. UNIV MINNESOTA,MINNESOTA SUPERCOMP INST,ARMY HIGH PERFORMANCE COMP RES CTR,MINNEAPOLIS,MN 55455. NR 39 TC 24 Z9 24 U1 0 U2 4 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0012-821X J9 EARTH PLANET SC LETT JI Earth Planet. Sci. Lett. PD JAN PY 1993 VL 114 IS 2-3 BP 373 EP 384 DI 10.1016/0012-821X(93)90037-A PG 12 WC Geochemistry & Geophysics SC Geochemistry & Geophysics GA KK958 UT WOS:A1993KK95800012 ER PT B AU TASCHEK, WG BISHOP, ND AF TASCHEK, WG BISHOP, ND GP AMER CHEM SOC TI PRIMARY POWER UNIT (PPU) FOR HIGHLY MOBILE ELECTRONIC SHELTER SYSTEMS SO ENERGY ENVIRONMENT ECONOMICS: 28TH INTERSOCIETY ENERGY CONVERSION ENGINEERING CONFERENCE PROCEEDINGS (IECEC-93), VOL 2: ENVIRONMENTAL IMPACT, ENERGY SYSTEMS, NEW TECHNOLOGY FOR ENERGY UTILIZATION, POLICY ISSUES, RENEWABLE ENERGY SOURCES, STIRLING CYCLES LA English DT Proceedings Paper CT 28th Intersociety Energy Conversion Engineering Conference (IECEC-93) CY AUG 08-13, 1993 CL ATLANTA, GA SP AMER CHEM SOC, AMER INST AERONAUT & ASTRONAUT, AMER SOC MECH ENGINEERS, IEEE, AMER INST CHEM ENGINEERS, AMER NUCL SOC, SOC AUTOMOT ENGINEERS C1 USA,CTR RD&E,LOGIST EQUIPMENT DIRECTORATE,FT BELVOIR,VA 22060. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 SIXTEENTH ST NW, WASHINGTON, DC 20036 BN 0-8412-2772-5 PY 1993 BP 263 EP 266 PG 4 WC Engineering, Aerospace; Energy & Fuels; Engineering, Mechanical; Environmental Sciences SC Engineering; Energy & Fuels; Environmental Sciences & Ecology GA BZ61T UT WOS:A1993BZ61T00041 ER PT J AU WANG, YY CHIANG, FP BARSOUM, RS CHOU, ST AF WANG, YY CHIANG, FP BARSOUM, RS CHOU, ST TI STUDY OF DEFORMATION FIELD OF INTERFACE CRACK IN ADHESIVE JOINT SO ENGINEERING FRACTURE MECHANICS LA English DT Article ID SPECIMENS AB Moire interferometry has been applied to a study of the deformation field of an interface crack between an adhesive layer and a composite adherend. A sandwich end-notched flexure is tested. Both normal and tangential components of the crack-face displacement jump are estimated. The stress intensity factor, which is determined by the displacement jump of the crack face, is evaluated at both macro- and microscopic scales. The analysis is based on the plane stress assumption, although three dimensional deformation in the vicinity of the crack tip is evident. C1 USA,MAT TECHNOL LAB,WATERTOWN,MA 02172. RP WANG, YY (reprint author), SUNY STONY BROOK,DEPT MECH ENGN,STONY BROOK,NY 11794, USA. NR 11 TC 4 Z9 4 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0013-7944 J9 ENG FRACT MECH JI Eng. Fract. Mech. PD JAN PY 1993 VL 44 IS 2 BP 175 EP 184 DI 10.1016/0013-7944(93)90042-Q PG 10 WC Mechanics SC Mechanics GA KJ812 UT WOS:A1993KJ81200002 ER PT J AU RASDORF, WJ SPAINHOUR, LK PATTON, EM BURNS, BP AF RASDORF, WJ SPAINHOUR, LK PATTON, EM BURNS, BP TI A DESIGN ENVIRONMENT FOR LAMINATED FIBER-REINFORCED THICK COMPOSITE-MATERIALS SO ENGINEERING WITH COMPUTERS LA English DT Article DE COMPOSITE MATERIALS; COMPOSITES; COMPUTER-AIDED DESIGN; COMPUTER INTEGRATED MANUFACTURING; DATABASE; DESIGN DATABASE; MATERIAL PROPERTY DATABASE AB The research described herein concerns the integration of several components of engineering software using a relational database. More specifically, a conceptual finite element material preprocessing system for laminated fiber-reinforced thick composite materials is studied. In this computer-aided analysis (CAA) system, a materials database is integrated with several software components, including commercially available finite element analysis (FEA) programs and preprocessors, and tools for the design of laminated composite materials. The system focuses on assembling, manipulating and using composite materials data, resulting in the transfer of 2-D and 3-D composite materials property data into a finite element analysis program. The system is life-cycle in nature, supporting a composite through testing, analysis and design. It offers great versatility in its ability to use raw ply data from any source, design layups, and generate laminate properties and FEA materials data files. Despite the fact that such integrated systems are not new in many domains, they have not been successfully introduced to the realm of composite materials analysis and design. This outcome is due largely to the nature of the materials themselves and the overhead they bring to the development of a successful life-cycle model. C1 USA,BALLIST RES LABS,MECH & STRUCT BRANCH,ABERDEEN PROVING GROUND,MD 21005. RP RASDORF, WJ (reprint author), N CAROLINA STATE UNIV,DEPT CIVIL ENGN,RALEIGH,NC 27695, USA. NR 19 TC 0 Z9 0 U1 0 U2 2 PU SPRINGER VERLAG PI NEW YORK PA 175 FIFTH AVE, NEW YORK, NY 10010 SN 0177-0667 J9 ENG COMPUT JI Eng. Comput. PY 1993 VL 9 IS 1 BP 36 EP 48 DI 10.1007/BF01198252 PG 13 WC Computer Science, Interdisciplinary Applications; Engineering, Mechanical SC Computer Science; Engineering GA LJ720 UT WOS:A1993LJ72000004 ER PT S AU BRANDON, DL LEE, CR SIMMERS, JW SKOGERBOE, JG WILHELM, GS AF BRANDON, DL LEE, CR SIMMERS, JW SKOGERBOE, JG WILHELM, GS BE Vernet, J TI LONG-TERM EVALUATION OF PLANTS AND ANIMALS COLONIZING CONTAMINATED DREDGED MATERIAL PLACED IN UPLAND AND WETLAND ENVIRONMENTS SO ENVIRONMENTAL CONTAMINATION SE STUDIES IN ENVIRONMENTAL SCIENCE LA English DT Proceedings Paper CT 5th International Conference on Environmental Contamination CY SEP 29-OCT 01, 1992 CL MORGES, SWITZERLAND C1 USA,ENGINEER WATERWAYS EXPT STN,ENVIRONM LAB,VICKSBURG,MS 39180. NR 0 TC 1 Z9 1 U1 0 U2 0 PU ELSEVIER SCIENCE PUBL B V PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0166-1116 BN 0-444-89868-9 J9 STUD ENVIRON SCI PY 1993 VL 55 BP 231 EP 258 PG 28 WC Environmental Sciences; Geology SC Environmental Sciences & Ecology; Geology GA BZ43Z UT WOS:A1993BZ43Z00013 ER PT S AU LEE, CR SIMMERS, JW BRANDON, DL ONEIL, LJ CULLINANE, MJ ROBERTSON, JM AF LEE, CR SIMMERS, JW BRANDON, DL ONEIL, LJ CULLINANE, MJ ROBERTSON, JM BE Vernet, J TI THE IMPORTANCE OF BIOLOGICAL TESTING IN THE ASSESSMENT OF METAL CONTAMINATION AND SITE REMEDIATION SO ENVIRONMENTAL CONTAMINATION SE STUDIES IN ENVIRONMENTAL SCIENCE LA English DT Proceedings Paper CT 5th International Conference on Environmental Contamination CY SEP 29-OCT 01, 1992 CL MORGES, SWITZERLAND C1 USA,ENGINEER WATERWAYS EXPT STN,ENVIRONM LAB,VICKSBURG,MS 39180. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ELSEVIER SCIENCE PUBL B V PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0166-1116 BN 0-444-89868-9 J9 STUD ENVIRON SCI PY 1993 VL 55 BP 293 EP 301 PG 9 WC Environmental Sciences; Geology SC Environmental Sciences & Ecology; Geology GA BZ43Z UT WOS:A1993BZ43Z00015 ER PT J AU RUBEL, GO ZIMMERMANN, CJ AF RUBEL, GO ZIMMERMANN, CJ TI A NOVEL METHOD FOR MEASURING THE EVAPORATION OF CONTAMINANT LIQUIDS FROM SANDS SO ENVIRONMENTAL POLLUTION LA English DT Article ID ADSORPTION AB A novel experimental system, electrodynamic levitation, is used to measure the evaporation of liquids from microparticles of sand The levitator is used to measure the evaporation rate of diethylphthalate (DEP) from microparticles of Saudi Arabian sand at 1 atm pressure and 25-degrees-C Evaporation experiments were conducted for both inland- and coastal-sand microparticles, the diameter of which is 50 mum. The DEP-evaporation rate is determined from gravimetric changes in the DEP-sand-mixture particle, the weight of which is directly proportional to the levitating electric-field intensity. From telemicroscopical observations, it is found that, when the sand particle is enclosed in DEP liquid, the sand-DEP-mixture particle evaporates like a pure DEP droplet. However, when sufficient DEP liquid has evaporated and the DEP is adsorbed into the sand microparticle, the DEP evaporation rate is reduced by a factor of 3-5 as compared with a pure DP droplet. C1 GEOCENTERS INC,FT WASHINGTON,MD 20744. RP RUBEL, GO (reprint author), USA,ARMAMENT MUNIT & CHEM COMMAND,CTR CHEM RES DEV & ENGN,ABERDEEN PROVING GROUND,MD 21010, USA. NR 6 TC 1 Z9 1 U1 0 U2 0 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB SN 0269-7491 J9 ENVIRON POLLUT JI Environ. Pollut. PY 1993 VL 81 IS 2 BP 157 EP 161 DI 10.1016/0269-7491(93)90081-X PG 5 WC Environmental Sciences SC Environmental Sciences & Ecology GA LL678 UT WOS:A1993LL67800010 PM 15091825 ER PT S AU DILLON, TM AF DILLON, TM BE Gorsuch, JW Dwyer, FJ Ingersoll, CG LaPoint, TW TI DEVELOPING CHRONIC SUBLETHAL SEDIMENT BIOASSAYS - A CHALLENGE TO THE SCIENTIFIC COMMUNITY SO ENVIRONMENTAL TOXICOLOGY AND RISK ASSESSMENT: 2ND VOLUME SE AMERICAN SOCIETY FOR TESTING AND MATERIALS SPECIAL TECHNICAL PUBLICATION LA English DT Proceedings Paper CT Symposium on Environmental Toxicology and Risk Assessment: Aquatic, Plant, and Terrestrial CY APR 26-30, 1992 CL PITTSBURGH, PA SP AMER SOC TESTING & MAT, COMM BIOL EFFECTS & ENVIRONM FATE DE CHRONIC; SUBLETHAL; SEDIMENT; BIOASSAY; GROWTH; REPRODUCTION; POPULATION DYNAMICS; DEMOGRAPHIC MODELS C1 ENVIRONM LAB,CEWES ES R,USAE WATERWAYS EXPT STN,VICKSBURG,MS 39180. NR 0 TC 4 Z9 4 U1 0 U2 0 PU AMERICAN SOCIETY TESTING AND MATERIALS PI W CONSHOHOCKEN PA 100 BARR HARBOR DRIVE, W CONSHOHOCKEN, PA 19428-2959 SN 1071-5827 BN 0-8031-1485-0 J9 AM SOC TEST MATER PY 1993 VL 1216 BP 623 EP 639 DI 10.1520/STP13181S PG 17 WC Public, Environmental & Occupational Health; Toxicology SC Public, Environmental & Occupational Health; Toxicology GA BZ53R UT WOS:A1993BZ53R00041 ER PT S AU LEE, CR SIMMERS, JW BRANDON, DL FOLSOM, BL AF LEE, CR SIMMERS, JW BRANDON, DL FOLSOM, BL BE Gorsuch, JW Dwyer, FJ Ingersoll, CG LaPoint, TW TI THE IMPORTANCE OF BIOLOGICAL TESTING IN THE ASSESSMENT OF METAL CONTAMINATION AND SITE REMEDIATION - A CASE-STUDY SO ENVIRONMENTAL TOXICOLOGY AND RISK ASSESSMENT: 2ND VOLUME SE AMERICAN SOCIETY FOR TESTING AND MATERIALS SPECIAL TECHNICAL PUBLICATION LA English DT Proceedings Paper CT Symposium on Environmental Toxicology and Risk Assessment: Aquatic, Plant, and Terrestrial CY APR 26-30, 1992 CL PITTSBURGH, PA SP AMER SOC TESTING & MAT, COMM BIOL EFFECTS & ENVIRONM FATE DE BIOASSAYS; METAL CONTAMINATION; SITE REMEDIATION; EARTHWORMS; CLAMS; CYPERUS-ESCULENTUS; PLANTS; SOIL CONTAMINATION C1 USA,ENGINEER WATERWAYS EXPT STN,ENVIRONM LAB,VICKSBURG,MS 39180. NR 0 TC 1 Z9 1 U1 0 U2 0 PU AMERICAN SOCIETY TESTING AND MATERIALS PI W CONSHOHOCKEN PA 100 BARR HARBOR DRIVE, W CONSHOHOCKEN, PA 19428-2959 SN 1071-5827 BN 0-8031-1485-0 J9 AM SOC TEST MATER PY 1993 VL 1216 BP 681 EP 687 DI 10.1520/STP13184S PG 7 WC Public, Environmental & Occupational Health; Toxicology SC Public, Environmental & Occupational Health; Toxicology GA BZ53R UT WOS:A1993BZ53R00044 ER PT J AU KRYWICKI, RF FIGUEROA, JA JACKSON, JG KOZELSKY, TW SHIMASAKI, S VONHOFF, DD YEE, D AF KRYWICKI, RF FIGUEROA, JA JACKSON, JG KOZELSKY, TW SHIMASAKI, S VONHOFF, DD YEE, D TI REGULATION OF INSULIN-LIKE GROWTH-FACTOR BINDING-PROTEINS IN OVARIAN-CANCER CELLS BY ESTROGEN SO EUROPEAN JOURNAL OF CANCER LA English DT Article ID HUMAN-SKIN FIBROBLASTS; MOLECULAR-CLONING; BREAST-CANCER; FACTOR-I; EXPRESSION; IDENTIFICATION; RECEPTOR; RAT; DETERMINANTS; IGFBPS AB Insulin-like growth factor-I (IGF-I), its receptor and its binding proteins are expressed by ovarian cancer cells. In this study, we examined oestradiol (E(2)) regulation of IGF-I and IGF binding proteins (IGFBP) in an oestrogen-responsive ovarian cancer cell line, PE04. In serum-free conditions, PE04 cell monolayer growth was increased 1.64-fold by 3 nmol/l E(2) compared with controls, although IGF-I mRNA levels were not increased. In contrast to IGF-I mRNA, IGFBP mRNA was regulated by E(2). E(2) caused a marked decrease in IGFBP-3 RNA, but IGFBP-2, -4 and -6 levels were only minimally depressed. IGFBP-5 mRNA levels were increased by E(2). Tamoxifen had less effect on IGFBP mRNA regulation. Ligand blotting showed that E(2) reduced IGFBP levels in conditioned media. IGFBP RNA was also detected in human ovarian tissue samples. Thus, IGFBP expression can be regulated in oestrogen-responsive ovarian cancer by E(2). C1 UNIV TEXAS,HLTH SCI CTR,DEPT MED,DIV MED ONCOL,SAN ANTONIO,TX 78284. BROOKE ARMY MED CTR,HEMATOL ONCOL SERV,FT SAM HOUSTON,TX 78234. WHITTIER INST DIABET & ENDOCRINOL,LA JOLLA,CA 92037. FU NCI NIH HHS [CA-52592, P30 CA54174, CA-09434] NR 30 TC 31 Z9 31 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0959-8049 J9 EUR J CANCER JI Eur. J. Cancer PY 1993 VL 29A IS 14 BP 2015 EP 2019 DI 10.1016/0959-8049(93)90464-Q PG 5 WC Oncology SC Oncology GA ME854 UT WOS:A1993ME85400023 PM 7506561 ER PT B AU Miller, GA AF Miller, GA BE Rogers, E TI Video 101 - A video media primer SO EXCHANGING CAPITAL IDEAS LA English DT Proceedings Paper CT 1993 National Interpreters Workshop on Exchanging Capital Ideas CY NOV 17-22, 1993 CL WASHINGTON, DC SP Natl Assoc Interpretat DE interactive video; videodisc; LCD video projection; digital; analog C1 USA,CORPS ENGINEERS,KANSAS CITY,MO 64106. NR 0 TC 0 Z9 0 U1 0 U2 0 PU NATIONAL ASSOCIATION INTERPRETATION PI FT COLLINS PA PO BOX 1892, FT COLLINS, CO 80522 PY 1993 BP 237 EP 240 PG 4 WC Education & Educational Research SC Education & Educational Research GA BE83W UT WOS:A1993BE83W00065 ER PT J AU KIM, HJ TAUB, IA AF KIM, HJ TAUB, IA TI INTRINSIC CHEMICAL MARKERS FOR ASEPTIC PROCESSING OF PARTICULATE FOODS SO FOOD TECHNOLOGY LA English DT Article ID LOW-ACID FOODS; THERMAL-PROCESSES; HEAT-TRANSFER; KINETICS; PRODUCT; SYSTEM RP KIM, HJ (reprint author), USA,NATICK RES DEV & ENGN CTR,FOOD ENGN DIRECTORAT,DIV TECHNOL ACQUIS,NATICK,MA 01760, USA. NR 37 TC 37 Z9 39 U1 0 U2 2 PU INST FOOD TECHNOLOGISTS PI CHICAGO PA SUITE 300 221 N LASALLE ST, CHICAGO, IL 60601-1291 SN 0015-6639 J9 FOOD TECHNOL-CHICAGO JI Food Technol. PD JAN PY 1993 VL 47 IS 1 BP 91 EP & PG 0 WC Food Science & Technology SC Food Science & Technology GA KH508 UT WOS:A1993KH50800013 ER PT B AU SEGAN, EG KURATH, P AF SEGAN, EG KURATH, P BE Rossmanith, HP TI ENVIRONMENTAL-FACTORS FOR POSTTENSIONING MATERIALS IN CONCRETE STRUCTURES SO FRACTURE AND DAMAGE OF CONCRETE AND ROCK FDCR-2 (VIENNA, 1992) LA English DT Proceedings Paper CT 2nd International Conference on Fracture and Damage of Concrete and Rock (FDCR-2) CY NOV 09-13, 1992 CL VIENNA, AUSTRIA SP TECH UNIV VIENNA, INT UNION TESTING & RES LABS MAT & STRUCT, AUSTRIAN FED ECON CHAMBER, WIFI, GERMAN ASSOC MAT RES & TESTING, SWISS SOC MAT TECHNOL, AUSTRIAN ASSOC MAT TESTING, AUSTRIAN FED SOC ENGINEERS & ARCHITECTS DE ENVIRONMENTALLY ASSISTED CRACKING; HIGH STRENGTH STEELS; STRESS CORROSION CRACKING; HYDROGEN EMBRITTLEMENT; POSTTENSIONING SYSTEMS C1 USA,CONSTRUCT ENGN RES LABS,CHAMPAIGN,IL. NR 0 TC 0 Z9 0 U1 0 U2 0 PU E & FN SPON PI LONDON PA 2-6 BOUNDARY ROW, LONDON, ENGLAND SE1 8HN BN 0-419-18470-8 PY 1993 BP 107 EP 121 PG 15 WC Construction & Building Technology; Materials Science, Multidisciplinary; Mechanics SC Construction & Building Technology; Materials Science; Mechanics GA BA26L UT WOS:A1993BA26L00009 ER PT B AU LOPEZ, LR SMITH, RE AF LOPEZ, LR SMITH, RE BE Meyer, JA Roitblat, HL Wilson, SW TI EVOLVING ARTIFICIAL INSECT BRAINS FOR ARTIFICIAL COMPOUND EYE ROBOTICS SO FROM ANIMALS TO ANIMATS 2: PROCEEDINGS OF THE SECOND INTERNATIONAL CONFERENCE ON SIMULATION OF ADAPTIVE BEHAVIOR SE COMPLEX ADAPTIVE SYSTEMS LA English DT Proceedings Paper CT 2nd International Conference on Simulation of Adaptive Behavior: From Animals to Animats 2 (SAB92) CY DEC 07-11, 1992 CL HONOLULU, HI SP USAF, OFF SCI RES, DEF ADV RES PROJECTS AGCY, MINIST EDUC NATL & CULTURE, USN, OFF NAVAL RES C1 USA,SPACE & STRATEG DEF COMMAND,DIV COMP RESOURCES HARDWARE,HUNTSVILLE,AL 35807. NR 0 TC 0 Z9 0 U1 0 U2 0 PU M I T PRESS PI CAMBRIDGE PA 55 HAYWARD ST, CAMBRIDGE, MA 02142 BN 0-262-63149-0 J9 COM ADAP SY PY 1993 BP 425 EP 430 PG 6 WC Automation & Control Systems; Behavioral Sciences; Computer Science, Artificial Intelligence; Computer Science, Cybernetics; Neurosciences; Psychology, Experimental SC Automation & Control Systems; Behavioral Sciences; Computer Science; Neurosciences & Neurology; Psychology GA BA26G UT WOS:A1993BA26G00050 ER PT S AU ORISTIAN, JE POST, JE AF ORISTIAN, JE POST, JE BE Grayson, LP TI INCORPORATING ANALOG INTEGRATED-CIRCUITS IN THE UNDERGRADUATE CURRICULUM SO FRONTIERS IN EDUCATION - PROCEEDINGS, 23RD ANNUAL CONFERENCE: ENGINEERING EDUCATION: RENEWING AMERICAS TECHNOLOGY SE PROCEEDINGS-FRONTIERS IN EDUCATION CONFERENCE LA English DT Proceedings Paper CT 23rd Annual Frontiers in Education Conference: Engineering Education - Renewing Americas Technology CY NOV 06-09, 1993 CL WASHINGTON, DC SP IEEE, EDUC SOC, AMER SOC ENGN EDUC, EDUC RES & METHODS DIV C1 US MIL ACAD,W POINT,NY 10996. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 SN 0190-5848 BN 0-7803-1482-4 J9 PROC FRONT EDUC CONF PY 1993 BP 573 EP 577 DI 10.1109/FIE.1993.405459 PG 5 WC Education, Scientific Disciplines; Engineering, Multidisciplinary SC Education & Educational Research; Engineering GA BZ72A UT WOS:A1993BZ72A00116 ER PT S AU REICH, DE ALFORD, KL AF REICH, DE ALFORD, KL BE Grayson, LP TI USING E-MAIL AS A TEACHING ASSISTANT SO FRONTIERS IN EDUCATION - PROCEEDINGS, 23RD ANNUAL CONFERENCE: ENGINEERING EDUCATION: RENEWING AMERICAS TECHNOLOGY SE PROCEEDINGS-FRONTIERS IN EDUCATION CONFERENCE LA English DT Meeting Abstract CT 23rd Annual Frontiers in Education Conference: Engineering Education - Renewing Americas Technology CY NOV 06-09, 1993 CL WASHINGTON, DC SP IEEE, EDUC SOC, AMER SOC ENGN EDUC, EDUC RES & METHODS DIV C1 US MIL ACAD,W POINT,NY 10996. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 SN 0190-5848 BN 0-7803-1482-4 J9 PROC FRONT EDUC CONF PY 1993 BP 846 EP 846 DI 10.1109/FIE.1993.405387 PG 1 WC Education, Scientific Disciplines; Engineering, Multidisciplinary SC Education & Educational Research; Engineering GA BZ72A UT WOS:A1993BZ72A00187 ER PT S AU PISCITELLE, LJ AF PISCITELLE, LJ BE Christiansen, PL Eilbeck, JC Parmentier, RK TI DYNAMICAL-SYSTEMS ANALYSIS OF AN AERODYNAMIC DECELERATOR - BIFURCATION TO DIVERGENCE AND FLUTTER SO FUTURE DIRECTIONS OF NONLINEAR DYNAMICS IN PHYSICAL AND BIOLOGICAL SYSTEMS SE NATO ADVANCED SCIENCE INSTITUTES SERIES, SERIES B, PHYSICS LA English DT Proceedings Paper CT NATO Advanced Study Institute on Future Directions of Nonlinear Dynamics in Physical and Biological Systems, in honor of Alwyn Scotts 60th Birthday CY JUL 23-AUG 01, 1992 CL TU DENMARK, LYNGBY, DENMARK SP NATO, SCI & ENVIRONM AFFAIRS DIV, USA LAB COMMAND, ARMY RES OFF, USA EUROPEAN RES OFF, NATL SCI FDN, DANISH TECH RES COUNCIL, TU DENMARK HO TU DENMARK C1 USA,NATICK RES DEV & ENGN CTR,AEROMECH ENGN DIRECTORATE,NATICK,MA 01760. NR 0 TC 1 Z9 1 U1 0 U2 0 PU PLENUM PRESS DIV PLENUM PUBLISHING CORP PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 SN 0258-1221 BN 0-306-44562-X J9 NATO ADV SCI INST SE PY 1993 VL 312 BP 161 EP 164 PG 4 WC Mechanics; Physics, Mathematical SC Mechanics; Physics GA BZ61J UT WOS:A1993BZ61J00027 ER PT J AU ANGUEIRA, C KADAKIA, S AF ANGUEIRA, C KADAKIA, S TI ESOPHAGEAL AND DUODENAL BEZOARS FROM PERDIEM SO GASTROINTESTINAL ENDOSCOPY LA English DT Letter ID SUCRALFATE; IMPACTION C1 BROOKE ARMY MED CTR,DEPT MED,SAN ANTONIO,TX. RP ANGUEIRA, C (reprint author), BROOKE ARMY MED CTR,GASTROENTEROL SERV,SAN ANTONIO,TX, USA. NR 11 TC 9 Z9 9 U1 0 U2 0 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0016-5107 J9 GASTROINTEST ENDOSC JI Gastrointest. Endosc. PD JAN-FEB PY 1993 VL 39 IS 1 BP 110 EP 111 DI 10.1016/S0016-5107(93)70038-3 PG 2 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA KP814 UT WOS:A1993KP81400038 PM 8454137 ER PT B AU HENRY, KS CHRISTOPHER, BR AF HENRY, KS CHRISTOPHER, BR GP IND FABRICS ASSOC INT TI PAVEMENT TEST SECTION TO DETERMINE THE EFFECT OF GEOTEXTILE ON FROST HEAVE SO GEOSYNTHETICS '93 - CONFERENCE PROCEEDINGS, VOLS 1-3 LA English DT Proceedings Paper CT Geosynthetics 93 Conference CY MAR 30-APR 01, 1993 CL VANCOUVER, CANADA SP N AMER GEOSYNTHET SOC, IND FABR ASSOC INT, INT GEOTEXTILE SOC C1 USA,COLD REG RES & ENGN LAB,HANOVER,NH 03755. NR 0 TC 0 Z9 0 U1 0 U2 0 PU INDUSTRIAL FABRICS ASSOC INT PI ST PAUL PA 345 CEDAR BUILDING, SUITE 450, ST PAUL, MN 55101 PY 1993 BP 95 EP 108 PG 14 WC Engineering, Civil; Materials Science, Textiles SC Engineering; Materials Science GA BC02Y UT WOS:A1993BC02Y00008 ER PT B AU CALDWELL, DR GRAFF, LH AF CALDWELL, DR GRAFF, LH GP AMER CONGRESS SURVEYING & MAPPING TI DIRECTIONAL REGIONS IN GEOGRAPHIC INFORMATION-SYSTEMS (GIS) SO GIS/LIS '93 PROCEEDINGS, VOL 1 LA English DT Proceedings Paper CT GIS/LIS '93 Annual Conference & Exposition CY NOV 02-04, 1993 CL MINNEAPOLIS, MN SP AMER CONGRESS SURVEYING & MAPPING, AMER SOC PHOTOGRAMMETRY & REMOTE SENSING, AM FM INT, ASSOC AMER GEOGRAPHERS, URBAN & REG INFORMAT SYST ASSOC C1 USA,CTR TOPOGRAPH ENGN,DIV AUTONOMOUS TECHNOL,FT BELVOIR,VA 22060. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC PHOTOGRAMMETRY & REMOTE SENSING PI BETHESDA PA 5410 GROSVENOR LAND, SUITE 210, BETHESDA, MD 20814-2160 BN 0-944426-99-9 PY 1993 BP 83 EP 91 PG 9 WC Geography; Information Science & Library Science; Urban Studies SC Geography; Information Science & Library Science; Urban Studies GA BZ99B UT WOS:A1993BZ99B00013 ER PT B AU MITASOVA, H BROWN, W GERDES, DP KOSINOVSKY, I BAKER, T AF MITASOVA, H BROWN, W GERDES, DP KOSINOVSKY, I BAKER, T GP AMER CONGRESS SURVEYING & MAPPING TI MULTIDIMENSIONAL INTERPOLATION, ANALYSIS AND VISUALIZATION FOR ENVIRONMENTAL MODELING SO GIS/LIS '93 PROCEEDINGS, VOL 2 LA English DT Proceedings Paper CT GIS/LIS '93 Annual Conference & Exposition CY NOV 02-04, 1993 CL MINNEAPOLIS, MN SP AMER CONGRESS SURVEYING & MAPPING, AMER SOC PHOTOGRAMMETRY & REMOTE SENSING, AM FM INT, ASSOC AMER GEOGRAPHERS, URBAN & REG INFORMAT SYST ASSOC C1 USA,CONSTRUCT ENGN RES LABS,SPATIAL ANAL & SYST TEAM,CHAMPAIGN,IL 61826. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC PHOTOGRAMMETRY & REMOTE SENSING PI BETHESDA PA 5410 GROSVENOR LAND, SUITE 210, BETHESDA, MD 20814-2160 BN 1-57083-000-2 PY 1993 BP 550 EP 556 PG 7 WC Geography; Information Science & Library Science; Urban Studies SC Geography; Information Science & Library Science; Urban Studies GA BZ99A UT WOS:A1993BZ99A00012 ER PT J AU JEFFORD, CW VELARDE, JA BERNARDINELLI, G BRAY, DH WARHURST, DC MILHOUS, WK AF JEFFORD, CW VELARDE, JA BERNARDINELLI, G BRAY, DH WARHURST, DC MILHOUS, WK TI SYNTHESIS, STRUCTURE, AND ANTIMALARIAL ACTIVITY OF TRICYCLIC 1,2,4-TRIOXANES RELATED TO ARTEMISININ SO HELVETICA CHIMICA ACTA LA English DT Article ID PLASMODIUM-FALCIPARUM; DRUG-RESISTANCE; INVITRO; PYRIMETHAMINE; ARTEANNUIN AB Two sets of tricyclic 1,2,4-trioxanes containing the ABC (10, 11) and ACD ring portions (21, 22, 32, 33, 37, and 38) of artemisinin (1) were synthesized by successive photo-oxygenation of appropriate enol-ether precursors to 1,2-dioxanes and inter- and intramolecular reaction with a carbonyl compound or oxo-substituted side-chain. The structures of 10, 21, and 22 were determined by X-ray analysis. The anti-malarial activity of all trioxanes, except 37 and 38, was evaluated in vitro against chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum parasites. Trioxanes 11 and 21 were as active as artemisinin (1). It was found that neither the lactone function nor rings B and D of 1 were essential for activity. A possible pharmacophore for artemisinin-like activity, which embodies a spirocyclopentane group attached to C(3) of 1,2,4-trioxane, was proposed. C1 UNIV LONDON LONDON SCH HYG & TROP MED,PHLS MALARIA REFERENCE LAB,LONDON WC1E 7HT,ENGLAND. WALTER REED ARMY INST RES,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307. RP JEFFORD, CW (reprint author), UNIV GENEVA,DEPT ORGAN CHEM,CH-1211 GENEVA 4,SWITZERLAND. NR 40 TC 72 Z9 73 U1 1 U2 5 PU NEW SWISS CHEMICAL SOC PI BASEL PA VERLAG HELVETICA CHIMICA ACTA, MALZGASSE 21, POSTFACH 313, CH-4010 BASEL, SWITZERLAND SN 0018-019X J9 HELV CHIM ACTA JI Helv. Chim. Acta PY 1993 VL 76 IS 8 BP 2775 EP 2788 DI 10.1002/hlca.19930760804 PG 14 WC Chemistry, Multidisciplinary SC Chemistry GA MN649 UT WOS:A1993MN64900003 ER PT J AU COLEMAN, MB ADAMS, JG WALKER, AM PLONCZYNSKI, MW HARRELL, AH KARK, JA SCHECHTER, GP AF COLEMAN, MB ADAMS, JG WALKER, AM PLONCZYNSKI, MW HARRELL, AH KARK, JA SCHECHTER, GP TI HB SAN-DIEGO [BETA-109(G11)VAL-]MET] IN AN IRANIAN - FURTHER EVIDENCE FOR A MUTATIONAL HOT-SPOT AT POSITION 109 OF THE BETA-GLOBIN GENE SO HEMOGLOBIN LA English DT Note ID VARIANT; DNA C1 VET ADM MED CTR,JACKSON,MS 39216. UNIV MISSISSIPPI,MED CTR,SCH MED,DEPT MED,JACKSON,MS 39216. WALTER REED ARMY INST RES,DEPT MED,WASHINGTON,DC 20307. VET ADM MED CTR,WASHINGTON,DC 20422. NR 8 TC 2 Z9 2 U1 0 U2 0 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0363-0269 J9 HEMOGLOBIN JI Hemoglobin PY 1993 VL 17 IS 6 BP 543 EP 545 DI 10.3109/03630269309043494 PG 3 WC Biochemistry & Molecular Biology; Hematology SC Biochemistry & Molecular Biology; Hematology GA MN449 UT WOS:A1993MN44900005 PM 8144354 ER PT B AU LETHERWOOD, MD GUNTER, DD WEHAGE, RA AF LETHERWOOD, MD GUNTER, DD WEHAGE, RA BE Tentner, AM TI FIELD VALIDATION OF HIGH-RESOLUTION COMPUTER-BASED HMMWV AND HIGH-MOBILITY TRAILER (HMT) ANALYTICAL MODELS SO HIGH PERFORMANCE COMPUTING SYMPOSIUM 1993: GRAND CHALLENGES IN COMPUTER SIMULATION LA English DT Proceedings Paper CT 1993 Simulation Multiconference features the 1st High Performance Computing Symposium: Grand Challenges in Computer Simulation CY MAR 29-APR 01, 1993 CL ARLINGTON, VA SP SOC COMP SIMULAT C1 USA,CTR TANK AUTOMOT RES DEV & ENGN,DIV SYST SIMULAT & TECHNOL,WARREN,MI 48397. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 BN 1-56555-052-8 PY 1993 BP 220 EP 230 PG 11 WC Computer Science, Interdisciplinary Applications SC Computer Science GA BA16Z UT WOS:A1993BA16Z00034 ER PT B AU EILER, MK HOOGTERP, FB AF EILER, MK HOOGTERP, FB BE Tentner, AM TI VISUALIZATION METHODS FOR SUSPENSION SYSTEM-DESIGN SO HIGH PERFORMANCE COMPUTING SYMPOSIUM 1993: GRAND CHALLENGES IN COMPUTER SIMULATION LA English DT Proceedings Paper CT 1993 Simulation Multiconference features the 1st High Performance Computing Symposium: Grand Challenges in Computer Simulation CY MAR 29-APR 01, 1993 CL ARLINGTON, VA SP SOC COMP SIMULAT C1 USA,TANK AUTOMOT COMMAND,CTR MOBIL TECHNOL,WARREN,MI 48397. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 BN 1-56555-052-8 PY 1993 BP 237 EP 242 PG 6 WC Computer Science, Interdisciplinary Applications SC Computer Science GA BA16Z UT WOS:A1993BA16Z00036 ER PT J AU KIMMEL, RH AF KIMMEL, RH TI NOTES ON THE CULTURAL ORIGINS AND FUNCTIONS OF SUB-FLOOR PITS SO HISTORICAL ARCHAEOLOGY LA English DT Article RP KIMMEL, RH (reprint author), US ARMY CORPS ENGINEERS,ENVIRONM RESOURCES BRANCH,POB 1890,WILMINGTON,NC 28402, USA. NR 40 TC 5 Z9 5 U1 0 U2 0 PU SOC HISTORICAL ARCHAEOLOGY PI TUCSON PA PO BOX 30446, TUCSON, AZ 85751-0446 SN 0440-9213 J9 HIST ARCHAEOL JI Hist. Archaeol. PY 1993 VL 27 IS 3 BP 102 EP 113 PG 12 WC Archaeology SC Archaeology GA MG084 UT WOS:A1993MG08400006 ER PT S AU FRIEDL, KE VOGEL, JA MARCHITELLI, LJ KUBEL, SL AF FRIEDL, KE VOGEL, JA MARCHITELLI, LJ KUBEL, SL BE Ellis, KJ Eastman, JD TI ASSESSMENT OF REGIONAL BODY-COMPOSITION CHANGES BY DUAL-ENERGY X-RAY ABSORPTIOMETRY SO HUMAN BODY COMPOSITION: IN VIVO METHODS, MODELS, AND ASSESSMENT SE BASIC LIFE SCIENCES LA English DT Proceedings Paper CT International Symposium on In Vivo Body Composition Studies CY NOV 10-12, 1992 CL HOUSTON, TX SP LUNAR, HOLOGIC, XITRON, EM SCAN, BICRON, CANBERRA, USDA ARS, CHILDRENS NUTR RES CTR, BAYLOR COLL MED C1 USA,ENVIRONM MED RES INST,DIV OCCUPAT PHYSIOL,NATICK,MA 01760. OI Friedl, Karl/0000-0002-3134-8427 NR 0 TC 3 Z9 3 U1 0 U2 0 PU PLENUM PRESS DIV PLENUM PUBLISHING CORP PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 SN 0090-5542 BN 0-306-44569-7 J9 BASIC LIFE SCI PY 1993 BP 99 EP 103 PG 5 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA BZ43M UT WOS:A1993BZ43M00023 PM 8110176 ER PT S AU HADUCH, TW AF HADUCH, TW BE Smith, MJ Salvendy, G TI OPERATOR INTERACTION WITH UNMANNED GROUND VEHICLES (UGV) (WITH LIMITED DATA-TRANSMISSION) SO HUMAN-COMPUTER INTERACTION, VOL 1: APPLICATIONS AND CASE STUDIES SE ADVANCES IN HUMAN FACTORS / ERGONOMICS LA English DT Proceedings Paper CT 5th International Conference on Human-Computer Interaction (HCI International 93) CY AUG 08-13, 1993 CL ORLANDO, FL SP AT&T, FUJI ELECT CO, JGC CORP, NEC CORP, PURDUE UNIV, UNIV CENT FLORIDA, UNIV WISCONSIN MADISON, ACM SIGCAPH, CHINESE ACAD SCI, CHINESE INST IND ENGINEERS, EEC, EUROPEAN STRATEG PROGRAMME RES & DEV INFORM TECHNOL, FINNISH INST OCCUPAT HLTH, HUMAN FACTORS SOC, IEEE, INST MANAGEMENT SERV, INST IND ENGINEERS, INTELLIGENT MFG SYST CTR, INT ERGON ASSOC, INT ROBOT & FACTORY AUTOMAT CTR, JAPAN ERGON RES SOC, JAPAN ASSOC MED INFORMAT, JAPAN INST OFF AUTOMAT, JAPAN MANAGEMENT ASSOC, JAPAN SOC HLTH SCI, NIOSH, NATL INST IND HLTH JAPAN, SOC INSTRUMENT & CONTROL ENGINEERS JAPAN, SOFTWARE PSYCHOL SOC, SWEDISH CROSS DISCIPLINARY SOC HUMAN COMP INTERACT RP HADUCH, TW (reprint author), USA,RES LAB,HUMAN RES & ENGN DIRECTORATE,ATTN AMSRL,HR,SC,ABERDEEN PROVING GROUND,MD 21005, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ELSEVIER SCIENCE PUBL B V PI AMSTERDAM PA SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0921-2647 BN 0-444-89540-X J9 ADV HUM FACT ERGON PY 1993 VL 19 BP 289 EP 294 PN A PG 6 WC Computer Science, Cybernetics; Ergonomics SC Computer Science; Engineering GA BA62K UT WOS:A1993BA62K00050 ER PT J AU POLLY, SM NELSON, W DINH, H THOMPSON, C MOORE, D BAKER, JR AF POLLY, SM NELSON, W DINH, H THOMPSON, C MOORE, D BAKER, JR TI ANTI-LEWIS ANTIBODY NEUTRALIZATION IN THE EVALUATION OF A HIGHLY SENSITIZED RENAL-TRANSPLANT CANDIDATE SO HUMAN IMMUNOLOGY LA English DT Meeting Abstract C1 WALTER REED ARMY MED CTR,ORGAN TRANSPLANT SERV,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 1 U2 1 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0198-8859 J9 HUM IMMUNOL JI Hum. Immunol. PY 1993 VL 37 SU 1 BP 119 EP 119 PG 1 WC Immunology SC Immunology GA LW989 UT WOS:A1993LW98900226 ER PT S AU KLAYMAN, DL AF KLAYMAN, DL BE Kinghorn, AD Balandrin, MF TI ARTEMISIA-ANNUA - FROM WEED TO RESPECTABLE ANTIMALARIAL PLANT SO HUMAN MEDICINAL AGENTS FROM PLANTS SE ACS SYMPOSIUM SERIES LA English DT Review CT SYMP ON HUMAN MEDICINAL AGENTS FROM PLANTS, AT THE 203RD NATIONAL MEETING OF THE AMERICAN CHEMICAL SOC CY APR 05-10, 1992 CL SAN FRANCISCO, CA SP AMER CHEM SOC, DIV AGR & FOOD CHEM, AMER SOC PHARMACOGNOSY, SOC ECON BOT, BRISTOL MYERS SQUIBB PHARM RES INST, GLAXO GRP RES, MURDOCK HEALTHCARE, PHYTOPHARM, SCHERING PLOUGH RES INST, SHAMAN PHARM, WYETH AYERST LABS RP KLAYMAN, DL (reprint author), WALTER REED ARMY INST RES,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307, USA. NR 0 TC 38 Z9 39 U1 1 U2 7 PU AMER CHEMICAL SOC PI WASHINGTON PA WASHINGTON SN 0097-6156 BN 0-8412-2705-5 J9 ACS SYM SER PY 1993 VL 534 BP 242 EP 255 PG 14 WC Plant Sciences; Pharmacology & Pharmacy SC Plant Sciences; Pharmacology & Pharmacy GA BY79A UT WOS:A1993BY79A00017 ER PT B AU ZHENG, JP CYGAN, PJ JOW, TR AF ZHENG, JP CYGAN, PJ JOW, TR GP IEEE TI ANOMALOUS METAL-POLYMER INTERFACE DEPENDENCE OF DIELECTRIC-BREAKDOWN IN POLYVINYLIDENE FLUORIDE SO IEEE 1993 ANNUAL REPORT: CONFERENCE ON ELECTRICAL INSULATION AND DIELECTRIC PHENOMENA LA English DT Proceedings Paper CT Conference on Electrical Insulation and Dielectric Phenomena (CEIDP) CY OCT 17-20, 1993 CL POCONO MANOR, PA SP IEEE, DIELECT & ELECT INSULAT SOC C1 ARMY RES LAB,ELECTR & POWER SOURCES DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-0966-9 PY 1993 BP 385 EP 389 PG 5 WC Engineering, Electrical & Electronic SC Engineering GA BA31X UT WOS:A1993BA31X00056 ER PT B AU ZHENG, JP CYGAN, PJ JOW, TR AF ZHENG, JP CYGAN, PJ JOW, TR GP IEEE TI ENHANCEMENT OF BREAKDOWN STRENGTH OF POLYETHERIMIDE LAMINATES SO IEEE 1993 ANNUAL REPORT: CONFERENCE ON ELECTRICAL INSULATION AND DIELECTRIC PHENOMENA LA English DT Proceedings Paper CT Conference on Electrical Insulation and Dielectric Phenomena (CEIDP) CY OCT 17-20, 1993 CL POCONO MANOR, PA SP IEEE, DIELECT & ELECT INSULAT SOC C1 ARMY RES LAB,ELECTR & POWER SOURCES DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-0966-9 PY 1993 BP 390 EP 395 PG 6 WC Engineering, Electrical & Electronic SC Engineering GA BA31X UT WOS:A1993BA31X00057 ER PT B AU CYGAN, PJ ZHENG, JP YEN, SPS JOW, TR AF CYGAN, PJ ZHENG, JP YEN, SPS JOW, TR GP IEEE TI THERMAL-TREATMENT OF POLYETHYLENE-2, 6-NAPHTHALATE (PEN) FILM AND ITS INFLUENCE ON THE MORPHOLOGY AND DIELECTRIC STRENGTH SO IEEE 1993 ANNUAL REPORT: CONFERENCE ON ELECTRICAL INSULATION AND DIELECTRIC PHENOMENA LA English DT Proceedings Paper CT Conference on Electrical Insulation and Dielectric Phenomena (CEIDP) CY OCT 17-20, 1993 CL POCONO MANOR, PA SP IEEE, DIELECT & ELECT INSULAT SOC C1 ARMY RES LAB,ELECTR & POWER SOURCES DIRECTORATE,FT MONMOUTH,NJ 07703. NR 0 TC 2 Z9 2 U1 0 U2 3 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-0966-9 PY 1993 BP 630 EP 635 PG 6 WC Engineering, Electrical & Electronic SC Engineering GA BA31X UT WOS:A1993BA31X00096 ER PT S AU KOSINSKI, JA BALLATO, A LU, YC AF KOSINSKI, JA BALLATO, A LU, YC BE Levy, M McAvoy, BR TI EFFECTS OF NONUNIFORM DISTRIBUTION OF MOTION ON DETERMINATIONS OF PIEZOELECTRIC COUPLING AND CONSTANTS USING IEEE 176-1987 SO IEEE 1993 ULTRASONICS SYMPOSIUM PROCEEDINGS, VOLS 1 AND 2 SE ULTRASONICS SYMPOSIUM LA English DT Proceedings Paper CT IEEE 1993 Ultrasonics Symposium CY OCT 31-NOV 03, 1993 CL BALTIMORE, MD SP ULTRASON FERROELECT & FREQUENCY CONTROL SOC C1 USA,RES LAB,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 SN 1051-0117 BN 0-7803-1278-3 J9 ULTRASON PY 1993 BP 537 EP 540 PG 4 WC Acoustics; Engineering, Electrical & Electronic SC Acoustics; Engineering GA BA31N UT WOS:A1993BA31N00100 ER PT J AU THEDREZ, BJ SADDOW, SE LIU, YQ WOOD, C WILSON, R LEE, CH AF THEDREZ, BJ SADDOW, SE LIU, YQ WOOD, C WILSON, R LEE, CH TI EXPERIMENTAL AND THEORETICAL INVESTIGATION OF LARGE OUTPUT POWER Q-SWITCHED ALGAAS SEMICONDUCTOR-LASERS SO IEEE PHOTONICS TECHNOLOGY LETTERS LA English DT Article ID QUANTUM-WELL LASERS; LOSS MODULATOR AB The response of AlGaAs two-section broad-area lasers to picosecond optical excitations was investigated. Q-switched pulses of up to 6 W amplitude with pulse widths less than 30 ps were measured. Asymmetric Q-switched behavior was theoretically predicted and excellent agreement with experimental results achieved on time scales shorter than the cavity round-trip time. C1 LAB PHYS SCI,COLL PK,MD 20742. USA,RES LAB,ADELPHI,MD 20783. RP THEDREZ, BJ (reprint author), UNIV MARYLAND,DEPT ELECT ENGN,JOINT PROGRAM ADV ELECTR MAT,COLL PK,MD 20742, USA. NR 12 TC 9 Z9 9 U1 0 U2 0 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 1041-1135 J9 IEEE PHOTONIC TECH L JI IEEE Photonics Technol. Lett. PD JAN PY 1993 VL 5 IS 1 BP 19 EP 22 DI 10.1109/68.185047 PG 4 WC Engineering, Electrical & Electronic; Optics; Physics, Applied SC Engineering; Optics; Physics GA KJ706 UT WOS:A1993KJ70600007 ER PT B AU TIDROW, SC WILBER, WD TIDROW, MZ AF TIDROW, SC WILBER, WD TIDROW, MZ BE VanDuzer, T TI LASER-ABLATION OF YBCO - UTILIZING O-18 TO INVESTIGATE THE INCORPORATION OF OXYGEN INTO THE LASER PLUME SO IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY, VOL 3, NO 1, MARCH 1993 PTS 2-4 LA English DT Proceedings Paper CT 1992 Applied Superconductivity Conference CY AUG 23-28, 1992 CL CHICAGO, IL SP IEEE, ARGONNE NATL LAB, BABCOCK & WILCOX, US DOE, DIV BASIC ENERGY SCI CONSERVAT & RENEWABLE, US DOE, HIGH ENERGY PHYS, DEFENSE ADV RES PROJECTS AGCY, FERMI NATL ACCELERAT LAB, LAWRENCE BERKELEY LAB, TELEDYNE WAH CHANG C1 USA,ELECTR & POWER SOURCES DIRECTORATE,RES LAB,AMSRL EP EC H,FT MONMOUTH,NJ 07703. RI Tidrow, Steven/C-8133-2013 NR 0 TC 0 Z9 0 U1 0 U2 3 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 PY 1993 BP 1078 EP 1081 PG 4 WC Engineering, Electrical & Electronic; Physics, Applied; Physics, Condensed Matter SC Engineering; Physics GA BZ49H UT WOS:A1993BZ49H00237 ER PT J AU HOLLAND, MM EGGERS, PD GUINTO, S STEVENSON, RD COLOMBO, G AF HOLLAND, MM EGGERS, PD GUINTO, S STEVENSON, RD COLOMBO, G TI ADVANCED RAILGUN EXPERIMENTAL TEST-RESULTS AND IMPLICATIONS FOR THE FUTURE SO IEEE TRANSACTIONS ON MAGNETICS LA English DT Article; Proceedings Paper CT 6TH SYMP ON ELECTROMAGNETIC LAUNCHER TECHNOLOGY CY 1992 CL UNIV TEXAS AUSTIN, INST ADV TECHNOL, AUSTIN, TX HO UNIV TEXAS AUSTIN, INST ADV TECHNOL AB An advanced railgun has been designed, fabricated and tested for the Army. The railgun barrel is 7m long and has a 90mm (inner diameter) round bore. The barrel design incorporates unique features intended to contribute to improved railgun performance compared to more conventional designs. These features include very high bore stiffness and high bore pre-stress. These combined features minimize bore deflections and relative motion of bore mating parts, thus preventing plasma armature leakage and blow-by and enhancing performance. The high bore stiffness and prestress design features are gained through the application of advanced materials and engineering solutions. In particular, the use of high modulus insulator materials, high strength to weight graphite/epoxy structures and a high pressure (20,000 psi) hydraulic annulus allow for improved performance while also permitting a substantial reduction (50-80%) in size and weight over more conventional approaches. Experimental test results and comparison with predicted results are presented. Additionally, recommendations for further potential design improvements that would lead to additional reductions (50-65%) in size and weight and enhanced performance are presented and discussed. C1 USA,CTR ARMAMENT RES DEV & ENGN,PICATINNY ARSENAL,NJ. RP HOLLAND, MM (reprint author), SPARTA SYST INC,SAN DIEGO,CA 92121, USA. NR 6 TC 2 Z9 2 U1 1 U2 1 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9464 J9 IEEE T MAGN JI IEEE Trans. Magn. PD JAN PY 1993 VL 29 IS 1 BP 419 EP 424 DI 10.1109/20.195611 PN 2 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA KN287 UT WOS:A1993KN28700018 ER PT J AU SINK, DA CHANG, DI DAVIS, A COLOMBO, G HILDENBRAND, DJ AF SINK, DA CHANG, DI DAVIS, A COLOMBO, G HILDENBRAND, DJ TI THE ANALYSIS AND MODELING OF THE ARDEC 2.5 KM/S 20-MM PLASMA RAILGUN SHOT SO IEEE TRANSACTIONS ON MAGNETICS LA English DT Article; Proceedings Paper CT 6TH SYMP ON ELECTROMAGNETIC LAUNCHER TECHNOLOGY CY 1992 CL UNIV TEXAS AUSTIN, INST ADV TECHNOL, AUSTIN, TX HO UNIV TEXAS AUSTIN, INST ADV TECHNOL ID ELECTROMAGNETIC LAUNCHER; ARMATURES AB The 20-mm round-bore plasma railgun was successfully fired at the ARDEC electric gun facility. The 4-m gun with copper rails and alumina composite insulators was operated using a light-gas gun injector to start the projectile, already located in the gun, moving prior to the introduction of current. Current from the EMACK homopolar generator (HPG) was commutated into the gun by an explosively-actuated opening switch. The muzzle velocity was recorded by breakwires and flash x-rays at 2.5 km/s. B-dot sensors, rail current Rogowski coils, and breech and muzzle voltage measurements provided data on the in-bore dynamics of the armature. Post-shot analysis using the ARMRAIL (ARMature Physics and RAILgun Performance Model) code successfully provided calculations reproducing all the main features of the data. Models account for the observed secondary arcs present throughout the shot and the basis for the code and physics modeling is given. C1 USA,CTR ARMAMENT RES DEV & ENGN,DIV ELECT ARMAMENTS,PICATINNY ARSENAL,NJ 07801. PARKER KINET DESIGNS INC,WHARTON,NJ 07885. RP SINK, DA (reprint author), SCI APPLICAT INT CORP,98 FORD RD,SUITE D,DENVILLE,NJ 07834, USA. NR 20 TC 0 Z9 0 U1 0 U2 0 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9464 J9 IEEE T MAGN JI IEEE Trans. Magn. PD JAN PY 1993 VL 29 IS 1 BP 511 EP 516 DI 10.1109/20.195628 PN 2 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA KN287 UT WOS:A1993KN28700035 ER PT J AU KAPLAN, Z SAPHIER, D MELNIK, D GORELIC, Z ASHKENAZY, J SUDAI, M KIMHE, D MELNIK, M SMITH, S JUHASZ, A AF KAPLAN, Z SAPHIER, D MELNIK, D GORELIC, Z ASHKENAZY, J SUDAI, M KIMHE, D MELNIK, M SMITH, S JUHASZ, A TI ELECTROTHERMAL AUGMENTATION OF A SOLID-PROPELLANT LAUNCHER SO IEEE TRANSACTIONS ON MAGNETICS LA English DT Article; Proceedings Paper CT 6TH SYMP ON ELECTROMAGNETIC LAUNCHER TECHNOLOGY CY 1992 CL UNIV TEXAS AUSTIN, INST ADV TECHNOL, AUSTIN, TX HO UNIV TEXAS AUSTIN, INST ADV TECHNOL AB The augmentation of a ballistic process, based on the well known solid propellant burning by an electrothermal (ET) energy source, is the subject of an experimental and theoretical investigation to obtain improved launching techniques. The plasma jet formation method, the internal ballistics modeling approach and the experimental test bed are described. Experimental results are disclosed showing the enhanced burning rate of a solid propellant ignited and augmented by the injection of plasma jets. We also present preliminary experimental evidence of improved performance of the new proposed method over that of conventional ballistics using solid propellant alone. C1 USA,STRATEG DEF COMMAND,HUNTSVILLE,AL 35807. USA,BALLIST RES LAB,ABERDEEN PROVING GROUND,MD 21005. RP KAPLAN, Z (reprint author), SOREQ NUCL RES CTR,PROPULS PHYS LAB,IL-70600 YAVNE,ISRAEL. NR 9 TC 12 Z9 12 U1 0 U2 0 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9464 J9 IEEE T MAGN JI IEEE Trans. Magn. PD JAN PY 1993 VL 29 IS 1 BP 573 EP 578 DI 10.1109/20.195639 PN 2 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA KN287 UT WOS:A1993KN28700046 ER PT J AU POWELL, JD ZIELINSKI, AE AF POWELL, JD ZIELINSKI, AE TI CAPILLARY DISCHARGE IN THE ELECTROTHERMAL GUN SO IEEE TRANSACTIONS ON MAGNETICS LA English DT Article; Proceedings Paper CT 6TH SYMP ON ELECTROMAGNETIC LAUNCHER TECHNOLOGY CY 1992 CL UNIV TEXAS AUSTIN, INST ADV TECHNOL, AUSTIN, TX HO UNIV TEXAS AUSTIN, INST ADV TECHNOL ID NONIDEAL PLASMAS; ARCS; LAUNCHERS AB A one-dimensional model is described for calculating the properties of plasma arcs in ablating, cylindrical capillaries. The basic assumptions and governing equations are presented and the results of some numerical solutions are discussed. These results are also compared with experimental measurements of the voltage across the arc, as well the pressure measured at a specific point in the capillary tube. The degree to which theory and experiment agree is discussed in some detail and possible reasons for the lack of agreement, where it exists, are pointed out. RP POWELL, JD (reprint author), USA,BALLIST RES LAB,ABERDEEN PROVING GROUND,MD 21005, USA. NR 16 TC 51 Z9 58 U1 0 U2 5 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9464 J9 IEEE T MAGN JI IEEE Trans. Magn. PD JAN PY 1993 VL 29 IS 1 BP 591 EP 596 DI 10.1109/20.195642 PN 2 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA KN287 UT WOS:A1993KN28700049 ER PT J AU WREN, GP OBERLE, WF SINHA, N HOSANGADI, A DASH, SM AF WREN, GP OBERLE, WF SINHA, N HOSANGADI, A DASH, SM TI US ARMY ACTIVITIES IN MULTIDIMENSIONAL MODELING OF ELECTROTHERMAL-CHEMICAL GUNS SO IEEE TRANSACTIONS ON MAGNETICS LA English DT Article; Proceedings Paper CT 6TH SYMP ON ELECTROMAGNETIC LAUNCHER TECHNOLOGY CY 1992 CL UNIV TEXAS AUSTIN, INST ADV TECHNOL, AUSTIN, TX HO UNIV TEXAS AUSTIN, INST ADV TECHNOL AB Progress towards developing a first-principles capability to simulate the dominant physical processes in an electrothermal-chemical (ETC) gun is described. The computational model is the CRAFT Navier-Stokes solver which implements advanced implicit/upwind numerics with strongly coupled chemistry and generalized grid dynamics. The model provides a framework for incorporation of physics submodules developed by a team of Science Applications International Corporation (SAIC), Sandia National Laboratories (SNL), and the U.S. Army Ballistic Research Laboratory (BRL) scientists as well as industry and university researchers. RP WREN, GP (reprint author), USA,BALLIST RES LAB,WASHINGTON,DC 20310, USA. NR 8 TC 9 Z9 9 U1 0 U2 0 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9464 J9 IEEE T MAGN JI IEEE Trans. Magn. PD JAN PY 1993 VL 29 IS 1 BP 631 EP 636 DI 10.1109/20.195649 PN 2 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA KN287 UT WOS:A1993KN28700056 ER PT J AU BATTEH, JH POWELL, JD ROLADER, GE AF BATTEH, JH POWELL, JD ROLADER, GE TI EFFECT OF A TRANSIENT CURRENT PROFILE ON THE DYNAMICS OF RAILGUN ARCS SO IEEE TRANSACTIONS ON MAGNETICS LA English DT Article; Proceedings Paper CT 6TH SYMP ON ELECTROMAGNETIC LAUNCHER TECHNOLOGY CY 1992 CL UNIV TEXAS AUSTIN, INST ADV TECHNOL, AUSTIN, TX HO UNIV TEXAS AUSTIN, INST ADV TECHNOL ID PLASMA ARMATURES; INTERCHANGE INSTABILITY; DRIVEN AB A one- dimensional, time-dependent model for describing transient behavior in railgun plasma armatures is employed in order to investigate the effects produced by a time-varying current profile. Ablation from the rail surfaces is also accounted for. The governing equations are solved numerically to produce as a function of time and space the electrodynamic and thermodynamic properties of the arc. These quantities are shown to be considerably different from those predicted by commonly used quasi-static models. The importance of these transient effects and how they can affect the design of projectiles and the analysis of diagnostic data are discussed. C1 USA,BALLIST RES LAB,ABERDEEN PROVING GROUND,MD 21005. SCI APPLICAT INT CORP,SHALIMAR,FL 32579. RP BATTEH, JH (reprint author), SCI APPLICAT INT CORP,MARIETTA,GA 30062, USA. NR 14 TC 3 Z9 3 U1 0 U2 2 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9464 J9 IEEE T MAGN JI IEEE Trans. Magn. PD JAN PY 1993 VL 29 IS 1 BP 739 EP 744 DI 10.1109/20.195668 PN 2 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA KN287 UT WOS:A1993KN28700075 ER PT J AU CHU, SH AF CHU, SH TI BALLOTING MOTION OF SLEKE LAUNCH PACKAGES IN EM RAILGUNS SO IEEE TRANSACTIONS ON MAGNETICS LA English DT Article; Proceedings Paper CT 6TH SYMP ON ELECTROMAGNETIC LAUNCHER TECHNOLOGY CY 1992 CL UNIV TEXAS AUSTIN, INST ADV TECHNOL, AUSTIN, TX HO UNIV TEXAS AUSTIN, INST ADV TECHNOL AB This paper reports some balloting motion computational results of the SLEKE (Sabot Launched Electric-gun Kinetic Energy) launch packages, which are in their early stage of development. The computation model considers the effects of the EM (Lorentz) propulsion force, friction, air resistance, gravity, elastic forces, and clearance between the launch package and the barrel. The axial, normal and yaw displacement, velocity and acceleration; friction; deformations and forces at the interfacing points are computed. The results of this study indicate that the balloting force for SLEKE launch packages is on the order of the air drag force and that a uniformly distributed power source would be more desirable than sharp pulse current for electromagnetic railguns. RP CHU, SH (reprint author), USA,ARMAMENT RES,CTR DEV & ENGN,DIV ELECT ARMAMENTS,BLDG 329,PICATINNY ARSENAL,NJ 07806, USA. NR 2 TC 1 Z9 1 U1 0 U2 0 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9464 J9 IEEE T MAGN JI IEEE Trans. Magn. PD JAN PY 1993 VL 29 IS 1 BP 769 EP 774 DI 10.1109/20.195673 PN 2 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA KN287 UT WOS:A1993KN28700080 ER PT J AU COLON, N TRAN, L LUU, K PAUL, L CHANG, DI SINK, DA AF COLON, N TRAN, L LUU, K PAUL, L CHANG, DI SINK, DA TI HIGH TRANSITION VELOCITIES FOR SOLID ARMATURES IN THE 10-MM MTR RAILGUN SO IEEE TRANSACTIONS ON MAGNETICS LA English DT Article; Proceedings Paper CT 6TH SYMP ON ELECTROMAGNETIC LAUNCHER TECHNOLOGY CY 1992 CL UNIV TEXAS AUSTIN, INST ADV TECHNOL, AUSTIN, TX HO UNIV TEXAS AUSTIN, INST ADV TECHNOL ID DESIGN AB The transitioning of a solid armature on the Materials Test Railgun (MTR) at ARDEC (Armament Research, Development and Engineering Center) was studied and data on high-velocity transitions analyzed. The railgun has a 10-mm square-bore, is 0.6-m long, and designed with a bolted construction for experimental flexibility. Solid aluminum, 7075-series alloy armatures were accelerated to 1.75 km/s and were observed to transition at approximately 1.3 km/s. These 3-g armatures were designed in a U-shaped configuration. The railgun was driven by a stored energy of 200 kJ from the ARDEC 10-kV capacitor bank power supply. The test configuration, armature design, and shot data are provided. The muzzle voltage data was analyzed using model equations for the transitioning of the solid armature to a hybrid armature with arcing contacts. The model is used to obtain the temperature at the armature contacts and the resultant railgun muzzle voltage which is compared to the measured voltage. The data clearly shows the development of the voltage as a continuous process involving the various phases for the contacts and the model reflects this behavior. For transitioning times of approximately 600 mus there is an initial period with low voltages (less-than-or-equal-to 20 V) followed by a sharp rise to almost-equal-to 60 V. After that point there is a smooth rise to almost-equal-to 200 V and a quickly increasing voltage to 800 V after 600 mus. An analysis based on a model for the contacts provides an understanding of the contact physics during the transitioning process up to 200 V. C1 SCI APPLICAT INT CORP,DENVILLE,NJ 07834. RP COLON, N (reprint author), USA,ARMAMENT RES,CTR DEV & ENGN,DIV ELECT ARMAMENTS,PICANTINNY ARSENAL,NJ 07801, USA. NR 6 TC 8 Z9 8 U1 0 U2 0 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9464 J9 IEEE T MAGN JI IEEE Trans. Magn. PD JAN PY 1993 VL 29 IS 1 BP 775 EP 780 DI 10.1109/20.195674 PN 2 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA KN287 UT WOS:A1993KN28700081 ER PT J AU ZIELINSKI, AE AF ZIELINSKI, AE TI A PROJECTILE-ORIENTED, DESIGN STUDY FOR A CANNON-CALIBER ELECTROMAGNETIC LAUNCHER SO IEEE TRANSACTIONS ON MAGNETICS LA English DT Article; Proceedings Paper CT 6TH SYMP ON ELECTROMAGNETIC LAUNCHER TECHNOLOGY CY 1992 CL UNIV TEXAS AUSTIN, INST ADV TECHNOL, AUSTIN, TX HO UNIV TEXAS AUSTIN, INST ADV TECHNOL AB In the design of an efficient gun system the terminal performance must be considered in conjunction with the required input energy. Power conversion for electromagnetic acceleration can involve an arduous assessment of numerous, complex components. This paper presents a summary of the results for integrating a finned-rod with a solid armature. An initial design is presented for a rod-projectile launched from a 23 mm, round-bore augmented railgun. We evaluate the projectile design by considering launch, flight, and terminal effects. Four capacitor-based pulsed power supply systems are considered for the launcher. The host vehicle weight limit and largest number of projectiles stowed provide guidance in selecting the optimum configuration. The study utilizes a wide array of parameters for estimating system weight. Simple scaling for power components is provided to further appraise launcher feasibility. Projectile effectiveness is evaluated at the target using a weapons simulation code and a similar caliber conventionally launched projectile. RP ZIELINSKI, AE (reprint author), USA,BALLIST RES LAB,ABERDEEN PROVING GROUND,MD 21005, USA. NR 12 TC 1 Z9 1 U1 0 U2 0 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9464 J9 IEEE T MAGN JI IEEE Trans. Magn. PD JAN PY 1993 VL 29 IS 1 BP 889 EP 894 DI 10.1109/20.195694 PN 2 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA KN287 UT WOS:A1993KN28700101 ER PT J AU CHANG, DI LONG, B CHIU, D KING, R HERSHKOWITZ, J AF CHANG, DI LONG, B CHIU, D KING, R HERSHKOWITZ, J TI A PULSE FORMING NETWORK AND TEST FIXTURE FOR SCREENING ELECTROTHERMAL CHEMICAL CANDIDATE PROPELLANTS SO IEEE TRANSACTIONS ON MAGNETICS LA English DT Article; Proceedings Paper CT 6TH SYMP ON ELECTROMAGNETIC LAUNCHER TECHNOLOGY CY 1992 CL UNIV TEXAS AUSTIN, INST ADV TECHNOL, AUSTIN, TX HO UNIV TEXAS AUSTIN, INST ADV TECHNOL AB A pulse power supply has been designed to support the development and evaluation of candidate propellants for an Electrothermal Chemical (ETC) gun program at ARDEC. The flexibility needed for this evaluation is achieved through the modular design of the test fixture and power supply. The test fixture is comprised of a plasma chamber and instrumented combustion chamber interconnected by a convergent-divergent nozzle. The combustion chamber is terminated by an exhaust nozzle and overall thrust is measured. The volume of both chambers and nozzle configurations can be varied to optimize performance. A 10 mm gun tube is an option. The power supply is readily reconfigured to provide either an RLC or PFN discharge. Either configuration can store up to 34 kJ and provide a pulse between 0.5 to 2 ms. Load behavior and the effects of parasitic energy losses on circuit performance are presented. The results will be compared with PSpice circuit models. A presentation of the experimental pulse power system and resulting data will be provided. C1 PARKER KINET DESIGN,WHARTON,NJ 07885. USA,CTR RES DEV & ENGN,DIV ENERGET & WARHEADS,PICATINNY ARSENAL,NJ 07806. GEO CTR,LAKE HOPATCONG,NJ. RP CHANG, DI (reprint author), USA,CTR RES DEV & ENGN,DIV ELECT ARMAMENT,PICATINNY ARSENAL,NJ 07806, USA. NR 4 TC 1 Z9 2 U1 0 U2 0 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9464 J9 IEEE T MAGN JI IEEE Trans. Magn. PD JAN PY 1993 VL 29 IS 1 BP 919 EP 922 DI 10.1109/20.195700 PN 2 PG 4 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA KN287 UT WOS:A1993KN28700107 ER PT J AU CORADESCHI, T COLOMBO, G DAVIS, A PUTERBAUGH, R BERNHARDT, T DOBBIE, C GAYWOOD, P HARRIS, E MCNAB, I AF CORADESCHI, T COLOMBO, G DAVIS, A PUTERBAUGH, R BERNHARDT, T DOBBIE, C GAYWOOD, P HARRIS, E MCNAB, I TI 52 MEGAJOULE ELECTRIC GUN TEST FACILITY SO IEEE TRANSACTIONS ON MAGNETICS LA English DT Article; Proceedings Paper CT 6TH SYMP ON ELECTROMAGNETIC LAUNCHER TECHNOLOGY CY 1992 CL UNIV TEXAS AUSTIN, INST ADV TECHNOL, AUSTIN, TX HO UNIV TEXAS AUSTIN, INST ADV TECHNOL AB The Electric Armaments Division at the US Army Armament Research, Development and Engineering Center has constructed an advanced, high energy, electric gun test facility at its Building 717 site, on the grounds of Picatinny Arsenal in northern New Jersey. A 52 megajoule, capacitor-based, pulsed power supply, consisting of sixteen individual 3.25 megajoule modules, has been installed. Pulse forming networks have been designed to provide appropriate pulses for both ET and EM railgun loads. A 120 mm ET launch fixture has been installed and a 90 mm EM railgun is to be installed in summer 1992. A 900 square foot control and data acquisition center is installed in Building 717A. The layout of the facility, design of the pulse power supply and configuration of the diagnostic systems will be discussed. C1 MAXWELL LABS INC,BALBOA DIV,SAN DIEGO,CA 92123. RP CORADESCHI, T (reprint author), USA,CTR ARMAMENT RES DEV & ENGN,DIV ELECT ARMAMENTS,BLDG 329,PICATINNY ARSENAL,NJ 07806, USA. NR 0 TC 3 Z9 4 U1 0 U2 1 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9464 J9 IEEE T MAGN JI IEEE Trans. Magn. PD JAN PY 1993 VL 29 IS 1 BP 923 EP 928 DI 10.1109/20.195701 PN 2 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA KN287 UT WOS:A1993KN28700108 ER PT J AU DETHLEFSEN, R MCNAB, I DOBBIE, C BERNHARDT, T PUTERBAUGH, R LEVINE, F CORADESCHI, T RINALDI, V AF DETHLEFSEN, R MCNAB, I DOBBIE, C BERNHARDT, T PUTERBAUGH, R LEVINE, F CORADESCHI, T RINALDI, V TI PULSE POWER APPLICATIONS OF SILICON DIODES IN EML CAPACITIVE PULSERS SO IEEE TRANSACTIONS ON MAGNETICS LA English DT Article; Proceedings Paper CT 6TH SYMP ON ELECTROMAGNETIC LAUNCHER TECHNOLOGY CY 1992 CL UNIV TEXAS AUSTIN, INST ADV TECHNOL, AUSTIN, TX HO UNIV TEXAS AUSTIN, INST ADV TECHNOL AB Crowbar diodes are used for increasing the energy transfer from capacitive pulse forming networks. They also prevent voltage reversal on the energy storage capacitors. 52 mm diameter diodes with a 5 kV reverse blocking voltage, rated 40 kA were successfully used for the 32 MJ SSG rail gun. An uprated diode with increased current capability and a 15 kV reverse blocking voltage has been developed. Transient thermal analysis has predicted the current ratings for different pulse length. Analysis verification is obtained from destructive testing. C1 USA,CTR ARMAMENT RES DEV & ENGN,PICATINNY,NJ 07806. INT RECTIFIER CANADA LTD,MARKHAM L3R 3L1,ON,CANADA. RP DETHLEFSEN, R (reprint author), MAXWELL LABS INC,SAN DIEGO,CA 92123, USA. NR 1 TC 3 Z9 5 U1 0 U2 2 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9464 J9 IEEE T MAGN JI IEEE Trans. Magn. PD JAN PY 1993 VL 29 IS 1 BP 934 EP 938 DI 10.1109/20.195703 PN 2 PG 5 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA KN287 UT WOS:A1993KN28700110 ER PT J AU SARJEANT, WJ GOODELL, BD LANGLIE, SL PAN, KC AF SARJEANT, WJ GOODELL, BD LANGLIE, SL PAN, KC TI TECHNICAL TRADEOFFS FOR DOWNSIZING ETC POWER-SYSTEMS SO IEEE TRANSACTIONS ON MAGNETICS LA English DT Article; Proceedings Paper CT 6TH SYMP ON ELECTROMAGNETIC LAUNCHER TECHNOLOGY CY 1992 CL UNIV TEXAS AUSTIN, INST ADV TECHNOL, AUSTIN, TX HO UNIV TEXAS AUSTIN, INST ADV TECHNOL AB Technical tradeoffs for downsizing three different ETC power system concepts are presented with mid-term goals established for system size and weight reductions. The desired features of an ETC tank advanced technology demonstrator are selected to baseline the system projections. The key impeding technologies and issues that are important to make significant system size and weight reductions are identified. The likelihood of achieving the mid-term goals is discussed. C1 FMC CORP,DIV NAVAL SYST,4800 E RIVER RD,MINNEAPOLIS,MN 55421. USA,CTR ARMAMENT RES DEV & ENGN,PICATINNY ARSENAL,NJ 07806. RP SARJEANT, WJ (reprint author), SUNY BUFFALO,312 BONNER ECE,BUFFALO,NY 14260, USA. NR 14 TC 6 Z9 6 U1 0 U2 0 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9464 J9 IEEE T MAGN JI IEEE Trans. Magn. PD JAN PY 1993 VL 29 IS 1 BP 1054 EP 1059 DI 10.1109/20.195726 PN 2 PG 6 WC Engineering, Electrical & Electronic; Physics, Applied SC Engineering; Physics GA KN287 UT WOS:A1993KN28700133 ER PT J AU KOSCICA, TE AF KOSCICA, TE TI MICROSTRIP QUARTER-WAVE HIGH-VOLTAGE DC BLOCK SO IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES LA English DT Note ID BIAS AB A microstrip high voltage de block is presented. Silicon rubber is used to insulate a quarter-wave coupler and the resulting effective dielectric constant and impedance are discussed. DC isolation up to 4500 V is achieved. RP KOSCICA, TE (reprint author), USA,MP,SLCET,FT MONMOUTH,NJ 07703, USA. NR 12 TC 0 Z9 0 U1 0 U2 0 PU IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2394 SN 0018-9480 J9 IEEE T MICROW THEORY JI IEEE Trans. Microw. Theory Tech. PD JAN PY 1993 VL 41 IS 1 BP 162 EP 164 DI 10.1109/22.210248 PG 3 WC Engineering, Electrical & Electronic SC Engineering GA KX644 UT WOS:A1993KX64400027 ER PT J AU NGUYEN, BQ AF NGUYEN, BQ TI WORK TIME MEASUREMENT SYSTEM (WTMS) - THE FRONT-END TOOL FOR REDESIGNING THE WORK PROCESS SO IFIP TRANSACTIONS A-COMPUTER SCIENCE AND TECHNOLOGY LA English DT Article AB Trying to understand the current work process in detail was the prelude to change for improvement. Since April 1990, AIRMICS has been using an internally developed work-time measurement system (WTMS Tool) to increase efficiency and to utilize the work force more effectively. Efficiency was realized by using more advanced computing technologies to improve or to automate certain work activities. Effective utilization was achieved by tracking and ensuring that the work force was spending time doing the correct tasks in the correct priority. The WTMS Tool described in this paper is an automated system successfully implemented at AIRMICS for providing the management with critical information on how work time is distributed among assigned tasks and what activities are associated in doing a specific task. Work-time data are collected from the work force by using a windows-based computer application. Data are statistically calculated at non-working hours, and the results are electronically mailed to management and interested members during the night on a monthly basis. Organizational cooperation and leadership were the two critical factors that led to successful implementation of the WTMS Tool at AIRMICS. Cooperation was secured because measured data were not used for evaluating the quality of work or setting performance standards. Another factor was that management used the information to improve the organization, its people's skills, and the work process. RP NGUYEN, BQ (reprint author), GEORGIA INST TECHNOL,USA,RES LAB,SOFTWARE TECHNOL BRANCH,115 OKEEFE BLDG,ATLANTA,GA 30332, USA. NR 14 TC 0 Z9 0 U1 0 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0926-5473 J9 IFIP TRANS A JI IFIP Trans. A-Comp. Sci. Technol. PY 1993 VL 26 BP 111 EP 119 PG 9 WC Computer Science, Information Systems; Computer Science, Theory & Methods SC Computer Science GA LJ989 UT WOS:A1993LJ98900009 ER PT J AU CHANH, TC ROMANOWSKI, MJ HEWETSON, JF AF CHANH, TC ROMANOWSKI, MJ HEWETSON, JF TI MONOCLONAL-ANTIBODY PROPHYLAXIS AGAINST THE INVIVO TOXICITY OF RICIN IN MICE SO IMMUNOLOGICAL INVESTIGATIONS LA English DT Article ID A CHAIN; PURIFICATION; PROTECTION; COMMUNIS; TOXINS; CELLS AB A BALB/c murine IgG1 monoclonal antibody, designated BG11-G2, specific for ricin was generated. BG11-G2 antibody did not bind to either purified ricin chain A or chain B, but recognized an antigenic determinant whose conformation requires the combination of the two chains in the formation of the native ricin molecule. It did not react with the protein synthesis inhibitor, T-2 mycotoxin, or with the sodium channel blockers, saxitoxin and tetrodotoxin. As little as 0.78 mug/ml of BG11-G2 IgG1 anti-ricin monoclonal antibody completely protected against the in vitro toxicity of ricin as determined by [H-3]leucine uptake in EL-4 cell assays. Passive intraperitoneal infusion of purified BG11-G2 antibody into BALB/c mice one day prior to a lethal challenge with ricin considerably delayed the onset of toxicity and death. Better protection was obtained with BG11-G2 infused before and after ricin challenge. C1 USA,INST INFECT DIS,DEPT PATHOPHYSIOL,FREDERICK,MD 20071. RP CHANH, TC (reprint author), SW FDN BIOMED RES,DEPT VIROL & IMMUNOL,SAN ANTONIO,TX 78228, USA. NR 17 TC 22 Z9 24 U1 0 U2 1 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0882-0139 J9 IMMUNOL INVEST JI Immunol. Invest. PY 1993 VL 22 IS 1 BP 63 EP 72 DI 10.3109/08820139309066194 PG 10 WC Immunology SC Immunology GA KK622 UT WOS:A1993KK62200006 PM 8440524 ER PT J AU FRIEDLANDER, AM BHATNAGAR, R LEPPLA, SH JOHNSON, L SINGH, Y AF FRIEDLANDER, AM BHATNAGAR, R LEPPLA, SH JOHNSON, L SINGH, Y TI CHARACTERIZATION OF MACROPHAGE SENSITIVITY AND RESISTANCE TO ANTHRAX LETHAL TOXIN SO INFECTION AND IMMUNITY LA English DT Article ID HAMSTER OVARY CELLS; DENSITY-LIPOPROTEIN RECEPTOR; EPIDERMAL GROWTH-FACTOR; PSEUDOMONAS EXOTOXIN-A; CYTOPLASMIC DOMAIN; DIPHTHERIA-TOXIN; BACILLUS-ANTHRACIS; PROTECTIVE ANTIGEN; ADENYLATE-CYCLASE; LOW-PH AB Anthrax lethal toxin, which consists of two proteins, protective antigen and lethal factor, is cytolytic for macrophages. Macrophages from different mouse strains were found to vary in their sensitivities to toxin. C3H mouse macrophages lysed by lethal factor concentrations of 0.001 mug/ml were 100,000 times more sensitive than those from resistant A/J mice. We analyzed various stages of the intoxication process to determine the basis for this resistance. Direct binding studies with radioiodinated protective antigen revealed that the affinity (K(d), approximately 0.5 nM) and number of receptors per cell (25,000 to 33,000) were the same in sensitive and resistant cells. Proteolytic activation of protective antigen by a cell surface protease and subsequent binding of lethal factor were also the same in both sensitive and resistant macrophages. Resistant A/J macrophages were not cross-resistant to other toxins and a virus which, like lethal toxin, require vesicular acidification for activity, implying that resistance is not due to a defect in vesicular acidification. When introduced into the cytosol by osmotic lysis of pinosomes, lethal factor in the absence of protective antigen was cytolytic for the sensitive macrophages while resistant cells were unaffected. Thus, lethal factor by itself possesses the toxic activity of lethal toxin. These results suggest that macrophage resistance is due to a defect at a stage occurring after toxin internalization. A/J macrophages may lack the putative lethal factor target in the cytosol or be defective in the further processing or activation of lethal factor in the cytosol or in endocytic vesicles. RP FRIEDLANDER, AM (reprint author), USA,MED RES INST INFECT DIS,FREDERICK,MD 21702, USA. NR 60 TC 111 Z9 114 U1 0 U2 1 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0019-9567 J9 INFECT IMMUN JI Infect. Immun. PD JAN PY 1993 VL 61 IS 1 BP 245 EP 252 PG 8 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA KF636 UT WOS:A1993KF63600032 PM 8380282 ER PT B AU GERHART, GR MEITZLER, T SOHN, EJ CHOE, H AF GERHART, GR MEITZLER, T SOHN, EJ CHOE, H BE Holst, GC TI THE EVALUATION OF DELTA-T USING STATISTICAL CHARACTERISTICS OF THE TARGET AND BACKGROUND SO INFRARED IMAGING SYSTEMS: DESIGN, ANALYSIS, MODELING, AND TESTING IV SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Infrared Imaging System: Design, Analysis, Modeling, and Testing IV CY APR 14-15, 1993 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,TARDEC,AMSTA RSA,WARREN,MI 48397. RI Meitzler, Thomas/D-1065-2017 NR 0 TC 2 Z9 2 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1205-8 J9 P SOC PHOTO-OPT INS PY 1993 VL 1969 BP 11 EP 20 DI 10.1117/12.154736 PG 10 WC Optics SC Optics GA BZ45J UT WOS:A1993BZ45J00002 ER PT B AU SCOTT, L AF SCOTT, L BE Holst, GC TI MODELING STARING THERMAL-SYSTEMS WITH FLIR92 SO INFRARED IMAGING SYSTEMS: DESIGN, ANALYSIS, MODELING, AND TESTING IV SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Infrared Imaging System: Design, Analysis, Modeling, and Testing IV CY APR 14-15, 1993 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,NIGHT VIS & ELECTR SENSORS DIRECTORATE,FT BELVOIR,VA 22060. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1205-8 J9 P SOC PHOTO-OPT INS PY 1993 VL 1969 BP 21 EP 26 DI 10.1117/12.154721 PG 6 WC Optics SC Optics GA BZ45J UT WOS:A1993BZ45J00003 ER PT B AU WATKINS, WR AF WATKINS, WR BE Holst, GC TI ENVIRONMENTAL BUGS INVADE EO IMAGING-SYSTEMS SO INFRARED IMAGING SYSTEMS: DESIGN, ANALYSIS, MODELING, AND TESTING IV SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Infrared Imaging System: Design, Analysis, Modeling, and Testing IV CY APR 14-15, 1993 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,RES LAB,BATTLEFIELD ENVIRONM DIRECTORATE,WHITE SANDS MISSILE RANGE,NM 88002. NR 0 TC 1 Z9 1 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1205-8 J9 P SOC PHOTO-OPT INS PY 1993 VL 1969 BP 42 EP 53 DI 10.1117/12.154737 PG 12 WC Optics SC Optics GA BZ45J UT WOS:A1993BZ45J00005 ER PT B AU BELL, PA HOOVER, CW PRUCHNIC, SJ AF BELL, PA HOOVER, CW PRUCHNIC, SJ BE Holst, GC TI STANDARD NETD TEST PROCEDURE FOR FLIR SYSTEMS WITH VIDEO OUTPUTS SO INFRARED IMAGING SYSTEMS: DESIGN, ANALYSIS, MODELING, AND TESTING IV SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Infrared Imaging System: Design, Analysis, Modeling, and Testing IV CY APR 14-15, 1993 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,NIGHT VIS & ELECTR SENSORS DIRECTORATE,FT BELVOIR,VA 22060. NR 0 TC 7 Z9 7 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1205-8 J9 P SOC PHOTO-OPT INS PY 1993 VL 1969 BP 194 EP 205 DI 10.1117/12.154715 PG 12 WC Optics SC Optics GA BZ45J UT WOS:A1993BZ45J00019 ER PT B AU FLETCHER, J BARNES, H PINCZEWSKI, G AF FLETCHER, J BARNES, H PINCZEWSKI, G BE Holst, GC TI HARDWARE-IN-THE-LOOP AND FIELD TESTING OF THE TRIBAND IMAGING INFRARED RADIOMETER SO INFRARED IMAGING SYSTEMS: DESIGN, ANALYSIS, MODELING, AND TESTING IV SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Infrared Imaging System: Design, Analysis, Modeling, and Testing IV CY APR 14-15, 1993 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,PROGRAM EXECUT OFF,SFAE GPL TMD SS-P,HUNTSVILLE,AL 35807. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1205-8 J9 P SOC PHOTO-OPT INS PY 1993 VL 1969 BP 285 EP 295 DI 10.1117/12.154722 PG 11 WC Optics SC Optics GA BZ45J UT WOS:A1993BZ45J00026 ER PT J AU CREASIA, DA THURMAN, JD AF CREASIA, DA THURMAN, JD TI COMPARATIVE ACUTE INHALATION TOXICITY OF A SALINE SUSPENSION AND AN ETHANOL SOLUTION OF T-2 MYCOTOXIN IN MICE SO INHALATION TOXICOLOGY LA English DT Article AB We compared retention, distribution, toxicity, and histopathological change in mice after exposure to aerosols of T-2 suspended in saline or dissolved in ethanol. We found that the LC50 for mice exposed for 10 min to an aerosol of a saline suspension of T-2 was 0.035 +/- 0.02 mg T-2 per liter air, which was lower than the LC50 (0.380 +/-0.08 mg T-2 per liter air) for an aerosol of T-2 dissolved in ethanol. However, within about 15 min postexposure, most of the T-2 deposited in the respiratory tract was translocated from the respiratory tract regardless of whether the T-2 aerosol was from a saline suspension or ethanol solution. Also, although T-2 is an inflammatory agent to dermis and gastrointestinal epithelium, T-2 from either aerosol did not produce any histological evidence of inflammation in the respiratory tract. C1 NATL CTR TOXICOL RES,PATHOL ASSOCIATES INC,JEFFERSON,AR 72079. USA,MED RES INST INFECT DIS,DIV TOXICOL,FREDERICK,MD 21701. NR 12 TC 3 Z9 3 U1 0 U2 0 PU TAYLOR & FRANCIS PI BRISTOL PA 1900 FROST ROAD, SUITE 101, BRISTOL, PA 19007-1598 SN 0895-8378 J9 INHAL TOXICOL JI Inhal. Toxicol. PD JAN-MAR PY 1993 VL 5 IS 1 BP 33 EP 41 DI 10.3109/08958379309034492 PG 9 WC Toxicology SC Toxicology GA KQ828 UT WOS:A1993KQ82800002 ER PT B AU WILES, G SIM, L AF WILES, G SIM, L GP INST NAVIGAT TI MONTE-CARLO ANALYSIS FOR GPS PERFORMANCE ON AN ARTILLERY PROJECTILE SO INSTITUTE OF NAVIGATION PROCEEDINGS OF THE 49TH ANNUAL MEETING: FUTURE GLOBAL NAVIGATION AND GUIDANCE LA English DT Proceedings Paper CT 49th Annual Meeting of the Institute-of-Navigation on Future Global Navigation and Guidance CY JUN 21-23, 1993 CL CAMBRIDGE, MA SP INST NAVIGAT, CHARLES STARK DRAPER LAB C1 USA,RES LAB,NEW CARROLLTON,MD. NR 0 TC 0 Z9 0 U1 0 U2 1 PU INST NAVIGATION PI WASHINGTON PA 815 15TH ST NW, STE 832, WASHINGTON, DC 20005 PY 1993 BP 365 EP 368 PG 4 WC Engineering, Aerospace; Transportation SC Engineering; Transportation GA BA50A UT WOS:A1993BA50A00038 ER PT J AU PARK, OC HOPKINS, R AF PARK, OC HOPKINS, R TI INSTRUCTIONAL CONDITIONS FOR USING DYNAMIC VISUAL-DISPLAYS - A REVIEW SO INSTRUCTIONAL SCIENCE LA English DT Article ID ANIMATION; GRAPHICS; MEDIA; PHYSICS; LESSON; MOTION AB A review of research related to the learning effect of dynamic versus static visual displays in media-based instruction is presented. The analysis reveals that the dynamic visual display (DVD) is generally more effective than the static visual display (SVD). However, the research findings do not consistently support the superior effect of DVDs. These conflicting findings seem to be related to the different theoretical rationales and methodological approaches used in various studies and suggest that the use of DVDs should be determined selectively. From the literature review and theoretical discussions about instructional functions of DVDs, we propose six instructional conditions under which DVDs can be effectively used. The conditions are for: (a) demonstrating sequential actions in a procedural task; (b) simulating causal models of complex system behaviors; (c) explicitly representing invisible system functions and behaviors; (d) illustrating a task which is difficult to describe verbally; (e) providing a visual analogy for an abstract and symbolic concept, and (f) obtaining attention focused on specific tasks or presentation displays. Finally, several important considerations for the design and presentation of DVDs are discussed. RP PARK, OC (reprint author), USA,RES INST,5001 EISENHOWER AVE,ALEXANDRIA,VA 22333, USA. NR 82 TC 56 Z9 56 U1 3 U2 7 PU KLUWER ACADEMIC PUBL PI DORDRECHT PA SPUIBOULEVARD 50, PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS SN 0020-4277 J9 INSTR SCI JI Instr. Sci. PY 1993 VL 21 IS 6 BP 427 EP 449 DI 10.1007/BF00118557 PG 23 WC Education & Educational Research; Psychology, Educational SC Education & Educational Research; Psychology GA LP217 UT WOS:A1993LP21700001 ER PT B AU ABRAHAM, DD FREEMAN, GE HALL, BR PRATT, TC AF ABRAHAM, DD FREEMAN, GE HALL, BR PRATT, TC BE Mitchell, JK TI DATA COLLECTION IN WETLAND ENVIRONMENTS SO INTEGRATED RESOURCE MANAGEMENT & LANDSCAPE MODIFICATION FOR ENVIRONMENTAL PROTECTION SE ASAE PUBLICATION LA English DT Proceedings Paper CT International Symposium on Integrated Resource Management and Landscape Modification for Environmental Protection CY DEC 13-14, 1993 CL CHICAGO, IL SP AMER SOC AGR ENGINEERS, AMER AGR ECON ASSOC, AMER SOC AGRON & CROP SCI, EQUIPMENT MANUFACTURERS INST, COUNCIL AGR SCI & TECHNOL, TENNESSEE VALLEY AUTHORITY, SOIL & WATER CONSERVAT SOC, AMER SOC CIVIL ENGINEERS, USDA, ARS, AMER SOC LANDSCAPE ARCHITECTS, NATL ASSOC CONSERVAT DIST, AMER WATER RESOURCES ASSOC, USDA, ECON RES SERV DE ULTRASONIC; WATER SURFACE ELEVATIONS; DISTANCE METERS; DATA COLLECTION C1 USA CORPS ENGINEERS,WATERWAYS EXPT STN,HYDRAUL LAB,VICKSBURG,MS. NR 0 TC 0 Z9 0 U1 0 U2 1 PU AMER SOC AGRICULTURAL ENGINEERS PI ST JOSEPH PA 2950 NILES RD, ST JOSEPH, MI 49085-9659 BN 0-929355-43-1 J9 ASAE PUBL PY 1993 VL 93 IS 13 BP 99 EP 102 PG 4 WC Engineering, Environmental; Water Resources SC Engineering; Water Resources GA BC59L UT WOS:A1993BC59L00013 ER PT B AU FREEMAN, GE HALL, BR ABRAHAM, DD AF FREEMAN, GE HALL, BR ABRAHAM, DD BE Mitchell, JK TI FLOW RESISTANCE AND SEDIMENT RETENTION FOR BULRUSHES IN WETLAND ENVIRONMENTS SO INTEGRATED RESOURCE MANAGEMENT & LANDSCAPE MODIFICATION FOR ENVIRONMENTAL PROTECTION SE ASAE PUBLICATION LA English DT Proceedings Paper CT International Symposium on Integrated Resource Management and Landscape Modification for Environmental Protection CY DEC 13-14, 1993 CL CHICAGO, IL SP AMER SOC AGR ENGINEERS, AMER AGR ECON ASSOC, AMER SOC AGRON & CROP SCI, EQUIPMENT MANUFACTURERS INST, COUNCIL AGR SCI & TECHNOL, TENNESSEE VALLEY AUTHORITY, SOIL & WATER CONSERVAT SOC, AMER SOC CIVIL ENGINEERS, USDA, ARS, AMER SOC LANDSCAPE ARCHITECTS, NATL ASSOC CONSERVAT DIST, AMER WATER RESOURCES ASSOC, USDA, ECON RES SERV DE OPEN CHANNEL FLOW; SEDIMENT; LOW RESISTANCE; BULRUSHES; HYDRAULIC ROUGHNESS C1 USA,WATERWAYS EXPT STN,HYDRAUL LAB,VICKSBURG,MS 39180. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC AGRICULTURAL ENGINEERS PI ST JOSEPH PA 2950 NILES RD, ST JOSEPH, MI 49085-9659 BN 0-929355-43-1 J9 ASAE PUBL PY 1993 VL 93 IS 13 BP 276 EP 285 PG 10 WC Engineering, Environmental; Water Resources SC Engineering; Water Resources GA BC59L UT WOS:A1993BC59L00036 ER PT B AU JOHNSON, BE RAPHELT, NK AF JOHNSON, BE RAPHELT, NK BE Mitchell, JK TI DESIGNING RISER PIPES WITH GIS SO INTEGRATED RESOURCE MANAGEMENT & LANDSCAPE MODIFICATION FOR ENVIRONMENTAL PROTECTION SE ASAE PUBLICATION LA English DT Proceedings Paper CT International Symposium on Integrated Resource Management and Landscape Modification for Environmental Protection CY DEC 13-14, 1993 CL CHICAGO, IL SP AMER SOC AGR ENGINEERS, AMER AGR ECON ASSOC, AMER SOC AGRON & CROP SCI, EQUIPMENT MANUFACTURERS INST, COUNCIL AGR SCI & TECHNOL, TENNESSEE VALLEY AUTHORITY, SOIL & WATER CONSERVAT SOC, AMER SOC CIVIL ENGINEERS, USDA, ARS, AMER SOC LANDSCAPE ARCHITECTS, NATL ASSOC CONSERVAT DIST, AMER WATER RESOURCES ASSOC, USDA, ECON RES SERV C1 WATERWAYS EXPT STN COE,VICKSBURG,MS. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC AGRICULTURAL ENGINEERS PI ST JOSEPH PA 2950 NILES RD, ST JOSEPH, MI 49085-9659 BN 0-929355-43-1 J9 ASAE PUBL PY 1993 VL 93 IS 13 BP 326 EP 329 PG 4 WC Engineering, Environmental; Water Resources SC Engineering; Water Resources GA BC59L UT WOS:A1993BC59L00042 ER PT J AU AGNEW, JW AF AGNEW, JW GP SOC APPL LEARNING TECHNOL TI CONDUCTING ANATOMY AND PHYSIOLOGY LABORATORY SESSIONS IN A DISTANCE LEARNING CURRICULUM SO INTERACTIVE MULTIMEDIA 93: PROCEEDINGS LA English DT Proceedings Paper CT Interactive Multimedia 93 CY AUG 25-27, 1993 CL WASHINGTON, DC SP SOC APPL LEARNING TECHNOL C1 USA,DIV MED & SURG,ANAT & PHYSIOL BRANCH,FT SAM HOUSTON,TX 78234. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC APPLIED LEARNING TECHNOLOGY PI WARRENTON PA 50 CULPEPER ST, WARRENTON, VA 22186 PY 1993 BP 113 EP 114 PG 2 WC Computer Science, Interdisciplinary Applications; Education & Educational Research SC Computer Science; Education & Educational Research GA BA39X UT WOS:A1993BA39X00030 ER PT B AU NOWAK, GA DECUSATIS, CM LITYNSKI, DM DAS, PK AF NOWAK, GA DECUSATIS, CM LITYNSKI, DM DAS, PK BE Gulyaev, YV Pape, DR TI INTEGRATED OPTICAL MULTICHANNEL ACOUSTO-ELECTRO-OPTIC DEVICE SO INTERNATIONAL CONFERENCE ON OPTICAL INFORMATION PROCESSING SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT 1st International Conference on Optical Information Processing CY AUG 02-07, 1993 CL RUSSIAN ACAD SCI HOUSE, ST PETERSBURG, RUSSIA SP RUSSIAN ACAD SCI, A F IOFFE PHYS TECH INST, AT&T ST PETERSBURG, CO LTD RESPONSIBIL STACK, RUSSIA, ENGN & CONSTRUCT CORP CREATION, RUSSIA, FINANCIAL & PROD CO ESTRA, RUSSIA, IEEE, LASERS & ELECTRO OPT SOC, US, RUSSIAN ACAD SCI, INST RADIO ENGN & ELECTR, MINIST SCI, HIGHER SCH EDUC & TECH POLICY RUSSIA, MOSCOW SCI PROD CORP ASTRA, OPT SOC AMER, RADAR MMS LENINETZ, SPIE, RUSSIA CHAPTER, SOC PHOTO OPT INSTRUMENTAT ENGINEERS, ST PETERSBURG INNOVAT BANK, ST PETERSBURG STATE ACAD AEROSP INSTRUMENTAT HO RUSSIAN ACAD SCI HOUSE C1 US MIL ACAD,PHOTON RES CTR,W POINT,NY 10996. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1310-0 J9 P SOC PHOTO-OPT INS PY 1993 VL 2051 BP 116 EP 123 PG 8 WC Acoustics; Computer Science, Information Systems; Optics SC Acoustics; Computer Science; Optics GA BZ74E UT WOS:A1993BZ74E00014 ER PT J AU ENGHARDT, MH VALENTE, PT DAY, DH AF ENGHARDT, MH VALENTE, PT DAY, DH TI PAPILLOMA OF BARTHOLIN GLAND DUCT CYST - 1ST REPORT OF A CASE SO INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY LA English DT Note DE BARTHOLINS GLAND CYST; BARTHOLINS GLAND TUMOR; VULVA AB A 50-year-old woman underwent excision of a vaginal cyst. Its distal end lay in the submucosal tissue of the posterior lateral aspect of the vulvar vestibule near the orifice of Bartholin's gland. The caudal wall of the cyst contained a papilloma with an epithelial lining which consisted of columnar and stratified polygonal cells resembling squamous and transitional epithelium. The histochemical attributes of the papillary epithelium were homologous to those of Bartholin's gland. Immunohistochemical studies supported glandular and squamous differentiation. Evolution from a dysontogenetic remnant of Mullerian origin cannot be excluded with certainty, but location and histopathology were consistent with origin from Bartholin's gland duct. The presence of mucin and the absence of a smooth muscle investment exclude derivation from Gartner's duct. Cysts of Bartholin's gland are common, but solid benign tumors are rare. We have been unable to find a report of a papilloma of either vulva or vagina with features similar to those in our patient. C1 UNIV TEXAS, HLTH SCI CTR, DEPT PATHOL, SAN ANTONIO, TX 78284 USA. UNIV TEXAS, HLTH SCI CTR, DEPT OBSTET & GYNECOL, SAN ANTONIO, TX 78284 USA. NATL NAVAL MED CTR, BETHESDA, MD 20814 USA. UNIFORMED SERV UNIV HLTH SCI, DEPT OBSTET & GYNECOL, BETHESDA, MD 20814 USA. RP ENGHARDT, MH (reprint author), BROOKE ARMY MED CTR, DEPT PATHOL, FT SAM HOUSTON, TX 78234 USA. NR 37 TC 3 Z9 3 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0277-1691 J9 INT J GYNECOL PATHOL JI Int. J. Gynecol. Pathol. PD JAN PY 1993 VL 12 IS 1 BP 86 EP 92 DI 10.1097/00004347-199301000-00012 PG 7 WC Obstetrics & Gynecology; Pathology SC Obstetrics & Gynecology; Pathology GA KD246 UT WOS:A1993KD24600012 PM 8418083 ER PT J AU GRACE, FI AF GRACE, FI TI NONSTEADY PENETRATION OF LONG RODS INTO SEMIINFINITE TARGETS SO INTERNATIONAL JOURNAL OF IMPACT ENGINEERING LA English DT Article ID MODELS AB This paper describes a new one-dimensional theory of nonsteady penetration of long rods into semi-infinite targets. The target is viewed as a ''finite mass'' that resides within the semi-infinite target space. Thus, an equation of motion for the target was constructed so that together with erosion and penetrator deceleration equations, expressions for penetration rates and depths were obtained. Forces acting on the target and penetrator are defined in terms of only ordinary strength levels usually associated with dynamic properties or work-hardened material states. Also, the concept of critical impact velocity was used to establish the onset of penetration in this formulation. This penetration equation corresponds in exact form to hydrodynamic theory in the limits of small strengths and/or high impact velocity. Results for penetration rates agree well with hydrocode calculations, and predicted penetrations agree with experimental data over an impact velocity range of 0-5,000 m/s. RP GRACE, FI (reprint author), USA, RES LAB, ABERDEEN PROVING GROUND, MD 21005 USA. NR 22 TC 10 Z9 12 U1 0 U2 1 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND SN 0734-743X EI 1879-3509 J9 INT J IMPACT ENG JI Int. J. Impact Eng. PY 1993 VL 14 IS 1-4 BP 303 EP 314 DI 10.1016/0734-743X(93)90029-7 PG 12 WC Engineering, Mechanical; Mechanics SC Engineering; Mechanics GA LX893 UT WOS:A1993LX89300028 ER PT J AU SCHMIDT, EM HELD, BJ SAVICK, DS AF SCHMIDT, EM HELD, BJ SAVICK, DS TI HYPERVELOCITY LAUNCH DYNAMICS SO INTERNATIONAL JOURNAL OF IMPACT ENGINEERING LA English DT Article; Proceedings Paper CT 1992 HYPERVELOCITY IMPACT SYMP CY NOV 17-19, 1992 CL AUSTIN, TX AB The launch dynamics from a generic hypervelocity cannon are considered over the velocity range from 1500 through 3500 m/s. Both fin and flare stabilized projectiles are examined for the influence of in-bore dynamics, muzzle blast, sabot discard, and free flight aerodynamics upon their trajectory. Computations are performed using codes developed and validated for conventional cannon with ordnance muzzle velocities (approximately 1700 m/s). While the extension into the hypervelocity regime is not supported by experimental data, this initial study is intended to aid in defining potential problem areas. RP SCHMIDT, EM (reprint author), USA,RES LAB,WEAPONS TECHNOL DIRECTORATE,ABERDEEN PROVING GROUND,MD 21005, USA. NR 8 TC 0 Z9 0 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0734-743X J9 INT J IMPACT ENG JI Int. J. Impact Eng. PY 1993 VL 14 IS 1-4 BP 619 EP 630 DI 10.1016/0734-743X(93)90057-E PG 12 WC Engineering, Mechanical; Mechanics SC Engineering; Mechanics GA LX893 UT WOS:A1993LX89300056 ER PT J AU KING, JW AF KING, JW TI THE INVERSE MOLECULAR TRANSFORM INDEX - A DESCRIPTOR FOR MOLECULAR SIMILARITY ANALYSIS SO INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY LA English DT Article; Proceedings Paper CT International Symposium / 33rd Annual Sanibel Symposium on the Application of Fundamental Theory to Problems of Biology and Pharmacology CY MAR 13-20, 1993 CL ST AUGUSTINE, FL SP UNIV FLORIDA, FAC & STAFF QUANTUM THEORY PROJECT, USA, ARMY RES OFF, USN, OFF NAVAL RES, US EPA, US DOE, DIGITAL EQUIPMENT CORP, IBM, KENDALL SQUARE AB The fast Fourier transform of a free-induction decay curve generated by a Fourier operation on a bond distance matrix representation of a molecule gives a frequency domain spectrum that, when plotted as a line of points, is similar to a chromatogram and is called the inverse molecular transform. Within a series of compounds including lower alkanes, alkenes, cyclics, heteroalipathics, and aromatics, the amplitude of the transform ordinates increased directly with the size of the molecule and with going from straight chain to cyclic structures with the same number of carbon atoms. A derived transform index gave a unitary numerical structure descriptor that was used in a topological comparison of structures and is called the transform similarity ratio. With further investigation, this methodology appears to have the potential to generate correlation descriptors, other molecular similarity measures, or an index of protein globularity. (C) 1993 John Wiley & Sons, Inc. RP KING, JW (reprint author), USA,EDGEWOOD RES,CTR DEV & ENGN,ABERDEEN PROVING GROUND,MD 21010, USA. NR 18 TC 1 Z9 1 U1 0 U2 0 PU JOHN WILEY & SONS INC PI NEW YORK PA 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0020-7608 J9 INT J QUANTUM CHEM JI Int. J. Quantum Chem. PY 1993 SU 20 BP 139 EP 145 PG 7 WC Chemistry, Physical; Mathematics, Interdisciplinary Applications; Physics, Atomic, Molecular & Chemical SC Chemistry; Mathematics; Physics GA ML585 UT WOS:A1993ML58500014 ER PT J AU COHEN, JM FAMINI, GR AF COHEN, JM FAMINI, GR TI AN IMPROVED EIKONAL TREATMENT OF ROTATIONALLY INELASTIC HE--H-2 SCATTERING SO INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY LA English DT Article; Proceedings Paper CT International Symposium / 33rd Annual Sanibel Symposium on Atomic, Molecular, and Condensed Matter Theory and Computational Methods CY MAR 13-20, 1993 CL PONCE DE LEON CONF CTR, ST AUGUSTINE, FL SP UNIV FLORIDA, QUANTUM THEORY PROJECT HO PONCE DE LEON CONF CTR ID APPROXIMATION; TRANSITIONS; COLLISIONS; EXCITATION AB A variation of the usual semiclassical short wavelength (eikonal) method was recently applied to model calculations of electronically diabatic atom-atom collisions. Microreversibility was computationally imposed on the dynamics by following trajectories initiating in the ground and excited states simultaneously. When improved transition probabilities for several two-state systems were obtained in this manner, a multistate application was selected. Self-consistent eikonal/averaged effective potential (SCE/ABP) state to state calculations are performed for rotationally inelastic HeH2 scattering at total energies of .1 and .9 eV. using an (8,2) basis (7 states). Phase shifted amplitudes are introduced that add constraints to the coupled differential equations and reduce cpu time. Definite parity partial and total cross sections compare favorably to the previous semiclassical coupled states (SCS) results of Billing (1978) as well as to both the quantum ADP j(z) and CC results of Shimoni and Kouri (1977). (C) 1993 John Wiley and Sons, Inc. RP COHEN, JM (reprint author), USA,CHEM & BIOL DEF AGCY,SMCCR-RSP-C,ABERDEEN PROVING GROUND,MD 21010, USA. NR 21 TC 0 Z9 0 U1 0 U2 0 PU JOHN WILEY & SONS INC PI NEW YORK PA 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0020-7608 J9 INT J QUANTUM CHEM JI Int. J. Quantum Chem. PY 1993 SU 27 BP 527 EP 545 PG 19 WC Chemistry, Physical; Mathematics, Interdisciplinary Applications; Physics, Atomic, Molecular & Chemical SC Chemistry; Mathematics; Physics GA ML586 UT WOS:A1993ML58600048 ER PT J AU MIELKE, SL TAWA, GJ TRUHLAR, DG SCHWENKE, DW AF MIELKE, SL TAWA, GJ TRUHLAR, DG SCHWENKE, DW TI PARTIAL WIDTHS OF FESHBACH FUNNEL RESONANCES IN THE NA(3P)CENTER-DOT-H-2 EXCIPLEX SO INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY LA English DT Article; Proceedings Paper CT International Symposium / 33rd Annual Sanibel Symposium on Atomic, Molecular, and Condensed Matter Theory and Computational Methods CY MAR 13-20, 1993 CL PONCE DE LEON CONF CTR, ST AUGUSTINE, FL SP UNIV FLORIDA, QUANTUM THEORY PROJECT HO PONCE DE LEON CONF CTR ID POTENTIAL-ENERGY SURFACES; DIABATIC REPRESENTATION; CONICAL INTERSECTIONS; COLLISIONS; SPECTROSCOPY; H-2; NAH AB We have located five zero angular momentum resonance states in the funnel associated with the lowest conical intersection of the Na(3p).H-2 exciplex, and we have characterized the four narrowest of these in terms of total and partial widths. The resonant contributions of the metastable states to state-to-state energy transfer greatly exceed the background contributions. (C) 1993 John Wiley and Sons, Inc. C1 UNIV MINNESOTA, ARMY HIGH PERFORMANCE COMP RES CTR, MINNEAPOLIS, MN 55455 USA. NASA, AMES RES CTR, MOFFETT FIELD, CA 94035 USA. RP MIELKE, SL (reprint author), UNIV MINNESOTA, INST SUPERCOMP, DEPT CHEM, CHEM PHYS PROGRAM, MINNEAPOLIS, MN 55455 USA. RI Mielke, Steven/B-7533-2008; schwenke, david/I-3564-2013; Truhlar, Donald/G-7076-2015 OI Mielke, Steven/0000-0002-1938-7503; Truhlar, Donald/0000-0002-7742-7294 NR 43 TC 9 Z9 9 U1 0 U2 1 PU JOHN WILEY & SONS INC PI NEW YORK PA 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0020-7608 J9 INT J QUANTUM CHEM JI Int. J. Quantum Chem. PY 1993 SU 27 BP 621 EP 632 PG 12 WC Chemistry, Physical; Mathematics, Interdisciplinary Applications; Physics, Atomic, Molecular & Chemical SC Chemistry; Mathematics; Physics GA ML586 UT WOS:A1993ML58600054 ER PT J AU MACHAN, TR AF MACHAN, TR TI INDIVIDUAL RIGHTS, THE COMMON GOOD AND THE ENVIRONMENT SO INTERNATIONAL JOURNAL OF SOCIAL ECONOMICS LA English DT Article DE COMMUNITY RELATIONS; ENVIRONMENT; INDIVIDUAL BEHAVIOR AB Disputes the view of the communitarians, a recently emerged group of political theorists that individualism, especially the theory of natural individual rights, stands as an obstacle to desirable community life for human beings. Argues that the only objection of individualism to communitarianism rests on the communitarian endorsement of coercion and violation of individual rights; in point of fact, individualism, with a proper understanding of human nature, supports community life that is voluntarily chosen; such communities have greater solidarity than those established by coercion. Uses the topic of environmentalism, which might offer strong support for coercive communitarianism, to illustrate how an individualist analysis gives strong support to the values of community life; indeed, stronger support than communitarianism because individual rights are very powerful legal trumps on such environmentally destructive acts as dumping, rationing, and otherwise merely blunting the injuries of pollution. RP MACHAN, TR (reprint author), US MIL ACAD,W POINT,NY 10996, USA. NR 10 TC 1 Z9 1 U1 2 U2 4 PU MCB UNIV PRESS LTD PI BRADFORD PA 60/62 TOLLER LANE, BRADFORD, W YORKSHIRE, ENGLAND BD8 9BY SN 0306-8293 J9 INT J SOC ECON PY 1993 VL 20 IS 9 BP 54 EP 65 DI 10.1108/03068299310044371 PG 12 WC Economics SC Business & Economics GA MM690 UT WOS:A1993MM69000005 ER PT J AU JENKINS, TR TANGEN, C MACDONALD, JS WEISS, G CHAPMAN, R HANTEL, A AF JENKINS, TR TANGEN, C MACDONALD, JS WEISS, G CHAPMAN, R HANTEL, A TI A PHASE-II TRIAL OF PIROXANTRONE IN ADENOCARCINOMA OF THE PANCREAS - A SOUTHWEST-ONCOLOGY-GROUP STUDY SO INVESTIGATIONAL NEW DRUGS LA English DT Note DE PIROXANTRONE; ADENOCARCINOMA OF THE PANCREAS ID AGENTS AB Thirty-five evaluable patients with advanced adenocarcinoma of the pancreas were treated with piroxantrone at a dose of 150 mg/m(2) intravenously every 21 days. No objective responses were observed (95% confidence interval 0%-10%). Toxicities of grade greater than or equal to 3 were primarily hematologic and were seen in 28 patients. Piroxantrone is inactive in pancreatic cancer and no further investigation of this agent in this tumor is recommended. C1 BROOKE ARMY MED CTR,SAN ANTONIO,TX. SW ONCOL GRP,CTR STAT,SEATTLE,WA. TEMPLE UNIV,PHILADELPHIA,PA. UNIV TEXAS,HLTH SCI CTR,SAN ANTONIO,TX. HENRY FORD HOSP,DETROIT,MI. LOYOLA UNIV,STRITCH SCH MED,MAYWOOD,IL. FU NCI NIH HHS [CA-04915, CA-22433, CA-37429] NR 7 TC 7 Z9 7 U1 0 U2 0 PU KLUWER ACADEMIC PUBL PI DORDRECHT PA SPUIBOULEVARD 50, PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS SN 0167-6997 J9 INVEST NEW DRUG JI Invest. New Drugs PY 1993 VL 11 IS 4 BP 329 EP 331 DI 10.1007/BF00874432 PG 3 WC Oncology; Pharmacology & Pharmacy SC Oncology; Pharmacology & Pharmacy GA MR907 UT WOS:A1993MR90700010 PM 8157474 ER PT J AU BERENBERG, JL TANGEN, C MACDONALD, JS BARLOGIE, B LAUFMAN, LR AF BERENBERG, JL TANGEN, C MACDONALD, JS BARLOGIE, B LAUFMAN, LR TI VM-26 IN GASTRIC-CANCER - A SOUTHWEST-ONCOLOGY-GROUP STUDY SO INVESTIGATIONAL NEW DRUGS LA English DT Note DE TENIPOSIDE; GASTRIC CANCER ID ETOPOSIDE AB The Southwest Oncology Group conducted a trial of VM-26 (teniposide) in patients with advanced gastric cancer. VM-26 60 mg/m(2) IV infusion over 30-45 minutes was given daily for 5 days every 21 days. Twenty-one eligible patients with measurable disease and a SWOG performance status of 0-2 were analyzed for response and toxicity. Partial responses were seen in 2 of the 21 eligible patients (9.5%). Median survival was 3.8 months. Severe or life-threatening toxicity was observed in 13/21 (62%) patients. This included two drug related deaths related to neutropenic sepsis and seven other patients with grade 4 granulocytopenia (<500/mm(3)). Liver dysfunction and hypotension were seen less often and were not dose limiting. Although the modest activity seen was comparable to that of VP-16 (etoposide) as a single agent, the hematologic toxicity observed in this trial would likely preclude further trials of VM-26 (teniposide) in advanced gastric cancer. C1 CANC RES CTR HAWAII,HONOLULU,HI. TRIPLER ARMY MED CTR,HONOLULU,HI 96859. SW ONCOL GRP,CTR STAT,SEATTLE,WA. TEMPLE UNIV,PHILADELPHIA,PA. UNIV ARKANSAS MED SCI HOSP,LITTLE ROCK,AR. COLUMBUS CCOP,COLUMBUS,OH. FU NCI NIH HHS [CA-37429, CA-37981, CA-37234] NR 5 TC 1 Z9 1 U1 0 U2 1 PU KLUWER ACADEMIC PUBL PI DORDRECHT PA SPUIBOULEVARD 50, PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS SN 0167-6997 J9 INVEST NEW DRUG JI Invest. New Drugs PY 1993 VL 11 IS 4 BP 333 EP 334 DI 10.1007/BF00874433 PG 2 WC Oncology; Pharmacology & Pharmacy SC Oncology; Pharmacology & Pharmacy GA MR907 UT WOS:A1993MR90700011 PM 8157475 ER PT J AU CHABOT, KA BRESCIA, JA AF CHABOT, KA BRESCIA, JA TI EVALUATION OF PRIMERS FOR ADHESIVELY-BONDED AIRCRAFT REPAIR SO JOURNAL OF ADHESION SCIENCE AND TECHNOLOGY LA English DT Article DE ADHESIVE; PRIMERS; SILANE; ALUMINUM; ALODINE; ADHESIVELY BONDED JOINTS AB This paper contains the results of an investigation to determine the effectiveness of primers in promoting adhesion and improving the environmental durability of epoxy adhesive bonds on grit-blasted aluminum substrates. The control for this study consisted of phosphoric acid anodization of substrates followed by the application of EC 3924 B primer. The following primers were evaluated on grit-blasted substrates: (1) EC 3924 B; (2) Metlbond 6726; (3) Dow Corning Z-6040; and (4) EA9203. In addition, grit blasting followed by Alodine application was compared with the other primers. Studies include shear strength evaluations of each primer/adhesive system at 23 and 105-degrees-C. In order to assess the relative durability of each system, shear strength testing at 93-degrees-C of samples exposed for 2 weeks to a 93-degrees-C/condensing humidity environment and wedge crack extension testing of samples exposed for a 2-week period to a 60-degrees-C/condensing humidity environment were performed. The peel strengths of the systems were determined by conducting floating roller peel studies at -55, 23, and 105-degrees-C. Statistical analysis of the data revealed that the level of performance provided by EC 3924 B, solvent-borne, corrosion inhibiting control primer on phosphoric acid-anodized surfaces exceeded that of all the primers on grit-blasted substrates. However, when comparing the primers applied after only a grit-blast treatment, gamma-glycidoxy-propyltrimethoxysilane primer showed statistically better results than the other primer systems. RP CHABOT, KA (reprint author), USA,ARMAMENT RES DEV & ENGN CTR,SMCAR AET M,BLDG 183,PICATINNY ARSENAL,NJ 07806, USA. NR 12 TC 2 Z9 2 U1 1 U2 2 PU VSP BV PI ZEIST PA PO BOX 346, 3700 AH ZEIST, NETHERLANDS SN 0169-4243 J9 J ADHES SCI TECHNOL JI J. Adhes. Sci. Technol. PY 1993 VL 7 IS 11 BP 1183 EP 1194 DI 10.1163/156856193X00042 PG 12 WC Engineering, Chemical; Materials Science, Multidisciplinary; Mechanics SC Engineering; Materials Science; Mechanics GA MJ206 UT WOS:A1993MJ20600004 ER PT J AU VENKATARAMAN, SK NELSON, JC HSIEH, AJ KOHLSTEDT, DL GERBERICH, WW AF VENKATARAMAN, SK NELSON, JC HSIEH, AJ KOHLSTEDT, DL GERBERICH, WW TI CONTINUOUS MICROSCRATCH MEASUREMENTS OF THIN-FILM ADHESION STRENGTHS SO JOURNAL OF ADHESION SCIENCE AND TECHNOLOGY LA English DT Article DE ADHESION; THIN FIRMS; MICROSCRATCH; TOUGHNESS ID WEAR-RESISTANT COATINGS; MECHANICAL-PROPERTIES; SCRATCH TEST; HARDNESS; STRESS; LOAD AB The adhesion strengths of metal/ceramic, metal/polymer, and polymer/polymer interfaces have been characterized using the continuous microscratch technique. In these experiments, a conical diamond indenter was driven simultaneously into a thin film at a rate of 15 nm/s and across the film surface at a rate of 0.5 mu m/s until a load drop or other discontinuity occurred, indicating film failure. The critical load at failure of the thin film was taken as a measure of the adhesion strength. For metal/ceramic systems such as Cr thin films on Al2O3, and for diamond-like-carbon (DLC) films on glass, clear load drops provided an accurate measure of the adhesion strengths. For metal/polymer systems such as Cu thin films on PET, a change in the loading pattern and periodic cracking events along the scratch track provided evidence of film delamination. For DLC films on polycarbonate substrates, the carbon thin film cracked before it delaminated. For bulk polymers such as polycarbonate and polystyrene/polypropylene, crack growth occurred by a stick-slip mechanism. Using a model developed in an earlier paper, the practical work of adhesion for the Cr/Al2O3 system was determined to be 0.09 J/m(2) and that for the DLC/polycarbonate system was 0.05 J/m(2). The fracture toughnesses of the polycarbonate and polystyrene were 0.81 and 0.2 MPa m(1/2), respectively. These numbers are in good agreement with those obtained by other methods for these systems. C1 UNIV MINNESOTA,DEPT CHEM ENGN & MAT SCI,MINNEAPOLIS,MN 55455. USA,MAT TECHNOL LAB,WATERTOWN,MA 02172. UNIV MINNESOTA,DEPT GEOL & GEOPHYS,MINNEAPOLIS,MN 55455. NR 25 TC 18 Z9 18 U1 2 U2 14 PU VSP BV PI ZEIST PA PO BOX 346, 3700 AH ZEIST, NETHERLANDS SN 0169-4243 J9 J ADHES SCI TECHNOL JI J. Adhes. Sci. Technol. PY 1993 VL 7 IS 12 BP 1279 EP 1292 DI 10.1163/156856193X00105 PG 14 WC Engineering, Chemical; Materials Science, Multidisciplinary; Mechanics SC Engineering; Materials Science; Mechanics GA MQ145 UT WOS:A1993MQ14500003 ER PT J AU BIRX, DL LOOMIS, L SITZ, K VANCOTT, T KERSEY, K TENCER, K MANN, D BURKE, DS REDFIELD, RR AF BIRX, DL LOOMIS, L SITZ, K VANCOTT, T KERSEY, K TENCER, K MANN, D BURKE, DS REDFIELD, RR TI IMMUNOLOGICAL RESILIENCE OF HIV-INFECTED PATIENTS SO JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT RETROVIRAL RES,ROCKVILLE,MD 20850. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0091-6749 J9 J ALLERGY CLIN IMMUN JI J. Allergy Clin. Immunol. PD JAN PY 1993 VL 91 IS 1 BP 294 EP 294 PN 2 PG 1 WC Allergy; Immunology SC Allergy; Immunology GA KK431 UT WOS:A1993KK43100614 ER PT J AU NASTROM, GD EATON, FD AF NASTROM, GD EATON, FD TI THE COUPLING OF GRAVITY-WAVES AND TURBULENCE AT WHITE SANDS, NEW-MEXICO, FROM VHF RADAR OBSERVATIONS SO JOURNAL OF APPLIED METEOROLOGY LA English DT Article ID MODEL; SPECTRUM AB Doppler spectra taken with the VHF Doppler radar at White Sands Missile Range are used to describe the winds and turbulence for 10 days in March-April 1991. The large power aperture product of this radar provides excellent data coverage in 150-m layers over the entire height range used, about 5-20 km. The results show that gravity-wave activity and small-scale turbulence are significantly enhanced at all levels during times when wind speeds in the troposphere, near 5.6 km (about 500 hPa), are strong. Largest enhancements are found in the lower stratosphere, near 16-18 km, where the mean logC(n)2 is increased by over 10 dB during times of strong winds at low levels. Mean winds, wind shears, and static stability in the lower stratosphere were found to be nearly the same, regardless of wind speeds at low levels. The authors conclude that the enhanced turbulence is due to an effect not described by the local background wind and static stability, and suggest that this effect is upward-propagating gravity waves launched in the troposphere during the periods of strong winds. C1 USA,ATMOSPHER SCI LAB,WHITE SANDS MISSILE RANGE,NM 88002. RP NASTROM, GD (reprint author), ST CLOUD STATE UNIV,DEPT EARTH SCI,720 4TH AVE S,ST CLOUD,MN 56301, USA. NR 16 TC 32 Z9 32 U1 0 U2 0 PU AMER METEOROLOGICAL SOC PI BOSTON PA 45 BEACON ST, BOSTON, MA 02108-3693 SN 0894-8763 J9 J APPL METEOROL JI J. Appl. Meteorol. PD JAN PY 1993 VL 32 IS 1 BP 81 EP 87 DI 10.1175/1520-0450(1993)032<0081:TCOGWA>2.0.CO;2 PG 7 WC Meteorology & Atmospheric Sciences SC Meteorology & Atmospheric Sciences GA KG488 UT WOS:A1993KG48800006 ER PT J AU ALBERT, DG AF ALBERT, DG TI A COMPARISON BETWEEN WAVE-PROPAGATION IN WATER-SATURATED AND AIR-SATURATED POROUS MATERIALS SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID ACOUSTIC SLOW WAVES; DYNAMIC PERMEABILITY; MEDIA; TORTUOSITY; SEDIMENTS; OCEAN; SOUND AB The classical Biot theory [J. Acoust. Soc. Am. 28, 168 (1956)] predicts the existence of three waves that can propagate in a fluid-saturated porous material: A fast compressional wave, a slow compressional wave, and a shear wave. Through use of this theory, propagation characteristics within water-filled and air-filled materials were compared in the 10 Hz-100 kHz band. Numerical calculations show that the ratio of fluid to solid motion for the slow compressional wave is around 2 in water-filled sand, but greater than 300 in air-filled sand. In addition, calculations of plane wave transmission from a fluid into a fluid-saturated porous solid were investigated. The calculations show that when the fluid is water, nearly all of the incident energy is transferred to the reflected wave and to the transmitted fast compressional wave that is traveling mainly in the solid frame. Only a slight frequency dependence occurs in the energy transfer. When the fluid is air, however, the interaction of the waves with the boundary becomes strongly dependent upon frequency, and most of the incident energy is transferred to the reflected wave and to the transmitted slow compressional wave traveling mainly in the pores. These theoretical results justify the different approaches used to treat reflections from porous materials in underwater and aeroacoustics. For reflections, air-filled soil or snow can be approximately modeled as a modified fluid (ignoring motion in the frame) rather than as a viscoelastic solid (ignoring motion in the pores), the approximation commonly used to model saturated undersea sediments. RP ALBERT, DG (reprint author), USA,COLD REG RES & ENGN LAB,72 LYME RD,HANOVER,NH 03755, USA. NR 36 TC 44 Z9 44 U1 2 U2 8 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0021-8979 J9 J APPL PHYS JI J. Appl. Phys. PD JAN 1 PY 1993 VL 73 IS 1 BP 28 EP 36 DI 10.1063/1.354035 PG 9 WC Physics, Applied SC Physics GA KE714 UT WOS:A1993KE71400006 ER PT J AU DOUGLAS, AA WAGER, JF MORTON, DC KOH, JB HOGH, CP AF DOUGLAS, AA WAGER, JF MORTON, DC KOH, JB HOGH, CP TI EVIDENCE FOR SPACE-CHARGE IN ATOMIC LAYER EPITAXY ZNS-MN ALTERNATING-CURRENT THIN-FILM ELECTROLUMINESCENT DEVICES SO JOURNAL OF APPLIED PHYSICS LA English DT Article ID SIMPLE-MODEL; HYSTERETIC BEHAVIOR AB Electrical and optical measurements of ZnS:Mn alternating-current thin-film electroluminescent (ACTFEL) devices grown by atomic layer epitaxy provide evidence for the existence of space charge within the bulk ZnS layer. Blue luminescence is observed during the falling edge of an applied voltage pulse when the ACTFEL device is operated at low temperature. This blue luminescence is attributed to donor-acceptor pair radiative recombination in which chlorine is identified as the donor and a zinc vacancy as the acceptor. This luminescence identification leads to determination of the origin of space charge as arising from impact ionization of the zinc vacancy. C1 USA,LAB COMMAND,ELECTR TECHNOL & DEVICES LAB,FT MONMOUTH,NJ 07703. VITRON INC,EATONTOWN,NJ 07724. RP DOUGLAS, AA (reprint author), OREGON STATE UNIV,CTR ADV MAT RES,DEPT ELECT & COMP ENGN,CORVALLIS,OR 97330, USA. NR 16 TC 28 Z9 28 U1 0 U2 0 PU AMER INST PHYSICS PI WOODBURY PA CIRCULATION FULFILLMENT DIV, 500 SUNNYSIDE BLVD, WOODBURY, NY 11797-2999 SN 0021-8979 J9 J APPL PHYS JI J. Appl. Phys. PD JAN 1 PY 1993 VL 73 IS 1 BP 296 EP 299 DI 10.1063/1.353903 PG 4 WC Physics, Applied SC Physics GA KE714 UT WOS:A1993KE71400040 ER PT J AU ZHUANG, J DROMA, T SUN, S JANES, C MCCULLOUGH, RE MCCULLOUGH, RG CYMERMAN, A HUANG, SY REEVES, JT MOORE, LG AF ZHUANG, J DROMA, T SUN, S JANES, C MCCULLOUGH, RE MCCULLOUGH, RG CYMERMAN, A HUANG, SY REEVES, JT MOORE, LG TI HYPOXIC VENTILATORY RESPONSIVENESS IN TIBETAN COMPARED WITH HAN RESIDENTS OF 3,658-M SO JOURNAL OF APPLIED PHYSIOLOGY LA English DT Article DE VENTILATION; CONTROL OF BREATHING; HYPERCAPNIA; HYPOXIA; HYPOXIC VENTILATORY DEPRESSION ID CHRONIC MOUNTAIN-SICKNESS; PULMONARY GAS-EXCHANGE; HIGH-ALTITUDE; RESPIRATORY ADAPTATION; SHERPAS AB Lifelong high-altitude residents of North and South America acquire blunted hypoxic ventilatory responses and exhibit decreased ventilation compared with acclimatized newcomers. The ventilatory characteristics of Himalayan high-altitude residents are of interest in the light of their reportedly lower hemoglobin levels and legendary exercise performance. Until recently, Sherpas have been the only Himalayan population available for study. To determine whether Tibetans exhibited levels of ventilation and hypoxic ventilatory drives that were as great as acclimatized newcomers, we compared 27 lifelong Tibetan residents of Lhasa, Tibet, China (3,658 m) with 30 acclimatized Han (''Chinese'') newcomers matched for age, body size, and extent of exercise training. During room air breathing, minute ventilation was greater in the Tibetan than in the Han young men because of an increased respiratory frequency, but arterial O2 saturation and end-tidal PCO2 did not differ, indicating similar levels of effective alveolar ventilation. The Tibetan subjects had higher hypoxic ventilatory response shape parameter A values and hypercapnic ventilatory responsiveness than the Han subjects. Among the Han subjects, duration of high-altitude residence correlated with the degree of blunting of the hypoxic ventilatory drive. Paradoxically, hyperoxia (inspired O2 fraction 0.70) increased minute ventilation and decreased end-tidal PCO2 in the Tibetan but not in the Han men. We concluded that lifelong Tibetan residents of high altitude neither hypoventilated nor exhibited blunted hypoxic ventilatory responses compared with acclimatized Han newcomers, suggesting that the effects of lifelong high-altitude residence on ventilation and ventilatory response to hypoxia differ in Tibetan compared with other high-altitude populations. C1 UNIV COLORADO,HLTH SCI CTR,CARDIOVASC PULM RES LAB,4200 E 9TH AVE,DENVER,CO 80262. TIBET INST MED SCI,LHASA 850000,PEOPLES R CHINA. SHANGHAI INST PHYSIOL,SHANGHAI,PEOPLES R CHINA. UNIV COLORADO,DEPT ANTHROPOL,DENVER,CO 80217. USA,ENVIRONM MED RES INST,NATICK,MA 01760. FU NHLBI NIH HHS [HL-14985]; NICHD NIH HHS [HD-000681] NR 43 TC 84 Z9 92 U1 2 U2 10 PU AMER PHYSIOLOGICAL SOC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 8750-7587 J9 J APPL PHYSIOL JI J. Appl. Physiol. PD JAN PY 1993 VL 74 IS 1 BP 303 EP 311 PG 9 WC Physiology; Sport Sciences SC Physiology; Sport Sciences GA KJ480 UT WOS:A1993KJ48000042 PM 8444707 ER PT J AU FREY, MAB MADER, TH BAGIAN, JP CHARLES, JB MEEHAN, RT AF FREY, MAB MADER, TH BAGIAN, JP CHARLES, JB MEEHAN, RT TI CEREBRAL BLOOD VELOCITY AND OTHER CARDIOVASCULAR-RESPONSES TO 2 DAYS OF HEAD-DOWN TILT SO JOURNAL OF APPLIED PHYSIOLOGY LA English DT Article DE TRANSCRANIAL DOPPLER; HEART RATE; CARDIAC OUTPUT; ARTERIAL PRESSURE; INTRAOCULAR PRESSURE; RETINAL VESSEL DIAMETER ID INTRAOCULAR-PRESSURE; FLOW AB Space-flight induces a cephalad redistribution of fluid volume and blood flow within the human body, and space motion sickness, which is a problem during the first few days of spaceflight, could be related to these changes in fluid status and in blood flow of the cerebrum and vestibular system. To evaluate possible changes in cerebral blood flow during simulated weightlessness, we measured blood velocity in the middle cerebral artery (MCA) along with retinal vascular diameters, intraocular pressure, impedance cardiography, and sphygmomanometry on nine men (26.2 +/- 6.6 yr) morning and evening for 2 days during continuous 10-degrees head-down tilt (HDT). When subjects went from seated to head-down bed rest, their heart rate and retinal diameters decreased, and intraocular pressures increased. After 48 h of HDT, blood flow velocity in the MCA was decreased and thoracic impedance was increased, indicating less fluid in the thorax. Percent changes in blood flow velocities in the MCA after 48 h of HDT were inversely correlated with percent changes in retinal vascular diameters. Blood flow velocities in the MCA were inversely correlated (intersubject) with arterial pressures and retinal vascular diameters. Heart rate, stroke volume, cardiac output, systolic arterial pressure, and at times pulse pressure and blood flow velocities in the MCA were greater in the evening. Total peripheral resistance was higher in the morning. Although cerebral blood velocity is reduced after subjects are head down for 2 days, the inverse relationship with retinal vessel diameters, which have control analogous to that of cerebral vessels, indicates cerebral blood flow is not reduced. C1 USA,MADIGAN ARMY MED CTR,TACOMA,WA 98493. UNIV SPACE RES ASSOC,HOUSTON,TX 77058. NASA,LYNDON B JOHNSON SPACE CTR,HOUSTON,TX 77058. UNIV TEXAS,MED BRANCH,MED BRANCH,DEPT INTERNAL MED,GALVESTON,TX 77550. FU NCRR NIH HHS [MOI RR-00073] NR 27 TC 40 Z9 47 U1 0 U2 5 PU AMER PHYSIOLOGICAL SOC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 8750-7587 J9 J APPL PHYSIOL JI J. Appl. Physiol. PD JAN PY 1993 VL 74 IS 1 BP 319 EP 325 PG 7 WC Physiology; Sport Sciences SC Physiology; Sport Sciences GA KJ480 UT WOS:A1993KJ48000044 PM 8444709 ER PT J AU KRAEMER, WJ DZIADOS, JE MARCHITELLI, LJ GORDON, SE HARMAN, EA MELLO, R FLECK, SJ FRYKMAN, PN TRIPLETT, NT AF KRAEMER, WJ DZIADOS, JE MARCHITELLI, LJ GORDON, SE HARMAN, EA MELLO, R FLECK, SJ FRYKMAN, PN TRIPLETT, NT TI EFFECTS OF DIFFERENT HEAVY-RESISTANCE EXERCISE PROTOCOLS ON PLASMA BETA-ENDORPHIN CONCENTRATIONS SO JOURNAL OF APPLIED PHYSIOLOGY LA English DT Article DE ANAEROBIC; OPIOID PEPTIDES; CREATINE KINASE; LACTATE; CORTISOL; AMMONIA ID CORTISOL RESPONSES; CREATINE-KINASE; MUSCLE DAMAGE; HUMANS; BLOOD; ADRENOCORTICOTROPIN; INTENSITY; CATECHOLAMINES; DURATION; CELLS AB To examine the changes of plasma beta-endorphin (beta-EP) concentrations in response to various heavy-resistance exercise protocols, eight healthy male subjects randomly performed each of six heavy-resistance exercise protocols, which consisted of identically ordered exercises carefully designed to control for the repetition maximum (RM) resistance (5 vs. 10 RM), rest period length (1 vs. 3 min), and total work (joules). Plasma beta-EP, ammonia, whole blood lactate and serum cortisol, creatine kinase, urea, and creatinine were determined preexercise, midexercise, immediately postexercise, and at various time points after the exercise session (5 min-48 h), depending on the specific blood variable examined. Only the high total work-exercise protocol [1 min rest, 10 RM load (H10/l)] demonstrated significant increases in plasma beta-EP and serum cortisol at midexercise and 0, 5, and 15 min postexercise. Increases in lactate were observed after all protocols, but the largest increases were observed after the H10/1 protocol. Within the H10/1 protocol, lactate concentrations were correlated (r = 0.82, P < 0.05) with plasma beta-EP concentrations. Cortisol increases were significantly correlated (r = 0.84) with 24-h peak creatine kinase values. The primary finding of this investigation was that beta-EP responds differently to various heavy-resistance exercise protocols. In heavy-resistance exercise, it appears that the duration of the force production and the length of the rest periods between sets are key exercise variables that influence increases in plasma beta-EP and serum cortisol concentrations. Furthermore the H10/1 protocol's significant challenge to the acid-base status of the blood, due to marked increases in whole blood lactate, may be associated with mechanisms modulating peripheral blood concentrations of beta-EP and cortisol. C1 USA,ENVIRONM MED RES INST,NATICK,MA 01760. US OLYMPIC COMM,DIV SPORTS SCI,COLORADO SPRINGS,CO 80909. RP KRAEMER, WJ (reprint author), PENN STATE UNIV,CTR SPORTS MED,117 ANN BLDG,UNIV PK,PA 16802, USA. NR 37 TC 83 Z9 84 U1 0 U2 3 PU AMER PHYSIOLOGICAL SOC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 8750-7587 J9 J APPL PHYSIOL JI J. Appl. Physiol. PD JAN PY 1993 VL 74 IS 1 BP 450 EP 459 PG 10 WC Physiology; Sport Sciences SC Physiology; Sport Sciences GA KJ480 UT WOS:A1993KJ48000062 PM 8444727 ER PT J AU MADSEN, JD AF MADSEN, JD TI GROWTH AND BIOMASS ALLOCATION PATTERNS DURING WATER-HYACINTH MAT DEVELOPMENT SO JOURNAL OF AQUATIC PLANT MANAGEMENT LA English DT Article; Proceedings Paper CT 32nd Annual Meeting of the Aquatic-Plant-Management-Society and the International Symposium on the Biology and Management of Aquatic Plants CY JUL 12-16, 1992 CL DAYTONA BEACH, FL SP AQUAT MANAGEMENT SOC DE MAT FORMATION; DENSITY-DEPENDENCE; PHENOLOGY; SELF-THINNING; EICHHORNIA CRASSIPES (MART) SOLMS AB Two experiments in ponds were conducted to determine growth rates and biomass allocation patterns of waterhyacinth during different life cycle and developmental stages and seasons. Experimental ponds were maintained below a pH of 8.5, and one pond was amended with 11.4 kg of nitrogen per week. Plants were separated into constituent parts after sampling, dried, and weighed to determine biomass. Early in development, plants allocated most production to root material, with little increase in average plant size. Once a critical density was reached, plants increased in average weight and production of daughter plants, with reduced allocation to roots. At peak density, daughter plant production was reduced, but average plant size increased rapidly, resulting in plant mortality. Waterhyacinth exhibited a positive density dependent growth pattern early in development, and switched to the negative density dependent pattern after peak density was achieved. RP MADSEN, JD (reprint author), USAE,WATERWAYS EXPT STN,LEWISVILLE AQUAT ECOSYST RES FACIL,RR 3 BOX 446,LEWISVILLE,TX 75056, USA. NR 4 TC 6 Z9 8 U1 1 U2 2 PU AQUATIC PLANT MANAGEMENT SOC, INC PI CLERMONT PA PO BOX 121086, CLERMONT, FL 34712-1086 SN 0146-6623 J9 J AQUAT PLANT MANAGE JI J. Aquat. Plant Manage. PD JAN PY 1993 VL 31 BP 134 EP 137 PG 4 WC Plant Sciences; Marine & Freshwater Biology SC Plant Sciences; Marine & Freshwater Biology GA MU079 UT WOS:A1993MU07900030 ER PT J AU METHE, BA SORACCO, RJ MADSEN, JD BOYLEN, CW AF METHE, BA SORACCO, RJ MADSEN, JD BOYLEN, CW TI SEED PRODUCTION AND GROWTH OF WATERCHESTNUT AS INFLUENCED BY CUTTING SO JOURNAL OF AQUATIC PLANT MANAGEMENT LA English DT Article; Proceedings Paper CT 32nd Annual Meeting of the Aquatic-Plant-Management-Society and the International Symposium on the Biology and Management of Aquatic Plants CY JUL 12-16, 1992 CL DAYTONA BEACH, FL SP AQUAT MANAGEMENT SOC DE AQUATIC MACROPHYTE; WATER CALTROP; AQUATIC PLANT CONTROL; TRAPA NATANS; AQUATIC PLANT CUTTING AB A major infestation of waterchestnut (Trapa natans L.) in a reservoir in New York State was studied to evaluate the efficacy of air boat cutting as a possible control measure. A measure of the status of the seed bank through sediment core analysis showed that deposition of new seeds in a treatment site was reduced to no net gain of seeds versus an average of 170 seeds/m(2) added to the seed bank in an untreated site. Results from seed-fall collection baskets placed in two untreated sites revealed new deposition of 180 seeds/m(2) and 143 2 seeds/m(2), respectively, which corroborated the results from Sediment core data. Cut rosette fragments, produced by the cuffing operation, were compared to undisturbed whole plants for vigor and seed production. Both vigor and seed production rates were less than those of intact plants. C1 US ARMY ENGINEER WATERWAYS EXPT STN,LEWISVILLE,TX 75056. RP METHE, BA (reprint author), RENSSELAER POLYTECH INST,RENSSELAER FRESH WATER INST,MRC 203,TROY,NY 12180, USA. NR 4 TC 6 Z9 6 U1 0 U2 4 PU AQUATIC PLANT MANAGEMENT SOC, INC PI CLERMONT PA PO BOX 121086, CLERMONT, FL 34712-1086 SN 0146-6623 J9 J AQUAT PLANT MANAGE JI J. Aquat. Plant Manage. PD JAN PY 1993 VL 31 BP 154 EP 157 PG 4 WC Plant Sciences; Marine & Freshwater Biology SC Plant Sciences; Marine & Freshwater Biology GA MU079 UT WOS:A1993MU07900035 ER PT J AU NELSON, LS NETHERLAND, MD GETSINGER, KD AF NELSON, LS NETHERLAND, MD GETSINGER, KD TI BENSULFURON METHYL ACTIVITY ON EURASIAN WATERMILFOIL SO JOURNAL OF AQUATIC PLANT MANAGEMENT LA English DT Article; Proceedings Paper CT 32nd Annual Meeting of the Aquatic-Plant-Management-Society and the International Symposium on the Biology and Management of Aquatic Plants CY JUL 12-16, 1992 CL DAYTONA BEACH, FL SP AQUAT MANAGEMENT SOC DE HERBICIDE; SULFONYLUREA; EXPOSURE TIME; MYRIOPHYLLUM SPICATUM L ID HYDRILLA AB The efficacy of bensulfuron methyl (BSM) at 40 concentration and exposure time combinations was evaluated on Eurasian watermilfoil (Myriophyllum spicatum L.) under controlled-environment conditions. BSM concentrations ranged from 0 to 4600 mu g/l; exposure times ranged from 7 to 42 days. Efficacy was based on shoot and root biomass harvested at the conclusion of each experiment. Herbicide injury was evident 1 week after application on all treatments, and symptoms included leaf chlorosis, deformed leaves on shoot tips, downward bending of leaves at upper nodes, stem necrosis, and formation of axillary buds. Following 7-, 14-, 21-, 28-, 35-, and 42-day exposure periods at concentrations ranging from 10 to 4600 mu g/l, biomass was reduced 10 to 90% compared to untreated plants. Increasing exposure time was more efficacious than increasing concentration. BSM concentrations <10 mu g/l did not significantly reduce growth. Effects on roots were variable depending on concentration and plant age. Only treatments of 230 mu g/l and higher inhibited root growth on plants grown for 3 weeks prior to treatment. Regrowth emerged from rootcrowns, axillary buds, and injured shoot apices, and was evident 1 to 2 weeks following completion of the exposure period and removal of the BSM-treated water. Plant death was not achieved at the concentrations and exposure times tested in these studies. RP NELSON, LS (reprint author), USAE,WATERWAYS EXPT STN,ENVIRONM LAB,3909 HALLS FERRY RD,VICKSBURG,MS 39180, USA. NR 20 TC 5 Z9 5 U1 1 U2 3 PU AQUATIC PLANT MANAGEMENT SOC, INC PI CLERMONT PA PO BOX 121086, CLERMONT, FL 34712-1086 SN 0146-6623 J9 J AQUAT PLANT MANAGE JI J. Aquat. Plant Manage. PD JAN PY 1993 VL 31 BP 179 EP 185 PG 7 WC Plant Sciences; Marine & Freshwater Biology SC Plant Sciences; Marine & Freshwater Biology GA MU079 UT WOS:A1993MU07900040 ER PT J AU NETHERLAND, MD GETSINGER, KD TURNER, EG AF NETHERLAND, MD GETSINGER, KD TURNER, EG TI FLURIDONE CONCENTRATION AND EXPOSURE TIME REQUIREMENTS FOR CONTROL OF EURASIAN WATERMILFOIL AND HYDRILLA SO JOURNAL OF AQUATIC PLANT MANAGEMENT LA English DT Article; Proceedings Paper CT 32nd Annual Meeting of the Aquatic-Plant-Management-Society and the International Symposium on the Biology and Management of Aquatic Plants CY JUL 12-16, 1992 CL DAYTONA BEACH, FL SP AQUAT MANAGEMENT SOC DE AQUATIC WEEDS; HERBICIDE; MYRIOPHYLLUM SPICATUM; HYDRILLA VERTICILLATA AB Fluridone concentration and exposure time requirements were evaluated for Eurasian watermilfoil (Myriophyllum spicatum L.) and hydrilla (Hydrilla verticillata (L.f.) Royle) under controlled-environment conditions. Results indicated that fluridone effectively inhibited growth and reduced biomass at rates of 12, 24 and 48 mu g/l. Shoot and root biomass and total chlorophyll were reduced from 70 to 98% following 30-, 60- and 90-days exposures to fluridone. However, removal of fluridone at 30 and 60 days resulted in extensive regrowth following a 30-day recovery period. One exception was milfoil exposed to 48 mu g/l for 60 days which was reduced by approximately 98% with no evidence of regrowth. The 48-mu g/l treatment often resulted in greater biomass reduction in both species than the other rates; however, no significant differences were noted between the treatment rates of 12 and 24 mu g/l. Results indicate that maintaining fluridone concentrations for >60 days at rates as low as 12 mu g/l is critical for successful fluridone treatments. C1 ASCI CORP,VICKSBURG,MS 39180. RP NETHERLAND, MD (reprint author), USAE,WATERWAYS EXPT STN,ENVIRONM LAB,3909 HALLS FERRY RD,VICKSBURG,MS 39180, USA. NR 17 TC 33 Z9 36 U1 2 U2 6 PU AQUATIC PLANT MANAGEMENT SOC, INC PI CLERMONT PA PO BOX 121086, CLERMONT, FL 34712-1086 SN 0146-6623 J9 J AQUAT PLANT MANAGE JI J. Aquat. Plant Manage. PD JAN PY 1993 VL 31 BP 189 EP 194 PG 6 WC Plant Sciences; Marine & Freshwater Biology SC Plant Sciences; Marine & Freshwater Biology GA MU079 UT WOS:A1993MU07900042 ER PT J AU CHAMBERS, PA BARKO, JW SMITH, CS AF CHAMBERS, PA BARKO, JW SMITH, CS TI EVALUATION OF INVASIONS AND DECLINES OF SUBMERSED AQUATIC MACROPHYTES SO JOURNAL OF AQUATIC PLANT MANAGEMENT LA English DT Editorial Material AB During the past 60 yr, sightings of aquatic macrophyte species in geographic regions where they had previously not been found have occurred with increasing frequency, apparently due to both greater dispersal of the plants as a result of human activities as well as better documentation of plant distribution. Intercontinental invasions, such as Myriophyllum spicatum and Hydrilla into North America, Elodea canadensis into Europe and Elodea nuttallii, Egeria densa and Cabomba caroliniana into Japan, have generally been well documented. However, the spread of an exotic species across a continent after its initial introduction (e.g., Potamogeton crispus in North America) or the expansion of a species native to a continent into hitherto unexploited territory (e.g.,the expansion of the North American native Myriophyllum heterophyllum into New England) have received little attention. Natural declines in aquatic macrophyte communities have also received little scientific study although there are many accounts of macrophyte declines. The best-documented example comes from the marine literature where extensive declines of eelgrass (Zostera) occurred in the 1930s along the Atlantic coast due to a pathogenic marine slime mold (''wasting disease''). The aim of this workshop was to identify examples of invasions or natural declines of aquatic macrophyte species throughout the world and assess the importance of environmental factors in their control. Forty-five scientists and aquatic plant managers from ten countries participated in the workshop. Eleven of the participants contributed written evaluations of species invasions and declines in their geo-graphic region. These were distributed to registered participants prior to the meeting and served as the starting-point of workshop discussions. To address the topics raised in the working papers, the participants divided into four working groups to evaluate: 1. Environmental controls of species invasions. 2. Biotic controls of species declines. 3. Abiotic controls of species declines. 4. Impact of management practices on macrophyte invasions or declines. Each working group was asked to identify existing evidence, the need for additional evidence and management implications of their topics and then requested to discuss their findings with the entire workshop at the conclusion of discussions. C1 USAE,WATERWAYS EXPT STN,VICKSBURG,MS 39180. US FISH & WILDLIFE SERV,TECH CTR,ONLASKA,WI 54650. RP CHAMBERS, PA (reprint author), ENVIRONM CANADA,NATL HYDROL RES INST,11 INNOVAT BLVD,SASKATOON S7N 3H5,SK,CANADA. NR 0 TC 25 Z9 25 U1 3 U2 24 PU AQUATIC PLANT MANAGEMENT SOC, INC PI CLERMONT PA PO BOX 121086, CLERMONT, FL 34712-1086 SN 0146-6623 J9 J AQUAT PLANT MANAGE JI J. Aquat. Plant Manage. PD JAN PY 1993 VL 31 BP 218 EP 220 PG 3 WC Plant Sciences; Marine & Freshwater Biology SC Plant Sciences; Marine & Freshwater Biology GA MU079 UT WOS:A1993MU07900049 ER PT J AU FORNO, IW COFRANCESCO, AF AF FORNO, IW COFRANCESCO, AF TI NEW FRONTIERS IN BIOCONTROL SO JOURNAL OF AQUATIC PLANT MANAGEMENT LA English DT Editorial Material C1 USAE,WATERWAYS EXPT STN,VICKSBURG,MS 39180. RP FORNO, IW (reprint author), CSIRO,DIV ENTOMOL,PRIVATE MAIL BAG 3,INDOOROOPILLY,QLD 4068,AUSTRALIA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AQUATIC PLANT MANAGEMENT SOC, INC PI CLERMONT PA PO BOX 121086, CLERMONT, FL 34712-1086 SN 0146-6623 J9 J AQUAT PLANT MANAGE JI J. Aquat. Plant Manage. PD JAN PY 1993 VL 31 BP 222 EP 224 PG 3 WC Plant Sciences; Marine & Freshwater Biology SC Plant Sciences; Marine & Freshwater Biology GA MU079 UT WOS:A1993MU07900051 ER PT J AU HEEKIN, RD CALLAGHAN, JJ HOPKINSON, WJ SAVORY, CG XENOS, JS AF HEEKIN, RD CALLAGHAN, JJ HOPKINSON, WJ SAVORY, CG XENOS, JS TI THE POROUS-COATED ANATOMIC TOTAL HIP-PROSTHESIS, INSERTED WITHOUT CEMENT - RESULTS AFTER 5 TO 7 YEARS IN A PROSPECTIVE-STUDY SO JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME LA English DT Article ID 10-YEAR FOLLOW-UP; FEMORAL COMPONENT; BONE INGROWTH; REPLACEMENT; ARTHROPLASTY AB The results of 100 primary arthroplasties with a porous-coated anatomic total hip prosthesis that were performed consecutively in ninety-one patients were followed prospectively for five to seven years after the operation or until death. Clinical Harris hip ratings and anteroposterior and lateral radiographs were made preoperatively, several times in the first postoperative year, and at annual intervals thereafter. Average sequential hip ratings were maintained between 92 and 93 points during the follow-up interval. Pain in the thigh, which did not limit function, was recorded at the yearly examinations from the first to the fifth year. After one year, 18 per cent of the thighs were painful, and in succeeding years, 19 per cent, 23 per cent, 26 per cent, and 15 per cent were painful. Radiographs demonstrated that the fixation of the femoral component was by ingrowth of bone in 94 per cent of the hips, by stable fibrous fixation in 1 per cent, and by unstable fibrous fixation in 5 per cent, according to the criteria of Engh et al. By five years, 6 per cent of the acetabular components had migrated, and 5 per cent of the femoral components had subsided. Two acetabular components had been revised, and one revision of a femoral component was pending. The evaluated device was an early-generation prosthesis that was designed for insertion without the use of cement. Further study is necessary to determine the long-term durability of the prosthesis-bone interface. C1 WALTER REED ARMY MED CTR,ORTHOPAED SERV,WASHINGTON,DC 20307. NR 37 TC 174 Z9 175 U1 0 U2 3 PU JOURNAL BONE JOINT SURGERY INC PI NEEDHAM PA 20 PICKERING ST, NEEDHAM, MA 02192 SN 0021-9355 J9 J BONE JOINT SURG AM JI J. Bone Joint Surg.-Am. Vol. PD JAN PY 1993 VL 75A IS 1 BP 77 EP 91 PG 15 WC Orthopedics; Surgery SC Orthopedics; Surgery GA KH729 UT WOS:A1993KH72900010 PM 8419394 ER PT J AU BERNHARDT, M HYNES, RA BLUME, HW WHITE, AA AF BERNHARDT, M HYNES, RA BLUME, HW WHITE, AA TI CERVICAL SPONDYLOTIC MYELOPATHY SO JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME LA English DT Review ID SPINAL-CORD; SURGICAL-TREATMENT; STENOSIS; FUSION; COMPLICATIONS; COMPRESSION; ISCHEMIA C1 EISENHOWER ARMY MED CTR,DEPT ORTHOPAED SURG,FT GORDON,GA 30905. BETH ISRAEL HOSP,BOSTON,MA 02215. RP BERNHARDT, M (reprint author), DICKSON DIVELEY ORTHOPAED CLIN,SUITE 610,MED PLAZA BLDG,4320 WORNALL RD,KANSAS CITY,MO 64111, USA. NR 79 TC 104 Z9 119 U1 0 U2 0 PU JOURNAL BONE JOINT SURGERY INC PI NEEDHAM PA 20 PICKERING ST, NEEDHAM, MA 02192 SN 0021-9355 J9 J BONE JOINT SURG AM JI J. Bone Joint Surg.-Am. Vol. PD JAN PY 1993 VL 75A IS 1 BP 119 EP 128 PG 10 WC Orthopedics; Surgery SC Orthopedics; Surgery GA KH729 UT WOS:A1993KH72900015 PM 8419381 ER PT J AU ARONSON, NE AMEGIN, GP AF ARONSON, NE AMEGIN, GP TI POSTERIOR SUBCAPSULAR CATARACTS ASSOCIATED WITH MEGESTROL-ACETATE THERAPY SO JOURNAL OF CATARACT AND REFRACTIVE SURGERY LA English DT Article DE CATARACT; HUMAN IMMUNODEFICIENCY VIRUS; MEGESTROL AB Megestrol acetate, used for eight weeks as an appetite stimulant in a man infected with human immunodeficiency virus, was associated with the development of bilateral posterior subcapsular cataracts. We propose that the glucocorticoid properties of megestrol were contributory. Complicating this association, the patient developed cytomegalovirus retinitis approximately six weeks after the cataracts were recognized. RP ARONSON, NE (reprint author), WALTER REED ARMY MED CTR,INFECT DIS SERV,WASHINGTON,DC 20307, USA. NR 0 TC 2 Z9 2 U1 0 U2 0 PU AMER SOC CATARACT REFRACTIVE SURGERY PI FAIRFAX PA 4000 LEGATO RD, SUITE 850, FAIRFAX, VA 22030 SN 0886-3350 J9 J CATARACT REFR SURG JI J. Cataract. Refract. Surg. PD JAN PY 1993 VL 19 IS 1 BP 90 EP 91 PG 2 WC Ophthalmology; Surgery SC Ophthalmology; Surgery GA KH687 UT WOS:A1993KH68700021 PM 8426332 ER PT J AU CHATFIELD, DC FRIEDMAN, RS LYNCH, GC TRUHLAR, DG SCHWENKE, DW AF CHATFIELD, DC FRIEDMAN, RS LYNCH, GC TRUHLAR, DG SCHWENKE, DW TI THE NATURE AND ROLE OF QUANTIZED TRANSITION-STATES IN THE ACCURATE QUANTUM DYNAMICS OF THE REACTION O+H2-]OH+H SO JOURNAL OF CHEMICAL PHYSICS LA English DT Review ID MECHANICAL REACTION PROBABILITIES; POTENTIAL-ENERGY SURFACE; CUMULATIVE REACTION PROBABILITIES; CHEMICAL-REACTIONS; REACTION-RATES; PHOTODETACHMENT SPECTRUM; RATE CONSTANTS; SEMICLASSICAL QUANTIZATION; TUNNELING CALCULATIONS; COLLINEAR REACTIONS AB Accurate quantum mechanical dynamics calculations are reported for the reaction probabilities of O(3P) + H-2 --> OH + H with zero total angular momentum on a single potential energy surface. The results show that the reactive flux is gated by quantized transition states up to the highest energy studied, which corresponds to a total energy of 1.90 eV. The quantized transition states are assigned and compared to vibrationally adiabatic barrier maxima; their widths and transmission coefficients are determined; and they are classified as variational, supernumerary of the first kind, and supernumerary of the second kind. Their effects on state-selected and state-to-state reactivity are discussed in detail. C1 UNIV MINNESOTA, ARMY HIGH PERFORMANCE COMP RES CTR, MINNEAPOLIS, MN 55455 USA. NASA, AMES RES CTR, MOFFETT FIELD, CA 94035 USA. RP UNIV MINNESOTA, INST SUPERCOMP, DEPT CHEM, MINNEAPOLIS, MN 55455 USA. RI schwenke, david/I-3564-2013; Truhlar, Donald/G-7076-2015 OI Truhlar, Donald/0000-0002-7742-7294 NR 114 TC 56 Z9 57 U1 4 U2 7 PU AMER INST PHYSICS PI MELVILLE PA 1305 WALT WHITMAN RD, STE 300, MELVILLE, NY 11747-4501 USA SN 0021-9606 EI 1089-7690 J9 J CHEM PHYS JI J. Chem. Phys. PD JAN 1 PY 1993 VL 98 IS 1 BP 342 EP 362 DI 10.1063/1.464627 PG 21 WC Chemistry, Physical; Physics, Atomic, Molecular & Chemical SC Chemistry; Physics GA KF406 UT WOS:A1993KF40600040 ER PT J AU TSENG, YCL LAHIRI, S JACKSON, S BURMAN, KD WARTOFSKY, L AF TSENG, YCL LAHIRI, S JACKSON, S BURMAN, KD WARTOFSKY, L TI ENDOTHELIN BINDING TO RECEPTORS AND ENDOTHELIN PRODUCTION BY HUMAN THYROID FOLLICULAR CELLS - EFFECTS OF TRANSFORMING GROWTH-FACTOR-BETA AND THYROTROPIN SO JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM LA English DT Article ID ATRIAL-NATRIURETIC-PEPTIDE; SMOOTH-MUSCLE CELLS; PARATHYROID CELLS; RAT HYPOTHALAMUS; PITUITARY-GLAND; DNA-SYNTHESIS; C-FOS; RELEASE; EXPRESSION; SECRETION AB Measurable endothelin (ET) was found in serum-free medium of cultured primary thyroid cells derived from human thyroid tissues after 3 days incubation at levels ranging from undetectable to 35 fmol/100,000 cells. Out of 12 thyroid glands studied, 2 responded to transforming growth factor-beta (TGF-beta) treatment with increased ET secretion into medium. Detailed study of cells derived from one of these thyroids showed TGF-beta at 1 ng/ml stimulated ET secretion from 13.7 to 33.3 fmol/100,000 cells after 3 days incubation. Although TSH alone did not significantly modulate ET release into medium, TSH enhanced the stimulatory effect of TGF-beta. A combination of TSH at 1 mU/ml and TGF-beta at 1 ng/ml stimulated ET secretion to 63.8 fmol/100,000 cells after 3 days incubation. Immunostaining studies demonstrated the presence of intracellular immunoreactive ET, largely localized in perinuclear regions, which was greatly stimulated by TSH but not by TGF-beta. These observations suggest that TSH may stimulate only ET synthesis, whereas TGF-beta may stimulate both synthesis and secretion. Binding of [I-125]ET-1 to receptor on thyroid cells was dose-dependently stimulated by TGF-beta (0-10 ng/ml) pretreatment for 3 days. Scatchard analysis of competitive binding data from TGF-beta (1 ng/ml)-treated cells indicated that increased binding was the result of increased receptor number and not increased receptor affinity. TSH (0-10 mU/ml), though not as potent as TGF-beta, also dose-dependently stimulated ET binding. Treatment of thyrocytes with 1 mU/ml TSH for 3 days did not significantly affect ET receptor number or binding affinity. These results illuminate aspects of a possible autocrine regulation of ET in the thyroid gland. C1 WALTER REED ARMY MED CTR, DEPT MED, WASHINGTON, DC 20307 USA. WALTER REED ARMY MED CTR, DEPT CLIN INVEST, WASHINGTON, DC 20307 USA. NR 39 TC 27 Z9 28 U1 0 U2 0 PU ENDOCRINE SOC PI CHEVY CHASE PA 8401 CONNECTICUT AVE, SUITE 900, CHEVY CHASE, MD 20815-5817 USA SN 0021-972X J9 J CLIN ENDOCR METAB JI J. Clin. Endocrinol. Metab. PD JAN PY 1993 VL 76 IS 1 BP 156 EP 161 DI 10.1210/jc.76.1.156 PG 6 WC Endocrinology & Metabolism SC Endocrinology & Metabolism GA LB524 UT WOS:A1993LB52400029 PM 8421082 ER PT J AU MAHER, GM HARTMAN, KR AF MAHER, GM HARTMAN, KR TI DETECTION OF ANTINEUTROPHIL AUTOANTIBODIES BY FLOW-CYTOMETRY - USE OF UNFIXED NEUTROPHILS AS ANTIGENIC TARGETS SO JOURNAL OF CLINICAL LABORATORY ANALYSIS LA English DT Article DE NEUTROPHILS; IMMUNOLOGY; FLOW CYTOMETRY; AUTOIMMUNITY; IMMUNOGLOBULINS; NEUTROPENIA; SYSTEMIC LUPUS ERYTHEMATOSUS; RHEUMATOID ARTHRITIS ID AUTOIMMUNE NEUTROPENIA; ANTIBODIES; CELLS AB Antineutrophil antibodies may be found in the sera of patients with chronic neutropenia as well as in the sera of a variety of patients with neutropenia and associated autoimmune or infectious disorders. We evaluated an immunofluorescent flow cytometric technique for the measurement of antineutrophil antibodies in serum. Sera from patients with suspected immune neutropenia were studied and compared with a group of sera from normal healthy individuals, as well as with sera from patients with rheumatoid arthritis and systemic lupus erythematosus. Of 159 patients with suspected immune neutropenia and a variety of associated clinical disorders, 59 (37%) were found to have evidence for enhanced binding of IgG to normal target neutrophils, interpreted as positive for antineutrophil antibodies. Whereas 0/37 nonneutropenic patients with typical RA had positive results, 51/244 (21%) of sera from nonneutropenic patients with SLE or other collagen vascular disorders showed enhanced IgG binding to neutrophils. Living neutrophils were used to study the effects of cellular activation, and increased antibody binding was observed with certain sera that contained IgG directed against activation-dependent antigens. We found that, under controlled conditions, flow cytometry can be reliably used to detect antineutrophil autoantibodies, with unfixed, living neutrophils as antigenic targets. (C) 1993 Wiley-Liss, Inc.* C1 WALTER REED ARMY INST RES,DEPT HEMATOL,BLDG 40,WASHINGTON,DC 20307. FITZSIMONS ARMY MED CTR,AURORA,CO 80045. NR 26 TC 11 Z9 11 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0887-8013 J9 J CLIN LAB ANAL JI J. Clin. Lab. Anal. PY 1993 VL 7 IS 6 BP 334 EP 340 DI 10.1002/jcla.1860070607 PG 7 WC Medical Laboratory Technology SC Medical Laboratory Technology GA MD085 UT WOS:A1993MD08500006 PM 8277357 ER PT J AU LONG, GW OPRANDY, JJ NARAYANAN, RB FORTIER, AH PORTER, KR NACY, CA AF LONG, GW OPRANDY, JJ NARAYANAN, RB FORTIER, AH PORTER, KR NACY, CA TI DETECTION OF FRANCISELLA-TULARENSIS IN BLOOD BY POLYMERASE CHAIN-REACTION SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Note ID TULAREMIA; IMMUNITY; CHILDREN; MICE AB We developed a polymerase chain reaction-based assay for Francisella tularensis which we evaluated by using spiked blood samples and experimentally infected mice. The assay detected both type A and type B F. tularensis at levels equivalent to one CFU/mul of spiked blood. Results from polymerase chain reaction-based assay of limiting dilutions of blood from mice infected with the live vaccine strain agreed closely with results from blood culture. C1 USN,MED RES INST,INFECT DIS THREAT ASSESSMENT PROGRAM,ROCKVILLE,MD 20852. WALTER REED ARMY INST RES,DEPT CELLULAR IMMUNOL,WASHINGTON,DC 20307. RP LONG, GW (reprint author), JOHNS HOPKINS UNIV,CTR IMMUNIZAT RES,624 N BROADWAY,BALTIMORE,MD 21205, USA. NR 15 TC 68 Z9 73 U1 0 U2 1 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD JAN PY 1993 VL 31 IS 1 BP 152 EP 154 PG 3 WC Microbiology SC Microbiology GA KC718 UT WOS:A1993KC71800031 PM 8417022 ER PT J AU COOPER, MR DEAR, K MCINTYRE, OR OZER, H ELLERTON, J CANELLOS, G BERNHARDT, B DUGGAN, D FARAGHER, D SCHIFFER, C AF COOPER, MR DEAR, K MCINTYRE, OR OZER, H ELLERTON, J CANELLOS, G BERNHARDT, B DUGGAN, D FARAGHER, D SCHIFFER, C TI A RANDOMIZED CLINICAL-TRIAL COMPARING MELPHALAN PREDNISONE WITH OR WITHOUT INTERFERON ALFA-2B IN NEWLY DIAGNOSED PATIENTS WITH MULTIPLE-MYELOMA - A CANCER AND LEUKEMIA GROUP-B STUDY SO JOURNAL OF CLINICAL ONCOLOGY LA English DT Article ID ALPHA-INTERFERON; INVITRO; ASSAY C1 HARVARD UNIV,SCH PUBL HLTH,BOSTON,MA 02115. HARVARD UNIV,SCH MED,DANA FARBER CANC INST,BOSTON,MA 02115. DARTMOUTH COLL,HITCHCOCK MED CTR,HANOVER,NH 03756. UNIV N CAROLINA,CHAPEL HILL,NC 27514. UNIV CALIF SAN DIEGO,SAN DIEGO,CA 92103. CORNELL UNIV,MED CTR,NEW YORK HOSP,NEW YORK,NY 10021. SUNY HLTH SCI CTR,SYRACUSE,NY. WALTER REED ARMY MED CTR,WASHINGTON,DC 20307. UNIV MARYLAND,CTR CANC,BALTIMORE,MD 21201. RP COOPER, MR (reprint author), WAKE FOREST UNIV,BOWMAN GRAY SCH MED,CTR COMPREHENS CANC,300 S HAWTHORNE RD,WINSTON SALEM,NC 27103, USA. FU NCI NIH HHS [CA 04326, CA 03927, CA 33601] NR 23 TC 92 Z9 92 U1 0 U2 1 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0732-183X J9 J CLIN ONCOL JI J. Clin. Oncol. PD JAN PY 1993 VL 11 IS 1 BP 155 EP 160 PG 6 WC Oncology SC Oncology GA KF531 UT WOS:A1993KF53100024 PM 8418228 ER PT J AU MONTALVOPOLK, A KITTLE, PE AF MONTALVOPOLK, A KITTLE, PE TI IMPACTION AND MALFORMATION OF A MAXILLARY CENTRAL INCISOR - SEQUELAE OF TRAUMA SO JOURNAL OF DENTISTRY FOR CHILDREN LA English DT Article C1 USA,DENT ACT,FT KNOX,KY 40121. PEDIAT DENT RESIDENCY PROGRAM,FT LEWIS,WA. NR 8 TC 3 Z9 3 U1 0 U2 0 PU AMER SOC DENTISTRY CHILD PI CHICAGO PA JOHN HANCOCK CENTER, 875 N MICHIGAN AVE, STE 4040, CHICAGO, IL 60611-1901 SN 0022-0353 J9 J DENT CHILD JI J. Dent. Child. PD JAN-FEB PY 1993 VL 60 IS 1 BP 29 EP 32 PG 4 WC Dentistry, Oral Surgery & Medicine; Pediatrics SC Dentistry, Oral Surgery & Medicine; Pediatrics GA KQ125 UT WOS:A1993KQ12500006 ER PT J AU BADGER, GR AF BADGER, GR TI BEHAVIOR MANAGEMENT OF A PATIENT WITH MOBIUS SYNDROME - REPORT OF CASE SO JOURNAL OF DENTISTRY FOR CHILDREN LA English DT Article DE MOBIUS SYNDROME; RESTORATION OF TEETH; GENERAL ANESTHESIA AB A twelve-year old Mobius syndrome patient was successfully examined as an outpatient, using patience, tactile desensitization, and cooperative interaction. Restoration of carious teeth was accomplished, using general anesthesia. Behavioral intervention was successful, thus avoiding an unnecessary hospitalization for examination only. C1 USA,DENT ACT,FT BELVOIR,VA 22060. NR 3 TC 0 Z9 1 U1 0 U2 0 PU AMER SOC DENTISTRY CHILD PI CHICAGO PA JOHN HANCOCK CENTER, 875 N MICHIGAN AVE, STE 4040, CHICAGO, IL 60611-1901 SN 0022-0353 J9 J DENT CHILD JI J. Dent. Child. PD JAN-FEB PY 1993 VL 60 IS 1 BP 60 EP 62 PG 3 WC Dentistry, Oral Surgery & Medicine; Pediatrics SC Dentistry, Oral Surgery & Medicine; Pediatrics GA KQ125 UT WOS:A1993KQ12500013 ER PT J AU LIESKE, CN GEPP, RT MAXWELL, DM CLARK, JH BROOMFIELD, CA BLUMBERGS, P TSENG, CC AF LIESKE, CN GEPP, RT MAXWELL, DM CLARK, JH BROOMFIELD, CA BLUMBERGS, P TSENG, CC TI CHOLINESTERASE STUDIES WITH (R) (+)-(S)(-)-5-(1,3,3-TRIMETHYLINDOLINYL)-N-(1-PHENYLETHYL)CARBAMATE AND (S)(-)-5-(1,3,3-TRIMETHYLINDOLINYL)-N-(1-PHENYLETHYL)CARBAMATE SO JOURNAL OF ENZYME INHIBITION LA English DT Article DE CARBAMATES; STEREOISOMERS; ACETYLCHOLINESTERASE; INHIBITION ID HUPERZINE-A; ACETYLCHOLINESTERASE; INHIBITION; (+)-PHYSOSTIGMINE; ALKALOIDS AB A limited number of carbamates have been found useful for treatment of cholinergic symptoms with pyridostigmine and physostigmine being the main focus. In recent years 5-(1,3,3-trimethylindolinyl)N,N-dimethylcarbamate (I) has received considerable attention in the Chinese literature for a similar role. We report on the first synthesis of stereoisomers of an analog of (I). The isomers prepared were (R)( + )-5-(1,3,3-trimethylindolinyl)-N-(1-phenylethyl)carbamate (II) and (S)(-)-5-(1,3,3-trimethylindolinyl)-N-(1-phenylethyl)carbamate (III). The pK(a) value for each isomer was 6.8. Eel acetylcholinesterase inhibition studies were carried out at 25.0-degrees-C over the pH range of 6.0 to 9.0. They reflect the first pH profiles using enantiomorphs of a cholinesterase inhibitor. The inhibition potencies for (II) and (III) over the range examined were similar. At pH 7.60 the k(i) for II = 7.38 x 10(3) M-1 min-1 (SD = 398) and for (III) the k(i) = 6.67 x 10(3) M-1 min-1 (SD = 355). In accord with the findings of Wilson and Bergmann20 on physostigmine our results indicate that the protonated form of (II) and (III) is the more potent inhibitor. C1 ASH STEVENS INC,DETROIT,MI 48202. RP LIESKE, CN (reprint author), USA,MED RES INST CHEM DEF,ABERDEEN PROVING GROUND,MD 21010, USA. NR 34 TC 2 Z9 2 U1 1 U2 1 PU HARWOOD ACAD PUBL GMBH PI READING PA C/O STBS LTD, PO BOX 90, READING, BERKS, ENGLAND RG1 8JL SN 8755-5093 J9 J ENZYM INHIB JI J. Enzym. Inhib. PY 1993 VL 6 IS 4 BP 283 EP 291 DI 10.3109/14756369309020178 PG 9 WC Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA KY825 UT WOS:A1993KY82500003 ER PT J AU MOORE, DW DILLON, TM AF MOORE, DW DILLON, TM TI THE RELATIONSHIP BETWEEN GROWTH AND REPRODUCTION IN THE MARINE POLYCHAETE NEREIS(NEANTHES) ARENACEODENTATA (MOORE) - IMPLICATIONS FOR CHRONIC SUBLETHAL SEDIMENT BIOASSAYS SO JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY LA English DT Article DE BIOASSAY; GROWTH; NEANTHES; REPRODUCTION; SUBLETHAL ID LIFE-HISTORY TRAITS; NEANTHES-ARENACEODENTATA; CADMIUM; HORMESIS; NEREIDAE; RECOVERY; DENSITY AB The polychaete worm, Nereis (Neanthes) arenaceodentata (Moore), has historically been used to evaluate the acute lethality of sediments. More recently, a longer term (28-day) sediment bioassay has been proposed for this species in which the sublethal endpoint, growth, is also examined. However, interpretive guidance for the growth endpoint is lacking. To provide that guidance the quantitative relationship between diminutions in growth and subsequent reproduction was determined. Juvenile N. arenaceodentata were exposed to five geometrically decreasing food rations. Growth, as individual worm wet weight, was measured after 3, 6 and 9 wk. Worm growth increased significantly with increasing food ration. Eggs were first observed in the coelom of female worms at the 6-wk interval. Subsequent reproduction, measured as fecundity and number of juveniles produced, closely mirrored the reduced growth rates. No significant effect on either survival or reproduction was observed when somatic growth rate (measured between 0 to 6 wk) was greater than or equal to 0.65 mg/day. Growth rates less than or equal to 0.45 mg/day resulted in significant reductions in reproduction. Low growth rates (0.05 mg/day) were associated with a nearly complete cessation of reproduction and very poor survival (5-11%). The importance of distinguishing somatic growth from gametic growth in chronic sublethal sediment bioassays with N. arenaceodentata is discussed. RP MOORE, DW (reprint author), USAE,WATERWAYS EXPT STN,ENVIRONM LAB,3909 HALLS FERRY RD,VICKSBURG,MS 39180, USA. NR 34 TC 29 Z9 29 U1 1 U2 2 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0022-0981 J9 J EXP MAR BIOL ECOL JI J. Exp. Mar. Biol. Ecol. PY 1993 VL 173 IS 2 BP 231 EP 246 DI 10.1016/0022-0981(93)90055-S PG 16 WC Ecology; Marine & Freshwater Biology SC Environmental Sciences & Ecology; Marine & Freshwater Biology GA MK820 UT WOS:A1993MK82000005 ER PT J AU ROSSMAN, DI MULLER, AJ AF ROSSMAN, DI MULLER, AJ TI EXCHANGE-REACTIONS OF ORGANOTIN AND ORGANOSILICON COMPOUNDS WITH VINYLIC FLUORINE SO JOURNAL OF FLUORINE CHEMISTRY LA English DT Article AB Compounds carrying reactive fluorine atoms, such as methylphosphonic difluoride and perfluoroisobutene, undergo facile exchange with organosilanes and stannanes. Reactions with protic nucleophiles also yield similar products. To account for the products formed and observed reactivity differences, appropriate mechanisms are proposed. The reactions described herein have considerable synthetic utility. RP ROSSMAN, DI (reprint author), USA,CTR CHEM RES DEV & ENGN,ABERDEEN PROVING GROUND,MD 21010, USA. NR 6 TC 1 Z9 1 U1 1 U2 1 PU ELSEVIER SCIENCE SA LAUSANNE PI LAUSANNE 1 PA PO BOX 564, 1001 LAUSANNE 1, SWITZERLAND SN 0022-1139 J9 J FLUORINE CHEM JI J. Fluor. Chem. PD JAN PY 1993 VL 60 IS 1 BP 61 EP 68 DI 10.1016/S0022-1139(00)82196-X PG 8 WC Chemistry, Inorganic & Nuclear; Chemistry, Organic SC Chemistry GA KJ272 UT WOS:A1993KJ27200010 ER PT J AU MUNAVALLI, S ROSSMAN, DI ROHRBAUGH, DK FERGUSON, CP BANKS, HD AF MUNAVALLI, S ROSSMAN, DI ROHRBAUGH, DK FERGUSON, CP BANKS, HD TI SINGLE ELECTRON-TRANSFER CATALYZED SIMULTANEOUS CLEAVAGE OF C-S AND S-S BONDS SO JOURNAL OF FLUORINE CHEMISTRY LA English DT Article ID VOLATILE FLAVOR COMPONENTS; RADICALS; ALKYL; THERMOCHEMISTRY; ENZYMES; SPECTRA AB Since the S-S bond of polysulfides plays a vital role in biological processes, the chemistry of the S-S bond has attracted considerable attention. The reaction of bis-(trifluoromethyl) trisulfide with organolithium reagents at -78-degrees-C has now been found to cause simultaneous scissions of the C-S and S-S bonds and to furnish mixed monosulfides, disulfides and trisulfides containing the trifluoromethyl moiety. The formation of the various products has been rationalized on the basis of the involvement of the single electron transfer process. C1 USA,CTR CHEM RES DEV & ENGN,ABERDEEN PROVING GROUND,MD 21010. RP MUNAVALLI, S (reprint author), GEOCENTERS INC,FT WASHINGTON,MD 20744, USA. NR 61 TC 18 Z9 18 U1 1 U2 3 PU ELSEVIER SCIENCE SA LAUSANNE PI LAUSANNE 1 PA PO BOX 564, 1001 LAUSANNE 1, SWITZERLAND SN 0022-1139 J9 J FLUORINE CHEM JI J. Fluor. Chem. PD JAN PY 1993 VL 60 IS 1 BP 85 EP 91 DI 10.1016/S0022-1139(00)82199-5 PG 7 WC Chemistry, Inorganic & Nuclear; Chemistry, Organic SC Chemistry GA KJ272 UT WOS:A1993KJ27200013 ER PT J AU MANN, RW AF MANN, RW TI A METHOD FOR SIDING AND SEQUENCING HUMAN RIBS SO JOURNAL OF FORENSIC SCIENCES LA English DT Note DE PHYSICAL ANTHROPOLOGY; HUMAN RIB; OSTEOLOGY; FORENSIC ANTHROPOLOGY AB Siding and sequencing (that is putting in anatomical order) human ribs are essential to the proper examination and documentation of injuries to the chest. The paucity of information regarding sequencing nonfleshed human ribs makes it particularly difficult for physical anthropologists and medicolegal authorities to differentiate the midthoracic ribs. It was found that ribs could be accurately sequenced without the aid of a comparative skeleton using such features as maximum (relative) rib length. the size and shape of the articular facets, the distance between the articular facets and rib angle. and the height of the rib heads relative to one another. RP MANN, RW (reprint author), USA,CENT ID LAB,BLDG 45,FT KAMEHAMEHA,HICKAM AFB,HI 96853, USA. NR 6 TC 19 Z9 19 U1 0 U2 2 PU AMER SOC TESTING MATERIALS PI W CONSHOHOCKEN PA 100 BARR HARBOR DR, W CONSHOHOCKEN, PA 19428-2959 SN 0022-1198 J9 J FORENSIC SCI JI J. Forensic Sci. PD JAN PY 1993 VL 38 IS 1 BP 151 EP 155 PG 5 WC Medicine, Legal SC Legal Medicine GA KH541 UT WOS:A1993KH54100024 PM 8426150 ER PT J AU FERRICK, MG CLAFFEY, KJ AF FERRICK, MG CLAFFEY, KJ TI VECTOR ANALYSIS OF ICE-FABRIC DATA SO JOURNAL OF GLACIOLOGY LA English DT Article AB The mechanical properties of ice are strongly affected by crystal texture and c-axis alignment. In this paper, we develop a general quantitative method for analysis of uniaxial crystal-orientation data. These data are represented as unit vectors from the origin with end points on the surface of a unit sphere. An orthogonal least-squares error measure is used to develop equations that define the closest plane and line through the data. The resulting eigenvalue problem is identical to that obtained by other investigators using different methods. However, here we identify an implicit assumption in the method, and observe that the error measure represents physical distance and quantifies the goodness of fit to the data of idealized structures. Also, a method is developed to transform the data and the results for viewing on Schmidt nets drawn in the best plane and the predominant basal plane of a sample, in addition to the standard xy-plane. Applications of the analysis to sea-ice samples include both numerical and Schmidt-net presentations of results. RP FERRICK, MG (reprint author), USA,COLD REG RES & ENGN LAB,HANOVER,NH 03755, USA. NR 19 TC 2 Z9 2 U1 0 U2 1 PU INT GLACIOL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE, ENGLAND CB2 1ER SN 0022-1430 J9 J GLACIOL JI J. Glaciol. PY 1993 VL 39 IS 132 BP 292 EP 302 PG 11 WC Geography, Physical; Geosciences, Multidisciplinary SC Physical Geography; Geology GA MK676 UT WOS:A1993MK67600010 ER PT J AU RICHTERMENGE, JA JONES, KF AF RICHTERMENGE, JA JONES, KF TI THE TENSILE-STRENGTH OF 1ST-YEAR SEA-ICE SO JOURNAL OF GLACIOLOGY LA English DT Article ID SALINITY; SAMPLES AB We present the results of tests done to determine the tensile behavior of first-year columnar sea ice over a range of temperatures from -20-degrees to -3-degrees-C and strain rates of 10(-5) and 10(-3) s-1. The temperature of a test specimen was dictated by its in-situ location within the sea-ice sheet; samples located near the top of the sea-ice sheet were tested at the lower temperatures. A tensile load was applied along the cylindrical axes of the test specimens, which were perpendicular to the growth direction of the ice. Results showed that the maximum stress reached during a test was most strongly influenced by temperature, while the failure strain and the modulus were principally affected by the loading rate. A model relating the tensile strength of the ice to its porosity based on temperature-dependent variations in the brine-pocket geometry is evaluated. RP RICHTERMENGE, JA (reprint author), USA,COLD REG RES & ENGN LAB,HANOVER,NH 03755, USA. NR 30 TC 35 Z9 35 U1 0 U2 5 PU INT GLACIOL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE, ENGLAND CB2 1ER SN 0022-1430 J9 J GLACIOL JI J. Glaciol. PY 1993 VL 39 IS 133 BP 609 EP 618 PG 10 WC Geography, Physical; Geosciences, Multidisciplinary SC Physical Geography; Geology GA NA692 UT WOS:A1993NA69200019 ER PT J AU RICHTERMENGE, JA CLAFFEY, KJ WALSH, MR AF RICHTERMENGE, JA CLAFFEY, KJ WALSH, MR TI END-CAPPING PROCEDURE FOR CORED ICE SAMPLES USED IN TENSION TESTS SO JOURNAL OF GLACIOLOGY LA English DT Article AB This note describes an end-capping procedure used to prepare cylindrical ice-core samples for direct tension testing. The techniques developed build on work done by Cole and others (1985) and Lee (1986), and include a design modification to the loading train and a more reliable approach to establishing the fresh-water bond used to mount the end caps on the sample. Using these techniques, an 88% success rate was achieved in a recent series of uniaxial tension tests. RP RICHTERMENGE, JA (reprint author), USA,COLD REG RES & ENGN LAB,HANOVER,NH 03755, USA. NR 13 TC 4 Z9 4 U1 0 U2 0 PU INT GLACIOL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE, ENGLAND CB2 1ER SN 0022-1430 J9 J GLACIOL JI J. Glaciol. PY 1993 VL 39 IS 133 BP 698 EP 700 PG 3 WC Geography, Physical; Geosciences, Multidisciplinary SC Physical Geography; Geology GA NA692 UT WOS:A1993NA69200028 ER PT J AU KOVACS, A AF KOVACS, A TI DYEING OF SNOW SURFACES TO OBSERVE SNOW STRUCTURE SO JOURNAL OF GLACIOLOGY LA English DT Letter RP KOVACS, A (reprint author), USA,COLD REG RES & ENGN LAB,HANOVER,NH 03755, USA. NR 4 TC 1 Z9 1 U1 0 U2 0 PU INT GLACIOL SOC PI CAMBRIDGE PA LENSFIELD RD, CAMBRIDGE, ENGLAND CB2 1ER SN 0022-1430 J9 J GLACIOL JI J. Glaciol. PY 1993 VL 39 IS 133 BP 709 EP 711 PG 3 WC Geography, Physical; Geosciences, Multidisciplinary SC Physical Geography; Geology GA NA692 UT WOS:A1993NA69200033 ER PT J AU HESS, RA MALSBURY, T ATENCIO, A AF HESS, RA MALSBURY, T ATENCIO, A TI FLIGHT SIMULATOR FIDELITY ASSESSMENT IN A ROTORCRAFT LATERAL TRANSLATION MANEUVER SO JOURNAL OF GUIDANCE CONTROL AND DYNAMICS LA English DT Article ID MODEL AB A model-based methodology for assessing flight simulator fidelity in closed-loop fashion is exercised in analyzing a rotorcraft low-altitude maneuver for which flight test and simulation results were available. The addition of a handling qualities sensitivity function to a previously developed model-based assessment criteria allows an analytical comparison of both performance and handling qualities between simulation and flight test. Model predictions regarding the existence of simulator fidelity problems are corroborated by experiment. The modeling approach is used to assess analytically the effects of modifying simulator characteristics on simulator fidelity. C1 USA,AEROFLIGHTDYNAM DIRECTORATE,NASA,AMES RES CTR,MOFFETT FIELD,CA 94035. RP HESS, RA (reprint author), UNIV CALIF DAVIS,DEPT MECH AERONAUT & MAT ENGN,DAVIS,CA 95616, USA. NR 14 TC 10 Z9 10 U1 0 U2 0 PU AMER INST AERONAUT ASTRONAUT PI RESTON PA 1801 ALEXANDER BELL DRIVE, STE 500, RESTON, VA 22091 SN 0731-5090 J9 J GUID CONTROL DYNAM JI J. Guid. Control Dyn. PD JAN-FEB PY 1993 VL 16 IS 1 BP 79 EP 85 DI 10.2514/3.11430 PG 7 WC Engineering, Aerospace; Instruments & Instrumentation SC Engineering; Instruments & Instrumentation GA KJ330 UT WOS:A1993KJ33000012 ER PT J AU JOHNSON, BH KIM, KW HEATH, RE HSIEH, BB BUTLER, HL AF JOHNSON, BH KIM, KW HEATH, RE HSIEH, BB BUTLER, HL TI VALIDATION OF 3-DIMENSIONAL HYDRODYNAMIC MODEL OF CHESAPEAKE BAY SO JOURNAL OF HYDRAULIC ENGINEERING-ASCE LA English DT Article AB A time-varying three-dimensional numerical hydrodynamic model of Chesapeake Bay in Maryland has been developed to provide flow fields to a 3-D water quality model of the bay. The water surface, 3-D velocity field, salinity, and temperature are computed. Major physical processes affecting bay circulation and vertical mixing are modeled. A particular feature of the model is the solution of transformed equations on a boundary-fitted grid in the horizontal plane. The 3-D model has been validated through application to six data sets. The first three were about one month long each and represented a dry summer condition, a spring runoff, and a fall wind-mixing event. The last three applications were yearlong simulations for 1984, 1985, and 1986. These years represent a wet, dry, and average freshwater inflow year, respectively. A major storm in November 1985 over the lower portion of the bay resulted in a 200-year flood on the James River and served to demonstrate the ability of the model to simulate extreme events. Selected results from application to the fall 1983 data and from the yearlong simulations are presented here. These results demonstrate that the model is a good representation of the hydrodynamics of the Chesapeake Bay and its major tributaries. C1 USA,ENGR WTRWY EXPT STN,COAST ENGRG RES CTR,VICKSBURG,MS 39180. RP JOHNSON, BH (reprint author), USA,ENGR WTRWY EXPT STN,HYDR LAB,3909 HALLS FERRY RD,VICKSBURG,MS 39180, USA. NR 13 TC 64 Z9 64 U1 1 U2 6 PU ASCE-AMER SOC CIVIL ENGINEERS PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017-2398 SN 0733-9429 J9 J HYDRAUL ENG-ASCE JI J. Hydraul. Eng.-ASCE PD JAN PY 1993 VL 119 IS 1 BP 2 EP 20 DI 10.1061/(ASCE)0733-9429(1993)119:1(2) PG 19 WC Engineering, Civil; Engineering, Mechanical; Water Resources SC Engineering; Water Resources GA KE668 UT WOS:A1993KE66800001 ER PT J AU COUTERMARSH, BA MCGILVARY, WR AF COUTERMARSH, BA MCGILVARY, WR TI STATIC ANALYSIS OF FLOATING ICE BLOCK STABILITY SO JOURNAL OF HYDRAULIC RESEARCH LA English DT Article AB A laboratory study was performed to measure the pressures caused by fluid acceleration beneath a floating parallel-piped block. Dynamic fluid pressure was measured at discrete points beneath the block for various fluid velocities, block angles of attack and block thickness-to-depth ratios. Some of these pressures tended to stabilize the block while others tended to underturn it. The measured pressures were used to calculate block underturning moments and a hydrostatic analysis was used to calculate a block righting moment. From this, a densimetric Froude underturning criteria is presented. RP COUTERMARSH, BA (reprint author), USA,COLD REG RES & ENGN LAB,HANOVER,NH 03755, USA. NR 7 TC 2 Z9 2 U1 0 U2 0 PU INT ASSN HYDRAULIC RESEARCH PI DELFT PA PO BOX 177, 2600 DELFT, NETHERLANDS SN 0022-1686 J9 J HYDRAUL RES JI J. Hydraul. Res. PY 1993 VL 31 IS 2 BP 147 EP 160 PG 14 WC Engineering, Civil; Water Resources SC Engineering; Water Resources GA LB636 UT WOS:A1993LB63600001 ER PT J AU KRAKAUER, T AF KRAKAUER, T TI A SENSITIVE, SPECIFIC IMMUNOBIOASSAY FOR QUANTITATION OF HUMAN INTERLEUKIN-6 SO JOURNAL OF IMMUNOASSAY LA English DT Article DE IMMUNOBIOASSAY; HUMAN INTERLEUKIN-6; IL-6 ID INFECTION; SERUM; IL-6 AB Picogram quantities of human interleukin 6 (h-IL-6) were detected by a two-step method. A microtiter plate coated with anti-h IL-6 monoclonal antibody was used to capture the IL-6 present in biological samples. An IL-6- dependent B cell line (7TD1) that proliferates in response to IL-6 was added to the captured IL-6. The lower limit of detection for this immunobioassay with serum or cell culture supernatants was 5 pg/ml. The specificity of the assay was achieved by the antibody used in the first step. The sensitivity was provided by the IL-6-dependent cell line. The method also allows for the removal of inhibitors, metabolites, antagonists or activating agents used to induce IL-6. This immunobioassay has the advantage over other current methods in that it measures immunoactive as well as biologically active IL-6. RP KRAKAUER, T (reprint author), USA,MED RES INST INFECT DIS,DIV APPL RES,FREDERICK,MD 21702, USA. NR 10 TC 24 Z9 24 U1 0 U2 0 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0197-1522 J9 J IMMUNOASSAY JI J. Immunoass. PY 1993 VL 14 IS 4 BP 267 EP 277 DI 10.1080/15321819308019854 PG 11 WC Biochemistry & Molecular Biology; Immunology; Medical Laboratory Technology SC Biochemistry & Molecular Biology; Immunology; Medical Laboratory Technology GA ME681 UT WOS:A1993ME68100004 PM 7905011 ER PT J AU CROSS, AS OPAL, SM PALARDY, JE BODMER, MW SADOFF, JC AF CROSS, AS OPAL, SM PALARDY, JE BODMER, MW SADOFF, JC TI THE EFFICACY OF COMBINATION IMMUNOTHERAPY IN EXPERIMENTAL PSEUDOMONAS SEPSIS SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID TUMOR-NECROSIS-FACTOR; GRAM-NEGATIVE BACTEREMIA; SEPTIC SHOCK; MONOCLONAL-ANTIBODIES; FACTOR-ALPHA; LIPOPOLYSACCHARIDE LPS; PASSIVE-IMMUNIZATION; LETHAL BACTEREMIA; ESCHERICHIA-COLI; PROTECTS MICE AB Immunotherapy has been shown to be an effective adjuvant in the management of septic shock. A neutropenic rat model of septic shock induced by infection with Pseudomonas aeruginosa 12.4.4 (Fisher immunotype 6) was used to determine the relative efficacy of single, double, and triple combination immunotherapy. A Pseudomonas O serotype-specific, opsonophagocytic monoclonal antibody (MAb), polyclonal J5 antiserum, and a MAb directed against tumor necrosis factor-alpha (TNF) were studied as single therapy and in combination. The combination of all three immunotherapeutic agents resulted in a 77% survival rate (33/43 animals). This level of protection was superior to that achieved with any combination of two antibody treatments (50%-60% survival; P = .029) or single antibody therapy (25%-43% survival; P < .001) or compared with a control group (0/25 survivors; P < .0001). Immunotherapy directed against multiple steps of the septic process is more active than single or double antibody regimens and may offer an improved approach to the adjunctive treatment of septic shock. C1 BROWN UNIV,SCH MED,DIV INFECT DIS,PROVIDENCE,RI 02912. CELLTECH LTD,SLOUGH,ENGLAND. RP CROSS, AS (reprint author), WALTER REED ARMY INST RES,DEPT BACTERIAL DIS,WASHINGTON,DC 20307, USA. NR 37 TC 46 Z9 46 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD JAN PY 1993 VL 167 IS 1 BP 112 EP 118 PG 7 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA KE846 UT WOS:A1993KE84600017 PM 8418157 ER PT J AU HAQUE, R KRESS, K WOOD, S JACKSON, TFHG LYERLY, D WILKINS, T PETRI, WA AF HAQUE, R KRESS, K WOOD, S JACKSON, TFHG LYERLY, D WILKINS, T PETRI, WA TI DIAGNOSIS OF PATHOGENIC ENTAMOEBA-HISTOLYTICA INFECTION USING A STOOL ELISA BASED ON MONOCLONAL-ANTIBODIES TO THE GALACTOSE-SPECIFIC ADHESIN SO JOURNAL OF INFECTIOUS DISEASES LA English DT Note ID ISOENZYME PATTERNS; SURFACE-ANTIGEN AB Monoclonal antibodies (MAbs) directed against pathogen-specific epitopes of the galactose adhesin of Entamoeba histolytica were used in an ELISA to detect antigen from pathogenic E. histolytica. Single stool specimens from 74 patients in Bangladesh were used. The ELISA for pathogenic E. histolytica was positive in all 12 stool specimens with pathogenic amebae subsequently cultured, in no stool specimens with nonpathogenic E. histolytica and in 2 of 40 stools with other or no intestinal parasites detected. Specificity and sensitivity of the assay for pathogenic E. histolytica were 97% and 100%, respectively. These preliminary data offer promise for an ELISA using MAbs to the galactose adhesin as a rapid and sensitive means to detect the presence of pathogenic E. histolytica infection in stool specimens. C1 INT CTR DIARRHOEAL DIS RES,DHAKA,BANGLADESH. USA,CHEM RES DEV COMMAND,ABERDEEN PROVING GROUND,MD 21010. RES INST DIS TROP ENVIRONM,CONGELLA,SOUTH AFRICA. UNIV VIRGINIA,TECH LAB,CHARLOTTESVILLE,VA 22903. UNIV VIRGINIA,DEPT MED,CHARLOTTESVILLE,VA 22903. UNIV VIRGINIA,DEPT MICROBIOL,CHARLOTTESVILLE,VA 22903. FU NIAID NIH HHS [AI-26649] NR 13 TC 68 Z9 74 U1 0 U2 1 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD JAN PY 1993 VL 167 IS 1 BP 247 EP 249 PG 3 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA KE846 UT WOS:A1993KE84600043 PM 8369019 ER PT J AU SCHULZ, DE AF SCHULZ, DE TI CAN CASTRO SURVIVE SO JOURNAL OF INTERAMERICAN STUDIES AND WORLD AFFAIRS LA English DT Article RP SCHULZ, DE (reprint author), USA,WAR COLL,INST STRATEG STUDIES,CARLISLE,PA 17013, USA. NR 11 TC 4 Z9 4 U1 0 U2 0 PU UNIV MIAMI PI CORAL GABLES PA J INTERAMER STUD WORLD AFF PO BOX 248134, CORAL GABLES, FL 33124 SN 0022-1937 J9 J INTERAM STUD WORLD JI J. Interam. Stud. World Aff. PY 1993 VL 35 IS 1 BP 89 EP 117 DI 10.2307/166103 PG 29 WC Area Studies; International Relations; Political Science SC Area Studies; International Relations; Government & Law GA LM742 UT WOS:A1993LM74200003 ER PT J AU NARAYANAN, RB DRABICK, JJ WILLIAMS, JC FORTIER, AH MELTZER, MS SADOFF, JC BOLT, CR NACY, CA AF NARAYANAN, RB DRABICK, JJ WILLIAMS, JC FORTIER, AH MELTZER, MS SADOFF, JC BOLT, CR NACY, CA TI IMMUNOTHERAPY OF TULAREMIA - CHARACTERIZATION OF A MONOCLONAL-ANTIBODY REACTIVE WITH FRANCISELLA-TULARENSIS SO JOURNAL OF LEUKOCYTE BIOLOGY LA English DT Note DE ANTIBODIES; FRANCISELLA-TULARENSIS; LIVE VACCINE STRAIN; LIPOPOLYSACCHARIDE; IMMUNOFLUORESCENCE ASSAY; ELISA ID GAMMA-INTERFERON; PROTEINS; LIPOPOLYSACCHARIDE; RESISTANCE; INFECTION; ENDOTOXIN; IMMUNITY; MODEL; MICE AB An IgM monoclonal antibody (mAb) recognized surface antigens specific to Francisella tularensis wild-type (Schu4) and live vaccine strain (LVS), and reacted with both in ELISA and slide agglutination tests. This mAb also reacted with LVS microorganisms in tissues of infected mice as assessed by an indirect fluorescence technique. Western blot analysis showed the mAb to react with antigens associated with F. tularensis LPS. C1 WALTER REED ARMY INST RES,DEPT CELLULAR IMMUNOL,9620 MED CTR DR 200,ROCKVILLE,MD 20850. WALTER REED ARMY INST RES,DEPT BACTERIAL DIS,WASHINGTON,DC 20307. USA,INST INFECT DIS,DIV BACTERIOL,INTRACELLULAR PATHOGENS BRANCH,FREDERICK,MD 21701. NR 40 TC 12 Z9 14 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0741-5400 J9 J LEUKOCYTE BIOL JI J. Leukoc. Biol. PD JAN PY 1993 VL 53 IS 1 BP 112 EP 116 PG 5 WC Cell Biology; Hematology; Immunology SC Cell Biology; Hematology; Immunology GA KK631 UT WOS:A1993KK63100016 PM 8426087 ER PT J AU MELTZER, MS FAN, SX ARONOVITZ, JR TURPIN, JA AF MELTZER, MS FAN, SX ARONOVITZ, JR TURPIN, JA TI ANTIVIRAL ACTIONS OF INTERFERONS (IFN) ALPHA AND GAMMA AGAINST HUMAN IMMUNODEFICIENCY VIRUS-TYPE-1 (HIV) INFECTION OF MONOCYTES SO JOURNAL OF LEUKOCYTE BIOLOGY LA English DT Meeting Abstract C1 WALTER REED ARMY INST RES,DEPT CELL IMMUNOL,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0741-5400 J9 J LEUKOCYTE BIOL JI J. Leukoc. Biol. PY 1993 SU S BP 73 EP 73 PG 1 WC Cell Biology; Hematology; Immunology SC Cell Biology; Hematology; Immunology GA ME185 UT WOS:A1993ME18500237 ER PT J AU DHAWAN, S HEWLETT, I UHING, R WHITE, J WONG, H CIANCIOLO, G ARONOVITZ, J MELTZER, M AF DHAWAN, S HEWLETT, I UHING, R WHITE, J WONG, H CIANCIOLO, G ARONOVITZ, J MELTZER, M TI SYNTHETIC PEPTIDE DERIVED FROM HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV) GP41 INHIBITS HIV-INFECTION OF MONOCYTES SO JOURNAL OF LEUKOCYTE BIOLOGY LA English DT Meeting Abstract C1 US FDA,DIV TRANSFUS TRANSMITTED DIS,MOLEC VIROL LAB,ROCKVILLE,MD 20895. MACRONEX INC,MORRISVILLE,NC 27560. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0741-5400 J9 J LEUKOCYTE BIOL JI J. Leukoc. Biol. PY 1993 SU S BP 74 EP 74 PG 1 WC Cell Biology; Hematology; Immunology SC Cell Biology; Hematology; Immunology GA ME185 UT WOS:A1993ME18500241 ER PT J AU BURLESON, DG WOLCOTT, KM MASON, AD PRUITT, BA AF BURLESON, DG WOLCOTT, KM MASON, AD PRUITT, BA TI DIFFERENTIAL SURFACE-MOLECULE EXPRESSION AFTER BURN INJURY SO JOURNAL OF LEUKOCYTE BIOLOGY LA English DT Meeting Abstract C1 USA,INST SURG RES,FT SAM HOUSTON,TX 78234. NR 0 TC 0 Z9 0 U1 0 U2 0 PU FEDERATION AMER SOC EXP BIOL PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 SN 0741-5400 J9 J LEUKOCYTE BIOL JI J. Leukoc. Biol. PY 1993 SU S BP 127 EP 127 PG 1 WC Cell Biology; Hematology; Immunology SC Cell Biology; Hematology; Immunology GA ME185 UT WOS:A1993ME18500559 ER PT J AU IDOWU, OR ADEWUYI, GO AF IDOWU, OR ADEWUYI, GO TI SODIUM BENZOXAZOLE-2-SULFONATE - A DERIVATIZATION REAGENT FOR THE ANALYSIS OF AMINES AND AMINO-ACIDS BY HPLC WITH FLUORESCENCE OR UV DETECTION SO JOURNAL OF LIQUID CHROMATOGRAPHY LA English DT Article ID PRESSURE LIQUID-CHROMATOGRAPHY; ELECTRON-CAPTURE DETECTION; GAS-CHROMATOGRAPHY; THIN-LAYER; DERIVATIZATION; DERIVATIVES; POLYAMINES; SEPARATION; TISSUES AB The preparation of sodium benzoxazole-2-sulfonate and its use as a reagent for the formation of fluorescent derivatives of amines and amino acids is described. Sodium benzoxazole-2-sulfonate is readily prepared by boiling 2-chlorobenzoxazole with sodium sulfite. Sodium benzoxazole-2-sulfonate is non-fluorescent, but reacts with amines and amino acids to give derivatives which exhibit intense blue fluorescence. The solubility of the compound in water also makes it particularly advantageous as a reagent for the derivatisation of amino acids. Furthermore, sodium benzoxazole-2-sulfonate may be tagged onto an ion-exchange resin, in which form it may be used for heterogeneous on-line pre- or post-column derivatisation of amines and amino acids. C1 UNIV IBADAN,DEPT CHEM,IBADAN,NIGERIA. RP IDOWU, OR (reprint author), WALTER REED ARMY INST RES,DEPT PHARMACOL,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307, USA. NR 25 TC 7 Z9 7 U1 0 U2 4 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0148-3919 J9 J LIQ CHROMATOGR JI J. Liq. Chromatogr. PY 1993 VL 16 IS 12 BP 2501 EP 2518 DI 10.1080/10826079308019588 PG 18 WC Biochemical Research Methods; Chemistry, Analytical SC Biochemistry & Molecular Biology; Chemistry GA LN477 UT WOS:A1993LN47700005 ER PT J AU IDOWU, OR ADEWUYI, GO AF IDOWU, OR ADEWUYI, GO TI SODIUM BENZOXAZOLE-2-SULFONATE - A DERIVATIZATION REAGENT FOR THE ANALYSIS OF AMINES AND AMINO-ACIDS BY HPLC WITH FLUORESCENCE OR UV DETECTION SO JOURNAL OF LIQUID CHROMATOGRAPHY LA English DT Article ID PRESSURE LIQUID-CHROMATOGRAPHY; ELECTRON-CAPTURE DETECTION; GAS-CHROMATOGRAPHY; THIN-LAYER; DERIVATIZATION; DERIVATIVES; POLYAMINES; SEPARATION; TISSUES AB The preparation of sodium benzoxazole-2-sulfonate and its use as a reagent for the formation of fluorescent derivatives of amines and amino acids is described. Sodium benzoxazole-2-sulfonate is readily prepared by boiling 2-chlorobenzoxazole with sodium sulfite. Sodium benzoxazole-2-sulfonate is non-fluorescent, but reacts with-amines and amino acids to give derivatives which exhibit intense blue C1 UNIV IBADAN,DEPT CHEM,IBADAN,NIGERIA. RP IDOWU, OR (reprint author), WALTER REED ARMY INST RES,DEPT PHARMACOL,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307, USA. NR 25 TC 2 Z9 2 U1 0 U2 0 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0148-3919 J9 J LIQ CHROMATOGR JI J. Liq. Chromatogr. PY 1993 VL 16 IS 17 BP 3773 EP 3791 DI 10.1080/10826079308019666 PG 19 WC Biochemical Research Methods; Chemistry, Analytical SC Biochemistry & Molecular Biology; Chemistry GA MK145 UT WOS:A1993MK14500012 ER PT J AU KAMATH, M LIM, JO CHITTIBABU, KG SARMA, R KUMAR, J MARX, KA TRIPATHY, SK AF KAMATH, M LIM, JO CHITTIBABU, KG SARMA, R KUMAR, J MARX, KA TRIPATHY, SK TI BIOTINYLATED POLY(3-HEXYLTHIOPHENE-CO-3-METHANOLTHIOPHENE) - A LANGMUIR MONOLAYER-FORMING COPOLYMER SO JOURNAL OF MACROMOLECULAR SCIENCE-PURE AND APPLIED CHEMISTRY LA English DT Article ID POLYMERIZED 3-METHOXYTHIOPHENE; CONDUCTING POLYMERS; POLYTHIOPHENE; POLYPYRROLE AB Copolymers of 3-substituted thiophenes have been synthesized by organosynthetic routes. The chemical synthesis of the copolymer was carried out by dehydrogenation of 3-hexylthiophene and 3-methanolthiophene. Attachment of biotin to the resulting copolymer, poly(3-hexylthiophene-co-3-methanolthiophene) [PMHT], is accomplished by room temperature esterification using N,N-dicyclohexylcarbodiimide (DCC) and 4-pyrrolidinopyridine as catalyst. The resulting copolymers have well-defined chemical and electronic structures and molecular weights. The biotinylated copolymer forms a stable monolayer at the air-water interface due to the polar groups along the polymer backbone. C1 UNIV MASSACHUSETTS LOWELL,DEPT PHYS,LOWELL,MA 01854. USA,NATICK RES,DIV BIOTECHNOL,CTR DEV & ENGN,NATICK,MA 01760. RP KAMATH, M (reprint author), UNIV MASSACHUSETTS LOWELL,DEPT CHEM,CTR ADV MAT,LOWELL,MA 01854, USA. NR 34 TC 8 Z9 8 U1 0 U2 1 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 1060-1325 J9 J MACROMOL SCI PURE JI J. Macromol. Sci.-Pure Appl. Chem. PY 1993 VL A30 IS 8 BP 493 EP 502 DI 10.1080/10601329308009425 PG 10 WC Polymer Science SC Polymer Science GA LP569 UT WOS:A1993LP56900001 ER PT J AU DURDEN, LA LINTHICUM, KJ MONATH, TP AF DURDEN, LA LINTHICUM, KJ MONATH, TP TI LABORATORY TRANSMISSION OF EASTERN EQUINE ENCEPHALOMYELITIS VIRUS TO CHICKENS BY CHICKEN MITES (ACARI, DERMANYSSIDAE) SO JOURNAL OF MEDICAL ENTOMOLOGY LA English DT Note DE DERMANYSSUS-GALLINAE; VECTOR COMPETENCE; EASTERN EQUINE ENCEPHALOMYELITIS VIRUS AB Pools of adult female chicken mites, Dermanyssus gallinae (De Geer), were allowed to feed on chicks that had been inoculated with eastern equine encephalomyelitis (EEE) virus and that had a viremia level of 10(6.2)-10(6.6) plaque-forming units per milliliter of blood. Virus remained detectable by plaque assay in samples of these mites for 30 d after the infectious blood meal. Virus was not recovered from any of 151 progeny of virus-exposed female mites. Mites that had fed on viremic chicks were allowed to feed on naive chicks 3, 7, 11, 15, or 30 d later. EEE virus was transmitted to chicks by these mites on days 3 (one transmission in four trials) and 7 (one transmission in four trials). Both transmissions were confirmed by the presence of virus in chick blood 24-72 h after mites had fed, and by plaque-reduction neutralization assays of 21-d convalescent chick sera against the original viral strain. C1 USA,MED RES INST INFECT DIS,DIV VIROL,FREDERICK,MD 21702. NR 13 TC 29 Z9 30 U1 0 U2 5 PU ENTOMOL SOC AMER PI LANHAM PA 9301 ANNAPOLIS RD, LANHAM, MD 20706 SN 0022-2585 J9 J MED ENTOMOL JI J. Med. Entomol. PD JAN PY 1993 VL 30 IS 1 BP 281 EP 285 PG 5 WC Entomology; Veterinary Sciences SC Entomology; Veterinary Sciences GA KJ315 UT WOS:A1993KJ31500038 PM 8433339 ER PT J AU DOHM, DJ LINTHICUM, KJ AF DOHM, DJ LINTHICUM, KJ TI EFFECTS OF TEMPERATURE ON FECUNDITY AND VIRAL REPLICATION IN AMBLYOMMA-CAJENNENSE (ARACHNIDA, IXODIDAE) INFECTED WITH VENEZUELAN EQUINE ENCEPHALOMYELITIS VIRUS SO JOURNAL OF MEDICAL ENTOMOLOGY LA English DT Note DE AMBLYOMMA-CAJENNENSE; TEMPERATURE; VENEZUELAN EQUINE ENCEPHALOMYELITIS ID VALLEY FEVER VIRUS; AEDES-TRISERIATUS DIPTERA; LA-CROSSE VIRUS; CULEX-PIPIENS; RHIPICEPHALUS-APPENDICULATUS; EXTRINSIC INCUBATION; HYALOMMA-TRUNCATUM; VECTOR COMPETENCE; TRANSMISSION; TICK AB To assess how temperature affects fecundity and Venezuelan equine encephalomyelitis (VEE) viral replication in VEE-infected Amblyomma cajennense (F.), adult ticks were inoculated intracoelomically with either VEE virus (I-A variant) or diluent. Ticks were held at 19, 26, or 33-degrees-C and tested for VEE virus over 20 d. Up to 10 pairs of ticks (1 female: 1 male) from each temperature group were allowed to feed on guinea pigs on day 8 after inoculation. Maximum titers did not differ significantly among infected ticks held at 19, 26, or 330-degrees-C (P = 0.59), and ticks maintained high viral titers throughout the sampling period. Likewise, there was no significant difference in the number of eggs oviposited between ticks inoculated with virus or diluent and held at the same temperature, or among groups held at different temperatures (P = 0.48). The percentage of viable eggs from virus-inoculated or diluent-inoculated adults also was not significantly different (P greater-than-or-equal-to 0.14). RP DOHM, DJ (reprint author), USA,MED RES INST INFECT DIS,DEPT EPIDEMIOL,DIV DIS ASSESSMENT,FREDERICK,MD 21702, USA. NR 26 TC 2 Z9 2 U1 0 U2 0 PU ENTOMOL SOC AMER PI LANHAM PA 9301 ANNAPOLIS RD, LANHAM, MD 20706 SN 0022-2585 J9 J MED ENTOMOL JI J. Med. Entomol. PD JAN PY 1993 VL 30 IS 1 BP 286 EP 290 PG 5 WC Entomology; Veterinary Sciences SC Entomology; Veterinary Sciences GA KJ315 UT WOS:A1993KJ31500039 PM 8433340 ER PT J AU CATTERLIN, RK PLUMMER, KD GULLEY, ME AF CATTERLIN, RK PLUMMER, KD GULLEY, ME TI EFFECT OF TINFOIL SUBSTITUTE CONTAMINATION ON ADHESION OF RESIN DENTURE TOOTH TO ITS DENTURE BASE SO JOURNAL OF PROSTHETIC DENTISTRY LA English DT Article ID RETENTION GROOVES; TEETH; BOND AB At least one manufacturer claims that contamination of denture teeth with tinfoil substitute during processing is not detrimental. The purpose of this study was to determine whether tinfoil substitute contamination has any significant eff ect on the bond strength between acrylic resin denture teeth and their processed acrylic resin base. Eighty acrylic resin maxillary central incisors were processed to denture base material. The experimental group had the denture tooth ridgelap area contaminated with tinfoil substitute. The control group was not contaminated. The bond strength of the two groups was tested. The results indicate that contamination with tinfoil substitute significantly reduces the bond strength of acrylic resin denture teeth bonded to their denture base. C1 USA,BILLY JOHNSON DENT CLIN,FT HOOD,TX 76544. USA,ADV EDUC PROGRAM GEN DENT,FT HOOD,TX 76544. NR 9 TC 19 Z9 19 U1 0 U2 1 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0022-3913 J9 J PROSTHET DENT JI J. Prosthet. Dent. PD JAN PY 1993 VL 69 IS 1 BP 57 EP 59 DI 10.1016/0022-3913(93)90241-F PG 3 WC Dentistry, Oral Surgery & Medicine SC Dentistry, Oral Surgery & Medicine GA KF761 UT WOS:A1993KF76100012 PM 8455169 ER PT J AU FABRY, DA LEEK, MR WALDEN, BE CORD, M AF FABRY, DA LEEK, MR WALDEN, BE CORD, M TI DO ADAPTIVE FREQUENCY-RESPONSE (AFR) HEARING-AIDS REDUCE UPWARD SPREAD OF MASKING SO JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT LA English DT Article DE ADAPTIVE FREQUENCY RESPONSE; HEARING AIDS; HIGH-PASS FILTERS; PURE-TONE MASKING PATTERNS; SPEECH RECOGNITION IN NOISE; UPWARD SPREAD OF MASKING ID ARTICULATION-INDEX; INTELLIGIBILITY; FILTER; NOISE AB Speech recognition scores in noise are improved for some subjects who wear hearing aids that reduce low-frequency noise with an adjustable high-pass filter circuit. To evaluate whether these improvements were related to a reduction in upward spread of masking, pure-tone masking patterns for a low-frequency bandpass noise were measured in normal and hearing-impaired subjects. The filter skirt of the noise masker was very steep, with attenuation above the 1000 Hz cutoff greater than 120 dB per octave. Masking patterns for the same noise were also obtained in the presence of a high-pass filter that simulated the effects of an adaptive frequency response (AFR) hearing aid. Differences in the masking patterns were considered a measure of upward spread of masking. On average, subjects with high-frequency hearing loss demonstrated greater amounts of upward spread of masking than did normal-hearing listeners. Further, monosyllabic speech recognition in noise testing indicated improvements in performance of the hearing-impaired subjects related to the decrease of upward spread of masking in the high-pass filtering conditions. C1 WALTER REED ARMY MED CTR,WASHINGTON,DC 20307. RP FABRY, DA (reprint author), MAYO CLIN & MAYO FDN,AUDIOL UNIT,200 1ST ST SW,ROCHESTER,MN 55905, USA. NR 15 TC 10 Z9 10 U1 0 U2 1 PU JOURNAL REHAB RES & DEV PI BALTIMORE PA DEPT OF VETERANS AFFAIRS REHABIL RES & DEVELOP CTR 103 SOUTH GAY STREET, BALTIMORE, MD 21202-4051 SN 0007-506X J9 J REHABIL RES DEV JI J. Rehabil. Res. Dev. PY 1993 VL 30 IS 3 BP 318 EP 325 PG 8 WC Rehabilitation SC Rehabilitation GA MR510 UT WOS:A1993MR51000005 PM 8126656 ER PT J AU GEDALIA, A GIANNINI, EH BREWER, EJ PERSON, DA AF GEDALIA, A GIANNINI, EH BREWER, EJ PERSON, DA TI PREVALENCE OF PERICARDIAL-EFFUSION BY ECHOCARDIOGRAPHY IN JUVENILE RHEUMATOID-ARTHRITIS SO JOURNAL OF RHEUMATOLOGY LA English DT Letter ID CARDIAC INVOLVEMENT C1 UNIV CINCINNATI,COLL MED,DEPT PEDIAT,DIV RHEUMATOL,CINCINNATI,OH 45221. BAYLOR COLL MED,DEPT PEDIAT,RHEUMATOL SECT,HOUSTON,TX 77030. UNIV HAWAII,JOHN A BURNS SCH MED,DEPT PEDIAT,HONOLULU,HI 96822. TRIPLER ARMY MED CTR,HONOLULU,HI 96859. RP GEDALIA, A (reprint author), LOUISIANA STATE UNIV,MED CTR,COLL MED,DEPT PEDIAT,NEW ORLEANS,LA 70112, USA. NR 6 TC 2 Z9 2 U1 0 U2 0 PU J RHEUMATOL PUBL CO PI TORONTO PA 920 YONGE ST, SUITE 115, TORONTO ON M4W 3C7, CANADA SN 0315-162X J9 J RHEUMATOL JI J. Rheumatol. PD JAN PY 1993 VL 20 IS 1 BP 206 EP 207 PG 2 WC Rheumatology SC Rheumatology GA KM695 UT WOS:A1993KM69500049 PM 8441159 ER PT J AU PETRALI, JP OGLESBY, SB HAMILTON, TA MILLS, KR AF PETRALI, JP OGLESBY, SB HAMILTON, TA MILLS, KR TI COMPARATIVE MORPHOLOGY OF SULFUR MUSTARD EFFECTS IN THE HAIRLESS GUINEA-PIG AND A HUMAN SKIN EQUIVALENT SO JOURNAL OF SUBMICROSCOPIC CYTOLOGY AND PATHOLOGY LA English DT Article DE SULFUR MUSTARD; HUMAN SKIN EQUIVALENT; ULTRASTRUCTURE; HAIRLESS GUINEA PIG; BASEMENT MEMBRANE ZONE ID TISSUE-SECTIONS AB A commercially available human skin equivalent (HSE) was used as an in vitro organotypic skin model to study temporal morphological effects of sulfur mustard gas (HD). Light and electron microscopic analyses of the HD-human skin equivalent model (HD-HSE) were compared to the HD-hairless guinea pig model (HD-HGP). HSE samples were exposed to 10 mul HD vapor for 8 min and harvested at selected times up to 24 h. Skin sites of HGP were exposed to the same vapor dose or to 2.0 mul liquid HD for 30 min and collected at 12 and 24 h. In both models, basal cells of the stratum germinativum were selectively affected. The HD-HSE study revealed that basal cell changes began 3 to 6 h following exposure. These early cellular changes included an acantholysis of some basal cells with widening of intercellular spaces, disruption of desmosomal attachments, nuclear pyknosis, perinuclear blebbing and repositioning of cytoplasmic tonofilaments to a perinuclear position. At 12 to 24 h, basal cell pathology progressed to diffuse swelling of endoplasmic reticula, cytoplasmic vacuolations and necrosis which now extended to supra basal cell layers. Comparing basement membrane zone effects, HD-HGP consistently developed characteristic microblisters at the dermal-epidermal junction; however, HD-HSE with its absence of a morphologically distinguishable basement membrane did not. Instead, cellular fragments, granules and debris accumulated early in this area to thicken regions usually assigned to the lamina lucida and lamina densa of a true basement membrane leading to complete separation of dermis from epidermis at later time periods. RP PETRALI, JP (reprint author), USA,CHEM DEF RES INST,ABERDEEN PROVING GROUND,MD 21010, USA. NR 12 TC 23 Z9 24 U1 0 U2 1 PU EDITRICE COMPOSITORI BOLOGNA PI BOLOGNA PA VIA STALINGRADO 97/2, I-40128 BOLOGNA, ITALY SN 1122-9497 J9 J SUBMICR CYTOL PATH JI J. Submicrosc. Cytol. Pathol. PD JAN PY 1993 VL 25 IS 1 BP 113 EP 118 PG 6 WC Pathology SC Pathology GA KM177 UT WOS:A1993KM17700013 PM 8462065 ER PT J AU WOODILLA, D BUONOMO, M BARON, I KATZ, RN WHALEN, T AF WOODILLA, D BUONOMO, M BARON, I KATZ, RN WHALEN, T TI ELEVATED-TEMPERATURE BEHAVIOR OF HIGH-STRENGTH SILICON-CARBIDE SO JOURNAL OF THE AMERICAN CERAMIC SOCIETY LA English DT Note AB The room- and high-temperature mechanical properties of a high-strength, sintered silicon carbide were evaluated. Room-temperature strength was measured in four-point bending. The room-temperature fracture toughness was determined using a precracked single-edge-notched beam (SENB) bridge indentation technique. The high-temperature behavior was evaluated using the stepped-temperature stress rupture (STSR) procedure. Both the room- and the high-temperature behavior are superior to those of previously tested commercial sintered alpha and beta silicon carbides. C1 USA,MAT TECHNOL LAB,WATERTOWN,MA 02172. FORD MOTOR CO,RES STAFF,DEARBORN,MI 48121. RP WOODILLA, D (reprint author), WORCESTER POLYTECH INST,DEPT MECH ENGN,WORCESTER,MA 01609, USA. NR 16 TC 7 Z9 7 U1 1 U2 1 PU AMER CERAMIC SOC PI WESTERVILLE PA 735 CERAMIC PLACE, PO BOX 6136, WESTERVILLE, OH 43081-6136 SN 0002-7820 J9 J AM CERAM SOC JI J. Am. Ceram. Soc. PD JAN PY 1993 VL 76 IS 1 BP 249 EP 252 DI 10.1111/j.1151-2916.1993.tb03719.x PG 4 WC Materials Science, Ceramics SC Materials Science GA LD474 UT WOS:A1993LD47400036 ER PT J AU ESHOW, MM SCHROEDER, JA AF ESHOW, MM SCHROEDER, JA TI IMPROVEMENTS IN HOVER DISPLAY DYNAMICS FOR A COMBAT HELICOPTER SO JOURNAL OF THE AMERICAN HELICOPTER SOCIETY LA English DT Article AB This paper describes a piloted simulation conducted on the NASA Ames Vertical Motion Simulator. The objective of the experiment was to investigate the handling qualities benefits attainable using new display law design methods for hover displays. The new display laws provide improved methods to specify the behavior of the display symbol that predicts the vehicle's ground velocity in the horizontal plane; it is the primary symbol that the pilot uses to control aircraft horizontal position. The display law design was applied to the Apache helmet-mounted display format, using the Apache vehicle dynamics to tailor the dynamics of the velocity predictor symbol. The representations of the Apache vehicle used in the display design process and in the simulation were derived from flight data. During the simulation, the new symbol dynamics were seen to improve the pilots' ability to maneuver about hover in poor visual cuing environments. The improvements were manifested in pilot handling qualities ratings and in measured task performance. The paper details the display design techniques, the experiment design and conduct, and the results. C1 NASA,AMES RES CTR,MOFFETT FIELD,CA 94035. RP ESHOW, MM (reprint author), USA,ATCOM,AEROFLIGHTDYNAM DIRECTORATE,MOFFETT FIELD,CA 94035, USA. NR 13 TC 1 Z9 1 U1 0 U2 0 PU AMER HELICOPTER SOC INC PI ALEXANDRIA PA 217 N WASHINGTON ST, ALEXANDRIA, VA 22314 SN 0002-8711 J9 J AM HELICOPTER SOC JI J. Am. Helicopter Soc. PD JAN PY 1993 VL 38 IS 1 BP 17 EP 28 PG 12 WC Engineering, Aerospace SC Engineering GA KT429 UT WOS:A1993KT42900002 ER PT J AU MURRI, GB OBRIEN, TK SALPEKAR, SA AF MURRI, GB OBRIEN, TK SALPEKAR, SA TI TENSION FATIGUE OF GLAS EPOXY AND GRAPHITE EPOXY TAPERED LAMINATES SO JOURNAL OF THE AMERICAN HELICOPTER SOCIETY LA English DT Article AB Symmetric tapered laminates with internally dropped plies were tested with two different layups, and two materials - S2/SP250 glass/epoxy and IM6/1827I graphite/epoxy. Layup A was a [0(9)/(+/-45)3/(+/-45)2]s laminate that reduced to a [0(9)/(+/-45)2]2 laminate by dropping the (+/-45)3 ply group. Layup B was a [0(7)/+/-45/(+/-45)3/0/+/-45/0]s, laminate that reduced to a [0(7)/+/-45/0/+/-45/0]s laminate in the same manner as layup A. The specimens were loaded in cyclic tension until they delaminated unstably. Each combination of material and layup had a different failure mode. Expected delamination failure loads were calculated for the different failure modes using mode I fatigue delamination characterization data and either calculated values of strain energy release rate, G, from a finite element (FE) analysis model of delamination along the taper, or, calculated G values for delamination from a matrix ply crack, modeled according to the actual observed specimen failures. Calculated delamination loads were compared to the experimental results. The agreement between the calculated and measured delamination onset loads was reasonable for each combination of layup and material. C1 ANALYT SERV & MAT INC,HAMPTON,VA. RP MURRI, GB (reprint author), NASA,LANGLEY RES CTR,USA,RES LAB,HAMPTON,VA 23665, USA. NR 23 TC 13 Z9 13 U1 0 U2 1 PU AMER HELICOPTER SOC INC PI ALEXANDRIA PA 217 N WASHINGTON ST, ALEXANDRIA, VA 22314 SN 0002-8711 J9 J AM HELICOPTER SOC JI J. Am. Helicopter Soc. PD JAN PY 1993 VL 38 IS 1 BP 29 EP 37 PG 9 WC Engineering, Aerospace SC Engineering GA KT429 UT WOS:A1993KT42900003 ER PT J AU PLICHTA, EJ BEHL, WK AF PLICHTA, EJ BEHL, WK TI THE RECHARGEABLE AMBIENT-TEMPERATURE ROCKING-CHAIR LITHIUM CELL EMPLOYING A SOLUTION OF LITHIUM HEXAFLUOROARSENATE IN ACETONITRILE AS THE ELECTROLYTE SO JOURNAL OF THE ELECTROCHEMICAL SOCIETY LA English DT Article ID CARBON; BATTERIES AB A rocking-chair ambient temperature rechargeable organic electrolyte cell employing thin films of titanium disulfide and lithium cobalt oxide as the negative and positive electrodes, respectively, is described. A 1.52M solution of lithium hexafluoroarsenate in acetonitrile with a conductivity of 0.0522 S/cm at 25-degrees-C was used as the electrolyte. The cell was assembled in the discharged state and after charging exhibited an open-circuit potential of 2.1 V. The discharge characteristics of the cell are presented at current densities between 2 to 20 mA/cm2. The cell also exhibited good cycle life and delivered 500 cycles. RP PLICHTA, EJ (reprint author), USA,RES LAB,ELECTR & POWER SOURCES DIRECTORATE,FT MONMOUTH,NJ 07703, USA. NR 18 TC 21 Z9 21 U1 0 U2 2 PU ELECTROCHEMICAL SOC INC PI PENNINGTON PA 10 SOUTH MAIN STREET, PENNINGTON, NJ 08534 SN 0013-4651 J9 J ELECTROCHEM SOC JI J. Electrochem. Soc. PD JAN PY 1993 VL 140 IS 1 BP 46 EP 49 DI 10.1149/1.2056107 PG 4 WC Electrochemistry; Materials Science, Coatings & Films SC Electrochemistry; Materials Science GA KF885 UT WOS:A1993KF88500014 ER PT J AU HILL, SC LEACH, DH CHANG, RK AF HILL, SC LEACH, DH CHANG, RK TI 3RD-ORDER SUM-FREQUENCY GENERATION IN DROPLETS - MODEL WITH NUMERICAL RESULTS FOR 3RD-HARMONIC GENERATION SO JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B-OPTICAL PHYSICS LA English DT Article ID STIMULATED RAMAN-SCATTERING; MORPHOLOGY-DEPENDENT RESONANCES; FOCUSED LASER-BEAM; LIQUID DROPLETS; FLUORESCENT SCATTERING; OPTICAL PROCESSES; SMALL PARTICLES; MICRODROPLETS; MICROSPHERES; ENHANCEMENT AB A steady-state model of third-order sum-frequency generation (TSFG) in liquid droplets is presented. A third-order polarization is generated in a droplet by stimulated Raman scattering (SRS) or by SRS in combination with fields at the incident laser frequency. This third-order polarization radiates inside the sphere as described in the general model of Chew et al. [Phys. Rev. A 19, 396 (1976)]. The frequency of the third-order polarization will only rarely be within a few linewidths of a high-Q output morphology-dependent resonance (MDR). The TSFG intensity is proportional to the spatial and frequency overlap between the generating polarization and the fields of the output modes. For a distribution of particle sizes, the probability of detecting TSFG increases with the density of output MDR's. Numerical results are presented for the specific case of the generation of the third harmonic of the first-order SRS. Although the comparison with experiment is only qualitative, the theory is consistent with experimental observations that TSFG in droplets is detectable at only a small fraction of the droplet sizes and is 4-6 orders of magnitude weaker than SRS. C1 NEW MEXICO STATE UNIV,DEPT ELECT & COMP ENGN,LAS CRUCES,NM 88003. YALE UNIV,DEPT APPL PHYS,NEW HAVEN,CT 06520. YALE UNIV,CTR LASER DIAGNOST,NEW HAVEN,CT 06520. RP HILL, SC (reprint author), ATMOSPHER SCI LAB,WHITE SANDS MISSILE RANGE,NM 88002, USA. NR 39 TC 24 Z9 24 U1 1 U2 4 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 SN 0740-3224 J9 J OPT SOC AM B JI J. Opt. Soc. Am. B-Opt. Phys. PD JAN PY 1993 VL 10 IS 1 BP 16 EP 33 DI 10.1364/JOSAB.10.000016 PG 18 WC Optics SC Optics GA KF646 UT WOS:A1993KF64600003 ER PT J AU LEACH, DH CHANG, RK ACKER, WP HILL, SC AF LEACH, DH CHANG, RK ACKER, WP HILL, SC TI 3RD-ORDER SUM-FREQUENCY GENERATION IN DROPLETS - EXPERIMENTAL RESULTS SO JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B-OPTICAL PHYSICS LA English DT Article ID STIMULATED RAMAN-SCATTERING; MORPHOLOGY-DEPENDENT RESONANCES; MICROMETER-SIZED DROPLETS; FOCUSED LASER-BEAM; BRILLOUIN-SCATTERING; LIQUID DROPLETS; EMISSION; SPECTROSCOPY; CAVITY; FIELDS AB New experimental third-order sum-frequency generation (TSFG) spectra are presented for CCl4 droplets. The droplet radii are discretely tuned over a size range in increments of 1 part in 6000. For each droplet radius only one or a few of the many possible TSFG peaks are dominant. Both low- and high-resolution TSFG spectra of D2O droplets are measured. The possible generating waves are the stimulated Raman radiation [known to occur at the morphology-dependent resonance (MDR) frequencies] and the internal fields at the incident laser frequency, which is usually not on a MDR. The experimental findings suggest that the resultant TSFG frequency must be near an output MDR. A physical description of the third-harmonic generation (THG) process in droplets is presented. MDR's are treated as traveling waves that rotate in the azimuthal direction. Their azimuthal phase velocities are derived, and the concept of phase matching among the MDR's is presented. The relation between phase matching and spatial overlap of MDR's is discussed. Reasons are presented for the low probability of having the THG or TSFG frequency on or near a MDR. C1 YALE UNIV,CTR LASER DIAGNOST,NEW HAVEN,CT 06520. TEXACO USA INC,DEPT RES & DEV,BEACON,NY 12508. USA,ATMOSPHER SCI LAB,WHITE SANDS MISSILE RANGE,NM 88002. RP LEACH, DH (reprint author), YALE UNIV,DEPT APPL PHYS,NEW HAVEN,CT 06520, USA. NR 36 TC 29 Z9 29 U1 0 U2 3 PU OPTICAL SOC AMER PI WASHINGTON PA 2010 MASSACHUSETTS AVE NW, WASHINGTON, DC 20036 SN 0740-3224 J9 J OPT SOC AM B JI J. Opt. Soc. Am. B-Opt. Phys. PD JAN PY 1993 VL 10 IS 1 BP 34 EP 45 DI 10.1364/JOSAB.10.000034 PG 12 WC Optics SC Optics GA KF646 UT WOS:A1993KF64600004 ER PT J AU STAPLER, JT CORNELL, JH AF STAPLER, JT CORNELL, JH TI DETERMINING MOISTURE ABSORPTION DESORPTION PROPERTIES OF COMMERCIAL MEMBRANES BY THERMOGRAVIMETRY (TG) SO JOURNAL OF THERMAL ANALYSIS LA English DT Article DE MOISTURE ADSORPTION DESORPTION PROPERTIES OF MEMBRANES; TG AB A series of different commercial membranes were characterized by their moisture absorption and desorption properties under controlled humidity and temperature conditions. This work was made possible by combining the features of a constant humidity conditioning chamber with those of a thermogravimetric (TG) apparatus. These two modules were interconnected by tubing, rotameters, an atmosphere-recycling microbellows pump and switching valves. Under programmed heating and isothermal conditions reproducible data were obtained in terms of weight-gain or weight-loss vs. time and pore size. Evaluation of the resulting TG curves allowed us to report reasonable differences in the materials, some of which had been previously surface-modified by the manufacturer. RP STAPLER, JT (reprint author), USA,CTR RES DEV & ENGN,NATICK,MA 01760, USA. NR 13 TC 3 Z9 3 U1 0 U2 0 PU JOHN WILEY & SONS LTD PI W SUSSEX PA BAFFINS LANE CHICHESTER, W SUSSEX, ENGLAND PO19 1UD SN 0368-4466 J9 J THERM ANAL JI J. Therm. Anal. PY 1993 VL 40 IS 3 BP 877 EP 886 DI 10.1007/BF02546846 PG 10 WC Thermodynamics; Chemistry, Analytical; Chemistry, Physical SC Thermodynamics; Chemistry GA LZ491 UT WOS:A1993LZ49100002 ER PT J AU KEMPPAINEN, BW TERSE, P MADHYASTHA, MS LENZ, SD PALMER, WG REIFENRATH, WG AF KEMPPAINEN, BW TERSE, P MADHYASTHA, MS LENZ, SD PALMER, WG REIFENRATH, WG TI IN-VITRO ASSESSMENT OF IN-VIVO DAMAGE TO THE BARRIER PROPERTIES OF PIG SKIN CAUSED BY A COMPLEX MIXTURE SO JOURNAL OF TOXICOLOGY-CUTANEOUS AND OCULAR TOXICOLOGY LA English DT Article ID PERCUTANEOUS-ABSORPTION; PENETRATION; PERMEATION AB The purpose of this study was to determine if an in vitro method can be used to measure changes in the barrier properties of skin caused by in vivo or in vitro topical exposure to a test chemical. The effect of a test chemical (liquid gun propellant [LP], a highly irritating mixture of hydroxylammonium nitrate, triethanolammonium nitrate, and water) on the barrier function of skin was assessed in vitro by measuring the penetration of [C-14]benzoic acid following exposure to LP. Weanling pigs were topically exposed to single doses (25 mul/cm2) of saline (control) or LP. LP-induced changes in the barrier properties of the skin were determined by measuring the permeability to [C-14]benzoic acid. After 1-5 days, pigs were euthanized and skin sections excised from the sites of application. Skin sections were mounted in in vitro penetration chambers to measure cumulative 24 hr penetration of [C-14]benzoic acid. Topical treatment with undiluted LP resulted in an 8.2-fold increase in permeability to [C-14]benzoic acid at 1 day after exposure. The permeability declined progressively during the succeeding 4 days. In a parallel study, untreated skin was excised, placed in penetration chambers, and then exposed to saline or LP for 1 day. In vitro skin exposure to LP resulted in a 3.9-fold increase in penetration of [C-14]benzoic acid. These studies demonstrate that the effect of LP on skin barrier properties is greatest at 1 day postexposure and steadily decreases thereafter and that both in vivo and in vitro dermal exposure to LP alters the barrier properties of skin. This in vitro method, which is the quantitation of transdermal transport of benzoic acid, can be used to assess the effect of chemical or physical agents on barrier function and time course of return to normal barrier function of skin. C1 USA,BIOMED RES & DEV LAB,FT DETRICK,MD. LETTERMAN ARMY INST RES,SAN FRANCISCO,CA 94129. RP KEMPPAINEN, BW (reprint author), AUBURN UNIV,COLL VET MED,AUBURN,AL 36849, USA. NR 12 TC 1 Z9 2 U1 0 U2 0 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0731-3829 J9 J TOXICOL-CUTAN OCUL JI J. Toxicol.-Cutan. Ocul. Toxicol. PY 1993 VL 12 IS 3 BP 239 EP 248 PG 10 WC Ophthalmology; Toxicology SC Ophthalmology; Toxicology GA LM473 UT WOS:A1993LM47300006 ER PT J AU SMITH, WJ SANDERS, KM RUDDLE, SE GROSS, CL AF SMITH, WJ SANDERS, KM RUDDLE, SE GROSS, CL TI CYTOMETRIC ANALYSIS OF DNA CHANGES INDUCED BY SULFUR MUSTARD SO JOURNAL OF TOXICOLOGY-CUTANEOUS AND OCULAR TOXICOLOGY LA English DT Article ID HUMAN-CELLS; TOXICITY; CULTURE AB Sulfur mustard is an alkylating agent that causes severe, potentially debilitating blisters following cutaneous exposure. Its mechanism of pathogenesis is unknown and no antidote exists. The biochemical basis of sulfur mustard's vesicating activity has been hypothesized to be a cascade of events beginning with alkylation of DNA. Using human cells in culture, we h assessed the effects of sulfur mustard on cell cycle activity using flow cytometry with propidium iodide. Two distinct patterns emerged: a G1/S interface block at concentrations equivalent to vesicating doses (>50 mu M) and a G2 block at 10-fold lower concentrations. In addition, noticeable increases in amount of dye uptake were observed at 4 and 24 hr after sulfur mustard exposure. These increases are believed to be related to DNA repair activities and can be prevented by treatment of the cells with niacinamide, which inhibits DNA repair. Other drugs that provide alternative alkylating sites or inhibit cell cycle progression were shown to lower the cytotoxicity of sulfur mustard and to protect against its direct DNA-damaging effects. RP SMITH, WJ (reprint author), USA,MED RES INST CHEM DEF,BIOCHEM PHARMACOL BRANCH,SGRD,UV,PB,APG,EA,ABERDEEN PROVING GROUND,MD 21010, USA. NR 18 TC 17 Z9 17 U1 0 U2 1 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0731-3829 J9 J TOXICOL-CUTAN OCUL JI J. Toxicol.-Cutan. Ocul. Toxicol. PY 1993 VL 12 IS 4 BP 337 EP 347 PG 11 WC Ophthalmology; Toxicology SC Ophthalmology; Toxicology GA MF288 UT WOS:A1993MF28800009 ER PT J AU SUN, DC BREWE, DE ABEL, PB AF SUN, DC BREWE, DE ABEL, PB TI SIMULTANEOUS PRESSURE MEASUREMENT AND HIGH-SPEED PHOTOGRAPHY STUDY OF CAVITATION IN A DYNAMICALLY LOADED JOURNAL BEARING SO JOURNAL OF TRIBOLOGY-TRANSACTIONS OF THE ASME LA English DT Article ID SQUEEZE FILM DAMPER; FORCE COEFFICIENTS; DISTRIBUTIONS; CONFIGURATION AB Cavitation of the oil film in a dynamically loaded journal bearing was studied using high-speed photography and pressure measurement simultaneously. Comparison of the visual and pressure data provided considerable insight into the occurrence and non-occurrence of cavitation. It was found that (1), cavitation typically occurred in the form of one bubble with the pressure in the cavitation bubble close to the absolute zero; and (2), for cavitation-producing operating conditions, cavitation did not always occur; with the oil film then supporting a tensile stress. C1 USA,AVIAT RES & TECHNOL ACT AVSCOM,LEWIS RES CTR,PROP DIRECTORATE,CLEVELAND,OH 44135. NASA,LEWIS RES CTR,CLEVELAND,OH 44135. RP SUN, DC (reprint author), SUNY BINGHAMTON,DEPT MECH & IND ENGN,BINGHAMTON,NY 13902, USA. NR 13 TC 17 Z9 18 U1 0 U2 3 PU ASME-AMER SOC MECHANICAL ENG PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 SN 0742-4787 J9 J TRIBOL-T ASME JI J. Tribol.-Trans. ASME PD JAN PY 1993 VL 115 IS 1 BP 88 EP 95 DI 10.1115/1.2920991 PG 8 WC Engineering, Mechanical SC Engineering GA KK632 UT WOS:A1993KK63200013 ER PT S AU ATKINS, JL PINTER, GG AF ATKINS, JL PINTER, GG BE Bianchi, C Bocci, V Carone, FA Rabkin, R TI EXTRAVASATION OF PLASMA-PROTEINS INTO THE RENAL INTERSTITIUM CONTRIBUTES TO THE PATHOPHYSIOLOGY OF DIABETIC NEPHROPATHY SO KIDNEY, PROTEINS AND DRUGS : AN UPDATE SE CONTRIBUTIONS TO NEPHROLOGY LA English DT Proceedings Paper CT 7TH INTERNATIONAL SYMP ON NEPHROLOGY CY OCT 14-16, 1991 CL MONTECATINI, ITALY SP TERME MONTECATINI, IST GENTILI, LAB GUIDOTTI RP ATKINS, JL (reprint author), WALTER REED ARMY INST RES,DEPT NEPHROL,BLDG 40,ROOM 3035,WASHINGTON,DC 20307, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU KARGER PI BASEL PA BASEL SN 0302-5144 BN 3-8055-5668-3 J9 CONTRIB NEPHROL JI Contrib.Nephrol. PY 1993 VL 101 BP 139 EP 142 PG 4 WC Biochemistry & Molecular Biology; Endocrinology & Metabolism; Pathology; Physiology; Urology & Nephrology SC Biochemistry & Molecular Biology; Endocrinology & Metabolism; Pathology; Physiology; Urology & Nephrology GA BX78S UT WOS:A1993BX78S00024 PM 8467667 ER PT J AU ABRUZZO, L JAFFE, ES CAMPO, E STETLERSTEVENSON, MA SANDER, C BAUER, F DOW, N MEDEIROS, LJ AF ABRUZZO, L JAFFE, ES CAMPO, E STETLERSTEVENSON, MA SANDER, C BAUER, F DOW, N MEDEIROS, LJ TI IMMATURE HEMATOPOIETIC-CELL NEOPLASMS WITH POTENTIAL FOR DIFFERENTIATION ALONG T-LYMPHOID AND MYELOID LINES SO LABORATORY INVESTIGATION LA English DT Meeting Abstract C1 NIH,BETHESDA,MD 20892. UNIV BARCELONA,BARCELONA 7,SPAIN. WALTER REED ARMY MED CTR,WASHINGTON,DC 20307. RHODE ISL HOSP,PROVIDENCE,RI 02902. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0023-6837 J9 LAB INVEST JI Lab. Invest. PD JAN PY 1993 VL 68 IS 1 BP A84 EP A84 PG 1 WC Medicine, Research & Experimental; Pathology SC Research & Experimental Medicine; Pathology GA KJ102 UT WOS:A1993KJ10200492 ER PT J AU BURKE, AP BENSON, W RIBAS, J ANDERSON, D CHU, WS SMIALEK, J VIRMANI, R AF BURKE, AP BENSON, W RIBAS, J ANDERSON, D CHU, WS SMIALEK, J VIRMANI, R TI LOCALIZATION OF HIV-1 RNA BY INSITU HYBRIDIZATION IN AUTOPSY TISSUES OF INTRAVENOUS DRUG-ADDICTS SO LABORATORY INVESTIGATION LA English DT Meeting Abstract C1 ARMED FORCES INST PATHOL,WASHINGTON,DC 20306. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. UNIV MARYLAND,BALTIMORE,MD 21201. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0023-6837 J9 LAB INVEST JI Lab. Invest. PD JAN PY 1993 VL 68 IS 1 BP A104 EP A104 PG 1 WC Medicine, Research & Experimental; Pathology SC Research & Experimental Medicine; Pathology GA KJ102 UT WOS:A1993KJ10200613 ER PT J AU BURKE, AP RIBAS, J ANDERSON, DW SMIALEK, JE AF BURKE, AP RIBAS, J ANDERSON, DW SMIALEK, JE TI HISTOPATHOLOGY OF LYMPHOID-TISSUES IN EARLY HIV-1 DISEASE, AND PREVALENCE OF WARTHIN-FINCKELDEY GIANT-CELLS SO LABORATORY INVESTIGATION LA English DT Meeting Abstract C1 ARMED FORCES INST PATHOL,WASHINGTON,DC 20306. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. UNIV MARYLAND,BALTIMORE,MD 21201. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0023-6837 J9 LAB INVEST JI Lab. Invest. PD JAN PY 1993 VL 68 IS 1 BP A87 EP A87 PG 1 WC Medicine, Research & Experimental; Pathology SC Research & Experimental Medicine; Pathology GA KJ102 UT WOS:A1993KJ10200510 ER PT J AU CARR, K HEFFES, C JIN, L DAVENPORT, R THOMPSON, N SISSON, J LLOYD, R AF CARR, K HEFFES, C JIN, L DAVENPORT, R THOMPSON, N SISSON, J LLOYD, R TI IMMUNOHISTOCHEMICAL ANALYSIS OF PAPILLARY AND ANAPLASTIC THYROID CARCINOMAS UTILIZING ANTIBODIES TO P53 PCNA AND KI-67 SO LABORATORY INVESTIGATION LA English DT Meeting Abstract C1 UNIV MICHIGAN,ANN ARBOR,MI 48109. USA,ARMED FORCES INST PATHOL,WASHINGTON,DC 20310. NR 0 TC 2 Z9 2 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0023-6837 J9 LAB INVEST JI Lab. Invest. PD JAN PY 1993 VL 68 IS 1 BP A37 EP A37 PG 1 WC Medicine, Research & Experimental; Pathology SC Research & Experimental Medicine; Pathology GA KJ102 UT WOS:A1993KJ10200216 ER PT J AU AYALA, E MARTINEZ, EM ENGHARDT, MH KIM, SH MURRAY, RN AF AYALA, E MARTINEZ, EM ENGHARDT, MH KIM, SH MURRAY, RN TI AN IMPROVED CYTOMEGALOVIRUS IMMUNOSTAINING METHOD SO LABORATORY MEDICINE LA English DT Article AB We describe a sensitive cytomegalovirus (CMV) immunostaining method in which casein, bovine serum albumin, and normal goat serum are used to block nonspecific sites, and acid-ethanol and levamisole are used to inactivate or inhibit endogenous alkaline phosphatase. We developed this technique while examining sections of intestine for detection of CMV infection. Using methods to eliminate background and nonspecific staining facilitates more reliable and interpretable cytomegalovirus immunostaining. RP AYALA, E (reprint author), BROOKE ARMY MED CTR,DEPT CLIN INVEST,FT SAM HOUSTON,TX 78234, USA. NR 0 TC 4 Z9 4 U1 0 U2 0 PU AMER SOC CLIN PATHOLOGISTS PI CHICAGO PA 2100 W HARRISON ST, CHICAGO, IL 60612 SN 0007-5027 J9 LAB MED JI Lab. Med. PD JAN PY 1993 VL 24 IS 1 BP 39 EP 43 PG 5 WC Medical Laboratory Technology SC Medical Laboratory Technology GA KD776 UT WOS:A1993KD77600010 ER PT B AU MAIT, JN AF MAIT, JN GP IEEE TI DESIGN OF DIFFRACTIVE OPTICAL-ELEMENTS FOR OPTICAL SIGNAL-PROCESSING SO LEOS '93 CONFERENCE PROCEEDINGS: IEEE LASERS AND ELECTRO-OPTICS SOCIETY 1993 ANNUAL MEETING LA English DT Proceedings Paper CT 6th Annual Meeting of the IEEE Lasers-and-Electro-Optics-Society (LEOS 93) CY NOV 15-18, 1993 CL SAN JOSE CONVENT CTR, SAN JOSE, CA SP IEEE, LASERS & ELECTRO OPT SOC HO SAN JOSE CONVENT CTR C1 USA,RES LAB,AMSRL SS IA,ADELPHI,MD 20783. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1263-5 J9 IEEE LEOS ANN MTG PY 1993 BP 59 EP 60 PG 2 WC Engineering, Electrical & Electronic; Optics SC Engineering; Optics GA BA47C UT WOS:A1993BA47C00024 ER PT J AU BUTLER, JD LEVIN, SW FACCHIANO, A MIELE, L MUKHERJEE, AB AF BUTLER, JD LEVIN, SW FACCHIANO, A MIELE, L MUKHERJEE, AB TI AMINO-ACID-COMPOSITION AND N-TERMINAL SEQUENCE OF PURIFIED CYSTINE BINDING-PROTEIN OF ESCHERICHIA-COLI SO LIFE SCIENCES LA English DT Article ID TRANSPORT AB Cystine Binding Protein (CBP), a commercially available crude protein extract obtained by osmotic shock of Escherichia coli (E. coli) , was studied to characterize further its cystine binding properties and to elucidate its cystine transport activity. We report here the amino acid composition, the N-terminal amino acid sequence analysis and some binding characteristics of the purified cystine binding component of CBP. A search of the Swiss-Prot version 20 data base revealed that this sequence is unique. C1 WALTER REED ARMY MED CTR,DEPT PEDIAT,EXCEPT FAMILY MEMBER PROGRAM,WASHINGTON,DC 20307. NICHHD,HUMAN GENET BRANCH,DEV GENET SECT,BETHESDA,MD 20892. RP BUTLER, JD (reprint author), NICHHD,GENET DIS INVOLVING SULPHUR METAB,BLDG 10,RM 10N308,BETHESDA,MD 20892, USA. RI Facchiano, Antonio/J-4744-2012; Facchiano, Antonio/K-5984-2016 OI Facchiano, Antonio/0000-0002-4243-2392 NR 11 TC 18 Z9 19 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0024-3205 J9 LIFE SCI JI Life Sci. PY 1993 VL 52 IS 14 BP 1209 EP 1215 DI 10.1016/0024-3205(93)90103-A PG 7 WC Medicine, Research & Experimental; Pharmacology & Pharmacy SC Research & Experimental Medicine; Pharmacology & Pharmacy GA KP469 UT WOS:A1993KP46900006 PM 8450713 ER PT J AU MATTHEW, CB AF MATTHEW, CB TI AMBIENT-TEMPERATURE EFFECTS ON THERMOREGULATION AND ENDURANCE IN ANTICHOLINESTERASE-TREATED RATS SO LIFE SCIENCES LA English DT Article ID PERFORMANCE; PHYSOSTIGMINE; HYPERTHERMIA; DIAZEPAM; ATROPINE; EXERCISE; MODE; HEAT AB In sedentary animals, physostigmine (PH) administration resulted in a decreased core temperature that is ambient temperature (Ta) dependent. PH administration in rats exercising on a treadmill (26-degrees-C, 50% rh, 11 m/min, 6-degrees incline) decremented endurance and increased rate of rise of core temperature (heating rate, HR). This study was undertaken to examine the effects of Ta on the endurance and thermoregulatory decrements of PH-treated running rats. Adult male rats (510-530g) were given either 0.2ml saline (C) or 100 ug/kg physostigmine salicylate in 0.2 ml saline via tail vein 15 min prior to the start of running to exhaustion at 10, 15, 26, or 30-degrees-C. In both C- and PH-treated groups, endurance decreased and HR increased with increasing Ta from 15 to 30-degrees-C. At 15 and 26-degrees-C the C rats ran significantly (p<.05) longer and had significantly lower HR than the PH rats: C15 = 90+/-8 min, 0.022+/-0.006-degrees-C/min; C26 = 67+/-6, 0.051+/-0.007; PH15 = 57+/-5, 0.052+/-0.008; and PH26 = 43+/-6, 0.092+/-0.007. At 10 and 30-degrees-C there were no significant differences between C and PH-treated rats. A Ta of 30-degrees-C was too high for effective cooling in either group, and at 10-degrees-C both groups were able to dissipate heat despite the increased metabolic rate of the PH-treated rats. The PH-treated rat model of cholinergic drug effect is useful at a Ta of 15 and 26-degrees-C. RP MATTHEW, CB (reprint author), USA,ENVIRONM MED RES INST,NATICK,MA 01760, USA. NR 27 TC 3 Z9 3 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0024-3205 J9 LIFE SCI JI Life Sci. PY 1993 VL 52 IS 16 BP 1343 EP 1349 DI 10.1016/0024-3205(93)90169-4 PG 7 WC Medicine, Research & Experimental; Pharmacology & Pharmacy SC Research & Experimental Medicine; Pharmacology & Pharmacy GA KR481 UT WOS:A1993KR48100002 PM 8464333 ER PT S AU LELIS, AJ OLDHAM, TR AF LELIS, AJ OLDHAM, TR BE Celler, GK Maldonado, JR TI EFFECTS OF SIMULATED X-RAY-LITHOGRAPHY EXPOSURES ON SUBMICRON-CHANNEL MOSFETS SO MATERIALS ASPECTS OF X-RAY LITHOGRAPHY SE MATERIALS RESEARCH SOCIETY SYMPOSIUM PROCEEDINGS LA English DT Proceedings Paper CT Symposium on Materials Aspects of X-Ray Lithography, as part of Annual Spring Meeting of the Materials-Research-Society CY APR 12-14, 1993 CL SAN FRANCISCO, CA SP MAT RES SOC, ADV RES PROJECTS AGCY C1 USA,RES LAB,AMSRL WT NG,ADELPHI,MD 20783. NR 0 TC 1 Z9 1 U1 0 U2 0 PU MATERIALS RESEARCH SOC PI PITTSBURGH PA 9800 MCKNIGHT RD, SUITE 327, PITTSBURGH, PA 15237 SN 0272-9172 BN 1-55899-202-2 J9 MATER RES SOC SYMP P PY 1993 VL 306 BP 57 EP 62 DI 10.1557/PROC-306-57 PG 6 WC Materials Science, Multidisciplinary; Physics, Applied SC Materials Science; Physics GA BZ54W UT WOS:A1993BZ54W00007 ER PT J AU RASZKA, WV SHOUPE, BL EDWARDS, EG AF RASZKA, WV SHOUPE, BL EDWARDS, EG TI ISOLATED PRIMARY CUTANEOUS ASPERGILLOSIS OF THE LABIA SO MEDICAL AND PEDIATRIC ONCOLOGY LA English DT Article DE ASPERGILLOSIS; ACUTE NONLYMPHOCYTIC LEUKEMIA; AMPHOTERICIN-B; GRANULOCYTE-COLONY STIMULATING FACTOR ID INVASIVE ASPERGILLOSIS; INFECTIONS AB Isolated cutaneous aspergillosis is a rare complication of severe immunocompromised states. We describe a case of isolated cutaneous aspergillosis of the labia minora in an adolescent undergoing treatment for relapsed acute non-lymphocytic leukemia. The patient was successfully treated with a regimen that consisted of amphotericin B, granulocyte-colony stimulating factor, and surgical debridement. RP RASZKA, WV (reprint author), WALTER REED ARMY MED CTR,DEPT PEDIAT,WASHINGTON,DC 20307, USA. NR 18 TC 6 Z9 6 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0098-1532 J9 MED PEDIATR ONCOL JI Med. Pediatr. Oncol. PY 1993 VL 21 IS 5 BP 375 EP 378 DI 10.1002/mpo.2950210514 PG 4 WC Oncology; Pediatrics SC Oncology; Pediatrics GA LB938 UT WOS:A1993LB93800013 PM 8492754 ER PT J AU CARLIN, K CARLIN, S AF CARLIN, K CARLIN, S TI POSSIBLE ETIOLOGY FOR EUTHYROID SICK SYNDROME SO MEDICAL HYPOTHESES LA English DT Article ID 3,5,3'-TRIIODOTHYROACETIC ACID; HUMAN-SERUM; TRIIODOTHYRONINE RECEPTORS; THYROID-HORMONES; PRE-ALBUMIN; BINDING; RAT; PITUITARY; ANALOGS; METABOLISM AB Euthyroid sick syndrome is possibly due to an increase in Triac (a T3 analogue) and/or Tetrac (a T4 analogue). Triac and/or Tetrac possibly feed back on the pituitary/hypothalamus region and cause a secondary hypothyroidism. This is possibly analogous to such diverse conditions as fetal thyroid function and black bear hibernation. RP CARLIN, K (reprint author), BROOKE ARMY MED CTR,DEPT ENDOCRINOL,SAN ANTONIO,TX 78234, USA. NR 61 TC 11 Z9 11 U1 0 U2 0 PU CHURCHILL LIVINGSTONE PI EDINBURGH PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE, LEITH WALK, EDINBURGH, MIDLOTHIAN, SCOTLAND EH1 3AF SN 0306-9877 J9 MED HYPOTHESES JI Med. Hypotheses PD JAN PY 1993 VL 40 IS 1 BP 38 EP 43 DI 10.1016/0306-9877(93)90194-U PG 6 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA KH940 UT WOS:A1993KH94000007 PM 8455465 ER PT B AU CHIN, ESC BIEDERMAN, RR AF CHIN, ESC BIEDERMAN, RR BE Kanne, WR Johnson, GWE Braun, JD Louthan, MR TI MICROSTRUCTURAL EVOLUTION UPON HEAT-TREATMENT OF TIB2 REINFORCED TI-48 AT-PERCENT AL SO METALLOGRAPHIC CHARACTERIZATION OF METALS AFTER WELDING, PROCESSING AND SERVICE SE MICROSTRUCTURAL SCIENCE LA English DT Proceedings Paper CT Technical Meeting of the 25th Annual Convention of the International-Metallographic-Society CY AUG 04-05, 1992 CL DENVER, CO SP INT METALLOG SOC, ASM INT C1 USA,RES LAB,MAT DIRECTORATE,SLCMT,MEM,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASM INTERNATIONAL PI MATERIALS PARK PA 9503 KINSMAN RD, MATERIALS PARK, OH 44073 BN 0-87170-471-4 J9 MICROSTR SC PY 1993 VL 20 BP 131 EP 139 PG 9 WC Materials Science, Characterization & Testing SC Materials Science GA BZ94J UT WOS:A1993BZ94J00009 ER PT B AU CHATTERJEE, TK HESPOS, M KUMAR, P POSTHILL, JB AF CHATTERJEE, TK HESPOS, M KUMAR, P POSTHILL, JB BE Kanne, WR Johnson, GWE Braun, JD Louthan, MR TI MICROSTRUCTURE CHARACTERIZATION AND MECHANICAL-BEHAVIOR OF TANTALUM FOR DIFFERENT MANUFACTURING PROCESSES SO METALLOGRAPHIC CHARACTERIZATION OF METALS AFTER WELDING, PROCESSING AND SERVICE SE MICROSTRUCTURAL SCIENCE LA English DT Proceedings Paper CT Technical Meeting of the 25th Annual Convention of the International-Metallographic-Society CY AUG 04-05, 1992 CL DENVER, CO SP INT METALLOG SOC, ASM INT C1 USA,CTR RES DEV & ENGN CTR,PICATINNY ARSENAL,NJ 07806. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASM INTERNATIONAL PI MATERIALS PARK PA 9503 KINSMAN RD, MATERIALS PARK, OH 44073 BN 0-87170-471-4 J9 MICROSTR SC PY 1993 VL 20 BP 499 EP 508 PG 10 WC Materials Science, Characterization & Testing SC Materials Science GA BZ94J UT WOS:A1993BZ94J00034 ER PT J AU WANG, Z CHEN, TK LLOYD, DJ AF WANG, Z CHEN, TK LLOYD, DJ TI STRESS-DISTRIBUTION IN PARTICULATE-REINFORCED METAL-MATRIX COMPOSITES SUBJECTED TO EXTERNAL LOAD SO METALLURGICAL TRANSACTIONS A-PHYSICAL METALLURGY AND MATERIALS SCIENCE LA English DT Article ID ELASTIC-PLASTIC ANALYSIS; AL-SIC COMPOSITES; EUTECTIC COMPOSITES; DISLOCATION GENERATION; THERMAL-EXPANSION; RESIDUAL-STRESSES; SHORT FIBER; DEFORMATION AB Finite element calculations were carried out to study the stress distribution in particulate SiC-reinforced Al metal-matrix composites (MMCs) subjected to external load. The results showed that, in addition to the effect of the aspect ratio of the reinforcement, particle distribution and grouping behavior-clustering, resulting from the casting process n the present materials. also contribute considerably to the nonuniform stress distribution in the material. The triaxial stress state around a particle or inside a particle cluster may change the von Mises stress and result in plastic deformation features, such as strain localization. Furthermore, the relative orientation of the particle distribution to the external load was found to be important to the stress distribution. As the applied stress increases, the state of triaxial stress inside a cluster appears to promote the early particle cracking, interface debonding, and void formation in the ductile matrix. Experimental observations of slip band distribution and other features in compression tests are consistent with the calculated results. C1 USA,MAT TECHNOL LAB,WATERTOWN,MA 02172. ALCAN INT LTD,KINGSTON RES CTR,KINGSTON K7L 5L9,ONTARIO,CANADA. RP WANG, Z (reprint author), UNIV TORONTO,DEPT MET & MAT SCI,TORONTO M5S 1A4,ONTARIO,CANADA. NR 26 TC 101 Z9 104 U1 0 U2 11 PU MINERALS METALS MATERIALS SOC PI WARRENDALE PA 420 COMMONWEALTH DR, WARRENDALE, PA 15086 SN 0360-2133 J9 METALL TRANS A PD JAN PY 1993 VL 24 IS 1 BP 197 EP 207 DI 10.1007/BF02669616 PG 11 WC Materials Science, Multidisciplinary SC Materials Science GA KJ806 UT WOS:A1993KJ80600022 ER PT J AU MACHAN, TR AF MACHAN, TR TI SOME REFLECTIONS ON RORTY,RICHARD PHILOSOPHY SO METAPHILOSOPHY LA English DT Article RP MACHAN, TR (reprint author), US MIL ACAD,DEPT PHILOSOPHY,W POINT,NY 10996, USA. NR 12 TC 1 Z9 1 U1 0 U2 0 PU BLACKWELL PUBL LTD PI OXFORD PA 108 COWLEY RD, OXFORD, OXON, ENGLAND OX4 1JF SN 0026-1068 J9 METAPHILOSOPHY JI Metaphilosophy PD JAN-APR PY 1993 VL 24 IS 1-2 BP 123 EP 135 DI 10.1111/j.1467-9973.1993.tb00451.x PG 13 WC Philosophy SC Philosophy GA LN205 UT WOS:A1993LN20500011 ER PT J AU MANEEKARN, N MORITA, K TANAKA, M IGARASHI, A USAWATTANAKUL, W SIRISANTHANA, V INNIS, BL SITTISOMBUT, N NISALAK, A NIMMANITYA, S AF MANEEKARN, N MORITA, K TANAKA, M IGARASHI, A USAWATTANAKUL, W SIRISANTHANA, V INNIS, BL SITTISOMBUT, N NISALAK, A NIMMANITYA, S TI APPLICATIONS OF POLYMERASE CHAIN-REACTION FOR IDENTIFICATION OF DENGUE VIRUSES ISOLATED FROM PATIENT SERA SO MICROBIOLOGY AND IMMUNOLOGY LA English DT Article DE POLYMERASE CHAIN REACTION; RT-PCR; DENGUE INFECTION ID AMINO-ACID SEQUENCE; NUCLEOTIDE-SEQUENCE; STRUCTURAL PROTEINS; INDIRECT IMMUNOFLUORESCENCE; ENZYMATIC AMPLIFICATION; NONSTRUCTURAL PROTEINS; MONOCLONAL-ANTIBODIES; RAPID IDENTIFICATION; JAMAICA GENOTYPE; PERIPHERAL-BLOOD AB A simple and sensitive procedure of reverse transcriptase polymerase chain reaction (RT-PCR) was developed previously such that all 4 serotypes of dengue viruses could be detected and their serotypes identified simultaneously in a single-step procedure. In this study we compared the RT-PCR with a conventional immunoperoxidase (PAP) staining method for the identification of dengue viruses currently isolated from patient sera. Sixty-six sera taken from dengue hemorrhagic fever (DHF) patients were subjected to virus isolation by inoculating onto C6/36 cell cultures. Screening for the presence of dengue viruses in culture fluids was done after 7 days of incubation by PAP staining using hyperimmune rabbit anti-dengue virus antibody as the primary reagent. Dengue viruses in positive cultures were further identified for their serotypes by PAP using type-specific monoclonal antibodies (MAb) and by RT-PCR. Thirty-two out of the 66 serum specimens tested (48.5%) were positive for dengue viruses. Of these, 5 were type 1 (DEN-1), 25 were type 2 (DEN-2) and 2 contained both DEN-1 and DEN-2. All cultures that were positive by PAP method were also positive by RT-PCR and vice versa. Thus, the results obtained by RT-PCR were in good agreement with those by PAP. It is important to point out that while all 5 DEN-1 isolates reacted readily with the MAb IFI, only 2 of them could be identified by the MAb 15F3, Our data suggest that antigenic variation among DEN-1 isolates occur frequently and this should be taken into consideration in the selection of appropriate type-specific MAb for serotyping of dengue viruses. We also demonstrated dual infection of DEN-1 and DEN-2 in two patients' sera by RT-PCR. C1 NAGASAKI UNIV,INST TROP MED,DEPT VIROL,12-4 SAKAMOTO MACHI,NAGASAKI 852,JAPAN. MAHIDOL UNIV,FAC TROP MED,DEPT MICROBIOL & IMMUNOL,BANGKOK 10700,THAILAND. CHIANG MAI UNIV,FAC MED,DEPT MICROBIOL,CHIANG MAI 50002,THAILAND. ARMED FORCES RES INST MED SCI,DEPT VIROL,BANGKOK,THAILAND. MINIST PUBL HLTH,CHILDRENS HOSP,DIV INFECT DIS,BANGKOK,THAILAND. NAGASAKI UNIV,INST TROP MED,DEPT VIROL,NAGASAKI 852,JAPAN. CHIANG MAI UNIV,FAC MED,DEPT PEDIAT,CHIANG MAI 50002,THAILAND. NR 27 TC 23 Z9 25 U1 0 U2 0 PU CENTER ACADEMIC PUBL JAPAN PI TOKYO PA 4-16 YAYOI 2-CHOME, BUNKYO-KU, TOKYO 113, JAPAN SN 0385-5600 J9 MICROBIOL IMMUNOL JI Microbiol. Immunol. PY 1993 VL 37 IS 1 BP 41 EP 47 PG 7 WC Immunology; Microbiology SC Immunology; Microbiology GA KM734 UT WOS:A1993KM73400006 PM 8474356 ER PT J AU HIGGINS, TP AF HIGGINS, TP TI DIRECT OPTICAL SUBHARMONICALLY INJECTION-LOCKED MESFET OSCILLATORS SO MICROWAVE AND OPTICAL TECHNOLOGY LETTERS LA English DT Article DE DIRECT OPTICAL INJECTION LOCKING; SUBHARMONIC; MICROWAVES; LASER DIODE; MESFET OSCILLATOR AB Reported here are the results of direct optical subharmonically injection-locked oscillators at 5.455 and 15.011 GHz. Multiplication of subharmonics was achieved mainly by overmodulation of a laser diode. Significant locking ranges were attained, and subharmonic factors of up to 1/15 were used. RP HIGGINS, TP (reprint author), USA,LABCOM,ELECTR TECHNOL & DEVICES LAB,FT MONMOUTH,NJ 07703, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU JOHN WILEY & SONS INC PI NEW YORK PA 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0895-2477 J9 MICROW OPT TECHN LET JI Microw. Opt. Technol. Lett. PD JAN PY 1993 VL 6 IS 1 BP 33 EP 36 DI 10.1002/mop.4650060110 PG 4 WC Engineering, Electrical & Electronic; Optics SC Engineering; Optics GA KF094 UT WOS:A1993KF09400009 ER PT J AU CANCIO, LC AF CANCIO, LC TI CHEMICAL CASUALTY DECONTAMINATION BY MEDICAL PLATOONS IN THE 82D AIRBORNE DIVISION SO MILITARY MEDICINE LA English DT Article AB Chemical casualty decontamination must be carried out as far forward as possible to limit spread of agents and to render aid as quickly as possible. Traditionally, decontamination in the 82d Airborne Division has been provided by the Forward Support Medical Company. During Operation Desert Shield, the Division's Medical Platoons acquired the ability to decontaminate casualties for the first time. The author describes a detailed plan for casualty decontamination by Medical Platoons developed for this purpose. Dedicated rehearsal of decontamination and other aspects of chemical casualty care is essential. RP CANCIO, LC (reprint author), BROOKE ARMY MED CTR,DEPT SURG,FT SAM HOUSTON,TX 78234, USA. NR 0 TC 9 Z9 9 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD JAN PY 1993 VL 158 IS 1 BP 1 EP 5 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA KH785 UT WOS:A1993KH78500007 PM 8437732 ER PT J AU POWERS, JM AF POWERS, JM TI NO LONGER DESTINED TO EAT THEIR YOUNG - SATISFACTION AMONG ARMY FAMILY-PRACTICE FACULTY SO MILITARY MEDICINE LA English DT Article AB In January 1987, all 63 faculty members at Army Family Practice Residencies received satisfaction questionnaires. Fifty nine faculty (93.8%) responded with 40 (67.8%) being satisfied and 19 (32.2%) dissatisfied. Compared to faculty 7 years prior these faculty are slightly older, have more practice experience, more opportunities for fellowship training, and are less likely both to have remaining mandatory military obligation and to leave the Army after 3 years. The key areas of faculty development, control over professional life, administration, and departmental goals and objectives truly discriminated satisfaction from dissatisfaction. A strategy to systematically develop potential faculty and reduce dissatisfaction is proposed. RP POWERS, JM (reprint author), TRIPLER ARMY MED CTR,DEPT FAMILY PRACTICE,HONOLULU,HI 96859, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD JAN PY 1993 VL 158 IS 1 BP 32 EP 37 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA KH785 UT WOS:A1993KH78500015 PM 8437738 ER PT J AU RUBERTONE, MV DEFRAITES, RF KRAUSS, MR BRANDT, CA AF RUBERTONE, MV DEFRAITES, RF KRAUSS, MR BRANDT, CA TI AN OUTBREAK OF HEPATITIS-A DURING A MILITARY FIELD TRAINING EXERCISE SO MILITARY MEDICINE LA English DT Article AB Hepatitis A continues to pose a preventable threat to modern day military forces. We describe a food-borne outbreak of hepatitis A during a field training exercise resulting in 22 ill soldiers and over 300 lost work days. Among the population at risk, the secondary attack rate was 19.6%. Faced with epidemic disease occurrence, epidemiologic investigation of potential cases and aggressive use of post-exposure prophylaxis is recommended in a field setting. Although immune serum globulin is likely to reduce transmission, not all cases of acute hepatitis A will be prevented by this action. RP RUBERTONE, MV (reprint author), WALTER REED ARMY INST RES,DIV PREVENT MED,WASHINGTON,DC 20307, USA. NR 0 TC 11 Z9 12 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD JAN PY 1993 VL 158 IS 1 BP 37 EP 41 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA KH785 UT WOS:A1993KH78500016 PM 8382351 ER PT J AU RITCHIE, EC AF RITCHIE, EC TI FURTHER CASES OF GAS MASK PHOBIA - RESPONSE SO MILITARY MEDICINE LA English DT Letter RP RITCHIE, EC (reprint author), WALTER REED ARMY MED CTR,DEPT PSYCHIAT,WASHINGTON,DC 20307, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU ASSN MILITARY SURG US PI BETHESDA PA 9320 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0026-4075 J9 MIL MED JI Milit. Med. PD JAN PY 1993 VL 158 IS 1 BP A4 EP A4 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA KH785 UT WOS:A1993KH78500002 ER PT J AU WILSON, CM VOLKMAN, SK THAITHONG, S MARTIN, RK KYLE, DE MILHOUS, WK WIRTH, DF AF WILSON, CM VOLKMAN, SK THAITHONG, S MARTIN, RK KYLE, DE MILHOUS, WK WIRTH, DF TI AMPLIFICATION OF PFMDR1 ASSOCIATED WITH MEFLOQUINE AND HALOFANTRINE RESISTANCE IN PLASMODIUM-FALCIPARUM FROM THAILAND SO MOLECULAR AND BIOCHEMICAL PARASITOLOGY LA English DT Article DE MALARIA; PLASMODIUM-FALCIPARUM; DRUG RESISTANCE; MULTIPLE DRUG-RESISTANT; MEFLOQUINE; HALOFANTRINE ID CHLOROQUINE-RESISTANCE; MULTIDRUG-RESISTANCE; GENE; INVITRO; MECHANISM; CROSS AB Drug resistance in Plasmodium falciparum is an expanding problem in most endemic areas. Recent studies have suggested the potential involvement of genes in the MDR gene family in resistance to quinoline-containing compounds in P. falciparum. In this study a molecular analysis of pfmdr1 in recent isolates from Thailand was done (1) to further examine the role of pfmdr1 in drug-resistant isolates and (2) to examine the reported association of pfmdr1 intragenic alleles and chloroquine resistance. Most of the isolates (10 of 11) were resistant to all compounds tested. Analysis of pfmdr1 revealed an apparent association between increased gene copy number and increased level of expression of pfmdr1 and decreased susceptibility to mefloquine and halofantrine. Sequence analysis of pfmdr1 in these isolates revealed no association of intragenic alleles with chloroquine resistance. C1 HARVARD UNIV,SCH PUBL HLTH,DEPT TROP PUBL HLTH,665 HUNTINGTON AVE,BOSTON,MA 02115. CHULALONGKORN UNIV,WHO,CTR COLLABORATING,BANGKOK 5,THAILAND. WALTER REED ARMY INST RES,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307. FU NIAID NIH HHS [AI-27872, K11 AI00892-04, T32AI-07350] NR 26 TC 210 Z9 215 U1 0 U2 6 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0166-6851 J9 MOL BIOCHEM PARASIT JI Mol. Biochem. Parasitol. PD JAN PY 1993 VL 57 IS 1 BP 151 EP 160 DI 10.1016/0166-6851(93)90252-S PG 10 WC Biochemistry & Molecular Biology; Parasitology SC Biochemistry & Molecular Biology; Parasitology GA KG418 UT WOS:A1993KG41800014 PM 8426608 ER PT J AU AVIS, I JETT, M KASPRZYK, PG CUTTITTA, F TRESTON, AM MANECKJEE, R MULSHINE, JL AF AVIS, I JETT, M KASPRZYK, PG CUTTITTA, F TRESTON, AM MANECKJEE, R MULSHINE, JL TI EFFECT OF GASTRIN-RELEASING PEPTIDE ON THE PANCREATIC TUMOR-CELL LINE (CAPAN) SO MOLECULAR CARCINOGENESIS LA English DT Note DE PANCREATIC CANCER; GROWTH FACTORS; GASTRIN-RELEASING PEPTIDE RECEPTORS ID LUNG-CANCER; INOSITOL PHOSPHATES; AUTOCRINE GROWTH; CALCIUM SIGNAL; 2H3 CELLS; BOMBESIN; RECEPTORS; EXPRESSION; ANTAGONIST; RAT AB TheGastrin-releasing peptide (GRP) has previously been shown to be an autocrine growth factor for small cell lung cancer, and our objective in the study presented here was to determine whether GRP has a similar role in pancreatic cancer. Using I-125-GRP, We demonstrated binding to specific, saturable, high-affinity sites (K-d = 1 nM; B-max = 245 fmol/mg protein) in membrane preparations from the pancreatic tumor cell line Capan. The receptors were found to be biologically active. In whole cells, a GRP analogue bound to these receptors and stimulated rapid transfer of tritium from the tritiated lipid inositol pool to inositol triphosphates. Exogenous GRP addition stimulated incorporation of [H-3]thymidine into DNA 20-60%. This stimulatory effect was blocked by the addition of a monoclonal antibody that complexed specifically with the receptor-binding portion of the peptide. In addition, the monoclonal antibody inhibited the growth of Capan cells in an in vitro growth assay without exogenous peptide. Bombesin receptor-specific antagonists also inhibited growth in a similar fashion. These data suggest that paracrine production of GRP may be important in pancreatic tumor growth, or that low-levels of a GRP-like peptide may play an autocrine role in this tumor. (C) 1993 Wiley-Liss, Inc. C1 NCI,DIV CANC PREVENT & CANC CONTROL,BIOMARKERS & PREVENT RES BRANCH,ROCKVILLE,MD 20850. WALTER REED ARMY RES CTR,DIV PATHOL,WASHINGTON,DC. ONCOLOGIX INC,GAITHERSBURG,MD. BAYLOR UNIV,SIMMONS CANC CTR,DALLAS,TX. NR 35 TC 18 Z9 18 U1 1 U2 1 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0899-1987 J9 MOL CARCINOGEN JI Mol. Carcinog. PY 1993 VL 8 IS 4 BP 214 EP 220 DI 10.1002/mc.2940080403 PG 7 WC Biochemistry & Molecular Biology; Oncology SC Biochemistry & Molecular Biology; Oncology GA MP108 UT WOS:A1993MP10800002 PM 8280369 ER PT B AU TEETER, AM AF TEETER, AM BE Mehta, AJ TI SUSPENDED TRANSPORT AND SEDIMENT-SIZE TRANSPORT EFFECTS IN A WELL-MIXED, MESO-TIDAL ESTUARY SO NEARSHORE AND ESTUARINE COHESIVE SEDIMENT TRANSPORT SE COASTAL AND ESTUARINE STUDIES LA English DT Proceedings Paper CT Nearshore and Estuarine Cohesive Sediment Transport Workshop CY APR, 1991 CL ST PETERSBURG, FL C1 USA,DIV ESTUARIES,HYDRAUL LAB,EXPT STN,VICKSBURG,MS 39180. NR 0 TC 3 Z9 3 U1 0 U2 1 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 BN 0-87590-256-1 J9 COAST ESTUAR STUD PY 1993 VL 42 BP 411 EP 429 PG 19 WC Engineering, Civil; Geosciences, Multidisciplinary; Oceanography; Water Resources SC Engineering; Geology; Oceanography; Water Resources GA BZ42R UT WOS:A1993BZ42R00024 ER PT S AU CLAYBAUGH, JR UYEHARA, CFT AF CLAYBAUGH, JR UYEHARA, CFT BE North, WG Moses, AM Share, L TI METABOLISM OF NEUROHYPOPHYSEAL HORMONES SO NEUROHYPOPHYSIS : A WINDOW ON BRAIN FUNCTION SE ANNALS OF THE NEW YORK ACADEMY OF SCIENCES LA English DT Proceedings Paper CT 5TH INTERNATIONAL CONF ON THE NEUROPHYPOPHYSIS - NEUROHYPOPHYSIS : A WINDOW ON BRAIN FUNCTION CY JUL 16-20, 1992 CL DARTMOUTH COLL, HANOVER, NH SP NEW YORK ACAD SCI, FERRING PHARM, HARLAN SPRAGUE DAWLEY, R W JOHNSON PHARM RES INST, ORGANON INT, PFIZER CENT RES, SMITHKLINE BEECHAM PHARM HO DARTMOUTH COLL RP CLAYBAUGH, JR (reprint author), TRIPLER ARMY MED CTR,DEPT CLIN INVEST,HONOLULU,HI 96859, USA. NR 0 TC 13 Z9 13 U1 0 U2 3 PU NEW YORK ACAD SCIENCES PI NEW YORK PA NEW YORK SN 0077-8923 BN 0-89766-773-5 J9 ANN NY ACAD SCI JI Ann.NY Acad.Sci. PY 1993 VL 689 BP 250 EP 268 DI 10.1111/j.1749-6632.1993.tb55552.x PG 19 WC Endocrinology & Metabolism; Neurosciences; Physiology SC Endocrinology & Metabolism; Neurosciences & Neurology; Physiology GA BY94A UT WOS:A1993BY94A00021 PM 8373016 ER PT J AU KRUMINS, SA BROOMFIELD, CA AF KRUMINS, SA BROOMFIELD, CA TI C-TERMINAL SUBSTANCE-P FRAGMENTS ELICIT HISTAMINE-RELEASE FROM A MURINE MAST-CELL LINE SO NEUROPEPTIDES LA English DT Article ID HUMAN-SKIN; PEPTIDES; RAT; NEUROPEPTIDES; METABOLISM; BINDING AB Incubation of mouse mast cells with C-terminal substance P fragments in the micromolar range caused a release of histamine. Maximum release was observed with the tetrapeptide SP(8-11), followed by the tripeptide SP(9-11). SP((3-11) and SP(5-11) were nearly equipotent, while SP(4-11) caused only a slight histamine release. The substance P parent molecule and the N-terminal substance P fragments SP(1-4), SP(1-6) and SP(1-7) evoked no release of histamine. In confirmation of our previous findings, incubation with neurokinin A caused a release comparable to that of SP(8-11). Whereas neurokinin A-induced release was partially preventable by pretreating the cells with the NK2 receptor-selective antagonist cyclo(Gln-Trp-Phe-(R)Gly[ANC-2]Leu-Met), SP(8-11)-induced release was completely abolished by such treatment. The results provide the first evidence for the involvement of NK2 tachykinin receptors in the release of histamine by C-terminal substance P fragments. C1 USA,MED RES INST CHEM DEF,BIOCHEM PHARMACOL BRANCH,ABERDEEN PROVING GROUND,MD 21010. NR 22 TC 43 Z9 44 U1 0 U2 0 PU CHURCHILL LIVINGSTONE PI EDINBURGH PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE, LEITH WALK, EDINBURGH, MIDLOTHIAN, SCOTLAND EH1 3AF SN 0143-4179 J9 NEUROPEPTIDES JI Neuropeptides PD JAN PY 1993 VL 24 IS 1 BP 5 EP 10 DI 10.1016/0143-4179(93)90035-9 PG 6 WC Endocrinology & Metabolism; Neurosciences SC Endocrinology & Metabolism; Neurosciences & Neurology GA KF173 UT WOS:A1993KF17300002 PM 7679211 ER PT S AU PATER, L YOUSEFI, R AF PATER, L YOUSEFI, R BE Hubbard, HH TI HANGARS AS NOISE BARRIERS FOR HELICOPTER NOISE SO NOISE-CON 93 PROCEEDINGS - 1993 NATIONAL CONFERENCE ON NOISE CONTROL ENGINEERING: NOISE CONTROL IN AEROACOUSTICS SE NOISE-CON PROCEEDINGS LA English DT Proceedings Paper CT 1993 National Conference on Noise Control Engineering: Noise Control in Aeroacoustics CY MAY 02-05, 1993 CL WILLIAMSBURG, VA SP NASA, LANGLEY RES CTR, INST NOISE CONTROL ENGN C1 USA,CONSTRUCT ENGN RES LABS,CHAMPAIGN,IL 61826. NR 0 TC 0 Z9 0 U1 0 U2 0 PU NOISE CONTROL FOUNDATION PI POUGHKEEPSIE PA PO BOX 2469, POUGHKEEPSIE, NY 12603 SN 0736-2935 BN 0-931784-26-3 J9 NOISE CON P PY 1993 BP 241 EP 246 PG 6 WC Acoustics; Engineering, Aerospace SC Acoustics; Engineering GA BB62Z UT WOS:A1993BB62Z00039 ER PT S AU FOLKES, PA AF FOLKES, PA BE Handel, PH Chung, AL TI FLUCTUATING DEEP-LEVEL TRAP OCCUPANCY MODEL FOR HOOGES 1/F NOISE PARAMETER FOR SEMICONDUCTOR RESISTORS SO NOISE IN PHYSICAL SYSTEMS AND 1/F FLUCTUATIONS SE AIP Conference Proceedings LA English DT Proceedings Paper CT INTERNATIONAL CONF ON NOISE IN PHYSICAL SYSTEMS AND 1/F FLUCTUATION ( ICNF 93 ) CY 1993 CL UNIV MISSOURI, ST LOUIS, MO HO UNIV MISSOURI C1 USA, RES LAB, FT MONMOUTH, NJ 07703 USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER INST PHYSICS PI MELVILLE PA 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA SN 0094-243X BN 1-56396-270-5 J9 AIP CONF PROC PY 1993 IS 285 BP 35 EP 38 PG 4 WC Physics, Applied; Physics, Condensed Matter SC Physics GA BZ02N UT WOS:A1993BZ02N00007 ER PT J AU CHACHO, EF AF CHACHO, EF TI SNOWMELT RUNOFF AND TOTAL SOLIDS PRODUCTION IN A DISCONTINUOUS PERMAFROST BASIN SO NORDIC HYDROLOGY LA English DT Article AB Snowmelt runoff and total suspended solids were measured for two years on Glenn Creek, a small, second-order, subarctic stream located near Fairbanks, Alaska, within the Yukon-Tanana Uplands physiographic province. The stream drains a 2.25-km2 research watershed of which 70 % is underlain by permafrost. The two years of study represent very different snowmelt hydrographs due to differences in the snowpacks. In 1985, the snowpack was 180 % of the long-term average, while in 1988 it was only 56 % of the average. During both years, 60 % of the total snowmelt-season water yield had passed before a significant rate of solids yield was observed. Also in both years the peak in total suspended solids concentration lagged the stream discharge peak by three days. Diurnal fluctuations in discharge and total suspended solids concentrations are well-defined, including a peculiar occurrence of double diurnal peaks in the discharge hydrograph during portions of the snowmelt season. The diurnal fluctuations in solids concentration are shown to be consistent with water temperature fluctuations. In 1988, the percentage of organics in the total suspended solids was scattered from 0 % to 66 % during the snowmelt season. RP CHACHO, EF (reprint author), USA, COLD REG RES & ENGN LAB, BLDG 4070, FT WAINWRIGHT, AK 99703 USA. NR 0 TC 1 Z9 1 U1 0 U2 0 PU IWA PUBLISHING PI LONDON PA ALLIANCE HOUSE, 12 CAXTON ST, LONDON SW1H0QS, ENGLAND SN 0029-1277 J9 NORD HYDROL JI Nord. Hydrol. PY 1993 VL 24 IS 2-3 BP 65 EP 78 PG 14 WC Water Resources SC Water Resources GA LM599 UT WOS:A1993LM59900002 ER PT J AU FERRICK, MG WEYRICK, PB NELSON, DF AF FERRICK, MG WEYRICK, PB NELSON, DF TI KINEMATIC MODEL OF RIVER ICE MOTION DURING DYNAMIC BREAKUP SO NORDIC HYDROLOGY LA English DT Article; Proceedings Paper CT 9TH INTERNATIONAL NORTHERN RESEARCH BASINS SYMP/WORKSHOP CY AUG, 1992 CL ENVIRONM CANADA, NATL HYDROL RES INST, SASKATOON, CANADA HO ENVIRONM CANADA, NATL HYDROL RES INST AB We begin a study of the dynamics of ice motion during river breakup by formulating a kinematic model. Ice continuity equations are applied to relate the speeds of a breaking front, a convergence front, a stoppage front, and a release front with the ice discharge and volume per unit surface area (unit volume) on either side of each front. Ice velocity was measured with time during a dynamic breakup at a pair of sites bounding a reach of the Connecticut River. We simulate the ice and front motion through time for this reach using the kinematic model with the assumptions that accumulation thickness and porosity are uniform, and that changes in the ice conditions and motion occur only at a front. Contrary to the basic assumption of static jam formation, we find that the accumulation developed while the ice was moving, and that jam formation merely represents the arrest of the motion. RP FERRICK, MG (reprint author), USA,COLD REG RES & ENGN LAB,HANOVER,NH 03755, USA. NR 0 TC 6 Z9 6 U1 0 U2 1 PU NORDISK ASSN HYDROLOGY PI DK LYNGBY PA TECHNICAL UNIV DENMARK BUILDING 115, 2800 DK LYNGBY, DENMARK SN 0029-1277 J9 NORD HYDROL JI Nord. Hydrol. PY 1993 VL 24 IS 2-3 BP 111 EP 134 PG 24 WC Water Resources SC Water Resources GA LM599 UT WOS:A1993LM59900005 ER PT J AU VANTUYLE, GJ TODOSOW, M GEIGER, MJ ARONSON, AL TAKAHASHI, H AF VANTUYLE, GJ TODOSOW, M GEIGER, MJ ARONSON, AL TAKAHASHI, H TI ACCELERATOR-DRIVEN SUBCRITICAL TARGET CONCEPT FOR TRANSMUTATION OF NUCLEAR WASTES SO NUCLEAR TECHNOLOGY LA English DT Article DE NUCLEAR WASTE TRANSMUTATION; ACCELERATOR DRIVEN; SUBCRITICAL TARGET LATTICE AB A means of transmuting key long-lived nuclear wastes, primarily the minor actinides (neptunium, americium, and curium) and iodine, using a hybrid proton accelerator and subcritical lattice, is proposed. By partitioning the components of the light water reactor (LWR) spent fuel and by transmuting key elements, such as the plutonium, the minor actinides, and a few of the long-lived fission products, some of the most significant challenges in building a waste repository can be substantially reduced. The proposed machine, based on the described PHOENIX Concept, would transmute the minor actinides and the iodine produced by 75 LWRs and would generate usable electricity (beyond that required to run the large accelerator) of 850 MW (electric). C1 US MIL ACAD,W POINT,NY 10997. RP VANTUYLE, GJ (reprint author), ASSOCIATED UNIV INC,BROOKHAVEN NATL LAB,DEPT NUCL ENERGY,BLDG 475B,UPTON,NY 11973, USA. NR 24 TC 26 Z9 26 U1 0 U2 0 PU AMER NUCLEAR SOCIETY PI LA GRANGE PK PA 555 N KENSINGTON AVENUE, LA GRANGE PK, IL 60525 SN 0029-5450 J9 NUCL TECHNOL JI Nucl. Technol. PD JAN PY 1993 VL 101 IS 1 BP 1 EP 17 PG 17 WC Nuclear Science & Technology SC Nuclear Science & Technology GA KD427 UT WOS:A1993KD42700001 ER PT J AU KING, N ODOM, TW SAMPSON, HW PARDUE, SL AF KING, N ODOM, TW SAMPSON, HW PARDUE, SL TI INOVO ADMINISTRATION OF BORON OR SODIUM ALUMINOSILICATE ALTERS MINERALIZATION IN THE TURKEY SO NUTRITION RESEARCH LA English DT Article DE BORON; ZEOLITE-A; INOVO; MINERALIZATION; TURKEY ID DIETARY BORON; ZEOLITE AB The potential of in ovo boron (B) or Na aluminosilicate (SA) administration to alter embryonic development and mineralization in the turkey was evaluated. At 15 d of embryogenesis, 150 mul of B (500 or 1000 ppm), SA (500 or 1000 ppm) or vehicle (8500 ppm NaCl) was injected into the air space of fertile turkey eggs (n=60/trt). At 26 d of embryogenesis and at hatch, random samples of blood and tibiae were obtained. In ovo administration of B or SA increased (P less-than-or-equal-to 0.05) embryonic weights, tibial length, and bone as h. Histological analysis of embryonic tibiae revealed a decrease (P less-than-or-equal-to 0.05) in growth plate length associated with B or SA administration. These data suggest that a single in ovo administration of boron or SA significantly influences embryonic growth and mineralization in the turkey. C1 TEXAS A&M UNIV SYST,DEPT POULTRY SCI,COLL STN,TX 77843. USA,ENVIRONM MED RES INST,NATICK,MA 01701. N CAROLINA STATE UNIV,DEPT POULTRY SCI,RALEIGH,NC 27695. TEXAS A&M UNIV SYST,DEPT ANAT,COLL STN,TX 77843. NR 27 TC 5 Z9 5 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0271-5317 J9 NUTR RES JI Nutr. Res. PD JAN PY 1993 VL 13 IS 1 BP 77 EP 85 DI 10.1016/S0271-5317(05)80658-X PG 9 WC Nutrition & Dietetics SC Nutrition & Dietetics GA KG560 UT WOS:A1993KG56000008 ER PT B AU SAWKA, MN WENGER, CB YOUNG, AJ PANDOLF, KB AF SAWKA, MN WENGER, CB YOUNG, AJ PANDOLF, KB BE Marriott, BM TI PHYSIOLOGICAL-RESPONSES TO EXERCISE IN THE HEAT SO NUTRITIONAL NEEDS IN HOT ENVIRONMENTS: APPLICATIONS FOR MILITARY PERSONNEL IN FIELD OPERATIONS LA English DT Proceedings Paper CT Workshop on Nutritional Needs in Hot Environments: Applications for Military Personnel in Field Operations CY APR 11-12, 1991 CL WASHINGTON, DC SP FOOD & NUTR BOARD, COMM MIL NUTR RES, NAT ACAD SCI, INST MED C1 USA,ENVIRONM MED RES INST,DIV THERMAL PHYSIOL & MED,NATICK,MA 01760. NR 0 TC 2 Z9 2 U1 0 U2 4 PU NATL ACADEMY PRESS PI WASHINGTON PA 2101 CONSTITUTION AVE NW, PO BOX 285, WASHINGTON, DC 20055 BN 0-309-04840-0 PY 1993 BP 55 EP 74 PG 20 WC Environmental Sciences; Medicine, Research & Experimental; Nutrition & Dietetics SC Environmental Sciences & Ecology; Research & Experimental Medicine; Nutrition & Dietetics GA BA83J UT WOS:A1993BA83J00003 ER PT B AU HIRSCH, ES KRAMER, FM AF HIRSCH, ES KRAMER, FM BE Marriott, BM TI SITUATIONAL INFLUENCES ON FOOD-INTAKE SO NUTRITIONAL NEEDS IN HOT ENVIRONMENTS: APPLICATIONS FOR MILITARY PERSONNEL IN FIELD OPERATIONS LA English DT Proceedings Paper CT Workshop on Nutritional Needs in Hot Environments: Applications for Military Personnel in Field Operations CY APR 11-12, 1991 CL WASHINGTON, DC SP FOOD & NUTR BOARD, COMM MIL NUTR RES, NAT ACAD SCI, INST MED C1 USA,NATICK LABS,NATICK,MA 01760. NR 0 TC 20 Z9 22 U1 1 U2 1 PU NATL ACADEMY PRESS PI WASHINGTON PA 2101 CONSTITUTION AVE NW, PO BOX 285, WASHINGTON, DC 20055 BN 0-309-04840-0 PY 1993 BP 215 EP 243 PG 29 WC Environmental Sciences; Medicine, Research & Experimental; Nutrition & Dietetics SC Environmental Sciences & Ecology; Research & Experimental Medicine; Nutrition & Dietetics GA BA83J UT WOS:A1993BA83J00011 ER PT B AU FRANCESCONI, RP ARMSTRONG, LE LEVA, NM MOORE, RJ SZLYK, PC MATTHEW, WT CURTIS, WC HUBBARD, RW ASKEW, EW AF FRANCESCONI, RP ARMSTRONG, LE LEVA, NM MOORE, RJ SZLYK, PC MATTHEW, WT CURTIS, WC HUBBARD, RW ASKEW, EW BE Marriott, BM TI ENDOCRINOLOGIC RESPONSES TO DIETARY SALT RESTRICTION DURING HEAT ACCLIMATION SO NUTRITIONAL NEEDS IN HOT ENVIRONMENTS: APPLICATIONS FOR MILITARY PERSONNEL IN FIELD OPERATIONS LA English DT Proceedings Paper CT Workshop on Nutritional Needs in Hot Environments: Applications for Military Personnel in Field Operations CY APR 11-12, 1991 CL WASHINGTON, DC SP FOOD & NUTR BOARD, COMM MIL NUTR RES, NAT ACAD SCI, INST MED C1 USA,ENVIRONM MED RES INST,DIV COMPARAT PHYSIOL,NATICK,MA 01760. NR 0 TC 4 Z9 4 U1 0 U2 0 PU NATL ACADEMY PRESS PI WASHINGTON PA 2101 CONSTITUTION AVE NW, PO BOX 285, WASHINGTON, DC 20055 BN 0-309-04840-0 PY 1993 BP 259 EP 275 PG 17 WC Environmental Sciences; Medicine, Research & Experimental; Nutrition & Dietetics SC Environmental Sciences & Ecology; Research & Experimental Medicine; Nutrition & Dietetics GA BA83J UT WOS:A1993BA83J00013 ER PT B AU JOHNSON, RF MERULLO, DJ AF JOHNSON, RF MERULLO, DJ BE Marriott, BM TI SUBJECTIVE REPORTS OF HEAT ILLNESS SO NUTRITIONAL NEEDS IN HOT ENVIRONMENTS: APPLICATIONS FOR MILITARY PERSONNEL IN FIELD OPERATIONS LA English DT Proceedings Paper CT Workshop on Nutritional Needs in Hot Environments: Applications for Military Personnel in Field Operations CY APR 11-12, 1991 CL WASHINGTON, DC SP FOOD & NUTR BOARD, COMM MIL NUTR RES, NAT ACAD SCI, INST MED C1 USA,ENVIRONM MED RES INST,DIV MIL PERFORMANCE & NEUROSCI,NATICK,MA 01760. NR 0 TC 5 Z9 5 U1 0 U2 0 PU NATL ACADEMY PRESS PI WASHINGTON PA 2101 CONSTITUTION AVE NW, PO BOX 285, WASHINGTON, DC 20055 BN 0-309-04840-0 PY 1993 BP 277 EP 293 PG 17 WC Environmental Sciences; Medicine, Research & Experimental; Nutrition & Dietetics SC Environmental Sciences & Ecology; Research & Experimental Medicine; Nutrition & Dietetics GA BA83J UT WOS:A1993BA83J00014 ER PT J AU ADAMS, MM READ, JA RAWLINGS, JS HARLASS, FB SARNO, AP RHODES, PH AF ADAMS, MM READ, JA RAWLINGS, JS HARLASS, FB SARNO, AP RHODES, PH TI PRETERM DELIVERY AMONG BLACK-AND-WHITE ENLISTED WOMEN IN THE UNITED-STATES-ARMY SO OBSTETRICS AND GYNECOLOGY LA English DT Article ID LOW-BIRTH-WEIGHT; PHYSICAL-ACTIVITY; RISK-FACTORS; PREGNANCY; POPULATION AB Objective: To examine black-white differences in preterm delivery in a healthy population who had unrestricted access to prenatal care. Methods: We conducted a retrospective cohort study of 842 black and 1026 white enlisted servicewomen who delivered a singleton infant of 20 or more weeks' gestation from July 1, 1987 through September 30, 1990 at four Army Medical Centers in the United States. Data were collected by reviewing maternal and newborn records. We used logistic and proportional hazards regression models to analyze outcomes defined by length of gestation, cause of preterm delivery, and jointly by length and cause. Results: Black enlisted women had a cumulative probability of preterm delivery (13.5%) that was higher than that for white enlisted women (10.5%) (hazard ratio 1.31, 95% confidence interval [CI] 1.002-1.70). However, the ratio of black-to-white hazards was not uniform. Black-white differences were small and nonsignificant from 33-36 weeks' gestation, when most preterm deliveries occur. The differences were also small and nonsignificant for deliveries related to spontaneous rupture of membranes or idiopathic preterm labor, the most common causes of preterm delivery. The black-to-white hazard ratios were greatest for all deliveries before 33 weeks' gestation and for medically indicated preterm deliveries. Conclusions: Efforts to reduce black-white differences in preterm delivery must go beyond providing prenatal care and eliminating recreational drug use. Future studies should consider black-white differences in environments during the mother's own development and in psychosocial and physical stresses during pregnancy. C1 CTR DIS CONTROL,NATL CTR PREVENT SERV,DIV IMMUNIZAT,ATLANTA,GA 30333. USA,DEPT OBSTET GYNECOL,TACOMA,WA. USA,MADIGAN ARMY MED CTR,DEPT PEDIAT,DIV NEWBORN MED,TACOMA,WA. TEXAS TECH ACAD HLTH CTR,DEPT OBSTET & GYNECOL,EL PASO,TX. TRIPLER ARMY MED CTR,DEPT OBSTET & GYNECOL,DIV MATERNAL FETAL MED,HONOLULU,HI 96859. RP ADAMS, MM (reprint author), NATL CTR CHRON DIS PREVENT & HLTH PROMOT,DIV REPROD HLTH,1600 CLIFTON RD K23,ATLANTA,GA 30333, USA. NR 26 TC 59 Z9 59 U1 2 U2 2 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0029-7844 J9 OBSTET GYNECOL JI Obstet. Gynecol. PD JAN PY 1993 VL 81 IS 1 BP 65 EP 71 PG 7 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA KE011 UT WOS:A1993KE01100013 PM 8416464 ER PT B AU KRISHFIELD, R HONJO, S TUCKER, WB NAKANISHI, T TAKIZAWA, T AF KRISHFIELD, R HONJO, S TUCKER, WB NAKANISHI, T TAKIZAWA, T GP IEEE TI AUTOMATED ICE-OCEAN ENVIRONMENTAL BUOYS (IOEBS) FOR THE TELEMETRY OF AIR, ICE AND OCEAN DATA FROM THE POLAR OCEANS SO OCEANS 93 - PROCEEDINGS, VOLS 1-3: ENGINEERING IN HARMONY WITH THE OCEAN LA English DT Proceedings Paper CT Oceans 93 - Engineering in Harmony with the Ocean CY OCT 18-21, 1993 CL VICTORIA, CANADA SP IEEE, OCEAN ENGN SOC C1 COLD REG RES & ENGN LAB,HANOVER,NH 03755. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-1385-2 PY 1993 BP B47 EP B52 PG 6 WC Engineering, Marine; Engineering, Electrical & Electronic SC Engineering GA BC53C UT WOS:A1993BC53C00012 ER PT J AU BAKER, WJ MAENPAA, JU WURZ, GT KOESTER, SK SEYMOUR, RC EMSHOFF, VD WIEBE, VJ DEGREGORIO, MW AF BAKER, WJ MAENPAA, JU WURZ, GT KOESTER, SK SEYMOUR, RC EMSHOFF, VD WIEBE, VJ DEGREGORIO, MW TI TOREMIFENE ENHANCES CELL-CYCLE BLOCK AND GROWTH-INHIBITION BY VINBLASTINE IN MULTIDRUG-RESISTANT HUMAN BREAST-CANCER CELLS SO ONCOLOGY RESEARCH LA English DT Article ID ACCUMULATION; REVERSAL AB The clinical study of compounds that modulate multidrug resistance has been hindered by both the toxicities of these agents and the inability to monitor their effectiveness at the level of the tumor cell. Previously, toremifene has been shown to be well tolerated clinically and to sensitize multidrug resistant cells to the effects of cytotoxic chemotherapeutic agents. The chemosensitizing properties of toremifene in estrogen receptor negative, multidrug resistant MDA-MB-A1 human breast cancer cells were studied using flow cytometric analysis and growth inhibition assays. Cell cycle kinetics of MDA-MB-A1 cells were not significantly affected by treatment with either toremifene, N-desmethyltoremifene, Toremifene IV or vinblastine alone, as the majority of cells remained in G0/G1. However, preincubation with toremifene or one of its metabolites for 72 hours followed by treatment for one hour with vinblastine caused a marked shift of cells to G2/M, as cells appeared to be blocked in that phase of the cell cycle. This result was nearly identical to the effect of vinblastine alone on vinblastine-sensitive MDA-MB-231 breast cancer cells and can be interpreted as a ''resensitization'' by toremifene of MDA-MB-A1 cells to vinblastine. This chemosensitizing effect of toremifene was accompanied by an enhanced inhibition of cell growth by vinblastine. The chemosensitizing effects of toremifene or one of its metabolites in combination with cytotoxic chemotherapy can be effectively monitored by flow cytometry, an easily accessible technique. C1 UNIV TEXAS,HLTH SCI CTR,SAN ANTONIO,TX 78284. UNIV TURKU,SF-20500 TURKU 50,FINLAND. RP BAKER, WJ (reprint author), BROOKE ARMY MED CTR,SAN ANTONIO,TX, USA. FU NCI NIH HHS [P50CA58183] NR 13 TC 7 Z9 7 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0965-0407 J9 ONCOL RES JI Oncol. Res. PY 1993 VL 5 IS 6-7 BP 207 EP 212 PG 6 WC Oncology SC Oncology GA MN494 UT WOS:A1993MN49400001 PM 8123940 ER PT J AU MAENPAA, JU WURZ, GT BAKER, WJ WIEBE, VJ EMSHOFF, VD KOESTER, SK SEYMOUR, RC KOEHLER, RE DEGREGORIO, MW AF MAENPAA, JU WURZ, GT BAKER, WJ WIEBE, VJ EMSHOFF, VD KOESTER, SK SEYMOUR, RC KOEHLER, RE DEGREGORIO, MW TI A BREAST-CANCER CLONE SELECTED BY TAMOXIFEN HAS INCREASED GROWTH-RATE AND REDUCED SENSITIVITY TO DOXORUBICIN SO ONCOLOGY RESEARCH LA English DT Article ID P-GLYCOPROTEIN; MULTIDRUG RESISTANCE; ATHYMIC MICE; CELLS; THERAPY; CHEMOTHERAPY; EXPRESSION; TUMORS; MODEL AB The in vivo growth rate and the chemosensitivity patterns of a cell clone selected by tamoxifen from the estrogen receptor-negative human breast cancer cell line MDA-MB-231 was studied in the nude mouse model and with flow cytometry. To investigate the growth rate of the wild-type and clone cells in vivo, the cells were inoculated into the opposite flanks of 5 male nude mice. Drug sensitivity to doxorubicin (10 ng/mL), vinblastine (1 ng/mL), and paclitaxel (1 ng/mL) was examined in wild-type/clone cell mixture using flow cytometry. Northern blot technique was used to study the expression of mdr-1 messenger RNA in both the wild-type and the clone cells. The tumors derived from the clone and wild-type cells were, following a 3-week growth period, 260.2 +/- 78.8 mm2 vs. 68.3 +/- 50.8 mm2 in size, respectively (P < 0.001). Following a 28-day continuous exposure, doxorubicin was selectively toxic to the wild-type cells, while having no apparent effect on the clone population. However, paclitaxel- and vinblastine-treated wild-type/clone cell mixtures did not exhibit a differential cytotoxic effect on either cell population. It was concluded that the clone selected by tamoxifen shows an aggressive growth rate in vivo and an altered chemosensitivity pattern to doxorubicin in vitro. C1 UTHSCSA,DEPT MED ONCOL,7703 FLOYD CURL,SAN ANTONIO,TX 78284. UNIV TURKU,DEPT OBSTET & GYNECOL,SF-20500 TURKU 50,FINLAND. BROOKE ARMY MED CTR,FT SAM HOUSTON,TX 78234. FU NCI NIH HHS [P50 CA598183, R01 CA30251] NR 28 TC 0 Z9 0 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0965-0407 J9 ONCOL RES JI Oncol. Res. PY 1993 VL 5 IS 12 BP 461 EP 466 PG 6 WC Oncology SC Oncology GA NP334 UT WOS:A1993NP33400001 PM 8086667 ER PT S AU RASZKA, WV ROBB, ML FOWLER, AK ROBERTS, CR WAECKER, NJ ASCHER, DP MORIARTY, RA GOLDBERG, D FISCHER, GW AF RASZKA, WV ROBB, ML FOWLER, AK ROBERTS, CR WAECKER, NJ ASCHER, DP MORIARTY, RA GOLDBERG, D FISCHER, GW BE Lyman, WD Rubinstein, A TI DIAGNOSIS AND QUANTITATION OF HIV-1 INFECTION IN INFANTS AND CHILDREN BY WHOLE-BLOOD CULTURE SO PEDIATRIC AIDS: CLINICAL, PATHOLOGIC, AND BASIC SCIENCE PERSPECTIVES SE ANNALS OF THE NEW YORK ACADEMY OF SCIENCES LA English DT Article; Proceedings Paper CT Conference on Pediatric Aids: Clinical, Pathologic, and Basic Science Perspectives CY NOV 18-21, 1992 CL WASHINGTON, DC SP NEW YORK ACAD SCI C1 WALTER REED ARMY INST RES, DEPT RETROVIRAL RES, ROCKVILLE, MD 20850 USA. UNIFORMED SERV UNIV HLTH SCI, DEPT PEDIAT, BETHESDA, MD 20814 USA. SRA LABS, ROCKVILLE, MD 20850 USA. USN, MED CTR, DEPT PEDIAT, SAN DIEGO, CA 92134 USA. WILFORD HALL USAF MED CTR, DEPT PEDIAT, SAN ANTONIO, TX 78236 USA. NATL NAVAL MED CTR, DEPT PEDIAT, BETHESDA, MD 20889 USA. NR 3 TC 2 Z9 2 U1 0 U2 0 PU NEW YORK ACAD SCIENCES PI NEW YORK PA 2 EAST 63RD ST, NEW YORK, NY 10021 SN 0077-8923 BN 0-89766-791-3 J9 ANN NY ACAD SCI JI Ann.NY Acad.Sci. PY 1993 VL 693 BP 258 EP 261 DI 10.1111/j.1749-6632.1993.tb26276.x PG 4 WC Immunology; Multidisciplinary Sciences; Pathology; Pediatrics; Virology SC Immunology; Science & Technology - Other Topics; Pathology; Pediatrics; Virology GA BZ45X UT WOS:A1993BZ45X00027 PM 8267272 ER PT J AU MOORE, JW LOVETT, EJ KIRBY, WC AF MOORE, JW LOVETT, EJ KIRBY, WC TI GASTROINTESTINAL HEMORRHAGE AFTER COMBINED PERCUTANEOUS ANGIOPLASTY OF AORTIC COARCTATION AND VALVULOPLASTY OF AORTIC-STENOSIS IN AN INFANT SO PEDIATRIC CARDIOLOGY LA English DT Article DE GASTROINTESTINAL HEMORRHAGE; ANGIOPLASTY; AORTIC COARCTATION; VALVULOPLASTY ID CONGENITAL-ANOMALIES REGISTRY; BALLOON ANGIOPLASTY; SURGICAL REPAIR AB Gastrointestinal hemorrhage has not been previously reported as a complication of dilating left-sided obstructive lesions. This report describes an infant who developed significant intestinal bleeding after combined angioplasty for aortic coarctation and valvuloplasty for aortic stenosis. C1 WALTER REED ARMY MED CTR,PEDIAT CARDIOL SECT,WASHINGTON,DC 20307. NR 7 TC 1 Z9 1 U1 0 U2 0 PU SPRINGER VERLAG PI NEW YORK PA 175 FIFTH AVE, NEW YORK, NY 10010 SN 0172-0643 J9 PEDIATR CARDIOL JI Pediatr. Cardiol. PD JAN PY 1993 VL 14 IS 1 BP 53 EP 55 PG 3 WC Cardiac & Cardiovascular Systems; Pediatrics SC Cardiovascular System & Cardiology; Pediatrics GA KB806 UT WOS:A1993KB80600014 PM 8456026 ER PT J AU ROSCELLI, JD AF ROSCELLI, JD TI AURAL, ORAL, OR RECTAL - DOES IT MAKE ANY REAL DIFFERENCE SO PEDIATRICS LA English DT Letter ID TYMPANIC MEMBRANE THERMOMETER; CHILDREN RP ROSCELLI, JD (reprint author), BROOKE ARMY MED CTR,DEPT PEDIAT,FT SAM HOUSTON,TX 78234, USA. NR 14 TC 0 Z9 0 U1 0 U2 0 PU AMER ACAD PEDIATRICS PI ELK GROVE VILLAGE PA 141 NORTH-WEST POINT BLVD, ELK GROVE VILLAGE, IL 60007-1098 SN 0031-4005 J9 PEDIATRICS JI Pediatrics PD JAN PY 1993 VL 91 IS 1 BP 166 EP 166 PG 1 WC Pediatrics SC Pediatrics GA KF835 UT WOS:A1993KF83500047 PM 8416495 ER PT J AU CLARK, L CUMMINGS, J BIRD, S ARONOV, E AF CLARK, L CUMMINGS, J BIRD, S ARONOV, E TI ACUTE TOXICITY OF THE BIRD REPELLENT, METHYL ANTHRANILATE, TO FRY OF SALMO-SALAR, ONCORHYNUS-MYKISS, ICTALURUS-PUNCTATUS AND LEPOMIS-MACROCHIRUS SO PESTICIDE SCIENCE LA English DT Article ID DIMETHYL ANTHRANILATE; CHEMICAL-STRUCTURE; LIVESTOCK FEED AB Several laboratory and field studies have shown methyl anthranilate to be an effective, non-toxic and non-lethal bird repellent, with application potential for protecting crops, seeds, turf and fish stocks from bird damage. Furthermore, methyl anthranilate can be added to liquids for the purposes of protecting migratory birds, e.g. addition to waste water associated with mining and to standing water pools at airports. Mammalian toxicity data are favorable. Methyl anthranilate is used as a fragrance and food flavoring and is GRAS listed by the US Food and Drug Administration. Despite the favorable outlook for methyl anthranilate's use as a safe repellent, no data exist on its environmental fate and effects. We have tested the acute toxicity of methyl anthranilate in a static system against the fry of four species of fish. The LC50 at 24 h for Atlantic salmon (Salmo salar L.) was 32.3 mg liter-1, with the no observable effect limit at 6 mg liter-1. The LC50 at 24 h for rainbow trout (Oncorhynus mykiss Richardson) was 23.5 mg liter-1, with the no observable effect limit at 5 mg liter-1. The LC50 at 24 h for channel catfish (Ictalurus punctatus Raf.) was estimated to be 20.1 mg liter-1, with the no observable effect limit at 7 mg liter-1. The LC50 at 24 h for bluegill sunfish (Lepomis macrochirus Raf.) was estimated to be 19.8 mg liter-1, with the no observable effect limit at 7 mg liter-1. C1 MONELL CHEM SENSES CTR,PHILADELPHIA,PA 19104. USA,CTR ENVIRONM,ABERDEEN PROVING GROUND,MD 21010. RP CLARK, L (reprint author), USDA,DENVER WILDLIFE RES CTR,DENVER FED CTR,ANIM PLANT HLTH INSPECT SERV,ANIM DAMAGE CONTROL,DENVER,CO 80225, USA. NR 25 TC 10 Z9 10 U1 0 U2 1 PU JOHN WILEY & SONS LTD PI W SUSSEX PA BAFFINS LANE CHICHESTER, W SUSSEX, ENGLAND PO19 1UD SN 0031-613X J9 PESTIC SCI JI Pestic. Sci. PY 1993 VL 39 IS 4 BP 313 EP 317 DI 10.1002/ps.2780390411 PG 5 WC Agronomy; Entomology SC Agriculture; Entomology GA MP340 UT WOS:A1993MP34000010 ER PT J AU FOX, AM HALLER, WT GETSINGER, KD AF FOX, AM HALLER, WT GETSINGER, KD TI CORRELATION OF ENDOTHAL AND FLUORESCENT DYE CONCENTRATIONS FOLLOWING CONCURRENT APPLICATION TO TIDAL CANALS SO PESTICIDE SCIENCE LA English DT Article ID AQUATIC HERBICIDE; FLURIDONE AB Herbicide residue samples are expensive and time-consuming to collect and analyze. The potential for using 'Rhodamine WT' to simulate endothal dissipation in moving water was tested in the weed-infested Three Sisters tidal canals (Citrus Co., FL). Concurrent applications were made using a variety of application techniques. Significant correlations between dye and endothal concentrations were found in each treatment, indicating that 'Rhodamine WT' concentrations can be used to predict endothal movement and concentrations. The ratios of endothal:dye half-lives were similar (0.2, 0.25, 0.17) for three of the application methods tested, indicating that estimations of dye half-lives could be used to predict those for endothal. C1 UNIV FLORIDA,DEPT AGRON,GAINESVILLE,FL 32606. USA,ENGINEER WATERWAYS EXPT STN,ENVIRONM LAB,VICKSBURG,MS 39180. RP FOX, AM (reprint author), UNIV FLORIDA,CTR AQUAT PLANTS,7922 NW 71ST ST,GAINESVILLE,FL 32606, USA. NR 15 TC 8 Z9 8 U1 0 U2 2 PU JOHN WILEY & SONS LTD PI W SUSSEX PA BAFFINS LANE CHICHESTER, W SUSSEX, ENGLAND PO19 1UD SN 0031-613X J9 PESTIC SCI JI Pestic. Sci. PY 1993 VL 37 IS 1 BP 99 EP 106 DI 10.1002/ps.2780370115 PG 8 WC Agronomy; Entomology SC Agriculture; Entomology GA LC222 UT WOS:A1993LC22200014 ER PT S AU STROSCIO, MA IAFRATE, GJ KIM, KW BHATT, AR DUTTA, M GRUBIN, HL AF STROSCIO, MA IAFRATE, GJ KIM, KW BHATT, AR DUTTA, M GRUBIN, HL BE Meissner, M Pohl, RO TI REDUCTION IN THE LONGITUDINAL-OPTICAL PHONON EMISSION RATE IN POLAR-SEMICONDUCTOR QUANTUM WIRES AND QUANTUM-WELLS SO PHONON SCATTERING IN CONDENSED MATTER VII: PROCEEDINGS OF THE SEVENTH INTERNATIONAL CONFERENCE SE SPRINGER SERIES IN SOLID-STATE SCIENCES LA English DT Proceedings Paper CT 7th International Conference on Phonon Scattering in Condensed Matter CY AUG 03-07, 1992 CL CORNELL UNIV, ITHACA, NY SP INT UNION PURE & APPL PHYS, NATL SCI FDN, USA RES OFF, USN OFF NAVAL RES, CORNELL UNIV, VICE PRESIDENT RES, CORNELL UNIV, MAT SCI CTR, CORNELL UNIV, PHYS DEP, CORNELL UNIV, LAB ATOM & SOLID STATE PHYS HO CORNELL UNIV C1 USA,RES OFF,RES TRIANGLE PK,NC 27709. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPRINGER-VERLAG BERLIN PI BERLIN 33 PA HEIDELBERGER PLATZ 3, W-1000 BERLIN 33, GERMANY SN 0171-1873 BN 3-540-56395-4 J9 SPRINGER SERIES SOLI PY 1993 VL 112 BP 341 EP 342 PG 2 WC Physics, Condensed Matter SC Physics GA BB68D UT WOS:A1993BB68D00135 ER PT J AU SCOVILL, JP THIGPEN, DL LEMLEY, PV AF SCOVILL, JP THIGPEN, DL LEMLEY, PV TI A CONVENIENT METHOD FOR THE SYNTHESIS AND RANEY-NICKEL DESULFURIZATION OF 5'-DEOXY-5'-METHYLTHIOADENOSINE SO PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS LA English DT Article DE 5'-DEOXYADENOSINE; 5'-DEOXY-5'-METHYLTHIOADENOSINE; 5'-CHLORO-5'-DEOXYADENOSINE; RANEY NICKEL DESULFURIZATION ID RICIN AB A convenient procedure for the preparation of 5'-deoxy-5'-methylthioadenosine is reported. Chlorination of adenosine with thionyl chloride yielded 5'-chloro-5'-deoxyadenosine. Reaction of 5'-chloro-5'-deoxyadenosine with aqueous methylmercaptide anion yielded 5'-deoxy-5'-methylthioadenosine. Hydrogenolysis of 5'-deoxy-5'-methylthioadenosine over Raney nickel in water produced 5'-deoxyadenosine. This procedure affords a high yield of readily purified 5'-deoxyadenosine while avoiding the use of anhydrous solvents and pyrophoric reagents. The procedure illustrates the utility of sulfur reagents to accomplish high value added transformations in nucleoside chemistry. RP SCOVILL, JP (reprint author), USA,MED RES INST INFECT DIS,DIV TOXINOL,FT DETRICK,MD 21702, USA. NR 7 TC 1 Z9 1 U1 1 U2 2 PU GORDON BREACH SCI PUBL LTD PI READING PA C/O STBS LTD PO BOX 90, READING, BERKS, ENGLAND RG1 8JL SN 0308-664X J9 PHOSPHORUS SULFUR JI Phosphorus Sulfur Silicon Relat. Elem. PY 1993 VL 85 IS 1-4 BP 149 EP 152 DI 10.1080/10426509308038193 PG 4 WC Chemistry, Inorganic & Nuclear; Chemistry, Organic SC Chemistry GA NG870 UT WOS:A1993NG87000019 ER PT J AU DONOVAN, WH FAMINI, GR JENSEN, JO AF DONOVAN, WH FAMINI, GR JENSEN, JO TI THEORETICAL PREDICTIONS OF THE STRUCTURE AND VIBRATIONAL INFRARED FREQUENCIES OF 2,2'-DICHLORODIETHYL SULFIDE AND HYDROLYSIS PRODUCTS SO PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS LA English DT Article DE SPECTRA; VIBRATIONAL; INFRARED; FREQUENCIES; INTENSITIES; SULFIDES ID ORGANO-PHOSPHORUS COMPOUNDS; QUANTITATIVE PREDICTION; MUSTARD DERIVATIVES; SULFUR MUSTARD; SPECTRA AB We report the computed equilibrium geometries and vibrational infrared frequencies for 2,2'-dichlorodiethyl sulfide and six related hydrolysis products, utilizing the HF/6-311G** and MP2/6-31G* levels of theory. A comparison of the calculated frequencies to the corresponding experimental data yields correction factors for the vibrational modes. In general, we find the use of larger basis sets tends to improve the consistency of the correction factors while inclusion of electron correlation tends to improve their accuracy. The agreement between the experimental and calculated data enables us to make predictions about the major features of the infrared spectra of the hydrolysis species for which no infrared data have been reported. C1 UNIV PENN,DEPT CHEM,PHILADELPHIA,PA 19104. RP DONOVAN, WH (reprint author), USA,EDGEWOOD RES DEV & ENGN CTR,SCBRD RTC,ABERDEEN PROVING GROUND,MD 21010, USA. NR 28 TC 12 Z9 12 U1 1 U2 2 PU GORDON BREACH SCI PUBL LTD PI READING PA C/O STBS LTD PO BOX 90, READING, BERKS, ENGLAND RG1 8JL SN 0308-664X J9 PHOSPHORUS SULFUR JI Phosphorus Sulfur Silicon Relat. Elem. PY 1993 VL 80 IS 1-4 BP 47 EP 61 DI 10.1080/10426509308036876 PG 15 WC Chemistry, Inorganic & Nuclear; Chemistry, Organic SC Chemistry GA MA892 UT WOS:A1993MA89200005 ER PT B AU KIRSCH, JC BAGLEY, H SLOAN, JA AF KIRSCH, JC BAGLEY, H SLOAN, JA BE Horner, JL Javidi, B Kowel, ST Miceli, WJ TI DUAL-CHANNEL SOLID BLOCK OPTICAL CORRELATOR SO PHOTONICS FOR PROCESSORS, NEURAL NETWORKS, AND MEMORIES SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Photonics for Processors, Neural Networks, and Memories CY JUL 12-15, 1993 CL SAN DIEGO, CA SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,MISSILE COMMAND,REDSTONE ARSENAL,AL 35898. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1275-9 J9 P SOC PHOTO-OPT INS PY 1993 VL 2026 BP 194 EP 202 DI 10.1117/12.163623 PG 9 WC Computer Science, Artificial Intelligence; Optics SC Computer Science; Optics GA BZ81K UT WOS:A1993BZ81K00020 ER PT B AU FRIDAY, WA HUDSON, TD KIRSCH, JC AF FRIDAY, WA HUDSON, TD KIRSCH, JC BE Horner, JL Javidi, B Kowel, ST Miceli, WJ TI OPTICAL-PROCESSING AT MICOM SO PHOTONICS FOR PROCESSORS, NEURAL NETWORKS, AND MEMORIES SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Photonics for Processors, Neural Networks, and Memories CY JUL 12-15, 1993 CL SAN DIEGO, CA SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,MISSILE COMMAND,WEAPONS SCI DIRECTORATE,REDSTONE ARSENAL,AL 35898. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1275-9 J9 P SOC PHOTO-OPT INS PY 1993 VL 2026 BP 250 EP 259 DI 10.1117/12.163578 PG 10 WC Computer Science, Artificial Intelligence; Optics SC Computer Science; Optics GA BZ81K UT WOS:A1993BZ81K00025 ER PT B AU CROWE, WM AF CROWE, WM BE Horner, JL Javidi, B Kowel, ST Miceli, WJ TI OPTICAL MORPHOLOGICAL PROCESSING OF OPTICAL CORRELATOR SIGNALS SO PHOTONICS FOR PROCESSORS, NEURAL NETWORKS, AND MEMORIES SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Photonics for Processors, Neural Networks, and Memories CY JUL 12-15, 1993 CL SAN DIEGO, CA SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,MISSILE COMMAND,WEAPONS SCI DIRECTORATE,AMSMI RD WS PO,REDSTONE ARSENAL,AL 35898. NR 0 TC 1 Z9 1 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1275-9 J9 P SOC PHOTO-OPT INS PY 1993 VL 2026 BP 297 EP 301 DI 10.1117/12.163582 PG 5 WC Computer Science, Artificial Intelligence; Optics SC Computer Science; Optics GA BZ81K UT WOS:A1993BZ81K00030 ER PT B AU WICKMAN, HA AYVAZIAN, AM HICKEY, CF AF WICKMAN, HA AYVAZIAN, AM HICKEY, CF BE Taylor, KA Thompson, SW Fletcher, FB TI EVALUATION OF AN ARMY STEEL PRODUCED BY THE AC DQ PROCESS SO PHYSICAL METALLURGY OF DIRECT-QUENCHED STEELS LA English DT Proceedings Paper CT Symposium on Physical Metallurgy of Direct-Quenched Steels CY NOV 02-04, 1992 CL CHICAGO, IL SP MINERALS MET & MAT SOC, FERROUS MET COMM, AMER SOC MET INT, PHASE TRANSFORMAT COMM C1 USA,RES LAB,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MINERALS, METALS & MATERIALS SOC PI WARRENDALE PA 420 COMMONWEALTH DR, WARRENDALE, PA 15086 BN 0-87339-212-4 PY 1993 BP 423 EP 444 PG 22 GA BZ40K UT WOS:A1993BZ40K00023 ER PT J AU LI, Y KRIEGER, JB IAFRATE, GJ AF LI, Y KRIEGER, JB IAFRATE, GJ TI SELF-CONSISTENT CALCULATIONS OF ATOMIC PROPERTIES USING SELF-INTERACTION-FREE EXCHANGE-ONLY KOHN-SHAM POTENTIALS SO PHYSICAL REVIEW A LA English DT Article ID DENSITY-FUNCTIONAL THEORY; DERIVATIVE DISCONTINUITIES; ENERGY-BANDS AB The spin-unrestricted optimized-effective-potential (OEP) method and an approximation to it due to the authors (KLI) have been applied to atoms from Li (Z = 3) to Ba (Z = 56) plus Au (Z = 79) and Hg (Z = 80) within the exchange-only scheme. Calculations were performed for the term with the lowest energy in the ground-state configuration. For a few transition elements, terms in the low-lying excited-energy-state configuration are also self-consistently calculated. We have compared our OEP and KLI results with each other and with those obtained from the spin-unrestricted Hartree-Fock (SUHF) method and the local-spin-density exchange-only (LSDX) approximation. As the spin-restricted OEP, the spin-unrestricted OEP yields nearly identical results as the corresponding SUHF. The relative difference of the total energy from that of the SUHF is only 40 ppm for 3Li and monotonically decreases as Z increases to less than 2 ppm for 80Hg. The highest occupied energy eigenvalues of each spin projection, E(m sigma), and the various expectation values for the operators r2, r-1, and delta(r) are all very similar to the SUHF theory. For most of the atoms, even the spin density mimics the SUHF value quite well. Differences appear to be larger for some transition- and noble-metal atoms. Nevertheless, even in these cases, the total energy and the total electron density of the OEP calculations are still very similar to the corresponding SUHF values. For atoms with the highest occupied energy eigenvalues having the same spatial quantum numbers for both spin projections, the spin splitting, epsilon(m down) - epsilon(m up), corresponding to the difference between the highest occupied eigenvalues of the minority (down) and majority (up) spin states, is also studied. It is found that the OEP and SUHF spin splittings are nearly identical for atoms with the highest occupied eigenstate being a p state. Noticeable differences (of the OEP and HF spin splitting) occur for a few transition elements having an empty (n - 1)d down subshell. However, such larger differences are steadily diminished as the (n - 1)d down subshell is progressively filled. As an approximate Kohn-Sham (KS) potential, the KLI method shows itself to be a much improved one compared to the LSDX. The exchange potential constructed from this method retains many of the essential properties of the exact OEP that the LSDX approximation lacks and thus always yields better densities, lower total energies, and mom accurate. eigenvalues for the highest occupied energy state of each spin projection than the LSDX approximation. In particular, the total energies overestimate the OEP results by only 9 ppm for Li, with the overestimate decreasing for increasing atomic number Z to less than 1 ppm for Z > 50. In addition, for atoms other than transition elements or noble metals, the epsilon(m sigma) are within 0.4% of the corresponding OEP results with slightly larger differences for the other atoms. In all cases, the KLI results for the expectation values r2, r-1 and the density at the origin are very close to the exact KS results and are a significant improvement over those provided by the LSDX approximation. C1 USA, RES OFF, RES TRIANGLE PK, NC 27709 USA. RP CUNY BROOKLYN COLL, DEPT PHYS, BROOKLYN, NY 11210 USA. NR 33 TC 161 Z9 161 U1 0 U2 6 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 2469-9926 EI 2469-9934 J9 PHYS REV A JI Phys. Rev. A PD JAN PY 1993 VL 47 IS 1 BP 165 EP 181 DI 10.1103/PhysRevA.47.165 PG 17 WC Optics; Physics, Atomic, Molecular & Chemical SC Optics; Physics GA KG725 UT WOS:A1993KG72500031 ER PT B AU POINDEXTER, EH SAKS, NS SCHULZ, M STROSCIO, MA AF POINDEXTER, EH SAKS, NS SCHULZ, M STROSCIO, MA BE Helms, CR Deal, BE TI DEFECTS AND HOT-CARRIER-INDUCED DAMAGE IN SI-SIO2 SYSTEMS - INTRODUCTION SO PHYSICS AND CHEMISTRY OF SIO2 AND THE SI-SI0-2 INTERFACE 2 LA English DT Proceedings Paper CT 2nd Symposium on the Physics and Chemistry of the SIO-2 and SI-SIO-2 Interface, at the 181st Meeting of the Electrochemical-Society CY MAY 18-22, 1992 CL ST LOUIS, MO SP ELECTROCHEM SOC, ELECTR & DIELECTR SCI & TECHNOL DIV C1 USA,ELECTR TECHNOL & DEVICES LAB,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU PLENUM PRESS DIV PLENUM PUBLISHING CORP PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 BN 0-306-44419-4 PY 1993 BP 371 EP 372 PG 2 WC Electrochemistry; Physics, Applied; Physics, Condensed Matter SC Electrochemistry; Physics GA BZ43Y UT WOS:A1993BZ43Y00046 ER PT B AU SMITH, CR AF SMITH, CR BE Grandy, WT Milonni, PW TI ON RADAR TARGET IDENTIFICATION SO PHYSICS AND PROBABILITY: ESSAYS IN HONOR OF EDWIN T. JAYNES LA English DT Proceedings Paper CT Symposium on Physics and Probability CY MAY 15-16, 1992 CL UNIV WYOMING, LARAMIE, WY SP UNIV WYOMING, DEPT PHYS & ASTRON HO UNIV WYOMING C1 USA,MISSILE COMMAND,CTR RES DEV & ENGN,ADV SENSORS DIRECTORATE,REDSTONE ARSENAL,AL 35898. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CAMBRIDGE UNIV PRESS PI CAMBRIDGE PA THE PITT BUILDING, TRUMPINGTON ST, CAMBRIDGE, CAMBS, ENGLAND CB2 1RP BN 0-521-43471-8 PY 1993 BP 161 EP 175 DI 10.1017/CBO9780511524448.017 PG 15 WC Mechanics; Optics; Physics, Mathematical SC Mechanics; Optics; Physics GA BA06K UT WOS:A1993BA06K00016 ER PT J AU WADE, WL MAMMONE, RJ BINDER, M AF WADE, WL MAMMONE, RJ BINDER, M TI INCREASED DIELECTRIC-BREAKDOWN STRENGTHS OF MELT-EXTRUDED POLYPROPYLENE FILMS SO POLYMER LA English DT Note DE POLYPROPYLENE FILM; DIELECTRIC BREAKDOWN STRENGTH; MELT EXTRUSION AB Melt-extruded polypropylene resin containing 1% or 2% ceresine wax yielded thin films that had significantly increased dielectric breakdown strengths but with virtually identical bulk dielectric properties. Ceresine wax acts as a trapping centre for electrons and by minimizing ionization of host polypropylene molecules, dielectric breakdown strength is increased. C1 USA,RES LAB,ENERGY SCI BRANCH,FT MONMOUTH,NJ 07703. NR 5 TC 5 Z9 5 U1 0 U2 4 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB SN 0032-3861 J9 POLYMER JI Polymer PY 1993 VL 34 IS 5 BP 1093 EP 1094 DI 10.1016/0032-3861(93)90234-2 PG 2 WC Polymer Science SC Polymer Science GA KQ526 UT WOS:A1993KQ52600027 ER PT B AU MATTICE, MS AF MATTICE, MS GP AMER AUTOMAT CONTROL COUNCIL TI A NONLINEAR FLEXIBLE POINTING SYSTEM FOR DIGITAL-CONTROL RESEARCH SO PROCEEDINGS OF THE 1993 AMERICAN CONTROL CONFERENCE, VOLS 1-3 LA English DT Proceedings Paper CT 1993 AMERICAN CONTROL CONF CY JUN 02-04, 1993 CL SAN FRANCISCO, CA SP INT FEDERAT AUTOMAT CONTROL, AMER INST AERONAUT & ASTRONAUT, AMER INST CHEM ENGINEERS, ASSOC IRON & STEEL ENGINEERS, AMER SOC MECH ENGINEERS, IEEE, INSTRUMENT SOC AMER, SOC COMP SIMULAT RP MATTICE, MS (reprint author), USA,ARMAMENT RES,CTR DEV & ENGN,BLDG 95 N,PICATINNY ARSENAL,NJ 07806, USA. NR 0 TC 3 Z9 3 U1 0 U2 0 PU I E E E PI NEW YORK PA NEW YORK BN 0-7803-0860-3 PY 1993 BP 526 EP 530 PG 5 WC Engineering, Electrical & Electronic SC Engineering GA BY87D UT WOS:A1993BY87D00124 ER PT B AU MCCULLOUGH, CL AF MCCULLOUGH, CL GP AMER AUTOMAT CONTROL COUNCIL TI INTELLIGENT CONTROLLERS WHICH CAN ADAPT TO CHANGING ENVIRONMENTS - ANTICIPATORY NEURO-FUZZY CONTROL SO PROCEEDINGS OF THE 1993 AMERICAN CONTROL CONFERENCE, VOLS 1-3 LA English DT Proceedings Paper CT 1993 AMERICAN CONTROL CONF CY JUN 02-04, 1993 CL SAN FRANCISCO, CA SP INT FEDERAT AUTOMAT CONTROL, AMER INST AERONAUT & ASTRONAUT, AMER INST CHEM ENGINEERS, ASSOC IRON & STEEL ENGINEERS, AMER SOC MECH ENGINEERS, IEEE, INSTRUMENT SOC AMER, SOC COMP SIMULAT RP MCCULLOUGH, CL (reprint author), USA,SPACE & STRATEG DEF COMMAND,POB 1500,HUNTSVILLE,AL, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA NEW YORK BN 0-7803-0860-3 PY 1993 BP 1865 EP 1869 PG 5 WC Engineering, Electrical & Electronic SC Engineering GA BY87D UT WOS:A1993BY87D00412 ER PT B AU POPE, J STEWART, CJ NAIRN, RB AF POPE, J STEWART, CJ NAIRN, RB GP CANADIAN COASTAL SCIENCE & ENGN ASSOC TI IMPACTS OF GREAT-LAKES - ST-LAWRENCE-RIVER WATER-LEVEL FLUCTUATIONS ON RECESSION RATES AND COASTAL PROCESSES SO PROCEEDINGS OF THE 1993 CANADIAN COASTAL CONFERENCE, VOLS 1 AND 2 LA English DT Proceedings Paper CT 1993 Canadian Coastal Conference CY MAY 04-07, 1993 CL VANCOUVER, CANADA SP CANADIAN COASTAL SCI & ENGN ASSOC, SIMON FRASER UNIV C1 USA,WATERWAYS EXPT STN,COASTAL ENGN RES CTR,VICKSBURG,MS 39180. NR 0 TC 0 Z9 0 U1 0 U2 0 PU NATL RESEARCH COUNCIL CANADA COASTAL ZONE ENGN PROGRAM PI OTTAWA PA BUILDING M-32, MONTREAL ROAD, OTTAWA ON K1A 0R6, CANADA PY 1993 BP 151 EP 166 PG 16 WC Ecology; Engineering, Marine; Environmental Sciences; Marine & Freshwater Biology SC Environmental Sciences & Ecology; Engineering; Marine & Freshwater Biology GA BB05H UT WOS:A1993BB05H00012 ER PT B AU PARCHURE, TM LONG, BF AF PARCHURE, TM LONG, BF GP CANADIAN COASTAL SCIENCE & ENGN ASSOC TI EROSIONAL AND DEPOSITIONAL PROPERTIES OF RUPERT BAY SEDIMENT SO PROCEEDINGS OF THE 1993 CANADIAN COASTAL CONFERENCE, VOLS 1 AND 2 LA English DT Proceedings Paper CT 1993 Canadian Coastal Conference CY MAY 04-07, 1993 CL VANCOUVER, CANADA SP CANADIAN COASTAL SCI & ENGN ASSOC, SIMON FRASER UNIV C1 WATERWAYS EXPT STN,VICKSBURGE,MS 39180. NR 0 TC 0 Z9 0 U1 0 U2 0 PU NATL RESEARCH COUNCIL CANADA COASTAL ZONE ENGN PROGRAM PI OTTAWA PA BUILDING M-32, MONTREAL ROAD, OTTAWA ON K1A 0R6, CANADA PY 1993 BP 685 EP 697 PG 13 WC Ecology; Engineering, Marine; Environmental Sciences; Marine & Freshwater Biology SC Environmental Sciences & Ecology; Engineering; Marine & Freshwater Biology GA BB05H UT WOS:A1993BB05H00051 ER PT B AU KOSINSKI, JA BALLATO, A LU, YC AF KOSINSKI, JA BALLATO, A LU, YC GP IEEE TI PURE-MODE MEASUREMENTS OF DILITHIUM TETRABORATE MATERIAL PROPERTIES SO PROCEEDINGS OF THE 1993 IEEE INTERNATIONAL FREQUENCY CONTROL SYMPOSIUM LA English DT Proceedings Paper CT 1993 IEEE International Frequency Control Symposium (the 47th Annual Symposium) CY JUN 02-04, 1993 CL SALT LAKE CITY, UT SP IEEE, ULTRASPM FERROELECT & FREQUENCY CONTROL SOC C1 USA,RES LAB,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-0905-7 PY 1993 BP 359 EP 370 PG 12 WC Engineering, Electrical & Electronic SC Engineering GA BZ86X UT WOS:A1993BZ86X00051 ER PT B AU HENDRICKSON, M LAFFEY, S VIG, JR AF HENDRICKSON, M LAFFEY, S VIG, JR GP IEEE TI INVESTIGATIONS OF GOLD-FILMS ON QUARTZ CRYSTALS SO PROCEEDINGS OF THE 1993 IEEE INTERNATIONAL FREQUENCY CONTROL SYMPOSIUM LA English DT Proceedings Paper CT 1993 IEEE International Frequency Control Symposium (the 47th Annual Symposium) CY JUN 02-04, 1993 CL SALT LAKE CITY, UT SP IEEE, ULTRASPM FERROELECT & FREQUENCY CONTROL SOC C1 USA,RES LAB,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-0905-7 PY 1993 BP 574 EP 581 PG 8 WC Engineering, Electrical & Electronic SC Engineering GA BZ86X UT WOS:A1993BZ86X00076 ER PT B AU MIZAN, M HIGGINS, T STURZEBECHER, D AF MIZAN, M HIGGINS, T STURZEBECHER, D GP IEEE TI PHASE NOISE AND FREQUENCY STABILITY OF KA-BAND HARMONIC DIELECTRIC RESONATOR OSCILLATORS SO PROCEEDINGS OF THE 1993 IEEE INTERNATIONAL FREQUENCY CONTROL SYMPOSIUM LA English DT Proceedings Paper CT 1993 IEEE International Frequency Control Symposium (the 47th Annual Symposium) CY JUN 02-04, 1993 CL SALT LAKE CITY, UT SP IEEE, ULTRASPM FERROELECT & FREQUENCY CONTROL SOC C1 USA,RES LAB,FT MONMOUTH,NJ 07703. NR 0 TC 6 Z9 6 U1 0 U2 0 PU I E E E PI NEW YORK PA 345 E 47TH ST, NEW YORK, NY 10017 BN 0-7803-0905-7 PY 1993 BP 733 EP 739 PG 7 WC Engineering, Electrical & Electronic SC Engineering GA BZ86X UT WOS:A1993BZ86X00101 ER PT S AU TURNER, DA ZEID, AA OVERHOLT, J AF TURNER, DA ZEID, AA OVERHOLT, J BE Schoen, J TI IMPLEMENTATION OF AN EXPLICIT MULTIBODY DYNAMICS METHOD ON THE MASSIVELY-PARALLEL CONNECTION MACHINE CM-5 SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 USA,HIGH PERFORMANCE COMP RES CTR,COMP SCI CORP,WARREN,MI 48397. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 326 EP 332 PG 7 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00057 ER PT S AU ROCHE, EC HANESIAN, D LIU, YL AF ROCHE, EC HANESIAN, D LIU, YL BE Schoen, J TI REMOVAL OF VOCS FROM A CONTAMINATED AIR STREAM SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 US MIL ACAD,W POINT,NY 10996. NR 0 TC 0 Z9 0 U1 0 U2 1 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 364 EP 367 PG 4 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00064 ER PT S AU KIM, KC AF KIM, KC BE Schoen, J TI HELICOPTER TRIM CALCULATION IN FORWARD FLIGHT SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 USA,RES LAB,SURVIVABIL LETHAL ANAL DIRECTORATE,DIV BALLIST VULNERABIL LETHAL,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 374 EP 379 PG 6 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00066 ER PT S AU SCHRAML, SJ COLEMAN, MW AF SCHRAML, SJ COLEMAN, MW BE Schoen, J TI IMPLEMENTATION OF A MESSAGE-PASSING SCHEME IN AN EXPLICIT FINITE-DIFFERENCE CFD ALGORITHM SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 USA,RES LAB,ABERDEEN PROVING GROUND,MD 21010. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 391 EP 396 PG 6 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00069 ER PT S AU BUNDY, ML GERBER, N BRADLEY, JW AF BUNDY, ML GERBER, N BRADLEY, JW BE Schoen, J TI GUN BARREL EROSION AND BORE TEMPERATURE MODELING SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 USA,WEAP TECHNOL DIRECTORATE,DIV PROPULS & FLIGHT,WASHINGTON,DC 20310. NR 0 TC 1 Z9 2 U1 0 U2 1 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 397 EP 402 PG 6 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00070 ER PT S AU GUPTA, AD WISNIEWSKI, HL AF GUPTA, AD WISNIEWSKI, HL BE Schoen, J TI 3-DIMENSIONAL FINITE-ELEMENT MODEL GENERATION OF AN ARMORED VEHICLE FOR RESPONSE SIMULATION SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 USA,RES LAB,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 403 EP 408 PG 6 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00071 ER PT S AU KUNKEL, RW BURDESHAW, MD AF KUNKEL, RW BURDESHAW, MD BE Schoen, J TI DEGRADED STATES VULNERABILITY ANALYSIS OF AIRCRAFT SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 USA,RES LAB,AMSRL SL BA,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 409 EP 412 PG 4 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00072 ER PT S AU HADUCH, TW GILBERT, A AF HADUCH, TW GILBERT, A BE Schoen, J TI SIMULATION AND MODELING OF ROBOTIC VEHICLES ON THE BATTLEFIELD SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 USA,RES LAB,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 1 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 419 EP 424 PG 6 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00074 ER PT S AU ZEID, AA OVERHOLT, JL AF ZEID, AA OVERHOLT, JL BE Schoen, J TI AUTOMATING CONCEPT GENERATION AND DESIGN OF DYNAMIC-SYSTEMS SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 USA,HIGH PERFORMANCE COMP RES CTR,COMP SCI CORP,WARREN,MI 48090. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 435 EP 440 PG 6 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00077 ER PT S AU GROFF, JN PRENATT, RE ROTH, TE AF GROFF, JN PRENATT, RE ROTH, TE BE Schoen, J TI SPACE 3 METRICS - DEGRADED STATES SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 USA,RES LAB,ABERDEEN PROVING GROUND,MD 21005. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 447 EP 452 PG 6 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00079 ER PT S AU COLE, JS REYNOLDS, TM AF COLE, JS REYNOLDS, TM BE Schoen, J TI SEEKSIM - A MILLIMETER-WAVE SEEKER SIMULATION SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 HWIL SIMULAT,SYST SIMULAT & DEV DIRECTORATE,CTR RES DEV & ENGN,REDSTONE ARSENAL,AL 35898. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 652 EP 657 PG 6 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00112 ER PT S AU SHOLES, WJ AF SHOLES, WJ BE Schoen, J TI USING REFLECTIVE MEMORY IN A REAL-TIME HARDWARE-IN-THE-LOOP CONTROL INPUT-OUTPUT SYSTEM SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 HWIL SIMULAT BRANCH,SYST SIMULAT & DEV DIRECTORATE,CTR RES DEV & ENGN,REDSTONE ARSENAL,AL 35898. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 664 EP 669 PG 6 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00114 ER PT S AU MULLINS, JH TERRILL, SD HARRISON, KR LEOPARD, PH AF MULLINS, JH TERRILL, SD HARRISON, KR LEOPARD, PH BE Schoen, J TI A DETERMINISTIC MILLIMETER-WAVE SENSOR MODEL FOR TERMINALLY GUIDED SUBMUNITIONS SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 USA,CTR RES DEV & ENGN,ADV SENSORS DIRECTORATE,REDSTONE ARSENAL,AL 35898. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 711 EP 716 PG 6 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00121 ER PT S AU MOLNAR, J AF MOLNAR, J BE Schoen, J TI THE TERRAIN PREPARATION SYSTEM SO PROCEEDINGS OF THE 1993 SUMMER COMPUTER SIMULATION CONFERENCE SE PROCEEDINGS OF THE SUMMER COMPUTER SIMULATION CONFERENCE LA English DT Proceedings Paper CT 25th Annual Summer Computer Simulation Conference CY JUL 19-21, 1993 CL BOSTON, MA SP SOC COMP SIMULAT C1 USA,CTR JOINT WARFARE,HURLBURT FIELD,FL. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SOC COMPUTER SIMULATION INT PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92177 SN 0094-7474 BN 1-56555-057-9 J9 P SUMM COMP PY 1993 BP 882 EP 886 PG 5 WC Computer Science, Interdisciplinary Applications; Multidisciplinary Sciences SC Computer Science; Science & Technology - Other Topics GA BA23R UT WOS:A1993BA23R00148 ER PT B AU CHRISTOPHER, HA GILMAN, S HAMLEN, RP AF CHRISTOPHER, HA GILMAN, S HAMLEN, RP GP CALIF STATE UNIV, DEPT ELECT ENGN TI UNITED-STATES ARMY RESEARCH LABORATORY POWER SOURCES R&D PROGRAMS SO PROCEEDINGS OF THE EIGHTH ANNUAL BATTERY CONFERENCE ON APPLICATIONS AND ADVANCES LA English DT Proceedings Paper CT 8th Annual Battery Conference on Applications and Advances CY JAN 12-14, 1993 CL LONG BEACH, CA SP CALIF STATE UNIV, DEPT ELECT ENGN, CALIF INST TECHNOL, JET PROPULS LAB, ELECTROCHEM SOC INC, SO CALIF NEVADA SECT, AIAA, SAN GABRIEL VALLEY SECT, IEEE, ORANGE CTY SECT, INFOTECHNICS INC, CORDLESS POWER NEWS & POWER TECHNOL NEWS, SO CALIF EDISON CO, DEPT WATER & POWER, LOS ANGELES, LIEBERT CORP, INT BATTERY TECHNOL, BATTERY LINE C1 ELECTR & POWER SOURCES DIRECTORATE,ARMY RES LAB,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CALIFORNIA STATE UNIV CONSORTIUM PI LONG BEACH PA 1250 BELLFLOWER BLVD, LONG BEACH, CA 90840 PY 1993 BP 39 EP 44 PG 6 WC Electrochemistry; Energy & Fuels SC Electrochemistry; Energy & Fuels GA BC66F UT WOS:A1993BC66F00006 ER PT J AU TASCHEK, WG JACOBS, R AF TASCHEK, WG JACOBS, R GP CALIF STATE UNIV, DEPT ELECT ENGN TI SILENT ENERGY SOURCE FOR TACTICAL APPLICATIONS SO PROCEEDINGS OF THE EIGHTH ANNUAL BATTERY CONFERENCE ON APPLICATIONS AND ADVANCES LA English DT Proceedings Paper CT 8th Annual Battery Conference on Applications and Advances CY JAN 12-14, 1993 CL LONG BEACH, CA SP CALIF STATE UNIV, DEPT ELECT ENGN, CALIF INST TECHNOL, JET PROPULS LAB, ELECTROCHEM SOC INC, SO CALIF NEVADA SECT, AIAA, SAN GABRIEL VALLEY SECT, IEEE, ORANGE CTY SECT, INFOTECHNICS INC, CORDLESS POWER NEWS & POWER TECHNOL NEWS, SO CALIF EDISON CO, DEPT WATER & POWER, LOS ANGELES, LIEBERT CORP, INT BATTERY TECHNOL, BATTERY LINE C1 USA,BELVOIR RES,CTR DEV & ENGN,FT BELVOIR,VA 22060. NR 0 TC 0 Z9 0 U1 0 U2 0 PU CALIFORNIA STATE UNIV CONSORTIUM PI LONG BEACH PA 1250 BELLFLOWER BLVD, LONG BEACH, CA 90840 PY 1993 BP 91 EP 95 PG 5 WC Electrochemistry; Energy & Fuels SC Electrochemistry; Energy & Fuels GA BC66F UT WOS:A1993BC66F00013 ER PT B AU SCHAUDIES, RP AF SCHAUDIES, RP BE DeNovo, R TI EPIDERMAL GROWTH-FACTOR SO PROCEEDINGS OF THE ELEVENTH ANNUAL VETERINARY MEDICAL FORUM LA English DT Proceedings Paper CT 11th Annual Veterinary Medical Forum CY 1993 CL WASHINGTON, DC SP AMER COLL VET INTERNAL MEDHILLS PET NUTR INC, HILLS PET NUTR INC, MERCK RES LABS, WALTHAM, SMITHKLINE BEECHAM ANIM HLTH, UPJOHN, CIBA GEIGY, VET RES ASSOC, RALSTON PURINA C1 WALTER REED ARMY INST RES,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER COLL VETERINARY INTERNAL MEDICINE PI LAKEWOOD PA 7175 W JEFFERSON AVE STE 2125, LAKEWOOD, CO 80235 PY 1993 BP 80 EP 81 PG 2 WC Veterinary Sciences SC Veterinary Sciences GA BA40A UT WOS:A1993BA40A00020 ER PT J AU BERG, B AF BERG, B BE Wayman, CM Perkins, J TI THE DYNAMICS OF THE SIMPLE PULLEY SMA HEAT ENGINE SO PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON MARTENSITIC TRANSFORMATIONS (ICOMAT-92) LA English DT Proceedings Paper CT International Conference on Martensitic Transformations (ICOMAT-92) CY JUL 20-24, 1992 CL MONTEREY, CA SP MONTEREY INST ADV STUDIES C1 UNIV MINNESOTA,USA,HIGH PERFORMANCE COMP RES CTR,DEPT AEROSP ENGN & MECH,MINNEAPOLIS,MN 55455. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MONTEREY INST ADVANCED STUDIES PI CARMEL PA PO BOX 4427, CARMEL, CA 93921 PY 1993 BP 1277 EP 1282 PG 6 WC Metallurgy & Metallurgical Engineering; Materials Science, Characterization & Testing; Physics, Condensed Matter SC Metallurgy & Metallurgical Engineering; Materials Science; Physics GA BD05K UT WOS:A1993BD05K00203 ER PT B AU AUSTIN, AS FRODGE, SL PLECITY, M DENDY, RP AF AUSTIN, AS FRODGE, SL PLECITY, M DENDY, RP GP INST NAVIGAT TI THE ADVANCED COMMUNICATIONS TECHNOLOGY SATELLITE FOR A DIFFERENTIAL GLOBAL POSITIONING SYSTEM SO PROCEEDINGS OF THE NATIONAL TECHNICAL MEETING OF THE INSTITUTE OF NAVIGATION: EVOLUTION THROUGH INTEGRATION OF CURRENT AND EMERGING SYSTEMS LA English DT Proceedings Paper CT National Technical Meeting of the Institute-of-Navigation on Evolution Through Integration of Current and Emerging Systems CY JAN 20-22, 1993 CL SAN FRANCISCO, CA SP INST NAVIGAT C1 USA,CTR TOPOG ENGINEER,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU INST NAVIGATION PI WASHINGTON PA 815 15TH ST NW, STE 832, WASHINGTON, DC 20005 PY 1993 BP 389 EP 397 PG 9 WC Engineering, Aerospace; Transportation SC Engineering; Transportation GA BA73Z UT WOS:A1993BA73Z00039 ER PT J AU HALPHEN, LP AF HALPHEN, LP GP INST NAVIGAT TI THE COORDINATED IMPLEMENTATION OF A DIFFERENTIAL GLOBAL POSITIONING SYSTEM ALONG THE LOWER MISSISSIPPI RIVER SO PROCEEDINGS OF THE NATIONAL TECHNICAL MEETING OF THE INSTITUTE OF NAVIGATION: EVOLUTION THROUGH INTEGRATION OF CURRENT AND EMERGING SYSTEMS LA English DT Proceedings Paper CT National Technical Meeting of the Institute-of-Navigation on Evolution Through Integration of Current and Emerging Systems CY JAN 20-22, 1993 CL SAN FRANCISCO, CA SP INST NAVIGAT C1 USA,CORPS ENGINEER,NEW ORLEANS,LA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU INST NAVIGATION PI WASHINGTON PA 815 15TH ST NW, STE 832, WASHINGTON, DC 20005 PY 1993 BP 509 EP 518 PG 10 WC Engineering, Aerospace; Transportation SC Engineering; Transportation GA BA73Z UT WOS:A1993BA73Z00052 ER PT B AU HEMPEN, GL AF HEMPEN, GL GP INT SOC OF EXPLOS ENGINEERS TI REDUCING UNDERWATER BLAST DAMAGE WITH AIR-SCREENS SO PROCEEDINGS OF THE NINETEENTH ANNUAL CONFERENCE ON EXPLOSIVES AND BLASTING TECHNIQUE LA English DT Proceedings Paper CT 19th Annual Conference on Explosives and Blasting Technique CY JAN 31-FEB 04, 1993 CL SAN DIEGO, CA SP INT SOC EXPLOS ENGINEERS C1 USA,CORPS ENGINEERS,ST LOUIS DIST,ST LOUIS,MO. NR 0 TC 0 Z9 0 U1 0 U2 0 PU INT SOC EXPLOSIVES ENGINEERS PI CLEVELAND PA 29100 AURORA ROAD, CLEVELAND, OH 44139-1800 PY 1993 BP 337 EP 346 PG 10 WC Engineering, Multidisciplinary; Engineering, Civil SC Engineering GA BA16W UT WOS:A1993BA16W00030 ER PT B AU CALKINS, DJ AF CALKINS, DJ BE Ferrick, M Pangburn, T TI GROUNDWATER TEMPERATURES DURING THE WINTER IN A FORESTED BASIN SO PROCEEDINGS OF THE SIXTY-FIRST ANNUAL WESTERN SNOW CONFERENCE LA English DT Proceedings Paper CT 61st Annual Western Snow Conference/50th Annual Eastern Snow Conference CY JUN 08-10, 1993 CL QUEBEC CITY, CANADA C1 USA,COLD REG RES & ENGN LAB,GEOL SCI BRANCH,HANOVER,NH 03755. NR 0 TC 0 Z9 0 U1 0 U2 0 PU 61ST WESTERN SNOW CONFERENCE PI QUEBEC PA QUEBEC QUEBEC, CANADA PY 1993 BP 19 EP 23 PG 5 WC Meteorology & Atmospheric Sciences; Water Resources SC Meteorology & Atmospheric Sciences; Water Resources GA BA96Z UT WOS:A1993BA96Z00003 ER PT B AU GATTO, LW AF GATTO, LW BE Ferrick, M Pangburn, T TI RIVER ICE CONDITIONS DETERMINED FROM ERS-1 SAR SO PROCEEDINGS OF THE SIXTY-FIRST ANNUAL WESTERN SNOW CONFERENCE LA English DT Proceedings Paper CT 61st Annual Western Snow Conference/50th Annual Eastern Snow Conference CY JUN 08-10, 1993 CL QUEBEC CITY, CANADA C1 USA,COLD REG RES & ENGN LAB,GEOL SCI BRANCH,HANOVER,NH 03755. NR 0 TC 1 Z9 1 U1 0 U2 0 PU 61ST WESTERN SNOW CONFERENCE PI QUEBEC PA QUEBEC QUEBEC, CANADA PY 1993 BP 113 EP 122 PG 10 WC Meteorology & Atmospheric Sciences; Water Resources SC Meteorology & Atmospheric Sciences; Water Resources GA BA96Z UT WOS:A1993BA96Z00015 ER PT B AU KOH, G AF KOH, G BE Ferrick, M Pangburn, T TI FMCW RADAR INVESTIGATION OF SNOW PACK EVOLUTION SO PROCEEDINGS OF THE SIXTY-FIRST ANNUAL WESTERN SNOW CONFERENCE LA English DT Proceedings Paper CT 61st Annual Western Snow Conference/50th Annual Eastern Snow Conference CY JUN 08-10, 1993 CL QUEBEC CITY, CANADA C1 USA,COLD REG RES & ENGN LAB,GEOPHYS SCI BRANCH,HANOVER,NH 03755. NR 0 TC 0 Z9 0 U1 0 U2 0 PU 61ST WESTERN SNOW CONFERENCE PI QUEBEC PA QUEBEC QUEBEC, CANADA PY 1993 BP 123 EP 127 PG 5 WC Meteorology & Atmospheric Sciences; Water Resources SC Meteorology & Atmospheric Sciences; Water Resources GA BA96Z UT WOS:A1993BA96Z00016 ER PT B AU HAEHNEL, RB WILKINSON, JH LEVER, JH AF HAEHNEL, RB WILKINSON, JH LEVER, JH BE Ferrick, M Pangburn, T TI SNOWDRIFT MODELING IN THE CRREL WIND-TUNNEL SO PROCEEDINGS OF THE SIXTY-FIRST ANNUAL WESTERN SNOW CONFERENCE LA English DT Proceedings Paper CT 61st Annual Western Snow Conference/50th Annual Eastern Snow Conference CY JUN 08-10, 1993 CL QUEBEC CITY, CANADA C1 USA,COLD REG RES & ENGN LAB,ICE ENGN RES BRANCH,HANOVER,NH 03755. NR 0 TC 2 Z9 3 U1 0 U2 0 PU 61ST WESTERN SNOW CONFERENCE PI QUEBEC PA QUEBEC QUEBEC, CANADA PY 1993 BP 139 EP 147 PG 9 WC Meteorology & Atmospheric Sciences; Water Resources SC Meteorology & Atmospheric Sciences; Water Resources GA BA96Z UT WOS:A1993BA96Z00018 ER PT B AU HARDY, JP ALBERT, DG AF HARDY, JP ALBERT, DG BE Ferrick, M Pangburn, T TI THE PERMEABILITY OF TEMPERATE SNOW - PRELIMINARY LINKS TO MICROSTRUCTURE SO PROCEEDINGS OF THE SIXTY-FIRST ANNUAL WESTERN SNOW CONFERENCE LA English DT Proceedings Paper CT 61st Annual Western Snow Conference/50th Annual Eastern Snow Conference CY JUN 08-10, 1993 CL QUEBEC CITY, CANADA C1 USA,COLD REG RES & ENGN LAB,GEOL SCI BRANCH,HANOVER,NH 03755. NR 0 TC 4 Z9 4 U1 0 U2 0 PU 61ST WESTERN SNOW CONFERENCE PI QUEBEC PA QUEBEC QUEBEC, CANADA PY 1993 BP 149 EP 156 PG 8 WC Meteorology & Atmospheric Sciences; Water Resources SC Meteorology & Atmospheric Sciences; Water Resources GA BA96Z UT WOS:A1993BA96Z00019 ER PT B AU DAVIS, RE ELDER, K ROSENTHAL, W MELACK, J SICKMAN, J AF DAVIS, RE ELDER, K ROSENTHAL, W MELACK, J SICKMAN, J BE Ferrick, M Pangburn, T TI ESTIMATING TOTAL SNOW VOLUME IN A SMALL ALPINE WATERSHED USING REMOTELY-SENSED DATA AND GROUND-BASED SURVEYS SO PROCEEDINGS OF THE SIXTY-FIRST ANNUAL WESTERN SNOW CONFERENCE LA English DT Proceedings Paper CT 61st Annual Western Snow Conference/50th Annual Eastern Snow Conference CY JUN 08-10, 1993 CL QUEBEC CITY, CANADA C1 USA,COLD REG RES & ENGN LAB,GEOPHYS SCI BRANCH,HANOVER,NH 03755. NR 0 TC 0 Z9 0 U1 0 U2 0 PU 61ST WESTERN SNOW CONFERENCE PI QUEBEC PA QUEBEC QUEBEC, CANADA PY 1993 BP 197 EP 203 PG 7 WC Meteorology & Atmospheric Sciences; Water Resources SC Meteorology & Atmospheric Sciences; Water Resources GA BA96Z UT WOS:A1993BA96Z00025 ER PT B AU ALBERT, MR HARDY, JP AF ALBERT, MR HARDY, JP BE Ferrick, M Pangburn, T TI SNOWPACK STRATIGRAPHY EVOLUTION AT FORESTED AND OPEN SITES SO PROCEEDINGS OF THE SIXTY-FIRST ANNUAL WESTERN SNOW CONFERENCE LA English DT Proceedings Paper CT 61st Annual Western Snow Conference/50th Annual Eastern Snow Conference CY JUN 08-10, 1993 CL QUEBEC CITY, CANADA C1 USA,COLD REG RES & ENGN LAB,GEOL SCI BRANCH,HANOVER,NH 03755. NR 0 TC 5 Z9 5 U1 0 U2 0 PU 61ST WESTERN SNOW CONFERENCE PI QUEBEC PA QUEBEC QUEBEC, CANADA PY 1993 BP 205 EP 212 PG 8 WC Meteorology & Atmospheric Sciences; Water Resources SC Meteorology & Atmospheric Sciences; Water Resources GA BA96Z UT WOS:A1993BA96Z00026 ER PT B AU HOGAN, A FERRICK, M AF HOGAN, A FERRICK, M BE Ferrick, M Pangburn, T TI EXAMINING THE INFLUENCE OF SNOW COVER ON MORNING AIR-TEMPERATURE SO PROCEEDINGS OF THE SIXTY-FIRST ANNUAL WESTERN SNOW CONFERENCE LA English DT Proceedings Paper CT 61st Annual Western Snow Conference/50th Annual Eastern Snow Conference CY JUN 08-10, 1993 CL QUEBEC CITY, CANADA C1 USA,COLD REG RES & ENGN LAB,GEOCHEM SCI BRANCH,HANOVER,NH 03755. NR 0 TC 0 Z9 0 U1 0 U2 0 PU 61ST WESTERN SNOW CONFERENCE PI QUEBEC PA QUEBEC QUEBEC, CANADA PY 1993 BP 223 EP 229 PG 7 WC Meteorology & Atmospheric Sciences; Water Resources SC Meteorology & Atmospheric Sciences; Water Resources GA BA96Z UT WOS:A1993BA96Z00028 ER PT B AU CRAGIN, JH HEWITT, AD AF CRAGIN, JH HEWITT, AD BE Ferrick, M Pangburn, T TI AEROSOL SCAVENGING BY FALLING SNOW SO PROCEEDINGS OF THE SIXTY-FIRST ANNUAL WESTERN SNOW CONFERENCE LA English DT Proceedings Paper CT 61st Annual Western Snow Conference/50th Annual Eastern Snow Conference CY JUN 08-10, 1993 CL QUEBEC CITY, CANADA C1 USA,COLD REG RES & ENGN LAB,SNOW & ICE BRANCH,HANOVER,NH 03755. NR 0 TC 1 Z9 1 U1 1 U2 1 PU 61ST WESTERN SNOW CONFERENCE PI QUEBEC PA QUEBEC QUEBEC, CANADA PY 1993 BP 307 EP 314 PG 8 WC Meteorology & Atmospheric Sciences; Water Resources SC Meteorology & Atmospheric Sciences; Water Resources GA BA96Z UT WOS:A1993BA96Z00038 ER PT B AU SODHI, DS RAND, JH TOBIASSON, W AF SODHI, DS RAND, JH TOBIASSON, W BE Ferrick, M Pangburn, T TI STRESS-ANALYSIS OF A PROPOSED TUNNEL UNDER THE SOUTH-POLE SKIWAY SO PROCEEDINGS OF THE SIXTY-FIRST ANNUAL WESTERN SNOW CONFERENCE LA English DT Proceedings Paper CT 61st Annual Western Snow Conference/50th Annual Eastern Snow Conference CY JUN 08-10, 1993 CL QUEBEC CITY, CANADA C1 USA,COLD REG RES & ENGN LAB,ICE ENGN RES BRANCH,HANOVER,NH 03755. NR 0 TC 1 Z9 1 U1 0 U2 0 PU 61ST WESTERN SNOW CONFERENCE PI QUEBEC PA QUEBEC QUEBEC, CANADA PY 1993 BP 347 EP 354 PG 8 WC Meteorology & Atmospheric Sciences; Water Resources SC Meteorology & Atmospheric Sciences; Water Resources GA BA96Z UT WOS:A1993BA96Z00043 ER PT B AU BATES, RE FIORI, JE FISK, DJ HARRINGTON, BG AF BATES, RE FIORI, JE FISK, DJ HARRINGTON, BG BE Ferrick, M Pangburn, T TI MESOSCALE ATMOSPHERE ICING EVENT, MARCH 1991 SO PROCEEDINGS OF THE SIXTY-FIRST ANNUAL WESTERN SNOW CONFERENCE LA English DT Proceedings Paper CT 61st Annual Western Snow Conference/50th Annual Eastern Snow Conference CY JUN 08-10, 1993 CL QUEBEC CITY, CANADA C1 USA,COLD REG RES & ENGN LAB,GEOPHYS SCI BRANCH,HANOVER,NH 03755. NR 0 TC 0 Z9 0 U1 0 U2 0 PU 61ST WESTERN SNOW CONFERENCE PI QUEBEC PA QUEBEC QUEBEC, CANADA PY 1993 BP 355 EP 364 PG 10 WC Meteorology & Atmospheric Sciences; Water Resources SC Meteorology & Atmospheric Sciences; Water Resources GA BA96Z UT WOS:A1993BA96Z00044 ER PT B AU FLICKINGER, WH FITZPATRICK, K WELCH, SL AF FLICKINGER, WH FITZPATRICK, K WELCH, SL BE Sumanth, DJ Edosomwan, JA Poupart, R Sink, DS TI HOW ARE AGENCIES TO RESPOND TO INCREASING DEMANDS FOR SERVICES AND DECREASING RESOURCES SO PRODUCTIVITY & QUALITY MANAGEMENT FRONTIERS IV, VOLS 1 AND 2 LA English DT Proceedings Paper CT 4th International Conference on Productivity and Quality Research CY FEB 09-12, 1993 CL MIAMI, FL SP UNIV MIAMI, DEPT IND ENGN, PROD RES GRP, UNIV MIAMI, SCH CONTINUING STUDIES, OFF CONF & INST, INST IND ENGINEERS DE DECREASING RESOURCES; FACILITIES; PERSONNEL ISSUES; PRODUCTIVITY; PROGRAMS; PUBLIC AGENCIES; RESOURCES; SERVICES C1 USA,CONSTRUCT ENG RES LAB,CHAMPAIGN,IL. NR 0 TC 0 Z9 0 U1 0 U2 0 PU INDUSTRIAL ENGINEERING & MANAGEMENT PR PI NORCROSS PA 25 TECHNOLOGY PARK, NORCROSS, GA 30092 BN 0-89806-125-3 PY 1993 BP 697 EP 705 PG 9 WC Management SC Business & Economics GA BA39R UT WOS:A1993BA39R00097 ER PT B AU TOMLINSON, DW BROWN, G AF TOMLINSON, DW BROWN, G BE Sumanth, DJ Edosomwan, JA Poupart, R Sink, DS TI OVERCOMING RESISTANCE TO TQM IN A GOVERNMENT RESEARCH LABORATORY SO PRODUCTIVITY & QUALITY MANAGEMENT FRONTIERS IV, VOLS 1 AND 2 LA English DT Proceedings Paper CT 4th International Conference on Productivity and Quality Research CY FEB 09-12, 1993 CL MIAMI, FL SP UNIV MIAMI, DEPT IND ENGN, PROD RES GRP, UNIV MIAMI, SCH CONTINUING STUDIES, OFF CONF & INST, INST IND ENGINEERS C1 USA CERL FST,CHAMPAIGN,IL. NR 0 TC 0 Z9 0 U1 0 U2 0 PU INDUSTRIAL ENGINEERING & MANAGEMENT PR PI NORCROSS PA 25 TECHNOLOGY PARK, NORCROSS, GA 30092 BN 0-89806-125-3 PY 1993 BP 1064 EP 1064 PG 1 WC Management SC Business & Economics GA BA39R UT WOS:A1993BA39R00151 ER PT B AU FARRELL, S AF FARRELL, S BE Sumanth, DJ Edosomwan, JA Poupart, R Sink, DS TI STUMBLE THE MUMBLE - A NECESSARY STEP BEFORE WALKING THE TALK OF QUALITY INITIATIVES SO PRODUCTIVITY & QUALITY MANAGEMENT FRONTIERS IV, VOLS 1 AND 2 LA English DT Proceedings Paper CT 4th International Conference on Productivity and Quality Research CY FEB 09-12, 1993 CL MIAMI, FL SP UNIV MIAMI, DEPT IND ENGN, PROD RES GRP, UNIV MIAMI, SCH CONTINUING STUDIES, OFF CONF & INST, INST IND ENGINEERS C1 USA CONSTRUCT ENGN RES LABS,CHAMPAIGN,IL. NR 0 TC 0 Z9 0 U1 0 U2 0 PU INDUSTRIAL ENGINEERING & MANAGEMENT PR PI NORCROSS PA 25 TECHNOLOGY PARK, NORCROSS, GA 30092 BN 0-89806-125-3 PY 1993 BP 1255 EP 1255 PG 1 WC Management SC Business & Economics GA BA39R UT WOS:A1993BA39R00184 ER PT B AU CHURCH, EL TAKACS, PZ AF CHURCH, EL TAKACS, PZ BE Bilbro, JW Parks, RE TI SURFACE SPECIFICATION IN TERMS OF SYSTEM PERFORMANCE SO QUALITY AND RELIABILITY FOR OPTICAL SYSTEMS SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Quality and Reliability for Optical Systems CY JUL 11-12, 1993 CL SAN DIEGO, CA SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,ARDEC,DOVER,NJ 07801. NR 0 TC 2 Z9 2 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1242-2 J9 P SOC PHOTO-OPT INS PY 1993 VL 1993 BP 54 EP 64 DI 10.1117/12.164986 PG 11 WC Optics SC Optics GA BZ89G UT WOS:A1993BZ89G00007 ER PT B AU KORNFELD, G PENN, J AF KORNFELD, G PENN, J BE Chavez, PS Schowengerdt, RA TI VARIOUS FLIR SENSOR EFFECTS APPLIED TO SYNTHETIC THERMAL IMAGERY SO RECENT ADVANCES IN SENSORS, RADIOMETRIC CALIBRATION, AND PROCESSING OF REMOTELY SENSED DATA SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT Conference on Recent Advances in Sensors, Radiometric Calibration, and Processing of Remotely Sensed Data CY APR 14-16, 1993 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS C1 USA,RES LAB,FT BELVOIR,VA 22060. NR 0 TC 1 Z9 1 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA PO BOX 10, BELLINGHAM, WA 98227-0010 BN 0-8194-1174-4 J9 P SOC PHOTO-OPT INS PY 1993 VL 1938 BP 350 EP 366 DI 10.1117/12.161560 PG 17 WC Optics SC Optics GA BZ57A UT WOS:A1993BZ57A00035 ER PT B AU BOWDEN, CM AF BOWDEN, CM BE Inguva, R TI NEAR DIPOLE-DIPOLE INTERACTION EFFECTS IN QUANTUM AND NONLINEAR OPTICS SO RECENT DEVELOPMENTS IN QUANTUM OPTICS LA English DT Proceedings Paper CT International Conference on Coherence and Quantum Optics CY JAN 05-10, 1991 CL UNIV HYDERABAD, HYDERABAD, INDIA SP UNIV HYDERABAD, SCH PHYS HO UNIV HYDERABAD C1 USA,MISSILE COMMAND,CTR RES DEV & ENGN,WEAP SCI DIRECTORATE,AMSMI RD WS,REDSTONE ARSENAL,AL 35898. NR 0 TC 1 Z9 1 U1 0 U2 0 PU PLENUM PRESS DIV PLENUM PUBLISHING CORP PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 BN 0-306-44403-8 PY 1993 BP 55 EP 63 PG 9 WC Optics; Physics, Applied SC Optics; Physics GA BZ51K UT WOS:A1993BZ51K00007 ER PT B AU SINGH, S BOWDEN, CM AF SINGH, S BOWDEN, CM BE Inguva, R TI NEW RESONANCES IN 4-WAVE-MIXING DUE TO VELOCITY CHANGING COLLISIONS SO RECENT DEVELOPMENTS IN QUANTUM OPTICS LA English DT Proceedings Paper CT International Conference on Coherence and Quantum Optics CY JAN 05-10, 1991 CL UNIV HYDERABAD, HYDERABAD, INDIA SP UNIV HYDERABAD, SCH PHYS HO UNIV HYDERABAD C1 USA,MISSILE COMMAND,CTR RES DEV & ENGN,WEAP SCI DIRECTORATE,AMSMI RD WS,REDSTONE ARSENAL,AL 35898. NR 0 TC 0 Z9 0 U1 0 U2 0 PU PLENUM PRESS DIV PLENUM PUBLISHING CORP PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 BN 0-306-44403-8 PY 1993 BP 553 EP 556 PG 4 WC Optics; Physics, Applied SC Optics; Physics GA BZ51K UT WOS:A1993BZ51K00069 ER PT J AU ATKINS, JL YUAN, C CHEN, SW PAMNANI, M AF ATKINS, JL YUAN, C CHEN, SW PAMNANI, M TI RENAL LYMPHATIC OBSTRUCTION IN DIABETIC RATS INDUCES SYSTEMIC HYPOTENSION SO RENAL FAILURE LA English DT Article AB We obstructed renal lymph drainage from a single kidney in diabetic rats who had received 65 mg/kg streptozotocin 6 months prior to the study Lymphatic obstruction led to a progressive fall in systematic blood pressure from a mean arterial pressure of 101 +/- 5 (SEM) mm Hg (n = 7) to 62 +/- 4 mm Hg (n = 5) (p < .02) after 1.5 h. No change was seen in a sham-operated animal. Despite the decline in systemic blood pressure there was no significant change in the GFR of either kidney. Sodium excretion increased significantly in the experimental kidney There was no change in the urinary excretion of cyclic GMP from either kidney, and plasma levels of atrial natriuretic peptide (ANP) did not change (55 +/- 21 pg/mL pre- to 64 +/- 18 postobstruction). The results are consistent with a systemic vasodilatation after lymphatic obstruction. The mechanism of this response is still under investigation, but apparently it does not involve ANP. RP ATKINS, JL (reprint author), WALTER REED ARMY INST RES,DEPT NEPHROL,BLDG 40,ROOM 3035,WASHINGTON,DC 20307, USA. RI Atkins, James/B-3577-2011 NR 0 TC 0 Z9 0 U1 0 U2 0 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0886-022X J9 RENAL FAILURE JI Ren. Fail. PY 1993 VL 15 IS 1 BP 33 EP 36 DI 10.3109/08860229309065569 PG 4 WC Urology & Nephrology SC Urology & Nephrology GA KK620 UT WOS:A1993KK62000005 PM 8441834 ER PT J AU GHIORSE, SR AF GHIORSE, SR TI EFFECT OF VOID CONTENT ON THE MECHANICAL-PROPERTIES OF CARBON EPOXY LAMINATES SO SAMPE QUARTERLY-SOCIETY FOR THE ADVANCEMENT OF MATERIAL AND PROCESS ENGINEERING LA English DT Article ID COMPOSITE AB A series of (0/90)4s laminates with varying void content were fabricated. Two quasistatic mechanical tests, short beam shear and three-point flexure, were used for evaluation and the results correlated to void volume fraction. Accurately quantifying the strength fall off proved difficult. Values of strength drop-off recorded were: 9.7% per percent void for interlaminar shear, 10.3% per percent void for flexural strength, and 5.3% per percent void for flexural modulus. In a manufacturing setting, a 2% void content increase will cause an approximate 20% decrease in both interlaminar shear strength and flexural strength, accompanied by an approximate 10% drop in flexural modulus. Void content has been shown to be a major consideration in composite materials' quality control, regardless of the loading mode. RP GHIORSE, SR (reprint author), USA,RES LAB,WATERTOWN,MA 02172, USA. NR 18 TC 67 Z9 77 U1 2 U2 19 PU SAMPE PUBLISHERS PI COVINA PA 1161 PARKVIEW DRIVE, COVINA, CA 91722 SN 0036-0821 J9 SAMPE QUART PD JAN PY 1993 VL 24 IS 2 BP 54 EP 59 PG 6 WC Engineering, Multidisciplinary; Materials Science, Multidisciplinary SC Engineering; Materials Science GA KJ703 UT WOS:A1993KJ70300008 ER PT B AU HINTON, YL AF HINTON, YL BE Vary, A TI APPLICATION OF PATTERN-RECOGNITION TECHNIQUES TO ACOUSTOULTRASONIC TESTING OF KEVLAR(TM) COMPOSITE PANELS SO SECOND INTERNATIONAL CONFERENCE ON ACOUSTO-ULTRASONICS: ACOUSTO-ULTRASONIC MATERIALS CHARACTERIZATION LA English DT Proceedings Paper CT 2nd International Conference on Acousto-Ultrasonics: Acousto-Ultrasonic Materials Characterization CY JUN 24-25, 1993 CL ATLANTA, GA SP AMER SOC NONDESTRUCT TESTING INC C1 USA,RES LAB,VEHICLE STRUCT DIRECTORATE,WATERTOWN,MA 02172. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER SOC NONDESTRUCTIVE TESTING PI COLUMBUS PA 1711 ARLINGATE LANE, PO BOX 28518, COLUMBUS, OH 43228-0518 BN 0-931403-20-0 PY 1993 BP 125 EP 132 PG 8 WC Acoustics; Materials Science, Characterization & Testing SC Acoustics; Materials Science GA BA75R UT WOS:A1993BA75R00014 ER PT S AU THURAISINGHAM, B RUBINOVITZ, H FOTI, D ABREU, A AF THURAISINGHAM, B RUBINOVITZ, H FOTI, D ABREU, A GP IEEE, COMP SOC TI DESIGN AND IMPLEMENTATION OF A DISTRIBUTED DATABASE INFERENCE CONTROLLER SO SEVENTEENTH ANNUAL INTERNATIONAL COMPUTER SOFTWARE & APPLICATIONS CONFERENCE SE PROCEEDINGS - INTERNATIONAL COMPUTER SOFTWARE & APPLICATIONS CONFERENCE LA English DT Proceedings Paper CT 17th Annual International Computer Software and Applications Conference (Compsac 93) CY NOV 01-05, 1993 CL PHOENIX, AZ SP IEEE, COMP SOC C1 USA,CECOM,FT MONMOUTH,NJ 07703. NR 0 TC 0 Z9 0 U1 0 U2 0 PU I E E E, COMPUTER SOC PRESS PI LOS ALAMITOS PA 10662 LOS VAQUEROS CIRCLE, LOS ALAMITOS, CA 90720 SN 0730-3157 BN 0-8186-4440-0 J9 P INT COMP SOFTW APP PY 1993 BP 152 EP 158 DI 10.1109/CMPSAC.1993.404229 PG 7 WC Computer Science, Software Engineering; Engineering, Electrical & Electronic SC Computer Science; Engineering GA BA39E UT WOS:A1993BA39E00023 ER PT J AU AVERICK, BM ORTEGA, JM AF AVERICK, BM ORTEGA, JM TI FAST SOLUTION OF NONLINEAR POISSON-TYPE EQUATIONS SO SIAM JOURNAL ON SCIENTIFIC COMPUTING LA English DT Article DE POISSON EQUATION; NONLINEAR EQUATIONS; PARALLEL AB For certain nonlinear Poisson-type equations, it is possible to make a change of variable so that the solution is obtained by solving a Poisson equation followed by solving one-dimensional nonlinear equations. For those problems for which a Fast Poisson Solver may be used, this method is considerably faster than methods that solve a discretization of the original equation by Newton-type methods. Moreover, there is excellent parallelism in the solution of the one-dimensional equations. Numerical results are given for some model problems on a CRAY-2 and comparisons are made with other methods. C1 UNIV VIRGINIA,DEPT COMP SCI,CHARLOTTESVILLE,VA 22903. RP AVERICK, BM (reprint author), UNIV MINNESOTA,USA,HIGH PERFORMANCE COMP RES CTR,1100 WASHINGTON AVE S,MINNEAPOLIS,MN 55414, USA. NR 8 TC 1 Z9 1 U1 0 U2 0 PU SIAM PUBLICATIONS PI PHILADELPHIA PA 3600 UNIV CITY SCIENCE CENTER, PHILADELPHIA, PA 19104-2688 SN 1064-8275 J9 SIAM J SCI COMPUT JI SIAM J. Sci. Comput. PD JAN PY 1993 VL 14 IS 1 BP 44 EP 48 DI 10.1137/0914003 PG 5 WC Mathematics, Applied SC Mathematics GA KP465 UT WOS:A1993KP46500003 ER PT J AU HANDLEY, JW JAENISCH, HM BJORK, CA RICHARDSON, LT CARRUTH, RT AF HANDLEY, JW JAENISCH, HM BJORK, CA RICHARDSON, LT CARRUTH, RT TI CHAOS AND FRACTAL ALGORITHMS APPLIED TO SIGNAL-PROCESSING AND ANALYSIS SO SIMULATION LA English DT Article DE CHAOS; FRACTALS; R/S; AIPS SYNERGETICS; SIGNAL PROCESSING AB Modern signal processing methods strive to maximize signal to noise ratios, even in the presence of severe noise. Frequently, real world data is degraded by under sampling of intrinsic periodicities, or by sampling with unevenly spaced intervals. This results in dropout or missing data, and such data sets are particularly difficult to process using conventional methods. In many cases, one must still extract as much information as possible from a given data set, although the available discrete data is sparse or very noisy. In such cases, we have found the algorithms derived from Chaos and fractal theory to represent a viable alternative to traditional spectral analysis. The data analysis techniques discussed in this work includes phase space reconstruction, Poincare sections, radius of gyration exponent, artificial insymmetration patterns (AIP), Liapunov spectra, correlation techniques, R/S analysis, K-factor, fractal statistics, maximum entropy method, and wavelets. C1 NICHOLS RES CORP,HUNTSVILLE,AL 35802. USA,STRATEG DEF COMMAND,HUNTSVILLE,AL 35807. RP HANDLEY, JW (reprint author), UNIV ALABAMA,DEPT MECH ENGN,HUNTSVILLE,AL 35899, USA. NR 53 TC 1 Z9 1 U1 0 U2 0 PU SIMULATION COUNCILS INC PI SAN DIEGO PA PO BOX 17900, SAN DIEGO, CA 92117 SN 0037-5497 J9 SIMULATION JI Simulation PD JAN PY 1993 VL 60 IS 1 BP 36 EP 53 DI 10.1177/003754979306000104 PG 18 WC Computer Science, Interdisciplinary Applications; Computer Science, Software Engineering SC Computer Science GA KK909 UT WOS:A1993KK90900003 ER PT B AU HAMMONS, MI ATKINSON, RH TIKALSKY, PJ AF HAMMONS, MI ATKINSON, RH TIKALSKY, PJ BE Hamid, AA Harris, HG TI BIAXIAL BEHAVIOR OF REINFORCED MASONRY SO SIXTH NORTH AMERICAN MASONRY CONFERENCE, PROCEEDINGS, VOLS 1 AND 2 LA English DT Proceedings Paper CT 6th North American Masonry Conference CY JUN 06-09, 1993 CL DREXEL UNIV, PHILADELPHIA, PA SP MASONRY SOC, DREXEL UNIV, NATL SCI FDN, BRICK INST AMER, DELAWARE VALLEY MASONRY INST, INT MASONRY INST, MASONRY INST AMER, NATL CONCRETE MASONRY ASSOC, PORTLAND CEMENT ASSOC, PENNSYLVANIA CONCRETE MASONRY ASSOC, W STATES CLAY PROD ASSOC HO DREXEL UNIV C1 USAE,WATERWAYS EXPT STN,STRUCT LAB,VICKSBURG,MS. NR 0 TC 0 Z9 0 U1 0 U2 1 PU MASONRY SOC PI BOULDER PA 2619 SPRUCE ST, BOULDER, CO 80302 BN 0-8407-5159-1 PY 1993 BP 1235 EP 1246 PG 12 WC Engineering, Civil SC Engineering GA BA66T UT WOS:A1993BA66T00104 ER PT J AU MCKEEHAN, I CAMPBELL, R TUMANOV, SV AF MCKEEHAN, I CAMPBELL, R TUMANOV, SV TI MOSCOWS HEALTH HABITS AND LIFE-STYLES PRIOR TO THE START OF THE 1991-1993 HEALTH-INSURANCE ACT OF RUSSIA SO SOTSIOLOGICHESKIE ISSLEDOVANIYA LA Russian DT Article C1 US MIL ACAD,W POINT,NY 10996. MOSCOW MV LOMONOSOV STATE UNIV,ONINIO RES LAB,MOSCOW,RUSSIA. RP MCKEEHAN, I (reprint author), COLUMBIA UNIV,NEW YORK,NY 10027, USA. NR 13 TC 0 Z9 0 U1 0 U2 1 PU MEZHDUNARODNAYA KNIGA PI MOSCOW PA 39 DIMITROVA UL., 113095 MOSCOW, RUSSIA SN 0132-1625 J9 SOTSIOL ISSLED+ JI Sotsiologicheskie Issled. PY 1993 IS 3 BP 45 EP 49 PG 5 WC Sociology SC Sociology GA LK614 UT WOS:A1993LK61400007 ER PT J AU TAYLOR, JP DIMMITT, DC EZZELL, JW WHITFORD, H AF TAYLOR, JP DIMMITT, DC EZZELL, JW WHITFORD, H TI INDIGENOUS HUMAN CUTANEOUS ANTHRAX IN TEXAS SO SOUTHERN MEDICAL JOURNAL LA English DT Article AB In December 1988 an indigenous case of cutaneous anthrax was identified in Texas. The patient, a 63-year-old male Hispanic from southwest Texas, was a sheep shearer and had a recent history of dissecting sheep that had died suddenly. He experienced an illness characterized by left arm pain and edema. A necrotic lesion developed on his left forearm, with cellulitis and lymphadenopathy. After treatment with oral and intravenous penicillins, the patient fully recovered. Western blot testing revealed a fourfold or greater rise in antibody titer to Bacillus anthracis protective antigen and lethal factor. This represents the first case of indigenous anthrax in Texas in more than 20 years. C1 USA,MED RES INST INFECT DIS,DIV BACTERIOL,FREDERICK,MD 21701. TEXAS VET MED DIAGNOST LABS,COLL STN,TX. RP TAYLOR, JP (reprint author), TEXAS DEPT HLTH,DIV EPIDEMIOL,1100 W 49TH ST,AUSTIN,TX 78756, USA. RI Lambrecht, Bart/M-4734-2015 NR 15 TC 10 Z9 10 U1 0 U2 0 PU SOUTHERN MEDICAL ASSN PI BIRMINGHAM PA 35 LAKESHORE DR PO BOX 190088, BIRMINGHAM, AL 35219 SN 0038-4348 J9 SOUTHERN MED J JI South.Med.J. PD JAN PY 1993 VL 86 IS 1 BP 1 EP 4 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA KJ400 UT WOS:A1993KJ40000001 PM 8420007 ER PT S AU ALVING, CR DETRICK, B RICHARDS, RL LEWIS, MG SHAFFERMAN, A EDDY, GA AF ALVING, CR DETRICK, B RICHARDS, RL LEWIS, MG SHAFFERMAN, A EDDY, GA BE Bystryn, JC Ferrone, S Livingston, P TI NOVEL ADJUVANT STRATEGIES FOR EXPERIMENTAL MALARIA AND AIDS VACCINES SO SPECIFIC IMMUNOTHERAPY OF CANCER WITH VACCINES SE ANNALS OF THE NEW YORK ACADEMY OF SCIENCES LA English DT Proceedings Paper CT CONF ON SPECIFIC IMMUNOTHERAPY OF CANCER WITH VACCINES CY JAN 21-24, 1993 CL WASHINGTON, DC SP NEW YORK ACAD SCI, NCI, BIOMIRA INC, CAMBRIDGE BIOTECH, AMER CYANAMID, BRISTOL MYERS SQUIBB, PHARM RES INST, CYTOGEN CORP, GENENTECH, GENETICS INST, HOFFMANN LA ROCHE RP ALVING, CR (reprint author), WALTER REED ARMY MED CTR,DEPT MEMBRANE BIOCHEM,WASHINGTON,DC 20307, USA. NR 0 TC 16 Z9 16 U1 0 U2 0 PU NEW YORK ACAD SCIENCES PI NEW YORK PA NEW YORK SN 0077-8923 BN 0-89766-825-1 J9 ANN NY ACAD SCI JI Ann.NY Acad.Sci. PY 1993 VL 690 BP 265 EP 275 PG 11 WC Oncology; Immunology; Pharmacology & Pharmacy SC Oncology; Immunology; Pharmacology & Pharmacy GA BY95C UT WOS:A1993BY95C00028 ER PT B AU HAYDEN, TJ TAZIK, DJ AF HAYDEN, TJ TAZIK, DJ BE Finch, DM Stangel, PW TI INTEGRATED NATURAL-RESOURCE MONITORING ON ARMY LANDS AND ITS APPLICATION TO CONSERVATION OF NEOTROPICAL BIRDS SO STATUS AND MANAGEMENT OF NEOTROPICAL MIGRATORY BIRDS SE USDA FOREST SERVICE GENERAL TECHNICAL REPORT ROCKY MOUNTAIN LA English DT Proceedings Paper CT National Training Workshop on Status and Management of Neotropical Migratory Birds CY SEP 21-25, 1992 CL YMCA ROCKIES, ESTES PK CTR, ESTES PK, CO SP US FISH & WILD SERV, US FOREST SERV, US BUR LAND MANAGEMENT, US NATL PK SERV, US DEPT DEF, WILDLIFE MANAGEMENT INST, ENVIRONM PROTECT AGCY, NATL FISH & WILDLIFE FDN HO YMCA ROCKIES, ESTES PK CTR C1 USA,CONSTRUCT ENGN RES LABS,NAT RESOURCES MANAGEMENT TEAM,CHAMPAIGN,IL 61826. NR 0 TC 1 Z9 1 U1 0 U2 0 PU US DEPT AGR, FOREST SERV ROCKY MT FOREST & RANGE EXPTL STN PI FT COLLINS PA FT COLLINS, CO 80526 J9 USDA ROCKY PY 1993 VL 229 BP 258 EP 264 PG 7 WC Ecology; Forestry; Ornithology SC Environmental Sciences & Ecology; Forestry; Zoology GA BZ66Z UT WOS:A1993BZ66Z00030 ER PT J AU BAHDER, TB TOBER, RL BRUNO, JD AF BAHDER, TB TOBER, RL BRUNO, JD TI PYROELECTRIC EFFECT IN SEMICONDUCTOR HETEROSTRUCTURES SO SUPERLATTICES AND MICROSTRUCTURES LA English DT Article AB In heterostructures made of dielectric or semiconductor materials a reduction in symmetry can lead to a pyroelectric effect in the heterostructure, even though the effect is forbidden by symmetry in the bulk-crystal constituent materials. The pyroelectric effect resulting from an applied electric field and a built-in strain is estimated for the cases of a [100] and [111] growth-axis GaAs-AlGaAs and GaAs-InGaAs quantum well. The effect is shown to produce pyroelectric coefficients on the order of p(i) = 10(-6) C/m2 K, which is comparable to some bulk-crystal pyroelectric materials. RP BAHDER, TB (reprint author), USA,RES LAB,2800 POWDER MILL RD,ADELPHI,MD 20783, USA. NR 8 TC 9 Z9 9 U1 0 U2 2 PU ACADEMIC PRESS LTD PI LONDON PA 24-28 OVAL RD, LONDON, ENGLAND NW1 7DX SN 0749-6036 J9 SUPERLATTICE MICROST JI Superlattices Microstruct. PY 1993 VL 14 IS 2-3 BP 149 EP 152 DI 10.1006/spmi.1993.1116 PG 4 WC Physics, Condensed Matter SC Physics GA PG224 UT WOS:A1993PG22400004 ER PT J AU CHIU, CJ STROSCIO, MA AF CHIU, CJ STROSCIO, MA TI NORMALIZATION OF INTERFACE OPTICAL PHONON MODES IN CYLINDRICAL QUANTUM WIRES WITH SEMICONDUCTOR-SEMICONDUCTOR AND METAL-SEMICONDUCTOR BOUNDARY-CONDITIONS SO SUPERLATTICES AND MICROSTRUCTURES LA English DT Article ID ELECTRON; HETEROSTRUCTURES; SCATTERING; SYSTEMS; GROWTH C1 USA,RES OFF,RES TRIANGLE PK,NC 27709. RP CHIU, CJ (reprint author), DUKE UNIV,DEPT ELECT ENGN,DURHAM,NC 27708, USA. NR 17 TC 1 Z9 1 U1 0 U2 1 PU ACADEMIC PRESS LTD PI LONDON PA 24-28 OVAL RD, LONDON, ENGLAND NW1 7DX SN 0749-6036 J9 SUPERLATTICE MICROST JI Superlattices Microstruct. PY 1993 VL 13 IS 4 BP 401 EP 404 DI 10.1006/spmi.1993.1079 PG 4 WC Physics, Condensed Matter SC Physics GA MF338 UT WOS:A1993MF33800002 ER PT J AU DELACRUZ, RM TEITSWORTH, SW STROSCIO, MA AF DELACRUZ, RM TEITSWORTH, SW STROSCIO, MA TI BOTTLENECK EFFECTS DUE TO CONFINED PHONONS IN QUANTUM DOTS SO SUPERLATTICES AND MICROSTRUCTURES LA English DT Article ID ELECTRON-GAS; SCATTERING; WIRE; MODES; SEMICONDUCTORS; SUPERLATTICES; RELAXATION; SYSTEMS C1 USA,RES OFF,RES TRIANGLE PK,NC 27709. UCM,FAC CC FIS,DEPT FIS MAT,E-28040 MADRID,SPAIN. RP DELACRUZ, RM (reprint author), DUKE UNIV,DEPT PHYS,BOX 90305,DURHAM,NC 27708, USA. NR 23 TC 13 Z9 13 U1 0 U2 1 PU ACADEMIC PRESS LTD PI LONDON PA 24-28 OVAL RD, LONDON, ENGLAND NW1 7DX SN 0749-6036 J9 SUPERLATTICE MICROST JI Superlattices Microstruct. PY 1993 VL 13 IS 4 BP 481 EP 486 DI 10.1006/spmi.1993.1090 PG 6 WC Physics, Condensed Matter SC Physics GA MF338 UT WOS:A1993MF33800013 ER PT B AU PETREANU, JP KUMAR, A AF PETREANU, JP KUMAR, A BE Berndt, CC Bernecki, TF TI DELEADING PAINT BY VITRIFICATION USING THERMAL SPRAY TECHNOLOGY SO THERMAL SPRAY COATINGS: RESEARCH, DESIGN AND APPLICATIONS LA English DT Proceedings Paper CT 5th National Thermal Spray Conference and Exposition on Thermal Spray Technology: Growing to Serve Industry in Surface Protection and Materials Processing (NTSC 93) CY JUN 07-11, 1993 CL ANAHEIM, CA SP ASM INT, AMER WELDING SOC, DEUT VERBAND SCHWEISSTECH E V, JAPAN THERMAL SPRAYING SOC, HIGH TEMP SOC JAPAN, INT THERMAL SPRAY ASSOC C1 USA,CONSTRUCT ENGN LAB,CHAMPAIGN,IL. NR 0 TC 1 Z9 1 U1 0 U2 0 PU ASM INTERNATIONAL PI MATERIALS PARK PA 9503 KINSMAN RD, MATERIALS PARK, OH 44073 BN 0-87170-470-6 PY 1993 BP 629 EP 634 PG 6 WC Materials Science, Multidisciplinary; Materials Science, Coatings & Films SC Materials Science GA BZ93M UT WOS:A1993BZ93M00098 ER PT S AU HSIEH, AJ HUANG, P VENKATARAMAN, SK KOHLSTEDT, DL AF HSIEH, AJ HUANG, P VENKATARAMAN, SK KOHLSTEDT, DL BE Townsend, PH Weihs, TP Sanchez, JE Borgesen, P TI MECHANICAL CHARACTERIZATION OF DIAMOND-LIKE CARBON (DLC) COATED POLYCARBONATES SO THIN FILMS: STRESSES AND MECHANICAL PROPERTIES IV SE MATERIALS RESEARCH SOCIETY SYMPOSIUM PROCEEDINGS LA English DT Proceedings Paper CT Symposium on Thin Films: Stresses and Mechanical Properties IV, at the 1993 Spring Meeting of the Materials-Research-Society CY APR 12-16, 1993 CL SAN FRANCISCO, CA SP MAT RES SOC, DOW CHEM CO, ADV MICRO DEVICES, LAWRENCE LIVERMORE NATL LAB, NANO INSTRUMENTS INC, QUAD GRP, TENCOR INSTRUMENTS, INDUSTRY CORNELL UNIV, ALLIANCE ELECTR PACKAGE C1 USA,RES LAB,WATERTOWN,MA 02172. NR 0 TC 5 Z9 5 U1 0 U2 0 PU MATERIALS RESEARCH SOC PI PITTSBURGH PA 9800 MCKNIGHT RD, SUITE 327, PITTSBURGH, PA 15237 SN 0272-9172 BN 1-55899-204-9 J9 MATER RES SOC SYMP P PY 1993 VL 308 BP 653 EP 658 DI 10.1557/PROC-308-653 PG 6 WC Materials Science, Multidisciplinary; Mechanics; Physics, Applied SC Materials Science; Mechanics; Physics GA BZ55E UT WOS:A1993BZ55E00097 ER PT J AU TOMALIA, DA DURST, HD AF TOMALIA, DA DURST, HD TI GENEALOGICALLY DIRECTED SYNTHESIS - STARBURST CASCADE DENDRIMERS AND HYPERBRANCHED STRUCTURES SO TOPICS IN CURRENT CHEMISTRY LA English DT Review ID CONVERGENT-GROWTH APPROACH; PALYTOXIN CARBOXYLIC-ACID; DENDRITIC MACROMOLECULES; MOLECULAR RECOGNITION; SUPRAMOLECULAR CHEMISTRY; PERSPECTIVES MOLECULES; <9>-N-<9> ARBOROLS; ORGANIC-CHEMISTRY; NOBEL LECTURE; COMPLEXES AB A paradigm shift is in progress which is directed at the mimicry of complex, highly sophisticated biomolecular architecture and phenomena. Mimicry of these targeted phenomena and structures is driven by the realization that these prototypes have been derived and perfected over billions of years in a dazzling molecular level effort to introduce and sustain life. In the past, natural product synthesis or de novo protein/polynucleic acid syntheses have been targeted to produce direct equivalency to various prototypes in biomolecular schemes. Unlike this objective, synthetic structures and strategies in this account will focus on the mimicry of architecture and phenomena found in life processes, utilizing less complex reagents and protocol to give novel products not found in Nature. With this in mind we introduce a new organic synthesis strategy which we refer to as ''genealogically directed synthesis'' (GDS). Simply stated the central theme of this strategy utilizes mimicry of seven key phenomena/architectural criteria invoked by Nature to initiate and sustain life. These criteria deal with the flow and transfer of molecular level information through a chemical hierarchy, be it abiotic or biological. A comparison of such GDS mimicry with certain targeted biomolecular phenomena/-structures is listed below: [GRAPHICS] These seven italicized criteria are integrated into a variety of (GDS) schemes thus allowing construction of hyperbranched macromolecular structures referred to as ''dendrons'' or ''dendrimers''. A direct consequence of this strategy is a systematic ''molecular morphogenesis'' [1] with an opportunity to control ''critical molecular design parameters'' (CMDP's); (i.e., size, shape, surface chemistry, topology and flexibility) as one advances with covalent connectivity from molecular reference points (seeds) of picoscopic/sub-nanoscopic size (i.e.. 0.01-1.0 nm) to precise macromolecular structures of nanoscopic dimensions (i.e., 1.0-100 nm) [2]. Genealogically directed synthesis offers a broad and versatile approach to the construction of precise, abiotic nanostructures with predictable sizes, shapes and surface chemistries. C1 USA, CTR CHEM RES DEV & ENGN, RES DIRECTORATE, DIV TOXICOL, ABERDEEN PROVING GROUND, MD 21010 USA. RP TOMALIA, DA (reprint author), MICHIGAN MOLEC INST, DEPT CHEM, 1910 W ST ANDREWS RD, MIDLAND, MI 48640 USA. NR 322 TC 585 Z9 600 U1 2 U2 20 PU SPRINGER VERLAG PI NEW YORK PA 175 FIFTH AVE, NEW YORK, NY 10010 SN 0342-6793 J9 TOP CURR CHEM JI Top. Curr. Chem. PY 1993 VL 165 BP 193 EP 313 PG 121 WC Chemistry, Multidisciplinary SC Chemistry GA KX838 UT WOS:A1993KX83800006 ER PT J AU PORTER, WL AF PORTER, WL TI PARADOXICAL BEHAVIOR OF ANTIOXIDANTS IN FOOD AND BIOLOGICAL-SYSTEMS SO TOXICOLOGY AND INDUSTRIAL HEALTH LA English DT Article ID ALPHA-TOCOPHEROL; ASCORBIC-ACID; PHENOLIC ANTIOXIDANTS; GAMMA-TOCOPHEROL; OILS RP PORTER, WL (reprint author), USA,NATICK RES DEV & ENGN CTR,FOOD ENGN DIRECTORATE,NATICK,MA 01760, USA. NR 60 TC 140 Z9 142 U1 1 U2 21 PU PRINCETON SCIENTIFIC PUBL INC PI PRINCETON PA PO BOX 2155, PRINCETON, NJ 08543 SN 0748-2337 J9 TOXICOL IND HEALTH JI Toxicol. Ind. Health PD JAN-APR PY 1993 VL 9 IS 1-2 BP 93 EP 122 PG 30 WC Public, Environmental & Occupational Health; Toxicology SC Public, Environmental & Occupational Health; Toxicology GA KD769 UT WOS:A1993KD76900008 PM 8418528 ER PT J AU SIMPSON, LL LAUTENSLAGER, GT KAISER, II MIDDLEBROOK, JL AF SIMPSON, LL LAUTENSLAGER, GT KAISER, II MIDDLEBROOK, JL TI IDENTIFICATION OF THE SITE AT WHICH PHOSPHOLIPASE-A2 NEUROTOXINS LOCALIZE TO PRODUCE THEIR NEUROMUSCULAR BLOCKING EFFECTS SO TOXICON LA English DT Article ID I-125-LABELED BOTULINUM NEUROTOXINS; NERVE-TERMINALS; MOTOR NERVES; CROTOXIN; TOXINS; JUNCTION; VENOM AB Experiments were conducted on mouse hemidiaphragm preparations using five phospholipase A2 neurotoxins of differing chain structures and antigenicities [notexin (one chain); crotoxin (two chains not covalently bound), beta-bungarotoxin (two chains covalently bound); taipoxin (three chains), and textilotoxin (five chains; one copy each of three chains and two copies of a fourth chain)]. Three clostridial neurotoxins (botulinum neurotoxin types A and B, and tetanus toxin) were used in comparison experiments. Phospholipase A2 neurotoxins produced concentration-dependent blockade of neuromuscular transmission. There was no obvious relationship between chain structure and potency, but there was an indication of a relationship between chain structure and binding. The binding of notexin was substantially reversible, the binding of crotoxin was slightly reversible, and the binding of beta-bungarotoxin, taipoxin and textilotoxin was poorly reversible. Experiments with neutralizing antibodies indicated that phospholipase A2 neurotoxins became associated with binding sites on or near the cell surface. This binding did not produce neuromuscular blockade. When exposed to physiological temperatures and nerve stimulation, bound toxin disappeared from accessibility to neutralizing antibody. This finding suggests that there was some form of molecular rearrangement. The two most likely possibilities are: (1) there was a change in the conformation of the toxin molecule, or (2) there was a change in the relationship between the toxin and the membrane. The molecular rearrangement step did not produce neuromuscular blockade. At a later time there was onset of paralysis; the amount of time necessary for onset of blockade was a function of toxin concentration. Phospholipase A2 neurotoxins were not antagonized by drugs that inhibit receptor-mediated endocytosis. In addition, phospholipase A2 neurotoxins did not display the pH-induced conformational changes that are typical of other endocytosed proteins, such as clostridial neurotoxins. However, phospholipase A2 neurotoxins were antagonized by strontium, and this antagonism was expressed against toxins that were free in solution and toxins that were bound to the cell surface. Limited antagonism was expressed after toxins had undergone molecular rearrangement, and no antagonism was expressed after toxin-induced neuromuscular blockade. The cumulative data suggest that phospholipase A2 neurotoxins are not internalized to produce their poisoning effects. These toxins appear to act on the plasma membrane, and this is the site at which they initiate the events that culminate in neuromuscular blockade. C1 USA,MED RES INST INFECT DIS,DEPT TOXINOL,DIV PATHOPHYSIOL,FREDERICK,MD 21702. THOMAS JEFFERSON UNIV,JEFFERSON MED COLL,DEPT PHARMACOL,PHILADELPHIA,PA 19107. UNIV WYOMING,DEPT MOLEC BIOL,LARAMIE,WY 82071. RP SIMPSON, LL (reprint author), THOMAS JEFFERSON UNIV,JEFFERSON MED COLL,DEPT MED,PHILADELPHIA,PA 19107, USA. FU NINDS NIH HHS [NS-22153] NR 23 TC 41 Z9 42 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0041-0101 J9 TOXICON JI Toxicon PD JAN PY 1993 VL 31 IS 1 BP 13 EP 26 DI 10.1016/0041-0101(93)90352-J PG 14 WC Pharmacology & Pharmacy; Toxicology SC Pharmacology & Pharmacy; Toxicology GA KG760 UT WOS:A1993KG76000001 PM 8446959 ER PT J AU ODUOLA, AMJ OMITOWOJU, GO GERENA, L KYLE, DE MILHOUS, WK SOWUNMI, A SALAKO, LA AF ODUOLA, AMJ OMITOWOJU, GO GERENA, L KYLE, DE MILHOUS, WK SOWUNMI, A SALAKO, LA TI REVERSAL OF MEFLOQUINE RESISTANCE WITH PENFLURIDOL IN ISOLATES OF PLASMODIUM-FALCIPARUM FROM SOUTH-WEST NIGERIA SO TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID CHLOROQUINE RESISTANCE; RODENT MALARIA; INVITRO; GENE; AMPLIFICATION; CHEMOTHERAPY; AFRICA AB The susceptibilities of isolates of Plasmodium falciparum from Nigeria and two reference cloned strains (D6 and W2) to mefloquine or chloroquine alone and in combination with either penfluridol, a piperidine analogue, or verapamil were determined using a modification of the semiautomated microdilution technique. Six of the isolates showed reduced susceptibility to mefloquine in vitro. The response of the 6 isolates was similar to that of the mefloquine resistant reference clone D6, with 50% inhibitory concentration (IC50) values=3.29-9.72 ng/ml. Only 2 of the Nigerian isolates were sensitive to mefloquine (IC50=1.16 ng/ml and 2.62 ng/ml) and were similar to the reference mefloquine sensitive clone W2 (IC50=1.78 ng/ml). All the isolates tested were sensitive to chloroquine, with IC50 values=1.5-3.04 ng/ml. Simultaneous incubation of the parasites with a constant sub-inhibitory concentration of penfluridol (5.0 x 10(-7) M) and mefloquine increased the susceptibility of the resistant parasites to mefloquine. Addition of the neuroleptic drug penfluridol did not alter the response of sensitive parasites to mefloquine or chloroquine. Similarly, addition of 1.0 x 10(-6) M verapamil did not affect the activity of mefloquine against the sensitive or resistant parasites. C1 UNIV IBADAN,COLL MED,DEPT PHARMACOL & THERAPEUT,IBADAN,NIGERIA. WALTER REED ARMY INST RES,DEPT EXPTL THERAPEUT,WASHINGTON,DC 20307. NR 23 TC 47 Z9 48 U1 0 U2 0 PU ROYAL SOC TROPICAL MEDICINE PI LONDON PA MANSON HOUSE 26 PORTLAND PLACE, LONDON, ENGLAND W1N 4EY SN 0035-9203 J9 T ROY SOC TROP MED H JI Trans. Roy. Soc. Trop. Med. Hyg. PD JAN-FEB PY 1993 VL 87 IS 1 BP 81 EP 83 DI 10.1016/0035-9203(93)90434-R PG 3 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA KR509 UT WOS:A1993KR50900030 PM 8465407 ER PT B AU CAMFIELD, FE AF CAMFIELD, FE BE Tinti, S TI DYNAMIC-RESPONSE OF STRUCTURES TO TSUNAMI ATTACK SO TSUNAMIS IN THE WORLD: FIFTEENTH INTERNATIONAL TSUNAMI SYMPOSIUM, 1991 SE ADVANCES IN NATURAL AND TECHNOLOGICAL HAZARDS RESEARCH LA English DT Proceedings Paper CT 15TH International Tsunami Symposium held during the XX General Assembly of the International-Union-of-Geodesy-and-Geophysics CY AUG 19-20, 1991 CL VIENNA, AUSTRIA SP INT UNION GEODESY & GEOPHYS, TSUNAMI COMMISS, INT ASSOC SEISMOL & PHYS EARTHS INTERIORS, INT ASSOC PHYS SCI OCEAN DE TSUNAMI; TSUNAMI FORCES; STRUCTURE RESPONSE; FOUNDATION FAILURE C1 USA,ENGINEER WATERWAYS EXPT STN,COASTAL ENGN RES CTR,VICKSBURG,MS 39180. NR 0 TC 0 Z9 0 U1 0 U2 0 PU KLUWER ACADEMIC PUBL PI DORDRECHT PA PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS BN 0-7923-2316-5 J9 ADV NAT TECHNOL HAZ PY 1993 VL 1 BP 133 EP 138 PG 6 WC Geosciences, Multidisciplinary; Oceanography SC Geology; Oceanography GA BZ98W UT WOS:A1993BZ98W00010 ER PT B AU MCCORKLE, JW AF MCCORKLE, JW BE Delgrande, NK Cindrich, I Johnson, PB TI EARLY RESULTS FROM THE ARMY RESEARCH LABORATORY ULTRA-WIDE-BANDWIDTHFOLIAGE PENETRATION SAR SO UNDERGROUND AND OBSCURED OBJECT IMAGING AND DETECTION SE PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE) LA English DT Proceedings Paper CT CONF ON UNDERGROUND AND OBSCURED OBJECT IMAGING AND DETECTION CY APR 15-16, 1993 CL ORLANDO, FL SP SOC PHOTO OPT INSTRUMENTAT ENGINEERS RP MCCORKLE, JW (reprint author), USA,RES LAB,ADELPHI,MD 20783, USA. NR 0 TC 2 Z9 2 U1 0 U2 0 PU SPIE - INT SOC OPTICAL ENGINEERING PI BELLINGHAM PA BELLINGHAM BN 0-8194-1178-7 J9 P SOC PHOTO-OPT INS PY 1993 VL 1942 BP 88 EP 95 DI 10.1117/12.160352 PG 8 WC Optics SC Optics GA BZ37C UT WOS:A1993BZ37C00009 ER PT J AU REID, RH BOEDEKER, EC MCQUEEN, CE DAVIS, D TSENG, LY KODAK, J SAU, K WILHELMSEN, CL NELLORE, R DALAL, P BHAGAT, HR AF REID, RH BOEDEKER, EC MCQUEEN, CE DAVIS, D TSENG, LY KODAK, J SAU, K WILHELMSEN, CL NELLORE, R DALAL, P BHAGAT, HR TI PRECLINICAL EVALUATION OF MICROENCAPSULATED CFA/II ORAL VACCINE AGAINST ENTEROTOXIGENIC ESCHERICHIA-COLI SO VACCINE LA English DT Article; Proceedings Paper CT INTERNATIONAL CONF ON VACCINES FOR ENTERIC DISEASES CY APR 13-15, 1992 CL ROBINSON COLL, CAMBRIDGE, ENGLAND SP WHO, VACCINE HO ROBINSON COLL DE ORAL VACCINE; CFA/II BIODEGRADABLE POLYMER MICROSPHERES; PEYER PATCH; SPLEEN; ANTIBODY TITERS; IMMUNOGENIC; LYMPHOCYTE PROLIFERATION ID TOXIGENIC ESCHERICHIA-COLI; BIODEGRADABLE MICROSPHERES; IMMUNE-RESPONSES; DELIVERY SYSTEM; CELLS AB Colonization Factor Antigen (CFA /II) from enterotoxigenic Escherichia coli (ETEC) prepared under good manufacturing practices (GMP) was successfully incorporated into biodegradable poly(D,L-lactide-co-glycolide) (PLGA) polymer microspheres (BPM) under GMP and found to be safe and immunogenic when administered intraduodenally to rabbits. Following vaccination, Peyer's patch cells responded by lymphocyte proliferation to in vitro challenge with CFA/II. Also, B cells secreting specific anti-CFA/II antibodies were found in spleens following vaccination. No pathological changes were found following total necropsies of ten rabbits vaccinated with CFA/II BPM. Sixty-three per cent of the CFA/II BPM were between 5 and 10 mum diameter by volume particle size distribution; 1.17% protein content; 2.15% moisture; <0.01% acetonitrile; 1.6% heptane; 22 non-pathogenic bacteria and three fungi per 1 mg protein dose; and passed the general safety test. We conclude that the CFA/II BPM oral vaccine is immunogenic and safe to begin a Phase I clinical safety study following Investigational New Drug approval. C1 WALTER REED ARMY INST RES,DEPT COMPARAT PATHOL,WASHINGTON,DC 20307. UNIV MARYLAND,SCH PHARM,DEPT PHARMACEUT,BALTIMORE,MD 21202. RP REID, RH (reprint author), WALTER REED ARMY INST RES,DEPT GASTROENTEROL,WASHINGTON,DC 20307, USA. NR 16 TC 41 Z9 43 U1 0 U2 2 PU BUTTERWORTH-HEINEMANN LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB SN 0264-410X J9 VACCINE JI Vaccine PY 1993 VL 11 IS 2 BP 159 EP 167 DI 10.1016/0264-410X(93)90013-N PG 9 WC Immunology; Medicine, Research & Experimental SC Immunology; Research & Experimental Medicine GA KH507 UT WOS:A1993KH50700013 PM 8438614 ER PT J AU MALLETT, CP VANDEVERG, L COLLINS, HH HALE, TL AF MALLETT, CP VANDEVERG, L COLLINS, HH HALE, TL TI EVALUATION OF SHIGELLA VACCINE SAFETY AND EFFICACY IN AN INTRANASALLY CHALLENGED MOUSE MODEL SO VACCINE LA English DT Article; Proceedings Paper CT INTERNATIONAL CONF ON VACCINES FOR ENTERIC DISEASES CY APR 13-15, 1992 CL ROBINSON COLL, CAMBRIDGE, ENGLAND SP WHO, VACCINE HO ROBINSON COLL DE SHIGELLA-FLEXNERI VACCINATION; INTRANASAL CHALLENGE; MOUSE MODEL ID LIVE VACCINE; FLEXNERI 2A; CANDIDATE STRAINS; CONSTRUCTION; SHIGELLA-FLEXNERI-2A; PROTECTION; INFECTION; IMMUNITY; SONNEI AB Five Shigella vaccine candidates (EcSf2a-1, EcSf2a-2, Sfl124, T32-Istrati and SMD) were tested for safety and efficacy in Balb/cJ mice using an intranasal challenge model. Experiments in this model suggest that (i) the relative attenuation of vaccines can be determined in mice by intranasal inoculation, (ii) all vaccines tested elicited antibacterial mucosal immunity protecting against pulmonary infection with Shigella flexneri 2a, (iii) protection was associated with serum IgA and/or IgG antibody recognizing the 2a somatic antigen. C1 WALTER REED ARMY INST RES,DEPT ENTER INFECT,WASHINGTON,DC 20307. NR 29 TC 58 Z9 61 U1 0 U2 0 PU BUTTERWORTH-HEINEMANN LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB SN 0264-410X J9 VACCINE JI Vaccine PY 1993 VL 11 IS 2 BP 190 EP 196 DI 10.1016/0264-410X(93)90016-Q PG 7 WC Immunology; Medicine, Research & Experimental SC Immunology; Research & Experimental Medicine GA KH507 UT WOS:A1993KH50700016 PM 8438617 ER PT J AU MCQUEEN, CE BOEDEKER, EC REID, R JARBOE, D WOLF, M LE, M BROWN, WR AF MCQUEEN, CE BOEDEKER, EC REID, R JARBOE, D WOLF, M LE, M BROWN, WR TI PILI IN MICROSPHERES PROTECT RABBITS FROM DIARRHEA INDUCED BY ESCHERICHIA-COLI STRAIN RDEC-1 SO VACCINE LA English DT Article; Proceedings Paper CT INTERNATIONAL CONF ON VACCINES FOR ENTERIC DISEASES CY APR 13-15, 1992 CL ROBINSON COLL, CAMBRIDGE, ENGLAND SP WHO, VACCINE HO ROBINSON COLL DE ENTERIC VACCINE; MUCOSAL IMMUNITY; BILIARY IGA; MUCOSAL ATTACHMENT; ENTEROADHERENT ESCHERICHIA-COLI ID ENTEROPATHOGENIC ESCHERICHIA-COLI; VACCINE DELIVERY SYSTEM; BIODEGRADABLE MICROSPHERES; IMMUNE-RESPONSES; RAT-LIVER; MUCOSAL; CHALLENGE; AF/R1; CELLS AB We tested whether pilus proteins of rabbit diarrhoeagenic Escherichia coli (RDEC-1), incorporated into biodegradable microspheres, could function as safe and effective oral immunogens in the rabbit diarrhoea model. The RDEC-1 adhesin, AF/R1, incorporated into poly(D,L-lactide-co-glycolide) microspheres, was administered intraduodenally. Vaccinated and unvaccinated rabbits were challenged with RDEC-1 and killed 1 week later. Vaccination with AF/R1 in microspheres did not cause diarrhoea or weight loss. After challenge, rabbits given AF/R1 in microspheres, in contrast to unvaccinated animals, remained in good health. RDEC-1 attachment to caecal epithelium of vaccinated rabbits was reduced (p = 0.02), whereas numbers of RDEC-1 in intestinal fluids were little affected. Also, in vaccinated animals, biliary anti-AF/R1 IgA levels were increased, and AF/R1-induced blast-cell transformation was vigorous in spleen cell cultures. We conclude that vaccination with AF/R1 in microspheres was safe and protected rabbits against RDEC-1 disease, probably by interfering with adherence of the bacteria to the intestinal mucosa. The interference might have been due to the presence of specific antibodies secreted in bile. C1 UNIV COLORADO,SCH MED,DENVER,CO 80220. VET ADM MED CTR,DEPT MED,DENVER,CO 80220. RP MCQUEEN, CE (reprint author), WALTER REED ARMY INST RES,DEPT GASTROENTEROL,BLDG 40,WASHINGTON,DC 20307, USA. NR 28 TC 24 Z9 24 U1 0 U2 0 PU BUTTERWORTH-HEINEMANN LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB SN 0264-410X J9 VACCINE JI Vaccine PY 1993 VL 11 IS 2 BP 201 EP 206 DI 10.1016/0264-410X(93)90018-S PG 6 WC Immunology; Medicine, Research & Experimental SC Immunology; Research & Experimental Medicine GA KH507 UT WOS:A1993KH50700018 PM 8094930 ER PT B AU REUSS, M AF REUSS, M BE Reuss, M TI WATER-RESOURCES ADMINISTRATION IN THE UNITED-STATES - POLICY, PRACTICE, AND EMERGING ISSUES - INTRODUCTION SO WATER RESOURCES ADMINISTRATION IN THE UNITED STATES: POLICY, PRACTICE, AND EMERGING ISSUES LA English DT Proceedings Paper CT American-Water-Resources-Association National Forum on Water Management Policy CY JUN 28-JUL 01, 1992 CL WASHINGTON, DC SP AMER WATER RESOURCES ASSOC, NATL CAPITAL SECT, AMER PUBLIC WORKS ASSOC, US BUR RECLAMAT, US FISH & WILDLIFE SERV, INTERSTATE COUNCIL WATER POLICY, SALT RIVER PROJECT, US SOIL & WATER CONSERVAT SERV, TENNESSEE VALLEY AUTHORITY, US EPA C1 USA,CORP ENGINEERS,HEADQUARTERS,OFF HIST,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MICHIGAN STATE UNIV PRESS PI E LANSING PA 1405 S HARRISON RD SUITE 25, MANLY MILES BLDG, E LANSING, MI 48823-5202 BN 0-87013-333-0 PY 1993 BP 1 EP 8 PG 8 WC Economics; Engineering, Environmental; Political Science; Public Administration; Water Resources SC Business & Economics; Engineering; Government & Law; Public Administration; Water Resources GA BA87R UT WOS:A1993BA87R00001 ER PT B AU WILLIAMS, AE AF WILLIAMS, AE BE Reuss, M TI THE ROLE OF TECHNOLOGY IN SUSTAINABLE DEVELOPMENT SO WATER RESOURCES ADMINISTRATION IN THE UNITED STATES: POLICY, PRACTICE, AND EMERGING ISSUES LA English DT Proceedings Paper CT American-Water-Resources-Association National Forum on Water Management Policy CY JUN 28-JUL 01, 1992 CL WASHINGTON, DC SP AMER WATER RESOURCES ASSOC, NATL CAPITAL SECT, AMER PUBLIC WORKS ASSOC, US BUR RECLAMAT, US FISH & WILDLIFE SERV, INTERSTATE COUNCIL WATER POLICY, SALT RIVER PROJECT, US SOIL & WATER CONSERVAT SERV, TENNESSEE VALLEY AUTHORITY, US EPA C1 USA,CORPS ENGINEERS,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MICHIGAN STATE UNIV PRESS PI E LANSING PA 1405 S HARRISON RD SUITE 25, MANLY MILES BLDG, E LANSING, MI 48823-5202 BN 0-87013-333-0 PY 1993 BP 120 EP 129 PG 10 WC Economics; Engineering, Environmental; Political Science; Public Administration; Water Resources SC Business & Economics; Engineering; Government & Law; Public Administration; Water Resources GA BA87R UT WOS:A1993BA87R00010 ER PT B AU DIETZ, AL AF DIETZ, AL BE Reuss, M TI ALLIANCES - THE NEW FOUNDATION FOR AMERICA PORTS AND WATERWAYS SO WATER RESOURCES ADMINISTRATION IN THE UNITED STATES: POLICY, PRACTICE, AND EMERGING ISSUES LA English DT Proceedings Paper CT American-Water-Resources-Association National Forum on Water Management Policy CY JUN 28-JUL 01, 1992 CL WASHINGTON, DC SP AMER WATER RESOURCES ASSOC, NATL CAPITAL SECT, AMER PUBLIC WORKS ASSOC, US BUR RECLAMAT, US FISH & WILDLIFE SERV, INTERSTATE COUNCIL WATER POLICY, SALT RIVER PROJECT, US SOIL & WATER CONSERVAT SERV, TENNESSEE VALLEY AUTHORITY, US EPA C1 USA,CTR NAVIGAT DATA,CORPS ENGINEERS,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MICHIGAN STATE UNIV PRESS PI E LANSING PA 1405 S HARRISON RD SUITE 25, MANLY MILES BLDG, E LANSING, MI 48823-5202 BN 0-87013-333-0 PY 1993 BP 218 EP 230 PG 13 WC Economics; Engineering, Environmental; Political Science; Public Administration; Water Resources SC Business & Economics; Engineering; Government & Law; Public Administration; Water Resources GA BA87R UT WOS:A1993BA87R00017 ER PT B AU STEINBERG, B AF STEINBERG, B BE Reuss, M TI THE FEDERAL PERSPECTIVE SO WATER RESOURCES ADMINISTRATION IN THE UNITED STATES: POLICY, PRACTICE, AND EMERGING ISSUES LA English DT Proceedings Paper CT American-Water-Resources-Association National Forum on Water Management Policy CY JUN 28-JUL 01, 1992 CL WASHINGTON, DC SP AMER WATER RESOURCES ASSOC, NATL CAPITAL SECT, AMER PUBLIC WORKS ASSOC, US BUR RECLAMAT, US FISH & WILDLIFE SERV, INTERSTATE COUNCIL WATER POLICY, SALT RIVER PROJECT, US SOIL & WATER CONSERVAT SERV, TENNESSEE VALLEY AUTHORITY, US EPA C1 USA,CORPS ENGINEERS,DIV PROJECT MANAGEMENT,WASHINGTON,DC 20310. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MICHIGAN STATE UNIV PRESS PI E LANSING PA 1405 S HARRISON RD SUITE 25, MANLY MILES BLDG, E LANSING, MI 48823-5202 BN 0-87013-333-0 PY 1993 BP 264 EP 273 PG 10 WC Economics; Engineering, Environmental; Political Science; Public Administration; Water Resources SC Business & Economics; Engineering; Government & Law; Public Administration; Water Resources GA BA87R UT WOS:A1993BA87R00021 ER PT J AU COLBECK, SC AF COLBECK, SC TI THE VAPOR DIFFUSION-COEFFICIENT FOR SNOW SO WATER RESOURCES RESEARCH LA English DT Article ID DRY SNOW; METAMORPHISM AB The coefficients of diffusion for water vapor in snow and other porous media are fundamental parameters of great importance. While they are generally thought to be greater than the coefficient for air, there is much uncertainty about what value to use. Attempts to determine the diffusion coefficient in snow experimentally have led to contradictory results, but Yosida's experiments seem to give reasonable results. Yosida's idea of hand-to-hand diffusion is quantified here in a particle-to-particle model which shows that the diffusion coefficient depends on the mean pore size and that the coefficient in snow is four to seven times greater than in air. RP COLBECK, SC (reprint author), USA,COLD REG RES & ENGN LAB,72 LYME RD,HANOVER,NH 03755, USA. NR 23 TC 34 Z9 34 U1 1 U2 8 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 SN 0043-1397 J9 WATER RESOUR RES JI Water Resour. Res. PD JAN PY 1993 VL 29 IS 1 BP 109 EP 115 DI 10.1029/92WR02301 PG 7 WC Environmental Sciences; Limnology; Water Resources SC Environmental Sciences & Ecology; Marine & Freshwater Biology; Water Resources GA KG914 UT WOS:A1993KG91400008 ER PT J AU MARTEL, CJ AF MARTEL, CJ TI FUNDAMENTALS OF SLUDGE DEWATERING IN FREEZING BEDS SO WATER SCIENCE AND TECHNOLOGY LA English DT Article; Proceedings Paper CT SPECIALISED CONF ON WASTEWATER SLUDGE DEWATERING : THEORETICAL METHODS, EXPERIMENTAL AND MODELLING TECHNIQUES, FULL-SCALE OPERATION AND CONTROL CY JUN 29-JUL 01, 1992 CL AALBORG, DENMARK SP DANISH TECH RES COUNCIL, INT ASSOC WATER QUAL, EUROPEAN WATER POLLUT CONTROL ASSOC, INT SOLID WASTES ASSOC DE SLUDGE FREEZING BED; SLUDGE FREEZING; FREEZE-THAW CONDITIONING; SLUDGE DEWATERING; FREEZE SEPARATION AB After several years of research, the U.S. Army Cold Regions Research and Engineering Laboratory (CRREL) has developed a new unit operation for sludge dewatering called a freezing bed. The freezing bed uses natural freeze-thaw to dewater sludge. Essentially, it is the cold regions counterpart to the drying bed. Pilot and full-scale studies conducted in the United States have demonstrated that freezing beds can dewater both water and wastewater treatment sludges to greater than 20% total solids content. The best results were obtained with alum sludge, which was dewatered to 82% solids. The design of freezing beds will depend on the depth of sludge that can be frozen and thawed at the proposed site. Mathematical models capable of calculating the design depth are presented. RP MARTEL, CJ (reprint author), USA,COLD REG RES & ENGN LAB,HANOVER,NH 03755, USA. NR 8 TC 18 Z9 19 U1 0 U2 2 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0273-1223 J9 WATER SCI TECHNOL JI Water Sci. Technol. PY 1993 VL 28 IS 1 BP 29 EP 35 PG 7 WC Engineering, Environmental; Environmental Sciences; Water Resources SC Engineering; Environmental Sciences & Ecology; Water Resources GA LZ844 UT WOS:A1993LZ84400005 ER PT J AU SCHOLZE, R NOVOTNY, V SCHONTER, R AF SCHOLZE, R NOVOTNY, V SCHONTER, R TI EFFICIENCY OF BEST MANAGEMENT-PRACTICES FOR CONTROLLING PRIORITY POLLUTANTS IN RUNOFF SO WATER SCIENCE AND TECHNOLOGY LA English DT Article; Proceedings Paper CT 1ST INTERNATIONAL CONF ON DIFFUSE ( NONPOINT ) POLLUTION : SOURCES, PREVENTION, IMPACT, ABATEMENT CY SEP 19-24, 1993 CL CHICAGO, IL SP INT ASSOC WATER QUAL, USDA, WORKING GRP WATER QUAL, US DEPT TRANSPORT, FED HIGHWAY ADM, US EPA, REG 5, US EPA, ENVIRONM RES LAB, ATHENS MARQUETTE UNIV DE BEST MANAGEMENT PRACTICES; PRIORITY POLLUTANTS; POLLUTANT REMOVAL; TOXICITY REDUCTION; REMOVAL EFFICIENCIES; DIFFUSE POLLUTION; NONPOINT POLLUTION ID SORPTION AB All priority pollutants are removed from runoff via one or more of the following pathways: adsorption or precipitation and/or complexation followed by sedimentation or filtration, volatilization, biodegradation or photolysis. The more appropriate removal mechanism may be determined by examining certain chemical parameters, especially the octanol-water partitioning coefficient K(ow), Henry's law constant K(H), vapor pressure and biodegradability. Best Management Practices may be divided into categories based on the pollutant removal mechanisms within the BMP. The most appropriate BMP may be selected by matching the process most likely to remove the pollutant to the removal process. C1 MARQUETTE UNIV,MILWAUKEE,WI 53233. AQUANOVA INT LTD,MEQUON,WI. RP SCHOLZE, R (reprint author), USA,CORPS ENGINEERS,CONSTRUCT ENGN RES LAB,CHAMPAIGN,IL, USA. NR 36 TC 4 Z9 4 U1 0 U2 1 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0273-1223 J9 WATER SCI TECHNOL JI Water Sci. Technol. PY 1993 VL 28 IS 3-5 BP 215 EP 224 PG 10 WC Engineering, Environmental; Environmental Sciences; Water Resources SC Engineering; Environmental Sciences & Ecology; Water Resources GA MA148 UT WOS:A1993MA14800027 ER PT J AU DEMPSEY, BA TAI, YL HARRISON, SG AF DEMPSEY, BA TAI, YL HARRISON, SG TI MOBILIZATION AND REMOVAL OF CONTAMINANTS ASSOCIATED WITH URBAN DUST AND DIRT SO WATER SCIENCE AND TECHNOLOGY LA English DT Article; Proceedings Paper CT 1ST INTERNATIONAL CONF ON DIFFUSE ( NONPOINT ) POLLUTION : SOURCES, PREVENTION, IMPACT, ABATEMENT CY SEP 19-24, 1993 CL CHICAGO, IL SP INT ASSOC WATER QUAL, USDA, WORKING GRP WATER QUAL, US DEPT TRANSPORT, FED HIGHWAY ADM, US EPA, REG 5, US EPA, ENVIRONM RES LAB, ATHENS MARQUETTE UNIV DE URBAN RUNOFF; TRACE METALS; NUTRIENTS; CONTAMINANTS; WATER QUALITY; MODELING; ADSORPTION; PARTITION COEFFICIENTS; ACID PRECIPITATION ID EQUILIBRIUM AB The objective of this research was to examine the effects of pH and contaminant/sorbent concentrations on the partitioning of contaminants in urban dust and dirt. An emphasis has been placed on the environmental behavior of trace metals. Contaminants in urban dust and dirt are primarily associated with particles, even after suspension in runoff water for several hours to days. This affects the reactivity, toxicity, and mobility of the contaminants. Particle size distributions (PSD) for urban dust and dirt and partition coefficients (K(p) for the distribution of various contaminants between the water and the particles of various sizes are described. Where streams have very low alkalinity or in areas affected by acid precipitation, there can be substantial decrease in pH with dilution of the initial runoff. This has a significant effect on the speciation of contaminants, and therefore on the reactivity and mobility of contaminants in urban runoff. C1 HAVENS & EMERSON ENVIRONM ENGINEERS,SADDLE BROOK,NJ 07662. US MIL ACAD,DEPT CHEM,W POINT,NY 10996. RP DEMPSEY, BA (reprint author), PENN STATE UNIV,DEPT CIVIL & ENVIRONM ENGN,UNIV PK,PA 16802, USA. RI Dempsey, Brian/G-3482-2011 NR 14 TC 19 Z9 22 U1 0 U2 3 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0273-1223 J9 WATER SCI TECHNOL JI Water Sci. Technol. PY 1993 VL 28 IS 3-5 BP 225 EP 230 PG 6 WC Engineering, Environmental; Environmental Sciences; Water Resources SC Engineering; Environmental Sciences & Ecology; Water Resources GA MA148 UT WOS:A1993MA14800028 ER PT J AU KULLBERG, PG FREDETTE, TJ AF KULLBERG, PG FREDETTE, TJ TI MANAGEMENT OF DREDGED MATERIAL CAPPING PROJECTS - AN EXAMPLE FROM NEW-ENGLAND SO WATER SCIENCE AND TECHNOLOGY LA English DT Article; Proceedings Paper CT 1st International Specialized Conference on Contaminated Aquatic Sediments: Historical Records, Environmental Impact, and Remediation CY JUN 14-16, 1993 CL MILWAUKEE, WI DE DREDGED MATERIAL; MANAGEMENT; CAPPING; DAMOS; NEW-ENGLAND AB Capping of contaminated sediments with cleaner sediments is a technique that has been used by the US Army Corps of Engineers, New England Division (NED) since 1979, to avoid or minimize the impacts of contaminated sediments disposed at open water sites. A case study of contaminated sediments from a project on the Thames River, capped at a disposal site offshore of New London, Connecticut, illustrates the application of this technique. Several steps, both regulatory and operational, must be accomplished to ensure proper employment of this technique. First, once it is determined through the permit evaluation process that material to be dredged from a project is not suitable for unconfined open water disposal, the quantity of uncontaminated dredged material needed to achieve a desired cap thickness of 50 to 100 cm must be identified. This quantity may be determined by the use of a computer model - the DAMOS (Disposal Area Monitoring System) Capping Model - which simulates the disposal events and mound formation. Next, the applicant/project proponent must submit a capping plan to NED, which includes provisions for obtaining the necessary quantity of cap material and a schedule for dredging and disposal of both contaminated and cap materials. Upon approval of this plan by NED, the contaminated material may be dredged and disposed at a taut-wire moored buoy located at a specified set of coordinates. The use of such a buoy is critical to the success of capping, since it aids in limiting the distribution of the contaminated material on the seafloor. Post-disposal bathymetric and sediment-profile camera surveys of the contaminated material are conducted to delineate the areal extent of the mound formed during disposal. Several sets of coordinates are then chosen by NED for disposal of the cap material, with the aim of covering all contaminated sediments. The operational success of the capping technique is measured by adequate areal coverage and thickness of the cap over the contaminated material. Thus, following disposal (and sometimes during disposal) of cap material, additional surveys are conducted for this purpose. RP KULLBERG, PG (reprint author), USA,CORPS ENGINEERS,NEW ENGLAND DIV,424 TRAPELO RD,WALTHAM,MA 02254, USA. NR 9 TC 1 Z9 1 U1 1 U2 3 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0273-1223 J9 WATER SCI TECHNOL JI Water Sci. Technol. PY 1993 VL 28 IS 8-9 BP 273 EP 281 PG 9 WC Engineering, Environmental; Environmental Sciences; Water Resources SC Engineering; Environmental Sciences & Ecology; Water Resources GA ND452 UT WOS:A1993ND45200030 ER PT J AU ENGEL, BA SRINIVASAN, R ARNOLD, J REWERTS, C BROWN, SJ AF ENGEL, BA SRINIVASAN, R ARNOLD, J REWERTS, C BROWN, SJ TI NONPOINT-SOURCE (NPS) POLLUTION MODELING USING MODELS INTEGRATED WITH GEOGRAPHIC INFORMATION-SYSTEMS (GIS) SO WATER SCIENCE AND TECHNOLOGY LA English DT Article; Proceedings Paper CT 1ST INTERNATIONAL CONF ON DIFFUSE ( NONPOINT ) POLLUTION : SOURCES, PREVENTION, IMPACT, ABATEMENT CY SEP 19-24, 1993 CL CHICAGO, IL SP INT ASSOC WATER QUAL, USDA, WORKING GRP WATER QUAL, US DEPT TRANSPORT, FED HIGHWAY ADM, US EPA, REG 5, US EPA, ENVIRONM RES LAB, ATHENS MARQUETTE UNIV DE GEOGRAPHIC INFORMATION SYSTEMS (GIS); NONPOINT SOURCE (NPS) POLLUTION; MODELING AB Models play an important role in the estimation of nonpoint source (NPS) pollution severity and in the identification of NPS problem areas. The use of these models has been severely limited because of the data and expertise required to operate these models. The integration of NPS pollution models with geographic information systems (GIS) can likely overcome these problems. Three NPS pollution models that were integrated with a GIS were used to simulate a watershed response to a series of rainfall events. The simulated responses were compared with observed runoff and sediment data. The simulated results matched the observed results reasonably well considering model inputs were estimated from base GIS data. C1 BLACKLANDS RES CTR,TEMPLE,TX 76502. USA CERL,CHAMPAIGN,IL 61826. RP ENGEL, BA (reprint author), PURDUE UNIV,W LAFAYETTE,IN 47907, USA. RI Srinivasan, R/D-3937-2009 NR 16 TC 39 Z9 51 U1 0 U2 4 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0273-1223 J9 WATER SCI TECHNOL JI Water Sci. Technol. PY 1993 VL 28 IS 3-5 BP 685 EP 690 PG 6 WC Engineering, Environmental; Environmental Sciences; Water Resources SC Engineering; Environmental Sciences & Ecology; Water Resources GA MA148 UT WOS:A1993MA14800078 ER PT B AU MISSLER, JM KAMANGAR, FA AF MISSLER, JM KAMANGAR, FA GP INT NEURAL NETWORK SOC TI A NEURAL-NETWORK FOR MOVING OBJECT DETECTION AND TRACKING INSPIRED BY THE FLY VISUAL-SYSTEM SO WCNN'93 - PORTLAND, WORLD CONGRESS ON NEURAL NETWORKS, VOL I LA English DT Proceedings Paper CT World Congress on Neural Networks (WCNN 93, Portland) CY JUL 11-15, 1993 CL PORTLAND, OR SP INT NEURAL NETWORK SOC C1 USA MIL ACAD,DEPT ELECT ENGN & COMP SCI,W POINT,NY 10996. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LAWRENCE ERLBAUM ASSOC PUBL PI MAHWAH PA 10 INDUSTRIAL AVE, MAHWAH, NJ 07430 BN 0-8058-1497-3 PY 1993 BP 62 EP 67 PG 6 WC Computer Science, Artificial Intelligence; Neurosciences SC Computer Science; Neurosciences & Neurology GA BA45U UT WOS:A1993BA45U00016 ER PT B AU TRAN, TC CHEN, PF AF TRAN, TC CHEN, PF GP INT NEURAL NETWORK SOC TI WATER REGIONS EXTRACTION FROM RADAR IMAGERY USING A NEURAL-NETWORK SO WCNN'93 - PORTLAND, WORLD CONGRESS ON NEURAL NETWORKS, VOL IV LA English DT Proceedings Paper CT World Congress on Neural Networks (WCNN 93, Portland) CY JUL 11-15, 1993 CL PORTLAND, OR SP INT NEURAL NETWORK SOC C1 USA,CTR TOPOG ENGN,FT BELVOIR,VA 22060. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LAWRENCE ERLBAUM ASSOC PUBL PI MAHWAH PA 10 INDUSTRIAL AVE, MAHWAH, NJ 07430 BN 0-8058-1497-3 PY 1993 BP 51 EP 54 PG 4 WC Computer Science, Artificial Intelligence; Neurosciences; Physics, Mathematical SC Computer Science; Neurosciences & Neurology; Physics GA BA45X UT WOS:A1993BA45X00012 ER PT B AU JOHNSON, JL AF JOHNSON, JL GP INT NEURAL NETWORK SOC TI WAVES IN PULSE-COUPLED NEURAL NETWORKS SO WCNN'93 - PORTLAND, WORLD CONGRESS ON NEURAL NETWORKS, VOL IV LA English DT Proceedings Paper CT World Congress on Neural Networks (WCNN 93, Portland) CY JUL 11-15, 1993 CL PORTLAND, OR SP INT NEURAL NETWORK SOC C1 USA,MISSILE COMMAND,CTR RES ENGN & DEV,WEAPONS SCI DIRECTORATE,WEAPONS SCI DIRECTORATE,PO,WS,REDSTONE ARSENAL,AL 35898. NR 0 TC 1 Z9 1 U1 0 U2 0 PU LAWRENCE ERLBAUM ASSOC PUBL PI MAHWAH PA 10 INDUSTRIAL AVE, MAHWAH, NJ 07430 BN 0-8058-1497-3 PY 1993 BP 299 EP 302 PG 4 WC Computer Science, Artificial Intelligence; Neurosciences; Physics, Mathematical SC Computer Science; Neurosciences & Neurology; Physics GA BA45X UT WOS:A1993BA45X00064 ER PT J AU NELSON, LS GETSINGER, KD LUU, KT AF NELSON, LS GETSINGER, KD LUU, KT TI EFFECT OF CHEMICAL TREATMENTS ON BAHIAGRASS (PASPALUM-NOTATUM) SUPPRESSION SO WEED TECHNOLOGY LA English DT Article DE GROUNDS MAINTENANCE; MOWING REDUCTION; TURF; CHLORSULFURON; IMAZETHAPYR; IMAZAPYR; MALEIC HYDRAZIDE; MEFLUIDIDE; FLUAZIFOP-P; SULFOMETURON; PASPALUM-NOTATUM; PASNO AB Field studies were conducted at Charleston, SC to evaluate the effects of six chemical treatments on bahiagrass and the potential of these treatments to reduce mowing operations. Sulfometuron, maleic hydrazide, and imazethapyr plus imazapyr, in decreasing order of effectiveness, were the most consistent treatments evaluated during the 2-yr study. Sulfometuron reduced bahiagrass vegetative height (23%) for 6 to 8 WAT and suppressed 87 to 92% of seedheads without adversely affecting turf quality. All treatments temporarily discolored turf; however, effects were not objectionable for medium- to low-quality turf settings. Sulfometuron, maleic hydrazide, and imazethapyr plus imazapyr controlled growth and maintained acceptable turf quality for an average of 9, 9, and 8 wk, respectively; thereby reducing mowing operations by an average 29%. Mefluidide plus fluazifop-P, mefluidide plus sulfometuron, and chlorosulfuron were the least effective and/or consistent treatments evaluated. RP NELSON, LS (reprint author), USA,ENVIRONM LAB,ENGINEER WATERWAYS EXP STN,3909 HALLS FERRY RD,VICKSBURG,MS 39180, USA. NR 0 TC 6 Z9 8 U1 1 U2 1 PU WEED SCI SOC AMER PI CHAMPAIGN PA 309 W CLARK ST, CHAMPAIGN, IL 61820 SN 0890-037X J9 WEED TECHNOL JI Weed Technol. PD JAN-MAR PY 1993 VL 7 IS 1 BP 127 EP 133 PG 7 WC Agronomy; Plant Sciences SC Agriculture; Plant Sciences GA KW883 UT WOS:A1993KW88300022 ER PT J AU DALRYMPLE, JM AF DALRYMPLE, JM TI DOD-SPONSORED VIRUS-VACCINE DEVELOPMENT - AN INVESTIGATORS PERSPECTIVE SO ANNALS OF THE NEW YORK ACADEMY OF SCIENCES LA English DT Article ID EQUINE ENCEPHALITIS-VIRUS; YELLOW-FEVER RP DALRYMPLE, JM (reprint author), USA,MED RES INST INFECT DIS,DIV VIROL,FT DETRICK,FREDERICK,MD 21702, USA. NR 16 TC 4 Z9 4 U1 0 U2 0 PU NEW YORK ACAD SCIENCES PI NEW YORK PA 2 E 63RD ST, NEW YORK, NY 10021 SN 0077-8923 J9 ANN NY ACAD SCI JI Ann. N.Y. Acad. Sci. PD DEC 31 PY 1992 VL 666 BP 202 EP 218 DI 10.1111/j.1749-6632.1992.tb38031.x PG 17 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA KX223 UT WOS:A1992KX22300014 PM 1297278 ER PT J AU MILLARD, CB BROOMFIELD, CA AF MILLARD, CB BROOMFIELD, CA TI A COMPUTER-MODEL OF GLYCOSYLATED HUMAN BUTYRYLCHOLINESTERASE SO BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS LA English DT Article ID HUMAN-SERUM CHOLINESTERASE; LINKED OLIGOSACCHARIDES; DISULFIDE BONDS; ACETYLCHOLINESTERASE; SEQUENCE; GRAPHICS; PROTEINS RP MILLARD, CB (reprint author), USA,MED RES INST CHEM DEF,ABERDEEN PROVING GROUND,MD 21010, USA. NR 25 TC 31 Z9 32 U1 0 U2 2 PU ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 SN 0006-291X J9 BIOCHEM BIOPH RES CO JI Biochem. Biophys. Res. Commun. PD DEC 30 PY 1992 VL 189 IS 3 BP 1280 EP 1286 DI 10.1016/0006-291X(92)90212-4 PG 7 WC Biochemistry & Molecular Biology; Biophysics SC Biochemistry & Molecular Biology; Biophysics GA KF545 UT WOS:A1992KF54500005 PM 1482344 ER PT J AU KERWOOD, DE SCHNEIDER, H YAMASAKI, R AF KERWOOD, DE SCHNEIDER, H YAMASAKI, R TI STRUCTURAL-ANALYSIS OF LIPOOLIGOSACCHARIDE PRODUCED BY NEISSERIA-GONORRHOEAE, STRAIN MS11MK (VARIANT-A) - A PRECURSOR FOR A GONOCOCCAL LIPOOLIGOSACCHARIDE ASSOCIATED WITH VIRULENCE SO BIOCHEMISTRY LA English DT Article ID MONOSACCHARIDE ANALYSIS; MONOCLONAL-ANTIBODIES; EPITOPE EXPRESSION; HUMAN-ERYTHROCYTES; LOS; LIPOPOLYSACCHARIDES; OLIGOSACCHARIDES; CHROMATOGRAPHY; IDENTIFICATION; HETEROGENEITY AB We studied the structure of the lipooligosaccharide (LOS) that is produced by a variant A of strain MS11mk. This variant produces a single LOS that is recognized by monoclonal antibody (MAb) 2-1-L8. In a recent study of the pathogenesis of Neisseria gonorrhoeae in male volunteers, variant A gave rise to other phase variants that produce higher molecular weight LOSs, and these LOS were associated with virulence. Definition of the structure of the variant A LOS is important to understand the biosynthesis of LOS and its expression in vivo. The dephosphorylated oligosaccharide (OS) structure derived from the variant A LOS was analyzed by two-dimensional NMR and methylation analysis. The OS structure was found to be a truncated form of the LOS produced by strain F62 [Yamasaki et al. (1991) Biochemistry 30, 10566-10575]; the variant A OS is a hexamer, a beta-lactosyl residue linked to a tetrasaccharide: Galbeta1-->4Glcbeta1-->4{GlcNAcalpha1-->2Hepalpha1-->3}Hepalpha1-->KDO. We determined that the variant A LOS is a precursor for the synthesis of higher MW LOS. We also studied expression of the MAb 2-1-L8-defined epitope present on the variant A LOS. Our data indicate that the MAb-defined epitope is not a linear beta-lactosyl residue but its specificity is directed toward the phosphorylated GlcNAc-Hep-Hep residue. Since this MAb binds to gonococci, at least part of the phosphorylated diheptose area is exposed on the gonococcal surface. C1 UNIV CALIF SAN FRANCISCO,CTR IMMUNOCHEM,SAN FRANCISCO,CA 94143. UNIV CALIF SAN FRANCISCO,DEPT LAB MED,SAN FRANCISCO,CA 94143. VET ADM MED CTR,SAN FRANCISCO,CA 94121. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. FU NIAID NIH HHS [AI 22998] NR 36 TC 41 Z9 41 U1 0 U2 1 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0006-2960 J9 BIOCHEMISTRY-US JI Biochemistry PD DEC 29 PY 1992 VL 31 IS 51 BP 12760 EP 12768 DI 10.1021/bi00166a008 PG 9 WC Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA KE606 UT WOS:A1992KE60600008 PM 1281427 ER PT J AU WU, JJ AF WU, JJ TI A GENERALIZED HARMONIC-BALANCE METHOD FOR FORCED NONLINEAR OSCILLATIONS - THE SUBHARMONIC CASES SO JOURNAL OF SOUND AND VIBRATION LA English DT Article ID SYSTEMS RP WU, JJ (reprint author), USA,RES OFF,RES TRIANGLE PK,NC 27709, USA. NR 18 TC 5 Z9 5 U1 3 U2 3 PU ACADEMIC PRESS LTD PI LONDON PA 24-28 OVAL RD, LONDON, ENGLAND NW1 7DX SN 0022-460X J9 J SOUND VIB JI J. Sound Vibr. PD DEC 22 PY 1992 VL 159 IS 3 BP 503 EP 525 DI 10.1016/0022-460X(92)90755-M PG 23 WC Acoustics; Engineering, Mechanical; Mechanics SC Acoustics; Engineering; Mechanics GA KE314 UT WOS:A1992KE31400007 ER PT J AU LI, YJ GAO, T LIU, J LINLIU, K DESPER, CR CHU, B AF LI, YJ GAO, T LIU, J LINLIU, K DESPER, CR CHU, B TI MULTIPHASE STRUCTURE OF A SEGMENTED POLYURETHANE - EFFECTS OF TEMPERATURE AND ANNEALING SO MACROMOLECULES LA English DT Article ID X-RAY-SCATTERING; INDUCED MORPHOLOGICAL-CHANGES; ENDOTHERMIC BEHAVIOR; BLOCK POLYMERS; SYNCHROTRON RADIATION; ELASTOMERS; DSC; COPOLYMERS AB The multiphase structure and related relaxations of a segmented polyurethane were characterized by using a combination of differential scanning calorimetry (DSC) and synchrotron small-angle X-ray scattering (SAXS). The results showed a soft-segment glass transition temperature (T(g,s)) which is significantly higher than the T(g,s) (-84-degrees-C) of the corresponding pure soft segment, suggesting an incomplete phase-separation behavior for the soft segment. The specimen lost its mechanical strength at above 200-degrees-C while DSC indicated an endotherm at approximately 195-degrees-C due to the hard-segment domain dissolution into the soft-segment matrix. Synchrotron SAXS scanning from 26 to 250-degrees-C indicated that the sample structure remained stable with increasing temperature. A small change around 75-degrees-C was attributed to the glass transition of the amorphous hard-segment domain. Phase mixing took place when the temperature was above 190-degrees-C, in agreement with the DSC results. Synchrotron SAXS was also used to study the postannealing effects on the segmented polyurethane with a well-defined thermal history. The structural changes were irreversible upon annealing. Thermal postannealing did not have a significant effect on the multiphase structure once the structure development had reached equilibrium and interactions among the hard segments had reached a certain degree of strength. However, postannealing could promote perfection inside the hard-segment domain or further phase separation of some hard segments inside the soft-segment matrix. The structures from the samples which have not reached equilibrium or have very weak interactions among the hard segments could be changed dramatically by postannealing. The only way to change the existing structure entirely is to melt the sample. Although the phase-separation process in the segmented polyurethane was very slow, the phase mixing at high temperatures was extremely fast. Based on the Koberstein-Stein coiling/folding hard-segment model, a temperature- and interaction-dependent coiled hard-segment model could be used to interpret our observations. The mobility of the hard segment, the viscosity of the system, and the interaction between the hard segments are three key factors which control the structure in segmented polyurethanes. C1 SUNY STONY BROOK,DEPT MAT SCI & ENGN,STONY BROOK,NY 11794. USA,MAT TECHNOL LAB,WATERTOWN,MA 02172. RP LI, YJ (reprint author), SUNY STONY BROOK,DEPT CHEM,STONY BROOK,NY 11794, USA. RI He, Yong/F-8752-2012 NR 32 TC 85 Z9 89 U1 3 U2 16 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0024-9297 J9 MACROMOLECULES JI Macromolecules PD DEC 21 PY 1992 VL 25 IS 26 BP 7365 EP 7372 DI 10.1021/ma00052a045 PG 8 WC Polymer Science SC Polymer Science GA KE277 UT WOS:A1992KE27700045 ER PT J AU WRABACK, M TAUC, J AF WRABACK, M TAUC, J TI DIRECT MEASUREMENT OF THE HOT CARRIER COOLING RATE IN A-SI-H USING FEMTOSECOND-4 EV PULSES SO PHYSICAL REVIEW LETTERS LA English DT Article ID AMORPHOUS-SILICON; ABSORPTION; SYSTEMS; GAAS; THERMALIZATION; SPECTROSCOPY; TRANSMISSION; DEPENDENCE AB We report the first direct measurement of the hot carrier cooling rate in a-Si:H. The femtosecond pump and probe technique with both 2 and 4 eV pulses was used to generate and probe directly hot carriers with considerable excess energy in the extended states of this material. The unexpectedly large average energy dissipation rate of 2 eV/psec obtained from our experiments suggests that disorder-enhanced carrier-phonon interactions may play an important role in the cooling process. C1 BROWN UNIV,DEPT PHYS,PROVIDENCE,RI 02912. BROWN UNIV,DIV ENGN,PROVIDENCE,RI 02912. RP WRABACK, M (reprint author), USA,SLCET ED,FT MONMOUTH,NJ 07703, USA. NR 26 TC 15 Z9 15 U1 0 U2 4 PU AMERICAN PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0031-9007 J9 PHYS REV LETT JI Phys. Rev. Lett. PD DEC 21 PY 1992 VL 69 IS 25 BP 3682 EP 3685 DI 10.1103/PhysRevLett.69.3682 PG 4 WC Physics, Multidisciplinary SC Physics GA KC931 UT WOS:A1992KC93100023 ER PT J AU BROZENA, A FIELDER, D AF BROZENA, A FIELDER, D TI SUBAMBIENT APPLICATIONS OF DIFFERENTIAL THERMAL-ANALYSIS FOR THE DETERMINATION OF VAPOR-PRESSURE SO THERMOCHIMICA ACTA LA English DT Article; Proceedings Paper CT 20TH CONF OF THE NORTH AMERICAN THERMAL ANALYSIS SOC : NEW DIRECTIONS IN MATERIAL CHARACTERIZATION BY THERMAL ANALYSIS CY SEP 20-26, 1991 CL MINNEAPOLIS, MN SP N AMER THERMAL ANAL SOC AB Differential thermal analysis (DTA) has been shown to be a useful technique for determining the vapor pressure of pure liquids. Incorporation of a subambient cooling accessory into existing commercial instrumentation allows rapid determination (in less than 2 h) of vapor pressure curves of pure liquids over wide pressure (5-760 Torr) and temperature (- 180-450-degrees-C) ranges using a small amount (less than 1 ml) of sample. Vapor pressure curves of several compounds, for which only atmospheric pressure boiling points were available, have been established with this technique. RP BROZENA, A (reprint author), USA,ARMY CHEM RES,CTR DEV & ENGN,ABERDEEN PROVING GROUND,MD 21010, USA. NR 7 TC 2 Z9 2 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0040-6031 J9 THERMOCHIM ACTA JI Thermochim. Acta PD DEC 21 PY 1992 VL 212 BP 63 EP 68 DI 10.1016/0040-6031(92)80220-Q PG 6 WC Thermodynamics; Chemistry, Analytical; Chemistry, Physical SC Thermodynamics; Chemistry GA KJ946 UT WOS:A1992KJ94600008 ER PT J AU KLEIN, N LEVERITT, CS AF KLEIN, N LEVERITT, CS TI COMBUSTION OF LIQUID GUN PROPELLANTS IN AN ADIABATIC CALORIMETER SO THERMOCHIMICA ACTA LA English DT Article; Proceedings Paper CT 20TH CONF OF THE NORTH AMERICAN THERMAL ANALYSIS SOC : NEW DIRECTIONS IN MATERIAL CHARACTERIZATION BY THERMAL ANALYSIS CY SEP 20-26, 1991 CL MINNEAPOLIS, MN SP N AMER THERMAL ANAL SOC AB An accelerating rate calorimeter (ARC) was used to evaluate the effect of chemical composition on the thermal stability and burning rate of the liquid propellants currently being considered for use in medium-to-large caliber guns. The most effective propellants to date have been stoichiometric, aqueous mixtures of hydroxylammonium nitrate (HAN) and the nitrate salt of an organic amine, triethanolammonium nitrate (TEAN). Because these propellants do not burn at atmospheric pressure, but instead react slowly enough to maintain thermal pseudo-equilibrium, such experiments provide information regarding the stability of the mixtures in storage. Thermal stability is directly related to the nitrate ion concentration of the mixtures, and propellant composition can be modified to change energy release rates without affecting thermal stability. Replacement of the TEAN component with N,N-diethylhydroxylammonium nitrate (DEHAN) increases burning rate as much as 17-fold without adversely affecting thermal stability because the total nitrate concentration of the HAN-TEAN and HAN-DEHAN mixtures is the same. RP KLEIN, N (reprint author), USA,BALLIST RES LABS,DIV INTERIOR BALLIST,ABERDEEN PROVING GROUND,MD 21005, USA. NR 7 TC 0 Z9 0 U1 2 U2 3 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0040-6031 J9 THERMOCHIM ACTA JI Thermochim. Acta PD DEC 21 PY 1992 VL 212 BP 97 EP 103 DI 10.1016/0040-6031(92)80224-K PG 7 WC Thermodynamics; Chemistry, Analytical; Chemistry, Physical SC Thermodynamics; Chemistry GA KJ946 UT WOS:A1992KJ94600012 ER PT J AU DESCHAMPS, BJ LAWLESS, DE CARR, FE WONG, NCW AF DESCHAMPS, BJ LAWLESS, DE CARR, FE WONG, NCW TI RAT HEPATONUCLEAR FACTOR PS-1 REGULATES TISSUE-SPECIFIC ACTIVITY OF THE S14 PROMOTER INVITRO SO JOURNAL OF BIOLOGICAL CHEMISTRY LA English DT Article ID HEPATIC GENE-EXPRESSION; HORMONE-RESPONSIVE GENE; THYROID-HORMONE; MESSENGER-RNA; ALBUMIN PROMOTER; BINDING PROTEINS; TRANSCRIPTION; LIVER; DNA; BOX AB We have previously identified a rat hepatonuclear factor, PS-1 that binds to the thyroid hormone responsive gene, S14. To determine whether PS-1 is involved in regulating tissue-specific expression of the S14 gene, we have correlated the DNA binding activity of PS-1 with mRNA-S14 expression in a variety of tissues. Gel retardation analysis revealed a pattern of binding to the recognition site that was characteristic of tissues with high levels of mRNA-S14, a different pattern was found in tissues which do not express the gene. Competition studies using mutant oligonucleotides showed that the first 4 nucleotides and the CAAT motif contained within the PS-1 recognition sequence are essential for protein binding. C/EBP, a CCAAT-transcription factor binds to the PS-1 recognition site thus raising the possibility that both C/EBP and PS-1 may belong to the same family of proteins. Next we used a cell-free transcription assay to measure activity of a template, pS14-GFC(-72), that contained the PS-1 sequence. The pS14-GFC(-72) template was active in hepatonuclear extracts but deletion of or competition with the PS-1 binding sequence rendered the construct inactive. A template containing three PS-1 binding sequences increased S14 promoter activity by 12- to 13-fold. In nuclear extracts from spleen and testis, relative S14 promoter activity was only 2% of that in the liver, this observation mimicked closely in vivo expression of the gene. Mixing together extracts from liver and spleen in varying proportions, prior to incubation with S14 template, yielded a linear increase in S14 promoter activity that correlated with the amount of liver extract in the reaction. This finding is consistent with the absence of an essential factor or factors in spleen that is/are required for S14 promoter activity in vitro. In summary, PS-1 binds to a DNA sequence that contains a CAAT motif and appears to play a critical role in determining tissue-specific activity of the S14 promoter in vitro. C1 UNIV CALGARY,HLTH SCI CTR,FAC MED,DEPT MED,3330 HOSP DR NW,CALGARY T2N 4N1,ALBERTA,CANADA. WALTER REED ARMY MED CTR,KYLE METAB UNIT,WASHINGTON,DC 20307. UNIV CALGARY,DEPT MED BIOCHEM,CALGARY T2N 4N1,ALBERTA,CANADA. NR 35 TC 7 Z9 7 U1 0 U2 0 PU AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 0021-9258 J9 J BIOL CHEM JI J. Biol. Chem. PD DEC 15 PY 1992 VL 267 IS 35 BP 25167 EP 25171 PG 5 WC Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA KB603 UT WOS:A1992KB60300040 PM 1460016 ER PT J AU WADHAMS, P TUCKER, WB KRABILL, WB SWIFT, RN COMISO, JC DAVIS, NR AF WADHAMS, P TUCKER, WB KRABILL, WB SWIFT, RN COMISO, JC DAVIS, NR TI RELATIONSHIP BETWEEN SEA ICE FREEBOARD AND DRAFT IN THE ARCTIC BASIN, AND IMPLICATIONS FOR ICE THICKNESS MONITORING SO JOURNAL OF GEOPHYSICAL RESEARCH-OCEANS LA English DT Article ID CLASSIFICATION; SUBMARINE; SONAR AB We have confirmed our earlier finding that the probability density function (pdf) of ice freeboard in the Arctic Ocean can be converted to a pdf of ice draft by applying a simple coordinate transformation based on the measured mean draft and mean elevation. This applies in each of six 50-km sections (north of Greenland) of joint airborne laser and submarine sonar profile obtained along nearly coincident tracks from the Arctic Basin north of Greenland and tested for this study. Detailed differences in the shape of the pdf can be explained on the basis of snow load and can, in principle, be compensated by the use of-a more sophisticated freeboard-dependent transformation. The measured ''density ratio'' R (actually mean draft/mean elevation ratio) for each section was found to be consistent over all sections tested, despite differences in the ice regime, indicating that a single value of R might be used for measurements done in this season of the year. The mean value [R] from all six sections is 7.89; on the assumption that all six values are drawn from the same population, the standard deviation is 0.55 for a single 50-km section, and thus 0.22 for 300 km of track. In attempting to infer ice draft from laser-measured freeboard, we would therefore expect an accuracy of about +/- 28 cm in 50 km of track (if mean draft is about 4 m) and about +/- 11 cm in 300 km of track; these accuracies are compatible with the resolution of predictions from numerical models. A simple model for the variability of R with season and with mean ice thickness gives results in reasonable agreement with observations. They show that although there is a large seasonal variability due to snow load, there is a stable period from November to April when the variability is chiefly dependent on the mean ice thickness alone. Thus, in principle, R can be mapped over the Arctic Ocean as a basis for interpreting survey data. Better field data are needed on the seasonal and spatial variability of three key quantities: area-averaged snow load, mean density of first-year and multiyear ice (including the effect of ridging with these two ice regimes), and density of near-surface water. C1 NASA,GODDARD SPACE FLIGHT CTR,WALLOPS FLIGHT FACIL,HYDROSPHER,WALLOPS ISL,VA. NASA,GODDARD SPACE FLIGHT CTR,EG&G WASHINGTON ANALYT,WALLOPS FLIGHT FACIL,WALLOPS ISL,VA. USA,CORPS ENGN,COLD REGIONS RES & ENGN LAB,HANOVER,NH 03755. NASA,GODDARD SPACE FLIGHT CTR,HYDROSPHER PROC LAB,GREENBELT,MD 20771. RP WADHAMS, P (reprint author), UNIV CAMBRIDGE,SCOTT POLAR RES INST,LENSFIELD RD,CAMBRIDGE CB2 1ER,ENGLAND. NR 41 TC 55 Z9 55 U1 0 U2 1 PU AMER GEOPHYSICAL UNION PI WASHINGTON PA 2000 FLORIDA AVE NW, WASHINGTON, DC 20009 SN 0148-0227 J9 J GEOPHYS RES-OCEANS JI J. Geophys. Res.-Oceans PD DEC 15 PY 1992 VL 97 IS C12 BP 20325 EP 20334 DI 10.1029/92JC02014 PG 10 WC Oceanography SC Oceanography GA KE656 UT WOS:A1992KE65600017 ER PT J AU GOMPPER, G KROLL, DM AF GOMPPER, G KROLL, DM TI SHAPE OF INFLATED VESICLES SO PHYSICAL REVIEW A LA English DT Article ID SELF-AVOIDING SURFACES; MONTE-CARLO; UNIVERSAL FEATURES; FLUID MEMBRANES; ELASTICITY; DIMENSIONS; BEHAVIOR; POLYMERS; TENSION AB The conformation and scaling properties of self-avoiding fluid vesicles with zero extrinsic bending rigidity subject to an internal pressure increment DELTAp > 0 are studied using Monte Carlo methods and scaling arguments. With increasing pressure, there is a first-order transition from a collapsed branched polymer phase to an extended inflated phase. The scaling behavior of the radius of gyration, the asphericities, and several other quantities characterizing the average shape of a vesicle are studied in detail. In the inflated phase, continuously variable fractal shapes are found to be controlled by the scaling variable x = DELTApN3nu/2 (or, equivalently, y = [V]/N3nu/2), where N is the number of monomers in the vesicle and V the enclosed volume. The scaling behavior in the inflated phase is described by a new exponent nu=0.787+/-0.02. C1 UNIV MINNESOTA, ARMY HIGH PERFORMANCE COMP RES CTR, MINNEAPOLIS, MN 55415 USA. RP GOMPPER, G (reprint author), UNIV MUNICH, SEKT PHYS, THERESIEN STR 37, W-8000 MUNICH 2, GERMANY. RI Gompper, Gerhard/I-4886-2012 OI Gompper, Gerhard/0000-0002-8904-0986 NR 33 TC 22 Z9 22 U1 1 U2 2 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 1050-2947 EI 1094-1622 J9 PHYS REV A JI Phys. Rev. A PD DEC 15 PY 1992 VL 46 IS 12 BP 7466 EP 7473 DI 10.1103/PhysRevA.46.7466 PG 8 WC Optics; Physics, Atomic, Molecular & Chemical SC Optics; Physics GA KE871 UT WOS:A1992KE87100021 ER PT J AU SCHAUER, SN WILLIAMS, P AF SCHAUER, SN WILLIAMS, P TI DOUBLY CHARGED SPUTTERED IONS OF 4TH-ROW ELEMENTS SO PHYSICAL REVIEW B LA English DT Article ID 3D TRANSITION-METALS; AUGER-SPECTRA; COSTER-KRONIG; FLUORESCENCE YIELDS; MASS-SPECTROMETRY; ENERGY-SPECTRA; SECONDARY IONS; SHELL AUGER; EMISSION; RATES AB We have measured the initial-kinetic-energy distributions of sputtered doubly charged ions of the fourth-row elements (Ca-As) over a range 0-1000 eV and energy distributions of singly charged ions 0-500 eV. The energy distributions of the doubly charged ions lack the characteristic low-energy peak exhibited by most sputtered ions, and some actually have peak intensities at high energy. Oxygen enhances the doubly charged ion yields of Sc2+-Ni2+ and alters the energy distributions of these ions, increasing the proportion of low-energy ions, but either does not affect or suppresses ion yields from Ca2+ and Cu2+-As2+. These results can be explained in terms of the kinetic emission model, in which an atom sputtered with a core-level vacancy resulting from an energetic collision has a finite probability, dependent on the atom velocity and the vacancy lifetime, of undergoing Auger deexcitation far enough from the surface for the resulting multiply charged ion to survive. The effect of oxygen is interpreted as a lengthening of the vacancy lifetime due to electron withdrawal from the cations in an oxygenated lattice. C1 ARIZONA STATE UNIV,DEPT CHEM,TEMPE,AZ 85287. RP SCHAUER, SN (reprint author), USA,ELECTR TECHNOL & DEVICES LAB,SLCET EP,FT MONMOUTH,NJ 07703, USA. NR 40 TC 28 Z9 28 U1 0 U2 1 PU AMERICAN PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0163-1829 J9 PHYS REV B JI Phys. Rev. B PD DEC 15 PY 1992 VL 46 IS 23 BP 15452 EP 15464 DI 10.1103/PhysRevB.46.15452 PG 13 WC Physics, Condensed Matter SC Physics GA KG306 UT WOS:A1992KG30600061 ER PT J AU CRENSHAW, ME BOWDEN, CM AF CRENSHAW, ME BOWDEN, CM TI QUASI-ADIABATIC FOLLOWING APPROXIMATION FOR A DENSE MEDIUM OF 2-LEVEL ATOMS SO PHYSICAL REVIEW LETTERS LA English DT Article ID VAPOR AB An adiabaticlike approximation is derived for the optical Bloch equations, extended for dense media, and used to interpret recent numerical results for the resonant interaction of ultrashort pulses with dense media. It is shown that dense media can exhibit behavior analogous to adiabatic following and adiabatic inversion. In particular, we show that dense collections of two-level systems can be adiabatically inverted by intrinsic self-chirping. RP CRENSHAW, ME (reprint author), USA,MISSILE COMMAND,CTR RES DEV & ENGN,AMSMI RD WS,WEAPONS SCI DIRECTORATE,REDSTONE ARSENAL,AL 35898, USA. NR 18 TC 36 Z9 37 U1 0 U2 0 PU AMERICAN PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0031-9007 J9 PHYS REV LETT JI Phys. Rev. Lett. PD DEC 14 PY 1992 VL 69 IS 24 BP 3475 EP 3478 DI 10.1103/PhysRevLett.69.3475 PG 4 WC Physics, Multidisciplinary SC Physics GA KB857 UT WOS:A1992KB85700015 ER PT J AU ALVING, CR AF ALVING, CR TI IMMUNOLOGICAL ASPECTS OF LIPOSOMES - PRESENTATION AND PROCESSING OF LIPOSOMAL PROTEIN AND PHOSPHOLIPID ANTIGENS SO BIOCHIMICA ET BIOPHYSICA ACTA LA English DT Review ID CYTOTOXIC LYMPHOCYTES-T; CLASS-II MHC; SPHINGOMYELIN-CONTAINING LIPOSOMES; RECOGNIZE PHOSPHATIDYL CHOLINE; NATURALLY-OCCURRING ANTIBODIES; SUPPORTED PLANAR MEMBRANES; PURIFIED HLA-A; ACCESSORY CELLS; IMMUNE-RESPONSE; B-CELLS RP ALVING, CR (reprint author), WALTER REED ARMY INST RES,DEPT MEMBRANE BIOCHEM,WASHINGTON,DC 20307, USA. NR 182 TC 82 Z9 87 U1 0 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0006-3002 J9 BIOCHIM BIOPHYS ACTA PD DEC 11 PY 1992 VL 1113 IS 3-4 BP 307 EP 322 DI 10.1016/0304-4157(92)90004-T PG 16 WC Biochemistry & Molecular Biology; Biophysics SC Biochemistry & Molecular Biology; Biophysics GA KD463 UT WOS:A1992KD46300004 PM 1450204 ER PT J AU ELSON, HF GENTRY, MK DOCTOR, BP AF ELSON, HF GENTRY, MK DOCTOR, BP TI MEMBRANE-BOUND ACETYLCHOLINESTERASE - AN EARLY DIFFERENTIATION MARKER FOR SKELETAL MYOBLASTS SO BIOCHIMICA ET BIOPHYSICA ACTA LA English DT Article DE ACETYLCHOLINESTERASE; CELL CULTURE; CHICK EMBRYO; FIBROBLAST; MYOGENESIS; PLASMA MEMBRANE; SKELETAL MUSCLE ID MOLECULAR-FORMS; MONOCLONAL-ANTIBODIES; MUSCLE AB Cell-bound acetylcholinesterase (AChE) was found to be an early differentiation marker on embryonic chick skeletal myoblasts in mixed primary cell cultures. AChE biosynthesis was detected and characterized by (a) a sensitive microtiter assay, (b) use of selective inhibitors, and (c) with mono- and polyclonal antibodies. Both secreted and cell-bound AChE appeared on the first day in culture, at a time when no muscle cell fusion was observed. Characterization of this enzyme revealed that true AChE was bound and secreted by myoblasts. BW284c51, which permeates cell membranes poorly, inhibited all the cell-associated AChE activity on myoblasts, suggesting that the activity measured was on the outer cell surface. On the other hand, fibroblasts appeared to have no or very little bound enzyme and the low level of secreted enzyme activity had the characteristics of pseudo-, or butyrylcholinesterase. Polyclonal anti-Torpedo californica electroplax AChE antibody and several monoclonal antibodies were found to bind specifically to chick myoblasts. Since the cells had not been made permeable before antibody binding, a membrane-bound form of the enzyme was most likely being detected. The cell-bound true AChE was present in identifiable quantities from the first day of culture. Membrane-bound AChE can thus serve as an early differentiation marker for embryonic chick myoblasts in mixed primary cultures. C1 WALTER REED ARMY INST RES, DEPT BIOL CHEM, DIV BIOCHEM, WASHINGTON, DC 20307 USA. NR 35 TC 4 Z9 4 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0006-3002 J9 BIOCHIM BIOPHYS ACTA JI Biochim. Biophys. Acta PD DEC 8 PY 1992 VL 1156 IS 1 BP 78 EP 84 DI 10.1016/0304-4165(92)90099-G PG 7 WC Biochemistry & Molecular Biology; Biophysics SC Biochemistry & Molecular Biology; Biophysics GA KE832 UT WOS:A1992KE83200013 PM 1472543 ER PT J AU SCALORA, M BOWDEN, CM HAUS, JW AF SCALORA, M BOWDEN, CM HAUS, JW TI MACROSCOPIC QUANTUM FLUCTUATIONS IN HIGH-GAIN OPTICAL AMPLIFIERS SO PHYSICAL REVIEW LETTERS LA English DT Article ID STIMULATED RAMAN-SCATTERING; SPONTANEOUS INITIATION; SPONTANEOUS GENERATION; NOISE; SUPERFLUORESCENCE; PROPAGATION; TRANSIENT; SOLITONS; BUILDUP; DECAY AB We use numerical methods to investigate stochastic and coherence properties of the fields transverse profiles in stimulated Raman scattering. In the linear regime with diffractive coupling, the amplified signal is characterized by fluctuations that are macroscopic. We find an interesting dependence of the beam-pointing fluctuations on photon conversion efficiency. Our results for the linear regime compare well with recent experiments, and we report an increase in beam-pointing fluctuations in the nonlinear regime. We discuss the results of modeling with one and two transverse dimensions. C1 UNIV TOKYO, ADV SCI & TECHNOL RES CTR, MEGURO KU, TOKYO 153, JAPAN. RENSSELAER POLYTECH INST, DEPT PHYS, TROY, NY 12180 USA. RP USA, MISSILE RES & DEV COMMAND, WEAPONS SCI DIRECTORATE, AMSMI RD WS ST, RES DEV & ENGN CTR, REDSTONE ARSENAL, AL 35898 USA. NR 27 TC 3 Z9 3 U1 0 U2 0 PU AMER PHYSICAL SOC PI COLLEGE PK PA ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA SN 0031-9007 EI 1079-7114 J9 PHYS REV LETT JI Phys. Rev. Lett. PD DEC 7 PY 1992 VL 69 IS 23 BP 3310 EP 3313 DI 10.1103/PhysRevLett.69.3310 PG 4 WC Physics, Multidisciplinary SC Physics GA KB203 UT WOS:A1992KB20300011 ER PT J AU CALLAHAN, HL BEVERLEY, SM AF CALLAHAN, HL BEVERLEY, SM TI A MEMBER OF THE ALDOKETO REDUCTASE FAMILY CONFERS METHOTREXATE RESISTANCE IN LEISHMANIA SO JOURNAL OF BIOLOGICAL CHEMISTRY LA English DT Note ID DIHYDROFOLATE-REDUCTASE; ALCOHOL-DEHYDROGENASE; PROSTAGLANDIN ACTION; NUCLEOTIDE-SEQUENCE; NITROGEN-FIXATION; 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE; TETRAHYDROBIOPTERIN BIOSYNTHESIS; EXTRACHROMOSOMAL CIRCLES; THYMIDYLATE SYNTHASE; DNA AMPLIFICATION AB Methotrexate (MTX)-resistant mutants of the parasitic protozoan Leishmania have been used as models for the mechanism and genetic basis of drug resistance in trypanosomatids and other cells. Three resistance mechanisms to MTX, a dihydrofolate reductase inhibitor, have been described in Leishmania: decreased uptake and accumulation of MTX via the folate/MTX transporter, amplification and overexpression of the dihydrofolate reductase-thymidylate synthase gene, and extrachromosomal amplification of H region DNA. We have now identified hmtx(r) as the H region gene conferring MTX resistance using a transfection-based approach. Data base searches show that the predicted HMTX(r) protein is related to members of the polyol dehydrogenase/carbonyl reductase family of aldoketo reductases, whose substrates include polyols, quinones, steroids, prostaglandins, fatty acids, and pterins. We therefore propose that HMTX(r) is also an oxidoreductase and suggest several biochemical mechanisms of resistance in Leishmania that could be exploited in the design of parasite-specific inhibitors. C1 HARVARD UNIV,SCH MED,DEPT BIOL CHEM & MOLEC PHARMACOL,BOSTON,MA 02115. RP CALLAHAN, HL (reprint author), WALTER REED ARMY MED CTR,WALTER REED ARMY INST RES,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307, USA. OI Beverley, Stephen/0000-0001-5319-0811 FU NIAID NIH HHS [AI 21903] NR 41 TC 88 Z9 91 U1 0 U2 1 PU AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 0021-9258 J9 J BIOL CHEM JI J. Biol. Chem. PD DEC 5 PY 1992 VL 267 IS 34 BP 24165 EP 24168 PG 4 WC Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA KA263 UT WOS:A1992KA26300005 PM 1339441 ER PT J AU HUANG, TC SIMONIS, GJ COLDREN, LA AF HUANG, TC SIMONIS, GJ COLDREN, LA TI DIRECTIONAL COUPLER OPTICAL SWITCH CONSTRUCTED FROM FIELD-INDUCED WAVE-GUIDES SO ELECTRONICS LETTERS LA English DT Article DE OPTICAL SWITCHING; DIRECTIONAL COUPLERS; OPTICAL WAVE-GUIDE AB A novel directional-coupler optical switch based on the concept of the field-induced guide is demonstrated for the first time. The device exhibits a good switching characteristic between two output ends with a crosstalk of -10 dB at a 1-15 mum wavelength for a device with an 800 mum coupling length. C1 UNIV CALIF SANTA BARBARA,DEPT ELECT & COMP ENGN,SANTA BARBARA,CA 93106. RP HUANG, TC (reprint author), USA,RES LAB,ADELPHI,MD 20783, USA. NR 4 TC 10 Z9 11 U1 0 U2 0 PU IEE-INST ELEC ENG PI HERTFORD PA MICHAEL FARADAY HOUSE SIX HILLS WAY STEVENAGE, HERTFORD, ENGLAND SG1 2AY SN 0013-5194 J9 ELECTRON LETT JI Electron. Lett. PD DEC 3 PY 1992 VL 28 IS 25 BP 2288 EP 2289 DI 10.1049/el:19921472 PG 2 WC Engineering, Electrical & Electronic SC Engineering GA KD325 UT WOS:A1992KD32500016 ER PT J AU GLASS, AR AF GLASS, AR TI PHARMACEUTICAL ADVERTISING IN THE JOURNAL SO NEW ENGLAND JOURNAL OF MEDICINE LA English DT Letter RP GLASS, AR (reprint author), WALTER REED ARMY MED CTR,WASHINGTON,DC 20307, USA. NR 1 TC 1 Z9 1 U1 0 U2 0 PU MASS MEDICAL SOC PI BOSTON PA 10 SHATTUCK, BOSTON, MA 02115 SN 0028-4793 J9 NEW ENGL J MED JI N. Engl. J. Med. PD DEC 3 PY 1992 VL 327 IS 23 BP 1688 EP 1688 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA KA260 UT WOS:A1992KA26000026 PM 1435911 ER PT J AU BURRIS, HA HANAUSKE, AR JOHNSON, RK MARSHALL, MH KUHN, JG HILSENBECK, SG VONHOFF, DD AF BURRIS, HA HANAUSKE, AR JOHNSON, RK MARSHALL, MH KUHN, JG HILSENBECK, SG VONHOFF, DD TI ACTIVITY OF TOPOTECAN, A NEW TOPOISOMERASE-I INHIBITOR, AGAINST HUMAN TUMOR COLONY-FORMING-UNITS INVITRO SO JOURNAL OF THE NATIONAL CANCER INSTITUTE LA English DT Article ID NSC-100880 AB Background: Topotecan [(S)-9-dimethylaminomethyl(10-hydroxycamptothecin), NSC 609699, SK&F 104864A], a semisynthetic analogue of the natural product camptothecin, is a cell cycle-specific drug that exerts antineoplastic activity through inhibition of topoisomerase I. Currently, topotecan is undergoing phase I and early phase II clinical trials. The dose-limiting toxicity for topotecan is myelosuppression. Purpose: Our purpose was to determine plasma concentrations and exposure times necessary for optimal clinical activity and tumor types that may be responsive in phase II clinical studies of topotecan. Methods: A soft-agar cloning system assay was used to determine the in vitro effects of topotecan against cells from biopsy specimens of colorectal, breast, lung, ovarian, renal cell, and gastric cancers and cancers of unknown primary origin. We studied 141 freshly explanted tumor specimens, using 1-hour exposure to topotecan, and 80 were studied using continuous exposure. A decrease in tumor colony formation resulting from drug exposure was considered an in vitro response if survival of colonies was up to 50% of that in controls. Results: With 1-hour exposure, in vitro responses were seen in 10% and 25% of assessable tumor specimens at final topotecan concentrations of 1.0 and 10.0 mug/mL, respectively. With continuous exposures at concentrations of 0.1 and 1.0 mug/mL, in vitro response rates were 34% and 76%, respectively. Specific activity was seen against colorectal, breast, non-small-cell lung, ovarian, and renal cell cancers, with responses observed in 27%, 25%, 32%, 39%, and 83%, respectively, of assessable tumor specimens after continuous exposure to 0.1 mug/mL topotecan. A subset of tumor specimens resistant to doxorubicin or fluorouracil was sensitive to topotecan, and the difference in sensitivity was statistically significant. In addition, some of the tumor specimens resistant to cyclophosphamide and etoposide were also sensitive to topotecan. Conclusions: Topotecan appears to be active in vitro against a variety of human tumors, including a subgroup resistant in vitro to standard antineoplastic agents. If plasma levels of 0.1 mug/mL can be achieved for prolonged periods of time in ongoing clinical trials, topotecan should have substantial clinical activity. Implications: Further clinical development of topotecan is warranted. C1 UNIV TEXAS,HLTH SCI CTR,DEPT MED,DIV ONCOL,7703 FLOYD CURL DR,SAN ANTONIO,TX 78284. TECH UNIV MUNICH,KLINIKUM RECHTS ISAR,HAMATOL & ONKOL ABT,W-8000 MUNICH 80,GERMANY. BROOKE ARMY MED CTR,HEMATOL ONCOL SERV,FT SAM HOUSTON,TX 78234. SMITHKLINE BEECHAM PHARMACEUT,KING OF PRUSSIA,PA. CANC THERAPY & RES FDN S TEXAS,SAN ANTONIO,TX. NR 14 TC 148 Z9 149 U1 2 U2 6 PU NATL CANCER INSTITUTE PI BETHESDA PA 9030 OLD GEORGETOWN RD, BETHESDA, MD 20814 SN 0027-8874 J9 J NATL CANCER I JI J. Natl. Cancer Inst. PD DEC 2 PY 1992 VL 84 IS 23 BP 1816 EP 1820 DI 10.1093/jnci/84.23.1816 PG 5 WC Oncology SC Oncology GA JZ628 UT WOS:A1992JZ62800012 PM 1331485 ER PT J AU RUBIOPALIS, Y WIRTZ, RA CURTIS, CF AF RUBIOPALIS, Y WIRTZ, RA CURTIS, CF TI MALARIA ENTOMOLOGICAL INOCULATION RATES IN WESTERN VENEZUELA SO ACTA TROPICA LA English DT Article DE ANOPHELES SPP; MALARIA; ELISA; VENEZUELA ID LINKED IMMUNOSORBENT-ASSAY; PLASMODIUM-FALCIPARUM; CIRCUMSPOROZOITE PROTEIN; AFROTROPICAL ANOPHELES; MICROTITRATION PLATES; THERMAL-GRADIENTS; CULICIDAE; MOSQUITOS; DIPTERA; ELISA AB Over 61 000 anophelines collected between January 1988 and October 1989 in three villages in western Venezuela were assayed by ELISA for Plasmodium vivax circumsporozoite (CS) protein. The six specimens confirmed positive belonged to three species: Anopheles (Nyssorhynchus) nuneztovari Gabaldon, 1940, A. albitarsis Arribalzaga, 1878 sensu lato and A. oswaldoi (Peryassu, 1922). The estimated CS protein rate for all species combined was 0.01% (95% confidence limits 0.004-0.02%). This CS protein rate and the mean number of bites received by the collectors indicated a sporozoite inoculation rate of about 10.5 infective bites per person per year. From this value and the number of human malaria cases reported it was estimated that only 0.32% of bites by CS-positive mosquitoes led to a malaria infection. The CS protein rate is so low that this parameter would not be a practical indicator of the efficacy of control campaigns in this area. C1 MINIST SANIDAD & ASISTENCIA SOCIAL, ESCUELA MALARIOL & SANEAMIENTO AMBIENTAL, DIV INVEST, MARACAY 2101A, VENEZUELA. WALTER REED ARMY INST RES, DEPT ENTOMOL, DIV COMMUNICABLE DIS & IMMUNOL, WASHINGTON, DC 20307 USA. UNIV LONDON LONDON SCH HYG & TROP MED, DEPT MED PARASITOL, KEPPEL ST, LONDON WC1E 7HT, ENGLAND. NR 25 TC 38 Z9 40 U1 1 U2 3 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0001-706X EI 1873-6254 J9 ACTA TROP JI Acta Trop. PD DEC PY 1992 VL 52 IS 2-3 BP 167 EP 174 DI 10.1016/0001-706X(92)90033-T PG 8 WC Parasitology; Tropical Medicine SC Parasitology; Tropical Medicine GA KF508 UT WOS:A1992KF50800010 PM 1363181 ER PT J AU DRABICK, JJ WILLIAMS, WJ TANG, DB SUN, W CHUNG, RC AF DRABICK, JJ WILLIAMS, WJ TANG, DB SUN, W CHUNG, RC TI CD4 LYMPHOCYTE DECLINE AND SURVIVAL IN HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Article ID AIDS-RELATED COMPLEX; SAN-FRANCISCO; CONTROLLED TRIAL; NATURAL-HISTORY; COUNTS; HIV; PROGRESSION; ZIDOVUDINE; RISK; ANTIBODIES AB The loss of the CD4 lymphocyte is the central pathophysiologic event in the progression of human immunodeficiency virus (HIV) infection. This retrospective study, based on review of data from deceased HIV patients followed in a single HIV clinic, was conducted to determine if the rate of CD4 lymphocyte decline was predictive of survival. Forty of 172 patients met defined criteria for inclusion in this study. For each patient, CD4-cell counts showed approximate exponential decline over time. A Cox regression analysis was used to assess the association of CD4 cell decline (half-life), race, age, gender, initial CD4-cell count, and treatment (anti-Pneumocystis carinii pneumonia prophylaxis and/or zidovudine vs. no therapy) on total survival (from initial CD4 cell count) and on remaining survival time after reaching a CD4 cell count of 100 (estimated). For all patients, the rate of CD4 cell decline was predictive of total survival (p = .009) but not for survival after reaching a count of 100 (p = .6). For patients who had never received therapy (6 patients), however, the CD4 half-life remained associated with survival time from 100 CD4 cells (p < .05) as opposed to the treated patients. Therapy was the single variable most predictive of both survival endpoints, resulting in an increase in median total survival of 27.2 mo (p < .00001) and of 15.4 mo from a CD4 cell count of 100 (p < .00004). Nonwhites had a slight survival disadvantage compared to whites (p = .08 overall; p = .02 from CD4 cell count of 100). It was concluded that in the natural history of HIV infection, the rate of CD4 cell decline is predictive of total survival. Current therapy can alter the natural history by prolonging life and appears to negate the predictive value of CD4 cell decline on survival from 100 CD4 cells to death. C1 WALTER REED ARMY INST RES,INFECT DIS SERV,WASHINGTON,DC 20307. WALTER REED ARMY INST RES,DEPT BIOMETR,WASHINGTON,DC 20307. RP DRABICK, JJ (reprint author), WALTER REED ARMY INST RES,DEPT BACTERIAL DIS,WASHINGTON,DC 20307, USA. NR 33 TC 10 Z9 10 U1 0 U2 0 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PD DEC PY 1992 VL 8 IS 12 BP 2039 EP 2047 DI 10.1089/aid.1992.8.2039 PG 9 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA KF475 UT WOS:A1992KF47500012 PM 1362886 ER PT J AU WESTON, LT HULL, RW LAIRD, JR CHIN, Y WORTHAM, DC AF WESTON, LT HULL, RW LAIRD, JR CHIN, Y WORTHAM, DC TI A PROTOTYPE CORONARY ELECTRODE CATHETER FOR INTRACORONARY ELECTROGRAM RECORDING SO AMERICAN JOURNAL OF CARDIOLOGY LA English DT Note RP WESTON, LT (reprint author), WALTER REED ARMY MED CTR,CARDIOL SERV,WASHINGTON,DC 20307, USA. NR 4 TC 0 Z9 0 U1 0 U2 0 PU EXCERPTA MEDICA INC PI NEW YORK PA 245 WEST 17TH STREET, NEW YORK, NY 10011 SN 0002-9149 J9 AM J CARDIOL JI Am. J. Cardiol. PD DEC 1 PY 1992 VL 70 IS 18 BP 1492 EP 1493 DI 10.1016/0002-9149(92)90307-K PG 2 WC Cardiac & Cardiovascular Systems SC Cardiovascular System & Cardiology GA KA272 UT WOS:A1992KA27200024 PM 1442626 ER PT J AU VUKELJA, SJ BAKER, WJ JEFFREYS, P REEB, BA PICK, T AF VUKELJA, SJ BAKER, WJ JEFFREYS, P REEB, BA PICK, T TI NONBACTERIAL THROMBOTIC ENDOCARDITIS CLINICALLY MIMICKING VENOOCCLUSIVE DISEASE OF THE LIVER COMPLICATING AUTOLOGOUS BONE-MARROW TRANSPLANTATION SO AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS LA English DT Article DE NONBACTERIAL THROMBOTIC ENDOCARDITIS; AUTOLOGOUS BONE MARROW TRANSPLANTATION; VENOOCCLUSIVE DISEASE ID VENOCCLUSIVE DISEASE AB Nonbacterial thrombotic endocarditis is an uncommon, but well-described, complication of bone marrow transplantation. We describe a case of nonbacterial thrombotic endocarditis following autologous bone marrow transplantation that was marked by weight gain, hepatomegaly, ascites, and extreme hyperbilirubinemia leading to a clinical diagnosis of hepatic veno-occlusive disease. Autopsy revealed nonbacterial thrombotic endocarditis of the tricuspid and pulmonic valves, and passive congestion of the liver, but there was no evidence of veno-occlusive disease. We discuss the pathophysiology and clinical features of nonbacterial thrombotic endocarditis and review its occurrence in association with bone marrow transplantation. Nonbacterial thrombotic endocarditis is often difficult to detect clinically and should be a diagnostic consideration in patients who develop systemic emboli or congestive heart failure after bone marrow transplantation. C1 BROOKE ARMY MED CTR,DEPT PATHOL,FT SAM HOUSTON,TX 78234. BROOKE ARMY MED CTR,DEPT CLIN INVEST,FT SAM HOUSTON,TX 78234. BROOKE ARMY MED CTR,DEPT PEDIAT,FT SAM HOUSTON,TX 78234. RP VUKELJA, SJ (reprint author), BROOKE ARMY MED CTR,DEPT MED,HEMATOL ONCOL SERV,USA,MED CORPS,FT SAM HOUSTON,TX 78234, USA. NR 10 TC 11 Z9 11 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0277-3732 J9 AM J CLIN ONCOL-CANC JI Am. J. Clin. Oncol.-Cancer Clin. Trials PD DEC PY 1992 VL 15 IS 6 BP 500 EP 502 DI 10.1097/00000421-199212000-00008 PG 3 WC Oncology SC Oncology GA KB216 UT WOS:A1992KB21600010 PM 1449113 ER PT J AU SHAFFER, RT LAHATTE, LJ KELLY, JW KADAKIA, S CARROUGHER, JG KEATE, RF STARNES, EC AF SHAFFER, RT LAHATTE, LJ KELLY, JW KADAKIA, S CARROUGHER, JG KEATE, RF STARNES, EC TI GASTRIC-ACID SECRETION IN HIV-1 INFECTION SO AMERICAN JOURNAL OF GASTROENTEROLOGY LA English DT Article ID ACQUIRED IMMUNODEFICIENCY SYNDROME; SYNDROME AIDS; GASTROINTESTINAL MANIFESTATIONS; CAMPYLOBACTER-PYLORIDIS; EPIDEMIC GASTRITIS; KETOCONAZOLE; HYPOCHLORHYDRIA; MALABSORPTION; ENTEROPATHY; PH AB It has been suggested that AIDS patients may have reduced gastric acid output. This is of concern because gastric acid may be required for absorption of oral antifungal agents that are important in AIDS management. The cause as well as the progression of reduced gastric acid output in AIDS patients is unclear. This study investigated gastric acid output in relation to the stage of non-AIDS HIV-1-infected patients. No statistical difference was found between nine control and 26 male HIV-infected subjects in basal acid output, maximal acid output, peak acid output, or fasting serum gastrin, regardless of stage. Likewise, no relationship between stage of HIV infection and gastric acid output was determined. We conclude that there is no impairment in basal and maximally stimulated gastric acid secretion in non-AIDS HIV-1-infected males. In addition, the clinical stage of non-AIDS HIV-1 infection has no effect on gastric acid secretion. C1 BROOKE ARMY MED CTR,DEPT MED,GASTROENTEROL SERV,SAN ANTONIO,TX. BROOKE ARMY MED CTR,DEPT MED,INFECT DIS SERV,SAN ANTONIO,TX. NR 31 TC 28 Z9 28 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0002-9270 J9 AM J GASTROENTEROL JI Am. J. Gastroenterol. PD DEC PY 1992 VL 87 IS 12 BP 1777 EP 1780 PG 4 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA KB241 UT WOS:A1992KB24100017 PM 1449140 ER PT J AU WISWELL, TE AF WISWELL, TE TI MECONIUM ASPIRATION SYNDROME MADE MURKIER SO AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY LA English DT Letter ID INFANTS; SUCTION RP WISWELL, TE (reprint author), WALTER REED ARMY MED CTR,DEPT PEDIAT,NEONATAL SERV,WASHINGTON,DC 20307, USA. NR 13 TC 8 Z9 8 U1 0 U2 0 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0002-9378 J9 AM J OBSTET GYNECOL JI Am. J. Obstet. Gynecol. PD DEC PY 1992 VL 167 IS 6 BP 1914 EP 1916 PG 3 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA KD429 UT WOS:A1992KD42900080 PM 1471721 ER PT J AU GORDON, SW TAMMARIELLO, RF LINTHICUM, KJ DOHM, DJ DIGOUTTE, JP CALVOWILSON, MA AF GORDON, SW TAMMARIELLO, RF LINTHICUM, KJ DOHM, DJ DIGOUTTE, JP CALVOWILSON, MA TI ARBOVIRUS ISOLATIONS FROM MOSQUITOS COLLECTED DURING 1988 IN THE SENEGAL RIVER BASIN SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID RIFT-VALLEY FEVER; EPIDEMIC; MAURITANIA AB During August and September 1988, we collected adult mosquitoes from 14 locations in the Senegal River basin to search for evidence of Rift Valley fever (RVF) viral activity one year after the 1987 outbreak, which occurred along the Senegal-Mauritania border. More than 62,000 specimens representing 18 species in seven genera were collected with carbon dioxide-baited, solid-state Army miniature light traps and sheep-baited traps. Twenty virus isolations from Culex, Aedes, and Anopheles mosquitoes were recovered from six locations: Fanaye Diery (11), Bode (four), Matam (two), Diongui (one), Ndialene (one), and Ngoui (one). Species yielding viral isolates were Anopheles pharoensis (eight), Culex tritaeniorhynchus (three), Cx. univitattus gr. (three), Cx. antennatus (two), Cx. poicillipes (two), Ae. hirsutus (one), and An. gambiae (one). Viruses were identified by complement fixation, and virus and plaque-reduction neutralization testing as Ngari (Bunyavirus, Bunyaviridae) (n = 15), Babanki (Alphavirus, Togaviridae) (n = 3), Bagaza (Flavivirus, Flaviviridae) (n = 1), and Bangui (Bunyavirus-like) (n = 1). No evidence of any RVF viral activity in the Senegal River Basin was detected in the mosquitoes tested. C1 INST PASTEUR,DAKAR,SENEGAMBIA. RP GORDON, SW (reprint author), USA,MED RES INST INFECT DIS,DIV VIROL,DEPT ARBOVIRAL ENTOMOL,FT DETRICK,FREDERICK,MD 21702, USA. RI Gordon, Scott/B-8875-2011 NR 23 TC 23 Z9 23 U1 3 U2 6 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD DEC PY 1992 VL 47 IS 6 BP 742 EP 748 PG 7 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA KF920 UT WOS:A1992KF92000004 PM 1361722 ER PT J AU MILLS, JN ELLIS, BA MCKEE, KT CALDERON, GE MAIZTEGUI, JI NELSON, GO KSIAZEK, TG PETERS, CJ CHILDS, JE AF MILLS, JN ELLIS, BA MCKEE, KT CALDERON, GE MAIZTEGUI, JI NELSON, GO KSIAZEK, TG PETERS, CJ CHILDS, JE TI A LONGITUDINAL-STUDY OF JUNIN VIRUS ACTIVITY IN THE RODENT RESERVOIR OF ARGENTINE HEMORRHAGIC-FEVER SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID CALOMYS-MUSCULINUS; NATURAL RESERVOIR; ENDEMIC AREA; TRANSMISSION; INFECTION; HABITAT AB We monitored Junin virus (JV) activity in rodent populations for 30 months at seven mark-recapture grids located in agricultural fields and adjacent roadsides and fence lines in endemic and nonendemic areas of Argentine hemorrhagic fever. Blood and oral swabs taken from rodents captured at five-week intervals were analyzed by enzyme-linked immunosorbent assay for JV antigen (Ag). Calomys laucha and C. musculinus were the most frequently captured rodents, making up 47% and 22% of captures, respectively. Of 41 Ag-positive captures, 37 were C. musculinus and four were C. laucha; 34 were from two trapping grids in the same locality. Antigen-positive Calomys were more frequently male (76%), and were found significantly more frequently among the oldest animals and the largest body mass classes. These patterns, combined with the greater mobility and higher frequencies of wounds among males than females, implicated horizontal transmission as the primary route of JV transmission between rodents. Seasonal maximum levels in JV prevalence (up to 25% of captured Ag-positive C musculinus) occurred during periods of maximal population densities of Calomys. Spatial distribution of Ag-positive rodents reflected habitat preferences; most Ag-positive C musculinus were captured from border habitats (roadsides and fence lines), and all Ag-positive C. laucha were captured in crop fields. These distinct, but previously undocumented, habitat preferences suggest that the disease in humans may be related to exposures to the primary reservoir species, C musculinus, in border habitats rather than in crop fields. C1 JOHNS HOPKINS UNIV,SCH HYG & PUBL HLTH,DEPT IMMUNOL & INFECT DIS,BALTIMORE,MD 21218. INST NACL ESTUDIOS SOBRE VIROSIS HEMORRAG,PERGAMINO,ARGENTINA. RP MILLS, JN (reprint author), USA,MED RES INST INFECT DIS,DIV VIROL,FT DETRICK,FREDERICK,MD 21702, USA. RI Childs, James/B-4002-2012 NR 24 TC 89 Z9 93 U1 0 U2 6 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD DEC PY 1992 VL 47 IS 6 BP 749 EP 763 PG 15 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA KF920 UT WOS:A1992KF92000005 PM 1335214 ER PT J AU BURKOT, TR WIRTZ, RA PARU, R GARNER, P ALPERS, MP AF BURKOT, TR WIRTZ, RA PARU, R GARNER, P ALPERS, MP TI THE POPULATION-DYNAMICS IN MOSQUITOS AND HUMANS OF 2 PLASMODIUM-VIVAX POLYMORPHS DISTINGUISHED BY DIFFERENT CIRCUMSPOROZOITE PROTEIN REPEAT REGIONS SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID PAPUA-NEW-GUINEA; MONOCLONAL-ANTIBODIES; MALARIA TRANSMISSION; WUCHERERIA-BANCROFTI; ELISA DEVELOPMENT; FALCIPARUM; PREVALENCE; SPOROZOITES; AREA; ANOPHELINES AB The population dynamics of two Plasmodium vivax polymorphs were studied over a two-year period in a village in a hyperendemic area of Papua New Guinea in both the mosquito and human populations. Strains of P. vivax were distinguished by different circumsporozoite (CS) protein repeats, the VK210 (classic) and the VK247 (variant) polymorphs. In 1986, 34% of P. vivax CS protein-positive mosquitoes were of the VK247 type. Although the proportion of P. vivax sporozoite antigen-positive mosquitoes compared with all sporozoite-positive mosquitoes did not change from 1986 to 1987, the proportion of P. vivax-positive mosquitoes of the VK247 polymorph decreased significantly from 34% to 11% (5 of 45) in 1987. In 1986, 61% (47 of 77) of humans tested had IgGs that recognized the VK247 CS repeat, while only 26% (22 of 84) had IgGs that recognized the VK210 CS repeat. The observed fluctuation in the proportion of the two P. vivax CS protein polymorphs recorded in the mosquito population from 1986 to 1987 is consistent with a hypothesis of selection by humoral immune pressure on the VK247 strain. C1 QUEENSLAND INST MED RES,BRISBANE,QLD,AUSTRALIA. WALTER REED ARMY INST RES,DEPT ENTOMOL,DIV COMMUNICABLE DIS & IMMUNOL,WASHINGTON,DC 20307. PAPUA NEW GUINEA INST MED RES,MADANG,PAPUA N GUINEA. UNIV LONDON LONDON SCH HYG & TROP MED,LONDON WC1E 7HT,ENGLAND. PAPUA NEW GUINEA INST MED RES,GOROKA,PAPUA N GUINEA. RP BURKOT, TR (reprint author), CTR DIS CONTROL,DIV VECTOR BORNE INFECT DIS,POB 2087,FT COLLINS,CO 80522, USA. RI Burkot, Thomas/C-6838-2013 NR 24 TC 19 Z9 19 U1 0 U2 2 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD DEC PY 1992 VL 47 IS 6 BP 778 EP 786 PG 9 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA KF920 UT WOS:A1992KF92000008 PM 1471735 ER PT J AU LOOAREESUWAN, S KYLE, DE VIRAVAN, C VANIJANONTA, S WILAIRATANA, P CHAROENLARP, P CANFIELD, CJ WEBSTER, HK AF LOOAREESUWAN, S KYLE, DE VIRAVAN, C VANIJANONTA, S WILAIRATANA, P CHAROENLARP, P CANFIELD, CJ WEBSTER, HK TI TREATMENT OF PATIENTS WITH RECRUDESCENT FALCIPARUM-MALARIA WITH A SEQUENTIAL COMBINATION OF ARTESUNATE AND MEFLOQUINE SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID THAI-BURMESE BORDER; PLASMODIUM-FALCIPARUM; SULFADOXINE-PYRIMETHAMINE; HALOFANTRINE; ARTEMISININ; QINGHAOSU AB A sequential combination of artesunate followed by mefloquine was evaluated prospectively in 24 patients with acute recrudescent falciparum malaria. The sequential combination was used to minimize possible side effects and to take advantage of the ability of artesunate to rapidly clear parasitemia and the prolonged effect of mefloquine to clear residual parasites. All patients had experienced one or more treatment failures with one or more courses of the following drugs (administered alone or in combination): quinine, tetracycline, mefloquine, artesunate, and sulfadoxine/pyrimethamine. Sequential treatment with artesunate (600 mg over five days) followed by mefloquine (750 mg and 500 mg six hours apart) cured all 24 patients. Each patient was followed for 28 days and 10 were observed for at least 35 days without clinical or parasitologic evidence of recrudescence. Fever and parasite clearance times after treatment with the sequential combination were 32.8 +/- 19.3 hr (mean +/- SD) and 40.0 +/- 16.2 hr, respectively. Susceptibility testing of selected parasite isolates indicated that all of the isolates tested were resistant to one or more antimalarial drugs. These results suggest that sequential treatment with artesunate followed by mefloquine is effective and well-tolerated in patients with recrudescent falciparum malaria. C1 USAMC,ARMED FORCES RES INST MED SCI,DEPT IMMUNOL,BANGKOK,THAILAND. PHARMACEUT SYST INC,GAITHERSBURG,MD. RP LOOAREESUWAN, S (reprint author), MAHIDOL UNIV,BANGKOK HOSP TROP DIS,FAC TROP MED,420-6 RAJAVITHI RD,BANGKOK 10400,THAILAND. NR 20 TC 51 Z9 51 U1 0 U2 1 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD DEC PY 1992 VL 47 IS 6 BP 794 EP 799 PG 6 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA KF920 UT WOS:A1992KF92000010 PM 1471736 ER PT J AU JONES, TR YUAN, LF MARWOTO, HA GORDON, DM WIRTZ, RA HOFFMAN, SL AF JONES, TR YUAN, LF MARWOTO, HA GORDON, DM WIRTZ, RA HOFFMAN, SL TI LOW IMMUNOGENICITY OF A PLASMODIUM-VIVAX CIRCUMSPOROZOITE PROTEIN EPITOPE BOUND BY A PROTECTIVE MONOCLONAL-ANTIBODY SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID IMMUNODOMINANT EPITOPE; SPOROZOITE VACCINE; MALARIA VACCINE; FALCIPARUM; SEQUENCE; SAFETY AB The repeat region of the Plasmodium vivax circumsporozoite (CS) protein contains 20 copies of the nine-amino acid sequence DRA A/D GQPAG. A monoclonal antibody that passively protects monkeys against sporozoite challenge recognizes a four-amino acid linear sequence AGDR included within this nonamer, but when monkeys were immunized with a vaccine, NS1(81)V20, which contains 20 copies of the nonamer, they failed to produce antibodies to AGDR. To determine if natural exposure to sporozoites induces antibodies to AGDR, we tested sera from 176 individuals from a malaria-endemic area in Flores, Indonesia. Seventy-one percent of the adults had antibodies to the P. vivax repeat region; only 18% had detectable antibodies to AGDR. None of the subjects had antibodies to the P. vivax variant repeat ANGAGNQPG. We next tested sera from six human volunteers immunized with NS1(81)V20 and found that the vaccine, despite inducing antibodies against the nonamer, as it did in the monkeys, did not induce antibodies against AGDR. To further test our ability to raise anti-AGDR antibodies using synthetic peptides, we immunized Aotus monkeys and BALB/c mice with AGDR. Sera from the mice reacted strongly with both AGDR and a recombinant protein containing the 20 copies of the nonamer. Sera from the monkeys reacted only minimally with a protein (VIVAX-1) that contains monomeric AGDR within its sequence. Sera from the mice also bound air-dried P. vivax sporozoites, while sera from the monkeys did not. These data indicate that natural exposure induces very low levels of antibodies to the CS protein epitope AGDR, and that polyclonal antibodies that recognize native CS protein can be induced experimentally with a synthetic AGDR peptide. C1 NATL INST HLTH RES & DEV,JAKARTA,INDONESIA. WALTER REED ARMY INST RES,WASHINGTON,DC 20307. RP JONES, TR (reprint author), USN,MED RES INST,12300 WASHINGTON AVE,ROCKVILLE,MD 20852, USA. NR 15 TC 11 Z9 11 U1 0 U2 1 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD DEC PY 1992 VL 47 IS 6 BP 837 EP 843 PG 7 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA KF920 UT WOS:A1992KF92000017 PM 1471743 ER PT J AU MEBRAHTU, YB LAWYER, PG PAMBA, H KOECH, D PERKINS, PV ROBERTS, CR WERE, JB HENDRICKS, LD AF MEBRAHTU, YB LAWYER, PG PAMBA, H KOECH, D PERKINS, PV ROBERTS, CR WERE, JB HENDRICKS, LD TI BIOCHEMICAL-CHARACTERIZATION AND ZYMODEME CLASSIFICATION OF LEISHMANIA ISOLATES FROM PATIENTS, VECTORS, AND RESERVOIR HOSTS IN KENYA SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID L-TROPICA ZYMODEMES; CUTANEOUS LEISHMANIASIS; OLD-WORLD; VISCERAL LEISHMANIASIS; SEROLOGICAL TAXONOMY; PHLEBOTOMUS-DUBOSCQI; SUBGENUS TRYPANOZOON; PARASITIC PROTOZOA; BARINGO DISTRICT; IDENTIFICATION AB A total of 407 Leishmania and other Leishmania-like isolates obtained from patients, other vertebrates, sand fly vectors, and other arthropods from Kenya and other countries were characterized and compared with several World Health Organization and other well-characterized reference strains of Leishmania, Trypanosoma, Crithidia, Herpetomonas, and Leptomonas by cellulose acetate electrophoresis (CAE), using 20 enzyme systems. Analysis of the isoenzyme banding patterns (IBP) of the isolates generated isoenzyme profiles that were resolved as zymodemes and tabulated. Isolates that produced similar isoenzyme profiles in all 20 enzyme systems were placed into a particular Leishmania isoenzyme taxon, with the zymodeme designated numerically as Z(n). A total of 66 zymodemes were recorded for the 407 isolates studied. To obviate the need to draw all 66 representative IBP for each of the 20 enzyme systems, the 66 zymodemes (Z1-Z66) were again placed into similarity groups represented by pattern number or P(n). This resulted in 23-50 IBP (P(n)) per enzyme system. The highest number of IBP scored was for malate dehydrogenase (MDH) (P1-50) and the lowest score was for glucose-6-phosphate isomerase (GPI) (P1-23). From these different isoenzyme profiles or zymodemes, IBP of 14 (MDH, GPI, nucleoside hydrolase, phosphoglucomutase, malic enzyme, isocitrate dehydrogenase, glucose-6-phosphate dehydrogenase, mannose-6-phosphate isomerase, 6-phosphogluconate dehydrogenase, glutamate oxaloacetate transferase/aspartate aminotransferase, glutathione reductase, superoxide dismutase, fumarase, and glyceraldehyde-3-phosphate dehydrogenase) of the 20 enzyme system s were selected for computer-calculated numerical taxonomy. Consistent individual isoenzyme bands with similar relative mobilities of the 14 enzyme systems were scored into groups (allelomorphs, allozymes, or electromorphs) and used in cluster analysis. For each pattern in every profile, the presence of a consistent band was entered as 1 and its absence as 0. A total of 419 allozyme characters (variables) were scored for the 14 enzyme systems. Lastly, all different zymodemes sharing a particular IBP (P(n)) within an enzyme system were counted and the total number was shown as a zymodeme frequency (Z(f)). Final analysis of the CAE isoenzyme profiles and cluster-dendrograms resulted in the identification of several potentially new species and subspecies of Leishmania and other Leishmania-like isolates from patients, sand flies, and animal reservoir hosts collected from Kenya and other locations in Africa. Zymodeme analysis of the Kenyan visceral and cutaneous leishmaniasis isolates resulted in the identification of 11 subpopulations of the L. donovani species complex and six subpopulations of the L. tropica species complex endemic to different geographic areas of Kenya. C1 WALTER REED ARMY INST RES,WASHINGTON,DC 20307. RP MEBRAHTU, YB (reprint author), UNIV NAIROBI,FAC MED,USA,MED RES UNIT,KENYA MED RES INST,POB 30137,NAIROBI,KENYA. NR 80 TC 25 Z9 25 U1 1 U2 2 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD DEC PY 1992 VL 47 IS 6 BP 852 EP 892 PG 41 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA KF920 UT WOS:A1992KF92000019 PM 1471744 ER PT J AU CRAIG, TJ HERSHEY, J ENGLER, RJM DAVIS, W CARPENTER, GB SALATA, K AF CRAIG, TJ HERSHEY, J ENGLER, RJM DAVIS, W CARPENTER, GB SALATA, K TI BIRD ANTIGEN PERSISTENCE IN THE HOME-ENVIRONMENT AFTER REMOVAL OF THE BIRD SO ANNALS OF ALLERGY LA English DT Article ID PIGEON-BREEDERS; FANCIERS AB Hypersensitivity pneumonitis (HP) secondary to bird exposure is treated with glucocorticosteroids and avoidance. Despite therapy, symptoms may persist for a prolonged time. Just as cat antigen, Fel d 1, may persist for greater than 20 weeks after cat removal, there may be persistent bird antigen to explain prolonged symptoms in bird HP. It was the intent of this study to determine household distribution and persistence of bird antigen after removal of the bird from the patient's home. The homes of patients with birds were followed serially after bird removal with multiple samples collected using a hand-held vacuum cleaner. Bird antigen levels were determined by an inhibition enzyme-linked immunoassay. In five homes the antigen declined gradually despite extensive environmental control measures, with high levels still detectable at 18 months in one home. This data suggests that high levels of bird antigen can be detected for prolonged periods of time after bird removal and environmental cleanup. The antigen may account for the persistence of disease in some patients with HP. In severe HP, the preferred therapy may be temporary relocation of the patient away from the room in which the bird was housed, in addition to corticosteroids, until the patient's environment is demonstrated to be relatively bird antigen-free. C1 WALTER REED ARMY MED CTR,ALLERGY IMMUNOL SERV,WASHINGTON,DC 20307. NR 5 TC 24 Z9 26 U1 1 U2 1 PU AMER COLL ALLERGY ASTHMA IMMUNOLOGY PI ARLINGTON HTS PA 85 WEST ALGONQUIN RD SUITE 550, ARLINGTON HTS, IL 60005 SN 0003-4738 J9 ANN ALLERGY JI Ann. Allergy PD DEC PY 1992 VL 69 IS 6 BP 510 EP 512 PG 3 WC Allergy SC Allergy GA KD426 UT WOS:A1992KD42600009 PM 1471783 ER PT J AU KROENKE, K LUCAS, CA ROSENBERG, ML SCHEROKMAN, B HERBERS, JE WEHRLE, PA BOGGI, JO AF KROENKE, K LUCAS, CA ROSENBERG, ML SCHEROKMAN, B HERBERS, JE WEHRLE, PA BOGGI, JO TI CAUSES OF PERSISTENT DIZZINESS - A PROSPECTIVE-STUDY OF 100 PATIENTS IN AMBULATORY CARE SO ANNALS OF INTERNAL MEDICINE LA English DT Article DE DIZZINESS; AMBULATORY CARE; VESTIBULAR DISEASES; VERTIGO; PSYCHIATRIC STATUS RATING SCALES ID DIAGNOSTIC INTERVIEW SCHEDULE; DIZZY PATIENT; GENERAL-POPULATION; MEDICAL OUTCOMES; CLINICAL METHODS; RELIABILITY; SYMPTOMS; VALIDITY; THERAPY; HYPERVENTILATION AB Objective: To determine the causes of persistent dizziness in outpatients. Design: Consecutive adult outpatients presenting with a chief complaint of dizziness. Setting: Four clinics (internal medicine, walk-in, emergency room, and neurology) in a teaching hospital. Patients: Of 185 patients presenting during the 10-month study period, 51 (28%) had minimal or no dizziness at 2-week follow-up. Of the remaining 134 patients, 100 completed the study protocol (mean age, 62 years; range, 20 to 85 years). Measurements: Evaluation included a detailed study questionnaire, standardized physical examination, vestibular testing by a neuro-ophthalmologist, laboratory tests, audiometry, and a structured psychiatric interview. Data were abstracted onto a standard form and reviewed by three raters. Raters independently assigned diagnoses using explicit criteria, with the final cause determined by consensus. Results: Primary causes of dizziness included vestibular disorders (54 patients), psychiatric disorders (16 patients), presyncope (6 patients), dysequilibrium (2 patients), and hyperventilation (1 patient); dizziness was multicausal in 13 patients and of unknown cause in 8 patients. Many of those with a single primary cause, however, had at least one other condition contributing to their dizziness; only 52% of patients had a single "pure" cause. Thirty patients had a potentially treatable primary cause, the most common being benign positional vertigo (BPV) (16%) and psychiatric disorders (6%). Central vestibulopathies detected in 10 patients were presumably vascular or idiopathic in origin. No brain tumors or cardiac arrhythmias were found. Conclusions: Vestibular disease and psychiatric disorders are the most common causes of persistent dizziness in outpatients. In about 50% of patients with dizziness, more than one factor causes or aggravates symptoms. Life-threatening causes were rare, even in our elderly population. C1 UNIFORMED SERV UNIV HLTH SCI,DEPT NEUROL,BETHESDA,MD 20814. WALTER REED ARMY MED CTR,WASHINGTON,DC 20307. RP KROENKE, K (reprint author), UNIFORMED SERV UNIV HLTH SCI,DEPT MED,4301 JONES BRIDGE RD,BETHESDA,MD 20814, USA. NR 36 TC 140 Z9 144 U1 2 U2 8 PU AMER COLL PHYSICIANS PI PHILADELPHIA PA INDEPENDENCE MALL WEST 6TH AND RACE ST, PHILADELPHIA, PA 19106-1572 SN 0003-4819 J9 ANN INTERN MED JI Ann. Intern. Med. PD DEC 1 PY 1992 VL 117 IS 11 BP 898 EP 904 PG 7 WC Medicine, General & Internal SC General & Internal Medicine GA JZ276 UT WOS:A1992JZ27600004 PM 1443950 ER PT J AU OLDER, SA FINBLOOM, DS PEZESHKPOUR, GH AF OLDER, SA FINBLOOM, DS PEZESHKPOUR, GH TI COLCHICINE MYONEUROPATHY AND RENAL DYSFUNCTION SO ANNALS OF THE RHEUMATIC DISEASES LA English DT Letter ID MICROTUBULES; NEUROPATHY; TOXICITY; MYOPATHY C1 US FDA,DIV CYTOKINE BIOL,BETHESDA,MD 20014. ARMED FORCES INST PATHOL,NEUROMUSCULAR SECT,WASHINGTON,DC 20306. RP OLDER, SA (reprint author), BROOKE ARMY MED CTR,DEPT MED,RHEUMATOL SERV,FT SAM HOUSTON,TX 78234, USA. NR 10 TC 4 Z9 4 U1 0 U2 0 PU BRITISH MED JOURNAL PUBL GROUP PI LONDON PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON, ENGLAND WC1H 9JR SN 0003-4967 J9 ANN RHEUM DIS JI Ann. Rheum. Dis. PD DEC PY 1992 VL 51 IS 12 BP 1343 EP 1344 DI 10.1136/ard.51.12.1343 PG 2 WC Rheumatology SC Rheumatology GA KC226 UT WOS:A1992KC22600017 PM 1485821 ER PT J AU COHEN, AJ BANKS, A CAMBIER, P EDWARDS, FH AF COHEN, AJ BANKS, A CAMBIER, P EDWARDS, FH TI POST-ATHERECTOMY CORONARY-ARTERY ANEURYSM SO ANNALS OF THORACIC SURGERY LA English DT Article AB A 52-year-old man underwent an uneventful directional atherectomy of the left anterior descending coronary artery. Four months after the procedure unstable angina developed and on angiogram an aneurysm of the left anterior descending coronary artery was noted. The patient underwent bypass of the left anterior descending coronary artery. An attempt to exclude the aneurysm resulted in hemodynamic compromise and was discontinued. Follow-up angiogram 2 months after operation showed the aneurysm to be smaller. The patient is doing well 6 months after operation. C1 WALTER REED ARMY MED CTR,DEPT SURG,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,DEPT CARDIOVASC DIS,WASHINGTON,DC 20307. UNIFORMED SERV UNIV HLTH SCI,DEPT SURG,BETHESDA,MD 20814. NR 7 TC 9 Z9 9 U1 0 U2 0 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0003-4975 J9 ANN THORAC SURG JI Ann. Thorac. Surg. PD DEC PY 1992 VL 54 IS 6 BP 1216 EP 1218 PG 3 WC Cardiac & Cardiovascular Systems; Respiratory System; Surgery SC Cardiovascular System & Cardiology; Respiratory System; Surgery GA KA693 UT WOS:A1992KA69300037 PM 1449316 ER PT J AU GERENA, L BASS, GT KYLE, DE ODUOLA, AMJ MILHOUS, WK MARTIN, RK AF GERENA, L BASS, GT KYLE, DE ODUOLA, AMJ MILHOUS, WK MARTIN, RK TI FLUOXETINE HYDROCHLORIDE ENHANCES INVITRO SUSCEPTIBILITY TO CHLOROQUINE IN RESISTANT PLASMODIUM-FALCIPARUM SO ANTIMICROBIAL AGENTS AND CHEMOTHERAPY LA English DT Article ID MULTIDRUG RESISTANCE; POTENTIATING ACTION; MEMBRANE-VESICLES; REVERSAL; MALARIA; CELLS; AMPLIFICATION; TETRANDRINE; GENE AB The emergence of chloroquine resistance in Plasmodium falciparum has necessitated the development of alternate strategies for chemotherapy and chemoprophylaxis. One approach has been the identification of drugs that do not possess any intrinsic antimalarial activity when used alone but that potentiate the effect of currently available antimalarial drugs, such as chloroquine. We identified fluoxetine hydrochloride (Prozac), a commonly prescribed antidepressant, as another resistance modulator for drug-resistant P. falciparum. Studies with chloroquine-resistant clones and isolates from various geographical locations confirmed our initial observations with a chloroquine-resistant P. falciparum clone, W2. Fluoxetine concentrations of 500 nM were found to effectively modulate chloroquine resistance by 66% in clone W2. In comparison, verapamil at similar concentrations was observed to modulate chloroquine resistance in clone W2 by 61%. Neither fluoxetine nor verapamil was observed to possess any innate antimalarial activity. These data augment the current description of the chloroquine resistance phenotype and may provide additional insights into lead-directed synthesis of new antimalarial drugs. C1 WALTER REED ARMY INST RES,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307. UNIV IBADAN,MALARIA RES LAB,IBADAN,NIGERIA. NR 22 TC 32 Z9 33 U1 0 U2 4 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0066-4804 J9 ANTIMICROB AGENTS CH JI Antimicrob. Agents Chemother. PD DEC PY 1992 VL 36 IS 12 BP 2761 EP 2765 PG 5 WC Microbiology; Pharmacology & Pharmacy SC Microbiology; Pharmacology & Pharmacy GA KA934 UT WOS:A1992KA93400032 PM 1482144 ER PT J AU STANLEY, AE LUDWICK, LM WHITE, D ANDREWS, DE GODBEY, SE AF STANLEY, AE LUDWICK, LM WHITE, D ANDREWS, DE GODBEY, SE TI SULFUR-HEXAFLUORIDE - OPTIMAL USE AS A GAS-PHASE, INFRARED SENSITIZER SO APPLIED SPECTROSCOPY LA English DT Article DE LASER; INFRARED; SULFUR HEXAFLUORIDE; NITRATION ID RAMAN-SPECTRA AB Investigations into the use of sulfur hexafluoride, SF6, as a gas-phase, infrared photochemical sensitizer have revealed several interesting phenomena. The expedient use of SF6 can produce an optimal quantity of nitrated product in the gas-phase, laser-induced nitration of cyclopentane. The optimal utilization of sulfur hexafluoride required critical optimization of both frequency and quantity. The results are described herein. RP STANLEY, AE (reprint author), USA,MISSILE COMMAND,CTR RES DEV & ENGN,WEAPONS SCI DIRECTORATE,REDSTONE ARSENAL,AL 35898, USA. NR 12 TC 3 Z9 3 U1 0 U2 2 PU SOC APPLIED SPECTROSCOPY PI FREDERICK PA PO BOX 1438, FREDERICK, MD 21701 SN 0003-7028 J9 APPL SPECTROSC JI Appl. Spectrosc. PD DEC PY 1992 VL 46 IS 12 BP 1866 EP 1868 DI 10.1366/0003702924123467 PG 3 WC Instruments & Instrumentation; Spectroscopy SC Instruments & Instrumentation; Spectroscopy GA KH218 UT WOS:A1992KH21800019 ER PT J AU KIRKLAND, FR AF KIRKLAND, FR TI GOVERNMENTAL POLICY AND COMBAT EFFECTIVENESS - FRANCE 1920-1940 SO ARMED FORCES & SOCIETY LA English DT Article AB French governmental policy and legislation between the world wars had unintended effects on the moral and efficiency of military officers. The second-order effects were progression of officers' morale from psychological autonomy toward dependency. These effects can be discerned from an analysis of articles in military journals between 1920 and 1940. The third-order effects were on efficiency. They included the officers' growing inability to cooperate across branches, unwillingness to attend to technological developments, and unquestioning acceptance of an obsolete military doctrine - behavior that contributed to their defeat in 1940. The French experience illustrates processes through which unexamined governmental action can degrade the combat effectiveness of an armed force. RP KIRKLAND, FR (reprint author), WALTER REED ARMY MED CTR,DEPT MIL PSYCHIAT,DIV NEUROPSYCHIAT,WASHINGTON,DC 20307, USA. RI Dopko, Rae/J-7437-2015 NR 138 TC 0 Z9 0 U1 0 U2 0 PU TRANSACTION PERIOD CONSORTIUM PI NEW BRUNSWICK PA DEPT 3091 RUTGERS-THE STATE UNIV OF NJ, NEW BRUNSWICK, NJ 08903 SN 0095-327X J9 ARMED FORCES SOC JI Armed Forces Soc. PD WIN PY 1992 VL 18 IS 2 BP 175 EP 191 DI 10.1177/0095327X9201800202 PG 17 WC Political Science; Sociology SC Government & Law; Sociology GA HG163 UT WOS:A1992HG16300002 ER PT J AU KEARL, CE NELSON, A AF KEARL, CE NELSON, A TI THE ARMY DELAYED ENTRY PROGRAM SO ARMED FORCES & SOCIETY LA English DT Article AB The Delayed Entry Program, which allows individuals to delay reporting for active duty up to 12 months after signing enlistment contracts, is a valuable management tool used by the U.S. Army Recruiting Command and other U.S. military recruiting organizations. Attrition from this program increases recruiting costs and reduces training efficiency. DEP attrition is analyzed here using microdata for individuals who signed Army enlistment contracts during fiscal years 1986 and 1987. The findings indicate that the strongest predictors of DEP attrition are related to personal characteristics. Being younger, male, black, a high school graduate, and having dependents reduces the likelihood a recruit will be a DEP loss. Economic factors also influence DEP loss. The results suggest that as the economy becomes stronger, DEP loss is more prevalent. Increasing recruiting incentives result in small, but significant, reductions in the probability of DEP loss. The findings also indicate longer DEP terms increase DEP attrition. C1 USA,RES INST,5001 EISENHOWER AVE,ALEXANDRIA,VA 22333. USN,RECRUITING COMMAND,WASHINGTON,DC 20350. UNIV MARYLAND,COLLEGE PK,MD 20742. NR 11 TC 1 Z9 1 U1 1 U2 1 PU TRANSACTION PERIOD CONSORTIUM PI NEW BRUNSWICK PA DEPT 3091 RUTGERS-THE STATE UNIV OF NJ, NEW BRUNSWICK, NJ 08903 SN 0095-327X J9 ARMED FORCES SOC JI Armed Forces Soc. PD WIN PY 1992 VL 18 IS 2 BP 253 EP 268 DI 10.1177/0095327X9201800206 PG 16 WC Political Science; Sociology SC Government & Law; Sociology GA HG163 UT WOS:A1992HG16300006 ER PT J AU COHEN, DJ CLEM, MF LUTHER, M GENECOV, DG HAMEL, JD BEGIA, BC SANGALLI, M EVANS, K FLORES, J BUNEGIN, M GRAEBER, GM GROVER, FL AF COHEN, DJ CLEM, MF LUTHER, M GENECOV, DG HAMEL, JD BEGIA, BC SANGALLI, M EVANS, K FLORES, J BUNEGIN, M GRAEBER, GM GROVER, FL TI EFFECT OF SYNCHRONOUS AND ASYNCHRONOUS PULSATILE FLOW DURING LEFT, RIGHT, AND BIVENTRICULAR BYPASS SO ARTIFICIAL ORGANS LA English DT Article DE PULSATILE FLOW; VENTRICULAR ASSIST DEVICE; MYOCARDIAL OXYGEN CONSUMPTION; R-WAVE SYNCHRONIZATION; MYOCARDIAL INFARCTION; PIERCE-DONACHY VENTRICULAR ASSIST DEVICE ID LEFT HEART BYPASS; VENTRICULAR ASSIST DEVICE; CARDIOGENIC-SHOCK; PUMP; EXPERIENCE; SURVIVAL AB Ventricular assist devices augment flow from the left atrium to the aorta and/or from the right atrium to the pulmonary artery. Most devices are used in the asynchronous full-to-empty mode (asynchronous) but may also be used in a synchronous counterpulsation mode (synchronous). This study determines the optimal assist modes to reduce myocardial oxygen consumption (MVO2) and metabolism. Twelve pigs were instrumented with carotid artery and Baim coronary sinus catheters for determination of MVO2 and myocardial lactate production (LACT). Six were implanted with a Pierce-Donachy left ventricular assist device (LVAD) and 6 with both right and left ventricular assist devices (BIVAD). Two periods each of control, synchronous, and asynchronous bypass were instituted, the midanterior descending coronary artery (LAD) was ligated, and the sequence was repeated. After each period, MVO2 and LACT were determined and myocardial biopsy specimens were obtained for tissue, lactate, and ATP assay. Following LAD ligation, biopsy specimens were obtained from both the infarct and noninfarct zones of the heart. MVO2 decreased (p < 0.05) in the asynchronous BIVAD mode compared with control. MVO2 was unchanged in synchronous BIVAD or either LVAD mode. Tissue ATP and tissue lactate were unaffected by any mode of bypass. Only BIVAD in the asynchronous mode reduced MVO2. When ventricular assist devices are utilized to aid recovery of the natural heart, two devices should always be inserted to allow biventricular assist. Synchronous counterpulsation offers no advantage. C1 UNIV TEXAS,HLTH SCI CTR,DEPT SURG,SAN ANTONIO,TX 78284. AUDIE L MURPHY MEM VET ADM MED CTR,SAN ANTONIO,TX 78284. W VIRGINIA UNIV,MED CTR,SCH MED,DEPT SURG,MORGANTOWN,WV 26506. RP COHEN, DJ (reprint author), BROOKE ARMY MED CTR,HSHE SDC,CARDIOTHORAC SURG SERV,FT SAM HOUSTON,TX 78234, USA. NR 34 TC 3 Z9 3 U1 0 U2 0 PU BLACKWELL SCIENCE INC PI CAMBRIDGE PA 238 MAIN ST, CAMBRIDGE, MA 02142 SN 0160-564X J9 ARTIF ORGANS JI Artif. Organs PD DEC PY 1992 VL 16 IS 6 BP 614 EP 622 PG 9 WC Engineering, Biomedical; Transplantation SC Engineering; Transplantation GA KD657 UT WOS:A1992KD65700012 PM 1482332 ER PT J AU WILEY, RW KOTULAK, JC BEHAR, I AF WILEY, RW KOTULAK, JC BEHAR, I TI THE EFFECTS OF PYRIDOSTIGMINE BROMIDE ON VISUAL PERFORMANCE SO AVIATION SPACE AND ENVIRONMENTAL MEDICINE LA English DT Article ID CONTRAST; DESIGN AB The effects of pyridostigmine bromide (PB) on selected visual functions were measured an four healthy aviator candidates. Following a pretreatment day during which baseline measurements were completed, subjects were administered currently recommended doses (30 mg, t.i.d.) of PB for 3 d during which their visual functions were assessed using a repeated measures design. Spatial resolution ability was evaluated with high and low contrast visual acuity charts and contrast sensitivity charts at three luminance levels. Dark adaptation was evaluated by measuring visual thresholds for 40 min after a standardized retinal photopigment bleach. Also, refractive error and several oculomotor functions (lateral phoria, fusional vergence, accommodative amplitude, and pupil size) were measured. On days that the subjects ingested PB, only refractive error and pupil diameter were significantly different, and these only minimally. We conclude that the use of PB at doctrinal doses will not significantly compromise an aviator's visual ability. RP WILEY, RW (reprint author), USA,AEROMED RES LAB,DIV SENSORY RES,POB 577,FT RUCKER,AL 36362, USA. NR 21 TC 3 Z9 3 U1 0 U2 0 PU AEROSPACE MEDICAL ASSOC PI ALEXANDRIA PA 320 S HENRY ST, ALEXANDRIA, VA 22314-3579 SN 0095-6562 J9 AVIAT SPACE ENVIR MD JI Aviat. Space Environ. Med. PD DEC PY 1992 VL 63 IS 12 BP 1054 EP 1059 PG 6 WC Public, Environmental & Occupational Health; Medicine, General & Internal; Sport Sciences SC Public, Environmental & Occupational Health; General & Internal Medicine; Sport Sciences GA JZ881 UT WOS:A1992JZ88100002 PM 1456915 ER PT J AU LAM, DM AF LAM, DM TI KELLYS HOSPITAL SHIP SO AVIATION SPACE AND ENVIRONMENTAL MEDICINE LA English DT Note AB The JN-4 "Jennie" and DH-4 air ambulance conversions used by the U.S. Army during the period 1918-1924 are well-known to those interested in the history of air evacuation. However, another "unknown" craft was also used during this period. The author unravels the mystery of this craft converted for use as an air ambulance at Kelly Field, TX. RP LAM, DM (reprint author), USA,MED DEPT ACT,OFF COMMANDER,FT DEVENS,MA 01433, USA. NR 11 TC 1 Z9 1 U1 0 U2 0 PU AEROSPACE MEDICAL ASSOC PI ALEXANDRIA PA 320 S HENRY ST, ALEXANDRIA, VA 22314-3579 SN 0095-6562 J9 AVIAT SPACE ENVIR MD JI Aviat. Space Environ. Med. PD DEC PY 1992 VL 63 IS 12 BP 1115 EP 1117 PG 3 WC Public, Environmental & Occupational Health; Medicine, General & Internal; Sport Sciences SC Public, Environmental & Occupational Health; General & Internal Medicine; Sport Sciences GA JZ881 UT WOS:A1992JZ88100015 PM 1456927 ER PT J AU GALBICKA, G KAUTZ, MA RITCH, ZJ AF GALBICKA, G KAUTZ, MA RITCH, ZJ TI REINFORCEMENT LOSS AND BEHAVIORAL TOLERANCE TO D-AMPHETAMINE - USING PERCENTILE SCHEDULES TO CONTROL REINFORCEMENT DENSITY SO BEHAVIOURAL PHARMACOLOGY LA English DT Article DE AMPHETAMINE; LEVER PRESS; PERCENTILE SCHEDULES; RATS; REINFORCEMENT LOSS; RESPONSE DIFFERENTIATION; RESPONSE NUMBER; TOLERANCE ID CLONIDINE AB Two procedures were used to examine the impact of reinforcement loss on the development of behavioral tolerance to the effects of d-amphetamine on control over response number in rats. Under both procedures, trials consisted of at least one left-lever press followed by a single right-lever press. Consecutive left-lever presses on each trial comprised a ''run''. A targeted percentile schedule provided reinforcement if the current run length was closer to the target length (12) than two-thirds of the most recent 24 runs. This procedure differentially reinforced runs around 12 while holding reinforcement probability constant at 0.333. A second group acquired the differentiation under the percentile schedule, but was then shifted to a procedure which yoked reinforcement probability by subject and run length to that obtained under asymptotic percentile schedule performance. The two procedures generated roughly comparable, but not identical, control run lengths, response rates, reinforcement probabilities and reinforcement rates. Only under the yoked procedure, however, did drug-induced disruptions in run length produce decreases in reinforcement density. Acute administration of amphetamine produced dose-related decreases in run length and overall response rate under both procedures. Daily pre-session administration of 1.7 mg/kg amphetamine persistently suppressed run length under the percentile procedure, but not under the yoked procedure. Run lengths under the latter gradually increased with repeated amphetamine to a level equal to or slightly below baseline levels. Response rate was suppressed initially, and tolerance developed inconsistently to this effect in both groups. Dose-effect curves obtained when doses of amphetamine were substituted for the chronic dose showed a larger shift to the right with the yoked than percentile group for run length,and a similar but smaller effect for overall response rate. These results indicate that reinforcement loss substantially contributes to the development of tolerance to the behavioral effects of amphetamine, even when the comparison behaviors are generated by reinforcement contingencies that under non-drug conditions control verv similar rates and patterns of behavior and reinforcement. Future comparison of acute and chronic drug effects on behaviors maintained by the percentile and yoked procedures may prove verv helpful in illuminating drug-behavior interactions and the dynamic interrelations typically engendered by more traditional reinforcement schedules. RP GALBICKA, G (reprint author), WALTER REED ARMY INST RES,DEPT MED NEUROSCI,WASHINGTON,DC 20307, USA. NR 20 TC 7 Z9 7 U1 0 U2 0 PU RAPID SCIENCE PUBLISHERS PI LONDON PA 2-6 BOUNDARY ROW, LONDON, ENGLAND SE1 8NH SN 0955-8810 J9 BEHAV PHARMACOL JI Behav. Pharmacol. PD DEC PY 1992 VL 3 IS 6 BP 535 EP 544 PG 10 WC Behavioral Sciences; Neurosciences; Pharmacology & Pharmacy SC Behavioral Sciences; Neurosciences & Neurology; Pharmacology & Pharmacy GA KF080 UT WOS:A1992KF08000001 ER PT J AU BERNTON, E BRYANT, H HOLADAY, J DAVE, J AF BERNTON, E BRYANT, H HOLADAY, J DAVE, J TI PROLACTIN AND PROLACTIN SECRETAGOGUES REVERSE IMMUNOSUPPRESSION IN MICE TREATED WITH CYSTEAMINE, GLUCOCORTICOIDS, OR CYCLOSPORINE-A SO BRAIN BEHAVIOR AND IMMUNITY LA English DT Article ID LYMPHOCYTE-PROLIFERATION; PITUITARY PROLACTIN; GROWTH-HORMONE; RAT; INHIBITION; DEPLETION; CELLS; IMMUNOMODULATION; IMMUNOREGULATION; BROMOCRIPTINE C1 WALTER REED ARMY INST RES,DEPT MED NEUROSCI,DIV NEUROPSYCHIAT,WASHINGTON,DC 20307. RP BERNTON, E (reprint author), WALTER REED ARMY INST RES,DEPT BACTERIAL DIS,DIV CD&I,WASHINGTON,DC 20307, USA. NR 44 TC 38 Z9 38 U1 0 U2 0 PU ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 SN 0889-1591 J9 BRAIN BEHAV IMMUN JI Brain Behav. Immun. PD DEC PY 1992 VL 6 IS 4 BP 394 EP 408 DI 10.1016/0889-1591(92)90038-P PG 15 WC Immunology; Neurosciences SC Immunology; Neurosciences & Neurology GA KE831 UT WOS:A1992KE83100008 PM 1336994 ER PT J AU YANG, YC BAKER, JA WARD, JR AF YANG, YC BAKER, JA WARD, JR TI DECONTAMINATION OF CHEMICAL WARFARE AGENTS SO CHEMICAL REVIEWS LA English DT Review ID PHASE-TRANSFER CATALYSIS; PSEUDOMONAS-DIMINUTA; ORTHO-IODOSOBENZOATE; MUSTARD DERIVATIVES; PERACID OXIDATION; FLAVOBACTERIUM SP; HYDROLYSIS; PHOSPHOTRIESTERASE; PHOSPHORUS; MECHANISM RP YANG, YC (reprint author), USA,CRDEC,PHYS PROTECT DIRECTORATE,DIV DECONTAMINAT SYST,ABERDEEN PROVING GROUND,MD 21010, USA. NR 96 TC 675 Z9 685 U1 17 U2 104 PU AMER CHEMICAL SOC PI WASHINGTON PA 1155 16TH ST, NW, WASHINGTON, DC 20036 SN 0009-2665 J9 CHEM REV JI Chem. Rev. PD DEC PY 1992 VL 92 IS 8 BP 1729 EP 1743 DI 10.1021/cr00016a003 PG 15 WC Chemistry, Multidisciplinary SC Chemistry GA KE685 UT WOS:A1992KE68500003 ER PT J AU BRYAN, JP SJOGREN, MH LEGTERS, LJ PERINE, PL AF BRYAN, JP SJOGREN, MH LEGTERS, LJ PERINE, PL TI INTRADERMAL VACCINATION FOR HEPATITIS-B - REPLY SO CLINICAL INFECTIOUS DISEASES LA English DT Letter ID IMMUNOGENICITY C1 USA,MED RES INST INFECT DIS,DEPT MED,FT DETRICK,MD. RP BRYAN, JP (reprint author), UNIFORMED SERV UNIV HLTH SCI,DEPT PREVENT MED & BIOMETR,4301 JONES BRIDGE RD,BETHESDA,MD 20814, USA. NR 9 TC 1 Z9 1 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 1058-4838 J9 CLIN INFECT DIS JI Clin. Infect. Dis. PD DEC PY 1992 VL 15 IS 6 BP 1064 EP 1066 PG 3 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA JZ600 UT WOS:A1992JZ60000041 ER PT J AU BRASSARD, JM ANZUETO, A LEVINE, SM ANDRADE, F MAXWELL, LC LAWRENCE, RA JENKINSON, SG AF BRASSARD, JM ANZUETO, A LEVINE, SM ANDRADE, F MAXWELL, LC LAWRENCE, RA JENKINSON, SG TI EFFECTS OF NORMOBARIC HYPEROXIA IN RAT DIAPHRAGM FUNCTION SO CLINICAL RESEARCH LA English DT Meeting Abstract C1 UNIV TEXAS,HLTH SCI CTR,DEPT MED,SAN ANTONIO,TX 78284. UNIV TEXAS,HLTH SCI CTR,DEPT PHYSIOL,SAN ANTONIO,TX 78284. AUDIE L MURPHY VA HOSP,SAN ANTONIO,TX. BROOKE ARMY MED CTR,SAN ANTONIO,TX. RI Andrade, Francisco/F-1258-2011 OI Andrade, Francisco/0000-0002-2460-5798 NR 1 TC 0 Z9 0 U1 0 U2 0 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 SN 0009-9279 J9 CLIN RES JI Clin. Res. PD DEC PY 1992 VL 40 IS 4 BP A854 EP A854 PG 1 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA KE141 UT WOS:A1992KE14100451 ER PT J AU RASZKA, WV WHITE, CB SNOW, KG DRABICK, CJ FISCHER, GW AF RASZKA, WV WHITE, CB SNOW, KG DRABICK, CJ FISCHER, GW TI DIFFERENTIAL ABILITY OF LATEX AGGLUTINATION KITS TO DETECT 4 CONJUGATED HAEMOPHILUS-INFLUENZAE TYPE-B VACCINES IN URINE SO CLINICAL RESEARCH LA English DT Meeting Abstract C1 WALTER REED ARMY MED CTR,WASHINGTON,DC 20307. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 SN 0009-9279 J9 CLIN RES JI Clin. Res. PD DEC PY 1992 VL 40 IS 4 BP A787 EP A787 PG 1 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA KE141 UT WOS:A1992KE14100085 ER PT J AU MALEVSKY, AV YUEN, DA AF MALEVSKY, AV YUEN, DA TI LARGE-SCALE NUMERICAL SIMULATIONS OF TURBULENT NON-NEWTONIAN THERMAL-CONVECTION USING METHOD OF CHARACTERISTICS SO COMPUTER PHYSICS COMMUNICATIONS LA English DT Article; Proceedings Paper CT 9TH EUROPEAN SUMMER SCHOOL ON COMPUTING TECHNIQUES IN PHYSICS : NUMERICAL TECHNIQUES AND PARALLELISM IN PHYSICS CY SEP 10-20, 1991 CL SKALSKY DVUR, CZECHOSLOVAKIA SP EUROPEAN PHYS SOC, COMPUTAT PHYS GRP, USN, OFF NAVAL RES, SWISS NATL FUND SCI RES, GERMAN PHYS SOC ID INFINITE PRANDTL NUMBER AB We have applied a method of characteristics to a large-scale computational problem of strongly time-dependent, two-dimensional, incompressible, infinite Prandtl number thermal convection for a non-Newtonian power law rheology. Bicubic splines are used for the spatial discretization for both temperature and stream function fields. A predictor-corrector type scheme with the Lagrangian formulation of the total time derivative in the energy equation allows one to model flows with advection strongly dominating over diffusion. The non-Newtonian rheological law introduces nonlinearity into the momentum equation. Therefore, iterations are necessary to obtain the solution at each time step. This aspect is responsible for the very CPU intensive nature of this problem. Extrapolation of the stream function fields from the previous time steps gives a good initial guess. Thus only a few Picard iterations are usually necessary to obtain solution of the momentum equation. We have observed the transition from mildly time-dependent to the strongly chaotic or turbulent non-Newtonian convection. The regular cellular structure of convection is broken in turbulent regime. The thermal plumes become disconnected and the interior of the convecting volume is filled with the detached blobs of hot and cold material. Non-Newtonian convection is far more chaotic than Newtonian carrying away the same amount of heat from a box. Rising non-Newtonian plumes exhibit much greater curvature in their ascent than Newtonian ones and are strongly attracted by descending currents at the top. Increasing the power-law index sharpens the chaotic behavior of the flow. C1 UNIV MINNESOTA,ARMY HIGH PERFORMANCE COMP RES CTR,MINNESOTA SUPERCOMP INST,MINNEAPOLIS,MN 55455. UNIV MINNESOTA,DEPT GEOL & GEOPHYS,MINNEAPOLIS,MN 55455. NR 12 TC 6 Z9 6 U1 1 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0010-4655 J9 COMPUT PHYS COMMUN JI Comput. Phys. Commun. PD DEC PY 1992 VL 73 IS 1-3 BP 61 EP 71 DI 10.1016/0010-4655(92)90029-X PG 11 WC Computer Science, Interdisciplinary Applications; Physics, Mathematical SC Computer Science; Physics GA KG559 UT WOS:A1992KG55900006 ER PT J AU MITTAL, S TEZDUYAR, TE AF MITTAL, S TEZDUYAR, TE TI NOTES ON THE STABILIZED SPACE-TIME FINITE-ELEMENT FORMULATION OF UNSTEADY INCOMPRESSIBLE FLOWS SO COMPUTER PHYSICS COMMUNICATIONS LA English DT Article ID COMPUTATIONAL FLUID-DYNAMICS; EQUATIONS; ALGORITHM; SYSTEMS AB This paper gives a review of our research efforts on the stabilized space-time finite element formulation of unsteady incompressible flows, including those involving moving boundaries are interfaces. Iterative solution techniques employed to solve the equation systems resulting from the space-time finite element discretization of these flow problems are also reviewed. Results are presented for certain unsteady flow problems, including large-amplitude sloshing and flows past oscillating cylinders. C1 UNIV MINNESOTA, MINNESOTA SUPERCOMP INST, 1200 WASHINGTON AVE S, MINNEAPOLIS, MN 55415 USA. UNIV MINNESOTA, DEPT AEROSP ENGN & MECH, ARMY HIGH PERFORMANCE COMP RES CTR, MINNEAPOLIS, MN 55415 USA. RI Tezduyar, Tayfun/F-6134-2012 OI Tezduyar, Tayfun/0000-0001-8707-3162 NR 32 TC 10 Z9 10 U1 0 U2 2 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0010-4655 J9 COMPUT PHYS COMMUN JI Comput. Phys. Commun. PD DEC PY 1992 VL 73 IS 1-3 BP 93 EP 112 DI 10.1016/0010-4655(92)90031-S PG 20 WC Computer Science, Interdisciplinary Applications; Physics, Mathematical SC Computer Science; Physics GA KG559 UT WOS:A1992KG55900008 ER PT J AU MAEL, FA TETRICK, LE AF MAEL, FA TETRICK, LE TI IDENTIFYING ORGANIZATIONAL IDENTIFICATION SO EDUCATIONAL AND PSYCHOLOGICAL MEASUREMENT LA English DT Article ID COMMITMENT; GOODNESS; FIT AB Identification with a psychological group or organization (IDPG) is defined as the perception of sharing experiences of a focal group and sharing characteristics of the group's members. IDPG is conceptually distinct from the related concept of organizational commitment. In the present study with 263 employed persons, IDPG was shown to be empirically distinct from organizational commitment. In addition, IDPG was shown to have significantly less overlap than commitment with three related concepts: job satisfaction, organizational satisfaction, and job involvement. C1 WAYNE STATE UNIV,DETROIT,MI 48202. RP MAEL, FA (reprint author), USA,RES INST,ALEXANDRIA,VA 22217, USA. NR 39 TC 160 Z9 166 U1 5 U2 46 PU SAGE PUBLICATIONS INC PI THOUSAND OAKS PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 SN 0013-1644 J9 EDUC PSYCHOL MEAS JI Educ. Psychol. Meas. PD WIN PY 1992 VL 52 IS 4 BP 813 EP 824 DI 10.1177/0013164492052004002 PG 12 WC Psychology, Educational; Mathematics, Interdisciplinary Applications; Psychology, Mathematical SC Psychology; Mathematics GA KC758 UT WOS:A1992KC75800002 ER PT J AU CARR, FE FEIN, HG FISHER, CU WESSENDORF, MW SMALLRIDGE, RC AF CARR, FE FEIN, HG FISHER, CU WESSENDORF, MW SMALLRIDGE, RC TI A CRYPTIC PEPTIDE (160-169) OF THYROTROPIN-RELEASING-HORMONE PROHORMONE DEMONSTRATES BIOLOGICAL-ACTIVITY INVIVO AND INVITRO SO ENDOCRINOLOGY LA English DT Article ID BETA-SUBUNIT GENE; PROTEIN-KINASE-C; PITUITARY-CELLS; RAT-BRAIN; INTRACELLULAR CALCIUM; THYROID-HORMONE; PROLACTIN; PRECURSOR; TRH; IDENTIFICATION AB TRH is synthesized as a precursor peptide containing five copies of the sequence Gln-His-Pro-Gly, QHPG, flanked by paired basic amino acids, and linked by other peptides. We tested one cryptic peptide, PPT (160-169, SFPWMESDVT), as a possible physiological regulator of pituitary activity in vivo. Male rats were cannulated (jugular) and received a single dose of either PPT or TRH (10(-8)-10(-6) m). PPT caused no consistent effects on either TSH or PRL secretion, while TRH stimulated the secretion of both hormones. However, PPT stimulated a dose-dependent increase in both pituitary TSHbeta and PRL mRNA content at 240 min similar to TRH. In primary cultures of rat pituitaries, PPT stimulated a maximum 4-fold increase in TSHbeta mRNA and a 2-fold increase in PRL mRNA in 4 h, while TRH increased both TSHbeta and PRL mRNA approximately 3-fold. Again, PPT had no significant effect on TSH or PRL secretion into the medium. Thus, PPT appears to be a physiological regulator of both TSH and PRL synthesis, but, unlike TRH, does not act as a secretagogue. C1 WALTER REED ARMY INST RES, DEPT CLIN PHYSIOL, WASHINGTON, DC 20307 USA. UNIV MINNESOTA, DEPT NEUROANAT & CELL BIOL, MINNEAPOLIS, MN 55455 USA. RP CARR, FE (reprint author), WALTER REED ARMY MED CTR, DEPT CLIN INVEST, RES LABS, KYLE METAB UNIT, 6800 GEORGIA AVE, WASHINGTON, DC 20307 USA. NR 28 TC 19 Z9 19 U1 0 U2 0 PU ENDOCRINE SOC PI CHEVY CHASE PA 8401 CONNECTICUT AVE, SUITE 900, CHEVY CHASE, MD 20815-5817 USA SN 0013-7227 EI 1945-7170 J9 ENDOCRINOLOGY JI Endocrinology PD DEC PY 1992 VL 131 IS 6 BP 2653 EP 2658 DI 10.1210/en.131.6.2653 PG 6 WC Endocrinology & Metabolism SC Endocrinology & Metabolism GA KB068 UT WOS:A1992KB06800025 PM 1446607 ER EF