FN Thomson Reuters Web of Science™ VR 1.0 PT J AU DECOCK, KM GNAORE, E ADJORLOLO, G BRAUN, MM LAFONTAINE, MF YESSO, G BRETTON, G COULIBALY, IM GERSHYDAMET, GM BRETTON, R HEYWARD, WL AF DECOCK, KM GNAORE, E ADJORLOLO, G BRAUN, MM LAFONTAINE, MF YESSO, G BRETTON, G COULIBALY, IM GERSHYDAMET, GM BRETTON, R HEYWARD, WL TI RISK OF TUBERCULOSIS IN PATIENTS WITH HIV-I AND HIV-II INFECTIONS IN ABIDJAN, IVORY-COAST SO BRITISH MEDICAL JOURNAL LA English DT Article ID HUMAN IMMUNODEFICIENCY VIRUS; WEST-AFRICA; AIDS; TYPE-2 AB Objective - To examine the association between HIV-II infection and tuberculosis. Design - Cross sectional study comparing the prevalence of HIV-I and HIV-II infections in patients with tuberculosis and in blood donors. Setting - Abidjan, Ivory Coast, west Africa. Patients - 2043 consecutive ambulant patients with tuberculosis (confirmed pulmonary, presumed pulmonary, or extrapulmonary) and 2127 volunteer blood donors. Main outcome measure - Prevalence of HIV-I and HIV-II infections as assessed by presence of serum antibodies. Results - Overall rates of HIV infection were 40.2% in patients with tuberculosis (26.4% positive for HIV-I, 4.7% for HIV-II, and 9.0% for both); and 10.4% in blood donors (7.2% positive for HIV-I, 1.9% for HIV-II, and 1.3% for both). HIV-II infection was significantly more common in patients with all types of tuberculosis than in blood donors (97/2043, 4.7% v 40/2127, 1.9%; odds ratio 3.8%, 95% confidence interval 2.6 to 5.6). Conclusion - Both HIV-I and HIV-II infection are associated with tuberculosis in Abidjan. 35% of adult tuberculosis in Abidjan is attributable to HIV infection and 4% specifically to HIV-II. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV HIV & AIDS,ATLANTA,GA 30333. CTR ANTITB,ABIDJAN,COTE IVOIRE. INST PASTEUR COTE IVOIRE,ABIDJAN,COTE IVOIRE. RP DECOCK, KM (reprint author), PROJET RETRO CI,ABIDJAN,COTE IVOIRE. NR 18 TC 107 Z9 107 U1 0 U2 1 PU BRITISH MED JOURNAL PUBL GROUP PI LONDON PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON, ENGLAND WC1H 9JR SN 0959-8138 J9 BRIT MED J JI Br. Med. J. PD MAR 2 PY 1991 VL 302 IS 6775 BP 496 EP 499 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA FB055 UT WOS:A1991FB05500017 PM 1849431 ER PT J AU BLOLAND, PB REDD, SC KAZEMBE, P TEMBENU, R WIRIMA, JJ CAMPBELL, CC AF BLOLAND, PB REDD, SC KAZEMBE, P TEMBENU, R WIRIMA, JJ CAMPBELL, CC TI COTRIMOXAZOLE FOR CHILDHOOD FEBRILE ILLNESS IN MALARIA-ENDEMIC REGIONS SO LANCET LA English DT Note AB The efficacy of co-trimoxazole for the treatment of Plasmodium falciparum parasitaemia in children younger than 5 years of age was evaluated in Malawi. 46 children with P falciparum parasitaemia, 37% of whom also met clinical criteria for a diagnosis of acute lower respiratory tract infection, were treated with 20 mg/kg co-trimoxazole twice daily for five days. Parasitaemia (mean clearance time 2.7 days) and symptoms were rapidly abolished and improvement was maintained during follow-up for 14 days. Co-trimoxazole may be an effective single treatment for febrile illness in young children in areas where malaria is endemic, resources are few, and diagnosis must rely on clinical findings alone. C1 CTR DIS CONTROL,INT HLTH PROGRAM OFF,ATLANTA,GA 30333. MINIST HLTH,LILONGWE,MALAWI. RP BLOLAND, PB (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,MALARIA BRANCH,F-12,ATLANTA,GA 30333, USA. NR 7 TC 37 Z9 37 U1 0 U2 0 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD MAR 2 PY 1991 VL 337 IS 8740 BP 518 EP 520 DI 10.1016/0140-6736(91)91299-A PG 3 WC Medicine, General & Internal SC General & Internal Medicine GA EZ874 UT WOS:A1991EZ87400006 PM 1671892 ER PT J AU TANGERMANN, RH GORDON, S WIESNER, P KRECKMAN, L AF TANGERMANN, RH GORDON, S WIESNER, P KRECKMAN, L TI AN OUTBREAK OF CRYPTOSPORIDIOSIS IN A DAY-CARE-CENTER IN GEORGIA SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Article DE CRYPTOSPORIDIOSIS; DAY CARE; DIARRHEA ID IMMUNOCOMPETENT INDIVIDUALS; DIARRHEA; OOCYSTS AB Diarrhea among the 11 million children attending day-care centers in the United States is common, but infection control of enteric pathogens in the day-care center setting remains a challenge. In August 1989, an outbreak of cryptosporidiosis was investigated at a day-care center in Georgia. A total of 49% (39/79) of children and 13% (3/23) of staff members who submitted stool specimens were found to be infected with Cryptosporidium. A total of 77% (30/39) of infected children had mild-to-moderate diarrhea (median duration, 5 days). Children were at highest risk if they were less than age 36 months, in diapers, and not toilet trained. Serial stool specimens were collected from 12 infected children. After diarrhea had ceased, oocyst shedding continued in all children for a mean duration of 16.5 days. It is concluded that the prevalence of asymptomatic infections and the duration of shedding after the end of symptoms may previously have been underestimated. Cohorting or exclusion from the day-care center of children who are asymptomatic shedders is not practical, and the management of cryptosporidiosis in day-care centers remains a major challenge. C1 CTR DIS CONTROL,PREVENT MED RESIDENCY PROGRAM,ATLANTA,GA 30333. DEKALB CTY BOARD HLTH,DECATUR,GA. US DEPT HHS,STATE LAB,ATLANTA,GA 30333. RP TANGERMANN, RH (reprint author), UNIV DUSSELDORF,KINDERKLIN,SCHLOSSMANNHAUS,MOORENSTR 5,W-4000 DUSSELDORF 1,GERMANY. NR 17 TC 34 Z9 36 U1 0 U2 3 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD MAR 1 PY 1991 VL 133 IS 5 BP 471 EP 476 PG 6 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA FC050 UT WOS:A1991FC05000011 PM 2000857 ER PT J AU LIFSON, AR HESSOL, NA OMALLEY, PM BARNHART, JL DARROW, WW JAFFE, HW RUTHERFORD, GW AF LIFSON, AR HESSOL, NA OMALLEY, PM BARNHART, JL DARROW, WW JAFFE, HW RUTHERFORD, GW TI KAPOSIS-SARCOMA IN A COHORT OF HOMOSEXUAL AND BISEXUAL MEN - EPIDEMIOLOGY AND ANALYSIS FOR COFACTORS - REPLY SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Letter ID ACQUIRED IMMUNODEFICIENCY SYNDROME; AIDS C1 CALIF DEPT HLTH SERV,INFECT DIS BRANCH,BERKELEY,CA 94704. CTR DIS CONTROL,DIV HIV AIDS,ATLANTA,GA 30333. RP LIFSON, AR (reprint author), DEPT PUBL HLTH,AIDS OFF,SAN FRANCISCO,CA 94102, USA. NR 8 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD MAR 1 PY 1991 VL 133 IS 5 BP 515 EP 516 PG 2 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA FC050 UT WOS:A1991FC05000019 ER PT J AU MARSH, GM LEVITON, LC TALBOTT, EO CALLAHAN, C PAVLOCK, D HEMSTREET, G LOGUE, JN FOX, J SCHULTE, P AF MARSH, GM LEVITON, LC TALBOTT, EO CALLAHAN, C PAVLOCK, D HEMSTREET, G LOGUE, JN FOX, J SCHULTE, P TI DRAKE CHEMICAL WORKERS HEALTH REGISTRY STUDY .1. NOTIFICATION AND MEDICAL SURVEILLANCE OF A GROUP OF WORKERS AT HIGH-RISK OF DEVELOPING BLADDER-CANCER SO AMERICAN JOURNAL OF INDUSTRIAL MEDICINE LA English DT Article DE BETA-NAPHTHYLAMINE; AROMATIC AMINES; COHORT STUDY; HIGH RISK NOTIFICATION; CHEMICAL MANUFACTURE; OCCUPATIONAL MORTALITY RISKS ID AROMATIC-AMINES; SUPERFUND SITE; COHORT; PENNSYLVANIA; MORTALITY AB A medical surveillance program and epidemiologic study of 408 former workers of the Drake Chemical Company (now a Superfund waste site) was established in 1986. The Drake Health Registry Study was initiated because these workers had probable past exposures to beta-naphthylamine (BNA), a potent bladder carcinogen. The registry is widely viewed as a model for notification of workers at high risk of disease due to past occupational exposures. By the 40th month, 90% of the 366 living workers had been notified of the existence of the registry; 262 had been enrolled in the annual or semi-annual screening for bladder cancer. Among these, 27 persons have had abnormal screening results indicating moderate to high risk of bladder cancer and have been made eligible for further diagnostic tests. While no invasive bladder tumors were found among 18 persons completing the extended diagnostic evaluation, two diagnoses of moderate to severe dysplasia have been made. The registry has also identified three living and three deceased cases of bladder cancer in the cohort; a mortality analysis showed a 20- to 30-fold excess of bladder cancer. An incidence projection, based on the six identified cases, reveals that between six and ten new bladder cancer cases are likely to occur among the Drake cohort over the next 20 year period. C1 UNIV PITTSBURGH,GRAD SCH PUBL HLTH,CTR ENVIRONM EPIDEMIOL,PITTSBURGH,PA 15261. UNIV PITTSBURGH,GRAD SCH PUBL HLTH,DEPT HLTH SERV ADM,PITTSBURGH,PA 15261. UNIV PITTSBURGH,GRAD SCH PUBL HLTH,DEPT EPIDEMIOL,PITTSBURGH,PA 15261. UNIV PITTSBURGH,GRAD SCH PUBL HLTH,DEPT BIOSTAT,PITTSBURGH,PA 15261. LOCK HAVEN HOSP,LOCK HAVEN,PA. UNIV OKLAHOMA,HLTH SCI CTR,DEPT UROL,OKLAHOMA CITY,OK 73190. PENN DEPT HLTH,DIV ENVIRONM HLTH,HARRISBURG,PA. NIOSH,DIV SURVEILLANCE HAZARDOUS EVALUT & FIELD STUDIES,CINCINNATI,OH 45226. RP MARSH, GM (reprint author), UNIV PITTSBURGH,GRAD SCH PUBL HLTH,DEPT BIOSTAT,A412 CRABTREE HALL,130 DESOTO ST,PITTSBURGH,PA 15261, USA. NR 19 TC 17 Z9 17 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0271-3586 J9 AM J IND MED JI Am. J. Ind. Med. PD MAR PY 1991 VL 19 IS 3 BP 291 EP 301 DI 10.1002/ajim.4700190304 PG 11 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EX263 UT WOS:A1991EX26300003 PM 2008919 ER PT J AU KAHN, HS WILLIAMSON, DF STEVENS, JA AF KAHN, HS WILLIAMSON, DF STEVENS, JA TI RACE AND WEIGHT CHANGE IN UNITED-STATES WOMEN - THE ROLES OF SOCIOECONOMIC AND MARITAL-STATUS SO AMERICAN JOURNAL OF PUBLIC HEALTH LA English DT Article ID BODY-MASS INDEX; BLACK-WOMEN; ADULT WOMEN; OBESITY; HEALTH; OVERWEIGHT AB Background. The prevalence of overweight among Black women in the US is higher than among White women, but the causes are unknown. Methods. We examined the weight change for 514 Black and 2,770 White women who entered the first Health and Nutrition Examination Survey (1971-75) at ages 25-44 years and were weighed again a decade later. We used multivariate analyses to estimate the weight-change effects associated with race, family income, education, and marital change. Results. The mean weight change was greater for the Black women than the White women. Adjustments for height, duration of follow-up, baseline body mass index, and multiple demographic, social, and behavioral variables did not reduce this mean Black-White difference. Conclusions. Among US women, Black race is independently associated with a reduced likelihood of major weight loss, but not with major weight gain. Women at greatest risk of weight gain are those with education below college level, those entering marriage, and those with very low family income. C1 CTR DIS CONTROL,CTR CHRON DIS,DIV NUTR,MAIL STOP A41,PREVENT & HLTH PROMOT,ATLANTA,GA 30333. EMORY UNIV,SCH MED,DEPT COMMUNITY & PREVENT MED,ATLANTA,GA 30322. OI Kahn, Henry/0000-0003-2533-1562 NR 14 TC 120 Z9 120 U1 0 U2 2 PU AMER PUBLIC HEALTH ASSN INC PI WASHINGTON PA 1015 FIFTEENTH ST NW, WASHINGTON, DC 20005 SN 0090-0036 J9 AM J PUBLIC HEALTH JI Am. J. Public Health PD MAR PY 1991 VL 81 IS 3 BP 319 EP 323 DI 10.2105/AJPH.81.3.319 PG 5 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA FF473 UT WOS:A1991FF47300007 PM 2036117 ER PT J AU HERSH, BS MARKOWITZ, LE HOFFMAN, RE HOFF, DR DORAN, MJ FLEISHMAN, JC PREBLUD, SR ORENSTEIN, WA AF HERSH, BS MARKOWITZ, LE HOFFMAN, RE HOFF, DR DORAN, MJ FLEISHMAN, JC PREBLUD, SR ORENSTEIN, WA TI A MEASLES OUTBREAK AT A COLLEGE WITH A PREMATRICULATION IMMUNIZATION REQUIREMENT SO AMERICAN JOURNAL OF PUBLIC HEALTH LA English DT Article ID HIGHLY VACCINATED POPULATION; SCHOOL POPULATION; EPIDEMIC MEASLES; RISK-FACTORS; TRANSMISSION; EFFICACY; DISEASE AB Background. In early 1988 an outbreak of 84 measles cases occurred at a college in Colorado in which over 98 percent of students had documentation of adequate measles immunity (physician diagnosed measles, reciept of live measles vaccine on or after the first birthday, or serologic evidence of immunity) due to an immunization requirement in effect since 1986. Methods. To examine potential risk factors for measles vaccine failure, we conducted a retrospective cohort study among students living in campus dormitories using student health service vaccination records. Results. Overall, 70(83 percent) cases had been vaccinated at greater-than-or-equal-to 12 months of age. Students living in campus dormitories were at increased risk for measles compared to students living off-campus (RR = 3.0, 95% CI = 2.0, 4.7). Students vaccinated at 12-14 months of age were at increased risk compared to those vaccinated at greater-than-or-equal-to 15 months (RR = 3.1, 95% CI = 1.7, 5.7). Time since vaccination was not a risk factor for vaccine failure. Measles vaccine effectiveness was calculated to be 94% (95% CI = 86, 98) for vaccination at greater-than-or-equal-to 15 months. Conclusions. As in secondary schools, measles outbreaks can occur among highly vaccinated college populations. Implementation of recent recommendations to require two doses of measles vaccine for college entrants should help reduce measles outbreaks in college populations. C1 CTR DIS CONTROL,DIV IMMUNIZAT,ATLANTA,GA 30333. UNIV COLORADO,HLTH SCI CTR,DENVER,CO 80262. FT LEWIS COLL,STUDENT HLTH SERV,DURANGO,CO 81301. COLORADO DEPT HLTH,DENVER,CO. RP HERSH, BS (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,ATLANTA,GA 30333, USA. NR 29 TC 46 Z9 46 U1 1 U2 1 PU AMER PUBLIC HEALTH ASSN INC PI WASHINGTON PA 1015 FIFTEENTH ST NW, WASHINGTON, DC 20005 SN 0090-0036 J9 AM J PUBLIC HEALTH JI Am. J. Public Health PD MAR PY 1991 VL 81 IS 3 BP 360 EP 364 DI 10.2105/AJPH.81.3.360 PG 5 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA FF473 UT WOS:A1991FF47300013 PM 1994745 ER PT J AU BRAUN, MM BADI, N RYDER, RW BAENDE, E MUKADI, Y NSUAMI, M MATELA, B WILLAME, JC KABOTO, M HEYWARD, W AF BRAUN, MM BADI, N RYDER, RW BAENDE, E MUKADI, Y NSUAMI, M MATELA, B WILLAME, JC KABOTO, M HEYWARD, W TI A RETROSPECTIVE COHORT STUDY OF THE RISK OF TUBERCULOSIS AMONG WOMEN OF CHILDBEARING AGE WITH HIV-INFECTION IN ZAIRE SO AMERICAN REVIEW OF RESPIRATORY DISEASE LA English DT Article ID KINSHASA AB To determine the risk of active tuberculosis associated with HIV infection, we retrospectively studied a cohort of HIV-seropositive and HIV-seronegative women participating in an HIV perinatal transmission study in Kinshasa, Zaire. After a median follow-up of 32 months, new cases of proven pulmonary or clinically diagnosed tuberculosis occurred in 19 of the 249 HIV-seropositive women (7.6%, 3.1 cases per 100 person-years) compared with 1 of the 310 HIV-seronegative women (0.3%, 0.12 cases per 100 person-years), for a relative risk of 26 (95% confidence interval, 5 to 125). Proven pulmonary tuberculosis was diagnosed in 7 HIV-seropositive women (2.8%, 1.2 cases per 100 person-years) and 1 HIV-seronegative woman (0.3%, 0.12 cases per 100 person-years), for a relative risk of 10 (95% confidence interval, 1.5 to 47). We estimated that 66 cases of proven pulmonary tuberculosis in 100,000 person-years of follow-up in women of childbearing age could be attributed to HIV; this is 35% of their estimated total incidence of proven pulmonary tuberculosis. Among those followed for 2 yr, 27 (11%) of 243 HIV-seropositive women died during 2 yr of follow-up compared with none of 296 HIV-seronegative women (p < 0.001). In HIV-seropositive women with proven or clinically diagnosed tuberculosis mortality was even higher: 5 (26%) of the 19 HIV-seropositive women with proven pulmonary or clinically diagnosed tuberculosis died during follow-up compared with 22 (10%) of the 224 HIV-seropositive women not diagnosed as having tuberculosis (relative risk 2.7; 95% confidence interval, 1.1 to 6.3). This cohort study quantities the sizable contribution of the HIV/AIDS epidemic to increasing tuberculosis morbidity and mortality in a central African city. C1 CTR DIS CONTROL,CTR INFECT DIS,INT ACTIV DIV HIV AIDS,ATLANTA,GA 30333. DEPT SANTE PUBL,BUR NATL TB,CTR DEPISTAGE TB,KINSHASA,ZAIRE. NR 21 TC 100 Z9 101 U1 0 U2 1 PU AMER LUNG ASSOC PI NEW YORK PA 1740 BROADWAY, NEW YORK, NY 10019 SN 0003-0805 J9 AM REV RESPIR DIS JI Am. Rev. Respir. Dis. PD MAR PY 1991 VL 143 IS 3 BP 501 EP 504 PG 4 WC Respiratory System SC Respiratory System GA FA931 UT WOS:A1991FA93100009 PM 2001057 ER PT J AU COT, M GINESTE, B BARRO, D ROISIN, A YADA, A CARNEVALE, P AF COT, M GINESTE, B BARRO, D ROISIN, A YADA, A CARNEVALE, P TI COMPARISON OF 2 METHODS FOR FIELD ASSAY OF CHLOROQUINE IN URINE SO ANNALES DE LA SOCIETE BELGE DE MEDECINE TROPICALE LA French DT Article DE CHLOROQUINURIA; FIELD ASSAY; BERGQVIST METHOD; HMM II METHOD; BURKINA FASO ID METABOLITES AB Two methods of chloroquinuria assay were tested in pregnant women in the town of Banfora (Burkina Faso): the method with bromothymol blue (Bergqvist) and the method with methyl-orange (Haskins and Mount or HMM II). Urinary assay of chloroquine was performed with both methods in 45 women chosen at random whether or not under chemoprophylactic treatment (21 taking a weekly prophylaxis of 300 mg of chloroquine, and 24 controls). The HMM II method proved to be more sensitive (100 %) and more specific (91,7 %) than the Bergqvist method (80,9 % and 83,3 % respectively); it was also more reliable with regard to positive (91,3 % versus 80,9 %) and negative (100 % versus 91,3 %) predictive values. Moreover, the quantitative appreciation of the levels of chloroquine excretion proved to be superior with the HMM II method. Finally, this method is faster to perform, easier to use and cheaper, making it the method of choice for field assay of chloroquine in urine. C1 UNIV PARIS 07,INSERM,U155,F-75221 PARIS 05,FRANCE. ANTENNE ORSTOM AUPRES CTR MURAZ,BOBO DIOULASSO,BURKINA FASO. CTR DIS CONTROL,PROJECT CCCD,ATLANTA,GA 30333. DIRECT PROV SANTE,COMOE,BURKINA FASO. NR 4 TC 6 Z9 6 U1 0 U2 0 PU N V CEUTERICK PI LOUVAIN PA BRUSSELSESTRAAT 153, B-3000 LOUVAIN, BELGIUM SN 0365-6527 J9 ANN SOC BELG MED TR JI Ann. Soc. Belg. Med. Trop. PD MAR PY 1991 VL 71 IS 1 BP 17 EP 25 PG 9 WC Tropical Medicine SC Tropical Medicine GA FJ756 UT WOS:A1991FJ75600004 PM 2042997 ER PT J AU DOCK, NL KLEINMAN, SH RAYFIELD, MA SCHABLE, CA WILLIAMS, AE DODD, RY AF DOCK, NL KLEINMAN, SH RAYFIELD, MA SCHABLE, CA WILLIAMS, AE DODD, RY TI HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION AND INDETERMINATE WESTERN-BLOT PATTERNS - PROSPECTIVE STUDIES IN A LOW PREVALENCE POPULATION SO ARCHIVES OF INTERNAL MEDICINE LA English DT Article ID IMMUNOBLOT REACTIVITY; ANTIBODIES; DONORS; TYPE-1; IMMUNOASSAY; ASSAY AB Interpretation of human immunodeficiency virus (HIV) antibody results that are "indeterminate" rather than clearly positive or negative is problematic for the person delivering the result as well as for the individual being tested. To improve counseling messages for these individuals, we evaluated data collected from a well-characterized cohort of 387 blood donors who had been monitored for up to 2 years. We sought to determine if persons with indeterminate Western blot patterns were infected with HIV, and whether information derived from follow-up monitoring would assist in the development of counseling messages for persons on whom no follow-up information was available. Donors were studied by laboratory assays, clinical evaluation, and assessment of risk for HIV. The absence of HIV infection in 97 of 98 donors with indeterminate Western blot patterns was confirmed by clinical follow-up, Western blot assays of sequential samples, and negative gene amplification results. We propose supplemental guidelines to be used as an adjunct to existing interpretive criteria for counseling individuals when they first present with an indeterminate Western blot finding. C1 AMER RED CROSS BLOOD SERV,LOS ANGELES,CA. AMER RED CROSS,JEROME H HOLLAND LAB BIOMED SCI,ROCKVILLE,MD. CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,ATLANTA,GA 30333. RP DOCK, NL (reprint author), AMER RED CROSS,BLOOD SERV,RES & DEV LAB,636 S WARREN ST,SYRACUSE,NY 13202, USA. NR 26 TC 44 Z9 46 U1 0 U2 1 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0003-9926 J9 ARCH INTERN MED JI Arch. Intern. Med. PD MAR PY 1991 VL 151 IS 3 BP 525 EP 530 DI 10.1001/archinte.151.3.525 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA FA768 UT WOS:A1991FA76800014 PM 2001135 ER PT J AU PHILEN, RM EIDSON, M KILBOURNE, EM SEWELL, CM VOORHEES, R AF PHILEN, RM EIDSON, M KILBOURNE, EM SEWELL, CM VOORHEES, R TI EOSINOPHILIA-MYALGIA-SYNDROME - A CLINICAL CASE SERIES OF 21 PATIENTS SO ARCHIVES OF INTERNAL MEDICINE LA English DT Article AB We reviewed 21 cases of eosinophilia-myalgia syndrome to describe the range of clinical findings in these patients. Most patients were women (20 [95%]) and middle-aged (mean, 46 years) and had taken the food supplement L-tryptophan (95%). All cases involved eosinophilia (eosinophil count, greater-than-or-equal-to 2.0 x 10(9)/L) and incapacitating myalgias. Fourteen (88%) of the 16 patients tested had mild liver function abnormalities. Aldolase levels were abnormal in all patients tested. Muscle biopsies were done in five patients; four showed eosinophilic perimyositis, and one had interstitial inflammation. No physical finding was pathognomonic or universal, but muscle tenderness, tachycardia, and rash were the most common signs found during physical examinations. Seven patients were treated with prednisone, and six showed improvement in muscle pain and a decrease in eosinophilia. The cause of this disorder is still unknown. C1 NEW MEXICO HLTH & ENVIRONM DEPT,OFF EPIDEMIOL,SANTA FE,NM. RP PHILEN, RM (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,MAILSTOP F-28,ATLANTA,GA 30333, USA. NR 21 TC 37 Z9 37 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0003-9926 J9 ARCH INTERN MED JI Arch. Intern. Med. PD MAR PY 1991 VL 151 IS 3 BP 533 EP 537 DI 10.1001/archinte.151.3.533 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA FA768 UT WOS:A1991FA76800015 PM 2001136 ER PT J AU FREEDMAN, DS OBRIEN, TR FLANDERS, WD DESTEFANO, F BARBORIAK, JJ AF FREEDMAN, DS OBRIEN, TR FLANDERS, WD DESTEFANO, F BARBORIAK, JJ TI RELATION OF SERUM TESTOSTERONE LEVELS TO HIGH-DENSITY-LIPOPROTEIN CHOLESTEROL AND OTHER CHARACTERISTICS IN MEN SO ARTERIOSCLEROSIS AND THROMBOSIS LA English DT Article DE HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TESTOSTERONE; BLACKS ID HORMONE-BINDING GLOBULIN; CORONARY-ARTERY DISEASE; SEX-HORMONES; MYOCARDIAL-INFARCTION; PLASMA TESTOSTERONE; HEART-DISEASE; ESTRADIOL; HYPERESTROGENEMIA; ATHEROSCLEROSIS; APOLIPOPROTEINS AB Although levels of high density lipoprotein (HDL) cholesterol in males decrease during adolescence and after treatment with testosterone derivatives, several studies have reported that levels of HDL cholesterol are positively associated with endogenous levels of testosterone in men. This association was further examined using data collected during 1985 and 1986 from 3,562 white and 500 black men who ranged in age from 31 to 45 years. Black men had higher mean levels of both HDL cholesterol (8 mg/dl) and total testosterone (33 ng/dl) than white men, and positive associations were observed between testosterone and HDL cholesterol levels (r = 0.22, whites; r = 0.26, blacks). In addition, levels of testosterone were related positively to alcohol consumption and cigarette smoking and negatively to age, Quetelet index, and use of beta-blockers. We used stratification and regression analyses to determine if any of these characteristics could account for the positive association between levels of HDL cholesterol and total testosterone. Although controlling for most factors had little influence, adjusting for Quetelet index reduced the strength of the association between levels of testosterone and HDL cholesterol by approximately 30%. These findings suggest that the positive association between levels of testosterone and HDL cholesterol may not be causal. Multivariable analyses that control for obesity and other potentially confounding characteristics should be used in studies that assess the relation of testosterone levels to coronary heart disease. C1 CTR DIS CONTROL,CTR INFECT DIS,ATLANTA,GA 30333. MED COLL WISCONSIN,DEPT PHARMACOL & TOXICOL,MILWAUKEE,WI 53226. RP FREEDMAN, DS (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,AGENT ORANGE PROJECTS,A-41,ATLANTA,GA 30333, USA. NR 46 TC 54 Z9 55 U1 1 U2 1 PU AMER HEART ASSOC PI DALLAS PA 7272 GREENVILLE AVENUE, DALLAS, TX 75231-4596 SN 1049-8834 J9 ARTERIOSCLER THROMB JI Arterioscler. Thromb. PD MAR-APR PY 1991 VL 11 IS 2 BP 307 EP 315 PG 9 WC Cardiac & Cardiovascular Systems; Peripheral Vascular Disease SC Cardiovascular System & Cardiology GA FC067 UT WOS:A1991FC06700011 PM 1998648 ER PT J AU FLOYD, RL ZAHNISER, SC GUNTER, EP KENDRICK, JS AF FLOYD, RL ZAHNISER, SC GUNTER, EP KENDRICK, JS TI SMOKING DURING PREGNANCY - PREVALENCE, EFFECTS, AND INTERVENTION STRATEGIES SO BIRTH-ISSUES IN PERINATAL CARE LA English DT Article ID FETAL BLOOD-FLOW; MATERNAL SMOKING; CIGARETTE-SMOKING; BIRTH-WEIGHT; SPONTANEOUS-ABORTION; RANDOMIZED TRIAL; GROWTH; RISK; MORTALITY; DRINKING AB Smoking prevalence rates have been declining in the United States, but an estimated 25 percent of pregnant women continue to smoke. Smoking during pregnancy is considered one of the leading, preventable causes of low birthweight. Research attributes 21 to 39 percent of low birthweight to smoking during pregnancy, although the exact mechanism of the effect is not completely understood. Several well-designed studies have shown that pregnant smokers are more likely to stop smoking if they are provided with systematic interventions. This overview describes adverse consequences, prevalence, possible mechanisms of action, and prenatal smoking-cessation programs that have proved effective. A five-step approach is outlined for clinicians who want to counsel their prenatal clients. C1 CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV REPROD HLTH,ATLANTA,GA 30333. CTR DIS CONTROL,SMOKING CESSATION PREGNANCY PROJECT,ATLANTA,GA 30333. NR 47 TC 35 Z9 35 U1 0 U2 0 PU BLACKWELL SCIENCE INC PI CAMBRIDGE PA 238 MAIN ST, CAMBRIDGE, MA 02142 SN 0730-7659 J9 BIRTH-ISS PERINAT C JI Birth-Issue Perinat. Care PD MAR PY 1991 VL 18 IS 1 BP 48 EP 53 DI 10.1111/j.1523-536X.1991.tb00054.x PG 6 WC Nursing; Obstetrics & Gynecology; Pediatrics SC Nursing; Obstetrics & Gynecology; Pediatrics GA FE165 UT WOS:A1991FE16500011 PM 2006962 ER PT J AU SMITH, SJ MYERS, GL AF SMITH, SJ MYERS, GL TI ANALYZING QUALITY-CONTROL TRENDS WITH MOVING SLOPE CHARTS SO CLINICAL CHEMISTRY LA English DT Article DE TRENDS RULES COMPARED; CHOLESTEROL ID SHEWHART AB We have developed and evaluated a new procedure for detecting trends in quality-control measurements and applied it to laboratory data. The method requires the use of sequential or "moving" slope estimates to identify trends. Formulae are derived to estimate the regression error for the moving slope directly from the standard deviation of the analytical measurements obtained during characterization runs. Control limits for the moving slope depend only on this regression error, the span of the slope, and the desired statistical level of control. The moving slope can be plotted with control limits to determine out-of-control points. The statistical power of the moving slope is found to be much greater than that of an often-used test for trends. An example of the use of the moving slope is shown for quality-control measurements for total cholesterol obtained over several years. We conclude that the moving slope procedure has considerably more statistical power than trend rules and that it yields more useful information to the analyst. RP SMITH, SJ (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV ENVIRONM HLTH LAB SCI,ATLANTA,GA 30333, USA. NR 13 TC 4 Z9 4 U1 0 U2 0 PU AMER ASSOC CLINICAL CHEMISTRY PI WASHINGTON PA 2101 L STREET NW, SUITE 202, WASHINGTON, DC 20037-1526 SN 0009-9147 J9 CLIN CHEM JI Clin. Chem. PD MAR PY 1991 VL 37 IS 3 BP 341 EP 346 PG 6 WC Medical Laboratory Technology SC Medical Laboratory Technology GA FB914 UT WOS:A1991FB91400007 PM 2004440 ER PT J AU REIBNEGGER, G SPIRA, TJ FUCHS, D WERNERFELMAYER, G DIERICH, MP WACHTER, H AF REIBNEGGER, G SPIRA, TJ FUCHS, D WERNERFELMAYER, G DIERICH, MP WACHTER, H TI INDIVIDUAL PROBABILITY FOR ONSET OF FULL-BLOWN DISEASE IN PATIENTS INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 SO CLINICAL CHEMISTRY LA English DT Article DE ACQUIRED IMMUNE DEFICIENCY SYNDROME; NEOPTERIN; T-CELLS; POSTTEST PROBABILITIES AND RISK ESTIMATES; STATISTICS ID IMMUNE-DEFICIENCY SYNDROME; LYMPHADENOPATHY-ASSOCIATED VIRUS; B-CELL ACTIVATION; PREDICTIVE MARKER; URINARY NEOPTERIN; HOMOSEXUAL MEN; LYMPHOCYTE SUBSETS; AIDS; ABNORMALITIES; RISK AB Increased concentrations of neopterin, a marker for cell-mediated immune activation, and decreased numbers of CD4+ T cells, are predictors for progression of disease after infection with human immunodeficiency virus type 1. Previous studies have demonstrated different rates of onset of full-blown acquired immunodeficiency syndrome (AIDS) for groups of patients, defined by laboratory marker values, who were initially symptom-free. By reanalysis of one such study, we demonstrate how for an individual patient, the individual marker values, together with a prior risk estimate, can be converted into current or accumulated post-test probability of onset of AIDS at a certain time. We used a statistical technique suggested by Albert et al. (Clin Chem 1984;30:69-76), which allows incorporation of fixed and time-dependent covariates. Besides allowing individual projections, the method shows that the predictive abilities of CD4+ T cell numbers and of neopterin concentrations do not vary greatly with regard to time of observation; both laboratory markers independently modulate the underlying prior probability of AIDS onset, which is significantly increased with the passage of time. C1 INST MED CHEM & BIOCHEM,FRITZ PREGL STR 3,A-6020 INNSBRUCK,AUSTRIA. LUDWIG BOLTZMANN INST AIDS RES,INNSBRUCK,AUSTRIA. INST HYG,INNSBRUCK,AUSTRIA. CTR DIS CONTROL,CTR INFECT DIS,DIV HOST FACTORS,ATLANTA,GA 30333. RI Reibnegger, Gilbert/H-5742-2012 OI Reibnegger, Gilbert/0000-0001-7202-2426 NR 27 TC 6 Z9 6 U1 0 U2 0 PU AMER ASSOC CLINICAL CHEMISTRY PI WASHINGTON PA 2101 L STREET NW, SUITE 202, WASHINGTON, DC 20037-1526 SN 0009-9147 J9 CLIN CHEM JI Clin. Chem. PD MAR PY 1991 VL 37 IS 3 BP 351 EP 355 PG 5 WC Medical Laboratory Technology SC Medical Laboratory Technology GA FB914 UT WOS:A1991FB91400009 PM 2004442 ER PT J AU SALTZMAN, LE AF SALTZMAN, LE TI POLICING DOMESTIC VIOLENCE - WOMEN, THE LAW AND THE STATE - EDWARDS,SSM SO CONTEMPORARY SOCIOLOGY-A JOURNAL OF REVIEWS LA English DT Book Review RP SALTZMAN, LE (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU AMER SOCIOLOGICAL ASSOC PI WASHINGTON PA 1722 N ST NW, WASHINGTON, DC 20036-2981 SN 0094-3061 J9 CONTEMP SOCIOL JI Contemp. Sociol.-J. Rev. PD MAR PY 1991 VL 20 IS 2 BP 270 EP 271 DI 10.2307/2072971 PG 2 WC Sociology SC Sociology GA FF140 UT WOS:A1991FF14000094 ER PT J AU LUFT, BJ CASTRO, KG AF LUFT, BJ CASTRO, KG TI AN OVERVIEW OF THE PROBLEM OF TOXOPLASMOSIS AND PNEUMOCYSTOSIS IN AIDS IN THE USA - IMPLICATION FOR FUTURE THERAPEUTIC TRIALS SO EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES LA English DT Note ID ACQUIRED IMMUNODEFICIENCY SYNDROME AB By the end of 1989, 18,518 cases of Pneumocystis carinii infection and 5,614 cases of Toxoplasma gondii infection were reported to the Centers for Disease Control as the AIDS indicator disease. Pneumocystosis did not vary according to gender, race or risk factors; whereas toxoplasmosis was more common in black males with no known risk factors. Immigrants to the USA from Africa, Latin America and Haiti are three to four times more likely to develop toxoplasmic encephalitis than American-born patients with AIDS. The implications of this epidemiologic data for the predictive value of serology and clinical trials are discussed. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,EPIDEMIOL BRANCH,ATLANTA,GA 30333. RP LUFT, BJ (reprint author), SUNY STONY BROOK,HLTH SCI CTR,DEPT MED,DIV INFECT DIS,T-15 080,STONY BROOK,NY 11794, USA. OI Luft, Benjamin/0000-0001-9008-7004 NR 6 TC 17 Z9 17 U1 0 U2 0 PU FRIEDR VIEWEG SOHN VERLAG GMBH PI WIESBADEN 1 PA PO BOX 5829, W-6200 WIESBADEN 1, GERMANY SN 0934-9723 J9 EUR J CLIN MICROBIOL JI Eur. J. Clin. Microbiol. Infect. Dis. PD MAR PY 1991 VL 10 IS 3 BP 178 EP 181 DI 10.1007/BF01964455 PG 4 WC Infectious Diseases; Microbiology SC Infectious Diseases; Microbiology GA FK308 UT WOS:A1991FK30800010 PM 2060523 ER PT J AU HENSHAW, SK KOONIN, LM SMITH, JC AF HENSHAW, SK KOONIN, LM SMITH, JC TI CHARACTERISTICS OF UNITED-STATES WOMEN HAVING ABORTIONS, 1987 SO FAMILY PLANNING PERSPECTIVES LA English DT Article C1 CTR DIS CONTROL,DIV REPROD HLTH,STAT & COMP RESOURCES BRANCH,SURVEILLANCE UNIT,ATLANTA,GA 30333. RP HENSHAW, SK (reprint author), ALAN GUTTMACHER INST,NEW YORK,NY, USA. NR 20 TC 45 Z9 45 U1 0 U2 0 PU ALAN GUTTMACHER INST PI NEW YORK PA 120 WALL STREET, NEW YORK, NY 10005 SN 0014-7354 J9 FAM PLANN PERSPECT JI Fam. Plann. Perspect. PD MAR-APR PY 1991 VL 23 IS 2 BP 75 EP 81 DI 10.2307/2135453 PG 7 WC Demography; Family Studies SC Demography; Family Studies GA FJ379 UT WOS:A1991FJ37900004 PM 2060615 ER PT J AU ENG, E NAIMOLI, J NAIMOLI, G PARKER, KA LOWENTHAL, N AF ENG, E NAIMOLI, J NAIMOLI, G PARKER, KA LOWENTHAL, N TI THE ACCEPTABILITY OF CHILDHOOD IMMUNIZATION TO TOGOLESE MOTHERS - A SOCIOBEHAVIORAL PERSPECTIVE SO HEALTH EDUCATION QUARTERLY LA English DT Article ID FOCUS; PROGRAM C1 CTR DIS CONTROL,INT HLTH PROGRAM OFF,ATLANTA,GA 30333. RP ENG, E (reprint author), UNIV N CAROLINA,SCH PUBL HLTH,DEPT HLTH BEHAV & HLTH EDUC,CB 7400,CHAPEL HILL,NC 27599, USA. FU FDA HHS [BAF-0421-PHC-2233] NR 32 TC 13 Z9 13 U1 0 U2 0 PU SAGE SCIENCE PRESS PI THOUSAND OAKS PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 SN 0195-8402 J9 HEALTH EDUC QUART JI Health Educ. Q. PD SPR PY 1991 VL 18 IS 1 BP 97 EP 110 DI 10.1177/109019819101800110 PG 14 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA FA891 UT WOS:A1991FA89100010 PM 2037506 ER PT J AU KING, CH FIELDS, BS SHOTTS, EB WHITE, EH AF KING, CH FIELDS, BS SHOTTS, EB WHITE, EH TI EFFECTS OF CYTOCHALASIN-D AND METHYLAMINE ON INTRACELLULAR GROWTH OF LEGIONELLA-PNEUMOPHILA IN AMEBAS AND HUMAN MONOCYTE-LIKE CELLS SO INFECTION AND IMMUNITY LA English DT Article ID CHLAMYDIA-TRACHOMATIS; ALVEOLAR MACROPHAGES; ENTAMOEBA-HISTOLYTICA; SHIGELLA-FLEXNERI; HELA-CELLS; GUINEA-PIG; PHAGOCYTOSIS; ENDOCYTOSIS; AMEBAS; VIRULENCE AB A cloned and axenically cultured strain of Hartmannella vermiformis was used as a model to study intracellular multiplication of Legionella pneumophila in amoebae. The growth of L. pneumophila in both H. vermiformis and a human monocyte-like cell line (U937) was investigated with cytoskeletal and metabolic inhibitors. L. pneumophila replicated only intracellularly in these cellular models, and electron microscopy showed ultrastructural similarities in the initial phases of multiplication. Treatment of amoebae with an inhibitor of microfilament-dependent phagocytosis (cytochalasin D, 0.5 or 1.0-mu-g/ml) did not inhibit intracellular growth of L. pneumophila; however, intracellular multiplication was inhibited by treatment of U937 monocytes with the same concentrations of cytochalasin D. Methylamine (10 to 100 mM), an inhibitor of adsorptive pinocytosis, inhibited the replication of L. pneumophila in amoebae in a dose-dependent manner. All doses of methylamine tested (10 to 50 mM) inhibited growth of L. pneumophila in U937 monocytes. Cytochalasin D and methylamine had no effect on the multiplication of L. pneumophila in culture medium or on the viability of amoebae or U937 monocytes. Intracellular replication of L. pneumophila in H. vermiformis may be accomplished by a cytochalasin D-independent mechanism, such as adsorptive pinocytosis. In contrast, both cytochalasin D- and methylamine-sensitive mechanisms may be essential for the intracellular multiplication of L. pneumophila in U937 monocytes. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL & MYCOT DIS,RESP DIS BRANCH,ATLANTA,GA 30333. CTR DIS CONTROL,DIV HOST FACTORS,EXPTL PATHOL BRANCH,ATLANTA,GA 30333. UNIV GEORGIA,COLL VET MED,DEPT MED MICROBIOL,ATHENS,GA 30602. NR 43 TC 66 Z9 66 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0019-9567 J9 INFECT IMMUN JI Infect. Immun. PD MAR PY 1991 VL 59 IS 3 BP 758 EP 763 PG 6 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA EZ572 UT WOS:A1991EZ57200003 PM 1997428 ER PT J AU SCHABLE, B VILLARINO, ME FAVERO, MS MILLER, JM AF SCHABLE, B VILLARINO, ME FAVERO, MS MILLER, JM TI APPLICATION OF MULTILOCUS ENZYME ELECTROPHORESIS TO EPIDEMIOLOGIC INVESTIGATIONS OF XANTHOMONAS-MALTOPHILIA SO INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY LA English DT Article ID DIVERSITY AB OBJECTIVE: To test the utility of a newly developed multilocus enzyme electrophoresis typing method for Xanthomonas maltophilia. DESIGN: Isolates were first screened by slide agglutination, which served as the standard to characterize the outbreak strains. All isolates were then subjected to multilocus enzyme electrophoresis and the results analyzed based on epidemiological data. SETTING: This outbreak occurred in a shock-trauma intensive care unit of a large general community hospital. PATIENTS: Patients admitted to the shock-trauma intensive care unit who had X maltophilia isolated from any site greater-than-or-equal-to 24 hours after admission met the case definition. Specimens from patients who fit the case definition were characterized, as were specimens from other patients that were used as controls for nonoutbreak isolates. Environmental samples were also evaluated for X maltophilia. RESULTS: Most of the 64 isolates received during this outbreak were serotype 10, and when they were subjected to multilocus enzyme electrophoresis, one electrophoretic type predominated and correlated to most outbreak isolates. Unrelated isolates of serotype 10 from other institutions all exhibited unique electrophoretic types. CONCLUSION: Application of multilocus enzyme electrophoresis to X maltophilia outbreaks is a valuable addition to the characterization of suspected outbreak strains. RP SCHABLE, B (reprint author), CTR DIS CONTROL,HOSP INFECT PROGRAM,NOSOCOMIAL INFECT LAB BRANCH,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 10 TC 19 Z9 20 U1 0 U2 1 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 SN 0899-823X J9 INFECT CONT HOSP EP JI Infect. Control Hosp. Epidemiol. PD MAR PY 1991 VL 12 IS 3 BP 163 EP 167 PG 5 WC Public, Environmental & Occupational Health; Infectious Diseases SC Public, Environmental & Occupational Health; Infectious Diseases GA FZ115 UT WOS:A1991FZ11500010 PM 2022862 ER PT J AU SNIEZEK, JE SMITH, SM AF SNIEZEK, JE SMITH, SM TI INJURY MORTALITY AMONG NON-UNITED-STATES RESIDENTS IN THE UNITED-STATES 1979-1984 SO INTERNATIONAL JOURNAL OF EPIDEMIOLOGY LA English DT Article AB More than 20 million non-US resident visit the United States each year. Data on deaths in this country among these non-US residents were obtained from US vital records. These data showed that from 1979 through 1984, 17 988 deaths occurred. Cardiovascular disease (International Classification of Disease [ICD-9] 390-459) was the leading cause of death among non-residents. Injuries (ICD-9 E800-E999) ranked second as a cause of death and accounted for 23% of the deaths (4078). More than half of these injury deaths occurred among people aged 15-34 years and 79% of the people who died from injuries were males. The most frequent causes of injury deaths were motor vehicle traffic crashes (37%), drownings (15%), and homicides (11%). Although general patterns of injury mortality among non-US residents and US residents were similar, there were differences in the proportion of deaths due to homicides, drownings, and falls. Prevention efforts targeted to the major causes of injury mortality in the US will affect both US and non-US residents. RP SNIEZEK, JE (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV INJURY CONTROL,ATLANTA,GA 30333, USA. NR 11 TC 8 Z9 8 U1 0 U2 0 PU OXFORD UNIV PRESS UNITED KINGDOM PI OXFORD PA WALTON ST JOURNALS DEPT, OXFORD, ENGLAND OX2 6DP SN 0300-5771 J9 INT J EPIDEMIOL JI Int. J. Epidemiol. PD MAR PY 1991 VL 20 IS 1 BP 225 EP 229 DI 10.1093/ije/20.1.225 PG 5 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA FK354 UT WOS:A1991FK35400034 PM 2066225 ER PT J AU CATES, W AF CATES, W TI TEENAGERS AND SEXUAL RISK-TAKING - THE BEST OF TIMES AND THE WORST OF TIMES SO JOURNAL OF ADOLESCENT HEALTH LA English DT Article DE SEXUAL BEHAVIOR; SEXUALLY TRANSMITTED DISEASE; ADOLESCENT SEXUALITY; PREVENTION OF ADOLESCENT SEXUALLY TRANSMITTED DISEASE ID PELVIC INFLAMMATORY DISEASE; HUMAN PAPILLOMAVIRUS INFECTION; UNITED-STATES; TRANSMITTED DISEASES; GENITAL HERPES; EPIDEMIOLOGY; ADOLESCENTS; GONORRHEA; KNOWLEDGE; WOMEN RP CATES, W (reprint author), CTR DIS CONTROL,DIV SEXUALLY TRANSMITTED DIS,HIV PREVENT SERV,ATLANTA,GA 30333, USA. NR 55 TC 62 Z9 62 U1 3 U2 4 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 1054-139X J9 J ADOLESCENT HEALTH JI J. Adolesc. Health PD MAR PY 1991 VL 12 IS 2 BP 84 EP 94 DI 10.1016/0197-0070(91)90449-V PG 11 WC Psychology, Developmental; Public, Environmental & Occupational Health; Pediatrics SC Psychology; Public, Environmental & Occupational Health; Pediatrics GA EZ532 UT WOS:A1991EZ53200004 PM 2015246 ER PT J AU SCHRADER, SM TURNER, TW SIMON, SD AF SCHRADER, SM TURNER, TW SIMON, SD TI LONGITUDINAL-STUDY OF SEMEN QUALITY OF UNEXPOSED WORKERS SPERM MOTILITY CHARACTERISTICS SO JOURNAL OF ANDROLOGY LA English DT Article DE CURVILINEAR VELOCITY; STRAIGHT-LINE VELOCITY; COMPUTER-ASSISTED SPERM ANALYSIS (CASA); SOURCES OF VARIATION; STATISTICAL MODEL; REPEATABILITY ID MOVEMENT CHARACTERISTICS; FERTILIZING-CAPACITY; SPERMATOZOA; REPRODUCTION AB As part of a longitudinal study of human semen characteristics of unexposed workers, sperm motility measurements were made using computer-assisted sperm analysis. Motility analyses were conducted on monthly samples from 46 men for 9 months. Measurements of curvilinear velocity, straight-line velocity (VSL), linearity, amplitude of lateral head displacement (ALH), and beat-cross frequency were collected in eight microscope fields for each semen sample. The variability within a sample, between samples from the same individual (between monthly samples), and between individuals were calculated using a nested, analysis of variance. For all sperm motility measurements, at least 90% of the variation was observed between cells within a semen sample. For all variables, the component of variation between subjects was the smallest percentage (ranging from 1.3% for ALH to 4.0% for VSL). When sample means were used in the nested analysis of variation, at least 75% of the variation was observed between samples from the same individual. These results will be useful in power calculations for future studies. RP SCHRADER, SM (reprint author), NIOSH,DIV BIOMED & BEHAV SCI,MS C-23,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. RI Schrader, Steven/E-8120-2011 NR 16 TC 18 Z9 18 U1 0 U2 1 PU AMER SOC ANDROLOGY, INC PI LAWRENCE PA C/O ALLEN PRESS, INC PO BOX 368, LAWRENCE, KS 66044 SN 0196-3635 J9 J ANDROL JI J. Androl. PD MAR-APR PY 1991 VL 12 IS 2 BP 126 EP 131 PG 6 WC Andrology SC Endocrinology & Metabolism GA FE979 UT WOS:A1991FE97900006 PM 2050580 ER PT J AU REGNERY, RL SPRUILL, CL PLIKAYTIS, BD AF REGNERY, RL SPRUILL, CL PLIKAYTIS, BD TI GENOTYPIC IDENTIFICATION OF RICKETTSIAE AND ESTIMATION OF INTRASPECIES SEQUENCE DIVERGENCE FOR PORTIONS OF 2 RICKETTSIAL GENES SO JOURNAL OF BACTERIOLOGY LA English DT Article ID EPIDEMIC TYPHUS RICKETTSIAE; SPOTTED-FEVER GROUP; MONOCLONAL-ANTIBODIES; FLYING SQUIRRELS; CITRATE SYNTHASE; SP-NOV; DNA; STRAINS; PROWAZEKII; IMMUNOFLUORESCENCE AB DNA sequences from specific genes, amplified by the polymerase chain reaction technique, were used as substrata for nonisotopic restriction endonuclease fragment length polymorphism differentiation of rickettsial species and genotypes. The products amplified using a single pair of oligonucleotide primers (derived from a rickettsial citrate synthase gene sequence) and cleaved with restriction endonucleases were used to differentiate almost all recognized species of rickettsiae. A second set of primers was used for differentiation of all recognized species of closely related spotted fever group rickettsiae. The procedure circumvents many technical obstacles previously associated with identification of rickettsial species. Multiple amplified DNA digest patterns were used to estimate the intraspecies nucleotide sequence divergence for the genes coding for rickettsial citrate synthase and a large antigen-coding gene of the spotted fever group rickettsiae. The estimated relationships deduced from these genotypic data correlate reasonably well with established rickettsial taxonomic schemes. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,STAT SERV ACTIV,ATLANTA,GA 30333. RP REGNERY, RL (reprint author), CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,VIRAL & RICKETTSIAL ZOONOSES BRANCH,ATLANTA,GA 30333, USA. NR 46 TC 553 Z9 566 U1 1 U2 4 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0021-9193 J9 J BACTERIOL JI J. Bacteriol. PD MAR PY 1991 VL 173 IS 5 BP 1576 EP 1589 PG 14 WC Microbiology SC Microbiology GA EZ170 UT WOS:A1991EZ17000005 PM 1671856 ER PT J AU ITO, F HUNTER, EF GEORGE, RW SWISHER, BL LARSEN, SA AF ITO, F HUNTER, EF GEORGE, RW SWISHER, BL LARSEN, SA TI SPECIFIC IMMUNOFLUORESCENCE STAINING OF TREPONEMA-PALLIDUM IN SMEARS AND TISSUES SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article ID SECONDARY SYPHILIS; LYME-DISEASE AB To date, tissue sections prepared from Formalin-fixed tissues have not been successfully stained with Treponema pallidum subspecies-specific antibody in a direct fluorescent-antibody assay. While current methods stain T. pallidum, they do not distinguish T. pallidum from other spirochetes such as Borrelia burgdorferi (E. F. Hunter, P. W. Greer, B. L. Swisher, A. R. Simons, C. E. Farshy, J. A. Crawford, and K. R. Sulzer, Arch. Pathol. Lab. Med. 108:878-880, 1984). Because trypsin pretreatment of tissue sections has enhanced other immunofluorescent-antibody (IFA) applications, we compared the use of the trypsin digestion method with the current 1% ammonium hydroxide (NH4OH) method as a means to obtain specific staining of T. pallidum in tissues by both direct and indirect IFA techniques. Pretreated T. pallidum-infected tissues sections from rabbits, hamsters, and humans were quantitatively examined with the direct fluorescent-antibody-T. pallidum test conjugate absorbed with Treponema phagedenis, the Reiter treponeme. For indirect staining, a serum specimen from a patient with syphilis absorbed by affinity chromatography with T. phagedenis was used as the primary reagent, and a fluorescein isothiocyanate-labeled rabbit anti-human globulin was used as the secondary reagent. Serum specificity was established first by examining antigen smears of T. pallidum subsp. pallidum, T. pallidum subsp. pertenue, B. burgdorferi, T. phagedenis, and Treponema denticola MRB and then by examining tissues infected with these pathogens plus those infected with four Leptospira serovars. When we stained tissue using the direct IFA method that is currently a standard method for the examination of chancre smears, we found it to be unsuitable for use with tissue. Trypsin digestion did not offer an improvement over the NH4OH pretreatment method in the specific identification of T. pallidum by direct IFA. However, specific identification of T. pallidum in tissue sections was obtained by the indirect IFA technique after either trypsin or NH4OH pretreatment. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV SEXUALLY TRANSMITTED DIS LAB RES,ATLANTA,GA 30333. CTR DIS CONTROL,CTR INFECT DIS,DIV IMMUNOL ONCOL & HEMATOL DIS,ATLANTA,GA 30333. NIPPON MED COLL,HOSP 2,DEPT DERMATOL,KANAGAWA,JAPAN. NR 29 TC 11 Z9 11 U1 0 U2 1 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD MAR PY 1991 VL 29 IS 3 BP 444 EP 448 PG 5 WC Microbiology SC Microbiology GA EY463 UT WOS:A1991EY46300007 PM 1709944 ER PT J AU THACKER, WL BENSON, RF HAWES, L GIDDING, H DWYER, B MAYBERRY, WR BRENNER, DJ AF THACKER, WL BENSON, RF HAWES, L GIDDING, H DWYER, B MAYBERRY, WR BRENNER, DJ TI LEGIONELLA-FAIRFIELDENSIS SP-NOV ISOLATED FROM COOLING-TOWER WATERS IN AUSTRALIA SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article ID TRANSPLANT RECIPIENT; PNEUMOPHILA; MONOHYDROXY; DIHYDROXY AB Three Legionella-like organisms were isolated from water from the cooling towers of two Australian institutions. The strains grew on buffered charcoal-yeast extract (BCYE) agar but not on BCYE agar in the absence of L-cysteine. Gas-liquid chromatography profiles of the isolates were consistent with those for Legionella spp. They were serologically distinct from other legionellae in a slide agglutination test. DNA hybridization studies showed that the three isolates belong to a new species of Legionella, Legionella fairfieldensis (ATCC 49588). C1 FAIRFIELD HOSP,FAIRFIELD,VIC 3078,AUSTRALIA. E TENNESSEE STATE UNIV,JAMES H QUILLEN COLL MED,JOHNSON CITY,TN 37614. RP THACKER, WL (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,ATLANTA,GA 30333, USA. RI Gidding, Heather/D-4506-2011 NR 16 TC 17 Z9 18 U1 0 U2 2 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD MAR PY 1991 VL 29 IS 3 BP 475 EP 478 PG 4 WC Microbiology SC Microbiology GA EY463 UT WOS:A1991EY46300013 PM 2037664 ER PT J AU GOUVEA, V ALLEN, JR GLASS, RI FANG, ZY BREMONT, M COHEN, J MCCRAE, MA SAIF, LJ SINARACHATANANT, P CAUL, EO AF GOUVEA, V ALLEN, JR GLASS, RI FANG, ZY BREMONT, M COHEN, J MCCRAE, MA SAIF, LJ SINARACHATANANT, P CAUL, EO TI DETECTION OF GROUP-B AND GROUP-C ROTAVIRUSES BY POLYMERASE CHAIN-REACTION SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article ID ADULT DIARRHEA ROTAVIRUS; ANTIBODIES; OUTBREAK; HUMANS; CHINA; RNA AB We adapted the polymerase chain reaction (PCR) to detect the noncultivatable group B and C rotaviruses and introduced a simple and convenient technique to purify viral RNA from stool specimens. Double-stranded RNA present in stool extracts was purified by adsorption to hydrodroxyapatite and was used as the template for reverse transcription and polymerase amplification. Primer pairs specific for group B (gene 8) and group C (gene 6) rotaviruses were selected to amplify group-characteristic sizes of cDNA copies readily identifiable in ethidium bromide-stained agarose gels. These primer pairs were used separately in individual PCR assays or were pooled with a primer pair specific for group A rotavirus (gene 9) in a combined PCR assay for the simultaneous detection of all three rotavirus groups. The method was very sensitive and was used to identify both human and porcine strains of group B and C rotaviruses in stool specimens. A second PCR amplification with internal group-specific primers served to increase further the sensitivity of the test and to confirm the diagnostic results obtained in the first amplification. C1 US FDA,WASHINGTON,DC 20204. CHINESE ACAD PREVENT MED,INST VIROL,BEIJING,PEOPLES R CHINA. LAB VIROL & IMMUNOL MOLEC,F-78352 JOUY EN JOSAS,FRANCE. UNIV WARWICK,DEPT BIOL SCI,COVENTRY CV4 7AL,W MIDLANDS,ENGLAND. PUBL HLTH LAB,REG VIRUS LAB,BRISTOL BS2 8EL,ENGLAND. OHIO STATE UNIV,OHIO AGR RES & DEV CTR,WOOSTER,OH 44691. MAHIDOL UNIV,FAC SCI,DEPT MICROBIOL,BANGKOK 10700,THAILAND. RP GOUVEA, V (reprint author), CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,VIRAL GASTROENTERITIS UNIT,ATLANTA,GA 30333, USA. NR 26 TC 136 Z9 137 U1 1 U2 2 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD MAR PY 1991 VL 29 IS 3 BP 519 EP 523 PG 5 WC Microbiology SC Microbiology GA EY463 UT WOS:A1991EY46300021 PM 1645368 ER PT J AU BAKER, CN STOCKER, SA CULVER, DH THORNSBERRY, C AF BAKER, CN STOCKER, SA CULVER, DH THORNSBERRY, C TI COMPARISON OF THE E-TEST TO AGAR DILUTION, BROTH MICRODILUTION, AND AGAR DIFFUSION SUSCEPTIBILITY TESTING TECHNIQUES BY USING A SPECIAL CHALLENGE SET OF BACTERIA SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article AB The E Test (AB Biodisk, Solna, Sweden) is a new method for performing antimicrobial susceptibility tests. It consists of an impervious carrier (5- by 50-mm strip) with a predefined antimicrobic gradient which is placed on an inoculated agar plate and processed like a disk diffusion test. Resuls are generated directly as MICs from a continuous concentration gradient covering 15 twofold dilutions, and MICs are read where the edge of the inhibition zone intersects the strip. We compared the E Test with disk diffusion, broth microdilution, and agar dilution tests by using a challenge set of 195 gram-positive and gram-negative bacteria for 14 antimicrobial agents. Also, disk diffusion, broth microdilution, and agar dilution tests were compared with each other. All test method comparisons gave > 94% agreement for the category of susceptibility. The E Test category agreement with disk diffusion and broth microdilution was 95.1%, and with agar dilution it was 95.2%. The E Test results were as reliable as the results obtained by the standard antimicrobial susceptibility testing methods. C1 CTR DIS CONTROL,CTR INFECT DIS,STAT & INFORMAT SYST BRANCH,HOSP INFECT PROGRAM,ATLANTA,GA 30333. RP BAKER, CN (reprint author), CTR DIS CONTROL,CTR INFECT DIS,ANTIMICROB INVEST BRANCH,ATLANTA,GA 30333, USA. NR 11 TC 175 Z9 178 U1 2 U2 7 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD MAR PY 1991 VL 29 IS 3 BP 533 EP 538 PG 6 WC Microbiology SC Microbiology GA EY463 UT WOS:A1991EY46300023 PM 2037671 ER PT J AU GROHMANN, G GLASS, RI GOLD, J JAMES, M EDWARDS, P BORG, T STINE, SE GOLDSMITH, C MONROE, SS AF GROHMANN, G GLASS, RI GOLD, J JAMES, M EDWARDS, P BORG, T STINE, SE GOLDSMITH, C MONROE, SS TI OUTBREAK OF HUMAN CALICIVIRUS GASTROENTERITIS IN A DAY-CARE-CENTER IN SYDNEY, AUSTRALIA SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article ID NORWALK VIRUS; CHILDREN; PREVALENCE; ANTIBODIES; DIARRHEA; ANTIGEN; INFANTS AB Between January and March 1988, an outbreak of gastroenteritis occurred among children and staff at a day-care center in Sydney, New South Wales, Australia. Over an 11-week period, 53 persons had 101 episodes of gastroenteritis; some patients had 5 separate episodes. The principal etiologic agent in the outbreak, human calicivirus (HCV), was detected by electron microscopy in 32% of fecal specimens from children and staff members with symptoms but only 8% of asymptomatic individuals (P < 0.01). HCV was confirmed by both an enzyme immunoassay and solid-phase immune electron microscopy. HCV infection was a particular problem in infants, who had the highest age-specific attack rates, had the greatest symptomatic/asymptomatic infection ratio, and were most likely to have a second symptomatic episode. The mode of transmission of this virus was not identified, and extensive efforts to control the 11-week outbreak had little effect. Prolonged excretion of HCV by some symptomatic patients and high rates of asymptomatic infection may have contributed to the extended duration of the outbreak. HCV may be a common cause of gastroenteritis in children that is underrecognized because of insensitive methods of detection. C1 NEW S WALES DEPT HLTH,SYDNEY,NSW 2060,AUSTRALIA. CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,VIRAL GASTROENTERITIS UNIT,ATLANTA,GA 30333. ALBION ST CTR,SYDNEY,NSW 2010,AUSTRALIA. RP GROHMANN, G (reprint author), WESTMEAD HOSP,INST CLIN PATHOL & MED RES,DEPT INFECT DIS & MICROBIOL,VIROL UNIT,WESTMEAD,NSW 2145,AUSTRALIA. OI Monroe, Stephan/0000-0002-5424-716X NR 30 TC 31 Z9 32 U1 0 U2 2 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD MAR PY 1991 VL 29 IS 3 BP 544 EP 550 PG 7 WC Microbiology SC Microbiology GA EY463 UT WOS:A1991EY46300025 PM 1645369 ER PT J AU SIQUEIRA, MM NASCIMENTO, JP ANDERSON, LJ AF SIQUEIRA, MM NASCIMENTO, JP ANDERSON, LJ TI ANTIGENIC CHARACTERIZATION OF RESPIRATORY SYNCYTIAL VIRUS GROUP-A AND GROUP-B ISOLATES IN RIO-DE-JANEIRO, BRAZIL SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article ID SUBGROUP-B; MONOCLONAL-ANTIBODIES; G-GLYCOPROTEIN; STRAINS; HETEROGENEITY; INFECTIONS; OUTBREAKS; PROTEINS; IMMUNITY; CHILDREN AB The antigenic characteristics of 87 strains of respiratory syncytial virus isolated in Rio de Janeiro, Brazil, from 1982 to 1988 were determined with a panel of monoclonal antibodies (MAbs) in an enzyme immunoassay. Four of these MAbs immunoprecipitated the fusion protein, and five immunoprecipitated the large glycoprotein. On the basis of the patterns of reaction of these MAbs to respiratory syncytial virus isolates in an enzyme immunoassay, we were able to separate isolates into the two major groups, A and B, and also to identify four variants within group A and three within group B. Strains from groups A and B were isolated each year, and the prevalence of the two groups varied over the seven study years. C1 CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,RESP & ENTEROVIRUS BRANCH,ATLANTA,GA 30333. RP SIQUEIRA, MM (reprint author), INST OSWALDO CRUZ,DEPT VIROL,RIO DE JANEIRO,BRAZIL. NR 26 TC 21 Z9 21 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD MAR PY 1991 VL 29 IS 3 BP 557 EP 559 PG 3 WC Microbiology SC Microbiology GA EY463 UT WOS:A1991EY46300027 PM 2037672 ER PT J AU ARDUINO, MJ BLAND, LA AGUERO, SM CARSON, L RIDGEWAY, M FAVERO, MS AF ARDUINO, MJ BLAND, LA AGUERO, SM CARSON, L RIDGEWAY, M FAVERO, MS TI COMPARISON OF MICROBIOLOGIC ASSAY-METHODS FOR HEMODIALYSIS FLUIDS SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article AB To help prevent pyrogenic reactions and bacteremia in hemodialysis patients, the Association for the Advancement of Medical Instrumentation and the Centers for Disease Control recommend microbiologic assay of hemodialysis fluids at least monthly. Five commercially available assay systems were evaluated by using the membrane filtration technique with standard methods agar and trypticase soy agar as the standards for comparison. Each assay system was challenged with dialysate and reverse-osmosis water from local dialysis centers, aqueous suspensions of eight laboratory strains of gram-negative bacilli and nontuberculous mycobacteria, and a mixed microbial flora inoculated into reverse-osmosis water and laboratory-prepared dialysate. Mean viable counts from triplicate samples were obtained after incubation at 37-degrees-C for up to 72 h. The efficiency of recovery varied with the specific type of microbial challenge. The SPC water sampler (Millipore Corp., Bedford, Mass.) was the most consistent in obtaining the highest viable counts. Other commercial systems were comparable to each other in overall performance. All assay systems tested provided an acceptable balance between microbial recovery and required sampling time, equipment, and expertise. RP ARDUINO, MJ (reprint author), CTR DIS CONTROL,CTR INFECT DIS,HOSP INFECT PROGRAM,NOSOCOMIAL INFECT LAB BRANCH,ATLANTA,GA 30333, USA. RI Arduino, Matthew/C-1461-2012 OI Arduino, Matthew/0000-0001-7072-538X NR 14 TC 18 Z9 18 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD MAR PY 1991 VL 29 IS 3 BP 592 EP 594 PG 3 WC Microbiology SC Microbiology GA EY463 UT WOS:A1991EY46300034 PM 2037676 ER PT J AU RUO, SL MITCHELL, SW KILEY, MP ROUMILLAT, LF FISHERHOCH, SP MCCORMICK, JB AF RUO, SL MITCHELL, SW KILEY, MP ROUMILLAT, LF FISHERHOCH, SP MCCORMICK, JB TI ANTIGENIC RELATEDNESS BETWEEN ARENAVIRUSES DEFINED AT THE EPITOPE LEVEL BY MONOCLONAL-ANTIBODIES SO JOURNAL OF GENERAL VIROLOGY LA English DT Article ID LYMPHOCYTIC CHORIOMENINGITIS VIRUS; LASSA VIRUS; CROSS-REACTIVITY; PROTEIN-A; SEQUENCE; RNA AB Monoclonal antibodies (MAbs) were produced against two African arenaviruses, Lassa virus and Mopeia virus. Competitive binding analysis of MAbs identified four antigenic sites on the nucleoprotein (NP), two on glycoprotein 1 (GP1) and six on glycoprotein 2 (GP2) of the Josiah strain of Lassa virus. 64 virus isolates from western, central and southern Africa were all consistently distinguishable by MAbs to certain epitopic sites on GP1, GP2 and NP viral proteins. Furthermore, MAbs to Lassa virus GP1 and NP uniformly distinguished viruses from the West African countries of Sierra Leone, Liberia and Guinea from those of Nigeria. GP2-directed MAbs to two African arenaviruses reacted broadly with South American arenaviruses demonstrating that an epitopic site on GP2 may be the most highly conserved antigen in the arenavirus group. RP RUO, SL (reprint author), CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,SPECIAL PATHOGENS BRANCH,ATLANTA,GA 30333, USA. NR 29 TC 39 Z9 40 U1 0 U2 0 PU SOC GENERAL MICROBIOLOGY PI READING PA HARVEST HOUSE 62 LONDON ROAD, READING, BERKS, ENGLAND RG1 5AS SN 0022-1317 J9 J GEN VIROL JI J. Gen. Virol. PD MAR PY 1991 VL 72 BP 549 EP 555 DI 10.1099/0022-1317-72-3-549 PN 3 PG 7 WC Biotechnology & Applied Microbiology; Virology SC Biotechnology & Applied Microbiology; Virology GA FB091 UT WOS:A1991FB09100011 PM 1706408 ER PT J AU FULTZ, PN SIEGEL, RL BRODIE, A MAWLE, AC STRICKER, RB SWENSON, RB ANDERSON, DC MCCLURE, HM AF FULTZ, PN SIEGEL, RL BRODIE, A MAWLE, AC STRICKER, RB SWENSON, RB ANDERSON, DC MCCLURE, HM TI PROLONGED CD4+ LYMPHOCYTOPENIA AND THROMBOCYTOPENIA IN A CHIMPANZEE PERSISTENTLY INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID HIV-1 SEROPOSITIVE INDIVIDUALS; T-LYMPHOTROPIC RETROVIRUS; AIDS; MODEL; CELLS; TRANSMISSION; PLASMA; STRAIN AB The immunologic and virologic status of a chimpanzee inoculated with multiple isolates of the human immunodeficiency virus type 1 (HIV-1) were assessed over 57 months to determine whether prolonged thrombocytopenia and CD4+ lymphocytopenia observed in the animal might be associated with long-term HIV infection. Although the chimpanzee showed no signs of disease, it lost both CD4+ (as low as 134 cells/mu-l) and CD8+ lymphocytes approximately 30 months after initial infection, followed by thrombocytopenia that has persisted for > 2 years. Lymphopenia and thrombocytopenia were preceded by or coincided with the appearance of antibodies cross-reactive with histone H2B and decreased levels of complement component C4; an eightfold decrease in HIV-specific antibody titers; the inability of CD8+ lymphocytes to suppress virus replication; impaired proliferative responses to T cell mitogens; and the isolation of cell-free HIV from plasma. These data suggest that, given sufficient time, HIV-infected chimpanzees may develop disease. C1 EMORY UNIV,YERKES REG PRIMATE RES CTR,ATLANTA,GA 30322. EMORY UNIV,DEPT PATHOL,ATLANTA,GA 30322. CTR DIS CONTROL,CTR INFECT DIS,DIV HOST FACTORS,ATLANTA,GA 30333. SAN FRANCISCO CHILDRENS HOSP,SAN FRANCISCO,CA. FU NCRR NIH HHS [RR-00165]; PHS HHS [200-88-0607] NR 27 TC 35 Z9 35 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD MAR PY 1991 VL 163 IS 3 BP 441 EP 447 PG 7 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EY495 UT WOS:A1991EY49500002 PM 1671679 ER PT J AU HADLER, SC JUDSON, FN OMALLEY, PM ALTMAN, NL PENLEY, K BUCHBINDER, S SCHABLE, CA COLEMAN, PJ OSTROW, DN FRANCIS, DP AF HADLER, SC JUDSON, FN OMALLEY, PM ALTMAN, NL PENLEY, K BUCHBINDER, S SCHABLE, CA COLEMAN, PJ OSTROW, DN FRANCIS, DP TI OUTCOME OF HEPATITIS-B VIRUS-INFECTION IN HOMOSEXUAL MEN AND ITS RELATION TO PRIOR HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID SURFACE-ANTIGEN; VACCINE; PREVENTION; EFFICACY; HIV; ANTIBODY; TRIAL; IMMUNOGENICITY; MECHANISMS; PLASMA AB To investigate the effect of human immunodeficiency virus type 1 (HIV-1) infection on subsequent hepatitis B virus (HBV) infection, HIV antibody was sought in homosexual men who developed HBV infection during a hepatitis B vaccine trial. Among 134 unvaccinated HIV-1-negative men, 7% became HBV carriers, 64% had viremia, and 42% had clinical illness. Among vaccinated HIV-1-negative men, HBV infection severity decreased with number of vaccine doses administered. When adjusted for prior hepatitis B vaccination status, persons with HIV-1 infection preceding HBV infection had a significantly higher risk of developing HBV carriage, viremia, prolonged ALT elevation, and clinical illness. Among HIV-1-infected men, the risk of HBV carriage was increased in unvaccinated persons (21%) and those who failed to respond to vaccination (31%) and further increased in those who received vaccine doses at the time they developed new HBV infection (56%-80%), suggesting inactivated hepatitis B vaccine may temporarily impair the immune response to HBV infection in HIV-1-infected persons. HIV-1 infection was also associated with reduced alanine aminotransferase elevations during the first 36 months of follow-up of men who became HBV carriers. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,HEPATITIS BRANCH,ATLANTA,GA 30333. CTR DIS CONTROL,DIV HIV AIDS,ATLANTA,GA 30333. DENVER DIS CONTROL,DENVER,CO. SAN FRANCISCO DEPT HLTH,SAN FRANCISCO,CA. CALIF DEPT HLTH SERV,BERKELEY,CA 94704. HOWARD BROWN MEM CLIN,CHICAGO,IL. UNIV MICHIGAN,MIDWEST AIDS BEHAV RES CTR,ANN ARBOR,MI 48109. NR 28 TC 175 Z9 178 U1 0 U2 1 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD MAR PY 1991 VL 163 IS 3 BP 454 EP 459 PG 6 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EY495 UT WOS:A1991EY49500004 PM 1825315 ER PT J AU DAWSON, JE RIKIHISA, Y EWING, SA FISHBEIN, DB AF DAWSON, JE RIKIHISA, Y EWING, SA FISHBEIN, DB TI SEROLOGIC DIAGNOSIS OF HUMAN EHRLICHIOSIS USING 2 EHRLICHIA-CANIS ISOLATES SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID IN-VITRO CULTIVATION; ACTIVE SURVEILLANCE; CAUSATIVE AGENT; HUMAN INFECTION; PANCYTOPENIA; FEVER AB Ehrlichia canis or a closely related rickettsial organism has been implicated serologically and morphologically as the causative agent of human ehrlichiosis in the United States. Although E. canis has been serially propagated in primary canine monocytes, only a limited quantity of antigen is obtained by this method. A continuous canine macrophage cell line, DH82, supports the growth of a new isolate of E. canis established from the whole blood of a carrier dog in Oklahoma. Serologic comparison of the Oklahoma isolate in the continuous canine cell line with a Florida isolate in commercial antigen slides revealed 100% specificity and 87.5% sensitivity. C1 OHIO STATE UNIV,DEPT VET PATHOBIOL,COLUMBUS,OH 43210. OKLAHOMA STATE UNIV,DEPT VET PARASITOL MICROBIOL & PUBL HLTH,STILLWATER,OK 74078. RP DAWSON, JE (reprint author), CTR DIS CONTROL,CTR INFECT DIS,VIRAL & RICKETTSIAL ZOONOSES BRANCH,DIV VIRAL & RICKETTSIAL DIS,ATLANTA,GA 30333, USA. NR 18 TC 85 Z9 87 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD MAR PY 1991 VL 163 IS 3 BP 564 EP 567 PG 4 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EY495 UT WOS:A1991EY49500021 PM 1995730 ER PT J AU WALLACE, RJ BROWN, BA SILCOX, VA TSUKAMURA, M NASH, DR STEELE, LC STEINGRUBE, VA SMITH, J SUMTER, G ZHANG, Y BLACKLOCK, Z AF WALLACE, RJ BROWN, BA SILCOX, VA TSUKAMURA, M NASH, DR STEELE, LC STEINGRUBE, VA SMITH, J SUMTER, G ZHANG, Y BLACKLOCK, Z TI CLINICAL-DISEASE, DRUG SUSCEPTIBILITY, AND BIOCHEMICAL PATTERNS OF THE UNNAMED 3RD BIOVARIANT COMPLEX OF MYCOBACTERIUM-FORTUITUM SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID RAPIDLY GROWING MYCOBACTERIA; COOPERATIVE NUMERICAL-ANALYSIS; BETA-LACTAMASES; RESISTANCE; INFECTIONS; CHELONEI; IDENTIFICATION; RANAE; ACID AB Previous studies of Mycobacterium fortuitum identified isolates that did not fit its two recognized biovariants. Eighty-five clinical isolates of this group, the "third biovariant complex," were evaluated. They represented 16% of 410 isolates of M. fortuitum submitted to a Texas laboratory and 22% of 45 isolates in Queensland, Australia. Most infections (76%) involved skin, soft tissue, or bone and occurred after metal puncture wounds or open fractures. Isolates differed from biovar fortuitum in resistance to pipemidic acid and use of mannitol and inositol as carbon sources. Two subgroups were present, and examples were deposited in the American Type Culture Collection. Isolates were resistant to doxycycline and one-third were resistant to cefoxitin. All were susceptible to amikacin, ciprofloxacin, sulfamethoxazole, and imipenem. Surgical debridement combined with drug therapy based on in vitro susceptibilities resulted in cures of cutaneous disease or osteomyelitis. DNA homology studies are needed to determine the taxonomic status of these organisms. C1 NATL CHUBU HOSP,OBU,AICHI,JAPAN. STATE HLTH LAB SERV,BRISBANE,AUSTRALIA. CTR DIS CONTROL,CTR INFECT DIS,MYCOBACTERIOL LAB,ATLANTA,GA 30333. RP WALLACE, RJ (reprint author), UNIV TEXAS,CTR HLTH,DEPT MICROBIOL,POB 2003,TYLER,TX 75710, USA. NR 22 TC 58 Z9 58 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD MAR PY 1991 VL 163 IS 3 BP 598 EP 603 PG 6 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EY495 UT WOS:A1991EY49500027 PM 1995732 ER PT J AU JORGENSEN, JH HOWELL, AW MAHER, LA FACKLAM, RR AF JORGENSEN, JH HOWELL, AW MAHER, LA FACKLAM, RR TI SEROTYPES OF RESPIRATORY ISOLATES OF STREPTOCOCCUS-PNEUMONIAE COMPARED WITH THE CAPSULAR TYPES INCLUDED IN THE CURRENT PNEUMOCOCCAL VACCINE SO JOURNAL OF INFECTIOUS DISEASES LA English DT Note ID UNITED-STATES; EFFICACY AB The serotypes of 474 clinically significant Streptococcus pneumoniae respiratory isolates collected during a national surveillance study in 1987-1988 were compared to the capsular types included in the 23-valent pneumococcal polysaccharide vaccine licensed for use in the United States. Overall, 355 isolates (74.9%) belonged to types included in the current vaccine, while another 65 (13.7%) were types serologically related to vaccine types and likely to be protective by virtue of cross-reactivity. Relatively few isolates (9.1%) belonged to nonvaccine serotypes, and only 2.3% were nontypable. The mucoid serotype 3 was most frequent (13.1% of total), followed by 19F (9.3%), 23F (7.4%), 6B and 14 (5.7% each), and 4 and 6A (5.5% each). The most frequent type not included in the vaccine was type 16 (2.1% of all isolates). Thus, nearly 89% of respiratory isolates included in this study were encompassed within the antigenic spectrum of the currently marketed pneumococcal vaccine. C1 CTR DIS CONTROL,RESP BACTERIAL REFERENCE LAB,ATLANTA,GA 30333. RP JORGENSEN, JH (reprint author), UNIV TEXAS,HLTH SCI CTR,DEPT PATHOL,7703 FLOYD CURL DR,SAN ANTONIO,TX 78284, USA. NR 17 TC 27 Z9 28 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD MAR PY 1991 VL 163 IS 3 BP 644 EP 646 PG 3 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EY495 UT WOS:A1991EY49500038 PM 1995737 ER PT J AU LEE, LA TAYLOR, J CARTER, GP QUINN, B FARMER, JJ TAUXE, RV AF LEE, LA TAYLOR, J CARTER, GP QUINN, B FARMER, JJ TAUXE, RV TI YERSINIA-ENTEROCOLITICA O-3 - AN EMERGING CAUSE OF PEDIATRIC GASTROENTERITIS IN THE UNITED-STATES SO JOURNAL OF INFECTIOUS DISEASES LA English DT Note AB After an outbreak of Yersinia enterocolitica infections among black children in Atlanta, a seven-hospital study was conducted to determine the importance of this pathogen in other communities with large black populations. Of 4841 stool specimens from patients with gastroenteritis examined between November 1989 and January 1990, Y. enterocolitica, Shigella, Campylobacter, and Salmonella were identified in 38, 49, 60, and 98 specimens, respectively; 34 (92%) of 37 Y. enterocolitica isolates were serotype O:3. Of the 38 patients with yersiniosis, 37 (97%) were children. Illnesses were clustered around the holidays, and 20 (62%) of 32 patients had been exposed to raw pork intestines in the 2 weeks before onset. Exposure was significantly associated with illness in a case-control study of eight patients identified at one hospital (P = .004). Infants less-than-or-equal-to 6 months old with yersiniosis were more likely to have immature-to-total neutrophil ratios > 0.50 than were infants of comparable age with salmonellosis (P = .02). Infrequently isolated in the past, Y. enterocolitica O:3 is emerging as an important enteric pathogen in this country, particularly among black children. C1 JOHNS HOPKINS UNIV HOSP,DEPT LAB MED,BALTIMORE,MD 21205. MARYLAND DEPT HLTH & MENTAL HYG,BALTIMORE,MD 21201. RP LEE, LA (reprint author), CTR DIS CONTROL,ENTER DIS BRANCH,MAILSTOP C09,ATLANTA,GA 30333, USA. NR 14 TC 72 Z9 75 U1 0 U2 3 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD MAR PY 1991 VL 163 IS 3 BP 660 EP 663 PG 4 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EY495 UT WOS:A1991EY49500043 PM 1995741 ER PT J AU MASTRO, TD FIELDS, BS BREIMAN, RF CAMPBELL, J PLIKAYTIS, BD SPIKA, JS AF MASTRO, TD FIELDS, BS BREIMAN, RF CAMPBELL, J PLIKAYTIS, BD SPIKA, JS TI NOSOCOMIAL LEGIONNAIRES-DISEASE AND USE OF MEDICATION NEBULIZERS SO JOURNAL OF INFECTIOUS DISEASES LA English DT Note ID LEGIONELLA-PNEUMOPHILA; CONTAMINATION; CHLORINE; WATER AB Guidelines for the prevention of nosocomial pneumonia specify that only sterile fluids should be used for aerosol therapy; however, this recommendation may not be uniformly followed. Thirteen patients with nosocomial pneumonia due to Legionella pneumophila serogroup 3 (Lp3) were identified at a community hospital in the period from 1984 through 1988; 12 patients (92%) had chronic obstructive pulmonary disease; and 9 patients (69%) died. An epidemiologic investigation suggested that the use of nebulizers to deliver medication was associated with acquiring legionnaires' disease. The hospital potable water system was contaminated with Lp3, and a survey indicated that tap water was commonly used to wash medication nebulizers. Lp3 in respirable-size droplets was isolated from aerosols generated by a nebulizer containing Lp3 at one-tenth the concentration found in the hospital potable water. These findings support the recommendation that only sterile fluids be used for filling or cleaning respiratory care equipment and suggest that this guideline is not universally followed. C1 WASHINGTON STATE DEPT SOCIAL & HLTH SERV,SEATTLE,WA. RP MASTRO, TD (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,RESP DIS BRANCH,MAILSTOP C-09,ATLANTA,GA 30333, USA. NR 15 TC 74 Z9 79 U1 0 U2 1 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD MAR PY 1991 VL 163 IS 3 BP 667 EP 671 PG 5 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EY495 UT WOS:A1991EY49500045 PM 1995743 ER PT J AU MONROE, SS GLASS, RI NOAH, N FLEWETT, TH CAUL, EO ASHTON, CI CURRY, A FIELD, AM MADELEY, R PEAD, PJ AF MONROE, SS GLASS, RI NOAH, N FLEWETT, TH CAUL, EO ASHTON, CI CURRY, A FIELD, AM MADELEY, R PEAD, PJ TI ELECTRON-MICROSCOPIC REPORTING OF GASTROINTESTINAL VIRUSES IN THE UNITED-KINGDOM, 1985-1987 SO JOURNAL OF MEDICAL VIROLOGY LA English DT Article DE ASTROVIRUS; CALICIVIRUS; CLASSIFICATION ID ANTIBODY AB We examined some epidemiological features of the viruses associated with gastrointestinal illness, using national data reported by electron microscopists in the United Kingdom. During the 3 years analyzed (1985-1987), a total of 1,993 positive detections of astroviruses, caliciviruses, coronaviruses, and small round structured viruses (SRSVs) were reported. In 1 year of this period, 8,210 rotaviruses were reported. More than 90% of the astroviruses and caliciviruses were detected in children under 5 years of age, while coronaviruses and SRSVs were detected in adults as well as children. Detections of astroviruses increased in the winter and were infrequent during the summer, a seasonal pattern similar to that observed for rotaviruses. There was some variability between reporting regions in rates of detection of fecal viruses. We have attempted to identify the reasons for this. We make suggestions for improving the detection of human fecal viruses, and we recognize the need for continued surveillance of these agents. C1 PUBL HLTH LAB SERV,CTR COMMUNICABLE DIS SURVEILLANCE,LONDON,ENGLAND. E BIRMINGHAM DIST GEN HOSP,REG VIRUS LAB,BIRMINGHAM B9 5ST,W MIDLANDS,ENGLAND. PUBL HLTH LAB,JOINT REG VIRUS LAB,BRISTOL,ENGLAND. FAZAKERLEY DIST GEN HOSP,PUBL HLTH LAB,LIVERPOOL,ENGLAND. WITHINGTON HOSP,PUBL HLTH LAB,MANCHESTER M20 8LR,LANCS,ENGLAND. CENT PUBL HLTH LAB,VIRUS REFERENCE LAB,LONDON NW9 5HT,ENGLAND. ROYAL VICTORIA INFIRM,DEPT VIROL,NEWCASTLE TYNE NE1 4LP,TYNE & WEAR,ENGLAND. ST MARYS GEN HOSP,PUBL HLTH LAB,PORTSMOUTH PO3 6AQ,HANTS,ENGLAND. RP MONROE, SS (reprint author), CTR DIS CONTROL,CTR INFECT DIS,ATLANTA,GA 30333, USA. OI Monroe, Stephan/0000-0002-5424-716X NR 10 TC 43 Z9 43 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0146-6615 J9 J MED VIROL JI J. Med. Virol. PD MAR PY 1991 VL 33 IS 3 BP 193 EP 198 DI 10.1002/jmv.1890330310 PG 6 WC Virology SC Virology GA FC694 UT WOS:A1991FC69400009 PM 1652619 ER PT J AU JANSSEN, RS SCHONBERGER, LB AF JANSSEN, RS SCHONBERGER, LB TI CREUTZFELDT-JAKOB DISEASE FROM ALLOGENEIC DURA - A REVIEW OF RISKS AND SAFETY - DISCUSSION SO JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY LA English DT Discussion ID MATER; GRAFT RP JANSSEN, RS (reprint author), CTR DIS CONTROL,CTR INFECT DIS,ATLANTA,GA 30333, USA. NR 11 TC 16 Z9 17 U1 0 U2 0 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0278-2391 J9 J ORAL MAXIL SURG JI J. Oral Maxillofac. Surg. PD MAR PY 1991 VL 49 IS 3 BP 274 EP 275 DI 10.1016/0278-2391(91)90219-C PG 2 WC Dentistry, Oral Surgery & Medicine SC Dentistry, Oral Surgery & Medicine GA EZ535 UT WOS:A1991EZ53500012 ER PT J AU ROGERS, MF OU, CY KILBOURNE, B SCHOCHETMAN, G AF ROGERS, MF OU, CY KILBOURNE, B SCHOCHETMAN, G TI EARLY IDENTIFICATION OF HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION IN INFANTS SO JOURNAL OF PEDIATRICS LA English DT Letter RP ROGERS, MF (reprint author), CTR DIS CONTROL, ATLANTA, GA 30333 USA. NR 3 TC 0 Z9 0 U1 0 U2 0 PU MOSBY-ELSEVIER PI NEW YORK PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA SN 0022-3476 EI 1097-6833 J9 J PEDIATR-US JI J. Pediatr. PD MAR PY 1991 VL 118 IS 3 BP 490 EP 491 DI 10.1016/S0022-3476(05)82177-8 PG 2 WC Pediatrics SC Pediatrics GA FB292 UT WOS:A1991FB29200035 PM 1999798 ER PT J AU GOODMAN, RA ISTRE, GR JORDAN, FB HERNDON, JL KELAGHAN, J AF GOODMAN, RA ISTRE, GR JORDAN, FB HERNDON, JL KELAGHAN, J TI ALCOHOL AND FATAL INJURIES IN OKLAHOMA SO JOURNAL OF STUDIES ON ALCOHOL LA English DT Article ID HOMICIDE VICTIMS AB To assess the usefulness of medical examiner data in describing the relationship between alcohol use and fatal injuries, 1978-84 data from the Office of the Chief Medical Examiner (ME), State of Oklahoma, was examined. In each year in the study period, approximately 1,500 deaths resulted from unintentional injuries (UI) and 800 deaths resulted from intentional injuries (i.e., suicides and homicides). For persons who died on the same day they were injured, testing for blood alcohol ranged from 90% of homicide victims, to 73% of suicide victims and to 66% of UI victims. Alcohol was associated with 52% of homicides, 49% of UI and 40% of suicides. Alcohol was detected most often in samples from Hispanic men and from Native Americans of both sexes. This study suggests that state public health agencies and researchers should consider the use of ME data for epidemiologic information on the relationship between alcohol and injury-related mortality and for surveillance of these problems. RP GOODMAN, RA (reprint author), CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 11 TC 31 Z9 32 U1 0 U2 0 PU ALCOHOL RES DOCUMENTATION INC CENT ALCOHOL STUD RUTGERS UNIV PI PISCATAWAY PA PO BOX 969, PISCATAWAY, NJ 08855-0969 SN 0096-882X J9 J STUD ALCOHOL JI J. Stud. Alcohol PD MAR PY 1991 VL 52 IS 2 BP 156 EP 161 PG 6 WC Substance Abuse; Psychology SC Substance Abuse; Psychology GA EY615 UT WOS:A1991EY61500008 PM 2016876 ER PT J AU ROTHENBERG, R LENTZNER, HR PARKER, RA AF ROTHENBERG, R LENTZNER, HR PARKER, RA TI POPULATION AGING PATTERNS - THE EXPANSION OF MORTALITY SO JOURNALS OF GERONTOLOGY LA English DT Article ID COMPRESSION; DEATH; MORBIDITY AB We used the hypothesis of mortality compression as a framework to examine patterns of mortality from 1962 to 1984. Data from national vital statistics records were used for analysis of the changing age at death for percentiles of the population. Data from the Social Security Administration and the U.S. Census Bureau were used to calculate the force of mortality. The mean age at death for all percentiles, including the oldest groups, has risen during the interval. Examination of the coefficient of variation for the mean age at death suggests that there is a relative increase in the variability of age at death among the oldest old. The available data do not fit a hypothetical sequence of normal density distributions with an increasing mean and declining standard deviation. The force of mortality in those over 85 years appears to be decreasing in a pattern similar to that for those under 85 years. Current mortality patterns suggest an "expansion," rather than compression, of mortality at the oldest ages. Further refinement of these observations, with improved data on mortality among the oldest old, will be helpful in delineating mortality patterns. C1 VANDERBILT UNIV,MED CTR,SCH MED,DEPT PREVENT MED,NASHVILLE,TN 37232. RP ROTHENBERG, R (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,1600 CLIFTON RD NE,ATLANTA,GA 30333, USA. NR 15 TC 23 Z9 23 U1 1 U2 3 PU GERONTOLOGICAL SOCIETY AMER PI WASHINGTON PA 1275 K STREET NW SUITE 350, WASHINGTON, DC 20005-4006 SN 0022-1422 J9 J GERONTOL JI J. Gerontol. PD MAR PY 1991 VL 46 IS 2 BP S66 EP S70 PG 5 WC Geriatrics & Gerontology; Gerontology SC Geriatrics & Gerontology GA GQ139 UT WOS:A1991GQ13900021 PM 1997584 ER PT J AU ORENSTEIN, WA PLOTKIN, S AF ORENSTEIN, WA PLOTKIN, S TI PROVIDING MMR VACCINE TO CHILDREN SO MINNESOTA MEDICINE LA English DT Letter RP ORENSTEIN, WA (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,DIV IMMUNIZAT,ATLANTA,GA 30333, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MINN MED ASSN PI MINNEAPOLIS PA SUITE 400 2221 UNIV AVE S E, MINNEAPOLIS, MN 55414 SN 0026-556X J9 MINN MED PD MAR PY 1991 VL 74 IS 3 BP 7 EP 8 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA FB447 UT WOS:A1991FB44700003 PM 2030684 ER PT J AU LEE, NC RUBIN, GL GRIMES, DA AF LEE, NC RUBIN, GL GRIMES, DA TI MEASURES OF SEXUAL-BEHAVIOR AND THE RISK OF PELVIC INFLAMMATORY DISEASE SO OBSTETRICS AND GYNECOLOGY LA English DT Article ID INTRAUTERINE-DEVICE; SALPINGITIS; CONTRACEPTIVES; EPIDEMIOLOGY; ASSOCIATION; SPERMATOZOA; FREQUENCY; TRENDS AB A woman's sexual behavior affects her risk of acquiring pelvic inflammatory disease, but the risks have not been well characterized. To study the association between pelvic inflammatory disease and sexual behavior, we analyzed data from a multicenter, case-control study involving 712 women hospitalized with an initial episode of pelvic inflammatory disease and 2719 hospitalized control women without a history of pelvic inflammatory disease. Study participants provided information on their frequency of intercourse, number of recent sexual partners, and previous history of gonorrhea. Logistic regression methods were used to adjust for confounding factors. Women who reported having four or more sexual partners were over three times more likely to be hospitalized for pelvic inflammatory disease (relative risk 3.4; 95% confidence interval 2.2-5.3) than were women who reported only one recent sexual partner. To a lesser extent, frequent sexual intercourse and history of gonorrhea also increased a woman's risk of pelvic inflammatory disease. Frequent intercourse was a strong risk factor for pelvic inflammatory disease among a subgroup of women who were at low risk for acquiring a sexually transmitted disease: Married women with one recent sexual partner with intercourse six or more times per week had a risk of pelvic inflammatory disease of 3.2 (1.4-7.2) compared with similar women having intercourse less than once per week. Frequent intercourse, which does not by itself increase the risk of acquiring a sexually transmitted disease, may increase a woman's risk of pelvic inflammatory disease. C1 DEPT HLTH EPIDEMIOL & HLTH SERV EVALUAT BRANCH,SYDNEY,NSW,AUSTRALIA. UNIV SO CALIF,SCH MED,DEPT OBSTET & GYNECOL,LOS ANGELES,CA 90033. RP LEE, NC (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV REPROD HLTH C06,ATLANTA,GA 30333, USA. NR 24 TC 24 Z9 24 U1 0 U2 1 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0029-7844 J9 OBSTET GYNECOL JI Obstet. Gynecol. PD MAR PY 1991 VL 77 IS 3 BP 425 EP 430 PG 6 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA EZ380 UT WOS:A1991EZ38000020 PM 1992411 ER PT J AU DAWSON, CD SCHEPPLER, JA NICHOLSON, JKA HOLMAN, RC AF DAWSON, CD SCHEPPLER, JA NICHOLSON, JKA HOLMAN, RC TI ENUMERATION OF ANTIGEN SITES ON CELLS BY FLOW-CYTOMETRY SO PATHOBIOLOGY LA English DT Article DE MONOCLONAL ANTIBODIES; LYMPHOCYTES; ANTIGEN DENSITY; MICROBEADS ID T-CELL; MONOCLONAL-ANTIBODY; MODULATION; SURFACE; EXPRESSION; VIRUS AB We evaluated a cytofluorometric method for determining the number of antigens expressed on the cell surface of human lymphocytes. Using beads that have a known number of binding sites for mouse immunoglobulin and monoclonal antibodies specific for various antigens on human lymphocytes, we found that this system is quite reproducible, reliable and technically easy to perform. The greatest source of variation in expression of cell surface antigens is interdonor variability. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV HOST FACTORS,STAT & DATA MANAGEMENT ACTIV,ATLANTA,GA 30333. RP DAWSON, CD (reprint author), CTR DIS CONTROL,CTR INFECT DIS,IMMUNOL BRANCH,1-1202 A25,ATLANTA,GA 30333, USA. NR 14 TC 32 Z9 32 U1 0 U2 0 PU KARGER PI BASEL PA ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND SN 1015-2008 J9 PATHOBIOLOGY JI Pathobiology PD MAR-APR PY 1991 VL 59 IS 2 BP 57 EP 61 DI 10.1159/000163617 PG 5 WC Cell Biology; Pathology SC Cell Biology; Pathology GA FE055 UT WOS:A1991FE05500001 PM 1863352 ER PT J AU SCHUCHAT, A LIZANO, C BROOME, CV SWAMINATHAN, B KIM, CM WINN, K AF SCHUCHAT, A LIZANO, C BROOME, CV SWAMINATHAN, B KIM, CM WINN, K TI OUTBREAK OF NEONATAL LISTERIOSIS ASSOCIATED WITH MINERAL-OIL SO PEDIATRIC INFECTIOUS DISEASE JOURNAL LA English DT Article DE LISTERIA-MONOCYTOGENES; LISTERIOSIS; NEONATAL INFECTION; NOSOCOMIAL INFECTION; LIPOID PNEUMONIA; MINERAL OIL; POLYMERASE CHAIN REACTION ID MULTILOCUS ENZYME ELECTROPHORESIS; EPIDEMIC LISTERIOSIS; CROSS-INFECTION; MONOCYTOGENES; TRANSMISSION; MENINGITIS AB In June, 1989, an outbreak of nosocomial listeriosis occurred in Costa Rica. Listeria monocytogenes was isolated from 9 ill infants 4 to 8 days old who were born after the delivery of an infant with early onset listeriosis. One nosocomial infection was fatal, 2 required mechanical ventilation and 1 resulted in hemiparesis. A higher proportion of cases than other infants born during the outbreak were delivered by cesarean section (55% vs. 24%, P = 0.04). Compared with the mothers of 36 random controls, case mothers were more often primiparous (odds ratio, 6.2, P = 0.03) or received general anesthesia before delivery (odds ratio, 4.4, P = 0.09). All infants were bathed with mineral oil from a multidose container. Culture of the oil by cold enrichment grew L. monocytogenes 4b with the same electrophoretic enzyme type as the outbreak strain. We hypothesize that aspiration of contaminated oil may have resulted in systemic listeriosis. General anesthesia may have increased the risk of aspiration. Lung tissue from the infant who died showed lipid-laden macrophages consistent with oil aspiration and had evidence of L. monocytogenes DNA detected by polymerase chain reaction. This is the first nosocomial outbreak of listeriosis in which a common source suggested epidemiologically was microbiologically confirmed. The high attack rate (> 200 times the United States rate of perinatal listeriosis) emphasizes the susceptibility of healthy neonates to L. monocytogenes. The results of our study led to the discontinuation of the use of mineral oil for bathing neonates in Costa Rica. C1 HENRIETTA EGLESTON HOSP,DEPT PATHOL,ATLANTA,GA. HOSP NACL NINOS DR CARLOS SAENZ HERRERA,SAN JOSE,COSTA RICA. RP SCHUCHAT, A (reprint author), CTR DIS CONTROL,MENINGITIS & SPECIAL PATHOGENS BRANCH,ATLANTA,GA 30333, USA. NR 30 TC 31 Z9 32 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0891-3668 J9 PEDIATR INFECT DIS J JI Pediatr. Infect. Dis. J. PD MAR PY 1991 VL 10 IS 3 BP 183 EP 189 DI 10.1097/00006454-199103000-00003 PG 7 WC Immunology; Infectious Diseases; Pediatrics SC Immunology; Infectious Diseases; Pediatrics GA FC019 UT WOS:A1991FC01900003 PM 2041663 ER PT J AU DEQUADROS, CA ANDRUS, JK OLIVE, JM DASILVEIRA, CM EIKHOF, RM CARRASCO, P FITZSIMMONS, JW PINHEIRO, FP AF DEQUADROS, CA ANDRUS, JK OLIVE, JM DASILVEIRA, CM EIKHOF, RM CARRASCO, P FITZSIMMONS, JW PINHEIRO, FP TI ERADICATION OF POLIOMYELITIS - PROGRESS IN THE AMERICA SO PEDIATRIC INFECTIOUS DISEASE JOURNAL LA English DT Article DE POLIOMYELITIS; ERADICATION; IMMUNIZATION; PAN-AMERICAN-HEALTH-ORGANIZATION ID VACCINE C1 CTR DIS CONTROL,DIV IMMUNIZAT,ATLANTA,GA 30333. RP DEQUADROS, CA (reprint author), PAN AMER HLTH ORG,EXPANDED PROGRAM IMMUNIZAT,525 23RD ST NW,WASHINGTON,DC 20037, USA. NR 37 TC 98 Z9 98 U1 0 U2 1 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0891-3668 J9 PEDIATR INFECT DIS J JI Pediatr. Infect. Dis. J. PD MAR PY 1991 VL 10 IS 3 BP 222 EP 229 DI 10.1097/00006454-199103000-00011 PG 8 WC Immunology; Infectious Diseases; Pediatrics SC Immunology; Infectious Diseases; Pediatrics GA FC019 UT WOS:A1991FC01900011 PM 2041671 ER PT J AU NAVARRETE, S STETLER, HC AVILA, C ARANDA, JAG SANTOSPRECIADO, JI AF NAVARRETE, S STETLER, HC AVILA, C ARANDA, JAG SANTOSPRECIADO, JI TI AN OUTBREAK OF CRYPTOSPORIDIUM DIARRHEA IN A PEDIATRIC HOSPITAL SO PEDIATRIC INFECTIOUS DISEASE JOURNAL LA English DT Note DE CRYPTOSPORIDIUM; NOSOCOMIAL TRANSMISSION; PEDIATRIC; AIDS ID ANIMALS C1 SECRETARIAT HLTH,DIRECTORATE EPIDEMIOL,RESIDENCY PROGRAM APPL EPIDEMIOL,MEXICO CITY,MEXICO. CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,MEXICAN RESIDENCY PROGRAM APPL EPIDEMIOL,ATLANTA,GA 30333. RP NAVARRETE, S (reprint author), SECRETARIAT HLTH,HOSP INFANTIL MEXICO,DEPT ENFERMEDADES INFECCIOSAS & PARASITARIAS,MEXICO CITY 06720,DF,MEXICO. NR 13 TC 24 Z9 24 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0891-3668 J9 PEDIATR INFECT DIS J JI Pediatr. Infect. Dis. J. PD MAR PY 1991 VL 10 IS 3 BP 248 EP 250 DI 10.1097/00006454-199103000-00016 PG 3 WC Immunology; Infectious Diseases; Pediatrics SC Immunology; Infectious Diseases; Pediatrics GA FC019 UT WOS:A1991FC01900016 PM 2041674 ER PT J AU MACGOWAN, RJ MACGOWAN, CA SERDULA, MK LANE, JM JOESOEF, RM COOK, FH AF MACGOWAN, RJ MACGOWAN, CA SERDULA, MK LANE, JM JOESOEF, RM COOK, FH TI BREAST-FEEDING AMONG WOMEN ATTENDING WOMEN, INFANTS, AND CHILDREN CLINICS IN GEORGIA, 1987 SO PEDIATRICS LA English DT Article DE BREAST-FEEDING; WOMEN; INFANTS; AND CHILDREN PROGRAM ID UNITED-STATES; PATTERNS; DURATION; HEALTH AB Breast-feeding is an important determinant of the health and nutritional status of children, particularly in lower socioeconomic populations. A major goal of the Georgia Special Supplemental Food Program for Women, Infants, and Children (WIC) is to increase the practice of breast-feeding among the women it serves. Breast-feeding practices were determined among a random sample of 404 women from a cohort of 2010 who attended WIC prenatal clinics in Georgia in 1986 and were expected to deliver in February 1987. Respondents were interviewed 6 months postpartum. Of these women, 24% initially breast-fed, but only 6% continued for 6 months or longer. The initiation of breast-feeding was associated with greater maternal education and with being married. The adjusted odds of breast-feeding for mothers who were married or living as married were 3.0 (95% confidence interval, 1.7 to 5.3) times greater than for mothers who were not married or living as married. Mothers with more than 12 years, 12 years, or 10 to 11 years of education were 5.2 (1.8 to 15.3), 2.7 (1.0 to 6.9), and 2.5 (0.9 to 6.9) times more likely, respectively, to breast-feed than mothers with 9 or fewer years of education. After adjustment was made for marital status and education, the remaining variables (ethnicity, parity, age, and employment status) did not influence the initiation of breast-feeding in this low-income population. The need for vigorous promotion of breast-feeding by the Georgia WIC program is emphasized by the low rate of initiation and short duration of breast-feeding in this low-income population. C1 EMORY UNIV,DIV PUBL HLTH,ATLANTA,GA 30322. GEORGIA DEPT HUMAN RESOURCES,OFF NUTR,ATLANTA,GA. CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV NUTR,ATLANTA,GA 30333. RP MACGOWAN, RJ (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,ATLANTA,GA 30333, USA. NR 17 TC 15 Z9 15 U1 2 U2 2 PU AMER ACAD PEDIATRICS PI ELK GROVE VILLAGE PA 141 NORTH-WEST POINT BLVD, ELK GROVE VILLAGE, IL 60007-1098 SN 0031-4005 J9 PEDIATRICS JI Pediatrics PD MAR PY 1991 VL 87 IS 3 BP 361 EP 366 PG 6 WC Pediatrics SC Pediatrics GA FA981 UT WOS:A1991FA98100013 PM 2000276 ER PT J AU CHOO, QL RICHMAN, KH HAN, JH BERGER, K LEE, C DONG, C GALLEGOS, C COIT, D MEDINASELBY, A BARR, PJ WEINER, AJ BRADLEY, DW KUO, G HOUGHTON, M AF CHOO, QL RICHMAN, KH HAN, JH BERGER, K LEE, C DONG, C GALLEGOS, C COIT, D MEDINASELBY, A BARR, PJ WEINER, AJ BRADLEY, DW KUO, G HOUGHTON, M TI GENETIC ORGANIZATION AND DIVERSITY OF THE HEPATITIS-C VIRUS SO PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA LA English DT Article DE NON-A, NON-B HEPATITIS; RNA SEQUENCE; POLYPROTEIN; PESTIVIRUSES; FLAVIVIRIDAE ID NON-B-HEPATITIS; VIRAL DIARRHEA VIRUS; NUCLEOTIDE-SEQUENCE; NON-A; PUTATIVE HELICASES; MOLECULAR-CLONING; RNA; GENOME; FLAVIVIRUSES; PROTEINS AB The nucleotide sequence of the RNA genome of the human hepatitis C virus (HCV) has been determined from overlapping cDNA clones. The sequence (9379 nucleotides) has a single large open reading frame that could encode a viral polyprotein precursor of 3011 amino acids. While there is little overall amino acid and nucleotide sequence homology with other viruses, the 5' HCV nucleotide sequence upstream of this large open reading frame has substantial similarity to the 5' termini of pestiviral genomes. The polyprotein also has significant sequence similarity to helicases encoded by animal pestiviruses, plant potyviruses, and human flaviviruses, and it contains sequence motifs widely conserved among viral replicases and trypsin-like proteases. A basic, presumed nucleocapsid domain is located at the N terminus upstream of a region containing numerous potential N-linked glycosylation sites. These HCV domains are located in the same relative position as observed in the pestiviruses and flaviviruses and the hydrophobic profiles of all three viral polyproteins are similar. These combined data indicate that HCV is an unusual virus that is most related to the pestiviruses. Significant genome diversity is apparent within the putative 5' structural gene region of different HCV isolates, suggesting the presence of closely related but distinct viral genotypes. C1 CHIRON CORP,4560 HORTON ST,EMERYVILLE,CA 94608. CTR DIS CONTROL,ATLANTA,GA 30333. NR 32 TC 1522 Z9 1558 U1 5 U2 40 PU NATL ACAD SCIENCES PI WASHINGTON PA 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 SN 0027-8424 J9 P NATL ACAD SCI USA JI Proc. Natl. Acad. Sci. U. S. A. PD MAR PY 1991 VL 88 IS 6 BP 2451 EP 2455 DI 10.1073/pnas.88.6.2451 PG 5 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA FC216 UT WOS:A1991FC21600088 PM 1848704 ER PT J AU ROPER, WL AF ROPER, WL TI CURRENT APPROACHES TO PREVENTION OF HIV INFECTIONS SO PUBLIC HEALTH REPORTS LA English DT Article AB The HIV education and prevention strategy of the Centers for Disease Control has three principal components: (a) public information and education, (b) education for school-aged populations, and (c) risk reduction education and individual counseling and testing services for people at increased risk of HIV infection. The most visible components of the public information and education programs are the National Public Information Campaign ("America Responds to AIDS"), the National AIDS Hotline system, and the National AIDS Information Clearinghouse. Components of the youth education program consist of funding for national health and education organizations, funding for State and local education departments, training, surveillance of education efforts, and evaluation. Counseling and testing has entailed performance of approximately 2,500,000 HIV antibody tests with pre- and post-test counseling, notification and counseling of sexual and needle-sharing partners of those infected with HIV, and targeted risk reduction education through community-based organizations. Over time, these activities will continue to evolve and become more effective. RP ROPER, WL (reprint author), CTR DIS CONTROL,OFF PUBL AFFAIRS,PUBL HLTH SERV,MAIL STOP D25,ATLANTA,GA 30333, USA. NR 7 TC 22 Z9 22 U1 0 U2 0 PU US GOVERNMENT PRINTING OFFICE PI WASHINGTON PA SUPT OF DOCUMENTS, WASHINGTON, DC 20402-9325 SN 0033-3549 J9 PUBLIC HEALTH REP JI Public Health Rep. PD MAR-APR PY 1991 VL 106 IS 2 BP 111 EP 115 PG 5 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA FF817 UT WOS:A1991FF81700002 PM 1850530 ER PT J AU YIP, R FLESHOOD, L SPILLMAN, TC BINKIN, NJ WONG, FL TROWBRIDGE, FL AF YIP, R FLESHOOD, L SPILLMAN, TC BINKIN, NJ WONG, FL TROWBRIDGE, FL TI USING LINKED PROGRAM AND BIRTH RECORDS TO EVALUATE COVERAGE AND TARGETING IN TENNESSEES WIC PROGRAM SO PUBLIC HEALTH REPORTS LA English DT Article ID MISSOURI AB Public health nutrition programs are intended to serve low-income families who are at greater nutritional risk than the general population. Not all persons who are program-eligible are at equal risk, however. It would be desirable to evaluate a program's ability to enroll persons from higher risk backgrounds in the population (coverage) and, conversely, the extent to which those enrolled in this program are at higher risk (targeting). A method for the evaluation of coverage and targeting was developed using data from the Tennessee Women, Infants, and Children Special Supplemental Food Program (WIC) linked with birth certificates. The linked computer file was created by matching the name and date of birth in both record files. The birth records were the common source of information used to characterize the risk background for both the WIC and non-WIC participants. Maternal sociodemographic information on the birth records was used to definie the health risk background of each child. The coverage and targeting of "at-risk" children were computed and compared for 50 counties or county-aggregates in Tennessee. Considerable variation in the coverage and targeting rates of at-risk children was observed among Tennessee counties, although the counties within each WIC administrative region tended to have similar coverage and targeting patterns. Using the existing data in linked program and vital records provides a direct evaluation of a program. Coverage and targeting evaluation can be used to detect underserved populations within small geographic areas. C1 TENNESSEE DEPT HLTH & ENVIRONM,NUTR PROGRAM,NASHVILLE,TN. TENNESSEE DEPT HLTH & ENVIRONM,SUPPLEMENTAL FOOD PROGRAM,NASHVILLE,TN. TENNESSEE DEPT HLTH & ENVIRONM,DIV DATA UTILIZAT,NASHVILLE,TN. RP YIP, R (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV NUTR,ATLANTA,GA 30333, USA. NR 11 TC 1 Z9 1 U1 0 U2 1 PU US GOVERNMENT PRINTING OFFICE PI WASHINGTON PA SUPT OF DOCUMENTS, WASHINGTON, DC 20402-9325 SN 0033-3549 J9 PUBLIC HEALTH REP JI Public Health Rep. PD MAR-APR PY 1991 VL 106 IS 2 BP 176 EP 181 PG 6 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA FF817 UT WOS:A1991FF81700011 PM 1902310 ER PT J AU GRIFFIN, GE LEUNG, K FOLKS, TM KUNKEL, S NABEL, GJ AF GRIFFIN, GE LEUNG, K FOLKS, TM KUNKEL, S NABEL, GJ TI INDUCTION OF NF-CHI-B DURING MONOCYTE DIFFERENTIATION IS ASSOCIATED WITH ACTIVATION OF HIV-GENE EXPRESSION SO RESEARCH IN VIROLOGY LA English DT Article DE HIV, MONOCYTE, MACROPHAGE, AIDS, NF-CHI-B; PHORBOL ESTER, TNF-ALPHA, CELL MATURATION, TRANSCRIPTION ID HUMAN-IMMUNODEFICIENCY-VIRUS; NECROSIS FACTOR-ALPHA; KAPPA-B; MACROPHAGES; INFECTION; CELLS; LIPOPOLYSACCHARIDE; REPLICATION; CYTOKINES AB Cells of the monocyte-macrophage lineage are important targets of HIV infection. We report here that the phenotypic differentiation of monocyte cell lines induced by phorbol esters or tumour necrosis factor alpha (TNF-alpha) is associated with expression of nuclear factor kappa B (NF-chi-B). In parallel with such differentiation, HIV transcription, monitored using an HIV long terminal repeat reporter gene construct, is activated in such cells under the influence of enhanced NF-chi-B expression. Also, in a promonocyte cell line chronically infected with HIV, NF-chi-B expression and HIV transcription were enhanced on stimulation with phorbol ester or TNF-alpha. Thus, stimulation of monocyte cell lines by phorbol esters or TNF-alpha induces cell differentiation and activates HIV transcription. Such a process may have fundamental implications in AIDS pathogenesis in vivo and may be important in disease progression induced by opportunistic infections directly or indirectly involving macrophages. C1 UNIV MICHIGAN,MED CTR,HOWARD HUGHES MED INST,ANN ARBOR,MI 48109. CTR DIS CONTROL,RETROVIRUS DIS BRANCH,ATLANTA,GA 30333. UNIV MICHIGAN,SCH MED,DEPT PATHOL,ANN ARBOR,MI 48109. RP GRIFFIN, GE (reprint author), ST GEORGE HOSP,SCH MED,DIV COMMUNICABLE DIS,LONDON SW17 0RE,ENGLAND. FU Wellcome Trust NR 16 TC 48 Z9 48 U1 0 U2 0 PU EDITIONS SCIENTIFIQUES ELSEVIER PI PARIS CEDEX 15 PA 141 RUE JAVEL, 75747 PARIS CEDEX 15, FRANCE SN 0923-2516 J9 RES VIROLOGY JI Res. Virol. PD MAR-JUN PY 1991 VL 142 IS 2-3 BP 233 EP 238 DI 10.1016/0923-2516(91)90062-8 PG 6 WC Virology SC Virology GA FU977 UT WOS:A1991FU97700021 PM 1896645 ER PT J AU RICHET, HM ANDREMONT, A TANCREDE, C PICO, JL JARVIS, WR AF RICHET, HM ANDREMONT, A TANCREDE, C PICO, JL JARVIS, WR TI RISK-FACTORS FOR CANDIDEMIA IN PATIENTS WITH ACUTE LYMPHOCYTIC-LEUKEMIA SO REVIEWS OF INFECTIOUS DISEASES LA English DT Review ID HOSPITAL-ACQUIRED CANDIDEMIA; CANCER-PATIENTS; CANDIDIASIS; FUNGEMIA; DISSEMINATION; COLONIZATION; MORTALITY; FREQUENCY; ALBICANS AB Between 1983 and 1987 the overall incidence of candidemia at the Institut Gustave Roussy, a tertiary care referral hospital for patients with cancer, increased from 0.1% (7 of 6,801) to 0.32% (24 of 7,515) (P = .009). Because acute lymphocytic leukemia (ALL) was the most common underlying disease in patients with candidemia, risk factors for candidemia were analyzed in this subset of patients. A case-control study comparing the eight ALL patients who had candidemia with 18 ALL control patients revealed that previous bacteremia, prolonged neutropenia, prolonged fever, prolonged administration of antimicrobial agents, treatment with multiple antimicrobial agents, and a relatively high concentration of Candida organisms in stool were significant risk factors for candidemia. In a logistic regression analysis, however, only receipt of vancomycin and/or imipenem was identified as an independent risk factor for candidemia. Further analysis showed that administration of vancomycin promoted proliferation of Candida organisms in the gastrointestinal tract and that this proliferation was associated with an increased risk of candidemia. C1 CTR DIS CONTROL,CTR INFECT DIS,HOSP INFECT PROGRAM,MAIL STOP 10,ATLANTA,GA 30333. INST GUSTAVE ROUSSY,SERV MICROBIOL MED,F-94805 VILLEJUIF,FRANCE. INST GUSTAVE ROUSSY,DEPT HEMATOL,F-94805 VILLEJUIF,FRANCE. NR 14 TC 144 Z9 149 U1 0 U2 1 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0162-0886 J9 REV INFECT DIS PD MAR-APR PY 1991 VL 13 IS 2 BP 211 EP 215 PG 5 WC Immunology; Microbiology SC Immunology; Microbiology GA FD047 UT WOS:A1991FD04700004 PM 2041951 ER PT J AU MCLAUGHLIN, GL STIMAC, JE LUKE, JM KUHLENSCHMIDT, MS VERNON, RA MORTON, LD VISVESVARA, GS WHITELEY, HE AF MCLAUGHLIN, GL STIMAC, JE LUKE, JM KUHLENSCHMIDT, MS VERNON, RA MORTON, LD VISVESVARA, GS WHITELEY, HE TI DEVELOPMENT OF ACANTHAMOEBA-CORNEA COINCUBATION ASSAYS SO REVIEWS OF INFECTIOUS DISEASES LA English DT Meeting Abstract C1 CTR DIS CONTROL,DIV PARASITOL,ATLANTA,GA 30333. UNIV ILLINOIS,COLL VET MED,URBANA,IL 61801. FU NEI NIH HHS [EY08205, EY07651] NR 4 TC 5 Z9 5 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0162-0886 J9 REV INFECT DIS PD MAR-APR PY 1991 VL 13 SU 5 BP S397 EP S398 PG 2 WC Immunology; Microbiology SC Immunology; Microbiology GA FD060 UT WOS:A1991FD06000011 PM 1675479 ER PT J AU VISVESVARA, GS AF VISVESVARA, GS TI CLASSIFICATION OF ACANTHAMOEBA SO REVIEWS OF INFECTIOUS DISEASES LA English DT Article; Proceedings Paper CT INTERNATIONAL SYMP ON ACANTHAMOEBA AND THE EYE CY APR 14-16, 1989 CL HOUSTON, TX SP ALLERGAN ID MORPHOLOGY; AMOEBIDA AB Members of the genus Acanthamoeba are being isolated with increasing frequency from clinical specimens, especially contact lens solutions. Although the genus was first established in 1931, considerable confusion about its taxonomic classification existed in the literature until recently. A brief commentary on this confusion is provided, and the taxonomic classifications of Acanthamoeba and the three groups of species are described. RP VISVESVARA, GS (reprint author), CTR DIS CONTROL,CTR INFECT DIS,PARASIT DIS BRANCH,DIV PARASIT DIS,1600 CLIFTON RD NE,ATLANTA,GA 30333, USA. NR 21 TC 58 Z9 60 U1 1 U2 1 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0162-0886 J9 REV INFECT DIS PD MAR-APR PY 1991 VL 13 SU 5 BP S369 EP S372 PG 4 WC Immunology; Microbiology SC Immunology; Microbiology GA FD060 UT WOS:A1991FD06000002 PM 2047665 ER PT J AU RIEDO, FX BROOME, CV AF RIEDO, FX BROOME, CV TI MENINGOCOCCAL DISEASE - A REVIEW SO SAUDI MEDICAL JOURNAL LA English DT Review AB Invasive meningococcal disease continues to cause significant morbidity and mortality, particularly in the developing world. This review focuses on the epidemiology, clinical syndromes, therapy, and prevention of meningococcal disease. Future progress will depend on an improved understanding of the epidemiology of both endemic and epidemic disease. Prevention will be enhanced by the development of effective, long-lasting vaccines against all the major meningococcal serogroups, particularly serogroup B. RP RIEDO, FX (reprint author), CTR DIS CONTROL,CTR INFECT DIS,MENINGITIS & SPECIAL BRANCH,ATLANTA,GA 30333, USA. NR 0 TC 1 Z9 1 U1 0 U2 0 PU SAUDI MED J DEPT OF EXP PATH PI LONDON PA ST BARTHOLOMEW'S HOSP, LONDON, UNITED KINGDOM EC1A 7BE SN 0379-5284 J9 SAUDI MED J JI Saudi Med. J. PD MAR PY 1991 VL 12 IS 2 BP 77 EP 83 PG 7 WC Medicine, General & Internal SC General & Internal Medicine GA FC411 UT WOS:A1991FC41100002 ER PT J AU STETTLER, LE PLATEK, SF RILEY, RD MASTIN, JP SIMON, SD AF STETTLER, LE PLATEK, SF RILEY, RD MASTIN, JP SIMON, SD TI LUNG PARTICULATE BURDENS OF SUBJECTS FROM THE CINCINNATI, OHIO URBAN AREA SO SCANNING MICROSCOPY LA English DT Article DE HUMAN LUNG PARTICLE CONTENT; AUTOMATED PARTICLE ANALYSIS; NONFIBROUS MINERAL PARTICLES; ELECTRON MICROSCOPIC PARTICLE ANALYSIS; QUANTITATIVE ANALYSIS ID MINERAL PARTICLES; GENERAL-POPULATION; ASBESTOS FIBERS; PLEURAL PLAQUES; TISSUE; MESOTHELIOMA; CLEARANCE; DUST AB Because of the relatively small data base existing for lung particulate burdens of subjects with no overt pneumoconioses, the total exogenous lung particulate concentrations of 91 subjects from the Cincinnati, Ohio urban area were determined using an automated scanning electron microscope-energy dispersive x-ray analysis-image analysis system. Four of these subjects were foundry workers and had the highest exogenous particle concentrations seen in the 91 lungs, ranging from 1860 to 2990 x 10(6) particles per gram of dry lung (ppg). The average exogenous particle concentration for the remaining 87 subjects was 476 +/- 380 x 10(6) ppg with a range of 71 to 1860 x 10(6) ppg. The median size of the exogenous particles in the 87 lungs was narrow, ranging from 0.37 to 1.02-mu-m. The geometric mean particle size over all 87 lungs was 0.60-mu-m with a geometric standard deviation (sigma-g) of 2.35. The total exogenous particle levels were elevated for the male subjects compared to females (p = 0.015), and were positively associated with age (p = 0.021). However, no correlation was seen between total particle concentration and race or smoking history. RP STETTLER, LE (reprint author), NIOSH,DIV BIOMED & BEHAV SCI,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 25 TC 17 Z9 17 U1 2 U2 2 PU SCANNING MICROSCOPY INT PI CHICAGO PA PO BOX 66507, AMF O'HARE, CHICAGO, IL 60666 SN 0891-7035 J9 SCANNING MICROSCOPY JI Scanning Microsc. PD MAR PY 1991 VL 5 IS 1 BP 85 EP 94 PG 10 WC Microscopy SC Microscopy GA FH432 UT WOS:A1991FH43200009 PM 1647057 ER PT J AU ADDISS, DG EBERHARD, ML LAMMIE, PJ HITCH, WL SPENCER, HC AF ADDISS, DG EBERHARD, ML LAMMIE, PJ HITCH, WL SPENCER, HC TI TOLERANCE OF SINGLE HIGH-DOSE IVERMECTIN FOR TREATMENT OF LYMPHATIC FILARIASIS SO TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE LA English DT Note RP ADDISS, DG (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,PARASIT DIS BRANCH,MAILSTOP F13,ATLANTA,GA 30333, USA. NR 3 TC 18 Z9 18 U1 0 U2 0 PU ROYAL SOC TROPICAL MEDICINE PI LONDON PA MANSON HOUSE 26 PORTLAND PLACE, LONDON, ENGLAND W1N 4EY SN 0035-9203 J9 T ROY SOC TROP MED H JI Trans. Roy. Soc. Trop. Med. Hyg. PD MAR-APR PY 1991 VL 85 IS 2 BP 265 EP 266 DI 10.1016/0035-9203(91)90049-5 PG 2 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA FN691 UT WOS:A1991FN69100037 PM 1887489 ER PT J AU JALIL, F ZAMAN, S CARLSSON, B GLASS, RI KAPIKIAN, AZ MELLANDER, L HANSON, LA AF JALIL, F ZAMAN, S CARLSSON, B GLASS, RI KAPIKIAN, AZ MELLANDER, L HANSON, LA TI IMMUNOGENICITY AND REACTOGENICITY OF RHESUS ROTAVIRUS VACCINE GIVEN IN COMBINATION WITH ORAL OR INACTIVATED POLIOVIRUS VACCINES AND DIPHTHERIA-TETANUS-PERTUSSIS VACCINE SO TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID YOUNG-CHILDREN; INFANTS; LIVE; GASTROENTERITIS; RIT-4237; IMMUNIZATION; ANTIBODIES; DIARRHEA; TRIAL AB Immunogenicity and reactogenicity of the oral rhesus rotavirus vaccine (RRV) were assessed among 72 infants (6 weeks old) in Lahore, Pakistan, from August to December 1985. Special emphasis was placed on the possible interaction or interference caused by giving RRV at the time infants received their first polio immunization. RRV was given to the infants at the same time as diphtheria-tetanus-pertussis (DTP), oral poliovirus vaccine (OPV), or inactivated poliovirus vaccine (IPV). The immune response to RRV was assessed by plaque-reduction neutralization 3 weeks after immunization and serum immunoglobulin (Ig) G and IgA antibody levels to poliovirus type 1 were tested by enzyme-linked immunosorbent assay (ELISA) after polio immunizations. Of the infants in the group given RRV with OPV, 50% had a two- to four-fold rise in neutralization titre against rotavirus, compared with 22% in the group given RRV with DTP and 20% in the group given RRV and IPV (P < 0.05). Interference by live oral polio vaccination in the response to RRV seems unlikely. We observed no significant difference in rates of seroconversion of IgG antibodies to poliovirus type 1 among infants aged 18 and 21 weeks who received RRV and OPV (81%), RRV with delayed OPV (67%), or RRV and IPV (59%). Administration of RRV was safe and was not associated with adverse reactions in the 6 weeks old infants. The low rate of seroconversion to rotavirus suggests that a more antigen-rich vaccine or multiple doses of the same vaccine might produce a better immune response. C1 GOTHENBURG UNIV,DEPT CLIN IMMUNOL,S-41346 GOTHENBURG,SWEDEN. GOTHENBURG UNIV,DEPT PAEDIAT,S-41346 GOTHENBURG,SWEDEN. CTR DIS CONTROL,VIRAL GASTROENTERITIS UNIT,ATLANTA,GA 30333. NIAID,INFECT DIS LAB,BETHESDA,MD 20892. RP JALIL, F (reprint author), KING EDWARD MED COLL,DEPT SOCIAL & PREVENT PAEDIAT,LAHORE,PAKISTAN. NR 33 TC 11 Z9 11 U1 1 U2 1 PU ROYAL SOC TROPICAL MEDICINE PI LONDON PA MANSON HOUSE 26 PORTLAND PLACE, LONDON, ENGLAND W1N 4EY SN 0035-9203 J9 T ROY SOC TROP MED H JI Trans. Roy. Soc. Trop. Med. Hyg. PD MAR-APR PY 1991 VL 85 IS 2 BP 292 EP 296 DI 10.1016/0035-9203(91)90061-3 PG 5 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA FN691 UT WOS:A1991FN69100046 PM 1653474 ER PT J AU ANDERSEN, FL TOLLEY, HD SCHANTZ, PM CHI, P LIU, F DING, Z AF ANDERSEN, FL TOLLEY, HD SCHANTZ, PM CHI, P LIU, F DING, Z TI CYSTIC ECHINOCOCCOSIS IN THE XINJIANG - UYGUR AUTONOMOUS REGION, PEOPLES-REPUBLIC-OF-CHINA .2. COMPARISON OF 3 LEVELS OF A LOCAL PREVENTIVE AND CONTROL PROGRAM SO TROPICAL MEDICINE AND PARASITOLOGY LA English DT Article ID HYDATID DISEASES; CENTRAL UTAH; GRANULOSUS; DOGS AB A project to compare different levels of a hydatid disease control program was instigated and evaluated in 16 randomly selected villages in the Xinjiang/Uygur Autonomous Region, PRC (China). Factors tested included the effect of: 1) the role of a village hydatid disease control officer, 2) the use of praziquantel-medicated "bait" tablets for treatment of Echinococcus granulosus tapeworms in dogs, and 3) the use of educational materials for children and adults. Evaluation of contrasting treatment levels was done by determining infection rates of E. granulosus in about 25 dogs examined from each of the 16 villages before and after the trial period, and by use of pre- and post-treatment questionnaires distributed to 40 randomly selected households in each village. Optimum results were obtained in those villages which received medicated tablets and support visits from a control officer on a monthly basis (so-called "moderate intervention level"). C1 CTR DIS CONTROL,ATLANTA,GA 30333. ACAD ANIM SCI,VET RES INST,URUMQI,PEOPLES R CHINA. NATL HYDATID DIS CTR CHINA,URUMQI,PEOPLES R CHINA. XINJIANG MED COLL,URUMQI,PEOPLES R CHINA. RP ANDERSEN, FL (reprint author), BRIGHAM YOUNG UNIV,DEPT ZOOL,574 WIDTSOE BLDG,PROVO,UT 84602, USA. NR 27 TC 15 Z9 17 U1 0 U2 3 PU GEORG THIEME VERLAG PI STUTTGART PA P O BOX 30 11 20, D-70451 STUTTGART, GERMANY SN 0177-2392 J9 TROP MED PARASITOL JI Trop. Med. Parasitol. PD MAR PY 1991 VL 42 IS 1 BP 1 EP 10 PG 10 WC Parasitology; Tropical Medicine SC Parasitology; Tropical Medicine GA FF242 UT WOS:A1991FF24200001 PM 2052848 ER PT J AU MORRISON, HG GOLDSMITH, CS REGNERY, HL AUPERIN, DD AF MORRISON, HG GOLDSMITH, CS REGNERY, HL AUPERIN, DD TI SIMULTANEOUS EXPRESSION OF THE LASSA VIRUS-N AND GPC GENES FROM A SINGLE RECOMBINANT VACCINIA VIRUS SO VIRUS RESEARCH LA English DT Article DE LASSA STRUCTURAL PROTEINS; RECOMBINANT VACCINIA VIRUS; VACCINIA TRANSFER VECTOR ID GUINEA-PIGS; VECTORS; CONSTRUCTION; BACULOVIRUS; PROTECTION; SEQUENCE; CLONING; DNA AB A new transfer vector was constructed that directs the insertion of two heterologous genes into the vaccinia virus thymidine kinase (TK) gene during a single recombination event. This vector, pDAVAC2, contains bidirectional vaccinia P7.5 early/late promoter elements and two unique cloning sites. cDNA clones containing the complete coding sequences for the Lassa virus (Josiah strain) nucleoprotein (N) and glycoprotein (GPC) genes were inserted into the vaccinia TK gene using this transfer vector. The recombinant virus, V-LSGN-II, expressed proteins in cell culture that appeared to be authentic with respect to electrophoretic mobility, glycosylation, and post-translational cleavage. Indirect immunofluorescence (IFA) of recombinant virus-infected cells demonstrated both the bright granular and diffuse patterns of staining characteristic of the Lassa nucleoprotein and glycoprotein, respectively. Electron-dense inclusion bodies typical of arenavirus-infected cells were observed by electron microscopy in V-LSN and V-LSGN-II-infected cells, but not in V-LSGPC-infected cells. Mice inoculated with V-LSGN-II by intraperitoneal injection developed serum antibodies that reacted with authentic Lassa proteins in immunofluorescence and radioimmune precipitation assays. This recombinant virus represents an additional candidate for a Lassa fever vaccine and demonstrates the feasibility of expressing any two genes of interest in a single recombinant vaccinia virus through the use of the transfer vector pDAVAC2. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL DIS,ATLANTA,GA 30333. OI Morrison, Hilary/0000-0003-0281-326X NR 16 TC 13 Z9 13 U1 1 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0168-1702 J9 VIRUS RES JI Virus Res. PD MAR PY 1991 VL 18 IS 2-3 BP 231 EP 241 DI 10.1016/0168-1702(91)90021-M PG 11 WC Virology SC Virology GA FC904 UT WOS:A1991FC90400011 PM 2042398 ER PT J AU HIBBS, J PERPER, J WINEK, CL AF HIBBS, J PERPER, J WINEK, CL TI AN OUTBREAK OF DESIGNER DRUG RELATED DEATHS IN PENNSYLVANIA SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Note ID PHARMACOKINETICS; FENTANYL AB 3-Methylfentanyl ("China White") is a "designer" opiate that has caused more than 100 overdose deaths in California since 1979, but that has not been associated previously with deaths east of the Rocky Mountains. During 1988, 3-methylfentanyl was identified in 16 fatal overdose cases in Allegheny County, Pennsylvania, contributing to a fourfold rise in overdose mortality during October of that year. Morphine was detected in the blood of five persons (31%) and cocaine in the blood of three persons (19%) dying of 3-methylfentanyl overdoses; these were demographically similar to 99 other fatal overdose cases investigated by the county coroner from 1986 through 1988. This documents the contribution of 3-methylfentanyl to overdose mortality in an eastern city and the use of 3-methylfentanyl with other illegal drugs. Drug abusers in the northeastern United States should be considered at risk for more "designer drug" overdose outbreaks in the future. C1 CTR DIS CONTROL,DIV FIELD SERV,EPIDEMIOL PROGRAM OFF,ATLANTA,GA 30333. ALLEGHENY CTY CORONERS OFF,PITTSBURGH,PA. ALLEGHENY CTY DEPT LABS,PITTSBURGH,PA. NR 11 TC 28 Z9 28 U1 4 U2 5 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD FEB 27 PY 1991 VL 265 IS 8 BP 1011 EP 1013 DI 10.1001/jama.265.8.1011 PG 3 WC Medicine, General & Internal SC General & Internal Medicine GA EY432 UT WOS:A1991EY43200031 PM 1867667 ER PT J AU EBERHARD, ML BRANDT, FH KAISER, RL AF EBERHARD, ML BRANDT, FH KAISER, RL TI CHLORTETRACYCLINE FOR DRACUNCULIASIS SO LANCET LA English DT Letter C1 CTR DIS CONTROL,WHO,COLLABORATING CTR RES TRAINING & ERADICAT DRACUNCULIASIS,ATLANTA,GA 30333. RP EBERHARD, ML (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,ATLANTA,GA 30333, USA. NR 5 TC 3 Z9 3 U1 0 U2 0 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD FEB 23 PY 1991 VL 337 IS 8739 BP 500 EP 500 DI 10.1016/0140-6736(91)93444-E PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EY887 UT WOS:A1991EY88700060 PM 1671508 ER PT J AU HENEINE, W KAPLAN, JE GRACIA, F LAL, R ROBERTS, B LEVINE, PH REEVES, WC AF HENEINE, W KAPLAN, JE GRACIA, F LAL, R ROBERTS, B LEVINE, PH REEVES, WC TI HTLV-II ENDEMICITY AMONG GUAYMI INDIANS IN PANAMA SO NEW ENGLAND JOURNAL OF MEDICINE LA English DT Letter ID INFECTION C1 GORGAS MEM LAB,PANAMA CITY,PANAMA. CTR DIS CONTROL,ATLANTA,GA 30333. NCI,BETHESDA,MD 20892. RP HENEINE, W (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 9 TC 61 Z9 62 U1 0 U2 0 PU MASS MEDICAL SOC PI BOSTON PA 10 SHATTUCK, BOSTON, MA 02115 SN 0028-4793 J9 NEW ENGL J MED JI N. Engl. J. Med. PD FEB 21 PY 1991 VL 324 IS 8 BP 565 EP 565 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EX918 UT WOS:A1991EX91800024 PM 1992314 ER PT J AU SERDULA, M WILLIAMSON, DF KENDRICK, JS ANDA, RF BYERS, T AF SERDULA, M WILLIAMSON, DF KENDRICK, JS ANDA, RF BYERS, T TI TRENDS IN ALCOHOL-CONSUMPTION BY PREGNANT-WOMEN - 1985 THROUGH 1988 SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article ID CIGARETTE; PATTERNS; DRINKING; SMOKING AB To examine trends in alcohol consumption among pregnant women, we examined data collected from 21 states participating in the Behavioral Risk Factor Surveillance System for 4 consecutive years: 1985 through 1988. Overall, 429 (25%) of 1712 pregnant women and 19 903 (55%) of 36 057 nonpregnant women 18 to 45 years of age reported using alcohol in the previous month. Pregnant women who used any alcohol reported consuming a median of four drinks per month, whereas nonpregnant women who used any alcohol reported nine. The prevalence of alcohol consumption among pregnant women declined steadily, from 32% in 1985 to 20% in 1988, but the median number of drinks per month for pregnant women who drank did not change. No decline was observed among the less educated or those under the age of 25 years. In 1988, the prevalence of alcohol use among pregnant women remained highest among smokers (37%) and the unmarried (28%). Although the overall consumption of alcohol by pregnant women in the United States appears to be declining, special efforts are needed to reduce alcohol use among pregnant women who are smokers, unmarried, less educated, or younger, women who may already be at high risk of a poor pregnancy outcome. C1 CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV REPROD HLTH,ATLANTA,GA 30333. CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,ATLANTA,GA 30333. RP SERDULA, M (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV NUTR K26,ATLANTA,GA 30333, USA. NR 20 TC 85 Z9 85 U1 0 U2 4 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD FEB 20 PY 1991 VL 265 IS 7 BP 876 EP 879 DI 10.1001/jama.265.7.876 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA EX587 UT WOS:A1991EX58700038 PM 1992184 ER PT J AU FRADKIN, JE SCHONBERGER, LB MILLS, JL GUNN, WJ PIPER, JM WYSOWSKI, DK THOMSON, R DURAKO, S BROWN, P AF FRADKIN, JE SCHONBERGER, LB MILLS, JL GUNN, WJ PIPER, JM WYSOWSKI, DK THOMSON, R DURAKO, S BROWN, P TI CREUTZFELDT-JAKOB DISEASE IN PITUITARY GROWTH-HORMONE RECIPIENTS IN THE UNITED-STATES SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article ID THERAPY; FRANCE AB To assess the magnitude of Creutzfeldt-Jakob disease (CJD) occurrence among recipients of pituitary-derived human growth hormone (HGH), we conducted an epidemiologic follow-up of 6284 recipients of HGH distributed through the National Hormone and Pituitary Program. Seven neuropathologically confirmed cases of CJD have occurred in this population to date: six patients with clinical CJD presented with ataxia and imbalance, rather than with altered mentation, which is the most common initial manifestation in sporadic CJD, and one patient died in the preclinical incubation state of the disease. All seven cases occurred among the nearly 700 HGH recipients who started therapy before 1970. Since only 10% of the cohort has been followed up for the 15-year average incubation interval from midpoint of HGH treatment to onset of symptoms, the great majority of potentially exposed patients have not yet attained the requisite incubation period for expression of CJD. The median duration of HGH therapy of 100 months in the CJD cases was significantly longer than 41 months for all patients starting treatment before 1970; thus, the duration of pituitary HGH therapy is a major risk factor for CJD. C1 CTR DIS CONTROL,ATLANTA,GA 30333. NICHHD,BETHESDA,MD 20892. US FDA,ROCKVILLE,MD 20857. WESTAT CORP,ROCKVILLE,MD. NINCDS,BETHESDA,MD 20892. RP FRADKIN, JE (reprint author), NIDDKD,ENDOCRINOL & METAB DIS PROGRAMS BRANCH,WESTWOOD BLDG,ROOM 603,BETHESDA,MD 20892, USA. NR 28 TC 121 Z9 123 U1 0 U2 5 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD FEB 20 PY 1991 VL 265 IS 7 BP 880 EP 884 DI 10.1001/jama.265.7.880 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA EX587 UT WOS:A1991EX58700039 PM 1992185 ER PT J AU SMITH, MJ MAZZOLA, EP FARRELL, TJ SPHON, JA PAGE, SW ASHLEY, D SIRIMANNE, SR HILL, RH NEEDHAM, LL AF SMITH, MJ MAZZOLA, EP FARRELL, TJ SPHON, JA PAGE, SW ASHLEY, D SIRIMANNE, SR HILL, RH NEEDHAM, LL TI 1,1'-ETHYLIDENEBIS(L-TRYPTOPHAN), STRUCTURE DETERMINATION OF CONTAMINANT-97 - IMPLICATED IN THE EOSINOPHILIA-MYALGIA-SYNDROME (EMS) SO TETRAHEDRON LETTERS LA English DT Article AB The condensation of tryptophan and acetaldehyde affords a bisindolylaminal of tryptophan which is indistinguishable from contaminant "97". The formation and decomposition of aminals is addressed in light of epidemiological evidence linking them to a recent outbreak of EMS. C1 US FDA,CTR FOOD SAFETY & APPL NUTR,FOOD FORMULAT BRANCH,WASHINGTON,DC 20204. CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,TOXICOL BRANCH,ATLANTA,GA 30333. RP SMITH, MJ (reprint author), US FDA,CTR FOOD SAFETY & APPL NUTR,NAT PROD & INSTRUMENTAT BRANCH,WASHINGTON,DC 20204, USA. RI Needham, Larry/E-4930-2011 NR 19 TC 54 Z9 54 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0040-4039 J9 TETRAHEDRON LETT JI Tetrahedron Lett. PD FEB 18 PY 1991 VL 32 IS 8 BP 991 EP 994 DI 10.1016/S0040-4039(00)74469-8 PG 4 WC Chemistry, Organic SC Chemistry GA EZ574 UT WOS:A1991EZ57400003 ER PT J AU GELLIN, BG BROOME, CV BIBB, WF WEAVER, RE GAVENTA, S MASCOLA, L AF GELLIN, BG BROOME, CV BIBB, WF WEAVER, RE GAVENTA, S MASCOLA, L TI THE EPIDEMIOLOGY OF LISTERIOSIS IN THE UNITED-STATES-1986 SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Article DE LISTERIA-MONOCYTOGENES; MENINGITIS; PREGNANCY; SEPTICEMIA ID ACQUIRED IMMUNODEFICIENCY SYNDROME; MULTILOCUS ENZYME ELECTROPHORESIS; UNITED-STATES; MONOCYTOGENES MENINGITIS; IRON OVERLOAD; INFECTION; OUTBREAK; PHAGOCYTOSIS; CHEESE AB To determine the morbidity and mortality due to listeriosis in the United States, the authors undertook an active surveillance project in 1986 to identify all cases in which Listeria monocytogenes was isolated from cultures of ordinarily sterile sites in a population of 34 million persons. The authors estimated that at least 1,700 cases of listeriosis and 450 deaths occurred in the United States in 1986; 27% of these cases occurred in pregnant women, with 22% of perinatal cases resulting in stillbirths or neonatal deaths. The risk of listeriosis in adults (0.5 per 100,000 population) was similar in all regions studied; the incidence of perinatal listeriosis was three times higher in Los Angeles County, California, than in the other areas (24.3/100,000 live births vs. 7.8/100,000 live births). Geographic variation may have resulted from underdiagnosis of perinatal listeriosis in five of the study areas. Multilocus electrophoretic enzyme typing was useful for elucidating the molecular epidemiology of L. monocytogenes; perinatal listeriosis was significantly associated with one group of related strains. Multilocus electrophoretic enzyme typing also identified three clusters representing possible common-source outbreaks. These findings document the substantial morbidity due to listeriosis in the United States; to the extent that sporadic listeriosis is foodborne, this morbidity could be reduced by appropriate preventive measures, particularly in persons known to be at increased risk of infection. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,MENINGITIS & SPECIAL PATHOGENS BRANCH,ATLANTA,GA 30333. LOS ANGELES CTY DEPT HLTH SERV,LOS ANGELES,CA. NR 39 TC 115 Z9 118 U1 0 U2 2 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD FEB 15 PY 1991 VL 133 IS 4 BP 392 EP 401 PG 10 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EZ157 UT WOS:A1991EZ15700010 PM 1899779 ER PT J AU HOPKINS, RS JURANEK, DD AF HOPKINS, RS JURANEK, DD TI ACUTE GIARDIASIS - AN IMPROVED CLINICAL CASE DEFINITION FOR EPIDEMIOLOGIC STUDIES SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Article DE DISEASE OUTBREAKS; EPIDEMIOLOGIC METHODS; GIARDIASIS; WATER SUPPLY ID COMMUNITY-WIDE OUTBREAK; WATERBORNE GIARDIASIS AB In June 1983, an outbreak of waterborne giardiasis occurred in a group of 93 university students and faculty participating in a geology field course in Colorado. All cases occurred in one subgroup of persons who were heavily exposed to untreated stream water on a field trip, and the risk of illness was strongly related to the amount of untreated stream water consumed. The median incubation period from a brief exposure to the first symptom was 7 days. The authors compared symptoms and stool sample results among 31 Giardia-positive persons in the exposed group and 36 Giardia-negative participants in an unexposed group to assess several case definitions for acute giardiasis. Diarrhea, abdominal cramps, flatulence, foul-smelling stools, nausea, excessive tiredness, bloating, anorexia, and chills were each significantly more common in the first group than in the second. A giardiasis case definition of 5 days or more of diarrhea-the definition used in many epidemiologic studies of giardiasis-had a specificity of 100 percent but a sensitivity of only 32.2 percent compared with a definition based on results of stool examinations. When a case was defined as an illness lasting 7 days or more, with a combination of two or more of six symptoms (diarrhea, flatulence, foul-smelling stools, nausea, abdominal cramps, and excessive tiredness), sensitivity rose to 73 percent, with a specificity of 88 percent. Such a case definition may be an improvement over that of 5 days of diarrhea, especially in outbreaks where there is good laboratory documentation that Giardia is the etiologic agent. The definition should be validated in other outbreaks and in situations where giardiasis must be distinguished from gastrointestinal disease caused by other agents. C1 COLORADO DEPT HLTH,DIV EPIDEMIOL & DIS CONTROL,COMMUNICABLE DIS CONTROL SECT,DENVER,CO. CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,ATLANTA,GA 30333. NR 6 TC 18 Z9 18 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD FEB 15 PY 1991 VL 133 IS 4 BP 402 EP 407 PG 6 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EZ157 UT WOS:A1991EZ15700011 PM 1994703 ER PT J AU BRYAN, RT VISVESVARA, GS AF BRYAN, RT VISVESVARA, GS TI COCCIDIA AND MICROSPORIDIA SO ANNALS OF INTERNAL MEDICINE LA English DT Letter RP BRYAN, RT (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 5 TC 2 Z9 2 U1 0 U2 0 PU AMER COLL PHYSICIANS PI PHILADELPHIA PA INDEPENDENCE MALL WEST 6TH AND RACE ST, PHILADELPHIA, PA 19106-1572 SN 0003-4819 J9 ANN INTERN MED JI Ann. Intern. Med. PD FEB 15 PY 1991 VL 114 IS 4 BP 343 EP 343 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EX521 UT WOS:A1991EX52100039 PM 1987889 ER PT J AU PILCHER, JB TSANG, VCW ZHOU, W BLACK, CM SIDMAN, C AF PILCHER, JB TSANG, VCW ZHOU, W BLACK, CM SIDMAN, C TI OPTIMIZATION OF BINDING-CAPACITY AND SPECIFICITY OF PROTEIN-G ON VARIOUS SOLID MATRICES FOR IMMUNOGLOBULINS SO JOURNAL OF IMMUNOLOGICAL METHODS LA English DT Article DE STAPHYLOCOCCAL PROTEIN-A; STREPTOCOCCAL PROTEIN-G; IMMUNOGLOBULIN PURIFICATION ID IGG-BINDING; ANTIBODIES; ANTIGENS AB Streptococcal protein G is a more versatile and efficient alternative to staphylococcal protein A in purifying immunoglobin G (IgG) isotypes from various animal species. Optimizations are most dramatic with goat IgG, which binds protein G 55 times better than protein A. Using GammaBind G (a recombinant form of protein G (Genex Corp.)), we optimized binding capacity and specificity for IgG. Protein G was covalently coupled to three different matrices (CNBr-Sepharose, Tresyl-Sepharose, and Affigel-10) and compared with protein A-CNBr-Sepharose. Equal volumes of human, mouse, and goat serum samples were equilibrated into Hepes/NaOH buffers with various ionic strengths (i.e., concentrations of NaCl) and pH values and allowed to bind to affinity columns of proteins G and A. Bound ligands were eluted with 8.0 M urea, 0.05-M Tris/HCl, pH 8.00. Bound fractions were assayed for protein concentration and analyzed by sodium dodecyl sulfate polyacrylamide electrophoresis. The optimal conditions for binding IgG to protein G are 1.0 M NaCl and pH 8.0 for human, mouse, and goat. C1 JACKSON LAB,BAR HARBOR,ME 04609. CTR DIS CONTROL,CTR INFECT DIS,DIV IMMUNOL ONCOL & HEMATOL DIS,ATLANTA,GA 30333. RP PILCHER, JB (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DEPT PARASIT DIS,PARASIT DIS BRANCH,BLDG 23,ROOM 1003,ATLANTA,GA 30333, USA. FU NCI NIH HHS [CA35845]; PHS HHS [A125765, A120232] NR 18 TC 13 Z9 13 U1 0 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0022-1759 J9 J IMMUNOL METHODS JI J. Immunol. Methods PD FEB 15 PY 1991 VL 136 IS 2 BP 279 EP 286 DI 10.1016/0022-1759(91)90014-7 PG 8 WC Biochemical Research Methods; Immunology SC Biochemistry & Molecular Biology; Immunology GA EY993 UT WOS:A1991EY99300014 PM 1999655 ER PT J AU WOODRUFF, BA PAVIA, AT BLAKE, PA AF WOODRUFF, BA PAVIA, AT BLAKE, PA TI A NEW LOOK AT TYPHOID VACCINATION - INFORMATION FOR THE PRACTICING PHYSICIAN SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article ID VI-CAPSULAR POLYSACCHARIDE; CONTROLLED FIELD TRIAL; SALMONELLA-TYPHI; TY21A; FEVER; PREVENTION AB Most cases of typhoid fever in the United States occur in international travelers, with the greatest risk associated with travel to Peru, India, Pakistan, and Chile. Laboratory workers and household contacts of long-term carriers are also at greater risk than the general population. Decisions to the use typhoid vaccine involve weighing the risk of illness against the risk of vaccine reactions. Until recently, the only typhoid vaccine commercially available to US civilians was a heat-phenol-inactivated parenteral product that is 51% to 77% effective in preventing typhoid fever but frequently produces local pain and swelling, fever, headache, and malaise. A new orally administered, live-attenuated vaccine, made from the Ty21 a strain of Salmonella typhi, has been recently licensed in the United States. This vaccine provides equivalent protection with a much lower incidence of adverse reactions. It is administered in a four-dose series given over 7 days. Since neither vaccine offers total protection, the most important elements in prevention of typhoid fever remain sound biosafety precautions in laboratory workers and care in selecting food and beverages by those traveling to areas where typhoid fever is endemic. RP WOODRUFF, BA (reprint author), CTR DIS CONTROL,DIV BACTERIAL DIS,1600 CLIFTON RD NE,MAILSTOP C-09,ATLANTA,GA 30333, USA. NR 29 TC 28 Z9 28 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD FEB 13 PY 1991 VL 265 IS 6 BP 756 EP 759 DI 10.1001/jama.265.6.756 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA EW479 UT WOS:A1991EW47900029 PM 1990193 ER PT J AU CHAROENVIT, Y COLLINS, WE JONES, TR MILLET, P YUAN, L CAMPBELL, GH BEAUDOIN, RL BRODERSON, JR HOFFMAN, SL AF CHAROENVIT, Y COLLINS, WE JONES, TR MILLET, P YUAN, L CAMPBELL, GH BEAUDOIN, RL BRODERSON, JR HOFFMAN, SL TI INABILITY OF MALARIA VACCINE TO INDUCE ANTIBODIES TO A PROTECTIVE EPITOPE WITHIN ITS SEQUENCE SO SCIENCE LA English DT Article ID PLASMODIUM-VIVAX; CIRCUMSPOROZOITE PROTEIN; IMMUNODOMINANT EPITOPE; MONOCLONAL-ANTIBODIES; PEPTIDE-SYNTHESIS; FALCIPARUM; ANTIGEN; SPOROZOITES; INFECTION; EFFICACY AB Saimiri monkeys immunized with a recombinant protein containing 20 copies of the nine amino acid repeat of the Plasmodium vivax circumsporozoite (CS) protein developed high concentrations of antibodies to the repeat sequence and to sporozoites, but were not protected against challenge. After intravenous injection of an immunoglobulin G3 monoclonal antibody (NVS3) against irradiated P. vivax sporozoites, four of six monkeys were protected against sporozoite-induced malaria, and the remaining two animals took significantly longer to become parasitemic. Epitope mapping demonstrated that NVS3 recognizes only four (AGDR) of the nine amino acids within the repeat region of the P. vivax CS protein. The monkeys immunized with (DRA(D)(A)GQPAG)20 did not produce antibodies to the protective epitope AGDR. Thus, determination of the fine specificity of protective immune responses may be critical to the construction of successful subunit vaccines. C1 USN,MED RES INST,DEPT INFECT DIS,BETHESDA,MD 20889. CTR DIS CONTROL,MALARIA BRANCH,ATLANTA,GA 30333. NR 25 TC 78 Z9 78 U1 0 U2 3 PU AMER ASSOC ADVANCEMENT SCIENCE PI WASHINGTON PA 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 SN 0036-8075 J9 SCIENCE JI Science PD FEB 8 PY 1991 VL 251 IS 4994 BP 668 EP 671 DI 10.1126/science.1704150 PG 4 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA EW399 UT WOS:A1991EW39900044 PM 1704150 ER PT J AU BRYAN, RT STOKES, SL SPENCER, HC AF BRYAN, RT STOKES, SL SPENCER, HC TI EXPATRIATES TREATED WITH IVERMECTIN SO LANCET LA English DT Letter C1 CTR DIS CONTROL,CTR INFECT DIS,DIV IMMUNOL ONCOL & HEMATOL DIS,ATLANTA,GA 30333. RP BRYAN, RT (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,PARASIT DIS BRANCH,ATLANTA,GA 30333, USA. NR 3 TC 6 Z9 6 U1 0 U2 0 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD FEB 2 PY 1991 VL 337 IS 8736 BP 304 EP 305 DI 10.1016/0140-6736(91)90918-F PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA EV719 UT WOS:A1991EV71900048 PM 1671142 ER PT J AU BRANCHE, CM SNIEZEK, JE SATTIN, RW MIRKIN, IR AF BRANCHE, CM SNIEZEK, JE SATTIN, RW MIRKIN, IR TI WATER RECREATION-RELATED SPINAL-INJURIES - RISK-FACTORS IN NATURAL BODIES OF WATER SO ACCIDENT ANALYSIS AND PREVENTION LA English DT Article C1 US DEPT HHS,PUBL HLTH SERV,CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,DIV FIELD SERV,ATLANTA,GA 30333. RP BRANCHE, CM (reprint author), US DEPT HHS,GRAD SCH PUBL HLTH,CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333, USA. NR 17 TC 16 Z9 17 U1 1 U2 2 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0001-4575 J9 ACCIDENT ANAL PREV JI Accid. Anal. Prev. PD FEB PY 1991 VL 23 IS 1 BP 13 EP 17 DI 10.1016/0001-4575(91)90030-9 PG 5 WC Ergonomics; Public, Environmental & Occupational Health; Social Sciences, Interdisciplinary; Transportation SC Engineering; Public, Environmental & Occupational Health; Social Sciences - Other Topics; Transportation GA EY987 UT WOS:A1991EY98700002 PM 2021399 ER PT J AU BUTERA, S PEREZ, VL NABEL, GJ FOLKS, TM AF BUTERA, S PEREZ, VL NABEL, GJ FOLKS, TM TI HIV-1 ACTIVATION IN AN INFECTED PROMYELOCYTIC CELL CLONE SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Meeting Abstract C1 CTR DIS CONTROL,RETROVIRUS DIS BRANCH,ATLANTA,GA 30333. UNIV MICHIGAN,MED CTR,HOWARD HUGHES MED INST,ANN ARBOR,MI 48109. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PD FEB PY 1991 VL 7 IS 2 BP 208 EP 209 PG 2 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA EY300 UT WOS:A1991EY30000153 ER PT J AU FRIEDMANKIEN, AE SALTZMAN, BR HUANG, YQ PETERMAN, T LI, JJ AF FRIEDMANKIEN, AE SALTZMAN, BR HUANG, YQ PETERMAN, T LI, JJ TI KAPOSIS-SARCOMA IN HIV UNINFECTED HOMOSEXUAL OR BISEXUAL MEN SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Meeting Abstract C1 NYU MED CTR,NEW YORK,NY 10016. BETH ISRAEL MED CTR,NEW YORK,NY 10003. CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PD FEB PY 1991 VL 7 IS 2 BP 221 EP 221 PG 1 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA EY300 UT WOS:A1991EY30000175 ER PT J AU LEVINE, PH WIKTOR, S JACOBSON, S COLCLOUGH, G KAPLAN, J LAIRMORE, M BLATTNER, WA AF LEVINE, PH WIKTOR, S JACOBSON, S COLCLOUGH, G KAPLAN, J LAIRMORE, M BLATTNER, WA TI HTLV-I/II INFECTION IN WESTERN-HEMISPHERE NATIVE-AMERICANS SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Meeting Abstract C1 NIH,BETHESDA,MD 20892. RES TRIANGLE INST,WASHINGTON,DC. CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 1 Z9 1 U1 0 U2 0 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PD FEB PY 1991 VL 7 IS 2 BP 237 EP 238 PG 2 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA EY300 UT WOS:A1991EY30000204 ER PT J AU CROUCH, KG PENG, TY MURDOCK, DJ AF CROUCH, KG PENG, TY MURDOCK, DJ TI VENTILATION CONTROL OF LEAD IN INDOOR FIRING RANGES - INLET CONFIGURATION AND BOOTH AND FLUCTUATING FLOW CONTRIBUTIONS SO AMERICAN INDUSTRIAL HYGIENE ASSOCIATION JOURNAL LA English DT Article AB Workers in and, in some cases, users of indoor firing ranges continue to receive overexposures to airborne lead levels in spite of efforts to produce smooth and ample ventilation. Studies of firing ranges by researchers for the National Institute for Occupational Safety and Health (NIOSH) and others have shown that only on very infrequent occasions will the ventilation airflow adequately control lead exposures. Some firing ranges use only ventilation to control lead exposures, and these have stimulated a search for the ventilation system elements that will ensure successful control. Substitution of nonlead bullets and primer as a control means has shown some success but has not gained widespread acceptance because of its effects on the accuracy, range, and reliability of firearms. Several approaches leading to adequate ventilation control of lead in indoor firing ranges were investigated. Observations of flow patterns in firing ranges led to an investigation of the firing range air inlet as the primary source of backflow and eddy formation causing elevated lead exposures. Work on a full-scale model firing range shows that backflow can be suppressed in several cases by the use of a double pegboard at the inlet. In addition, a dual inlet with flow alternating between inlets effectively eliminates eddy and wake formation. Flow patterns resulting from various inlet configurations were observed during smoke release studies. Systems that produced a flow pattern free of backflow over potentially occupied regions of the model firing range, as shown by the smoke release studies, were further investigated by measurements of velocity and turbulence intensity profiles. further research will involve incorporating these controls in actual firing ranges as confirmation of their adequacy. Smoke release studies also were used in the model firing range to determine the effects of the shooter's booth on airflow at the firing line. Quantitative measurements of relative exposure for a mannequin simulating a shooter were made using smoke release. A smoke concentration measurement was made in the breathing zone by an optical particle detector. Several booth modifications involving slots and fins were shown to reduce exposures. The shooter's wake was shown to be a fundamental element of backflow exposure paths in these booth studies. C1 INST ENVIRONM HLTH & ENGN,BEIJING,PEOPLES R CHINA. RP CROUCH, KG (reprint author), NIOSH,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 13 TC 4 Z9 4 U1 1 U2 3 PU AMER INDUSTRIAL HYGIENE ASSOC PI FAIRFAX PA 2700 PROSPERITY AVE #250, FAIRFAX, VA 22031-4307 SN 0002-8894 J9 AM IND HYG ASSOC J JI Am. Ind. Hyg. Assoc. J. PD FEB PY 1991 VL 52 IS 2 BP 81 EP 91 DI 10.1202/0002-8894(1991)052<0081:VCOLII>2.0.CO;2 PG 11 WC Environmental Sciences; Public, Environmental & Occupational Health SC Environmental Sciences & Ecology; Public, Environmental & Occupational Health GA EW755 UT WOS:A1991EW75500008 ER PT J AU STEENLAND, K BEAUMONT, J ELLIOT, L AF STEENLAND, K BEAUMONT, J ELLIOT, L TI LUNG-CANCER IN MILD-STEEL WELDERS SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Article DE LUNG NEOPLASMS; OCCUPATIONS; WELDING ID SMOKING; COHORT; MORTALITY; MODELS; RATIOS AB To investigate lung cancer risk, the authors conducted a historical cohort mortality study of 4,459 mild steel welders who had been employed at three midwestern plants which manufactured heavy equipment. Follow-up began in the mid-1950s and extended through 1988. All welders had at least 2 years welding experience (average duration, 8.5 years). This cohort had no occupational exposure to asbestos or stainless steel fumes (containing nickel and chromium), two potential confounders in previous welders studies. A comparison population of 4,286 nonwelders, all with at least 2 years employment at the same plants, was also studied. Nonwelders had never been welders and were allowed to have no more than 90 days employment as a painter, foundryman, or machinist. Sampling data collected from 1974-1987 indicated that welders were exposed to 6-7 mg/m3 of total particulate and 3-4 mg/m3 of iron oxide, while nonwelders had negligible exposures to welding fumes. When compared with the United States population, both welders and nonwelders had elevated rates for lung cancer (standardized mortality ratios (SMRs): welders, SMR = 1.07; nonwelders, SMR = 1.17), but neither SMR was significantly elevated. Limited smoking data based on a 1985 survey indicated that both welders and nonwelders smoked more than the United States population, possibly accounting for part of their elevated lung cancer rates. There was no trend of increased risk for welders with increased duration of exposure. The only other cause of death significantly elevated was emphysema among welders. Nonmalignant respiratory disease was not elevated for welders (SMR = 0.96). When welders were compared with nonwelders directly for lung cancer, the rate ratio was 0.90. C1 UNIV CALIF DAVIS,DAVIS,CA 95616. RP STEENLAND, K (reprint author), NIOSH,4676 COLUMBIA PKWY,R-13,CINCINNATI,OH 45226, USA. NR 21 TC 33 Z9 34 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD FEB 1 PY 1991 VL 133 IS 3 BP 220 EP 229 PG 10 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EY297 UT WOS:A1991EY29700002 PM 2000839 ER PT J AU MORRIS, PD LENHART, SW SERVICE, WS AF MORRIS, PD LENHART, SW SERVICE, WS TI RESPIRATORY SYMPTOMS AND PULMONARY-FUNCTION IN CHICKEN CATCHERS IN POULTRY CONFINEMENT UNITS SO AMERICAN JOURNAL OF INDUSTRIAL MEDICINE LA English DT Article DE RESPIRATORY DYSFUNCTION; CHRONIC BRONCHITIS; PULMONARY FUNCTION TESTS; RESPIRATORY TOXICANTS; ORGANIC DUST; ENDOTOXINS; AMMONIA ID BLUE-COLLAR WORKERS; DUST AB To evaluate the respiratory consequences of working in poultry confinement units, we completed a cross-sectional epidemiologic study of respiratory symptoms and pulmonary function in 59 chicken catchers. The results were compared to a published reference standard of noneexposed blue-collar workers. Chicken catchers reported a high rate of acute symptoms associated with work in poultry houses. They also reported statistically significant higher rates for chronic phelgm (39.0%) and chronic wheezing (27.1%) than nonexposed blue-collar workers. Chicken catchers had significant decrements over a work shift in forced vital capacity (-2.2%) and forced expiratory volume in 1 sec (-3.4%), and there was suggestive evidence that they had decreased preshift pulmonary function compared with nonexposed blue-collar workers. These results indicate that chicken catchers are at risk for respiratory dysfunction and emphasize the need to develop measures to minimize their exposure to respiratory toxicants in poultry confinement units. C1 CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,DIV FIELD SERV,ATLANTA,GA 30333. RP MORRIS, PD (reprint author), DEPT ENVIRONM HLTH & NAT RESOURCES,DIV EPIDEMIOL,ENVIRONM EPIDEMIOL SECT,POB 27687,RALEIGH,NC 27611, USA. NR 24 TC 34 Z9 34 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0271-3586 J9 AM J IND MED JI Am. J. Ind. Med. PD FEB PY 1991 VL 19 IS 2 BP 195 EP 204 DI 10.1002/ajim.4700190207 PG 10 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EP475 UT WOS:A1991EP47500006 PM 1992677 ER PT J AU EMORI, TG CULVER, DH HORAN, TC JARVIS, WR WHITE, JW OLSON, DR BANERJEE, S EDWARDS, JR MARTONE, WJ GAYNES, RP HUGHES, JM AF EMORI, TG CULVER, DH HORAN, TC JARVIS, WR WHITE, JW OLSON, DR BANERJEE, S EDWARDS, JR MARTONE, WJ GAYNES, RP HUGHES, JM TI NATIONAL NOSOCOMIAL INFECTIONS SURVEILLANCE SYSTEM (NNIS) - DESCRIPTION OF SURVEILLANCE METHODS SO AMERICAN JOURNAL OF INFECTION CONTROL LA English DT Article AB The National Nosocomial Infections Surveillance System (NNIS) is an ongoing collaborative surveillance system sponsored by the Centers for Disease Control (CDC) to obtain national data on nosocomial infections. The CDC uses the data that are reported voluntarily by participating hospitals to estimate the magnitude of the nosocomial infection problem in the United States and to monitor trends in infections and risk factors. Hospitals collect data by prospectively monitoring specific groups of patients for infections with the use of protocols called surveillance components. The surveillance components used by the NNIS are hospitalwide, intensive care unit, high-risk nursery, and surgical patient. Detailed information including demographic characteristics, infections and related risk factors, pathogens and their antimicrobial susceptibilities, and outcome, is collected on each infected patient. Data on risk factors in the population of patients being monitored are also collected; these permit the calculation of risk-specific rates. An infection risk index, which includes the traditional wound class, is being evaluated as a predictor of the likelihood that an infection will develop after an operation. A major goal of the NNIS is to use surveillance data to develop and evaluate strategies to prevent and control nosocomial infections. The data collected with the use of the surveillance components permit the calculation of risk-specific infection rates, which can be used by individual hospitals as well as national health-care planners to set priorities for their infection control programs and to evaluate the effectiveness of their efforts. The NNIS will continue to evolve in finding more effective and efficient ways to assess the influence of patient risk and changes in the financing of health care on the infection rate. RP EMORI, TG (reprint author), CTR DIS CONTROL,US PHS,CTR INFECTIOUS DIS,DEPT HLTH & HUMAN SERV,ATLANTA,GA 30333, USA. NR 0 TC 485 Z9 502 U1 1 U2 15 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0196-6553 J9 AM J INFECT CONTROL JI Am. J. Infect. Control PD FEB PY 1991 VL 19 IS 1 BP 19 EP 35 DI 10.1016/0196-6553(91)90157-8 PG 17 WC Public, Environmental & Occupational Health; Infectious Diseases SC Public, Environmental & Occupational Health; Infectious Diseases GA EZ149 UT WOS:A1991EZ14900004 PM 1850582 ER PT J AU SYVERSON, CJ CHAVKIN, W ATRASH, HK ROCHAT, RW SHARP, ES KING, GE AF SYVERSON, CJ CHAVKIN, W ATRASH, HK ROCHAT, RW SHARP, ES KING, GE TI PREGNANCY-RELATED MORTALITY IN NEW-YORK-CITY, 1980 TO 1984 - CAUSES OF DEATH AND ASSOCIATED RISK-FACTORS SO AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY LA English DT Article DE PREGNANCY; EMBOLISM; ECTOPIC PREGNANCY; ANESTHESIA ID MATERNAL MORTALITY; UNITED-STATES AB To identify causes and risk factors for pregnancy-related mortality in New York City, we analyzed 224 pregnancy-related deaths that occurred from 1980 to 1984. The leading causes of death were ectopic pregnancy complications, embolism, intrapartum cardiac arrest, and hypertension. Mortality ratios were determined by comparing the characteristics of the women whose death was pregnancy-related with those of women who had survived delivery of a live infant in New York City during the same period. Black and Hispanic women had mortality ratios that were respectively 4.2 and 2.0 times higher than those for white, non-Hispanic women. In comparison with women aged 20 to 24, those older than 30 were more than twice as likely to die from pregnancy-related causes, and those older than 40 were five times as likely to do so. Other factors that were associated with an increased risk of pregnancy-related mortality included 9 to 11 years of education, lack of private medical insurance, more than five previous pregnancies, and fewer than five prenatal visits. This study suggests that changes in current maternal-health and family-planning services will be required to achieve further reductions in preventable pregnancy-related mortality. C1 CTR DIS CONTROL,DIV REPROD HLTH,1600 CLIFTON RD NE,BLDG 1,ROOM 4409,ATLANTA,GA 30333. EMORY UNIV,SCH MED,DIV GYNECOL & OBSTET,ATLANTA,GA 30322. EMORY UNIV,MASTER PUBL HLTH PROGRAM,ATLANTA,GA 30322. EMORY UNIV,NELL HODGSON WOODRUFF SCH NURSING,ATLANTA,GA 30322. RI Rochat, Roger/J-9802-2012 NR 29 TC 31 Z9 31 U1 0 U2 1 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0002-9378 J9 AM J OBSTET GYNECOL JI Am. J. Obstet. Gynecol. PD FEB PY 1991 VL 164 IS 2 BP 603 EP 608 PG 6 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA EX765 UT WOS:A1991EX76500031 PM 1992710 ER PT J AU SELIGMAN, PJ MATTE, TD AF SELIGMAN, PJ MATTE, TD TI CASE DEFINITIONS IN PUBLIC-HEALTH SO AMERICAN JOURNAL OF PUBLIC HEALTH LA English DT Editorial Material RP SELIGMAN, PJ (reprint author), NIOSH,DIV SURVEILLANCE HAZARD EVALUAT & FIELD STUDIES,CINCINNATI,OH 45226, USA. NR 10 TC 5 Z9 5 U1 0 U2 0 PU AMER PUBLIC HEALTH ASSN INC PI WASHINGTON PA 1015 FIFTEENTH ST NW, WASHINGTON, DC 20005 SN 0090-0036 J9 AM J PUBLIC HEALTH JI Am. J. Public Health PD FEB PY 1991 VL 81 IS 2 BP 161 EP 162 DI 10.2105/AJPH.81.2.161 PG 2 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EY430 UT WOS:A1991EY43000003 PM 1990851 ER PT J AU EBERHARD, ML DICKERSON, JW BOYER, AE TSANG, VCW ZEAFLORES, R WALKER, EM RICHARDS, FO ZEAFLORES, G STROBERT, E AF EBERHARD, ML DICKERSON, JW BOYER, AE TSANG, VCW ZEAFLORES, R WALKER, EM RICHARDS, FO ZEAFLORES, G STROBERT, E TI EXPERIMENTAL ONCHOCERCA-VOLVULUS INFECTIONS IN MANGABEY MONKEYS (CERCOCEBUS-ATYS) COMPARED TO INFECTIONS IN HUMAN AND CHIMPANZEES (PAN-TROGLODYTES) SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID MERIONES-UNGUICULATUS; MANSONELLA-OZZARDI; SKIN SNIPS; LOA-LOA; JIRD; PRIMATES; MICROFILARIAE; ANTIBODIES; ANTIGENS; RODENTS AB Three chimpanzees, three mangabey monkeys (Cercocebus atys), and 14 patas monkeys (Erythrocebus patas) were inoculated with L3 Onchocerca volvulus of Guatemalan origin. One chimpanzee and two mangabey monkeys developed antibody activity to at least three different antigens. Both mangabey monkeys recognized a 20 kDa antigen 3.5-5 months post-inoculation, and the monkeys and the chimpanzee developed antibody activity to 14 and 22 kDa antigens 7.5-13 months post-inoculation. One mangabey monkey and the chimpanzee became microfilaria-positive in skin snips at 16 and 21 months post-inoculation, respectively. Antibody activity to the 20 kDa antigen in the mangabey monkeys is noteworthy because of the prominence of this antigen among putatively immune persons living in onchocerciasis-endemic areas. The two mangabey monkeys responded parasitologically in a manner comparable to immune humans. No microfilariae were detected in one monkey and only scant numbers of microfilariae were observed in the second. The mangabey monkey may be a good animal model for the study of onchocerciasis. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,ATLANTA,GA 30333. UNIV VALLE,CTR INVEST ENFERMEDADES TROP,GUATEMALA CITY,GUATEMALA. MINIST HLTH,GUATEMALA CITY,GUATEMALA. EMORY UNIV,YERKES REG PRIMATE RES CTR,ATLANTA,GA 30322. FU NCRR NIH HHS [RR00165] NR 29 TC 19 Z9 20 U1 0 U2 0 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD FEB PY 1991 VL 44 IS 2 BP 151 EP 160 PG 10 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA FF797 UT WOS:A1991FF79700007 PM 2012258 ER PT J AU HITCH, WL HIGHTOWER, AW EBERHARD, ML LAMMIE, PJ AF HITCH, WL HIGHTOWER, AW EBERHARD, ML LAMMIE, PJ TI ANALYSIS OF ISOTYPE-SPECIFIC ANTIFILARIAL ANTIBODY-LEVELS IN A HAITIAN PEDIATRIC POPULATION SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID HUMAN IMMUNODEFICIENCY VIRUS; HUMAN FILARIASIS; BRUGIA-PAHANGI; PHOSPHORYLCHOLINE; RESPONSES; INFECTION; ANTIGENS; PARASITE; LARVAE; ASSAY AB Previous studies of antifilarial antibodies in a pediatric population residing in an area with endemic Wuchereria bancrofti filariasis have demonstrated age related shifts in antifilarial immunity. To further characterize humoral responses in Haitian children, serum samples from 129 patients (3 months-15 years of age) were analyzed by ELISA for isotype-specific antifilarial antibody responses. Age-stratified analysis of geometric mean antibody titers showed significant increases in antibody titers of all isotypes with age in the amicrofilaremic population. Antifilarial IgG1, 2, and 3 levels were higher in amicrofilaremic children than in microfilaremic children, significantly so for IgG2 and IgG3. In contrast, IgG4 antibody levels were higher in microfilaremic subjects than in amicrofilaremic subjects. A multivariate, unconditional, logistic regression model was developed from these data to predict infection status. The model correctly classified 91.6% of the amicrofilaremic subjects, but only 55.6% of the microfilaremic subjects. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,ATLANTA,GA 30333. RP HITCH, WL (reprint author), EMORY UNIV,ATLANTA,GA 30322, USA. FU NIAID NIH HHS [AI-02642, AI-16315]; PHS HHS [YO2-0005-01] NR 20 TC 42 Z9 42 U1 0 U2 0 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD FEB PY 1991 VL 44 IS 2 BP 161 EP 167 PG 7 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA FF797 UT WOS:A1991FF79700008 PM 2012259 ER PT J AU NEILL, MA OPAL, SM HEELAN, J GIUSTI, R CASSIDY, JE WHITE, R MAYER, KH AF NEILL, MA OPAL, SM HEELAN, J GIUSTI, R CASSIDY, JE WHITE, R MAYER, KH TI FAILURE OF CIPROFLOXACIN TO ERADICATE CONVALESCENT FECAL EXCRETION AFTER ACUTE SALMONELLOSIS - EXPERIENCE DURING AN OUTBREAK IN HEALTH-CARE WORKERS SO ANNALS OF INTERNAL MEDICINE LA English DT Article ID RESISTANT SALMONELLA; BACTERIAL DIARRHEA; CLINICAL EFFICACY; INFECTION; PLACEBO AB Objective: To determine the efficacy of ciprofloxacin therapy in eradicating convalescent fecal excretion of salmonellae after acute salmonellosis. Design: Randomized, placebo-controlled, double-blind trial of ciprofloxacin, with prospective follow-up of nonparticipants. Setting: An acute care community hospital experiencing an outbreak of salmonellosis. Patients: Twenty-eight health care workers developed acute infection with Salmonella java; 15 participated in a placebocontrolled trial of ciprofloxacin, beginning on day 9 after infection. Interventions: Eight patients were randomly assigned to receive ciprofloxacin, 750 mg, and 7 patients to receive placebo; both were administered orally twice daily for 14 days. Nonparticipants who received therapy were placed on the same ciprofloxacin regimen. Measurements and Main Results: Study participants had follow-up stool cultures every 3 days initially and then weekly for 3 weeks; nonparticipants were followed until three consecutive cultures were negative. All eight ciprofloxacin recipients showed eradication of S.java from stool cultures within 7 days of beginning therapy (compared with 1 of 7 placebo recipients), and their stool cultures remained negative up to 14 days after discontinuing therapy (P < 0.01). However, 4 of 8 relapsed; their stool cultures became positive between 14 and 21 days after therapy. In addition, 3 of 3 hospitalized patients treated with ciprofloxacin who did not participate in the controlled trial also relapsed. Thus, the total relapse rate was 7 of 11 (64%; 95% CI, 31% to 89%). In 4 of these 7 patients, relapse was associated with a longer duration of fecal excretion of salmonellae than that of the placebo group. Relapse could not be explained on the basis of noncompliance, development of resistance, or presence of biliary disease. Conclusions: Despite its excellent antimicrobial activity against salmonellae and its favorable pharmacokinetic profile, ciprofloxacin at a dosage of 750 mg orally twice daily had an unacceptably high failure rate in patients with acute salmonellosis and may have prolonged fecal excretion of salmonellae. The late occurrence of relapses indicates the need to obtain stool cultures up to 21 days after therapy to document fecal eradication in acute salmonellosis. C1 BROWN UNIV,PROGRAM MED,PROVIDENCE,RI 02912. US DEPT HLTH,PROVIDENCE,RI. CTR DIS CONTROL,ATLANTA,GA 30333. RP NEILL, MA (reprint author), MEM HOSP,DIV INFECT DIS,111 BREWSTER ST,PAWTUCKET,RI 02860, USA. NR 27 TC 100 Z9 102 U1 0 U2 0 PU AMER COLL PHYSICIANS PI PHILADELPHIA PA INDEPENDENCE MALL WEST 6TH AND RACE ST, PHILADELPHIA, PA 19106-1572 SN 0003-4819 J9 ANN INTERN MED JI Ann. Intern. Med. PD FEB 1 PY 1991 VL 114 IS 3 BP 195 EP 199 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA EV339 UT WOS:A1991EV33900004 PM 1898630 ER PT J AU RICE, EW ALLEN, MJ BRENNER, DJ EDBERG, SC AF RICE, EW ALLEN, MJ BRENNER, DJ EDBERG, SC TI ASSAY FOR BETA-GLUCURONIDASE IN SPECIES OF THE GENUS ESCHERICHIA AND ITS APPLICATIONS FOR DRINKING-WATER ANALYSIS SO APPLIED AND ENVIRONMENTAL MICROBIOLOGY LA English DT Note ID NATIONAL FIELD-EVALUATION; DEFINED SUBSTRATE METHOD; CLINICAL SPECIMENS; TOTAL COLIFORMS; ENTEROBACTERIACEAE; COLI; BIOGROUPS AB Recently, Escherichia species other than Escherichia coli have been isolated from potable water. Environmental isolates as well as clinical isolates of E. adecarboxylata, E. blattae, E. fergusonii, E. hermannii, and E. vulneris were assayed for the enzyme beta-glucuronidase by using EC MUG medium and the Colilert system. None of the isolates were positive for the enzyme by either method. C1 AMER WATER WORKS ASSOC RES FDN,DENVER,CO 80235. YALE UNIV,SCH MED,NEW HAVEN,CT 06510. CTR DIS CONTROL,ATLANTA,GA 30333. RP RICE, EW (reprint author), US EPA,CINCINNATI,OH 45268, USA. NR 14 TC 48 Z9 48 U1 0 U2 2 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0099-2240 J9 APPL ENVIRON MICROB JI Appl. Environ. Microbiol. PD FEB PY 1991 VL 57 IS 2 BP 592 EP 593 PG 2 WC Biotechnology & Applied Microbiology; Microbiology SC Biotechnology & Applied Microbiology; Microbiology GA EV647 UT WOS:A1991EV64700041 PM 2014993 ER PT J AU FREEDMAN, DS OBRIEN, TR FLANDERS, WD DESTEFANO, F BARBORIAK, JJ AF FREEDMAN, DS OBRIEN, TR FLANDERS, WD DESTEFANO, F BARBORIAK, JJ TI RELATIONSHIP OF SERUM TESTOSTERONE LEVELS TO HIGH-DENSITY-LIPOPROTEIN CHOLESTEROL AND OTHER CHARACTERISTICS IN MEN SO CIRCULATION LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER HEART ASSOC PI DALLAS PA 7272 GREENVILLE AVENUE, DALLAS, TX 75231-4596 SN 0009-7322 J9 CIRCULATION JI Circulation PD FEB PY 1991 VL 83 IS 2 BP 718 EP 718 PG 1 WC Cardiac & Cardiovascular Systems; Peripheral Vascular Disease SC Cardiovascular System & Cardiology GA EW940 UT WOS:A1991EW94000055 ER PT J AU ANDA, RF JONES, DH MACERA, CA WILLIAMSON, DF EAKER, ED MARKS, JS AF ANDA, RF JONES, DH MACERA, CA WILLIAMSON, DF EAKER, ED MARKS, JS TI HOPELESSNESS AND MORTALITY FROM ISCHEMIC-HEART-DISEASE IN THE NHANES-I EPIDEMIOLOGIC FOLLOW-UP-STUDY SO CIRCULATION LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 4 Z9 4 U1 0 U2 0 PU AMER HEART ASSOC PI DALLAS PA 7272 GREENVILLE AVENUE, DALLAS, TX 75231-4596 SN 0009-7322 J9 CIRCULATION JI Circulation PD FEB PY 1991 VL 83 IS 2 BP 721 EP 721 PG 1 WC Cardiac & Cardiovascular Systems; Peripheral Vascular Disease SC Cardiovascular System & Cardiology GA EW940 UT WOS:A1991EW94000069 ER PT J AU JONES, DH FORD, E AF JONES, DH FORD, E TI CARDIOVASCULAR HEALTH KNOWLEDGE IN THE UNITED-STATES - NATIONAL ESTIMATES FROM NHIS, 1985 SO CIRCULATION LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 2 PU AMER HEART ASSOC PI DALLAS PA 7272 GREENVILLE AVENUE, DALLAS, TX 75231-4596 SN 0009-7322 J9 CIRCULATION JI Circulation PD FEB PY 1991 VL 83 IS 2 BP 730 EP 730 PG 1 WC Cardiac & Cardiovascular Systems; Peripheral Vascular Disease SC Cardiovascular System & Cardiology GA EW940 UT WOS:A1991EW94000106 ER PT J AU MUELLER, PW MACNEIL, ML SMITH, SJ MILLER, DT AF MUELLER, PW MACNEIL, ML SMITH, SJ MILLER, DT TI INTERLABORATORY COMPARISON OF THE MEASUREMENT OF ALBUMIN IN URINE SO CLINICAL CHEMISTRY LA English DT Article DE VARIATION, SOURCE OF; ASSESSING RENAL FUNCTION; ENZYME IMMUNOASSAY; FLUOROIMMUNOASSAY; IMMUNOTURBIDIMETRY; ZONE IMMUNOELECTROPHORESIS ID DIABETIC NEPHROPATHY; RENAL-FUNCTION; CADMIUM; IMMUNOASSAY; EXCRETION; MICROALBUMINURIA; KIDNEY; PROTEINURIA; VARIABILITY; MORTALITY AB Because of increased interest in the assay of albumin in urine and the sensitivity required to quantify concentrations associated with (a) increased risk of developing end-stage renal disease and cardiovascular disease among people with diabetes and (b) renal damage caused by exposure to nephrotoxic substances, we conducted a pilot study of the variation of these measurements within and among five laboratories that use various immunoassays. These assays included two different enzyme immunoassays, two different immunoturbidimetric assays, a fluorescent immunoassay, and a zone immunoelectrophoresis assay. The results indicate considerable variation both within and among laboratories for measurements at or near the normal range. Variability is equally attributable to the precision of individual immunoassays and to the variation of the mean values obtained by each laboratory. Individual laboratory CVs ranged from 5.8% to 18.2% for mid- and high-concentration samples treated with preservative and from 8.4% to 23.6% for mid- and high-concentration samples containing no preservative. The relative bias of individual laboratory means ranged from -56.4% to 20.5% for the two preserved materials and from -32.6% to 0.8% for the two materials containing no preservative. To reduce the chance of misdiagnosing the risk associated with above-normal albumin concentrations in urine, we need to address the problems contributing to imprecision and inaccuracy, particularly laboratory-to-laboratory variability. RP MUELLER, PW (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV ENVIRONM HLTH LAB SCI,ATLANTA,GA 30333, USA. NR 39 TC 14 Z9 15 U1 0 U2 0 PU AMER ASSOC CLINICAL CHEMISTRY PI WASHINGTON PA 2101 L STREET NW, SUITE 202, WASHINGTON, DC 20037-1526 SN 0009-9147 J9 CLIN CHEM JI Clin. Chem. PD FEB PY 1991 VL 37 IS 2 BP 191 EP 195 PG 5 WC Medical Laboratory Technology SC Medical Laboratory Technology GA EY835 UT WOS:A1991EY83500012 PM 1993322 ER PT J AU DOLAN, TA GOOCH, BF BOURQUE, LB AF DOLAN, TA GOOCH, BF BOURQUE, LB TI ASSOCIATIONS OF SELF-REPORTED DENTAL-HEALTH AND GENERAL HEALTH MEASURES IN THE RAND HEALTH-INSURANCE EXPERIMENT SO COMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY LA English DT Article DE DENTAL HEALTH SURVEYS; HEALTH STATUS INDICATORS; ORAL HEALTH; SELF-ASSESSMENT (PSYCHOLOGY) ID SICKNESS IMPACT PROFILE; SOCIODENTAL INDICATORS; MEASUREMENT SCALES; ORAL HEALTH; QUALITY; LIFE; FORMULATION; ARTHRITIS; DISEASE; TRIAL AB Data from the Rand Health Insurance Experiment (HIE) are used in exploratory analyses to examine the associations of self-reported dental health with general health measures. Responses of 1658 dentulous participants 18-61 yr of age are examined. Patterns of association among and between items of the physical, mental, social, and general health indices and a three-item measure of self-reported dental health are tested using principal component analyses. Findings suggest that dental health represents a separate dimension of health that is not fully accounted for by other health measures. However, while dental health may be considered an independent health construct, the dental health index was weakly but statistically significantly associated with the general health perceptions index and, to a lesser extent, to the mental health index and the two physical health indices. Improved self-reported measures of dental health status, studied in association with other general health measures, will allow us to better define oral health, and patients' perceptions of oral health, particularly in relation to other general health perceptions. In addition, a valid and reliable multidimensional oral health measure would be valuable as a potential cost-effective method of epidemiologic data collection, as well as a tool for evaluating the effectiveness of oral health interventions, and for providing data for dental health policy making and planning. C1 CTR DIS CONTROL,ATLANTA,GA 30333. UNIV CALIF LOS ANGELES,SCH PUBL HLTH,LOS ANGELES,CA 90024. RP DOLAN, TA (reprint author), UNIV FLORIDA,J HILLIS MILLER HLTH CTR,COLL DENT,BOX J-404,GAINESVILLE,FL 32610, USA. NR 37 TC 28 Z9 29 U1 3 U2 4 PU MUNKSGAARD INT PUBL LTD PI COPENHAGEN PA 35 NORRE SOGADE, PO BOX 2148, DK-1016 COPENHAGEN, DENMARK SN 0301-5661 J9 COMMUNITY DENT ORAL JI Community Dentist. Oral Epidemiol. PD FEB PY 1991 VL 19 IS 1 BP 1 EP 8 DI 10.1111/j.1600-0528.1991.tb00095.x PG 8 WC Dentistry, Oral Surgery & Medicine; Public, Environmental & Occupational Health SC Dentistry, Oral Surgery & Medicine; Public, Environmental & Occupational Health GA EZ268 UT WOS:A1991EZ26800001 PM 2019082 ER PT J AU DUNN, RA ROLFS, RT AF DUNN, RA ROLFS, RT TI THE RESURGENCE OF SYPHILIS IN THE UNITED-STATES SO CURRENT OPINION IN INFECTIOUS DISEASES LA English DT Article AB More cases of primary and secondary syphilis were reported in 1989 than in any year since 1949. Incidence is rising despite four decades of penicillin therapy. The spread of syphilis has been linked to the rising incidence of drug use, especially of crack cocaine. Observations in patients coinfected with human immunodeficiency virus have raised questions about the adequacy of penicillin and prompted a reevaluation of syphilis therapy. Efforts to control the epidemic have brought needed attention to improving health care delivery to persons at risk for syphilis. RP DUNN, RA (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,DIV SEXUALLY TRANSMITTED DIS HIV PREVENT,MAIL STOP E02,ATLANTA,GA 30333, USA. NR 0 TC 13 Z9 13 U1 0 U2 0 PU CURRENT SCIENCE PI PHILADELPHIA PA 400 MARKET STREET,SUITE 750 ATTN:SARAH WHEALEN/SUB MGR, PHILADELPHIA, PA 19106 SN 0951-7375 J9 CURR OPIN INFECT DIS JI Curr. Opin. Infect. Dis. PD FEB PY 1991 VL 4 IS 1 BP 3 EP 11 DI 10.1097/00001432-199102000-00002 PG 9 WC Infectious Diseases SC Infectious Diseases GA FE831 UT WOS:A1991FE83100002 ER PT J AU EKBOM, A HELMICK, C ZACK, M ADAMI, HO AF EKBOM, A HELMICK, C ZACK, M ADAMI, HO TI THE EPIDEMIOLOGY OF INFLAMMATORY BOWEL-DISEASE - A LARGE, POPULATION-BASED STUDY IN SWEDEN SO GASTROENTEROLOGY LA English DT Article ID CROHNS-DISEASE; ULCERATIVE-COLITIS; JEWISH POPULATION; DEFINED POPULATION; OLMSTED COUNTY; PREVALENCE; MINNESOTA; CARDIFF; PROCTOCOLITIS; NETHERLANDS C1 CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,ATLANTA,GA 30333. RP EKBOM, A (reprint author), UNIV HOSP UPPSALA,DEPT SURG,S-75185 UPPSALA,SWEDEN. NR 40 TC 312 Z9 325 U1 0 U2 7 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0016-5085 J9 GASTROENTEROLOGY JI Gastroenterology PD FEB PY 1991 VL 100 IS 2 BP 350 EP 358 PG 9 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA ER722 UT WOS:A1991ER72200008 PM 1985033 ER PT J AU JANDA, RC CONKLIN, JL MITROS, FA PARSONNET, J AF JANDA, RC CONKLIN, JL MITROS, FA PARSONNET, J TI MULTIFOCAL COLITIS ASSOCIATED WITH AN EPIDEMIC OF CHRONIC DIARRHEA SO GASTROENTEROLOGY LA English DT Article ID COLLAGENOUS COLITIS; INFECTION C1 UNIV IOWA,COLL MED,DEPT INTERNAL MED,DIV GASTROENTEROL HEPATOL,IOWA CITY,IA 52242. UNIV IOWA,COLL MED,DEPT PATHOL,IOWA CITY,IA 52242. CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,DIV ENTER DIS,ATLANTA,GA 30333. FU NIDDK NIH HHS [DK01750] NR 9 TC 13 Z9 13 U1 0 U2 0 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0016-5085 J9 GASTROENTEROLOGY JI Gastroenterology PD FEB PY 1991 VL 100 IS 2 BP 458 EP 464 PG 7 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA ER722 UT WOS:A1991ER72200022 PM 1985042 ER PT J AU HODGE, TW SASSO, DR MCDOUGAL, JS AF HODGE, TW SASSO, DR MCDOUGAL, JS TI HUMANS WITH OKT4-EPITOPE DEFICIENCY HAVE A SINGLE NUCLEOTIDE BASE CHANGE IN THE CD4 GENE, RESULTING IN SUBSTITUTION OF TRP240 FOR ARG240 SO HUMAN IMMUNOLOGY LA English DT Article ID SYSTEMIC LUPUS-ERYTHEMATOSUS; INDUCER T-CELLS; MONOCLONAL-ANTIBODIES; DIFFERENTIATION ANTIGEN; EPITOPE DEFICIENCY; OKT4 EPITOPE; BINDING; HIV; LYMPHOCYTES; SITE AB The OKT4 epitope of the CD4 cell-surface protein has been shown to be polymorphic in white, black, and Japanese populations. The variable phenotypic expression is due to an alteration of the OKT4 epitope, since those persons lacking reactivity with OKT4 monoclonal antibody (mAb) are reactive with OKT4A-F mAb as well as other mAb specific for CD4. To determine the nature of this polymorphism at the gene level, we sequenced polymerase chain reaction-amplified genomic DNA containing the CD4-V3 and -V4 exons from American black subjects who are OKT4-normal, OKT4-negative heterozygous, or OKT4-negative homozygous. Comparison of the sequences revealed that the two CD4 exons are identical except for a cytosine-to-thymidine transition occurring at nucleotide position 868. This alters the first codon position of mino acid 240 and results in a tryptophan residue replacing an arginine residue. The change was also found in white and Japanese persons who are OKT4-negative. RP HODGE, TW (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV IMMUNOL HEMATOL & ONCOL DIS,IMMUNOL BRANCH,BLDG 1,ROOM 1226,ATLANTA,GA 30333, USA. NR 32 TC 22 Z9 23 U1 0 U2 1 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0198-8859 J9 HUM IMMUNOL JI Hum. Immunol. PD FEB PY 1991 VL 30 IS 2 BP 99 EP 104 DI 10.1016/0198-8859(91)90077-M PG 6 WC Immunology SC Immunology GA EW498 UT WOS:A1991EW49800004 PM 1708753 ER PT J AU LIU, H ALDER, JD STEINER, BM STEINSTREILEIN, J LIM, L SCHELL, RF AF LIU, H ALDER, JD STEINER, BM STEINSTREILEIN, J LIM, L SCHELL, RF TI ROLE OF L3T4+ AND 38+ T-CELL SUBSETS IN RESISTANCE AGAINST INFECTION WITH TREPONEMA-PALLIDUM SUBSP PERTENUE IN HAMSTERS SO INFECTION AND IMMUNITY LA English DT Article ID MONOCLONAL-ANTIBODIES; MYCOBACTERIUM-TUBERCULOSIS; SYPHILITIC LESIONS; FLOW-CYTOMETRY; LYT-2+ CELLS; MACROPHAGES; PHAGOCYTOSIS; IMMUNITY; INTERFERON; RABBITS AB The protective immunity conferred by T-cell subsets against infection with Treponema pallidum subsp. pertenue was studied. We demonstrated that hamster T cells can be separated into two subsets by monoclonal antibody (MAb) GK 1.5(anti-L3T4) and MAb 38. Eighty-five percent of hamster thymocytes were L3T4+ 87% were 38+ cells; 84% were dual positive for MAbs anti-L3T4 and 38. In the peripheral lymph nodes, however, the L3T4+ and 38+ T cells were mutually exclusive according to two-color immunofluorescence analysis. The two T-cell subsets were found to be functionally distinct according to their secretion of interleukin 2 (IL-2) when stimulated with concanavalin A. The L3T4+ cells secreted IL-2 and had characteristics of T helper cells, while the 38+ cells did not secrete IL-2 and appeared to be T cytotoxic-suppressor cells. Transfer of 4 x 10(6) helper or cytotoxic-suppressor T lymphocytes from T. pallidum subsp. pertenue-immune hamsters protected irradiated naive hamsters against challenge with this subspecies. IL-2 production could still be detected in the irradiated recipients 12 days after irradiation of naive recipients, although at a low level. This suggests that the remaining lymph node cells could support the survival and expansion of the infused cytotoxic-suppressor T cells. No accumulation of macrophages was observed in regional lymph nodes of immune T-cell recipients within 10 days of infection. Instead, there was an influx of polymorphonuclear neutrophils in all animals injected with T. pallidum subsp. pertenue. This report demonstrates that hamster T cells can be separated into two phenotypically and functionally distinct subsets and that both T-cell subsets confer protection against challenge with T. pallidum subsp. pertenue. C1 UNIV WISCONSIN,DEPT MED MICROBIOL & IMMUNOL,MADISON,WI 53706. UNIV WISCONSIN,WISCONSIN STATE LAB HYG,MADISON,WI 53706. CTR DIS CONTROL,ATLANTA,GA 30341. UNIV MIAMI,DEPT MED,MIAMI,FL 33101. FU NIAID NIH HHS [AI-22199] NR 39 TC 12 Z9 12 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0019-9567 J9 INFECT IMMUN JI Infect. Immun. PD FEB PY 1991 VL 59 IS 2 BP 529 EP 536 PG 8 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA EU973 UT WOS:A1991EU97300009 PM 1987070 ER PT J AU BIAGINI, RE CLARK, JC MOORMAN, WJ KNECHT, EA AF BIAGINI, RE CLARK, JC MOORMAN, WJ KNECHT, EA TI EVALUATION OF THE ONSET AND DURATION OF RESPONSE TO COLD AIR INHALATION CHALLENGE IN CYNOMOLGUS MONKEYS (MACACA-FASCICULARIS) SO JOURNAL OF APPLIED TOXICOLOGY LA English DT Article ID EXERCISE-INDUCED ASTHMA; DISODIUM HEXACHLOROPLATINATE; BRONCHIAL RESPONSIVENESS; IMMUNE-RESPONSES; SMOOTH-MUSCLE; METHACHOLINE; HYPERVENTILATION; TEMPERATURE; HISTAMINE; MECHANISMS AB Cold air inhalation challenge (CAIC) for the evaluation of bronchial reactivity of bronchial reactivity has been proposed as a physical agent alternative to chemical agent challenges (Methacholine or histamine), especially suitable for the occupational environment. The present investigation describes and evaluates a method for performing cold air inhalation challenge in Cynomologus monkeys (macaca fascicularis), a species shown to be useful in animal modeling studies of occupational asthma. Six adult male anesthetized monkeys were ventilated by changes in external pressure while breathing cold air (-25-degrees-C to -30-degrees-C). Pulmonary function testing was performed at 10, 25, 40 and 55 min post-challenge. Significant increases (P < 0.05) in average pulmonary flow resistance (R(L)) and decreases in dynamic compliance (C(L dyn)) were observed, with maximum impairment occurring at 25 min post-challenge, with a trend towards a return to baseline values at 55 min post-challenge. Peak expiratory flow rate (PEFR), forced expiratory volume in 0.5 s/forced vital capacity (FEV0.5/FVC) and forced expiratory flow at 50% forced vital capacity (FEF50) showed the same general pattern of reduction as seen with R(L); however, these results were not statistically significant, most probably owing to individual monkey variability and the small number of monkeys (N = 6) used. A repeat challenge at 25 min after a primary challenge yielded increased R(L) in one monkey, suggesting that no absolute refractory period is present from CAIC. Results of these studies demonstrate that CAIC causes bronchoconstriction in monkeys and may be useful in further animal modeling studies designed to determine the asthmogenic/airway irritant potential of occupational toxicants. C1 CTR DIS CONTROL,NIOSH,EXPTL TOXICOL BRANCH,CINCINNATI,OH 45226. RP BIAGINI, RE (reprint author), CTR DIS CONTROL,NIOSH,DIV BIOMED & BEHAV SCI,APPL BIOL BRANCH,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 36 TC 3 Z9 3 U1 0 U2 0 PU JOHN WILEY & SONS LTD PI W SUSSEX PA BAFFINS LANE CHICHESTER, W SUSSEX, ENGLAND PO19 1UD SN 0260-437X J9 J APPL TOXICOL JI J. Appl. Toxicol. PD FEB PY 1991 VL 11 IS 1 BP 1 EP 6 DI 10.1002/jat.2550110102 PG 6 WC Toxicology SC Toxicology GA EW024 UT WOS:A1991EW02400001 PM 2022812 ER PT J AU NELSON, BK AF NELSON, BK TI EVIDENCE FOR BEHAVIORAL TERATOGENICITY IN HUMANS SO JOURNAL OF APPLIED TOXICOLOGY LA English DT Article DE BEHAVIORAL TERATOLOGY; TERATOLOGY; DEVELOPMENTAL TOXICOLOGY; DEVELOPMENTAL NEUROTOXICOLOGY; BEHAVIORAL DISORDERS; MENTAL RETARDATION; HYPERACTIVITY; REPRODUCTIVE TOXICOLOGY; CHILDREN; PREGNANCY ID FETAL ALCOHOL SYNDROME; HISTORICAL-PERSPECTIVE; TERATOLOGY; METHYLMERCURY; TOXICITY; EXPOSURE; GUIDELINES; UPDATE; FETUS; LEAD AB Central to both the scientific development of behavioral teratology and the attention paid to this field as an important area of study is establishing that prenatal exposure of pregnant females to exogenous agents leads to neurobehavioral disorders in their offspring. This tenet may not be questioned by the majority of toxicologists, but others may not be convinced. This paper serves as a brief review of the accumulated evidence that prenatal exposure to a number of drugs and environmental/industrial agents produces behavioral disorders in human infants. RP NELSON, BK (reprint author), NIOSH,DIV BIOMED & BEHAV SCI,C-24,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 72 TC 17 Z9 18 U1 0 U2 1 PU JOHN WILEY & SONS LTD PI W SUSSEX PA BAFFINS LANE CHICHESTER, W SUSSEX, ENGLAND PO19 1UD SN 0260-437X J9 J APPL TOXICOL JI J. Appl. Toxicol. PD FEB PY 1991 VL 11 IS 1 BP 33 EP 37 DI 10.1002/jat.2550110107 PG 5 WC Toxicology SC Toxicology GA EW024 UT WOS:A1991EW02400006 PM 2022814 ER PT J AU KIEHLBAUCH, JA BRENNER, DJ NICHOLSON, MA BAKER, CN PATTON, CM STEIGERWALT, AG WACHSMUTH, IK AF KIEHLBAUCH, JA BRENNER, DJ NICHOLSON, MA BAKER, CN PATTON, CM STEIGERWALT, AG WACHSMUTH, IK TI CAMPYLOBACTER-BUTZLERI SP-NOV ISOLATED FROM HUMANS AND ANIMALS WITH DIARRHEAL ILLNESS SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article ID CADMIUM CHLORIDE SUSCEPTIBILITY; AEROTOLERANT CAMPYLOBACTER; GENUS CAMPYLOBACTER; ORGANISMS; DIFFERENTIATION; UPSALIENSIS; HYDROLYSIS; FETUSES; AGAR AB Seventy-eight aerotolerant Campylobacter isolates were characterized phenotypically and by DNA hybridization (hydroxyapatite method at 50 and 65-degrees-C). Two DNA relatedness groups were found. (i) Sixty-four strains belonged to aerotolerant Campylobacter DNA hybridization group 2. These organisms were isolated from humans, primarily with diarrheal illness, and animals on several continents. Strains were aerotolerant at 30 and 36-degrees-C and catalase negative or weakly catalase positive, grew in media containing glycine and on MacConkey agar, were susceptible to nalidixic acid, and were resistant to cephalothin. The name Campylobacter butzleri sp. nov. is proposed for this group, (ii) DNA group 1 consisted of the type strain of Campylobacter cryaerophila and 13 additional strains isolated from 10 animals outside the United States and from three humans within the United States. This group was genetically diverse; five strains were closely related to the type strain of C. cryaerophila (DNA hybridization group 1A), and eight strains were more closely related to one another (DNA hybridization group 1B). Strains in DNA hybridization group 1B were phenotypically diverse, with two of eight strains resembling C. cryaerophila. The seven strains from DNA hybridization groups 1A and 1B which resembled C. cryaerophila andd the C. cryaerophila type strain were aerotolerant only at 30-degrees-C and catalase positive, did not grow in glycine or on MacConkey agar, were generally susceptible to naldixic acid, and were resistant to cephalothin. The remaining six strains of DNA hybridization group 1B phenotypically resembled C. butzleri; however, they were generally catalase positive and susceptible to nalidixic acid and cephalothin. DNA hybridization group 1B is not designated as a separate species at this time since it cannot, with certainty, be separated genetically from C. cryaerophila or phenotypically from C. butzleri. C1 CTR DIS CONTROL,CTR INFECT DIS,MENINGITIS & SPECIAL PATHOGENS LAB SECT,ATLANTA,GA 30333. CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,ATLANTA,GA 30333. CTR DIS CONTROL,CTR INFECT DIS,ANTIMICROB INVEST BRANCH,HOSP INFECT PROGRAM,ATLANTA,GA 30333. RP KIEHLBAUCH, JA (reprint author), CTR DIS CONTROL,CTR INFECT DIS,ENTER DIS LAB SECT,ATLANTA,GA 30333, USA. FU NCRR NIH HHS [RR-00165] NR 30 TC 138 Z9 140 U1 1 U2 5 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD FEB PY 1991 VL 29 IS 2 BP 376 EP 385 PG 10 WC Microbiology SC Microbiology GA ET578 UT WOS:A1991ET57800028 PM 2007646 ER PT J AU HATHEWAY, CL FARMER, JJ AF HATHEWAY, CL FARMER, JJ TI CLOSTRIDIUM-PERFRINGENS OR KLEBSIELLA-PNEUMONIAE AS THE CAUSE OF A FOOD-BORNE OUTBREAK SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Letter RP HATHEWAY, CL (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,ATLANTA,GA 30333, USA. NR 4 TC 2 Z9 2 U1 1 U2 1 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD FEB PY 1991 VL 29 IS 2 BP 415 EP 415 PG 1 WC Microbiology SC Microbiology GA ET578 UT WOS:A1991ET57800039 PM 2007653 ER PT J AU PADULA, SJ LINGENHELD, EG STABACH, PR CHOU, CHJ KONO, DH CLARK, RB AF PADULA, SJ LINGENHELD, EG STABACH, PR CHOU, CHJ KONO, DH CLARK, RB TI IDENTIFICATION OF ENCEPHALITOGENIC V-BETA-4-BEARING T-CELLS IN SJL MICE - FURTHER EVIDENCE FOR THE V-REGION DISEASE HYPOTHESIS SO JOURNAL OF IMMUNOLOGY LA English DT Article ID MYELIN BASIC-PROTEIN; AUTOIMMUNE ENCEPHALOMYELITIS; RECEPTORS; GENES; RAT; DETERMINANTS AB Experimental allergic encephalomyelitis (EAE) is an autoimmune disease of the central nervous system mediated by T cells bearing TCR of restricted heterogeneity. Thus, in the murine PL strain, V-beta-8.2 is used by 80% of the encephalitogenic T cells. This observation has led to the successful prevention and reversal of EAE by the in vivo use of mAb directed to these restricted gene products. In SJL mice, the V-beta-17a gene product has been shown to be used by approximately 50% of encephalitogenic T cells subsequent to immunization with a myelin basic protein (MBP)-derived peptide. However, the other V-beta genes used by encephalitogenic T cells in SJL EAE have remained uncharacterized. We now report, for the first time, the beta-chain-encoding DNA sequence of two encephalitogenic, MBP-reactive, SJL-derived T cell clones. These clones which are specific for H-2s and the carboxyl-terminus (amino acid 92-103) of MBP, use TCR encoded by V-beta-4. In addition, we demonstrate that the transfer of EAE by a heterogenous SJL-derived encephalitogenic T cell line can be prevented using an anti-V-beta-4 antibody in vivo. V-beta-4 usage has been previously described in a H-2u/MBP amino-terminus-reactive encephalitogenic T cell. The present findings may thus further support the "V region-disease" hypothesis. C1 AGCY TOX SUBST & DIS REGISTRY, DIV TOXICOL, ATLANTA, GA 30333 USA. Scripps Res Inst, RES INST, DEPT IMMUNOL, LA JOLLA, CA 92037 USA. RP PADULA, SJ (reprint author), UNIV CONNECTICUT, SCH MED, DEPT MED, DIV RHEUMAT DIS, 263 FARMINGTON AVE, FARMINGTON, CT 06030 USA. FU NIADDK NIH HHS [AM-20621]; NIAMS NIH HHS [AR/AI 39361] NR 24 TC 61 Z9 61 U1 0 U2 0 PU AMER ASSOC IMMUNOLOGISTS PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 0022-1767 J9 J IMMUNOL JI J. Immunol. PD FEB 1 PY 1991 VL 146 IS 3 BP 879 EP 883 PG 5 WC Immunology SC Immunology GA EU926 UT WOS:A1991EU92600014 PM 1703184 ER PT J AU KHABBAZ, RF HARTEL, D LAIRMORE, M HORSBURGH, CR SCHOENBAUM, EE ROBERTS, B HARTLEY, TM FRIEDLAND, G AF KHABBAZ, RF HARTEL, D LAIRMORE, M HORSBURGH, CR SCHOENBAUM, EE ROBERTS, B HARTLEY, TM FRIEDLAND, G TI HUMAN LYMPHOTROPIC-T VIRUS TYPE-II (HTLV-II) INFECTION IN A COHORT OF NEW-YORK INTRAVENOUS-DRUG-USERS - AN OLD INFECTION SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID POLYMERASE; ABUSERS; AIDS; RISK; HIV AB To identify risk factors for human T lymphotropic virus type II (HTLV-II) infection in intravenous drug users (IVDUs), participants in a longitudinal study of human immunodeficiency virus (HIV) infection in a New York methadone maintenance program were studied. Of 270 participants tested for HTLV-I/II, 21 (8%) were seropositive. Of those, 15 (71%) had HTLV-II-specific sequences by polymerase chain reaction (PCR) and 1 (5%) had both HTLV-1- and -II-specific sequences; 3 persons with indeterminate serologic results were also PCR-positive for HTLV-II. HTLV-II infection was significantly associated with older age but was not predicted by sex, race, socioeconomic status, transfusion history, or HIV infection status. Behavioral factors since 1978, such as duration and frequency of intravenous drug use, needle sharing, visits to shooting galleries, or number of sex partners, were also not associated with HTLV-II infection. These findings are in contrast with the association of these risk factors with HIV in this group and suggest that, among IVDUs, HTLV-II is an older endemic infection that is less efficiently transmitted than HIV. C1 CTR DIS CONTROL,DIV HIV AIDS,ATLANTA,GA 30333. MONTEFIORE HOSP & MED CTR,ALBERT EINSTEIN COLL MED HOSP,DEPT EPIDEMIOL & SOCIAL MED,BRONX,NY 10461. MONTEFIORE HOSP & MED CTR,ALBERT EINSTEIN COLL MED HOSP,DEPT MED,BRONX,NY 10461. RP KHABBAZ, RF (reprint author), CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,RETROVIRUS DIS BRANCH,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 24 TC 48 Z9 48 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD FEB PY 1991 VL 163 IS 2 BP 252 EP 256 PG 5 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EU573 UT WOS:A1991EU57300006 PM 1988509 ER PT J AU CARTTER, ML FARLEY, TA ROSENGREN, S QUINN, DL GILLESPIE, SM GARY, GW HADLER, JL AF CARTTER, ML FARLEY, TA ROSENGREN, S QUINN, DL GILLESPIE, SM GARY, GW HADLER, JL TI OCCUPATIONAL RISK-FACTORS FOR INFECTION WITH PARVOVIRUS B19 AMONG PREGNANT-WOMEN SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID HYDROPS FETALIS; OUTBREAK; DISEASE AB To identify exposures associated with parvovirus B19 infection during pregnancy, two groups of pregnant women were studied during an outbreak of erythema infectiosum (EI). Of 796 pregnant women from Connecticut who were tested serologically because of perceived exposure to B19, 53% (419/796) had serologic evidence of previous B19 infection, and 6% (23/376) of the rest had evidence of recent infection. Of 121 pregnant women who had not requested testing but who lived in a community where a large outbreak of EI had occurred among schoolchildren, 36% (43/121) had serologic evidence of previous infection, and only 3% (2/78) of the rest had had a recent infection. In the exposed group, 479 women returned a supplemental exposure questionnaire. The highest infection rates among susceptible women were for schoolteachers (16%, 10/64), followed by day care workers (9%, 2/22) and homemakers (9%, 4/46). Women working outside the home but not in school or day care settings had the lowest risk (4%, 3/80). This study suggests that there is risk for B19 infection in selected occupational settings and in households. C1 UNIV CONNECTICUT,CTR HLTH,DEPT PEDIAT,DIV MED GENET,FARMINGTON,CT 06032. CTR DIS CONTROL,DIV FIELD SERV & VIRAL DIS,ATLANTA,GA 30333. RP CARTTER, ML (reprint author), CONNECTICUT DEPT HLTH SERV,EPIDEMIOL PROGRAM,150 WASHINGTON ST,HARTFORD,CT 06106, USA. NR 22 TC 39 Z9 40 U1 0 U2 1 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD FEB PY 1991 VL 163 IS 2 BP 282 EP 285 PG 4 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EU573 UT WOS:A1991EU57300011 PM 1846391 ER PT J AU ROBERTSON, BH KHANNA, B NAINAN, OV MARGOLIS, HS AF ROBERTSON, BH KHANNA, B NAINAN, OV MARGOLIS, HS TI EPIDEMIOLOGIC PATTERNS OF WILD-TYPE HEPATITIS-A VIRUS DETERMINED BY GENETIC-VARIATION SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID COMPLETE NUCLEOTIDE-SEQUENCE; ENZYMATIC AMPLIFICATION; ATTENUATED HEPATITIS; MOLECULAR-CLONING; DNA-POLYMERASE; STRAINS; CDNA; CLASSIFICATION; NEUTRALIZATION; PROTEINS AB Hepatitis A virus (HAV) isolates from different parts of the world are a single serotype. However, genetic analysis of the VP1 genome region of published HAV sequences suggested that distinct genotypes of HAV could be defined based upon the geographic source of the original isolates. To circumvent the process of cell culture adaptation or animal passage, a 247-bp segment within the VP1 genome region of wild-type HAV was amplified by reverse transcription followed by polymerase chain reaction amplification in the presence of negative- and positive-sense primers. From the sequences obtained from 22 epidemiologically distinct HAV isolates, three genetic groups of HAV could be delineated. Two of the groups differed by 10%, while the third group differed from other isolates by approximately 20%. These investigations indicate that HAV isolates from different parts of the world can be differentiated genetically, which will facilitate studies of epidemiologic transmission. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,ATLANTA,GA 30333. RP ROBERTSON, BH (reprint author), CTR DIS CONTROL,WHO COLLABORATING CTR REFERENCE & RES VIRAL HEPATITIS,ATLANTA,GA 30333, USA. NR 35 TC 115 Z9 117 U1 0 U2 1 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD FEB PY 1991 VL 163 IS 2 BP 286 EP 292 PG 7 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EU573 UT WOS:A1991EU57300012 PM 1846392 ER PT J AU JOHANSSON, ME BROWN, M HIERHOLZER, JC THORNER, A USHIJIMA, H WADELL, G AF JOHANSSON, ME BROWN, M HIERHOLZER, JC THORNER, A USHIJIMA, H WADELL, G TI GENOME ANALYSIS OF ADENOVIRUS TYPE-31 STRAINS FROM IMMUNOCOMPROMISED AND IMMUNOCOMPETENT PATIENTS SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID BONE-MARROW TRANSPLANTATION; RESTRICTION ENZYME ANALYSIS; ENTERIC ADENOVIRUS-40; IMMUNE-DEFICIENCY; INFECTION; RECIPIENT; GASTROENTERITIS; EPIDEMIOLOGY; ANTIBODIES; PNEUMONIA AB Adenovirus type 31 (Ad31) was isolated from 15 immunocompromised patients in 12 of whom seroconversion was also recorded. Ad31 infection has a substantial clinical relevance since 8 of 10 with lower respiratory tract infection and 4 of 4 with hepatitis died. Therefore, Ad31 isolates from immunocompetent and immunodeficient hosts were compared by restriction endonuclease analysis. Nine genome types were identified among the 79 Ad31 isolates. Pairwise comparison of comigrating restriction fragments indicated that the genome types could be divided into three genomic clusters. Several Ad31 genome types were isolated from immunocompromised patients, but no highly virulent genome type could be found. A genome type was identified in a child with severe combined immunodeficiency who originally was infected with another genome type. This observation is suggested to have evolutionary implications. C1 UMEA UNIV,DEPT VIROL,S-90187 UMEA,SWEDEN. UNIV TORONTO,DEPT MICROBIOL,TORONTO M5S 1A1,ONTARIO,CANADA. CTR DIS CONTROL,DIV VIRAL DIS,RESP & ENTER VIRUS BRANCH,ATLANTA,GA 30333. NATL INST HLTH,DEPT ENTEROVIRUSES,DIV SPECIAL PATHOGENS,TOKYO 141,JAPAN. NATL INST HLTH,DIV AIDS VIRUS,TOKYO 141,JAPAN. RP JOHANSSON, ME (reprint author), KAROLINSKA HOSP,DEPT CLIN MICROBIOL,VIROL SECT,S-10401 STOCKHOLM 60,SWEDEN. NR 42 TC 19 Z9 19 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD FEB PY 1991 VL 163 IS 2 BP 293 EP 299 PG 7 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EU573 UT WOS:A1991EU57300013 PM 1988511 ER PT J AU STROCKBINE, NA PARSONNET, J GREENE, K KIEHLBAUCH, JA WACHSMUTH, IK AF STROCKBINE, NA PARSONNET, J GREENE, K KIEHLBAUCH, JA WACHSMUTH, IK TI MOLECULAR EPIDEMIOLOGIC TECHNIQUES IN ANALYSIS OF EPIDEMIC AND ENDEMIC SHIGELLA-DYSENTERIAE TYPE-1 STRAINS SO JOURNAL OF INFECTIOUS DISEASES LA English DT Note ID DNA AB During 1988 the number of Shigella dysenteriae type 1 infections reported in the United States increased fivefold. To determine if recent isolates from Mexico were related to those that caused epidemics of dysentery worldwide, Southern hybridization analysis was done with Shiga toxin and ribosomal RNA gene probes. Western hemisphere and Eastern Hemisphere strains differed by the size of a single EcoRI fragment carrying the Shiga toxin genes. Three ribosomal DNA (rDNA) patterns were observed, which correlated with the strain's continental origin for 81 of 83 isolates tested. Together the Shiga toxin and rDNA probe results indicated that recent Mexican isolates were chromosomally similar to earlier Central American isolates and distinct from Asian and African strains. This suggests there has been no significant exchange of organisms between continents in recent decades and that the 1988 outbreak in Mexico was caused by strains present in Central America since at least 1962. RP STROCKBINE, NA (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,ENTER DIS BRANCH,ENTER DIS LAB SECT,ATLANTA,GA 30333, USA. NR 9 TC 19 Z9 19 U1 0 U2 1 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD FEB PY 1991 VL 163 IS 2 BP 406 EP 409 PG 4 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EU573 UT WOS:A1991EU57300033 PM 1671055 ER PT J AU HEIMBERGER, T BIRKHEAD, G BORNSTEIN, D SAME, K MORSE, D AF HEIMBERGER, T BIRKHEAD, G BORNSTEIN, D SAME, K MORSE, D TI CONTROL OF NOSOCOMIAL LEGIONNAIRES-DISEASE THROUGH HOT WATER FLUSHING AND SUPPLEMENTAL CHLORINATION OF POTABLE WATER SO JOURNAL OF INFECTIOUS DISEASES LA English DT Letter C1 CTR DIS CONTROL,DIV FIELD SERV,EPIDEMIOL PROGRAM OFF,ATLANTA,GA 30333. SUNY SYRACUSE,HLTH SCI CTR,SYRACUSE,NY. RP HEIMBERGER, T (reprint author), NEW YORK STATE DEPT HLTH,EMPIRE STATE PLAZA,TOWER BLDG,RM 651,ALBANY,NY 12237, USA. NR 1 TC 13 Z9 13 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD FEB PY 1991 VL 163 IS 2 BP 413 EP 413 PG 1 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EU573 UT WOS:A1991EU57300035 PM 1988527 ER PT J AU ROBINSON, CF LALICH, NR BURNETT, CA SESTITO, JP FRAZIER, TM FINE, LJ AF ROBINSON, CF LALICH, NR BURNETT, CA SESTITO, JP FRAZIER, TM FINE, LJ TI ELECTROMAGNETIC-FIELD EXPOSURE AND LEUKEMIA MORTALITY IN THE UNITED-STATES SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE LA English DT Note ID ELECTRICAL WORKERS; MAGNETIC-FIELDS C1 NIOSH,DIV SURVEILLANCE,HAZARD EVALUAT & FIELD STUDIES,CINCINNATI,OH 45226. RP ROBINSON, CF (reprint author), NIOSH,SURVEILLANCE BRANCH,ILLNESS EFFECTS SECT,MAIL STOP R-18,CINCINNATI,OH 45226, USA. NR 13 TC 12 Z9 12 U1 0 U2 1 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 1076-2752 J9 J OCCUP ENVIRON MED JI J. Occup. Environ. Med. PD FEB PY 1991 VL 33 IS 2 BP 160 EP 162 PG 3 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EX533 UT WOS:A1991EX53300014 PM 2016656 ER PT J AU PARKE, JC SCHNEERSON, R REIMER, C BLACK, C WELFARE, S BRYLA, D LEVI, L PAVLIAKOVA, D CRAMTON, T SCHULZ, D CADOZ, M ROBBINS, JB AF PARKE, JC SCHNEERSON, R REIMER, C BLACK, C WELFARE, S BRYLA, D LEVI, L PAVLIAKOVA, D CRAMTON, T SCHULZ, D CADOZ, M ROBBINS, JB TI CLINICAL AND IMMUNOLOGICAL RESPONSES TO HAEMOPHILUS-INFLUENZAE TYPE-B-TETANUS TOXOID CONJUGATE VACCINE IN INFANTS INJECTED AT 3, 5, 7, AND 18 MONTHS OF AGE SO JOURNAL OF PEDIATRICS LA English DT Article ID CAPSULAR POLYSACCHARIDE; SERUM ANTIBODIES; IMMUNIZATION AB The safety and immunogenicity of Haemophilus influenzae type b-tetanus toxoid conjugate vaccine (Hib-TT) were evaluated in 77 healthy infants receiving injections at 3, 5, 7, and 18 months of age. No serious local or systemic reactions were noted. After the first injection the geometric mean Hib antibody level rose to 0.55-mu-g/ml, and each subsequent injection elicited a statistically significant rise in the geometric mean. The percentage of vaccinees with Hib antibody levels > 0.15-mu-g/ml serum was 75.5% after the first, 97.4% after the second, and 100% after the third Hib-TT injection. This percentage fell to 90.9% at 18 months of age but rose again to 100% after the fourth injection. Control infants (n = 10) injected with diphtheria-tetanus toxoid-pertussis vaccine only had nondetectable levels after the second injection. Hib-TT elicited increases of Hib antibody in all isotypes: IgG > IgM > IgA. Among IgG subclasses the highest increases were of IgG1. All vaccinated subjects had > 0.01 U/ml of TT antibody (estimated protective level) throughout the study. We conclude that Hib-TT, injected at 3, 5, 7, and 18 months, is safe and induces protective levels of antibodies during the age of highest incidence of meningitis caused by Hib. C1 NICHHD, BETHESDA, MD 20892 USA. CTR DIS CONTROL, ATLANTA, GA 30333 USA. PASTEUR MERIEUX SERUMS & VACCINES, LYONS, FRANCE. NR 18 TC 50 Z9 51 U1 1 U2 1 PU MOSBY-ELSEVIER PI NEW YORK PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA SN 0022-3476 EI 1097-6833 J9 J PEDIATR-US JI J. Pediatr. PD FEB PY 1991 VL 118 IS 2 BP 184 EP 190 DI 10.1016/S0022-3476(05)80480-9 PG 7 WC Pediatrics SC Pediatrics GA EX302 UT WOS:A1991EX30200003 PM 1993943 ER PT J AU MONROE, SS STINE, SE GORELKIN, L HERRMANN, JE BLACKLOW, NR GLASS, RI AF MONROE, SS STINE, SE GORELKIN, L HERRMANN, JE BLACKLOW, NR GLASS, RI TI TEMPORAL SYNTHESIS OF PROTEINS AND RNAS DURING HUMAN ASTROVIRUS INFECTION OF CULTURED-CELLS SO JOURNAL OF VIROLOGY LA English DT Article ID SERIAL PROPAGATION; GASTROENTERITIS; CALICIVIRUS; VIRUS; ROTAVIRUS; SEROTYPES; OUTBREAK; ASSAYS; FECES AB Astroviruses are nonenveloped particles with a distinctive star-shaped surface structure that have been detected by electron microscopy in stool samples from humans and animals with gastroenteritis. We examined the patterns of macromolecular synthesis in astrovirus-infected cells with a goal of establishing a molecular basis for taxonomic classification. Trypsin is required for continuous replication of astrovirus in cultured cells; however, during a single cycle of infection, astrovirus antigen was synthesized earlier and at higher levels when serum, rather than trypsin, was included in the growth medium. This enhanced production of antigen, as measured by enzyme immunoassay, was accompanied by the appearance of aggregates of virus particles in the cytoplasm of infected cells. During astrovirus replication in cells cultured in the presence of serum, we detected a single infection-specific protein (90 kDa) beginning at 12 h postinfection. This protein was recognized by antiastrovirus rabbit serum and was sensitive to trypsin digestion in vitro, with the concomitant appearance of three smaller immunoreactive proteins (31, 29, and 20 kDa). We also detected two dactinomycin-resistant RNAs (7.2 and 2.8 kb), both of which were polyadenylated, in the cytoplasm of astrovirus-infected cells. The larger of these two RNAs is presumably the viral genome, whereas the smaller species may be a subgenomic messenger. Comparison of the proteins and RNAs synthesized in astrovirus-infected cells with those of the recognized families of nonenveloped single-stranded RNA animal viruses suggests that astroviruses should not be classified as members of either Caliciviridae or Picornaviridae. C1 CTR DIS CONTROL,DIV IMMUNOL ONCOL & HEMATOL DIS,EXPTL PATHOL BRANCH,ATLANTA,GA 30333. UNIV MASSACHUSETTS,SCH MED,DIV INFECT DIS,WORCESTER,MA 01605. RP MONROE, SS (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,RESP & ENTEROVIRUS BRANCH,ATLANTA,GA 30333, USA. OI Monroe, Stephan/0000-0002-5424-716X NR 39 TC 74 Z9 75 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0022-538X J9 J VIROL JI J. Virol. PD FEB PY 1991 VL 65 IS 2 BP 641 EP 648 PG 8 WC Virology SC Virology GA ET445 UT WOS:A1991ET44500011 PM 1987373 ER PT J AU HEATH, GW FORD, ES CRAVEN, TE MACERA, CA JACKSON, KL PATE, RR AF HEATH, GW FORD, ES CRAVEN, TE MACERA, CA JACKSON, KL PATE, RR TI EXERCISE AND THE INCIDENCE OF UPPER RESPIRATORY-TRACT INFECTIONS SO MEDICINE AND SCIENCE IN SPORTS AND EXERCISE LA English DT Article DE RUNNING; EXERTION; ILLNESS; COLDS; SPORTS ID PHYSICAL-ACTIVITY; MORTALITY; FITNESS; DISEASE AB We examined illness patterns in a cohort of 530 male and female runners who completed a monthly log for 12 months. The average number of upper respiratory tract infections (URTIs) per person per year for the cohort was 1.2. An upper respiratory tract infection was indicated by the report of any of the following symptoms; runny nose, sore throat, or cough. Using a multiple logistic regression model, the following factors were found to be associated with having one or more URTIs in the follow-up period: living alone (odds ratio = 2.27, 95% CI = 1.01, 5.09), running mileage (486-865 miles, odds ratio = 2.00, 95% CI = 1.01, 2.78; 866-1388 miles, odds ratio = 3.50, 95% CI = 1.52, 4.44; > 1388 miles, odds ratio = 2.96, 95% CI = 1.30, 3.68), body mass index greater than the 75th percentile (odds ratio = 0.58, 95% CI = 0.35, 0.94), and male gender (odds ratio = 0.14, 95% CI = 0.03, 0.68). A significant interaction was found to exist between gender and alcohol use, with the association between alcohol use and upper respiratory tract infections being positive in males and negative in females. These results suggest that running dosage (mileage) is a significant risk factor for upper respiratory tract infections in this group of exercisers. C1 UNIV S CAROLINA,SCH PUBL HLTH,DEPT EXERCISE SCI,COLUMBIA,SC 29208. UNIV S CAROLINA,SCH PUBL HLTH,DEPT EPIDEMIOL & BIOSTAT,COLUMBIA,SC 29208. RP HEATH, GW (reprint author), CTR DIS CONTROL,CARDIOVASC HLTH BRANCH,ATLANTA,GA 30333, USA. NR 28 TC 146 Z9 148 U1 2 U2 10 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0195-9131 J9 MED SCI SPORT EXER JI Med. Sci. Sports Exerc. PD FEB PY 1991 VL 23 IS 2 BP 152 EP 157 PG 6 WC Sport Sciences SC Sport Sciences GA EX435 UT WOS:A1991EX43500002 PM 2017010 ER PT J AU KAPLAN, JE LITCHFIELD, B ROUAULT, C LAIRMORE, MD LUO, CC WILLIAMS, L BREW, BJ PRICE, RW JANSSEN, R STONEBURNER, R OU, CY FOLKS, T DE, B AF KAPLAN, JE LITCHFIELD, B ROUAULT, C LAIRMORE, MD LUO, CC WILLIAMS, L BREW, BJ PRICE, RW JANSSEN, R STONEBURNER, R OU, CY FOLKS, T DE, B TI HTLV-I ASSOCIATED MYELOPATHY ASSOCIATED WITH BLOOD-TRANSFUSION IN THE UNITED-STATES - EPIDEMIOLOGIC AND MOLECULAR EVIDENCE LINKING DONOR AND RECIPIENT SO NEUROLOGY LA English DT Article ID CELL LEUKEMIA-LYMPHOMA; VIRUS TYPE-I; COMPLETE NUCLEOTIDE-SEQUENCE; DNA C1 CTR DIS CONTROL,DIV HIV AIDS,LAB INVEST BRANCH,ATLANTA,GA 30333. CTR DIS CONTROL,CTR INFECT DIS,ATLANTA,GA 30333. BROWARD CTY HLTH DEPT,FT LAUDERDALE,FL. BROWARD COMMUNITY BLOOD CTR,LAUDERHILL,FL. MEM SLOAN KETTERING CANC CTR,NEW YORK,NY 10021. NEW YORK CITY DEPT HLTH,NEW YORK,NY 10013. RP KAPLAN, JE (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,RETROVIRUS DIS BRANCH,ATLANTA,GA 30333, USA. RI Brew, Bruce/J-6513-2012 NR 29 TC 39 Z9 40 U1 0 U2 1 PU LITTLE BROWN CO PI BOSTON PA 34 BEACON STREET, BOSTON, MA 02108-1493 SN 0028-3878 J9 NEUROLOGY JI Neurology PD FEB PY 1991 VL 41 IS 2 BP 192 EP 197 PN 1 PG 6 WC Clinical Neurology SC Neurosciences & Neurology GA EX218 UT WOS:A1991EX21800006 PM 1992361 ER PT J AU LEVIN, HS EISENBERG, HM GARY, HE MARMAROU, A FOULKES, MA JANE, JA MARSHALL, LF PORTMAN, SM AF LEVIN, HS EISENBERG, HM GARY, HE MARMAROU, A FOULKES, MA JANE, JA MARSHALL, LF PORTMAN, SM TI INTRACRANIAL HYPERTENSION IN RELATION TO MEMORY FUNCTIONING DURING THE 1ST YEAR AFTER SEVERE HEAD-INJURY SO NEUROSURGERY LA English DT Article DE HEAD INJURY; INTRACRANIAL PRESSURE; MEMORY ID INTRA-CRANICAL PRESSURE; COMA AB The relationship between intracranial hypertension and residual memory deficit after closed head injury was evaluated using the 6-month and 1-year neurobehavioral outcome data obtained by the Traumatic Coma Data Bank. Intracranial pressure was analyzed using the percentage of time that it exceeded 20 mm Hg and the maximum value recorded during the first 72 hours after injury. Memory measures included recall of word lists, prose recall, and visual memory for designs that were obtained 6 months (n = 149) and 1 year (n = 132) after injury. Intracranial hypertension occurred in more than half of the Traumatic Coma Data Bank cohort who met the criteria for the neurobehavioral follow-up study. Linear regression analysis disclosed an effect of elevated intracranial pressure on some, but not all, measures of memory at 6 months, whereas the results were negative for the 1-year follow-up examination. We conclude that the elevation of intracranial pressure exerts little if any effect on later memory functioning, and that any effect it does have diminishes over 1 year in survivors of severe head injury. C1 UNIV TEXAS,MED BRANCH,DEPT NEUROL,GALVESTON,TX 77550. CTR DIS CONTROL,ATLANTA,GA 30333. VIRGINIA COMMONWEALTH UNIV,MED COLL VIRGINIA,DEPT NEUROSURG,RICHMOND,VA 23298. UNIV CALIF SAN DIEGO,DIV NEUROSURG,LA JOLLA,CA 92093. NIH,OFF BIOMETRY,BETHESDA,MD 20892. UNIV VIRGINIA,DEPT NEUROSURG,CHARLOTTESVILLE,VA 22903. RP LEVIN, HS (reprint author), UNIV TEXAS,MED BRANCH,DIV NEUROSURG D-73,GALVESTON,TX 77550, USA. FU NINDS NIH HHS [N01-NS-3-2339, N01-NS-3-2340, N01-NS-3-2341] NR 12 TC 36 Z9 37 U1 2 U2 2 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0148-396X J9 NEUROSURGERY JI Neurosurgery PD FEB PY 1991 VL 28 IS 2 BP 196 EP 200 PG 5 WC Clinical Neurology; Surgery SC Neurosciences & Neurology; Surgery GA EU430 UT WOS:A1991EU43000004 PM 1997886 ER PT J AU SCHANTZ, PM GOTTSTEIN, B AMMANN, R LANIER, A AF SCHANTZ, PM GOTTSTEIN, B AMMANN, R LANIER, A TI HYDATID AND THE ARCTIC SO PARASITOLOGY TODAY LA English DT Editorial Material C1 UNIV ZURICH,INST PARASITOL,CH-8057 ZURICH,SWITZERLAND. UNIV HOSP ZURICH,DEPT INTERNAL MED,CH-8091 ZURICH,SWITZERLAND. CTR DIS CONTROL,ANCHORAGE,AK 99510. RP SCHANTZ, PM (reprint author), CTR DIS CONTROL,DIV PARASIT DIS,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 0 TC 23 Z9 23 U1 0 U2 1 PU ELSEVIER SCI LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB SN 0169-4758 J9 PARASITOL TODAY JI Parasitol. Today PD FEB PY 1991 VL 7 IS 2 BP 35 EP 36 DI 10.1016/0169-4758(91)90185-Q PG 2 WC Parasitology SC Parasitology GA EW886 UT WOS:A1991EW88600003 ER PT J AU CALDWELL, MB ROGERS, MF AF CALDWELL, MB ROGERS, MF TI EPIDEMIOLOGY OF PEDIATRIC HIV-INFECTION SO PEDIATRIC CLINICS OF NORTH AMERICA LA English DT Article ID HUMAN IMMUNODEFICIENCY VIRUS; NATURAL-HISTORY; UNITED-STATES; INFANTS BORN; TYPE-1; CHILDREN; TRANSMISSION; BLOOD; TRANSFUSION; ANTIBODY RP CALDWELL, MB (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,PEDIAT & FAMILY STUDIES SECT,MAILSTOP G-29,ATLANTA,GA 30333, USA. NR 43 TC 28 Z9 28 U1 0 U2 0 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0031-3955 J9 PEDIATR CLIN N AM JI Pediatr. Clin. N. Am. PD FEB PY 1991 VL 38 IS 1 BP 1 EP 16 PG 16 WC Pediatrics SC Pediatrics GA EU526 UT WOS:A1991EU52600002 PM 1987511 ER PT J AU ROILIDES, E BLACK, C REIMER, C RUBIN, M VENZON, D PIZZO, PA AF ROILIDES, E BLACK, C REIMER, C RUBIN, M VENZON, D PIZZO, PA TI SERUM IMMUNOGLOBULIN-G SUBCLASSES IN CHILDREN INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 SO PEDIATRIC INFECTIOUS DISEASE JOURNAL LA English DT Article DE IGG SUBCLASSES; HUMAN IMMUNODEFICIENCY VIRUS-1 INFECTION; CHILDREN ID ANTIBODY-RESPONSE; ACQUIRED IMMUNODEFICIENCY; LYMPHADENOPATHY SYNDROME; RECURRENT INFECTIONS; DEFICIENCY; AIDS; RATIOS; ASSAYS AB We studied serum concentrations of IgG subclasses in 47 human immunodeficiency virus 1-infected (17 asymptomatic and 30 symptomatic) children. Thirty-nine of 47 (83%) had an abnormality of at least 1 subclass. Sixteen had only elevated IgG1, 6 had only elevated IgG3 and 12 had elevated IgG1 and IgG3 concentrations. IgG2, IgG4 and combined IgG2-IgG4 deficiency was found in 3, 4 and 4 patients, respectively. IgG2 concentrations did not differ between patients with (n = 23) or without (n = 24) bacterial infections. Additionally the number of bacterial infections was similar between the patients with normal or low IgG2 and/or low IgG4. These data indicate that IgG subclass abnormalities are found in most children with human immunodeficiency virus 1 infection, but quantitative deficiencies of specific subclasses do not appear to explain the high frequency of bacterial infections occurring in these patients. C1 NCI,PEDIAT BRANCH,NCI BLDG,RM 13N240,BETHESDA,MD 20892. NCI,PEDIAT ONCOL BRANCH,INFECT DIS SECT,BETHESDA,MD 20892. NCI,BIOSTAT & DATA MANAGEMENT SECT,BETHESDA,MD 20892. CTR DIS CONTROL,CTR INFECT DIS,DIV IMMUNOL ONCOL & HEMATOL DIS,ATLANTA,GA 30333. RI Venzon, David/B-3078-2008 NR 33 TC 20 Z9 20 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0891-3668 J9 PEDIATR INFECT DIS J JI Pediatr. Infect. Dis. J. PD FEB PY 1991 VL 10 IS 2 BP 134 EP 139 DI 10.1097/00006454-199102000-00012 PG 6 WC Immunology; Infectious Diseases; Pediatrics SC Immunology; Infectious Diseases; Pediatrics GA EX489 UT WOS:A1991EX48900012 PM 2062605 ER PT J AU BUTLER, JC AGGER, WA KURZYNSKI, TA DAVIS, JP AF BUTLER, JC AGGER, WA KURZYNSKI, TA DAVIS, JP TI PLEUROPNEUMONIA CAUSED BY MULTIPLY RESISTANT HAEMOPHILUS-INFLUENZAE TYPE-B INFECTION ACQUIRED IN THE UNITED-STATES SO PEDIATRIC INFECTIOUS DISEASE JOURNAL LA English DT Note DE HAEMOPHILUS-INFLUENZAE TYPE-B; PNEUMONIA; EMPYEMA; AMPICILLIN AND CHLORAMPHENICOL RESISTANCE; HMONG; REFUGEE ID PLASMID-MEDIATED RESISTANCE; HEMOPHILUS-INFLUENZAE; BACTERIAL-MENINGITIS; AMPICILLIN; CHLORAMPHENICOL; THERAPY; SUSCEPTIBILITY; CHILDREN; INFANTS C1 CTR DIS CONTROL, EPIDEMIOL PROGRAM OFF, DIV FIELD SERV, ATLANTA, GA 30333 USA. GUNDERSON MED FDN, LA CROSSE, WI USA. WISCONSIN STATE LAB HYG, MADISON, WI USA. UNIV WISCONSIN, DEPT PEDIAT, MADISON, WI 53706 USA. UNIV WISCONSIN, DEPT PREVENT MED, MADISON, WI 53706 USA. RP BUTLER, JC (reprint author), WISCONSIN DEPT HLTH & SOCIAL SERV, BUR COMMUNITY HLTH & PREVENT, MADISON, WI 53701 USA. NR 17 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT WILLIAMS & WILKINS PI PHILADELPHIA PA 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA SN 0891-3668 EI 1532-0987 J9 PEDIATR INFECT DIS J JI Pediatr. Infect. Dis. J. PD FEB PY 1991 VL 10 IS 2 BP 160 EP 163 PG 4 WC Immunology; Infectious Diseases; Pediatrics SC Immunology; Infectious Diseases; Pediatrics GA EX489 UT WOS:A1991EX48900019 PM 2062611 ER PT J AU ARAL, SO HOLMES, KK AF ARAL, SO HOLMES, KK TI SEXUALLY-TRANSMITTED DISEASES IN THE AIDS ERA SO SCIENTIFIC AMERICAN LA English DT Article AB The three classic sexually transmitted diseases-gonorrhea, syphilis and chancroid-have nearly disappeared in almost every industrialized nation. The exception is the U.S., where drug-resistant strains of these diseases are ravaging urban minority populations. The causes of this tragic epidemic are poverty, social disintegration, prostitution and drug addiction. C1 UNIV WASHINGTON,CTR AIDS & SEXUALLY TRANSMITTED DIS,SEATTLE,WA 98195. RP ARAL, SO (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,DIV SEXUALLY TRANSMITTED DIS & HIV PREVENT,BEHAV STUDIES SECT,ATLANTA,GA 30333, USA. NR 4 TC 81 Z9 81 U1 0 U2 1 PU SCI AMERICAN INC PI NEW YORK PA 415 MADISON AVE, NEW YORK, NY 10017 SN 0036-8733 J9 SCI AM JI Sci.Am. PD FEB PY 1991 VL 264 IS 2 BP 62 EP 69 PG 8 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA EU604 UT WOS:A1991EU60400008 PM 1848025 ER PT J AU HILLS, B BURT, S MOSS, CE AF HILLS, B BURT, S MOSS, CE TI TAKE PRECAUTIONS WHEN CUTTING PVC-COATED STEEL SO WELDING JOURNAL LA English DT Note RP HILLS, B (reprint author), NIOSH,CTR PHYSIOL,CINCINNATI,OH 45226, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER WELDING SOC PI MIAMI PA PO BOX 351040, MIAMI, FL 33135 SN 0043-2296 J9 WELD J JI Weld. J. PD FEB PY 1991 VL 70 IS 2 BP 55 EP 56 PG 2 WC Metallurgy & Metallurgical Engineering SC Metallurgy & Metallurgical Engineering GA EV943 UT WOS:A1991EV94300006 ER PT J AU SMITH, JS FISHBEIN, DB RUPPRECHT, CE CLARK, K AF SMITH, JS FISHBEIN, DB RUPPRECHT, CE CLARK, K TI UNEXPLAINED RABIES IN 3 IMMIGRANTS IN THE UNITED-STATES - A VIROLOGICAL INVESTIGATION SO NEW ENGLAND JOURNAL OF MEDICINE LA English DT Article ID MONOCLONAL-ANTIBODIES; ANTIGENIC SITES; VIRUS; NUCLEOPROTEIN; DIAGNOSIS AB Background. Extensive investigation of three patients who died of rabies in the United States failed to reveal any source of exposure to the disease. The three patients had immigrated to the United States from areas in Laos, the Philippines, and Mexico where rabies is endemic. Methods. We studied rabies viruses isolated from the three patients, other patients with a known source of exposure, and animals in the United States, Thailand (as a proxy for Laos), the Philippines, and Mexico. The viruses were characterized by indirect immunofluorescence and neutralization tests according to their reactions to panels of monoclonal antibodies. Transcribed complementary DNA from these isolates was amplified by the polymerase chain reaction; the DNA product was then analyzed by differential digestion with restriction enzymes. Results. The viral isolate from each of the three patients was a rabies variant with distinctive antigenic or genetic characteristics. For each of the three isolates, identical variants were found in specimens from rabid animals obtained from or near the country in which the patient lived before immigrating to the United States. None of these variants were found among the isolates collected from rabid animals in the United States Conclusions. Rabies infection in these three patients did not originate in the United States but resulted from exposures in Laos, the Philippines, and Mexico. Since the three patients had lived in the United States for 4 years, 6 years, and 11 months, our findings suggest that the onset of the clinical manifestations of rabies occurred after long incubation periods. C1 WISTAR INST,RABIES UNIT,PHILADELPHIA,PA 19104. TEXAS STATE HLTH DEPT,DIV ZOONOSES CONTROL,AUSTIN,TX. RP SMITH, JS (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,VIRAL & RICKETTSIAL ZOONOSES BRANCH,ATLANTA,GA 30333, USA. NR 49 TC 145 Z9 157 U1 2 U2 2 PU MASS MEDICAL SOC PI BOSTON PA 10 SHATTUCK, BOSTON, MA 02115 SN 0028-4793 J9 NEW ENGL J MED JI N. Engl. J. Med. PD JAN 24 PY 1991 VL 324 IS 4 BP 205 EP 211 DI 10.1056/NEJM199101243240401 PG 7 WC Medicine, General & Internal SC General & Internal Medicine GA EU022 UT WOS:A1991EU02200001 PM 1985241 ER PT J AU POLDER, JA BELL, DM MARTONE, WJ MARTIN, LS CURRAN, JW BENINGER, P HENDERSON, DK AF POLDER, JA BELL, DM MARTONE, WJ MARTIN, LS CURRAN, JW BENINGER, P HENDERSON, DK TI ZIDOVUDINE AFTER OCCUPATIONAL EXPOSURE TO THE HUMAN-IMMUNODEFICIENCY-VIRUS - REPLY SO NEW ENGLAND JOURNAL OF MEDICINE LA English DT Letter C1 US FDA,ROCKVILLE,MD 20857. NIH,BETHESDA,MD 20892. RP POLDER, JA (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 2 TC 0 Z9 0 U1 0 U2 0 PU MASS MEDICAL SOC PI BOSTON PA 10 SHATTUCK, BOSTON, MA 02115 SN 0028-4793 J9 NEW ENGL J MED JI N. Engl. J. Med. PD JAN 24 PY 1991 VL 324 IS 4 BP 266 EP 267 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA EU022 UT WOS:A1991EU02200014 ER PT J AU WELLS, DL HOPFENSPERGER, DJ ARDEN, NH HARMON, MW DAVIS, JP TIPPLE, MA SCHONBERGER, LB AF WELLS, DL HOPFENSPERGER, DJ ARDEN, NH HARMON, MW DAVIS, JP TIPPLE, MA SCHONBERGER, LB TI SWINE INFLUENZA-VIRUS INFECTIONS - TRANSMISSION FROM ILL PIGS TO HUMANS AT A WISCONSIN AGRICULTURAL FAIR AND SUBSEQUENT PROBABLE PERSON-TO-PERSON TRANSMISSION SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article AB In September 1988, a previously healthy 32-year-old pregnant woman was hospitalized for pneumonia and died 8 days later. The only detected was an influenza virus antigenically related to the swine influenza virus (SIV). Four days before illness onset, the patient visited a county fair swine exhibition where there was widespread influenzalike illness among the swine. To detect other persons who were possibly infected by contact with the ill swine, we measured serum SIV hemagglutination-inhibition antibody titer in 25 swine exhibitors who were 9 to 19 years old. Nineteen (76%) had SIV hemagglutination-inhibition titers of 20 or greater. Antibody was undetectable in serum samples from 25 swine exhibitors from a neighboring county. Additional studies suggest that one to three health care personnel who had contact with the patient developed influenzalike illnesses with laboratory evidence of SIV infection. An outbreak of apparent SIV infection in swine resulted in multiple human infections, and, although no recognized community outbreak resulted, there was evidence of virus transmission from the patient to health care personnel. C1 WISCONSIN DEPT HLTH & SOCIAL SERV,BUR COMMUNITY HLTH & PREVENT,MADISON,WI. WISCONSIN DEPT HLTH & SOCIAL SERV,SE REG OFF,MILWAUKEE,WI. RP WELLS, DL (reprint author), CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,MS-A32,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 25 TC 85 Z9 96 U1 0 U2 3 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD JAN 23 PY 1991 VL 265 IS 4 BP 478 EP 481 DI 10.1001/jama.265.4.478 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA ET377 UT WOS:A1991ET37700026 PM 1845913 ER PT J AU GRAVES, SR DWYER, BW MCCOLL, D MCDADE, JE AF GRAVES, SR DWYER, BW MCCOLL, D MCDADE, JE TI FLINDERS-ISLAND SPOTTED-FEVER - A NEWLY RECOGNIZED ENDEMIC FOCUS OF TICK TYPHUS IN BASS STRAIT .2. SEROLOGICAL INVESTIGATIONS SO MEDICAL JOURNAL OF AUSTRALIA LA English DT Article ID RICKETTSIA-TSUTSUGAMUSHI; BOUTONNEUSE FEVER AB Twenty-six cases of a spotted-fever-like illness have been identified on Flinders island, Tasmania, over a 17 year period. These patients and 335 healthy persons from the island were investigated serologically using the Well-Felix agglutination test (Proteus sp. antigens OX2, OX19, OXK) and rickettsia-specific microimmunofluorescence. The antigens used in these latter tests comprised one member of the typhus group (Rickettsia typhi) and three members of the spotted fever group (Rickettsia rickettsii, Rickettsia australis and Rickettsia conorii). Patients with Flinders island spotted fever showed a higher prevalence of positive reactions to the Well-Felix tests (with OX2 and OX19 antigens) and a higher prevalence of positive results to rickettsia-specific serological tests (with the exception of antibodies to Rickettsia typhi) than did healthy persons; OX2 (36% v. < 1%); OX19 (36% v. < 1%); Rickettsia rickettsii (42% v. 1%); Rickettsia australis (46% v. 1%); Rickettsia conorii (42% v. 1%); Rickettsia typhi (4% v. 4%). In seven of the 26 patients (27%) seroconversion was demonstrated by means of Weil-Felix tests, confirming recent infection. In six of these patients seroconversion was also demonstrated in rickettsia-specific tests. Although these results support the clinical evidence that the illness on Flinders Island is caused by a rickettsia of the spotted fever group, the aetiological agent remains to be isolated. C1 FAIRFIELD HOSP,DEPT CLIN PATHOL,FAIRFIELD,VIC 3078,AUSTRALIA. LAUNCESTON PATHOL,LAUNCESTON,TAS 7250,AUSTRALIA. CTR DIS CONTROL,ATLANTA,GA 30333. NR 18 TC 37 Z9 37 U1 1 U2 1 PU AUSTRALASIAN MED PUBL CO LTD PI SYDNEY PA LEVEL 1, 76 BERRY ST, SYDNEY NSW 2060, AUSTRALIA SN 0025-729X J9 MED J AUSTRALIA JI Med. J. Aust. PD JAN 21 PY 1991 VL 154 IS 2 BP 99 EP & PG 0 WC Medicine, General & Internal SC General & Internal Medicine GA EU262 UT WOS:A1991EU26200011 PM 1898756 ER PT J AU MASTRO, TD GHAFOOR, A NOMANI, NK ISHAQ, Z ANWAR, F GRANOFF, DM SPIKA, JS THORNSBERRY, C FACKLAM, RR AF MASTRO, TD GHAFOOR, A NOMANI, NK ISHAQ, Z ANWAR, F GRANOFF, DM SPIKA, JS THORNSBERRY, C FACKLAM, RR TI ANTIMICROBIAL RESISTANCE OF PNEUMOCOCCI IN CHILDREN WITH ACUTE LOWER RESPIRATORY-TRACT INFECTION IN PAKISTAN SO LANCET LA English DT Article ID STREPTOCOCCUS-PNEUMONIAE; CO-TRIMOXAZOLE; DEVELOPING-COUNTRIES; NEW-GUINEA; ETIOLOGY; VACCINE; PENICILLIN; SEROTYPES AB 87 strains of Streptococcus pneumoniae isolated during three winter seasons (1986-89) from the blood of children with acute lower respiratory tract infection (ALRI) in Pakistan were serotyped and tested for susceptibility to a range of antimicrobial agents. 97% of isolates were resistant to at least one antimicrobial drug. 62% had decreased susceptibility to co-trimoxazole (trimethoprim/sulphamethoxazole) (31% were fully resistant) and 39% were resistant to chloramphenicol. All isolates were susceptible to erythromycin, cefaclor, cephalothin, ceftriaxone, cefuroxime, rifampicin, vancomycin, and clindamycin. 29% of isolates were neither vaccine types nor vaccine-related types. Serotype distribution and antimicrobial susceptibility varied significantly during the three winter seasons. No single serotype was found in all three winters. The findings highlight the need for surveillance of antimicrobial resistance and serotype distribution of S pneumoniae in developing countries as a guide both to the choice of agent for treatment of pneumococcal infections, especially ALRI, and to the formulation of new pneumococcal conjugate vaccines for use in young children. C1 NATL INST HLTH,ISLAMABAD,PAKISTAN. WASHINGTON UNIV,SCH MED,EDWARD MALLINCKRODT DEPT PEDIAT,DIV INFECT DIS,ST LOUIS,MO 63110. CTR DIS CONTROL,CTR INFECT DIS,HOSP INFECT PROGRAM,ANTIMICROB INVEST BRANCH,ATLANTA,GA 30333. RP MASTRO, TD (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,RESP DIS BRANCH,MAILSTOP C-09,ATLANTA,GA 30333, USA. FU NIAID NIH HHS [AI-24332] NR 34 TC 94 Z9 95 U1 1 U2 2 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD JAN 19 PY 1991 VL 337 IS 8734 BP 156 EP 159 DI 10.1016/0140-6736(91)90813-5 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA ET679 UT WOS:A1991ET67900015 PM 1670799 ER PT J AU MERTZ, K SPITALNY, KC AF MERTZ, K SPITALNY, KC TI IMPORTED MALARIA ASSOCIATED WITH MALARIOTHERAPY OF LYME-DISEASE - NEW-JERSEY (REPRINTED FROM MORBIDITY AND MORTALITY WEEKLY REPORT, VOL 39, PG 873-875, 1990) SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article ID BORRELIOSIS C1 CTR DIS CONTROL,CTR INFECT DIS,DIV VECTOR BORNE INFECT DIS,BACTERIAL ZOONOSES BRANCH,ATLANTA,GA 30333. CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,MALARIA BRANCH,ATLANTA,GA 30333. RP MERTZ, K (reprint author), NEW JERSEY STATE DEPT HLTH,TRENTON,NJ 08625, USA. NR 11 TC 2 Z9 2 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD JAN 16 PY 1991 VL 265 IS 3 BP 317 EP 318 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA ER256 UT WOS:A1991ER25600007 ER PT J AU LOBEL, HO BERNARD, KW WILLIAMS, SL HIGHTOWER, AW PATCHEN, LC CAMPBELL, CC AF LOBEL, HO BERNARD, KW WILLIAMS, SL HIGHTOWER, AW PATCHEN, LC CAMPBELL, CC TI EFFECTIVENESS AND TOLERANCE OF LONG-TERM MALARIA PROPHYLAXIS WITH MEFLOQUINE - NEED FOR A BETTER DOSING REGIMEN SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article ID PLASMODIUM-FALCIPARUM; CHLOROQUINE; TRAVELERS AB To measure the effectiveness and tolerance of long-term malaria prophylaxis with mefloquine, the incidence of Plasmodium falciparum malaria and of adverse reactions was compared in Peace Corps volunteers in West Africa who took mefloquine every 2 weeks and in volunteers who took chloroquine phosphate weekly. Mefloquine was only 63% more effective than chloroquine; the monthly incidence of P falciparum infections was one case per 100 volunteers who took mefloquine and 2.7 cases per 100 volunteers who took chloroquine. Using daily proguanil (chlorguanide) hydrochloride in addition to chloroquine did not provide additional protection. All mefloquine prophylaxis failures occurred during the second week of the every-2-weeks dosing regimen in volunteers who had used mefloquine for more than 2 months. Blood concentrations of mefloquine were lower during the second week of the alternate-week regimen than during the first week, suggesting that blood levels are to low during the second week to suppress parasitemia. No serious adverse reactions were observed. The results indicate that a dosing regimen of 250 mg of mefloquine weekly should be considered for travelers to areas with chloroquine-resistant P falciparum malaria. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,STAT SERV,ATLANTA,GA 30333. OFF INT HLTH,WASHINGTON,DC. RP LOBEL, HO (reprint author), CTR DIS CONTROL,MALARIA BRANCH,ATLANTA,GA 30333, USA. NR 21 TC 65 Z9 65 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD JAN 16 PY 1991 VL 265 IS 3 BP 361 EP 364 DI 10.1001/jama.265.3.361 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA ER256 UT WOS:A1991ER25600025 PM 1984534 ER PT J AU LACKRITZ, EM LOBEL, HO HOWELL, BJ BLOLAND, P CAMPBELL, CC AF LACKRITZ, EM LOBEL, HO HOWELL, BJ BLOLAND, P CAMPBELL, CC TI IMPORTED PLASMODIUM-FALCIPARUM MALARIA IN AMERICAN TRAVELERS TO AFRICA - IMPLICATIONS FOR PREVENTION STRATEGIES SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Note AB Data from the US National Malaria Surveillance System were analyzed to assess characteristics of travelers who acquired Plasmodium falciparum infections in Africa and evaluate the impact of chloroquine resistance on the incidence of imported malaria. Although the number of cases acquired in East Africa has stabilized, the number of imported P falciparum infections acquired in West Africa increased threefold from 1985 to 1988, and the proportion of travelers who reported failure of chloroquine prophylaxis increased from 10% to 48%. Fifty-eight percent of patients who acquired malaria in West Africa had not used chemoprophylaxis. To curb the rising incidence of P falciparum infections in American travelers, the Centers for Disease Control revised malaria prophylaxis recommendations to include the use of mefloquine in areas of chloroquine resistance. Use of malaria protection measures by travelers to West Africa must also be improved. RP LACKRITZ, EM (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,MALARIA BRANCH,MAILSTOP F-12,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 14 TC 40 Z9 42 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD JAN 16 PY 1991 VL 265 IS 3 BP 383 EP 385 DI 10.1001/jama.265.3.383 PG 3 WC Medicine, General & Internal SC General & Internal Medicine GA ER256 UT WOS:A1991ER25600030 PM 1984539 ER PT J AU MUDER, RR BRENNEN, C WAGENER, MM VICKERS, RM RIHS, JD HANCOCK, GA YEE, YC MILLER, JM YU, VL AF MUDER, RR BRENNEN, C WAGENER, MM VICKERS, RM RIHS, JD HANCOCK, GA YEE, YC MILLER, JM YU, VL TI METHICILLIN-RESISTANT STAPHYLOCOCCAL COLONIZATION AND INFECTION IN A LONG-TERM CARE FACILITY SO ANNALS OF INTERNAL MEDICINE LA English DT Article ID AUREUS NASAL CARRIAGE; NOSOCOMIAL INFECTIONS; NURSING-HOMES; STRAIN; CIPROFLOXACIN; HEMODIALYSIS; PROPHYLAXIS; OUTBREAK AB Objective: To determine the natural history of colonization by methicillin-resistant Staphylococcus aureus (MRSA) among patients in a long-term care facility. We specifically sought to determine if MRSA colonization was predictive of subsequent infection. Design: Cohort study. Setting: Long-term Veterans Affairs Medical Center. Patients: A total of 197 patients residing on two units were followed with regular surveillance cultures of the anterior nares. Main Outcome Measurement: The development of staphylococcal infection. Results: Thirty-two patients were persistent carriers of MRSA and 44 were persistent carriers of methicillin-susceptible strains (MSSA). Twenty-five percent of MRSA carriers had an episode of staphylococcal infection compared with 4% of MSSA carriers and 4.5% of non-carriers (P < 0.01; relative risk 3.8%; 95% CI, 2.0 to 6.4). The rate of development of infection among MRSA carriers was 15% for every 100 days of carriage. Using logistic regression analysis, persistent MRSA carriage was the most significant predictor of infection (P < 0.001; odds ratio, 3.7). Seventy-three percent of all MRSA infections occurred among MRSA carriers. Isolates of MRSA from 7 patients were typed. Colonizing and infecting strains had the same phage type in all 7 patients and the same pattern of plasmid EcoRI restriction endonuclease fragments in 5 patients. Conclusions: Colonization of the anterior nares by MRSA predicts the development of staphylococcal infection in long-term care patients; most infections arise from endogenously carried strains. Colonization by MRSA indicates a significantly greater risk for infection than does colonization by MSSA. The results offer a theoretic rationale for reduction in MRSA infections by interventions aimed at eliminating the carrier state. C1 UNIV PITTSBURGH,SCH MED,PITTSBURGH,PA 15261. CTR DIS CONTROL,ATLANTA,GA 30333. RP MUDER, RR (reprint author), PITTSBURGH VET AFFAIRS MED CTR,INFECT DIS SECT,UNIV DR C,PITTSBURGH,PA 15240, USA. NR 33 TC 287 Z9 288 U1 1 U2 6 PU AMER COLL PHYSICIANS PI PHILADELPHIA PA INDEPENDENCE MALL WEST 6TH AND RACE ST, PHILADELPHIA, PA 19106-1572 SN 0003-4819 J9 ANN INTERN MED JI Ann. Intern. Med. PD JAN 15 PY 1991 VL 114 IS 2 BP 107 EP 112 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA ER534 UT WOS:A1991ER53400002 PM 1984384 ER PT J AU RICHET, HM CRAVEN, PC BROWN, JM LASKER, BA COX, CD MCNEIL, MM TICE, AD JARVIS, WR TABLAN, OC AF RICHET, HM CRAVEN, PC BROWN, JM LASKER, BA COX, CD MCNEIL, MM TICE, AD JARVIS, WR TABLAN, OC TI A CLUSTER OF RHODOCOCCUS (GORDONA) BRONCHIALIS-STERNAL WOUND INFECTIONS AFTER CORONARY-ARTERY BYPASS-SURGERY SO NEW ENGLAND JOURNAL OF MEDICINE LA English DT Note ID CORYNEBACTERIUM EQUI; IDENTIFICATION; ENDOPHTHALMITIS; AURANTIACUS; GENUS; AIDS C1 CTR DIS CONTROL,CTR INFECT DIS,DIV MYCOT DIS,ATLANTA,GA 30333. INFECT LTD,TACOMA,WA. RP RICHET, HM (reprint author), CTR DIS CONTROL,CTR INFECT DIS,HOSP INFECT PROGRAM,MAILSTOP C10,ATLANTA,GA 30333, USA. NR 34 TC 65 Z9 65 U1 0 U2 1 PU MASS MEDICAL SOC PI BOSTON PA 10 SHATTUCK, BOSTON, MA 02115 SN 0028-4793 J9 NEW ENGL J MED JI N. Engl. J. Med. PD JAN 10 PY 1991 VL 324 IS 2 BP 104 EP 109 DI 10.1056/NEJM199101103240206 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA EQ977 UT WOS:A1991EQ97700006 PM 1984175 ER PT J AU HIERHOLZER, JC MOORE, P BROOME, CV AF HIERHOLZER, JC MOORE, P BROOME, CV TI MYCOPLASMA AND EPIDEMIC GROUP-A MENINGOCOCCAL MENINGITIS - REPLY SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Letter RP HIERHOLZER, JC (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. RI Moore, Patrick/F-3960-2011 OI Moore, Patrick/0000-0002-8132-858X NR 4 TC 2 Z9 2 U1 0 U2 1 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD JAN 9 PY 1991 VL 265 IS 2 BP 212 EP 212 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EQ602 UT WOS:A1991EQ60200019 ER PT J AU BECERRA, JE HOGUE, CJR ATRASH, HK PEREZ, N AF BECERRA, JE HOGUE, CJR ATRASH, HK PEREZ, N TI INFANT-MORTALITY AMONG HISPANICS - A PORTRAIT OF HETEROGENEITY SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article ID UNITED-STATES; STANDARDIZED TERMINOLOGY; MEXICAN-AMERICAN; WOMEN; POPULATIONS; LATINO; HEALTH; BIRTH AB In the United States, infant mortality risks among Hispanics have not been previously evaluated at the nation level. We used the 1983 and 1984 national Linked Birth and Infant Death data sets to compare infant mortality risks among single-delivery infants of Hispanic descent with those among single-delivery infants of non-Hispanic whites (the reference group). We also included the 1983 and 1984 linked birth cohort for single-delivery infants in Puerto Rico. Among all Hispanic groups, the neonatal (< 28 days) mortality risk was higher among Puerto Rican islanders (relative risk ]RR[ = 2.3) and continental Puerto Ricans (RR = 1.5) and lower among Cuban-Americans (RR = 1.0) and Mexican-Americans (RR = 1.0). The postneonatal mortality risk (28 to 364 days) was highest among continental Puerto Ricans (RR = 1.2) and lowest among Cuban-Americans (RR = 0.6). Our study underscores the heterogeneity of the Hispanic population in the United States and suggests that interventions to prevent infant mortality be tailored to ethnic-specific risk factors and outcomes. C1 COMMONWEALTH PUERTO RICO DEPT HLTH,OFF HLTH STAT,SAN JUAN,PR. RP BECERRA, JE (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV REPROD HLTH,ATLANTA,GA 30333, USA. RI Becerra, Jose/C-4071-2014 NR 35 TC 119 Z9 119 U1 0 U2 2 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD JAN 9 PY 1991 VL 265 IS 2 BP 217 EP 221 DI 10.1001/jama.265.2.217 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA EQ602 UT WOS:A1991EQ60200028 PM 1984150 ER PT J AU KLINE, RL BROTHERS, T HALSEY, N BOULOS, R LAIRMORE, MD QUINN, TC AF KLINE, RL BROTHERS, T HALSEY, N BOULOS, R LAIRMORE, MD QUINN, TC TI EVALUATION OF ENZYME IMMUNOASSAYS FOR ANTIBODY TO HUMAN T-LYMPHOTROPIC VIRUSES TYPE-I/II SO LANCET LA English DT Article ID CELL LEUKEMIA-VIRUS; CHRONIC PROGRESSIVE MYELOPATHY; HTLV-I; LYMPHOMA VIRUS; BLOOD; TRANSMISSION; INFECTION; ANTIGEN AB To evaluate the sensitivity and specificity of HTLV-I/II assays, serum from 1100 pregnant Haitian women was tested with seven commercially available HTLV I/II assays. Serum that was found to be reactive in any assay was analysed by western blot and all indeterminate samples were further characterised by radioimmunoprecipitation assays (RIPA). 59 (5.4%) samples were HTLVI/II antibody positive by western blot and/or RIPA. The sensitivity of these seven assays ranged from 93.2% to 100%, with the 'Recombinant HTLV-I' (Cambridge Bioscience) and 'Serodia' HTLV-I' (Fujirebio) assays having the highest sensitivity (100%). The specificity of these assays ranged from 98.4% to 100%, with the Abbott assay having the highest specificity (99.5%), 100%) according to two different methods of evaluation. Whether the antigens used in any assay were whole disrupted virus or recombinant gene products made no difference. The low positive predictive values of some of these assays (71.8-91.7%), even in a high prevalence population, and the need for RIPA to test indeterminate sera, indicate that for routine screening of blood donors there is still room for improvement both in screening and confirmatory assays for HTLV-I/II. C1 NIAID,IMMUNOREGULAT LAB,BETHESDA,MD 20892. JOHNS HOPKINS UNIV,SCH MED,DIV INFECT DIS,BALTIMORE,MD 21205. JOHNS HOPKINS UNIV,SCH HYG & PUBL HLTH,DEPT INT HLTH,BALTIMORE,MD 21218. CTR DEV & HLTH,PORT AU PRINCE,HAITI. CTR DIS CONTROL,RETROVIRUS DIS BRANCH,ATLANTA,GA 30333. FU PHS HHS [R0IA126521] NR 25 TC 25 Z9 26 U1 0 U2 0 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD JAN 5 PY 1991 VL 337 IS 8732 BP 30 EP 33 DI 10.1016/0140-6736(91)93343-8 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA EQ604 UT WOS:A1991EQ60400017 PM 1670658 ER PT J AU THACKER, SB BANTA, HD AF THACKER, SB BANTA, HD TI TECHNOLOGY-ASSESSMENT AND THE FEAR OF LITIGATION - REPLY SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Letter C1 NETHERLANDS ORG APPL SCI RES,THE HAGUE,NETHERLANDS. RP THACKER, SB (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 4 TC 0 Z9 0 U1 0 U2 1 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD JAN 2 PY 1991 VL 265 IS 1 BP 29 EP 29 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EP555 UT WOS:A1991EP55500022 ER PT B AU SHEALY, DB HILL, RH ORTI, DL BAILEY, SL MILLER, BB TURNER, WE AF SHEALY, DB HILL, RH ORTI, DL BAILEY, SL MILLER, BB TURNER, WE BE STRIMAITIS, JR LITTLE, JN TI AUTOMATED SAMPLE PREPARATION OF SERUM COTININE FOR GC/MS ANALYSIS SO ADVANCES IN LABORATORY AUTOMATION ROBOTICS, VOL 7 SE ADVANCES IN LABORATORY AUTOMATION ROBOTICS LA English DT Proceedings Paper CT 8TH INTERNATIONAL SYMP ON LABORATORY ROBOTICS CY SEP 16-19, 1990 CL BOSTON, MA RP SHEALY, DB (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. RI Barr, Dana/E-6369-2011; Barr, Dana/E-2276-2013 NR 0 TC 0 Z9 0 U1 0 U2 0 PU ZYMARK CORP PI HOPKINTON PA HOPKINTON BN 0-931565-06-5 J9 ADV LAB AUT PY 1991 BP 533 EP 544 PG 12 WC Energy & Fuels; Medical Laboratory Technology; Pharmacology & Pharmacy SC Energy & Fuels; Medical Laboratory Technology; Pharmacology & Pharmacy GA BT90W UT WOS:A1991BT90W00034 ER PT J AU HEITBRINK, WA BARON, PA WILLEKE, K AF HEITBRINK, WA BARON, PA WILLEKE, K TI COINCIDENCE IN TIME-OF-FLIGHT AEROSOL SPECTROMETERS - PHANTOM PARTICLE CREATION SO AEROSOL SCIENCE AND TECHNOLOGY LA English DT Article ID SIZER APS 3300 AB When using time-of-flight aerosol spectrometers, particle size measurement is based upon a particle's transit time between two laser beams. The particle's transit time is assumed to be the time difference between the two pulses of light that are produced as the particle passes through the two laser beams. Particle coincidence, which occurs when a second particle crosses the first laser beam before the first particle crosses the second laser beam, has a complex effect upon the measured size distribution. As a result of coincidence, time-of-flight aerosol spectrometers can replace real particles of one size with spurious, or phantom, particles of a different size in the measured distribution. When partial detection of a particle occurs, i.e., only one pulse from a particle is detected, another particle producing a pulse that occurs while the timer is open can cause the recording of a randomly sized phantom particle. The creation of these phantom particles, which we termed "open-timer" phantom particles, has been investigated theoretically and experimentally in a commercially available time-of-flight aerosol spectrometer. The number of these open-timer phantom particles was found to increase with particle size and aerosol concentration. In addition, the instrument's detection logic affects the number and size of the phantom particles. These are most apparent in the tails and minima of the measured distribution. In order to minimize phantom particle creation, the concentration of partially detected particles must be minimized. Strategies to reduce phantom particle concentration involve reducing the concentration of small particles near the optical detection threshold of the spectrometer. C1 UNIV CINCINNATI,DEPT ENVIRONM HLTH,AEROSOL RES LAB,CINCINNATI,OH 45267. RP HEITBRINK, WA (reprint author), NIOSH,CTR DIS CONTROL,DIV PHYS SCI & ENGN,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 13 TC 33 Z9 33 U1 1 U2 2 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0278-6826 J9 AEROSOL SCI TECH JI Aerosol Sci. Technol. PY 1991 VL 14 IS 1 BP 112 EP 126 DI 10.1080/02786829108959476 PG 15 WC Engineering, Chemical; Engineering, Mechanical; Environmental Sciences; Meteorology & Atmospheric Sciences SC Engineering; Environmental Sciences & Ecology; Meteorology & Atmospheric Sciences GA EP726 UT WOS:A1991EP72600011 ER PT J AU KAMENGA, M RYDER, RW JINGU, M MBUYI, N MBU, L BEHETS, F BROWN, C HEYWARD, WL AF KAMENGA, M RYDER, RW JINGU, M MBUYI, N MBU, L BEHETS, F BROWN, C HEYWARD, WL TI EVIDENCE OF MARKED SEXUAL-BEHAVIOR CHANGE ASSOCIATED WITH LOW HIV-1 SEROCONVERSION IN 149 MARRIED-COUPLES WITH DISCORDANT HIV-1 SEROSTATUS - EXPERIENCE AT AN HIV COUNSELING-CENTER IN ZAIRE SO AIDS LA English DT Article DE ZAIRE; HIV-1; COUNSELING; SEROLOGY ID HUMAN IMMUNODEFICIENCY VIRUS; AFRICA; TRANSMISSION; EPIDEMIOLOGY; INFECTION AB To determine the effect of an HIV-1 counselling program on 149 married Zairian couples with discordant HIV-1 serology, the rates of HIV-1 seroconversion and reported condom utilization have been observed during 382.4 person-years of follow-up (minimum follow-up time per couple of 6 months). Before determination of HIV-1 serostatus and counselling, less than 5% of these couples had ever used a condom. One month after notification of HIV-1 serostatus and counselling, 70.7% of couples reported using condoms during all episodes of sexual intercourse. At 18 months follow-up, 77.4% of the 140 couples still being followed reported continued use of condoms during all episodes of sexual intercourse. At the time of notification of HIV-1 serostatus, 18 couples experienced acute psychological distress. Home-based counselling by trained nurses resolved these difficulties in all but three couples who subsequently divorced. Intensive counselling following notification of HIV-1 serostatus led to low rates of HIV-1 seroconversion (3.1% per 100 person-years of observation) in Zairian married couples with discordant HIV-1 serostatus who voluntarily attended an HIV counselling center. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,ATLANTA,GA 30333. NIAID,BETHESDA,MD 20892. RP KAMENGA, M (reprint author), DEPT PUBL HLTH,PROJET SIDA,KINSHASA,ZAIRE. NR 13 TC 196 Z9 197 U1 2 U2 5 PU RAPID SCIENCE PUBLISHERS PI LONDON PA 2-6 BOUNDARY ROW, LONDON, ENGLAND SE1 8NH SN 0269-9370 J9 AIDS JI Aids PD JAN PY 1991 VL 5 IS 1 BP 61 EP 67 PG 7 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA FA037 UT WOS:A1991FA03700009 PM 2059362 ER PT J AU OBRIEN, TR POLON, C SCHABLE, CA VANDEVANTER, N RAYFIELD, MA WALLACE, D STUART, A HOLMBERG, SD AF OBRIEN, TR POLON, C SCHABLE, CA VANDEVANTER, N RAYFIELD, MA WALLACE, D STUART, A HOLMBERG, SD TI HIV-2 INFECTION IN AN AMERICAN SO AIDS LA English DT Note DE HIV-2; AIDS; SURVEILLANCE; UNITED-STATES; EPIDEMIOLOGY ID IMMUNODEFICIENCY VIRUS TYPE-2; POLYMERASE CHAIN-REACTION; WEST-AFRICA; AIDS; RETROVIRUS; PREVALENCE; MORTALITY; ANTIBODY; BISSAU AB HIV-2 is endemic in West Africa but rare elsewhere. In the USA there have been 18 reported cases of HIV-2 infection; most identified people have been West Africans. We recently diagnosed the first case of HIV-2 infection in a native-born US citizen, a woman whose serum was found to be reactive to anti-HIV-1 enzyme immunoassay (EIA) when she attempted to donate blood in 1986. Although both HIV-1- and HIV-2-specific EIAs were reactive, the anti-HIV-2 Western blot (WB) was positive, while the anti-HIV-1 WB was positive or indeterminate on different occasions. Synthetic peptide testing was reactive for HIV-2 but not HIV-1. HIV-2 DNA was detected using the polymerase chain reaction procedure. Although she had travelled to West Africa, it is unclear how she became infected with HIV-2. C1 ORTHO DIAGNOST SYST INC,RARITAN,NJ. COLUMBIA UNIV,SCH PUBL HLTH,DIV SOCIOMED SCI,NEW YORK,NY 10027. RP OBRIEN, TR (reprint author), CTR DIS CONTROL,DIV HIV AIDS,ATLANTA,GA 30333, USA. NR 25 TC 16 Z9 16 U1 0 U2 0 PU RAPID SCIENCE PUBLISHERS PI LONDON PA 2-6 BOUNDARY ROW, LONDON, ENGLAND SE1 8NH SN 0269-9370 J9 AIDS JI Aids PD JAN PY 1991 VL 5 IS 1 BP 85 EP 88 PG 4 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA FA037 UT WOS:A1991FA03700012 PM 2059365 ER PT J AU BROWN, C KLINE, R ATIBU, L FRANCIS, H RYDER, R QUINN, TC AF BROWN, C KLINE, R ATIBU, L FRANCIS, H RYDER, R QUINN, TC TI PREVALENCE OF HIV-1 P24 ANTIGENEMIA IN AFRICAN AND NORTH-AMERICAN POPULATIONS AND CORRELATION WITH CLINICAL STATUS SO AIDS LA English DT Note DE HIV-1 INFECTION; P24 ANTIGEN; AIDS; AFRICAN POPULATIONS; NORTH AMERICAN POPULATIONS ID IMMUNODEFICIENCY VIRUS-INFECTION; AIDS; ANTIBODIES; SERUM AB Sera from 622 individuals and culture supernatants from three HIV-1 viral isolates were assayed for HIV-1 p24 antigen to investigate the frequency of p24 antigenemia in African and North American populations using three commercial HIV-1 p24 antigen assays (Coulter, Du Pont, and Abbott). The prevalence of p24 antigenemia in 89 hospitalized Zairian AIDS patients was significantly lower than in 47 clinically comparable AIDS patients in the USA (17 versus 48%, P < 0.0001). Prevalence of p24 antigenemia in sera from 200 asymptomatic HIV-1-infected individuals was also lower in individuals from Zaire compared with 83 individuals in the USA (3.5 versus 7%). In African individuals, antigenemia prevalence increased with advanced clinical status: 8% in ambulatory AIDS patients, 17% in hospitalized AIDS patients and 18% in postmortem AIDS patients. Acid hydrolysis treatment of sera from 63 Zairian AIDS patients initially negative for p24 antigen showed an 11% positivity rate confirmed by neutralization, suggesting that immune complexing of p24 antigen may play a role in the observed lower p24 antigenemia rates reported for African individuals. C1 JOHNS HOPKINS UNIV,DIV INFECT DIS,BLALOCK 1111,600 N WOLFE ST,BALTIMORE,MD 21205. PROJET SIDA,KINSHASA,ZAIRE. CTR DIS CONTROL,ATLANTA,GA 30333. NIAID,IMMUNOREGULAT LAB,BETHESDA,MD 20892. NR 14 TC 28 Z9 28 U1 0 U2 0 PU RAPID SCIENCE PUBLISHERS PI LONDON PA 2-6 BOUNDARY ROW, LONDON, ENGLAND SE1 8NH SN 0269-9370 J9 AIDS JI Aids PD JAN PY 1991 VL 5 IS 1 BP 89 EP 92 PG 4 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA FA037 UT WOS:A1991FA03700013 PM 1905553 ER PT J AU DECOCK, KM BRUNVEZINET, F SORO, B AF DECOCK, KM BRUNVEZINET, F SORO, B TI HIV-1 AND HIV-2 INFECTIONS AND AIDS IN WEST-AFRICA SO AIDS LA English DT Article DE AFRICA; WEST AFRICA; AIDS; HIV-1; HIV-2 ID SIMIAN IMMUNODEFICIENCY VIRUS; IVORY-COAST; ABIDJAN; PROTECTION; VACCINE; GAMBIA C1 PROJET RETRO CL,ABIDJAN,COTE IVOIRE. INST NATL SANTE PUBL,ABIDJAN,COTE IVOIRE. CTR DIS CONTROL,NATL CTR INFECT DIS,DIV HIV AIDS,ATLANTA,GA 30333. HOP CLAUDE BERNARD,VIROL LAB,F-75994 PARIS 19,FRANCE. NR 69 TC 41 Z9 42 U1 0 U2 0 PU RAPID SCIENCE PUBLISHERS PI LONDON PA 2-6 BOUNDARY ROW, LONDON, ENGLAND SE1 8NH SN 0269-9370 J9 AIDS JI Aids PY 1991 VL 5 SU 1 BP S21 EP S28 PG 8 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA LZ440 UT WOS:A1991LZ44000004 PM 1669921 ER PT J AU RECKER, DP KULAGA, H DORSETT, D FOLKS, T KINDT, TJ AF RECKER, DP KULAGA, H DORSETT, D FOLKS, T KINDT, TJ TI A MONOCYTE-DERIVED FACTOR INTERFERES WITH DETECTION OF REVERSE-TRANSCRIPTASE IN HIV-1 INFECTION SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Article ID HUMAN IMMUNODEFICIENCY VIRUS; DEPENDENT DNA POLYMERASE; HTLV-III; T-CELL; RETROVIRUS; AIDS; LAV; RECEPTOR; VIRIONS; LINES AB Culture supernatants from the rabbit macrophage cell line 6083 infected with a retrovirus, human immunodeficiency virus type 1 (HIV-1), were negative for reverse transcriptase (RT) expression although the line was shown to be productively infected by all other criteria tested. Supernatants from uninfected cultures of 6083, the human monocyte line U937, and from freshly isolated peripheral human monocytes, were found to contain a monocyte-derived inhibitory factor (MDIF) which interferes with a standard assay for RT. MDIF is a heat-labile activity of approximately of 40 kD. Both substrates and products of the reverse transcriptase assay are degraded by MDIF which is not affected by reduction and alkylation of disulfide bonds. MDIF is inhibited by the addition of a particular thioated oligonucleotide (S-dG30) to the reaction mixture but this addition also inhibits RT. The optimum method to minimize MDIF interference in the RT assay is by addition of ethylene glycol bis-(beta-aminoethyl ether) N,N,N',N'-tetraacetic acid (EGTA); MDIF requires divalent cations for activity and has a strong preference for calcium which is preferentially chelated by EGTA. The potential presence of this inhibitory activity should be conisdered when using RT levels as a measure of retroviral infection. C1 NIAID,IMMUNOGENET LAB,TWINBROOK FACIL,12441 PARKLAWN DR,BETHESDA,MD 20892. NIMH,NEUROPSYCHIAT BRANCH,WASHINGTON,DC 20032. EMORY UNIV,SCH MED,DEPT PATHOL,ATLANTA,GA 30322. CTR DIS CONTROL,RETROVIRUS DIS BRANCH,ATLANTA,GA 30333. NR 23 TC 8 Z9 8 U1 0 U2 0 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PD JAN PY 1991 VL 7 IS 1 BP 73 EP 81 PG 9 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA EY676 UT WOS:A1991EY67600009 PM 1707643 ER PT J AU ATKINSON, WL AF ATKINSON, WL TI MEASLES RETURNS SO AMERICAN FAMILY PHYSICIAN LA English DT Editorial Material RP ATKINSON, WL (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,DIV IMMUNIZAT,ATLANTA,GA 30333, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER ACAD FAMILY PHYSICIANS PI KANSAS CITY PA 8880 WARD PARKWAY, KANSAS CITY, MO 64114-2797 SN 0002-838X J9 AM FAM PHYSICIAN JI Am. Fam. Physician PD JAN PY 1991 VL 43 IS 1 BP 104 EP & PG 0 WC Primary Health Care; Medicine, General & Internal SC General & Internal Medicine GA ER561 UT WOS:A1991ER56100007 PM 1986482 ER PT J AU DECOUFLE, P HOLMGREEN, P CALLE, EE WEEKS, MF AF DECOUFLE, P HOLMGREEN, P CALLE, EE WEEKS, MF TI NONRESPONSE AND INTENSITY OF FOLLOW-UP IN AN EPIDEMIOLOGIC-STUDY OF VIETNAM-ERA VETERANS SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Article DE BIAS; EPIDEMIOLOGIC METHODS; FOLLOW-UP STUDIES ID RESPONDENTS; BIAS; MAIL AB Characteristics of nonrespondents, respondents who were easy to locate, and respondents who were hard to locate were examined with the use of data from a telephone healthy survey of male, US Army, vietnam-era veterans, Of 17,867 eligible men discharged from active military duty in the late 1960s and early 1970s, 15,288 (86%) were successfully located and interviewed during 1985-1986. Veterans who could not be located were more likely than respondents to possess baseline characteristics predictive of increased mortality. In contrast, subjects who were located but refused to be interviewed were similar to respondents. Among veterans who were interviewed, those who were hardest to locate had the highest prevalence of known risk factors for diminished health status and reported many health problems with higher relative frequencies than respondents who were easier to locate. Odds ratios comparing the prevalence of each of 11 health outcomes in men who had served in Vietnam with that in men who had served in Vietnam with that in men who had served elsewhere did not vary appreciably by intensity of follow-up. In particular, the subgroup of respondents that was located and interviewed within 2 weeks of initiation of follow-up (comprising 25% of all respondent) produced odds ratios for 10 of the 11 outcomes that were not appreciably different from odds ratios based on all respondents. C1 RES TRIANGLE INST,RES TRIANGLE PK,NC 27709. RP DECOUFLE, P (reprint author), CTR DIS CONTROL F37,CTR ENVIRONM HLTH & INJURY CONTROL,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 20 TC 20 Z9 20 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD JAN 1 PY 1991 VL 133 IS 1 BP 83 EP 95 PG 13 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EP704 UT WOS:A1991EP70400012 PM 1983902 ER PT J AU TYLER, CW LEE, NC ROBBOY, SJ KURMAN, RJ PARIS, AL WINGO, PA WILLIAMSON, GD AF TYLER, CW LEE, NC ROBBOY, SJ KURMAN, RJ PARIS, AL WINGO, PA WILLIAMSON, GD TI THE DIAGNOSIS OF OVARIAN-CANCER BY PATHOLOGISTS - HOW OFTEN DO DIAGNOSES BY CONTRIBUTING PATHOLOGISTS AGREE WITH A PANEL OF GYNECOLOGIC PATHOLOGISTS SO AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY LA English DT Article DE OVARIAN NEOPLASMS; DIAGNOSIS; PREDICTIVE VALUE OF TESTS; PATHOLOGY AB The Cancer and Steroid Hormone Study, a multicenter, population-based, case-control study of ovarian, breast, and endometrial cancer in women 20 to 54 years of age, permitted the diagnoses of contributing pathologists to be compared with those of a panel of three gynecologic pathologists. A diagnosis of ovarian cancer was made by contributing pathologists on 477 subjects. Agreement between the two groups of pathologists was 97% for primary epithelial ovarian cancer and 89% for primary nonepithelial ovarian malignancies. Agreement on diagnosis of major cellular subtypes of ovarian malignancy ranged between 73% for endometrioid cancer and 100% for clear cell carcinomas. We conclude that the diagnosis of pathologic features of primary ovarian cancer is highly predictable. Nonetheless, diagnosis by histologic type varies sufficiently that a review process should be considered for clinical or investigative decisions involving specific histologic diagnoses of ovarian cancer. C1 OZARKS MED CTR,DEPT PATHOL,W PLAINS,MO. CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,ATLANTA,GA 30333. UNIV MED & DENT NEW JERSEY,NEW JERSEY MED SCH,DEPT PATHOL,NEWARK,NJ 07103. CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333. JOHNS HOPKINS UNIV HOSP,DEPT GYNECOL OBSTET,BALTIMORE,MD 21205. JOHNS HOPKINS UNIV HOSP,DEPT PATHOL,BALTIMORE,MD 21205. CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,ATLANTA,GA 30333. RP TYLER, CW (reprint author), CTR DIS CONTROL,OFF DIRECTOR,MAILSTOP E-42,ATLANTA,GA 30333, USA. FU NICHD NIH HHS [3-Y01-HD-8-1037] NR 13 TC 34 Z9 34 U1 0 U2 0 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0002-9378 J9 AM J OBSTET GYNECOL JI Am. J. Obstet. Gynecol. PD JAN PY 1991 VL 164 IS 1 BP 65 EP 70 PN 1 PG 6 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA ET500 UT WOS:A1991ET50000016 PM 1986629 ER PT J AU ZENKER, PN BERMAN, SM AF ZENKER, PN BERMAN, SM TI CONGENITAL-SYPHILIS CRITERIA - REPLY SO AMERICAN JOURNAL OF PUBLIC HEALTH LA English DT Letter RP ZENKER, PN (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,DIV STD HIV PREVENT,ATLANTA,GA 30333, USA. NR 7 TC 1 Z9 1 U1 0 U2 0 PU AMER PUBLIC HEALTH ASSN INC PI WASHINGTON PA 1015 FIFTEENTH ST NW, WASHINGTON, DC 20005 SN 0090-0036 J9 AM J PUBLIC HEALTH JI Am. J. Public Health PD JAN PY 1991 VL 81 IS 1 BP 111 EP 112 DI 10.2105/AJPH.81.1.111-a PG 2 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EY429 UT WOS:A1991EY42900023 ER PT J AU RICHARDS, FO EBERHARD, ML BRYAN, RT MCNEELEY, DF LAMMIE, PJ MCNEELEY, MB BERNARD, Y HIGHTOWER, AW SPENCER, HC AF RICHARDS, FO EBERHARD, ML BRYAN, RT MCNEELEY, DF LAMMIE, PJ MCNEELEY, MB BERNARD, Y HIGHTOWER, AW SPENCER, HC TI COMPARISON OF HIGH-DOSE IVERMECTIN AND DIETHYLCARBAMAZINE FOR ACTIVITY AGAINST BANCROFTIAN FILARIASIS IN HAITI SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID WUCHERERIA-BANCROFTI; EFFICACY; ONCHOCERCIASIS; INFECTION; CITRATE; THERAPY AB This three-phase study was designed to compare high dose ivermectin with a standard diethylcarbamazine (DEC) regimen for patient tolerability, potential to kill adult filaria, and duration of microfilarial suppression in 30 Haitian subjects with Wuchereria bancrofti microfilaremia. All were first given a 1-mg oral dose of ivermectin (phase 1) to reduce microfilaria densities. Participants were randomized into three groups: Group 1 received DEC (6mg/kg per day for 12 days), Group 2 received 200 mcg/kg of ivermectin, and Group 3 received 400 mcg/kg of ivermectin (200 mcg/kg per day for 2 days). All drug regimens were well tolerated with few adverse reactions. Most reactions occurred during phase I and consisted primarily of headache, fever, and myalgia. At the end of phase 1, 27 of 30 (90%) patients were microfilaria negative. During phase 2, four of the six men receiving DEC developed scrotal reactions suggesting killing adult worms; no such reactions were noted in 10 men receiving ivermectin (p < 0.05). At one-year follow up (phase 3), all treatment groups had less than 10% return to pretreatment microfilaria levels. The mean percent of baseline microfilaria counts were for Group 1, 0.9% (range 0-5%); Group 2, 8.2% (range 0-31%); and Group 3, 3.8% (range 0-25%). Seven individuals in Group 1 were microfilaria-negative, while only one and three individuals were microfilaria-negative in Groups 2 and 3, respectively. These results suggest that DEC causes more damage to the adult worms and greater reduction in microfilaria densities than ivermectin, but that high doses of ivermectin may suppress microfilaremia in lymphatic filariasis for periods much longer than previously reported. C1 HOSP ST CROIX LEOGANE,PORT AU PRINCE,HAITI. RP RICHARDS, FO (reprint author), CTR DIS CONTROL,DIV PARASIT DIS,ATLANTA,GA 30333, USA. NR 26 TC 58 Z9 58 U1 0 U2 2 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD JAN PY 1991 VL 44 IS 1 BP 3 EP 10 PG 8 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA EY659 UT WOS:A1991EY65900001 PM 1996738 ER PT J AU COLLINS, WE ANDERS, RF RUEBUSH, TK KEMP, DJ WOODROW, GC CAMPBELL, GH BROWN, GV IRVING, DO GOSS, N FILIPSKI, VK COPPEL, RL BRODERSON, JR THOMAS, LM PYE, D SKINNER, JC WILSON, C STANFILL, PS PROCELL, PM AF COLLINS, WE ANDERS, RF RUEBUSH, TK KEMP, DJ WOODROW, GC CAMPBELL, GH BROWN, GV IRVING, DO GOSS, N FILIPSKI, VK COPPEL, RL BRODERSON, JR THOMAS, LM PYE, D SKINNER, JC WILSON, C STANFILL, PS PROCELL, PM TI IMMUNIZATION OF OWL MONKEYS WITH THE RING-INFECTED ERYTHROCYTE SURFACE-ANTIGEN OF PLASMODIUM-FALCIPARUM SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID VIVAX AB Aotus nancymai were immunized with the 4-mer, 8-mer, and 11-mer repeat peptides of the ring-infected erythrocyte surface antigen molecule of Plasmodium falciparum conjugated to diphtheria toxoid with muramyl dipeptide (MDP) as adjuvant. Immunization failed to induce protective immunity against the Uganda Palo Alto strain of P. falciparum as judged by maximum levels of parasitemia of immunized monkeys relative to those of controls. The fused polypeptide FPAg632, when combined with MDP, also failed to induce protective immunity. However, the maximum level of parasitemia and serologic response to the 11-mer peptide were inversely correlated. The safety of the use of MDP was evident. C1 CTR DIS CONTROL,SCI RESOURCES PROGRAM,ATLANTA,GA 30333. ROYAL MELBOURNE HOSP,WALTER & ELIZA HALL INST MED RES,PARKVILLE,VIC 3050,AUSTRALIA. BIOTECHNOL AUSTRALIA PTY LTD,ROSEVILLE,NSW 2069,AUSTRALIA. COMMONWEALTH SERUM LABS,PARKVILLE,VIC 3052,AUSTRALIA. RP COLLINS, WE (reprint author), CTR DIS CONTROL,DIV PARASIT DIS,ATLANTA,GA 30333, USA. RI Coppel, Ross/A-6626-2008 OI Coppel, Ross/0000-0002-4476-9124 NR 9 TC 39 Z9 39 U1 0 U2 0 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD JAN PY 1991 VL 44 IS 1 BP 34 EP 41 PG 8 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA EY659 UT WOS:A1991EY65900006 PM 1996739 ER PT J AU ABAZA, SM SULLIVAN, JJ VISVESVARA, GS AF ABAZA, SM SULLIVAN, JJ VISVESVARA, GS TI ISOENZYME PROFILES OF 4 STRAINS OF GIARDIA-LAMBLIA AND THEIR INFECTIVITY TO JIRDS SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID MONGOLIAN GERBILS; TYI-S-33 MEDIUM; ELECTROPHORESIS AB The infectivity to jirds (Meriones unguiculatus) and the cyst excretion pattern of a recently isolated strain of Giardia lamblia from Egypt, Strain CDC:1088:1(EGY), were compared to those of three well-established strains. All five jirds inoculated orally with strain UNO:0487:1 (UNO) became infected and began excreting cysts 3-6 days post-infection (dpi); no cysts were detected between 8-12 dpi after which time cysts were produced through day 19. Four of the five jirds infected with Strain ATCC:30957 (WB) and three of the five jirds infected with strain CDC:0284:1 (VA) excreted cysts from 6-20 dpi and 6-22 dpi, respectively. One of five jirds inoculated with EGY excreted cysts on 8 dpi only. At necropsy, trophozoites were recovered from only three UNO-infected jirds but from all WB- and VA-infected jirds that excreted cysts. The one jird which excreted cysts of EGY was negative at necropsy, but EGY trophozoites were found in one non-patent jird. Isoelectric focusing indicated that these four strains of G. lamblia represented three zymodemes. WB and VA were assigned to one zymodeme, EGY to a second, and UNO, which shared common bands with both other zymodemes, to the third. Although the similarities and differences in infectivity and cyst excretion patterns appear to coincide with the zymodemes to which the strains can be assigned, further study is needed to examine the parasitologic behavior of these strains in relation to isoenzyme patterns. C1 CTR DIS CONTROL,DIV PARASIT DIS,PARASIT DIS BRANCH,MS F-13,ATLANTA,GA 30333. SUEZ CANAL UNIV,FAC MED,DEPT PARASITOL,ISMAILIA,EGYPT. NR 20 TC 10 Z9 10 U1 0 U2 1 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD JAN PY 1991 VL 44 IS 1 BP 63 EP 68 PG 6 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA EY659 UT WOS:A1991EY65900009 PM 1996742 ER PT J AU COLLINS, FH PASKEWITZ, SM CREWSOYEN, AE AF COLLINS, FH PASKEWITZ, SM CREWSOYEN, AE TI A GENETIC-STUDY OF PLASMODIUM SUSCEPTIBILITY IN THE AFRICAN MALARIA VECTOR ANOPHELES-GAMBIAE SO ANNALES DE LA SOCIETE BELGE DE MEDECINE TROPICALE LA English DT Article ID REFRACTORY STRAIN; ASSOCIATION; RESISTANCE; CYNOMOLGI; MIDGUT; LOCUS AB We are studying the interaction between malarial parasites and their mosquito hosts by a process based on the genetic selection of lines of the mosquito vector that will not support normal parasite development. The model system we are using is the mosquito Anopheles gambiae and a number of different human and non-human primate malarial parasites. Our first effort in this general approach involved the selection of a strain of An. gambiae that was able to encapsulate the malarial parasite during or just after its penetration of the mosquito midgut. This mosquito has been found to be highly refractory to a wide variety of different Plasmodium species and at least partially refractory to all four human malarial parasites. The basis of this phenomenon appears to be the mosquito's enhanced ability to mount a normal encapsulation response against invading pathogens or parasites. The late ookinete is enclosed in a heavily melanized capsule approximately 16-24 hours after the mosquito takes an infective blood meal. Encapsulation appears to be primarily humoral; electron microscopy reveals evidence of the phenomenon as the ookinete passes through or between midgut cells, and no hemocyte involvement has been observed. Subcellular structures in newly encapsulated parasites appear normal, indicating that live rather than dead or dying parasites are encapsulated. Preliminary studies suggest that two unlinked loci contribute to the refractory mosquito phenotype. One of these loci is very closely linked to a region of the mosquito genome that includes two esterases. These three loci, the esterase-associated refractoriness locus and the two esterase loci, are genetically inseparable not only in the refractory mosquito line but also in the unselected parental mosquito colony, suggesting that the esterase-associated refractoriness locus may either be an esterase or may be associated with the esterase loci in a chromosomal inversion. We have cloned one esterase gene that is contained within an inversion and are now commencing genetic studies to determine if this gene is the refractoriness-associated esterase. C1 UNIV WISCONSIN,DEPT ENTOMOL,MADISON,WI 53706. RP COLLINS, FH (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,MALARIA BRANCH,ATLANTA,GA 30333, USA. NR 8 TC 8 Z9 8 U1 0 U2 0 PU N V CEUTERICK PI LOUVAIN PA BRUSSELSESTRAAT 153, B-3000 LOUVAIN, BELGIUM SN 0365-6527 J9 ANN SOC BELG MED TR JI Ann. Soc. Belg. Med. Trop. PY 1991 VL 71 SU 1 BP 225 EP 232 PG 8 WC Tropical Medicine SC Tropical Medicine GA HF082 UT WOS:A1991HF08200021 PM 1793273 ER PT J AU SCHWARTZ, JS LEWIS, CE CLANCY, C KINOSIAN, MS RADANY, MH KOPLAN, JP AF SCHWARTZ, JS LEWIS, CE CLANCY, C KINOSIAN, MS RADANY, MH KOPLAN, JP TI INTERNISTS PRACTICES IN HEALTH PROMOTION AND DISEASE PREVENTION - A SURVEY SO ANNALS OF INTERNAL MEDICINE LA English DT Review ID ADULT CANCER PREVENTION; IMPROVING PHYSICIAN COMPLIANCE; PRIMARY CARE PHYSICIANS; FAMILY PHYSICIANS; SCREENING MAMMOGRAPHY; MEDICINE GUIDELINES; BREAST-CANCER; PERFORMANCE; SMOKING; ATTITUDES AB Objective: To estimate internists' use of disease prevention and health promotion activities, and to explore demographic, professional, behavioral, psychological, cognitive, and organizational factors associated with the use of such practices. Design: Mail survey. Setting and Subjects: A sample of 2610 members and fellows of the American College of Physicians (ACP) participated in the study. They engaged in patient care activities more than 20 hours per week and were stratified by gender and region. They lived in four geographic areas of the United States (Northeast, Southeast, Central, and West), comprising 21 ACP regions. Measurements: A questionnaire requesting background information as well as information about personal health; record keeping; use of immunizations (pneumococcal, influenza, tetanus, hepatitis B); use of screening tests and procedures for detecting cancer (breast examination, Papanicolaou smear, stool occult blood test) and other diseases (electrocardiograms, cholesterol level tests, chest radiographs); and behavioral counseling to promote health (in the areas of smoking, exercise, and alcohol and seat belt use). Main results: Internists used effective preventive interventions less frequently and ineffective practices more frequently than experts recommend. Internists' use of health promotion and disease prevention activities is associated with habit, attitude, and a lack of adequate knowledge. Younger physician age, general internal medicine practice, and personal health promotion and disease prevention practices were strongly associated with more appropriate use of recommended practices (P < 0.01). Conclusions: Internists' use of disease prevention and health promotion activities falls short of expert recommendations. Programs to improve the delivery of preventive services might be aimed at improving physicians' personal health practices, might be directed toward patients, and might include the development of effective systems to remind physicians. C1 CTR DIS CONTROL,ATLANTA,GA 30333. UNIV PENN,PHILADELPHIA,PA 19104. UNIV CALIF LOS ANGELES,SCH MED,DEPT MED,LOS ANGELES,CA 90024. VIRGINIA COMMONWEALTH UNIV,MED COLL VIRGINIA,RICHMOND,VA 23298. AMER COLL PHYSICIANS,PHILADELPHIA,PA. NR 75 TC 165 Z9 166 U1 1 U2 3 PU AMER COLL PHYSICIANS PI PHILADELPHIA PA INDEPENDENCE MALL WEST 6TH AND RACE ST, PHILADELPHIA, PA 19106-1572 SN 0003-4819 J9 ANN INTERN MED JI Ann. Intern. Med. PD JAN 1 PY 1991 VL 114 IS 1 BP 46 EP 53 PG 8 WC Medicine, General & Internal SC General & Internal Medicine GA EQ040 UT WOS:A1991EQ04000008 PM 1983932 ER PT J AU KELLERMANN, AL LEE, RK MERCY, JA AF KELLERMANN, AL LEE, RK MERCY, JA TI THE EPIDEMIOLOGIC BASIS FOR THE PREVENTION OF FIREARM INJURIES SO ANNUAL REVIEW OF PUBLIC HEALTH LA English DT Article DE SUICIDE; HOMICIDE; INJURY PREVENTION; ACCIDENTAL DEATH ID CIVILIAN GUNSHOT WOUNDS; CONCEPTUAL SHIFTS; HOMICIDE VICTIMS; NORTH-CAROLINA; CHILDREN; DEATH; REGULATIONS; FATALITIES; BALLISTICS; CALIFORNIA C1 UNIV TEXAS,MED BRANCH,SCH NURSING,GALVESTON,TX 77550. CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333. US DEPT HHS,PUBL HLTH SERV,CTR DIS CONTROL,ATLANTA,GA 30333. CTR DIS CONTROL,CTR INJURY CONTROL,ATLANTA,GA 30333. UNIV TENNESSEE,DEPT MED,DIV EMERGENCY MED,MEMPHIS,TN 38103. RP KELLERMANN, AL (reprint author), UNIV TENNESSEE,DEPT MED,DIV EMERGENCY MED,MEMPHIS,TN 38103, USA. RI Stockwell, Tim/B-6662-2012 NR 84 TC 61 Z9 61 U1 2 U2 4 PU ANNUAL REVIEWS INC PI PALO ALTO PA 4139 EL CAMINO WAY, PO BOX 10139, PALO ALTO, CA 94303-0139 SN 0163-7525 J9 ANNU REV PUBL HEALTH JI Annu. Rev. Public Health PY 1991 VL 12 BP 17 EP 40 PG 24 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA FL282 UT WOS:A1991FL28200002 PM 2049134 ER PT J AU ORSKOV, I WACHSMUTH, IK TAYLOR, DN ECHEVERRIA, P ROWE, B SAKAZAKI, R ORSKOV, F AF ORSKOV, I WACHSMUTH, IK TAYLOR, DN ECHEVERRIA, P ROWE, B SAKAZAKI, R ORSKOV, F TI 2 NEW ESCHERICHIA-COLI O-GROUPS - O172 FROM SHIGA-LIKE TOXIN II-PRODUCING STRAINS (EHEC) AND O173 FROM ENTEROINVASIVE ESCHERICHIA-COLI (EIEC) SO APMIS LA English DT Article DE ESCHERICHIA-COLI; SHIGA-LIKE TOXIN-II; NEW ESCHERICHIA-COLI O-GROUPS; ENTEROINVASIVE ESCHERICHIA-COLI; ANTIGEN CROSS REACTIONS AB Two Escherichia coli strains were established as antigenic test strains for two new O groups, O172 and O173. The O172 strain (EHEC) which produces >> Shiga-like << toxin II (verocytotoxin 2) was isolated from a case of haemorrhagic colitis while the enteroinvasive O173 strain (EIEC) originated from a child with diarrhoea. C1 ARMED FORCES RES INST MED SCI,BANGKOK,THAILAND. NATL INST HLTH,ENTEROBACTERIOL LABS,TOKYO 141,JAPAN. CENT PUBL HLTH LAB,DIV ENTER PATHOGENS,LONDON NW9 5HT,ENGLAND. CTR DIS CONTROL,ATLANTA,GA 30333. WALTER REED ARMY MED CTR,WASHINGTON,DC 20307. RP ORSKOV, I (reprint author), STATENS SERUM INST,WHO,COLLABORAT CTR REFERENCE & RES ESCHERICHIA,ARTILLERIVEJ 5,DK-2300 COPENHAGEN,DENMARK. NR 6 TC 18 Z9 19 U1 0 U2 0 PU MUNKSGAARD INT PUBL LTD PI COPENHAGEN PA 35 NORRE SOGADE, PO BOX 2148, DK-1016 COPENHAGEN, DENMARK SN 0903-4641 J9 APMIS JI APMIS PD JAN PY 1991 VL 99 IS 1 BP 30 EP 32 PG 3 WC Immunology; Microbiology; Pathology SC Immunology; Microbiology; Pathology GA EY365 UT WOS:A1991EY36500005 PM 1704241 ER PT J AU KIM, CM GRAVES, LM SWAMINATHAN, B MAYER, LW WEAVER, RE AF KIM, CM GRAVES, LM SWAMINATHAN, B MAYER, LW WEAVER, RE TI EVALUATION OF HYBRIDIZATION CHARACTERISTICS OF A CLONED PRF106 PROBE FOR LISTERIA-MONOCYTOGENES DETECTION AND DEVELOPMENT OF A NONISOTOPIC COLONY HYBRIDIZATION ASSAY SO APPLIED AND ENVIRONMENTAL MICROBIOLOGY LA English DT Article ID IDENTIFYING LISTERIA; EPIDEMIC LISTERIOSIS; DNA; CELLS; GENE; INFECTION; CLONING; FOODS AB An internal fragment (pRF106 fragment, ca. 500 bp) of a gene (msp) coding for a 60-kDa protein of Listeria monocytogenes serotype 1/2a was used to develop a screening method to discriminate between L. monocytogenes and avirulent Listeria spp. on primary isolation plates. The L. monocytogenes-derived probe fragment of pRF106 hybridized to a 13-kb fragment of L. monocytogenes and a 3-kb fragment of one cheese isolate strain of Listeria seeligeri under stringent hybridization conditions (mean thermal denaturation temperature [T(m)] - 5-degrees-C). The probe also hybridized to a 6-kb fragment of Listeria innocua, Listeria ivanovii, and L. seeligeri under less stringent hybridization conditions (T(m) - 17-degrees-C). The pRF106 fragment was labeled with digoxigenin-11-dUTP and used to develop a colony hybridization assay. Colonies from lithium chloride-phenylethanol-moxalactam agar were blotted onto nylon membranes. The cells were pretreated with microwaves before lysis with sodium hydroxide. DNA-DNA hybridization and posthybridization washing were done at high stringency (T(m) - 7-degrees-C). The nonisotopic colony hybridization procedure was specific for L. monocytogenes when evaluated against pure cultures of L. monocytogenes and other Listeria species, excluding the cheese isolate of L. seeligeri. Also, it was specific for L. monocytogenes when evaluated with Listeria-negative food enrichment cultures that were inoculated in the laboratory with Listeria species. C1 CTR DIS CONTROL,DIV SOCIOL,MENINGITIS & SPECIAL PATHOGENS BRANCH,ATLANTA,GA 30333. CTR DIS CONTROL,DIV VECTOR BORNE INFECT DIS,FT COLLINS,CO 80522. NR 35 TC 21 Z9 21 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0099-2240 J9 APPL ENVIRON MICROB JI Appl. Environ. Microbiol. PD JAN PY 1991 VL 57 IS 1 BP 289 EP 294 PG 6 WC Biotechnology & Applied Microbiology; Microbiology SC Biotechnology & Applied Microbiology; Microbiology GA ER206 UT WOS:A1991ER20600045 PM 1903627 ER PT J AU MORGAN, WM BLUMENSTEIN, BA AF MORGAN, WM BLUMENSTEIN, BA TI EXACT CONDITIONAL TESTS FOR HIERARCHICAL-MODELS IN MULTIDIMENSIONAL CONTINGENCY-TABLES SO APPLIED STATISTICS-JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C LA English DT Article DE CONDITIONAL TESTS; EXACT TESTS; HIERARCHICAL MODELS; MULTIDIMENSIONAL CONTINGENCY TABLES ID CELL COUNTS; ALGORITHM AB Exact conditional inference is routinely used for contingency tables with restricted dimensions such as 2 x 2, I x J and 2 x 2 x K tables. This paper introduces an algorithm and computer subroutine for the exact conditional test of hierarchical models in multidimensional contingency tables. The algorithm depends on complete enumeration, and the feasibility of using this algorithm is illustrated. Exact conditional inference is useful for sparse multidimensional tables or multidimensional tables with small sample size. C1 FRED HUTCHINSON CANC RES CTR,SEATTLE,WA 98104. RP MORGAN, WM (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 22 TC 7 Z9 7 U1 0 U2 0 PU BLACKWELL PUBL LTD PI OXFORD PA 108 COWLEY RD, OXFORD, OXON, ENGLAND OX4 1JF SN 0035-9254 J9 APPL STAT-J ROY ST C JI Appl. Stat.-J. R. Stat. Soc. PY 1991 VL 40 IS 3 BP 435 EP 442 DI 10.2307/2347523 PG 8 WC Statistics & Probability SC Mathematics GA FR623 UT WOS:A1991FR62300006 ER PT J AU ANZIL, AP RAO, C WRZOLEK, MA VISVESVARA, GS SHER, JH KOZLOWSKI, PB AF ANZIL, AP RAO, C WRZOLEK, MA VISVESVARA, GS SHER, JH KOZLOWSKI, PB TI AMEBIC MENINGOENCEPHALITIS IN A PATIENT WITH AIDS CAUSED BY A NEWLY RECOGNIZED OPPORTUNISTIC PATHOGEN - LEPTOMYXID AMEBA SO ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE LA English DT Article ID ACQUIRED IMMUNODEFICIENCY SYNDROME; ACANTHAMOEBA MENINGOENCEPHALITIS; ENCEPHALITIS; INFECTION AB A fatal case of meningoencephalitis due to a leptomyxid ameba in a patient with the acquired immunodeficiency syndrome is presented. This opportunistic organism has not been previously recognized as a human pathogen. A 36-year-old male intravenous drug abuser died after an 18-day hospital course heralded by fever and headache and followed by nuchal rigidity and hemiparesis. Computed tomography of the head showed multiple hypodense lesions. Neuropathologic examination showed that in addition to human immunodeficiency virus encephalomyelitis, there was multifocal meningoencephalitis with trophozoites and cysts morphologically indistinguishable from those of Acanthamoeba. These organisms were also found in the kidneys and adrenal glands. By immunofluorescence, the parasites showed antigenic identity with a free-living leptomyxid ameba and failed to react with any of a spectrum of antiacanthamoeba antisera. This emphasizes the importance of immunofluorescence identification of morphologically indistinguishable ameba species. C1 KINGS CTY HOSP CTR,DEPT PATHOL,BROOKLYN,NY 11203. NEW YORK STATE INST BASIC RES DEV DISABILITIES,STATEN ISL,NY 10314. CTR DIS CONTROL,CTR INFECT DIS,ATLANTA,GA 30333. RP ANZIL, AP (reprint author), SUNY HLTH SCI CTR,450 CLARKSON AVE,BOX 25,BROOKLYN,NY 11203, USA. NR 13 TC 76 Z9 77 U1 0 U2 2 PU COLLEGE AMER PATHOLOGISTS PI NORTHFIELD PA C/O KIMBERLY GACKI, 325 WAUKEGAN RD, NORTHFIELD, IL 60093-2750 SN 0003-9985 J9 ARCH PATHOL LAB MED JI Arch. Pathol. Lab. Med. PD JAN PY 1991 VL 115 IS 1 BP 21 EP 25 PG 5 WC Medical Laboratory Technology; Medicine, Research & Experimental; Pathology SC Medical Laboratory Technology; Research & Experimental Medicine; Pathology GA EU517 UT WOS:A1991EU51700007 PM 1987909 ER PT J AU LAIRMORE, MD POST, AA GOLDSMITH, CS FOLKS, TM AF LAIRMORE, MD POST, AA GOLDSMITH, CS FOLKS, TM TI CYTOKINE ENHANCEMENT OF SIMIAN IMMUNODEFICIENCY VIRUS (SIV/MAC) FROM A CHRONICALLY INFECTED CLONED T-CELL LINE (HUT-78) SO ARCHIVES OF VIROLOGY LA English DT Article ID TUMOR-NECROSIS-FACTOR; FACTOR-ALPHA; MONONUCLEAR-CELLS; HIV REPLICATION; EXPRESSION; INVITRO; INTERLEUKIN-1 AB Simian immunodeficiency viruses (SIV) are a family of primate lentiviruses similar to human immunodeficiency viruses (HIV) in their genetic sequence and pathogenesis. However, host-derived cofactors which may determine the extent of viral replication are not clearly defined for SIV or HIV infections. A HuT-78 cell line chronically infected with SIV/mac strain 251, was biologically cloned and characterized for the ability to produce infectious viral particles, viral structural protein profile, cellular antigen surface phenotype and tested to determine the effects of recombinant cytokines on SIV replication. Reverse transcriptase (RT) assay was used to measure the replication of SIV/mac in response to various concentrations of recombinant cytokines (1-1000 units/ml). We report that tumor necrosis factor-alpha (rTNF-alpha), gamma-interferon (rIFN-gamma), interleukin 2 (rIL-2), and granulocyte-macrophage colony stimulating factor (rGM-CSF) induced approximately a 2 to 3 fold increase in virus RT activity compared with untreated SIV-infected HuT-78 cells. In contrast, viral replication was not enhanced or minimally enhanced by interleukin 1 (rIL-1), interleukin 3 (rIL-3), or interleukin 4 (rIL-4) at similar dosages. Furthermore, SIV replication in response to rTNF-alpha and rIFN-gamma occurred in a dose dependent fashion. These data suggest that SIV-infected T-lymphocyte lines are responsive to particular cytokines resulting in increased virus production. C1 CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,RETROVIRUSES DIS BRANCH,ATLANTA,GA 30333. RP LAIRMORE, MD (reprint author), OHIO STATE UNIV,DEPT VET PATHOBIOL,1925 COFFEY RD,COLUMBUS,OH 43210, USA. NR 21 TC 10 Z9 10 U1 0 U2 0 PU SPRINGER-VERLAG WIEN PI VIENNA PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 VIENNA, AUSTRIA SN 0304-8608 J9 ARCH VIROL JI Arch. Virol. PY 1991 VL 121 IS 1-4 BP 43 EP 53 DI 10.1007/BF01316743 PG 11 WC Virology SC Virology GA GV442 UT WOS:A1991GV44200005 PM 1722091 ER PT J AU HIERHOLZER, JC STONE, YO BRODERSON, JR AF HIERHOLZER, JC STONE, YO BRODERSON, JR TI ANTIGENIC RELATIONSHIPS AMONG THE 47 HUMAN ADENOVIRUSES DETERMINED IN REFERENCE HORSE ANTISERA SO ARCHIVES OF VIROLOGY LA English DT Article ID RENAL-TRANSPLANT RECIPIENT; RESTRICTION ENZYME ANALYSIS; DOT-BLOT HYBRIDIZATION; SUBGENUS-D; ENTERIC ADENOVIRUSES; EPIDEMIC KERATOCONJUNCTIVITIS; BIOCHEMICAL-CHARACTERIZATION; IMMUNOCOMPROMISED HOSTS; MOLECULAR EPIDEMIOLOGY; ACUTE GASTROENTERITIS AB Reference equine antisera to all 47 serotypes of human adenoviruses presently described have been prepared and evaluated by reciprocal neutralization and hemagglutination-inhibition tests. All tests were carried to endpoint dilutions a minimum of five times in each direction to give accurate values for homologous and heterologous antibody titers. Significant cross-reactions in the horse antisera were compared to similar data obtained from rabbit antisera. Using this analysis, major antigenic relationships exist among types 12-18-31 of subgenus A, types 7-11-14 and 34-35 of subgenus B, types 8-9-10, 10-19-37, 13-38-39, 15-22-42, 20-47, 24-32-33-46, and 29-45 of subgenus D, types 16-4 between subgenera B and E, and types 40-41 of subgenus F. Across all subgenera, types 8, 10, 13, 15, 17, 19, 26, 29, 39, 40, and 43 have antigenic moieties found most frequently in other types, averaging 12 heterologous reactions per type when summing both tests in both directions. Types 20, 30, 32, and 45 exhibit shared determinants slightly less often, with a mean of 8 heterologous reactions per type. C1 CTR DIS CONTROL,CID SCI RESOURCES PROGRAM,ATLANTA,GA 30333. RP HIERHOLZER, JC (reprint author), CTR DIS CONTROL,CID,DIV VIRAL DIS,RESP & ENTER VIRUSES BRANCH,G 17,ATLANTA,GA 30333, USA. NR 68 TC 79 Z9 80 U1 0 U2 0 PU SPRINGER-VERLAG WIEN PI VIENNA PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 VIENNA, AUSTRIA SN 0304-8608 J9 ARCH VIROL JI Arch. Virol. PY 1991 VL 121 IS 1-4 BP 179 EP 197 DI 10.1007/BF01316753 PG 19 WC Virology SC Virology GA GV442 UT WOS:A1991GV44200015 PM 1759904 ER PT J AU RUO, SL SANCHEZ, A ELLIOTT, LH BRAMMER, LS MCCORMICK, JB FISHERHOCH, SP AF RUO, SL SANCHEZ, A ELLIOTT, LH BRAMMER, LS MCCORMICK, JB FISHERHOCH, SP TI MONOCLONAL-ANTIBODIES TO 3 STRAINS OF HANTAVIRUSES - HANTAAN, R22, AND PUUMALA SO ARCHIVES OF VIROLOGY LA English DT Article ID RENAL SYNDROME HFRS; KOREAN HEMORRHAGIC-FEVER; SYNDROME VIRUSES; CODING STRATEGY; GENOME SEGMENT; AGENT; IMMUNOPRECIPITATION; IDENTIFICATION; SEROTYPES; CULTURE AB Thirty hybrid cell lines that produce monoclonal antibodies to three strains of hantaviruses have been generated and characterized. One clone specific to Hantaan 76-118 strain, four clones specific to Rattus strains and one clone specific to Puumala virus have been identified. Most of the monoclones produced antibodies specific to nucleoproteins. Only two monoclones were found to produce glycoprotein specific, neutralizing antibodies. The immunofluorescent (IFA) staining patterns of the monoclonal antibodies show consistent correlation with viral protein specificities as described for other hemorrhagic fever viruses. Cross-reactivity studies with hantaviruses tested demonstrate conserved antigenic sites on nucleoproteins among these hantaviruses tested. Puumala specific monoclones, produced for the first time, reveal both conserved and strain specific sites on the viral nucleoproteins of the Scandinavian virus. RP RUO, SL (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,SPECIAL PATHOGENS BRANCH,BLDG 15,ATLANTA,GA 30333, USA. NR 24 TC 61 Z9 65 U1 0 U2 0 PU SPRINGER-VERLAG WIEN PI VIENNA PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 VIENNA, AUSTRIA SN 0304-8608 J9 ARCH VIROL JI Arch. Virol. PY 1991 VL 119 IS 1-2 BP 1 EP 11 DI 10.1007/BF01314318 PG 11 WC Virology SC Virology GA GA147 UT WOS:A1991GA14700001 PM 1907448 ER PT J AU MCKOLANIS, JR RAGAB, AH SCHMID, DS AF MCKOLANIS, JR RAGAB, AH SCHMID, DS TI INVITRO ENHANCEMENT OF NATURAL-KILLER-CELL ACTIVITY AGAINST HERPESVIRUS-INFECTED TARGETS IN PATIENTS WITH ACUTE LYMPHOCYTIC-LEUKEMIA SO ARCHIVES OF VIROLOGY LA English DT Article ID ACUTE LYMPHOBLASTIC-LEUKEMIA; HUMAN-LEUKOCYTE INTERFERON; SIMPLEX VIRUS TYPE-1; NK CELLS; MARROW TRANSPLANTATION; VARICELLA; CHILDREN; ZOSTER; INTERLEUKIN-2; ACYCLOVIR AB The present study was carried out to determine whether natural killer (NK) activity against virus-infected target cells could be enhanced in peripheral blood lymphocytes (PBL) taken from patients with acute lymphocytic leukemia. Nonspecific cell-mediated killing of heterologous herpesvirus-infected B lymphoblastoid targets could be enhanced by pretreating PBL with interferons-alpha or -gamma, or with interleukin-2. NK activity was substantially enhanced over that of untreated cells, and virtually all cytolytic activity was attributable to CD16+ NK cells. Pretreatment of PBL with a combination of cytokines resulted in additive, but never synergistic enhancement of NK activity. The results suggest that cytokine therapy may provide a useful means for treating severe varicella zoster infections in immunocompromised children. C1 EMORY UNIV,DEPT PEDIAT HAEMATOL ONCOL,ATLANTA,GA 30322. CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,ATLANTA,GA 30333. EMORY UNIV,DEPT PATHOL,ATLANTA,GA 30322. NR 36 TC 0 Z9 0 U1 0 U2 0 PU SPRINGER-VERLAG WIEN PI VIENNA PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 VIENNA, AUSTRIA SN 0304-8608 J9 ARCH VIROL JI Arch. Virol. PY 1991 VL 117 IS 1-2 BP 17 EP 28 DI 10.1007/BF01310489 PG 12 WC Virology SC Virology GA FD146 UT WOS:A1991FD14600002 PM 1848749 ER PT J AU SANCHEZFAUQUIER, A GUILLEN, M MARTIN, J KENDAL, AP MELERO, JA AF SANCHEZFAUQUIER, A GUILLEN, M MARTIN, J KENDAL, AP MELERO, JA TI CONSERVATION OF EPITOPES RECOGNIZED BY MONOCLONAL-ANTIBODIES AGAINST THE SEPARATED SUBUNITS OF INFLUENZA HEMAGGLUTININ AMONG TYPE-A VIRUSES OF THE SAME AND DIFFERENT SUBTYPES SO ARCHIVES OF VIROLOGY LA English DT Article ID ANTIGENIC STRUCTURE; HA2; DRIFT; SITES AB Monoclonal antibodies raised against the separated hemagglutinin subunits (HA1 and HA2) of influenza A/Vic/3/75 (H3N2) virus were tested against a large panel of human and avian strains. The epitopes recognized by most antibodies were conserved among subtype H3 viruses, but reactivity of some antibodies with members of other subtypes was also observed. Particularly, the H4 virus reacted with most antibodies directed against the HA2 subunit. These results are discussed in terms of sequence similarities between subtypes and application of these antibodies as subtyping reagents. C1 CTR NACL MICROBIOL VIROL & INMUNOL SANITARIAS MAJADAHONDA,DEPT MOLEC BIOL,E-28220 MADRID,SPAIN. CTR DIS CONTROL,DIV VIRAL DIS,INFLUENZA BRANCH,ATLANTA,GA 30333. NR 18 TC 7 Z9 7 U1 0 U2 2 PU SPRINGER-VERLAG WIEN PI VIENNA PA SACHSENPLATZ 4-6, PO BOX 89, A-1201 VIENNA, AUSTRIA SN 0304-8608 J9 ARCH VIROL JI Arch. Virol. PY 1991 VL 116 IS 1-4 BP 285 EP 293 DI 10.1007/BF01319250 PG 9 WC Virology SC Virology GA EZ173 UT WOS:A1991EZ17300024 PM 1705790 ER PT J AU LEFAOU, AE MORSE, SA AF LEFAOU, AE MORSE, SA TI CHARACTERIZATION OF A SOLUBLE FERRIC REDUCTASE FROM NEISSERIA-GONORRHOEAE SO BIOLOGY OF METALS LA English DT Article DE NEISSERIA GONORRHOEAE; GONOCOCCI; FERRIC REDUCTASE ID IRON; PROTEIN; LACTOFERRIN; TRANSFERRIN; TRANSPORT; CLONING AB An NADH-dependent ferric reductase was identified in extracts of Neisseria gonorrhoeae. Enzyme activity was measured in an assay using ferrozine as the ferrous iron acceptor. Ferric reductase activity was enhanced by Mg2+ and flavine nucleotides. The enzyme reduced both citrate- and diphosphate-bound ferric iron as well as ferric hydroxide (Imferon). However, no activity was observed with either 30%-iron-saturated transferrin or with the gonococcal iron-binding protein, Fbp. The ferric reductase was found primarily within the cytoplasmic cell fraction. The soluble ferric reductase was purified 110-fold by ammonium sulfate precipitation, gel and anion-exchange chromatography. Results obtained following gel chromatography and SDS/polyacrylamide gel electrophoresis suggested that the enzyme had a molecular mass of about 25 kDa. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV SEXUALLY TRANSMITTED DIS LAB RES,ATLANTA,GA 30333. NR 31 TC 18 Z9 18 U1 0 U2 0 PU SPRINGER VERLAG PI NEW YORK PA 175 FIFTH AVE, NEW YORK, NY 10010 SN 0933-5854 J9 BIOL MET PY 1991 VL 4 IS 2 BP 126 EP 131 PG 6 WC Biochemistry & Molecular Biology; Biology SC Biochemistry & Molecular Biology; Life Sciences & Biomedicine - Other Topics GA FK554 UT WOS:A1991FK55400009 PM 1908693 ER PT J AU CUTTS, FT HENDERSON, RH CLEMENTS, CJ CHEN, RT PATRIARCA, PA AF CUTTS, FT HENDERSON, RH CLEMENTS, CJ CHEN, RT PATRIARCA, PA TI PRINCIPLES OF MEASLES CONTROL SO BULLETIN OF THE WORLD HEALTH ORGANIZATION LA English DT Article ID VACCINATION; AFRICA AB WHO's Expanded Programme on Immunization has significantly helped to reduce global morbidity and mortality from measles. Recently, some African countries with high vaccine coverage levels have reported measles outbreaks in children above the current target age group for immunization. Outbreaks such as these are to be expected, unless close to 100% of the population are immunized with a vaccine which is 100% effective. Success of an immunization programme requires identification of the distribution and ages of susceptible children and reduction of their concentration throughout the community. Priority should be given to urban and densely populated rural areas. In large urban areas, high coverage of infants must be achieved soon after the age at which they lose their maternal antibodies and become susceptible. This will be facilitated by the introduction of high-dose measles vaccines which can be given at 6 months of age. Where measles incidence is increasing among children aged over 2 years, immunization of older children may be considered during contacts with the health care system, or at primary school entry, if this does not divert resources from immunization of younger children. Health workers should be informed of the predicted changes in measles epidemiology following immunization. The collection, analysis and use of data on measles (vaccine coverage, morbidity and mortality) should be improved at all levels of the health care system in order to monitor the immunization programme's overall impact, identify pockets of low coverage, and allow early detection of and response to measles outbreaks. C1 WHO,CH-1211 GENEVA 27,SWITZERLAND. EXPANDED PROGRAMME IMMUNIZAT,GENEVA,SWITZERLAND. RP CUTTS, FT (reprint author), CTR DIS CONTROL,DIV IMMUNIZAT,EPIDEMIOL RES STN,EO5,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 18 TC 57 Z9 61 U1 0 U2 2 PU WORLD HEALTH ORGANIZATION PI GENEVA 27 PA DISTRIBUTION AND SALES, CH-1211 GENEVA 27, SWITZERLAND SN 0042-9686 J9 B WORLD HEALTH ORGAN JI Bull. World Health Organ. PY 1991 VL 69 IS 1 BP 1 EP 7 PG 7 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA FL531 UT WOS:A1991FL53100001 PM 2054914 ER PT J AU CUTTS, FT AF CUTTS, FT TI STRATEGIES TO IMPROVE IMMUNIZATION SERVICES IN URBAN AFRICA SO BULLETIN OF THE WORLD HEALTH ORGANIZATION LA English DT Article ID PRIMARY HEALTH-CARE; MEASLES; MOZAMBIQUE; COMMUNITY; MORTALITY; COVERAGE; REASONS; PROGRAM AB The urban poor constitute a rapidly increasing proportion of the population in developing countries. Focusing attention on underserved urban slums and squatter settlements will contribute greatly to immunization programme goals, because these areas account for 30-50% of urban populations, usually provide low access to health services, carry a large burden of disease mortality, and act as sources of infection for the city and surrounding rural areas. Improvement of urban immunization programmes requires intersectoral collaboration, use of all opportunities to vaccinate eligible children and mothers, identification of low-coverage neighbourhoods and execution of extra activities in these neighbourhoods, and community mobilization to identify and refer persons for vaccination. Improved disease surveillance helps to identify high-risk populations and document programme impact. New developments in vaccines, such as the high-dose Edmonston-Zagreb vaccine, will allow changes in the immunization schedule that facilitate the control of specific diseases. Finally, operational research can assist managers to conduct urban situation assessments, evaluate programme performance at the "micro" level, and design and monitor interventions. RP CUTTS, FT (reprint author), CTR DIS CONTROL,DIV IMMUNIZAT,E05,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 29 TC 17 Z9 17 U1 0 U2 2 PU WORLD HEALTH ORGANIZATION PI GENEVA 27 PA DISTRIBUTION AND SALES, CH-1211 GENEVA 27, SWITZERLAND SN 0042-9686 J9 B WORLD HEALTH ORGAN JI Bull. World Health Organ. PY 1991 VL 69 IS 4 BP 407 EP 414 PG 8 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA GJ303 UT WOS:A1991GJ30300005 PM 1934234 ER PT J AU HOPKINS, DR RUIZTIBEN, E AF HOPKINS, DR RUIZTIBEN, E TI STRATEGIES FOR DRACUNCULIASIS ERADICATION SO BULLETIN OF THE WORLD HEALTH ORGANIZATION LA English DT Article AB In 1991 the Forty-fourth World Health Assembly declared the goal of eradicating dracunculiasis (guinea worm disease) by the end of 1995. This article summarizes the recommended strategies for surveillance and interventions in national dracunculiasis eradication programmes. It is based on personal experience with dracunculiasis programmes in Ghana, Nigeria and Pakistan. Three phases are described: establishment of a national programme office and conduct of a baseline survey; implementation of interventions; and case containment. The relevance of dracunculiasis eradication activities to strengthening of primary health care in the three countries is discussed briefly. Similar strategies would help eradicate this disease in the remaining endemic countries. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS F22,GUINEA WORM TASK FORCE,ATLANTA,GA 30333. CARTER CTR INC,GLOBAL 2000,ATLANTA,GA. WHO,COLLABORATING CTR RES TRAINING & ERADICAT DRACUNCULIASIS,CH-1211 GENEVA 27,SWITZERLAND. NR 7 TC 41 Z9 42 U1 1 U2 8 PU WORLD HEALTH ORGANIZATION PI GENEVA 27 PA DISTRIBUTION AND SALES, CH-1211 GENEVA 27, SWITZERLAND SN 0042-9686 J9 B WORLD HEALTH ORGAN JI Bull. World Health Organ. PY 1991 VL 69 IS 5 BP 533 EP 540 PG 8 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA GR100 UT WOS:A1991GR10000003 PM 1835673 ER PT J AU TSAI, JF TSAI, JH CHANG, WY TON, TC AF TSAI, JF TSAI, JH CHANG, WY TON, TC TI ELEVATION OF CIRCULATING IMMUNE-COMPLEXES AND ITS RELATIONSHIP TO ALPHA-FETOPROTEIN LEVELS IN PATIENTS WITH HEPATITIS-B SURFACE ANTIGEN-POSITIVE HEPATOCELLULAR-CARCINOMA SO CANCER INVESTIGATION LA English DT Article ID SERUM AB In an attempt to evaluate the relationship between circulating immune complexes (CIC) and alpha-fetoprotein (AFP), CIC and AFP were detected in 93 hepatitis B surface antigen-positive (HBsAg+) patients with hepatocellular carcinoma (HCC) and 54 healthy controls. The median level of 3% PEG (polyethylene glycol)-CIC and C1q-CIC were higher in patients than in controls (p < 0.001). In patients with HCC, the prevalence of elevated 3% PEG-CIC, C1q-CIC, and AFT was 27.9%, 55.9%, and 77.4%, respectively. There was association between AFP and 3% PEG-CIC positivity (p < 0.01). The median level of 3% PEG-CIC and C1q-CIC increased as AFP levels elevated (p < 0.05), but decreased as AFP exceeded 1599 ng/ml (p < 0.05). For adjusting the effect of impaired liver function on the level of CIC, multivariate analysis with stepwise logistic regression revealed that 3% PEG-CIC was associated, in a dose-related fashion, with an increased risk for developing HCC (odds ratio = 1.003, p < 0.001). These results imply that elevation of 3% PEG-CIC may be related to tumor mass. Additionally, 3% PEG-CIC is a useful marker to monitor therapy with transcatheter arterial embolization in patients with HBsAg+ HCC. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL DIS,ATLANTA,GA 30333. RP TSAI, JF (reprint author), KAOSIUNG MED COLL,DEPT INTERNAL MED,100 SHIH CHUAN 1 RD,KAOHSIUNG 80708,TAIWAN. NR 21 TC 17 Z9 17 U1 0 U2 0 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0735-7907 J9 CANCER INVEST JI Cancer Invest. PY 1991 VL 9 IS 2 BP 137 EP 143 DI 10.3109/07357909109044224 PG 7 WC Oncology SC Oncology GA GA046 UT WOS:A1991GA04600004 PM 1713804 ER PT J AU PETERMAN, TA JAFFE, HW FRIEDMANKIEN, AE WEISS, RA AF PETERMAN, TA JAFFE, HW FRIEDMANKIEN, AE WEISS, RA TI THE ETIOLOGY OF KAPOSIS-SARCOMA SO CANCER SURVEYS LA English DT Article ID ACQUIRED-IMMUNODEFICIENCY-SYNDROME; LONG-TERM CULTURE; HOMOSEXUAL MEN; CYTOMEGALO-VIRUS; SYNDROME AIDS; SEROLOGICAL ASSOCIATION; ANTIBODY PATTERNS; INTERFERON-ALPHA; SAUDI-ARABIA; CELLS C1 ROYAL CANC HOSP,CHESTER BEATTY LABS,LONDON SW3 6JB,ENGLAND. NYU MED CTR,DEPT DERMATOL & MICROBIOL,NEW YORK,NY 10016. RP PETERMAN, TA (reprint author), CTR DIS CONTROL,MAILSTOP E02,ATLANTA,GA 30333, USA. NR 69 TC 32 Z9 32 U1 0 U2 0 PU COLD SPRING HARBOR LAB PRESS PI PLAINVIEW PA 1 BUNGTOWN RD, PLAINVIEW, NY 11724 SN 0261-2429 J9 CANCER SURV JI Cancer Surv. PY 1991 VL 10 BP 23 EP 37 PG 15 WC Oncology SC Oncology GA HP482 UT WOS:A1991HP48200003 PM 1821321 ER PT B AU MATTE, TD FIGUEROA, JP OSTROWSKI, S BURR, G JACKSONHUNT, L BAKER, EL AF MATTE, TD FIGUEROA, JP OSTROWSKI, S BURR, G JACKSONHUNT, L BAKER, EL BE BERRY, MR ELIAS, RW TI RELATIONSHIP BETWEEN SOIL LEAD LEVELS AND BLOOD LEAD LEVELS AMONG CHILDREN LIVING NEAR A LEAD SMELTER IN JAMAICA SO CHEMICAL SPECIATION AND BIOAVAILABILITY, VOL 3, NOS 3-4, DECEMBER 1991: PROCEEDINGS OF THE SYMPOSIUM ON THE BIOAVAILABILITY AND DIETARY EXPOSURE OF LEAD LA English DT Proceedings Paper CT SYMP ON THE BIOAVAILABILITY AND DIETARY EXPOSURE OF LEAD CY SEP 24-27, 1990 CL CHAPEL HILL, NC SP UN ENVIRONM PROGRAM, SOC ENVIRONM GEOCHEM & HLTH RP MATTE, TD (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SCIENCE AND TECHNOLOGY LETTERS PI NORTHWOOD PA NORTHWOOD BN 0-946682-10-0 PY 1991 BP 173 EP 177 PG 5 WC Environmental Sciences; Public, Environmental & Occupational Health; Toxicology SC Environmental Sciences & Ecology; Public, Environmental & Occupational Health; Toxicology GA BV64D UT WOS:A1991BV64D00022 ER PT J AU POSNER, JC AF POSNER, JC TI EVALUATION OF SORBENTS FOR THE COLLECTION AND ANALYSIS OF TRACE LEVELS OF AIRBORNE VAPORS - BIS(2-CHLOROETHYL)SULFIDE (MUSTARD), A CASE-STUDY SO CHEMOSPHERE LA English DT Article ID CARBON AB As part of the Department of Health and Human Services's (DHHS's) responsibility for the oversight of safety and health during the destruction of obsolete chemical warfare munitions and agent stockpiles by the Department of Defense (DOD), investigators from the National Institute for Occupational Safety and Health (NIOSH) have conducted research on air monitoring methods that the Department of Defense uses for measuring the workplace and environmental concentrations of chemical warfare agents. This paper concerns work on part of this research which was aimed at evaluating sorbents for the collection of the blister agent bis(2-chloroethyl)sulfide, known as mustard or HD, from air. Twenty-three sorbents were screened and compared to Tenax, the currently-used sorbent. A screening technique based on the assumption that the sorbents would behave like chromatographic columns was used to select those whose predicted retention volumes at ambient temperature were greater than or equal to that of Tenax. Two promising alternatives were found from the screening experiments. Further testing of those two sorbents, however, uncovered other problems with their use for the collection and recovery of HD which made them unsuitable. The screening technique was shown to be useful for comparison only and did not predict the capacities of sorbents accurately. RP POSNER, JC (reprint author), NIOSH,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 9 TC 2 Z9 2 U1 1 U2 1 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0045-6535 J9 CHEMOSPHERE JI Chemosphere PY 1991 VL 22 IS 5-6 BP 461 EP 472 DI 10.1016/0045-6535(91)90058-L PG 12 WC Environmental Sciences SC Environmental Sciences & Ecology GA FN424 UT WOS:A1991FN42400004 ER PT J AU JASON, JM AF JASON, JM TI ABUSE, NEGLECT, AND THE HIV-INFECTED CHILD SO CHILD ABUSE & NEGLECT LA English DT Article RP JASON, JM (reprint author), CTR DIS CONTROL,NATL AIDS INFORMAT & EDUC PROGRAM,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 2 TC 1 Z9 1 U1 0 U2 1 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0145-2134 J9 CHILD ABUSE NEGLECT JI Child Abuse Negl. PY 1991 VL 15 SU 1 BP 79 EP 88 DI 10.1016/0145-2134(91)90011-2 PG 10 WC Family Studies; Psychology, Social; Social Work SC Family Studies; Psychology; Social Work GA FB605 UT WOS:A1991FB60500010 PM 2032130 ER PT J AU HABER, M CHEN, CCH WILLIAMSON, GD AF HABER, M CHEN, CCH WILLIAMSON, GD TI ANALYSIS OF REPEATED CATEGORICAL RESPONSES FROM FULLY AND PARTIALLY CROSS-CLASSIFIED DATA SO COMMUNICATIONS IN STATISTICS-THEORY AND METHODS LA English DT Article DE CONTINGENCY TABLES; IGNORABLE NONRESPONSE; LINEAR MODELS; MARGINAL CONFORMITY; MAXIMUM LIKELIHOOD; REPEATED MEASUREMENTS ID MAXIMUM-LIKELIHOOD ESTIMATION; INCOMPLETE DATA; TESTING EQUALITY; MISSING DATA; PROPORTIONS AB Many follow-up studies involve categorical data measured on the same individual at different times. Frequently, some of the individuals are missing one or more of the measurements. This results in a contingency table with both fully and partially cross-classified data. Two models can be used to analyze data of this type: (i) The multiple-sample model, in which all the study subjects with the same configuration of missing observations are considered a separate sample. (ii) The single-sample model, which assumes that the missing observations are the result of a mechanism causing subjects to lose the information from one or some of the measurements. In this work we compare the two approaches and show that under certain conditions, the two models yield the same maximum likelihood estimates of the cell probabilities in the underlying contingency table. C1 EMORY UNIV,SCH PUBL HLTH,DIV BIOSTAT,ATLANTA,GA 30322. CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,ATLANTA,GA 30333. NR 20 TC 2 Z9 2 U1 0 U2 0 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0361-0926 J9 COMMUN STAT THEORY JI Commun. Stat.-Theory Methods PY 1991 VL 20 IS 10 BP 3293 EP 3313 DI 10.1080/03610929108830703 PG 21 WC Statistics & Probability SC Mathematics GA GK939 UT WOS:A1991GK93900017 ER PT B AU SCHRADER, SM BREITENSTEIN, M TURNER, TW SIMON, SD AF SCHRADER, SM BREITENSTEIN, M TURNER, TW SIMON, SD BE BACCETTI, B TI LONGITUDINAL-STUDY OF SEMEN QUALITY OF UNEXPOSED WORKERS - SEMINAL PLASMA CHARACTERISTICS SO COMPARATIVE SPERMATOLOGY 20 YEARS AFTER SE SERONO SYMPOSIA PUBLICATIONS FROM RAVEN PRESS LA English DT Proceedings Paper CT 6TH INTERNATIONAL CONGRESS OF SPERMATOLOGY CY AUG 30-SEP 05, 1990 CL SIENA, ITALY SP SERONO SYMPOSIA RP SCHRADER, SM (reprint author), NIOSH,DIV BIOMED & BEHAV SCI,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU RAVEN PRESS PI NEW YORK PA NEW YORK BN 0-88167-654-3 J9 SERONO SYM PY 1991 VL 75 BP 905 EP 908 PG 4 WC Andrology; Biology; Obstetrics & Gynecology SC Endocrinology & Metabolism; Life Sciences & Biomedicine - Other Topics; Obstetrics & Gynecology GA BV61B UT WOS:A1991BV61B00161 ER PT J AU ING, RT AF ING, RT TI MOLLY - A LANGUAGE FOR TYPESETTING MOLECULAR-STRUCTURE DIAGRAMS SO COMPUTERS & CHEMISTRY LA English DT Article ID SOFTWARE AB MOLLY is a language for drawing 2-D molecular structure diagrams commonly seen in scientific journals and textbooks. Implemented as a PIC macro library, MOLLY is integrated with the TROFF family of typesetting software available for UNIX and MS-DOS operating systems. The language is device-independent and can be used to produce publication-quality molecular drawings on laser printers and phototypesetters. MOLLY offers a new paradigm for drawing chemical structures - atomic groups are drawn in a way analogous to how a branching tree or road is traversed. The atomic groups and bonds are placed intuitively and accurately at any orientation - even when entire structures are rotated and reflected. The user can extend the language and build libraries of reusable moieties and templates. This paper describes the design of MOLLY and gives examples of its use. RP ING, RT (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333, USA. NR 12 TC 0 Z9 0 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0097-8485 J9 COMPUT CHEM JI Comput. Chem. PY 1991 VL 15 IS 3 BP 185 EP 201 DI 10.1016/0097-8485(91)80002-4 PG 17 WC Chemistry, Multidisciplinary; Computer Science, Interdisciplinary Applications SC Chemistry; Computer Science GA GA834 UT WOS:A1991GA83400002 ER PT J AU SHINNICK, TM AF SHINNICK, TM TI HEAT-SHOCK PROTEINS AS ANTIGENS OF BACTERIAL AND PARASITIC PATHOGENS SO CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY LA English DT Review ID MYCOBACTERIUM-BOVIS BCG; PLASMODIUM-FALCIPARUM; ESCHERICHIA-COLI; STRESS PROTEINS; SCHISTOSOMA-MANSONI; COMMON ANTIGEN; MAJOR IMMUNOGEN; T-CELLS; 65-KILODALTON ANTIGEN; MONOCLONAL-ANTIBODY RP SHINNICK, TM (reprint author), CTR DIS CONTROL,DIV BACTERIAL DIS,HANSEN DIS LAB,ATLANTA,GA 30333, USA. NR 102 TC 125 Z9 130 U1 0 U2 2 PU SPRINGER VERLAG PI NEW YORK PA 175 FIFTH AVE, NEW YORK, NY 10010 SN 0070-217X J9 CURR TOP MICROBIOL JI Curr. Top. Microbiol. Immunol. PY 1991 VL 167 BP 145 EP 160 PG 16 WC Immunology; Microbiology SC Immunology; Microbiology GA FA593 UT WOS:A1991FA59300009 PM 1675978 ER PT J AU VOGT, RF CROSS, GD PHILLIPS, DL HENDERSON, LO HANNON, WH AF VOGT, RF CROSS, GD PHILLIPS, DL HENDERSON, LO HANNON, WH TI INTERLABORATORY STUDY OF CELLULAR FLUORESCENCE INTENSITY MEASUREMENTS WITH FLUORESCEIN-LABELED MICROBEAD STANDARDS SO CYTOMETRY LA English DT Article DE FLOW CYTOMETRY; IMMUNOPHENOTYPING; CD4-LYMPHOCYTES; QUALITY CONTROL ID FLOW CYTOMETERS AB To determine the precision of cellular fluorescence intensity (FI) measurements derived from labeled microbead standards, FI results were compared from 43 different flow cytometers in 34 laboratories. All laboratories analyzed prepared aliquots of fluoresceinated calf thymocyte nuclei (Fluorotrol), human lymphocytes stained with fluoresceinated anti-CD4 antibody, and fluoresceinated microbeads used as both internal and external standards. Measurements were conducted by most laboratories on the third and fourth days after sample preparation. Results for percent of events within the gates and the histograms returned by participants indicated that the samples had remained stable and that gated populations had been properly identified. All standard curves showed strong linearity, and the pooled results from all standards produced a best-fit curve that was in close agreement with the assigned values. Nonetheless, results for cellular FI were highly variable, with CVs of 20-34%. Agreement within lab/instrument was much better, with CVs ranging from 3.0 to 9.9%. The overall variability was not obviously attributable to differences in the types of cytometer, nor could it be explained by attributes of the standard curves or any other single variable examined. However, the application of a corrective factor based on FI results for Fluorotrol allowed a two-fold improvement in the precision of FI measurements on CD4-stained lymphocytes, with an overall CV of 11%. Uncharacterized differences in the operating conditions of flow cytometers can influence cellular FI measurements, but consistent results can be obtained if a stained cellular calibrator is analyzed in addition to the proper microbead standards. RP VOGT, RF (reprint author), CTR DIS CONTROL,DIV ENVIRONM HLTH LAB SCI,ATLANTA,GA 30333, USA. RI Phillips, Donald/D-5270-2011 NR 11 TC 43 Z9 43 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0196-4763 J9 CYTOMETRY JI Cytometry PY 1991 VL 12 IS 6 BP 525 EP 536 DI 10.1002/cyto.990120609 PG 12 WC Biochemical Research Methods; Cell Biology SC Biochemistry & Molecular Biology; Cell Biology GA GA504 UT WOS:A1991GA50400008 PM 1684930 ER PT J AU EKBOM, A HELMICK, C ZACK, M ADAMI, HO AF EKBOM, A HELMICK, C ZACK, M ADAMI, HO TI ULCERATIVE PROCTITIS IN CENTRAL SWEDEN 1965-1983 - A POPULATION-BASED EPIDEMIOLOGIC-STUDY SO DIGESTIVE DISEASES AND SCIENCES LA English DT Article DE INFLAMMATORY BOWEL DISEASE; ULCERATIVE COLITIS; EPIDEMIOLOGY ID JEWISH POPULATION; CROHNS-DISEASE; DISODIUM-CROMOGLYCATE; COLITIS; PREVALENCE; COMMUNITY AB Ulcerative proctitis has by tradition been regarded as a subgroup of ulcerative colitis. Population-based epidemiological studies of ulcerative proctitis are, however, virtually nonexistent. In an epidemiological study of inflammatory bowel disease in the Uppsala Health Care Region, 1065 cases of ulcerative proctitis were diagnosed from 1965 through 1983. Males predominated, with the male to female ratio 1.4:1. Annual incidence rates were higher in urban than in rural areas. The annual incidence rates increased threefold from 2.8 per 10(5) to 6.6 per 10(5) during the period, affecting all age groups over 14 years of age, in both urban and rural areas and in both sexes. Differences in temporal trends and certain other epidemiological characteristics between ulcerative proctitis and extensive ulcerative colitis suggest that ulcerative proctitis is a specific disease whose etiology differs from that of extensive ulcerative colitis. C1 CTR DIS CONTROL,ATLANTA,GA 30333. RP EKBOM, A (reprint author), UNIV HOSP UPPSALA,DEPT SURG,S-75185 UPPSALA,SWEDEN. NR 25 TC 37 Z9 37 U1 0 U2 0 PU PLENUM PUBL CORP PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 SN 0163-2116 J9 DIGEST DIS SCI JI Dig. Dis. Sci. PD JAN PY 1991 VL 36 IS 1 BP 97 EP 102 DI 10.1007/BF01300095 PG 6 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA ER626 UT WOS:A1991ER62600019 PM 1985012 ER PT J AU KHOURY, MJ AF KHOURY, MJ TI PASSIVE SMOKING - A REPLY SO ENVIRONMENT INTERNATIONAL LA English DT Letter RP KHOURY, MJ (reprint author), CTR ENVIRONM HLTH & INJURY CONTROL,BIRTH DEFECTS & GENET DIS BRANCH,ATLANTA,GA 30333, USA. NR 0 TC 1 Z9 1 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0160-4120 J9 ENVIRON INT JI Environ. Int. PY 1991 VL 17 IS 4 BP 381 EP 381 DI 10.1016/0160-4120(91)90027-N PG 1 WC Environmental Sciences SC Environmental Sciences & Ecology GA FN261 UT WOS:A1991FN26100028 ER PT J AU MARGOLICK, JB VOGT, RF AF MARGOLICK, JB VOGT, RF TI ENVIRONMENTAL-EFFECTS ON THE HUMAN IMMUNE-SYSTEM AND THE RISK OF CANCER - FACTS AND FEARS IN THE ERA OF AIDS SO ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS-PART C OF JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH LA English DT Review ID HUMAN-IMMUNODEFICIENCY-VIRUS; PNEUMOCYSTIS-CARINII PNEUMONIA; LYMPHOCYTE-T SUBSETS; LONG-TERM EXPOSURE; PERIPHERAL-BLOOD LYMPHOCYTES; NATURAL-KILLER CELLS; HTLV-III LAV; HIV-INFECTION; ACQUIRED IMMUNODEFICIENCY; HOMOSEXUAL MEN C1 CTR DIS CONTROL,DIV ENVIRONM HLTH LAB SCI,ATLANTA,GA 30333. RP MARGOLICK, JB (reprint author), JOHNS HOPKINS UNIV HOSP,SCH HYG & PUBL HLTH,DEPT ENVIRONM HLTH SCI,DIV TOXICOL SCI,BALTIMORE,MD 21205, USA. NR 193 TC 0 Z9 0 U1 0 U2 0 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 1059-0501 J9 ENVIRON CARCIN ECO R JI Environ. Carcinog. Ecotoxical. Rev.-Pt. C J. Env. Sci. Health PY 1991 VL 9 IS 2 BP 155 EP 206 PG 52 WC Oncology; Environmental Sciences; Toxicology SC Oncology; Environmental Sciences & Ecology; Toxicology GA HW404 UT WOS:A1991HW40400001 ER PT J AU SCHULTE, P MAZZUCKELLI, LF AF SCHULTE, P MAZZUCKELLI, LF TI VALIDATION OF BIOLOGICAL MARKERS FOR QUANTITATIVE RISK ASSESSMENT SO ENVIRONMENTAL HEALTH PERSPECTIVES LA English DT Article ID ETHYLENE-OXIDE; EPIDEMIOLOGIC RESEARCH; EXPOSURE; HEMOGLOBIN; DNA AB The evaluation of biological markers is recognized as necessary to the future of toxicology, epidemiology, and quantitative risk assessment. For biological markers to become widely accepted, their validity must be ascertained. This paper explores the range of considerations that compose the concept of validity as it applies to the evaluation of biological markers. Three broad categories of validity (measurement, internal study, and external) are discussed in the context of evaluating data for use in quantitative risk assessment. Particular attention is given to importance of measurement validity in the consideration of whether to use biological markers in epidemiologic studies. The concepts developed in this presentation are applied to examples derived from the occupational environment. In the first example, measurement of bromine release as a marker of ethylene dibromide toxicity is shown to be of limited use in constructing an accurate quantitative assessment of the risk of developing cancer as a result of long-term, low-level exposure. This example is compared to data obtained from studies of ethylene oxide, in which hemoglobin alkylation is shown to be a valid marker of both exposure and effect. RP SCHULTE, P (reprint author), NIOSH,INDUSTRYWIDE STUDIES BRANCH,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 43 TC 22 Z9 22 U1 0 U2 1 PU NATL INST ENVIRON HEALTH SCI PI RES TRIANGLE PK PA PO BOX 12233, RES TRIANGLE PK, NC 27709 SN 0091-6765 J9 ENVIRON HEALTH PERSP JI Environ. Health Perspect. PD JAN PY 1991 VL 90 BP 239 EP 246 DI 10.2307/3430874 PG 8 WC Environmental Sciences; Public, Environmental & Occupational Health; Toxicology SC Environmental Sciences & Ecology; Public, Environmental & Occupational Health; Toxicology GA FD603 UT WOS:A1991FD60300037 PM 2050067 ER PT J AU HOGUE, CJR BREWSTER, MA AF HOGUE, CJR BREWSTER, MA TI THE POTENTIAL OF EXPOSURE BIOMARKERS IN EPIDEMIOLOGIC STUDIES OF REPRODUCTIVE HEALTH SO ENVIRONMENTAL HEALTH PERSPECTIVES LA English DT Article ID D-GLUCARIC ACID; URINARY THIOETHER EXCRETION; HANDLING CYTOSTATIC DRUGS; TAR CIGARETTE SMOKERS; SPRAGUE-DAWLEY RATS; OCCUPATIONAL EXPOSURE; MERCAPTURIC ACIDS; AMNIOTIC-FLUID; BIOLOGICAL MARKERS; MUTAGENIC ACTIVITY AB To further the development and application of exposure markers in field investigations in reproductive epidemiology, we have synthesized recent examinations of the issues surrounding exposure measurements in reproductive epidemiology. The specific goals of this paper are to define exposure biomarkers and explore their potential uses, particularly as screening tools. The tests for glucaric acid, thioethers, mutagenicity, and porphyrin patterns meet the general criteria for useful exposure screens. For certain xenobiotic agents, these tests accurately differentiate exposure levels, as demonstrated in occupational and environmental epidemiologic studies. As urinary screens, they are noninvasive and applicable on a large scale with current laboratory techniques. For short-term exposure, glucaric acid, thioethers, and mutagenicity tests are useful. Porphyrin patterns may measure cumulative effects as well as current exposure levels. The usefulness of these tests in epidemiologic studies of environmental effects on reproductive health has yet to be studied. To do so, the battery must be standardized for pregnant women, and test results must be correlated with measured adverse reproductive outcomes, such as gestational length and birthweight. This correlation is particularly important because maternal exposure rather than fetal exposure is being measured. The extent to which xenobiotic chemicals cross the placental barrier may vary greatly depending on the type of exposures, timing in pregnancy, and maternal detoxification capability. Without better exposure measures, epidemiologic studies of reproductive health probably will not successfully identify xenobiotic fetotoxic agents in the environment. However, with an adequate battery of nonspecific exposure biomarkers, prospective studies of environmental effects on pregnancy outcomes might be possible. To narrow the list of potential exposures, these prospective studies could be followed by case-control studies of more specific biomarkers directed at suspect exposures. C1 CHILDRENS HOSP,METAB LAB,804 WOLFE ST,LITTLE ROCK,AR 72201. CTR DIS CONTROL,DIV REPROD HLTH,ATLANTA,GA 30333. ARKANSAS CHILDRENS HOSP,LITTLE ROCK,AR 72201. UNIV ARKANSAS MED SCI HOSP,DEPT PATHOL,LITTLE ROCK,AR 72201. UNIV ARKANSAS MED SCI HOSP,DEPT PEDIAT,LITTLE ROCK,AR 72201. NR 123 TC 8 Z9 8 U1 0 U2 1 PU NATL INST ENVIRON HEALTH SCI PI RES TRIANGLE PK PA PO BOX 12233, RES TRIANGLE PK, NC 27709 SN 0091-6765 J9 ENVIRON HEALTH PERSP JI Environ. Health Perspect. PD JAN PY 1991 VL 90 BP 261 EP 269 DI 10.2307/3430877 PG 9 WC Environmental Sciences; Public, Environmental & Occupational Health; Toxicology SC Environmental Sciences & Ecology; Public, Environmental & Occupational Health; Toxicology GA FD603 UT WOS:A1991FD60300040 PM 2050070 ER PT J AU KHLAT, M KHOURY, M AF KHLAT, M KHOURY, M TI INBREEDING AND DISEASES - DEMOGRAPHIC, GENETIC, AND EPIDEMIOLOGIC PERSPECTIVES SO EPIDEMIOLOGIC REVIEWS LA English DT Review ID CONSANGUINEOUS MARRIAGES; SOUTH-INDIA; PREREPRODUCTIVE MORTALITY; PARENTAL CONSANGUINITY; REPRODUCTIVE WASTAGE; POPULATION; LOAD; FERTILITY; MORBIDITY; JAPAN C1 CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333. RP KHLAT, M (reprint author), INST NATL ETUD DEMOGR,UNITE METHODES PAYS DEV,27 RUE COMMANDEUR,F-75675 PARIS 14,FRANCE. NR 139 TC 53 Z9 53 U1 0 U2 1 PU JOHNS HOPKINS UNIV SCHOOL HYGIENE PUB HEALTH PI BALTIMORE PA 111 MARKET PLACE, STE 840, BALTIMORE, MD 21202-6709 SN 0193-936X J9 EPIDEMIOL REV JI Epidemiol. Rev. PY 1991 VL 13 BP 28 EP 41 PG 14 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA GY359 UT WOS:A1991GY35900002 PM 1765114 ER PT J AU GRIFFIN, PM TAUXE, RV AF GRIFFIN, PM TAUXE, RV TI THE EPIDEMIOLOGY OF INFECTIONS CAUSED BY ESCHERICHIA-COLI O157-H7, OTHER ENTEROHEMORRHAGIC ESCHERICHIA-COLI, AND THE ASSOCIATED HEMOLYTIC UREMIC SYNDROME SO EPIDEMIOLOGIC REVIEWS LA English DT Review ID SHIGA-LIKE-TOXIN; THROMBOTIC THROMBOCYTOPENIC PURPURA; CYTOTOXIN-PRODUCING STRAINS; VEROTOXIN-PRODUCING STRAIN; BUFFALO CALF DIARRHEA; HEMORRHAGIC COLITIS; CYTO-TOXIN; DNA PROBES; SEROTYPE O157-H7; RISK-FACTORS RP GRIFFIN, PM (reprint author), US DEPT HHS,CTR DIS CONTROL,NATL CTR INFECT DIS,DIV BACTERIAL & MYCOT DIS,ENTER DIS BRANCH,ATLANTA,GA 30333, USA. NR 225 TC 1374 Z9 1416 U1 6 U2 104 PU JOHNS HOPKINS UNIV SCHOOL HYGIENE PUB HEALTH PI BALTIMORE PA 111 MARKET PLACE, STE 840, BALTIMORE, MD 21202-6709 SN 0193-936X J9 EPIDEMIOL REV JI Epidemiol. Rev. PY 1991 VL 13 BP 60 EP 98 PG 39 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA GY359 UT WOS:A1991GY35900004 PM 1765120 ER PT J AU SCHUCHAT, A BROOME, CV AF SCHUCHAT, A BROOME, CV TI TOXIC SHOCK SYNDROME AND TAMPONS SO EPIDEMIOLOGIC REVIEWS LA English DT Article ID STAPHYLOCOCCUS-AUREUS; RISK-FACTORS; PRODUCTION INVITRO; SYRINGE METHOD; SURVEILLANCE; ASSOCIATION; FEATURES RP SCHUCHAT, A (reprint author), CTR DIS CONTROL,NATL CTR INFECT DIS,DIV BACTERIAL & MYCOT DIS,ATLANTA,GA 30333, USA. NR 33 TC 11 Z9 11 U1 0 U2 2 PU JOHNS HOPKINS UNIV SCHOOL HYGIENE PUB HEALTH PI BALTIMORE PA 111 MARKET PLACE, STE 840, BALTIMORE, MD 21202-6709 SN 0193-936X J9 EPIDEMIOL REV JI Epidemiol. Rev. PY 1991 VL 13 BP 99 EP 112 PG 14 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA GY359 UT WOS:A1991GY35900005 PM 1662639 ER PT J AU HOGE, CW BREIMAN, RF AF HOGE, CW BREIMAN, RF TI ADVANCES IN THE EPIDEMIOLOGY AND CONTROL OF LEGIONELLA INFECTIONS SO EPIDEMIOLOGIC REVIEWS LA English DT Review ID NOSOCOMIAL LEGIONNAIRES-DISEASE; INDIRECT IMMUNOFLUORESCENCE ASSAY; WATER DISTRIBUTION-SYSTEMS; PONTIAC FEVER; GUINEA-PIGS; URINARY ANTIGEN; PNEUMOPHILA CONTAMINATION; LABORATORY DIAGNOSIS; 2 OUTBREAKS; DNA PROBE C1 CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL & MYCOT DIS,RESP DIS BRANCH,1600 CLIFTON RD NE,ATLANTA,GA 30333. NR 156 TC 54 Z9 56 U1 2 U2 4 PU JOHNS HOPKINS UNIV SCHOOL HYGIENE PUB HEALTH PI BALTIMORE PA 111 MARKET PLACE, STE 840, BALTIMORE, MD 21202-6709 SN 0193-936X J9 EPIDEMIOL REV JI Epidemiol. Rev. PY 1991 VL 13 BP 329 EP 340 PG 12 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA GY359 UT WOS:A1991GY35900015 PM 1765117 ER PT J AU LINDEGREN, ML FEHRS, LJ HADLER, SC HINMAN, AR AF LINDEGREN, ML FEHRS, LJ HADLER, SC HINMAN, AR TI UPDATE - RUBELLA AND CONGENITAL-RUBELLA SYNDROME, 1980-1990 SO EPIDEMIOLOGIC REVIEWS LA English DT Article ID UNITED-STATES; ANTIBODY-RESPONSES; IMMUNIZATION; REINFECTION; PREGNANCY; VACCINATION; INFECTION; OUTBREAK; MEASLES; ELIMINATION RP LINDEGREN, ML (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,DIV IMMUNIZAT,INFORMAT SERV,MAILSTOP E06,ATLANTA,GA 30333, USA. NR 54 TC 23 Z9 24 U1 0 U2 1 PU JOHNS HOPKINS UNIV SCHOOL HYGIENE PUB HEALTH PI BALTIMORE PA 111 MARKET PLACE, STE 840, BALTIMORE, MD 21202-6709 SN 0193-936X J9 EPIDEMIOL REV JI Epidemiol. Rev. PY 1991 VL 13 BP 341 EP 348 PG 8 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA GY359 UT WOS:A1991GY35900016 PM 1765118 ER PT J AU BERAL, V JAFFE, H WEISS, R AF BERAL, V JAFFE, H WEISS, R TI CANCER SURVEYS - CANCER, HIV AND AIDS SO EUROPEAN JOURNAL OF CANCER LA English DT Article C1 INST CANC RES,CHESTER BEATTY LABS,LONDON,ENGLAND. CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,ATLANTA,GA 30333. RP BERAL, V (reprint author), RADCLIFFE INFIRM,OXFORD OX2 6HE,ENGLAND. RI Beral, Valerie/B-2979-2013 NR 2 TC 16 Z9 18 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0959-8049 J9 EUR J CANCER JI Eur. J. Cancer PY 1991 VL 27 IS 8 BP 1057 EP 1058 DI 10.1016/0277-5379(91)90281-H PG 2 WC Oncology SC Oncology GA GC833 UT WOS:A1991GC83300030 PM 1832894 ER PT J AU GRAVES, LM SWAMINATHAN, B REEVES, MW WENGER, J AF GRAVES, LM SWAMINATHAN, B REEVES, MW WENGER, J TI RIBOSOMAL DNA FINGERPRINTING OF LISTERIA-MONOCYTOGENES USING A DIGOXIGENIN-LABELED DNA PROBE SO EUROPEAN JOURNAL OF EPIDEMIOLOGY LA English DT Note DE LISTERIA-MONOCYTOGENES; RIBOSOMAL DNA FINGERPRINTING; NONISOTOPIC DNA PROBE; DIGOXIGENIN AB A nonisotopic ribosomal DNA fingerprinting technique was developed for the characterization of Listeria monocytogenes. Plasmid pKK3535 (a pBR322-derived plasmid containing rrnB ribosomal RNA operon of Escherichia coli) was labeled with digoxigenin-11-dUTP by random priming and used to probe EcoRI fragments of L. monocytogenes chromosomal DNA on nylon filters. The method was successfully applied to the characterization of two sets of patient and food isolates of L. monocytogenes. RP GRAVES, LM (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,MENINGITIS & SPECIAL PATHOGENS BRANCH,ATLANTA,GA 30333, USA. NR 0 TC 41 Z9 41 U1 0 U2 2 PU KLUWER ACADEMIC PUBL PI DORDRECHT PA SPUIBOULEVARD 50, PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS SN 0393-2990 J9 EUR J EPIDEMIOL JI Eur. J. Epidemiol. PD JAN PY 1991 VL 7 IS 1 BP 77 EP 82 PG 6 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EU939 UT WOS:A1991EU93900009 PM 1902798 ER PT J AU MILLET, P COLLINS, WE ATKINSON, CT CAMPBELL, GH BRODERSON, JR BROWN, BG FILIPSKI, V AIKAWA, M NGUYENDINH, P AF MILLET, P COLLINS, WE ATKINSON, CT CAMPBELL, GH BRODERSON, JR BROWN, BG FILIPSKI, V AIKAWA, M NGUYENDINH, P TI PLASMODIUM-CYNOMOLGI - IMMUNIZATION OF A RHESUS-MONKEY WITH EXOERYTHROCYTIC STAGES CULTURED IN AUTOLOGOUS HEPATOCYTES SO EXPERIMENTAL PARASITOLOGY LA English DT Article DE PLASMODIUM-CYNOMOLGI; MACACA-MULATTA; EXOERYTHROCYTIC STAGES; INVITRO; PRIMARY CULTURE; AUTOLOGOUS HEPATOCYTES; IMMUNIZATION; ANTIBODY RESPONSE; EXOERYTHROCYTIC (EE); PHOSPHATE-BUFFERED SALINE (PBS); INDIRECT FLUORESCENT ANTIBODY (IFA); FALCON ASSAY SCREENING TEST (FAST); ENZYME-LINKED IMMUNOSORBENT ASSAY (ELISA); MONOCLONAL ANTIBODIES (MABS); CIRCUMSPOROZOITE (CS); KILODALTON (KDA) ID SPOROZOITES; ANTIBODIES; KNOWLESI C1 CTR DIS CONTROL,CTR INFECT DIS,SCI RESOURCES PROGRAM,ATLANTA,GA 30333. CASE WESTERN RESERVE UNIV,INST PATHOL,CLEVELAND,OH 44106. RP MILLET, P (reprint author), CTR DIS CONTROL,DIV PARASIT DIS,MALARIA BRANCH,ATLANTA,GA 30333, USA. FU NIAID NIH HHS [AI-10645] NR 13 TC 5 Z9 5 U1 0 U2 0 PU ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 SN 0014-4894 J9 EXP PARASITOL JI Exp. Parasitol. PD JAN PY 1991 VL 72 IS 1 BP 91 EP 98 DI 10.1016/0014-4894(91)90125-G PG 8 WC Parasitology SC Parasitology GA ER333 UT WOS:A1991ER33300012 PM 1993467 ER PT J AU KHOURY, MJ FLANDERS, WD LIPTON, RB DORMAN, JS AF KHOURY, MJ FLANDERS, WD LIPTON, RB DORMAN, JS TI THE AFFECTED SIB-PAIR METHOD IN THE CONTEXT OF AN EPIDEMIOLOGIC-STUDY DESIGN - COMMENTARY SO GENETIC EPIDEMIOLOGY LA English DT Note DE EPIDEMIOLOGIC METHODS; FAMILIAL GENETIC; SIB-PAIR METHOD ID IBD DISTRIBUTION; COMPETING RISKS; LINKAGE; DISEASES AB The purpose of this commentary is to provide a framework for using the well-known sib-pair methodology in the context of epidemiologic study designs. Using examples from the Pittsburgh family studies of insulin-dependent diabetes mellitus, we illustrate that the sib-pair method can be used in family-based epidemiologic studies. In a cohort study, unaffected relatives of probands ascertained from well-defined populations are followed for disease development. Disease risks are then stratified according to the number of alleles at one or more loci (0, 1, 2) that are identical by descent (ibd) with the proband. In the absence of linkage between the marker locus and the disease locus, disease risks are expected to be identical in the three groups. Measures of relative risk can be computed (with share-0 as baseline group). In a case-control study, relatives of probands that become affected (cases) are compared to a sample of relatives of probands that stay unaffected (controls) with respect to the number of alleles ibd with the proband. Measures of odds ratio can be computed (with share-0 as baseline group). In both cohort and case-control approaches, covariates including other genetic markers and environmental exposures can be evaluated in relation to disease risk and also for evidence of interaction with the specific marker of interest using stratified and multivariate analyses. Family-based epidemiologic studies allow investigators to study, in a single design, the role of environmental factors and specific gene loci in the etiology of diseases. C1 EMORY UNIV,SCH PUBL HLTH,DIV EPIDEMIOL,ATLANTA,GA 30322. LOYOLA UNIV,MED CTR,DEPT PREVENT MED & EPIDEMIOL,MAYWOOD,IL 60153. UNIV PITTSBURGH,GRAD SCH PUBL HLTH,DEPT EPIDEMIOL,PITTSBURGH,PA 15260. RP KHOURY, MJ (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333, USA. NR 28 TC 17 Z9 17 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0741-0395 J9 GENET EPIDEMIOL JI Genet. Epidemiol. PY 1991 VL 8 IS 4 BP 277 EP 282 DI 10.1002/gepi.1370080408 PG 6 WC Genetics & Heredity; Mathematical & Computational Biology SC Genetics & Heredity; Mathematical & Computational Biology GA GN915 UT WOS:A1991GN91500007 PM 1756950 ER PT J AU FLANDERS, WD KHOURY, MJ AF FLANDERS, WD KHOURY, MJ TI EXTENSIONS TO METHODS OF SIB-PAIR LINKAGE ANALYSES SO GENETIC EPIDEMIOLOGY LA English DT Article DE LINKAGE ANALYSES; EPIDEMIOLOGIC METHODS; GENETIC EPIDEMIOLOGY ID MATCHED CASE-CONTROL; COMPETING RISKS; DISEASE; TRAITS; COHORT AB Sib-pair methods provide simple, robust, easily implemented ways to screen for linkage between a marker locus and a suspected disease susceptibility locus. The basic analysis reflects the idea that, in the presence of linkage, siblings who share more alleles at the marker locus should also tend to be concordant for disease. Available sib-pair methods do not lead directly to estimates of risk associated with nongenetic factors, may not account for a variable age-at-onset, or may require that the age-at-onset distribution be known. In this paper, we propose a method for sib-pair linkage analyses that allows for a variable age-at-onset using a logistic model, easily allows modelling of nongenetic factors, reflects the correlation of sibs within a sibship, and allows for nonzero risk in those without the susceptibility genotype. Based on a limited number of simulations, the method has as good or better power than another recently described method that also allows for a variable C1 CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333. RP FLANDERS, WD (reprint author), EMORY UNIV,SCH PUBL HLTH,DIV EPIDEMIOL,1599 CLIFTON RD,ATLANTA,GA 30329, USA. NR 20 TC 13 Z9 13 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0741-0395 J9 GENET EPIDEMIOL JI Genet. Epidemiol. PY 1991 VL 8 IS 6 BP 399 EP 408 DI 10.1002/gepi.1370080606 PG 10 WC Genetics & Heredity; Mathematical & Computational Biology SC Genetics & Heredity; Mathematical & Computational Biology GA HF696 UT WOS:A1991HF69600005 PM 1806409 ER PT J AU KHOURY, MJ WATERS, GD MARTIN, ML EDMONDS, LD AF KHOURY, MJ WATERS, GD MARTIN, ML EDMONDS, LD TI ARE OFFSPRING OF WOMEN WITH HEREDITARY HEMATOLOGIC DISORDERS AT INCREASED RISK OF CONGENITAL CARDIOVASCULAR MALFORMATIONS SO GENETIC EPIDEMIOLOGY LA English DT Article DE CARDIOVASCULAR MALFORMATIONS; HEMATOLOGIC DISORDERS ID HEART-DISEASE AB Hereditary hematologic disorders (HHD) have been reported in excess among infants and families of infants with congenital cardiovascular malformations (CCM) compared with controls, suggesting possible common pathogenetic mechanisms. It is plausible that hemodynamic changes during pregnancy associated with HHD could affect cardiac morphogenesis. To investigate whether offspring of women with selected HHD have an excess risk of CCM, the authors examined data from a nationwide birth defects monitoring program (BDMP) covering about 2.9 million births in the United States between 1982 and 1988. The system ascertains major birth defects diagnosed in the newborn period. An anonymous linkage procedure linked maternal obstetric records with newborn records using demographic, diagnostic, and geographic variables. A total of 1,239 mothers were identified with selected HHD (47 hereditary spherocytosis, 575 thalassemias, 310 sickle cell anemia, 88 other hereditary hemolytic anemias, 159 von Willebrand disease, and 60 other congenital coagulopathies). In all, 14 infants received a newborn discharge diagnosis of CCM (expected number based on population rates of CCM from the same hospitals and time period is 7.74; P = 0.0268). No single CCM entity accounted for this excess. In contrast, 8 infants had major non-CCM defects (expected number 7.46; P = 0.466). These data suggest an excess risk of CCM among off-spring of women with selected HHD. Further studies are needed to explore these findings and to evaluate the pathogenetic significance of this association. RP KHOURY, MJ (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333, USA. NR 14 TC 2 Z9 2 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0741-0395 J9 GENET EPIDEMIOL JI Genet. Epidemiol. PY 1991 VL 8 IS 6 BP 417 EP 423 DI 10.1002/gepi.1370080608 PG 7 WC Genetics & Heredity; Mathematical & Computational Biology SC Genetics & Heredity; Mathematical & Computational Biology GA HF696 UT WOS:A1991HF69600007 PM 1806411 ER PT J AU MOOPENN, WF HINE, TK JOHNSON, MH JUE, DL PIERSMA, H THERRELL, B CHU, A AF MOOPENN, WF HINE, TK JOHNSON, MH JUE, DL PIERSMA, H THERRELL, B CHU, A TI HB LUXEMBOURG [ALPHA-24(B5)TYR-]HIS], HB MAPUTO [BETA-47(CD6)ASP-]TYR], AND HB FUKUYAMA [BETA-77(EF1)HIS-]TYR] SO HEMOGLOBIN LA English DT Note ID PERFORMANCE LIQUID-CHROMATOGRAPHY; HEMOGLOBIN; SEPARATION; VARIANT; CHAINS C1 DIAKONESSEN HOSP,9721 SW GRONINGEN,NETHERLANDS. TEXAS DEPT HLTH,DIV CHEM SERV,AUSTIN,TX 78756. CARDINAL GLENNON HOSP,ST LOUIS,MO 63104. RP MOOPENN, WF (reprint author), CTR DIS CONTROL,CTR INFECT DIS,ATLANTA,GA 30333, USA. NR 10 TC 5 Z9 5 U1 0 U2 0 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0363-0269 J9 HEMOGLOBIN JI Hemoglobin PY 1991 VL 15 IS 1-2 BP 97 EP 101 DI 10.3109/03630269109072488 PG 5 WC Biochemistry & Molecular Biology; Hematology SC Biochemistry & Molecular Biology; Hematology GA FR808 UT WOS:A1991FR80800009 PM 1917540 ER PT J AU ABOURZIK, NN CONLON, M ZORDON, G HINE, TK JOHNSON, MH JUE, DL MOOPENN, WF AF ABOURZIK, NN CONLON, M ZORDON, G HINE, TK JOHNSON, MH JUE, DL MOOPENN, WF TI HB ST FRANCIS [BETA-121(GH4)GLU-]GLY] - A NEW MUTATION AT THE SAME SITE AS HB D-LOS ANGELES SO HEMOGLOBIN LA English DT Note C1 CONNECTICUT DEPT HLTH SERV,HARTFORD,CT 06105. CTR DIS CONTROL,CTR INFECT DIS,ATLANTA,GA 30333. CTR DIS CONTROL,DEPT MED,HEMATOL LAB,ATLANTA,GA 30333. RP ABOURZIK, NN (reprint author), ST FRANCIS HOSP,CTR DIABET CARE,HARTFORD,CT 06105, USA. NR 10 TC 6 Z9 6 U1 0 U2 0 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0363-0269 J9 HEMOGLOBIN JI Hemoglobin PY 1991 VL 15 IS 1-2 BP 115 EP 117 DI 10.3109/03630269109072491 PG 3 WC Biochemistry & Molecular Biology; Hematology SC Biochemistry & Molecular Biology; Hematology GA FR808 UT WOS:A1991FR80800012 PM 1917532 ER PT B AU HADLER, SC DEMONZON, MA BENSABATH, G DURAN, MM SCHATZ, G FIELDS, HA AF HADLER, SC DEMONZON, MA BENSABATH, G DURAN, MM SCHATZ, G FIELDS, HA BE GERIN, JL PURCELL, RH RIZZETTO, M TI EPIDEMIOLOGY OF HEPATITIS-DELTA VIRUS-INFECTION IN LESS-DEVELOPED-COUNTRIES SO HEPATITIS DELTA VIRUS SE PROGRESS IN CLINICAL AND BIOLOGICAL RESEARCH LA English DT Proceedings Paper CT 3RD INTERNATIONAL SYMP ON HEPATITIS DELTA VIRUS CY OCT 26-28, 1989 CL WASHINGTON, DC SP GEORGETOWN UNIV, MED CTR, NIAID, NIH, OSPEDALE MOLINETTE, ABBOTT LAB, IMMUNO, SCHERING PLOUGH, SK&F, SORIN BIOMEDICA, WELLCOME FDN RP HADLER, SC (reprint author), CTR DIS CONTROL,COLLABORAT HEPATITIS CTR,HEPATITIS BRANCH,ATLANTA,GA 30333, USA. NR 0 TC 11 Z9 11 U1 0 U2 0 PU WILEY-LISS, INC PI NEW YORK PA NEW YORK BN 0-471-56073-1 J9 PROG CLIN BIOL RES JI Prog.Clin.Biol.Res. PY 1991 VL 364 BP 21 EP 31 PG 11 WC Medicine, Research & Experimental; Virology SC Research & Experimental Medicine; Virology GA BT15R UT WOS:A1991BT15R00002 PM 2020698 ER PT J AU BLACK, CM MCDOUGAL, JS EVATT, BL REIMER, CB AF BLACK, CM MCDOUGAL, JS EVATT, BL REIMER, CB TI HUMAN MARKERS FOR IGG2 AND IGG4 APPEAR TO BE ON THE SAME MOLECULE IN THE CHIMPANZEE SO IMMUNOLOGY LA English DT Article ID MONOCLONAL-ANTIBODIES; NONHUMAN-PRIMATES; IMMUNOGLOBULIN; SUBCLASSES; EPITOPES; REGION; GENES AB It has been reported that all four immunoglobulin G (IgG) subclasses present in human serum are also present in chimpanzee serum, as detected with antibodies specific for the human IgG subclasses. We used monoclonal antibodies (mAb) specific for human IgG subclasses to measure concentrations of the four subclasses in chimpanzee sera. Initial ELISA studies indicated that epitopes for all four human subclasses are present in chimpanzee sera. The concentrations of IgG1, IgG2 and IgG3 were similar in human and chimpanzee sera, but the registered concentrations of IgG4 were different. Absorption of IgG2-reactive material from chimpanzee serum with IgG2 mAb resulted in removal of IgG4-reactive material as well. Conversely, absorption of IgG4-reactive material removed IgG2-reactive material. IgG2-reactive material, isolated from chimpanzee serum using solid-phase anti-IgG2 mAb, reacted with anti-IgG4 mAb, and isolated IgG4-reactive material reacted with anti-IgG2 mAb. Three anti-IgG2 mAb and five anti-IgG4 mAb, each of which react with separate epitopes on their respective human isotype, were used in these studies. We conclude that chimpanzee serum contains only three IgG isotypes related to those of humans, one of which contains determinants related to both human IgG2 and IgG4. C1 CTR DIS CONTROL,DIV IMMUNOL ONCOL & HEMATOL DIS,BLDG 1,ROOM 1354,A25,ATLANTA,GA 30333. NR 17 TC 7 Z9 7 U1 0 U2 0 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0019-2805 J9 IMMUNOLOGY JI Immunology PD JAN PY 1991 VL 72 IS 1 BP 94 EP 98 PG 5 WC Immunology SC Immunology GA EU945 UT WOS:A1991EU94500016 PM 1997405 ER PT J AU BURROUGHS, GE HUEBENER, DJ AF BURROUGHS, GE HUEBENER, DJ TI DEVELOPMENT OF A THIN-FILM ENVIRONMENTAL MONITOR SO INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY LA English DT Article DE ENVIRONMENTAL MONITOR; REAL TIME MONITOR; AMMONIA; MERCURY; INVENTION RP BURROUGHS, GE (reprint author), NIOSH,4676 PKWY,CINCINNATI,OH 45226, USA. NR 20 TC 1 Z9 1 U1 1 U2 1 PU GORDON BREACH SCI PUBL LTD PI READING PA C/O STBS LTD PO BOX 90, READING, BERKS, ENGLAND RG1 8JL SN 0306-7319 J9 INT J ENVIRON AN CH JI Int. J. Environ. Anal. Chem. PY 1991 VL 44 IS 1 BP 21 EP 39 DI 10.1080/03067319108027535 PG 19 WC Chemistry, Analytical; Environmental Sciences SC Chemistry; Environmental Sciences & Ecology GA FR504 UT WOS:A1991FR50400003 ER PT J AU WACHSMUTH, IK KIEHLBAUCH, JA BOPP, CA CAMERON, DN STROCKBINE, NA WELLS, JG BLAKE, PA AF WACHSMUTH, IK KIEHLBAUCH, JA BOPP, CA CAMERON, DN STROCKBINE, NA WELLS, JG BLAKE, PA TI THE USE OF PLASMID PROFILES AND NUCLEIC-ACID PROBES IN EPIDEMIOLOGIC INVESTIGATIONS OF FOODBORNE, DIARRHEAL DISEASES SO INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY LA English DT Article DE C.JEJUNI; ESCHERICHIA-COLI; S ENTERITIDES; DNA RIBOSOMAL-RNA PROBE; PLASMID DNA; MOLECULAR EPIDEMIOLOGY ID ESCHERICHIA-COLI SEROTYPE; BACTERIAL GENOMIC DNA; SALMONELLA-ENTERITIDIS; GUANIDIUM THIOCYANATE; CAMPYLOBACTER-JEJUNI; RAPID EXTRACTION; TYPHIMURIUM; INFECTIONS; OUTBREAKS; IDENTIFICATION AB The application of nucleic acid analyses to investigations of infectious disease outbreaks has resulted in useful molecular strain markers that distinguish the epidemic clone of a particular pathogen and help identify specific vehicles of infection. We have successfully used plasmid profile analysis, restriction endonuclease digestion of plasmid and whole-cell DNAs, and nucleic acid hybridization to investigate recent outbreaks of foodborne diarrheal illness. Plasmid analysis has been important in identifying epidemic strains of Salmonella enteritidis and Escherichia coli O157:H7. In a culture survey of S. enteritidis isolates from humans and a variety of animals, including chickens and chicken eggs, we identified 16 distinct plasmid profiles and used these to differentiate strains, especially within commonly occurring phage types (Colindale 8 and 13a). Hind III digests of plasmid DNA were useful in distinguishing plasmids of similar mass but dissimilar enzyme target sequences; they clearly distinguished S. enteritidis strains causing systemic infections in children in parts of Africa from U.S. isolates. Investigations of outbreaks of hemorrhagic colitis have also been assisted by plasmid analysis. Restriction endonuclease digests of whole-cell DNA and Southern blot analysis, hybridizing with E. coli 16S and 23S rRNA (ribotyping), have been effective subtyping techniques, especially for plasmidless isolates of Campylobacter jejuni. In five outbreaks of C. jejuni infections, ribotyping of PvuII and ClaI digests distinguished individual epidemic strains within one commonly occurring C. jejuni serotype (Penner 2, Lior 4). Preliminary data show that ribotyping of NcoI digests can also distinguish individual epidemic strains of E. coli O157:H7 and may provide a more stable marker than plasmid profiles. Specific DNA probes derived from cloned virulence genes of E. coli have been invaluable in epidemic investigations and surveys. Using colony hybridization, we found in one survey of stool specimens from 174 dairy cattle that 11% of animals were asymptomatically carrying Shiga-like toxigenic E. coli other than O157:H7. We also found that newly synthesized oligonucleotide probes for the Shiga-like toxins I and II agreed 100% with cloned gene probes in a study of 613 E. coli strains. Future studies of these organisms will include the use of additional synthetic oligonucleotides as primers to amplify the toxin genes directly in patient and animal specimens by the polymerase chain reaction. There is a continuing and expanding role for molecular approaches in epidemiological investigations. The DNA methods described above are not based on the often complex expression of phenotypic characteristics, and, unlike sensitive and specific techniques such as phage typing, a single method can be used to study a variety of Gram-positive and negative bacterial pathogens. RP WACHSMUTH, IK (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,ENTER DIS BRANCH,BLDG 1,ROOM 5035,MAILSTOP COG,ATLANTA,GA 30333, USA. NR 34 TC 42 Z9 45 U1 1 U2 5 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0168-1605 J9 INT J FOOD MICROBIOL JI Int. J. Food Microbiol. PD JAN PY 1991 VL 12 IS 1 BP 77 EP 90 DI 10.1016/0168-1605(91)90049-U PG 14 WC Food Science & Technology; Microbiology SC Food Science & Technology; Microbiology GA FA169 UT WOS:A1991FA16900007 PM 2018708 ER PT J AU MARTIN, RE GREENE, RE AF MARTIN, RE GREENE, RE TI CHOOSING AMONG ALTERNATIVE FACILITY LOCATIONS SO INTERNATIONAL JOURNAL OF PUBLIC ADMINISTRATION LA English DT Article RP MARTIN, RE (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 5 TC 0 Z9 0 U1 0 U2 0 PU MARCEL DEKKER INC PI NEW YORK PA 270 MADISON AVE, NEW YORK, NY 10016 SN 0190-0692 J9 INT J PUBLIC ADMIN PY 1991 VL 14 IS 2 BP 143 EP 148 DI 10.1080/01900699108524709 PG 6 WC Public Administration SC Public Administration GA EV344 UT WOS:A1991EV34400003 ER PT B AU MAHY, BWJ DYKEWICZ, C FISHERHOCH, S OSTROFF, S TIPPLE, M SANCHEZ, A AF MAHY, BWJ DYKEWICZ, C FISHERHOCH, S OSTROFF, S TIPPLE, M SANCHEZ, A GP INT ASSOC BIOL STANDARDIZAT TI VIRUS ZOONOSES AND THEIR POTENTIAL FOR CONTAMINATION OF CELL-CULTURES SO INTERNATIONAL SYMPOSIUM ON VIROLOGICAL ASPECTS OF THE SAFETY OF BIOLOGICAL PRODUCTS SE DEVELOPMENTS IN BIOLOGICAL STANDARDIZATION LA English DT Proceedings Paper CT INTERNATIONAL SYMP ON VIROLOGICAL ASPECTS OF THE SAFETY OF BIOLOGICAL PRODUCTS CY NOV 08-09, 1990 CL ZOOL SOC LONDON, LONDON, ENGLAND SP ARES SERONO SYMP HO ZOOL SOC LONDON RP MAHY, BWJ (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,ATLANTA,GA 30333, USA. NR 0 TC 14 Z9 14 U1 0 U2 1 PU KARGER PI BASEL PA BASEL BN 3-8055-5467-2 J9 DEV BIOLOGICALS JI Dev. Biols PY 1991 VL 75 BP 183 EP 189 PG 7 WC Biology; Medicine, Research & Experimental; Virology SC Life Sciences & Biomedicine - Other Topics; Research & Experimental Medicine; Virology GA BU82W UT WOS:A1991BU82W00021 PM 1794619 ER PT J AU SHIP, JA WOLFF, A SELIK, RM AF SHIP, JA WOLFF, A SELIK, RM TI EPIDEMIOLOGY OF ACQUIRED-IMMUNE-DEFICIENCY-SYNDROME IN PERSONS AGED 50 YEARS OR OLDER SO JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY LA English DT Article DE EPIDEMIOLOGY; AGED POPULATION ID HUMAN IMMUNODEFICIENCY VIRUS; INCUBATION PERIOD; UNITED-STATES; AIDS; TRANSFUSION; INFECTION; TRANSMISSION; HEMOPHILIA; RISKS AB Acquired immune deficiency syndrome (AIDS) has afflicted persons of all ages, yet only recently has attention been devoted to AIDS in older persons. To examine the epidemiology of AIDS in persons greater-than-or-equal-to 50 years old in the United States, we analyzed cases reported to the Centers for Disease Control. The number reported annually in persons greater-than-or-equal-to 50 years old increased from 13 in 1981 to 3,562 in 1989. Through December 1989, 11,984 had been reported, representing 10% of all cases. Although male homosexual contact accounted for most cases in persons aged 50-69, blood transfusion became a more common means of exposure with increasing age, accounting for 28% of cases in persons aged 60-69 and 64% of cases in individuals aged greater-than-or-equal-to 70. The proportion of women increased from 6.1% in persons with AIDS aged 50-59 to 28.7% of those aged greater-than-or-equal-to 70. The proportion of AIDS diagnoses made in the same month as death increased from 16% in persons aged 50-59 to 37% in those aged greater-than-or-equal-to 80, suggesting either more rapid progression of disease or increasing delay in diagnosis. As the incidence in older persons continues to increase, clinicians caring for older patients must become more familiar with AIDS. C1 CTR DIS CONTROL,AIDS PROGRAM,SURVEILLANCE,ATLANTA,GA 30333. RP SHIP, JA (reprint author), NIDR,CLIN INVEST & PATIENT CARE BRANCH,9000 ROCKVILLE PIKE,BLDG 10,BETHESDA,MD 20892, USA. NR 32 TC 91 Z9 95 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 1077-9450 J9 J ACQ IMMUN DEF SYND JI J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. PY 1991 VL 4 IS 1 BP 84 EP 88 PG 5 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA EP176 UT WOS:A1991EP17600012 PM 1984059 ER PT J AU BEHETS, FM EDIDI, B QUINN, TC ATIKALA, L BISHAGARA, K NZILA, N LAGA, M PIOT, P RYDER, RW BROWN, CC AF BEHETS, FM EDIDI, B QUINN, TC ATIKALA, L BISHAGARA, K NZILA, N LAGA, M PIOT, P RYDER, RW BROWN, CC TI DETECTION OF SALIVARY HIV-1-SPECIFIC IGG ANTIBODIES IN HIGH-RISK POPULATIONS IN ZAIRE SO JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY LA English DT Article DE SALIVA; HIV 1-SPECIFIC IGG ANTIBODIES; ELISA; WESTERN BLOT; SEROPREVALENCE; SEROINCIDENCE; KINSHASA, ZAIRE ID HIV AB Saliva and blood samples were tested for human immunodeficiency virus-1 (HIV-1) antibodies in two high-risk populations in Kinshasa, Zaire. In a seroprevalence study of 458 sexually transmitted disease (STD) clinic attendees, 142 of 145 seropositive individuals had enzyme-linked immunosorbent assay (ELISA)-positive saliva samples (97.9% sensitivity). All saliva samples from seronegative patients were ELISA-negative (100% specificity). Of the 142 ELISA-positive saliva specimens, 137 were also Western blot-positive (94.5% sensitivity). In a subsequent seroincidence study of 315 initially seronegative female prostitutes followed during 183 woman-years of observation, 9 of 14 women who seroconverted (7.7% seroincidence) had ELISA-positive saliva samples at the time seroconversion was detected. Only three of these saliva specimens could be confirmed by Western blot. Although salivary testing for HIV-1 antibodies using conventional assays was not sensitive in detecting recent seroconversions, screening of salivary samples for HIV-1 antibody provides a convenient alternative method for conducting seroprevalence surveys in populations in whom venipuncture is not possible or convenient. C1 PROJECT SIDA,KINSHASA,ZAIRE. INST TROP MED,ANTWERP,BELGIUM. NIAID,IMMUNOREGULAT LAB,BETHESDA,MD 20892. CTR DIS CONTROL,ATLANTA,GA 30333. NR 11 TC 49 Z9 49 U1 2 U2 5 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 1077-9450 J9 J ACQ IMMUN DEF SYND JI J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. PY 1991 VL 4 IS 2 BP 183 EP 187 PG 5 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA EU101 UT WOS:A1991EU10100013 PM 1987355 ER PT J AU BUTERA, ST PEREZ, VL BESANSKY, NJ WU, BY NABEL, GJ FOLKS, TM AF BUTERA, ST PEREZ, VL BESANSKY, NJ WU, BY NABEL, GJ FOLKS, TM TI AN EPISOMALLY MAINTAINED HIV-1 GENOME CAN ACUTELY INFECT SUSCEPTIBLE CELLS IN CULTURE SO JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,RETROVIRUS DIS BRANCH,ATLANTA,GA 30333. UNIV MICHIGAN,MED CTR,HOWARD HUGHES MED INST,DEPT INTERNAL MED,ANN ARBOR,MI 48109. UNIV MICHIGAN,MED CTR,HOWARD HUGHES MED INST,DEPT BIOL CHEM,ANN ARBOR,MI 48109. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 1077-9450 J9 J ACQ IMMUN DEF SYND JI J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. PY 1991 VL 4 IS 3 BP 331 EP 332 PG 2 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA EY269 UT WOS:A1991EY26900078 ER PT J AU ROWE, T LAIRMORE, MD POWELL, J ANSARI, AA LAL, R FOLKS, TM AF ROWE, T LAIRMORE, MD POWELL, J ANSARI, AA LAL, R FOLKS, TM TI SUPPRESSION OF HIV-1 REPLICATION IN CD4+ T-CELLS BY A SOLUBLE FACTOR(S) PRODUCED BY A CD8+ HTLV-I+ CELL-LINE SO JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,RETROVIRUS DIS BRANCH,ATLANTA,GA 30333. EMORY UNIV,SCH MED,DEPT PATHOL,ATLANTA,GA 30322. OHIO STATE UNIV,DEPT VET PATHOBIOL,COLUMBUS,OH 43210. NR 0 TC 0 Z9 0 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 1077-9450 J9 J ACQ IMMUN DEF SYND JI J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. PY 1991 VL 4 IS 3 BP 336 EP 337 PG 2 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA EY269 UT WOS:A1991EY26900089 ER PT J AU HARDY, AM BUEHLER, JW AF HARDY, AM BUEHLER, JW TI CHARACTERIZATION OF LONG-TERM SURVIVORS OF ACQUIRED-IMMUNODEFICIENCY-SYNDROME SO JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY LA English DT Article DE SURVIVAL ID LYMPHADENOPATHY; VIRUS AB Of 4,073 reported patients diagnosed with AIDS from 1978 through 1983, 821 (20%) were not reported to be dead by January 1987. Of these apparent long-term survivors, 780 (95%) were reported from 14 states or from local areas where collaborating health departments conducted special follow-up investigations: 119 (15%) were found to be alive, 475 (61%) were dead, and 186 (24%) were lost to follow-up. Health departments obtained consent to collect additional clinical and laboratory information on 48 of the living patients. Six (13%) had no laboratory evidence specific for human immunodeficiency virus (HIV) infection (antibody, antigen, viral isolation, or polymerase chain reaction assay); 41 (85%) had a positive result on at least one test; and one was not tested. Of the 41 infected patients, 25 (61%) had Kaposi's sarcoma (KS) and two (5%) had Pneumocystis carinii pneumonia as the only AIDS-indicative disease; the remainder had multiple diseases. CD4+ cell counts were low (< 30% of total T lymphocytes) by the time of enrollment in 34 (87%) of 39 patients tested. When enrolled survivors with KS were compared with KS patients who had died within 2 years after AIDS diagnosis, survivors were less likely to have had other diseases in addition to KS than were nonsurvivors (31% versus 51%). While overall mortality by 1987 for patients diagnosed in 1978-83 was high (92-96%), a small number have survived and were doing relatively well clinically, despite evidence of continued CD4+ cell depression. C1 CTR DIS CONTROL,CID,DIV HIV AIDS,MS-E47,ATLANTA,GA 30333. NR 22 TC 27 Z9 27 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 1077-9450 J9 J ACQ IMMUN DEF SYND JI J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. PY 1991 VL 4 IS 4 BP 386 EP 391 PG 6 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA FC522 UT WOS:A1991FC52200005 PM 2007973 ER PT J AU HOLMBERG, SD GERBER, AR STEWART, JA BYERS, RH NAHMIAS, AJ AF HOLMBERG, SD GERBER, AR STEWART, JA BYERS, RH NAHMIAS, AJ TI HERPES-SIMPLEX VIRUS TYPE-2 AND HIV SEROCONVERSION SO JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY LA English DT Letter ID HOMOSEXUAL MEN; INFECTION; ASSOCIATION C1 EMORY UNIV,SCH MED,ATLANTA,GA 30322. RP HOLMBERG, SD (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,ATLANTA,GA 30333, USA. NR 6 TC 5 Z9 5 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 1077-9450 J9 J ACQ IMMUN DEF SYND JI J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. PY 1991 VL 4 IS 7 BP 732 EP 733 PG 2 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA FR760 UT WOS:A1991FR76000012 PM 1646875 ER PT J AU HARRISON, LH DASILVA, APJ GAYLE, HD ALBINO, P GEORGE, R LEETHOMAS, S RAYFIELD, MA DELCASTILLO, F HEYWARD, WL AF HARRISON, LH DASILVA, APJ GAYLE, HD ALBINO, P GEORGE, R LEETHOMAS, S RAYFIELD, MA DELCASTILLO, F HEYWARD, WL TI RISK-FACTORS FOR HIV-2 INFECTION IN GUINEA-BISSAU SO JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY LA English DT Article DE HIV-2; GUINEA-BISSAU; RISK FACTORS ID HUMAN IMMUNODEFICIENCY VIRUS; TYPE-2; AFRICA; AIDS AB To define the epidemiology of HIV-2 infection, we conducted a case-control study among hospitalized patients at an acute care hospital in Bissau, Guinea-Bissau, a country with endemic HIV-2 infection. Among 128 patients with various diagnoses, 23 (18%) were positive for HIV-2 by ELISA and Western blot. One of these patients was serologically reactive for HIV-1 also, but PCR and viral culture revealed the presence of HIV-2 only. To study risk factors, behaviors, and AIDS knowledge related to the acquisition of HIV infection, 22 HIV-2-seropositive and 21 seronegative hospitalized patients were given a physical examination and administered a questionnaire. Among women, transfusion was associated with HIV-2 infection (OR = 14.4, p = 0.02); among men, sex with a prostitute was the principal risk factor (OR = undefined, p = 0.02). Although 79% of HIV-infected patients and controls had heard of AIDS, only 17% of all study participants and 50% of males reporting sex with prostitutes had used condoms in the previous year. These data suggest that the risk factors for HIV-2 infection are similar to those for HIV-1 and support previous studies showing that HIV-2 is the predominant HIV in Guinea-Bissau. Efforts to decrease transmission of HIV-2 should include screening for HIV-2 in blood for transfusion in endemic areas (now done in Bissau) and education about the risk of sexual transmission. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,ATLANTA,GA 30333. MINIST PUBL HLTH,BISSAU,GUINEA BISSAU. WHO,GLOBAL PROGRAMME AIDS,CH-1211 GENEVA 27,SWITZERLAND. RP HARRISON, LH (reprint author), JOHNS HOPKINS UNIV,SCH HYG & PUBL HLTH,DEPT INT HLTH,615 N WOLFE ST,ROOM 5515,BALTIMORE,MD 21205, USA. NR 15 TC 6 Z9 6 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 1077-9450 J9 J ACQ IMMUN DEF SYND JI J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. PY 1991 VL 4 IS 11 BP 1155 EP 1160 PG 6 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA GN380 UT WOS:A1991GN38000012 PM 1753343 ER PT J AU LAL, RB RUDOLPH, DL FOLKS, TM HOOPER, C AF LAL, RB RUDOLPH, DL FOLKS, TM HOOPER, C TI ROLE OF INSULIN-LIKE GROWTH FACTOR-I IN SPONTANEOUS PROLIFERATION OF HTLV-INFECTED LYMPHOCYTES SO JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY LA English DT Letter ID FACTOR-I C1 CTR DIS CONTROL,DIV IMMUNOL ONCOL & HEMATOL DIS,ATLANTA,GA 30333. RP LAL, RB (reprint author), CTR DIS CONTROL,RETROVIRUS DIS BRANCH,ATLANTA,GA 30333, USA. NR 7 TC 2 Z9 2 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 1077-9450 J9 J ACQ IMMUN DEF SYND JI J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. PY 1991 VL 4 IS 11 BP 1165 EP 1166 PG 2 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA GN380 UT WOS:A1991GN38000017 PM 1684388 ER PT J AU KARON, JM BERKELMAN, RL AF KARON, JM BERKELMAN, RL TI THE GEOGRAPHIC AND ETHNIC DIVERSITY OF AIDS INCIDENCE TRENDS IN HOMOSEXUAL BISEXUAL MEN IN THE UNITED-STATES SO JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY LA English DT Article DE HIV; EPIDEMIOLOGY; HOMOSEXUAL BISEXUAL MEN; UNITED-STATES ID IMMUNODEFICIENCY VIRUS-INFECTION; SAN-FRANCISCO; HEPATITIS-B; RATES; EPIDEMIC AB We examined geographic and racial/ethnic variation in acquired immune deficiency syndrome (AIDS) incidence in homosexual and bisexual men (i.e., men who report sex with men: MSWM) not using i.v. drugs in the United States. The AIDS incidence in these men has continued to increase in the United States. Incidence increased much less rapidly after 1986 in the three metropolitan statistical areas (MSAs) with the most cases, New York City, Los Angeles, and San Francisco, and may have reached a plateau in these areas. This change in incidence occurred in non-Hispanic black and Hispanic MSWM as well as in non-Hispanic whites in these MSAs, but earlier in whites. There have been similar changes in incidence (but later in time) in all other MSAs with a population of at least 1,000,000 combined, with more tendency toward a plateau in whites than in non-whites. In contrast, incidence increased linearly through 1989 in MSAs with a population < 1,000,000 and in rural areas, with no change in trend after 1986. Changes in human immunodeficiency virus (HIV) infection incidence before 1985, better therapy and medical care, and migration all contributed to these changes in incidence, as may have changes in reporting. Continued HIV seroconversions among MSWM show that efforts to prevent HIV infection must be continued in all areas of the United States. RP KARON, JM (reprint author), CTR DIS CONTROL,DIV HIV AIDS E-48,ATLANTA,GA 30333, USA. NR 32 TC 26 Z9 26 U1 1 U2 2 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 1077-9450 J9 J ACQ IMMUN DEF SYND JI J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. PY 1991 VL 4 IS 12 BP 1179 EP 1189 PG 11 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA GR659 UT WOS:A1991GR65900003 PM 1941525 ER PT J AU MONTEITH, RS WARREN, CW CACERES, JM GOLDBERG, HI AF MONTEITH, RS WARREN, CW CACERES, JM GOLDBERG, HI TI CHANGES IN CONTRACEPTIVE USE AND FERTILITY - EL-SALVADOR, 1978-88 SO JOURNAL OF BIOSOCIAL SCIENCE LA English DT Article ID DETERMINANTS AB In El Salvador from 1978 to 1988, contraceptive use among married women 15-44 years of age increased from 34% to 47%, and the total fertility rate declined from 6.3 to 4.6 children per woman. Most of this change took place from 1978 to 1985. Sterilization is the most prevalent method used, but nearly one-half of the women who are sterilized did not use any contraception before their operation. Few young couples use reversible methods of contraception to space births or delay the start of childbearing. On average, women wait 8 years after marriage and have nearly three children before they use contraception. C1 ASOCIAC DEMOGRAT SALVADORENA,SAN SALVADOR,EL SALVADOR. RP MONTEITH, RS (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV REPROD HLTH,PUBL HLTH SERV,ATLANTA,GA 30333, USA. NR 13 TC 2 Z9 2 U1 0 U2 1 PU GALTON FOUNDATION PI COLCHESTER PA P O BOX 32 COMMERCE WAY, COLCHESTER, ESSEX, ENGLAND CO2 8HP SN 0021-9320 J9 J BIOSOC SCI JI J. Biosoc. Sci. PD JAN PY 1991 VL 23 IS 1 BP 79 EP 89 PG 11 WC Demography; Public, Environmental & Occupational Health; Social Sciences, Biomedical SC Demography; Public, Environmental & Occupational Health; Biomedical Social Sciences GA EU017 UT WOS:A1991EU01700010 PM 1999451 ER PT J AU BURKMAN, RT LEE, NC ORY, HW RUBIN, GL AF BURKMAN, RT LEE, NC ORY, HW RUBIN, GL TI THE INTRAUTERINE-DEVICE AND PELVIC INFLAMMATORY DISEASE - THE WOMENS HEALTH STUDY REANALYZED - RESPONSE SO JOURNAL OF CLINICAL EPIDEMIOLOGY LA English DT Article C1 DEPT HLTH NEW S WALES,SYDNEY,AUSTRALIA. CTR DIS CONTROL,ATLANTA,GA 30333. RP BURKMAN, RT (reprint author), HENRY FORD HOSP,DEPT OBSTET & GYNECOL,DETROIT,MI 48202, USA. NR 5 TC 6 Z9 7 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0895-4356 J9 J CLIN EPIDEMIOL JI J. Clin. Epidemiol. PY 1991 VL 44 IS 2 BP 123 EP 125 DI 10.1016/0895-4356(91)90260-G PG 3 WC Health Care Sciences & Services; Public, Environmental & Occupational Health SC Health Care Sciences & Services; Public, Environmental & Occupational Health GA EY989 UT WOS:A1991EY98900003 PM 1995773 ER PT J AU MURPHY, LR AF MURPHY, LR TI JOB DIMENSIONS ASSOCIATED WITH SEVERE DISABILITY DUE TO CARDIOVASCULAR-DISEASE SO JOURNAL OF CLINICAL EPIDEMIOLOGY LA English DT Article DE CARDIOVASCULAR DISEASE; SEVERE DISABILITY; OCCUPATION; JOB DIMENSIONS; JOB ANALYSIS; WORKER CONTROL ID POSITION ANALYSIS QUESTIONNAIRE; HEALTH; STRESS; STRAIN; EPIDEMIOLOGY; WORKERS; DEMANDS AB This study explored associations among job activities and disability due to cardiovascular disease by merging national disability data with independently-obtained job activity data. Disability data were taken from a 1978 U.S. health interview survey (n = 9855). Expert ratings of job activities (dimensions) were obtained from a job analysis database (n = 2485 occupations). The two databases were merged such that job dimension data were imputed to each occupation in the disability database. Odds ratios for cardiovascular disability were calculated for scores in the second, third, and fourth quartiles for each of the 32 job dimensions, using scores in the first quartile as the standard. Job dimensions associated with cardiovascular disability were (a) hazardous situations; (b) vigilant work and responsibility for others; (c) exchanging job-related information; and (d) attention to devices. Occupations identified with high scores on these job dimensions included transportation jobs (air traffic controllers, airline pilots and attendants, bus drivers, locomotive engineers, truck drivers), teachers (preschool, adult education), and craftsmen/foremen (machinists, carpenters, and foremen). RP MURPHY, LR (reprint author), NIOSH,DIV BIOMED & BEHAV SCI,APPL PSYCHOL & ERGONOM BRANCH,CINCINNATI,OH 45226, USA. NR 30 TC 32 Z9 32 U1 0 U2 2 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0895-4356 J9 J CLIN EPIDEMIOL JI J. Clin. Epidemiol. PY 1991 VL 44 IS 2 BP 155 EP 166 DI 10.1016/0895-4356(91)90263-9 PG 12 WC Health Care Sciences & Services; Public, Environmental & Occupational Health SC Health Care Sciences & Services; Public, Environmental & Occupational Health GA EY989 UT WOS:A1991EY98900006 PM 1825324 ER PT J AU CHU, SY LEE, NC WINGO, PA SENIE, RT GREENBERG, RS PETERSON, HB AF CHU, SY LEE, NC WINGO, PA SENIE, RT GREENBERG, RS PETERSON, HB TI THE RELATIONSHIP BETWEEN BODY-MASS AND BREAST-CANCER AMONG WOMEN ENROLLED IN THE CANCER AND STEROID-HORMONE STUDY SO JOURNAL OF CLINICAL EPIDEMIOLOGY LA English DT Article DE BREAST CANCER; BODY MASS; OBESITY; ESTROGENS; CASE CONTROL ID POSTMENOPAUSAL WOMEN; RISK-FACTORS; RELATIVE WEIGHT; SEX-HORMONES; ADULT LIFE; HEIGHT; EPIDEMIOLOGY; POPULATION; ETIOLOGY; OBESITY AB We examined the relationship between body mass [weight (kg)/height (m)2] and breast cancer using data from the Cancer and Steroid Hormone Study. The study compared 4323 women aged 20-54 years with newly diagnosed breast cancer identified through population-based tumor registries with 4358 women randomly selected from the general population of the same geographic areas. Among naturally menopausal women, risk of breast cancer increased with increasing body mass index (BMI); those severely overweight (BMI greater-than-or-equal-to 32.30) had nearly 3-fold higher risk of breast cancer compared with women in the leanest category (BMI < 20.00). This positive association appeared stronger with increasing years since menopause and in women who had ever used estrogen replacement therapy. A positive association between body mass and breast cancer risk also was observed among premenopausal women; however, risk estimates were substantially lower. Substantial weight gain from adolescence to adulthood was a more important risk factor than lifelong obesity. Prevalence of obesity increases with age; our results suggest that interventions that prevent this trend could have an important effect on breast cancer risk, especially during the menopausal years. C1 CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV REPROD HLTH CTR,ATLANTA,GA 30333. EMORY UNIV,SCH MED,DEPT EPIDEMIOL & BIOSTAT,ATLANTA,GA 30329. NR 49 TC 81 Z9 81 U1 3 U2 3 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0895-4356 J9 J CLIN EPIDEMIOL JI J. Clin. Epidemiol. PY 1991 VL 44 IS 11 BP 1197 EP 1206 DI 10.1016/0895-4356(91)90152-Y PG 10 WC Health Care Sciences & Services; Public, Environmental & Occupational Health SC Health Care Sciences & Services; Public, Environmental & Occupational Health GA GP825 UT WOS:A1991GP82500009 PM 1941014 ER PT J AU ANDREWS, JS AF ANDREWS, JS TI DOES GOOD PEER-REVIEW ASSURE GOOD EPIDEMIOLOGY SO JOURNAL OF CLINICAL EPIDEMIOLOGY LA English DT Article; Proceedings Paper CT CONF ON ETHICS AND EPIDEMIOLOGY CY JUN 12-13, 1989 CL BIRMINGHAM, AL SP IND EPIDEMIOL FORUM, DUPONT DE EPIDEMIOLOGY; ETHICS; PEER REVIEW; RESEARCH AB The American public requires that research projects use resources efficiently, that they provide answers that are beneficial, and that they are carried out ethically. Peer review of research protocols, results, and reports, provides one way to improve research and to reassure the public. RP ANDREWS, JS (reprint author), US PHS,AGCY TOX SUBST & DIS REGISTRY,ATLANTA,GA, USA. NR 0 TC 1 Z9 1 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0895-4356 J9 J CLIN EPIDEMIOL JI J. Clin. Epidemiol. PY 1991 VL 44 SU 1 BP S131 EP S134 PG 4 WC Health Care Sciences & Services; Public, Environmental & Occupational Health SC Health Care Sciences & Services; Public, Environmental & Occupational Health GA FP046 UT WOS:A1991FP04600024 PM 2030384 ER PT J AU SCHULTE, PA AF SCHULTE, PA TI ETHICAL ISSUES IN THE COMMUNICATION OF RESULTS SO JOURNAL OF CLINICAL EPIDEMIOLOGY LA English DT Article; Proceedings Paper CT CONF ON ETHICS AND EPIDEMIOLOGY CY JUN 12-13, 1989 CL BIRMINGHAM, AL SP IND EPIDEMIOL FORUM, DUPONT DE EPIDEMIOLOGIC RESEARCH; ETHICS; NOTIFICATION; MEDICAL TESTS ID RIGHT-TO-KNOW; HIGH-RISK; WORKERS; NOTIFICATION AB The communication of the results of medical tests used in epidemiologic studies or the results of such studies involve ethical issues. These issues range from the rights of subjects to receive these results to the obligation of investigators to communicate clearly and entirely not only the results but their meaning. This can be problematic in epidemiologic studies where biological or medical monitoring yields uncertain findings. Generally, the results of epidemiologic studies are group-oriented and have limited meaning for the individual. It is incumbent on investigators to express this limitation. The investigators may also have a responsibility to alert any subject with clinical conditions that require immediate or long-term follow-up. RP SCHULTE, PA (reprint author), NIOSH,INDUSTRYWIDE STUDIES BRANCH,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 23 TC 14 Z9 14 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0895-4356 J9 J CLIN EPIDEMIOL JI J. Clin. Epidemiol. PY 1991 VL 44 SU 1 BP S57 EP S61 PG 5 WC Health Care Sciences & Services; Public, Environmental & Occupational Health SC Health Care Sciences & Services; Public, Environmental & Occupational Health GA FP046 UT WOS:A1991FP04600012 PM 2030397 ER PT J AU MOSS, DM MATHEWS, HM VISVESVARA, GS DICKERSON, JW WALKER, EM AF MOSS, DM MATHEWS, HM VISVESVARA, GS DICKERSON, JW WALKER, EM TI PURIFICATION AND CHARACTERIZATION OF GIARDIA-LAMBLIA ANTIGENS IN THE FECES OF MONGOLIAN GERBILS SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article ID ENZYME-IMMUNOASSAY; IDENTIFICATION; COPRODIAGNOSIS; PROTEINS; STOOL AB In a recent study, we identified Giardia lamblia 65- and 70-kDa antigens in the feces of infected Mongolian gerbils. The 65-kDa antigen was from a strain isolated from a human with symptoms of giardiasis, and the 70-kDa antigen was from a strain isolated from a human with no symptoms of giardiasis. In this study, we used preparative electrophoresis and electroelution techniques to purify these antigens to a degree which showed a single discrete protein band on silver-stained polyacrylamide gels. By enzyme-linked immunoelectrotransfer blot, common epitopes on the 65- and 70-kDa antigens were indicated by their cross-reactivity with rabbit anti-65-kDa and anti-70-kDa sera. By indirect immunofluorescence assay, the cysts and trophozoites of the two strains cross-reacted with these sera. Of seven lectins tested, only concanavalin A bound to the 70-kDa antigen, suggesting a glycoprotein, and it possessed a low isoelectric point as assessed by preparative isoelectric focusing. Molecular mass estimations of these antigens by sodium dodecyl sulfate-polyacrylamide gradient gel electrophoresis were similar to the 65- and 70-kDa estimations obtained by native polyacrylamide gradient gel electrophoresis. Although the 65- and 70-kDa antigens proved to be resistant to 100-degrees-C heat and stable in storage for up to 25 months at -20-degrees-C, neither appeared to be the same as a fecal G.lamblia antigen with similar molecular mass found by other investigators. This suggests that variable G.lamblia antigens may be found in the feces of infected humans. RP MOSS, DM (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,ATLANTA,GA 30333, USA. NR 25 TC 14 Z9 14 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD JAN PY 1991 VL 29 IS 1 BP 21 EP 26 PG 6 WC Microbiology SC Microbiology GA EP044 UT WOS:A1991EP04400005 PM 1704383 ER PT J AU KATO, N OU, CY KATO, H BARTLEY, SL BROWN, VK DOWELL, VR UENO, K AF KATO, N OU, CY KATO, H BARTLEY, SL BROWN, VK DOWELL, VR UENO, K TI IDENTIFICATION OF TOXIGENIC CLOSTRIDIUM-DIFFICILE BY THE POLYMERASE CHAIN-REACTION SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article ID HUMAN IMMUNODEFICIENCY VIRUS; THERMOSTABLE DNA-POLYMERASE; LINKED IMMUNOSORBENT-ASSAY; TOXIN-A; ESCHERICHIA-COLI; AMPLIFICATION; SEQUENCES; DIAGNOSIS; COUNTERIMMUNOELECTROPHORESIS; INFECTION AB Toxigenic strains of Clostridium difficile are causative agents of pseudomembranous colitis and antimicrobial agent-associated diarrhea and colitis. The toxigenicity is routinely assayed by using highly sensitive cell cultures. We used a simple and rapid polymerase chain reaction (PCR) assay to differentiate toxigenic and nontoxigenic strains of C. difficile. Two sets of oligonucleotide primer pairs derived from nonrepeating sequences of the toxin A gene were used to amplify 546- and 252-bp DNA fragments. A primer pair derived from repeating sequences of the toxin A gene was used to amplify a 1,266-bp DNA product. Amplified products were visualized by polyacrylamide gel electrophoresis followed by ethidium bromide staining. All 35 cytotoxic strains of C. difficile tested generated the expected amplified DNA. In contrast, none of the 26 noncytotoxic strains tested gave positive results. Although the toxins of C. difficile have been demonstrated to cross-react serologically with the toxins of Clostridium sordellii, we did not detect any amplified DNA in two cytotoxic strains or seven noncytotoxic strains of C. sordellii. PCR was negative in all 30 strains of 20 other Clostridium species. Southern hybridization of Hindlll-digested genomic DNA by use of subgenomic probes showed a single hybridization band in toxigenic strains but not in nontoxigenic strains. PCR appears to be a sensitive and specific assay for the rapid identification of toxigenic C. difficile. Nontoxigenic C. difficile appeared to lack the C. difficile toxin A gene. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,ATLANTA,GA 30333. GIFU UNIV,SCH MED,INST ANAEROB BACTERIOL,GIFU 500,JAPAN. RP KATO, N (reprint author), CTR DIS CONTROL,HOSP INFECT PROGRAM,ANAEROB BACTERIA BRANCH,ATLANTA,GA 30333, USA. NR 30 TC 125 Z9 129 U1 0 U2 6 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD JAN PY 1991 VL 29 IS 1 BP 33 EP 37 PG 5 WC Microbiology SC Microbiology GA EP044 UT WOS:A1991EP04400007 PM 1993763 ER PT J AU ARKO, RJ CHEN, CY SCHALLA, WO SARAFIAN, SK TAYLOR, CL KNAPP, JS MORSE, SA AF ARKO, RJ CHEN, CY SCHALLA, WO SARAFIAN, SK TAYLOR, CL KNAPP, JS MORSE, SA TI BINDING OF S-PROTEIN BY NEISSERIA-GONORRHOEAE AND POTENTIAL ROLE IN INVASION SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article ID DISSEMINATED GONOCOCCAL INFECTION; SERUM BACTERICIDAL ACTIVITY; OUTER-MEMBRANE PROTEIN; SEROLOGICAL CLASSIFICATION; MONOCLONAL-ANTIBODIES; RESISTANCE; VITRONECTIN; COMPLEMENT; STRAINS; CELLS AB An agglutination assay was used to examine the binding of purified human S protein (vitronectin, serum spreading factor) to 201 clinical isolates of Neisseria gonorrhoeae. Strains belonging to the protein IA serovars were significantly (P < 0.001) more reactive in agglutination tests with human S protein and were more serum resistant than strains belonging to the protein IB serovars. The strains from patients with disseminated infections belonged predominantly to the IA serovar (19 of 23) and, with the exception of IA-4 and certain IB serovars, avidly agglutinated with S protein. The serovar IA-4 and IB strains isolated from joint or cerebrospinal fluid failed to agglutinate with S protein and appeared to be less serum resistant than most other IA isolates. Cysteine hydrochloride or 2-mercaptoethanol inhibited agglutination of gonococcal cells by S protein. Two serum-resistant transformants exhibited a moderate increase in agglutination of S protein and a more than twofold increase in resistance to killing by fresh human serum following preincubation with S protein; the serum-sensitive parent strain did not agglutinate S protein, and serum resistance was not increased following preincubation with this protein. Binding of S protein by gonococci may represent a novel pathogenic mechanism that can contribute to serum resistance. C1 CTR DIS CONTROL,DIV LAB SYST,PUBL HLTH PRACTICE PROGRAM OFF,ATLANTA,GA 30333. RP ARKO, RJ (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV SEXUALLY TRANSMITTED DIS LAB RES,ATLANTA,GA 30333, USA. NR 28 TC 10 Z9 10 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD JAN PY 1991 VL 29 IS 1 BP 70 EP 75 PG 6 WC Microbiology SC Microbiology GA EP044 UT WOS:A1991EP04400015 PM 1704384 ER PT J AU ENGLUND, JA ANDERSON, LJ RHAME, FS AF ENGLUND, JA ANDERSON, LJ RHAME, FS TI NOSOCOMIAL TRANSMISSION OF RESPIRATORY SYNCYTIAL VIRUS IN IMMUNOCOMPROMISED ADULTS SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article ID HOSPITAL CROSS-INFECTION; MONOCLONAL-ANTIBODIES; ISOLATION PRECAUTIONS; VIRAL-INFECTION; OUTBREAKS; CHILDREN; STRAINS; EPIDEMIOLOGY; INFANTS; NURSERY AB Respiratory syncytial virus (RSV) isolates obtained from nine infected immunocompromised adult patients hospitalized during two consecutive winters (January through April 1987 and 1988) were collected and analyzed against a panel of monoclonal antibodies by an enzyme immunoassay. The history of the patients' illness, onset of symptoms, and date of initial isolation of virus was correlated with the hospital ward and time of hospitalization. Three patients died of respiratory failure related to RSV infection acquired nosocomially. A cluster of RSV disease in four patients hospitalized simultaneously during the 1987 season was demonstrated to be caused by four antigenically distinct viruses; despite an epidemiologic link among the patients, each had been infected from a different source. The RSV disease in the five immunocompromised adults in 1988 was caused by two distinct strains; three patients were infected with RSV subgroup A/4, and two were infected with RSV subgroup B/2. Combining the epidemiologic and strain characterization studies, none of four patients in 1987 were infected from each other, and two of five patients in 1988 may have been infected, directly or indirectly, from one of the other five. The strain characterization studies demonstrated the potential complexity of RSV nosocomial transmission and the need to consider a number of sources for transmission in developing effective prevention strategies. The three deaths underscore the importance of nosocomial RSV disease and the importance of effective prevention strategies. C1 UNIV MINNESOTA HOSP & CLIN,DEPT LAB MED & PATHOL,MINNEAPOLIS,MN 55455. UNIV MINNESOTA HOSP & CLIN,DEPT PEDIAT,MINNEAPOLIS,MN 55455. UNIV MINNESOTA HOSP & CLIN,DEPT MED,MINNEAPOLIS,MN 55455. CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL DIS,ATLANTA,GA 30333. NR 27 TC 69 Z9 71 U1 0 U2 1 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD JAN PY 1991 VL 29 IS 1 BP 115 EP 119 PG 5 WC Microbiology SC Microbiology GA EP044 UT WOS:A1991EP04400024 PM 1993745 ER PT J AU BOND, WW AF BOND, WW TI DISINFECTION AND ENDOSCOPY - MICROBIAL CONSIDERATIONS SO JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY LA English DT Article ID HEPATITIS-B VIRUS; INACTIVATION; INFECTION RP BOND, WW (reprint author), CTR DIS CONTROL,1-B 341,ATLANTA,GA 30333, USA. NR 28 TC 13 Z9 13 U1 0 U2 1 PU BLACKWELL SCIENCE PI CARLTON PA 54 UNIVERSITY ST, P O BOX 378, CARLTON VICTORIA 3053, AUSTRALIA SN 0815-9319 J9 J GASTROEN HEPATOL JI J. Gastroenterol. Hepatol. PD JAN-FEB PY 1991 VL 6 IS 1 BP 31 EP 36 DI 10.1111/j.1440-1746.1991.tb01140.x PG 6 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA FC330 UT WOS:A1991FC33000004 PM 1883974 ER PT J AU BRADLEY, DW PURDY, MA REYES, GR AF BRADLEY, DW PURDY, MA REYES, GR TI HEPATITIS-E VIRUS GENOME - MOLECULAR-FEATURES, EXPRESSION OF IMMUNOREACTIVE PROTEINS AND SEQUENCE DIVERGENCE SO JOURNAL OF HEPATOLOGY LA English DT Article; Proceedings Paper CT INTERNATIONAL MEETING ON GENETIC HETEROGENEITY OF HEPATITIS VIRUSES : CLINICAL IMPLICATIONS CY APR 05-07, 1991 CL SESTRIERE, ITALY ID TRANSMITTED NON-A; NON-B-HEPATITIS AB The strategy for molecular cloning of hepatitis E virus (HEV), the major etiologic agent of enterically-transmitted non-A, non-B hepatitis, is briefly described. The organization of the HEV genome is discussed and compared to those of two other vertebrate viruses that contain single-stranded, positive-sense, polyadenylated RNA genomes with three overlapping ORFs. Serologic cross-reactivity of expressed proteins and genetic divergence of HEV isolates are also described within the context of sequence variation, type-common epitopes, and type-specific epitopes. C1 GENELABS INC,REDWOOD CITY,CA. RP BRADLEY, DW (reprint author), CTR DIS CONTROL,NCID,DVRD,HEPATITIS BRANCH,MAILSTOP A33,ATLANTA,GA 30333, USA. NR 9 TC 10 Z9 11 U1 0 U2 1 PU MUNKSGAARD INT PUBL LTD PI COPENHAGEN PA 35 NORRE SOGADE, PO BOX 2148, DK-1016 COPENHAGEN, DENMARK SN 0168-8278 J9 J HEPATOL JI J. Hepatol. PY 1991 VL 13 SU 4 BP S152 EP S154 DI 10.1016/0168-8278(91)90049-H PG 3 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA HH596 UT WOS:A1991HH59600037 PM 1822509 ER PT J AU ONORATO, IM MODLIN, JF MCBEAN, AM THOMS, ML LOSONSKY, GA BERNIER, RH AF ONORATO, IM MODLIN, JF MCBEAN, AM THOMS, ML LOSONSKY, GA BERNIER, RH TI MUCOSAL IMMUNITY INDUCED BY ENHANCED-POTENCY INACTIVATED AND ORAL POLIO VACCINES SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID IMMUNIZATION; LIVE AB Oral polio vaccine (OPV) is recommended for routine immunization in the United States in part because of its ability to induce intestinal and pharyngeal immunity to reinfection. Mucosal immunity produced by OPV and enhanced-potency inactivated polio vaccine (E-IPV) was compared by challenging vaccinees with type 1 OPV. Fewer OPV (25%) than E-IPV (63%) vaccinees excreted OPV virus in stool after challenge. The mean stool virus titer was higher and the duration of shedding longer among E-IPV excreters. Only one E-IPV and three OPV vaccinees shed virus in the pharynx after challenge. Prechallenge serum neutralizing antibody levels were not statistically different among E-IPV vaccinees who did and did not shed virus; these levels were much higher than those of OPV vaccinees. Poliovirus-specific IgA levels in stool did not correlate with viral excretion. E-IPV was less effective that OPV in preventing and limiting intestinal infection, even though it induced higher postvaccination serum antibody levels. C1 CTR DIS CONTROL,CTR PREVENT SERV,DIV IMMUNIZAT,ATLANTA,GA 30333. JOHNS HOPKINS UNIV,SCH MED,DEPT PEDIAT,BALTIMORE,MD 21205. JOHNS HOPKINS UNIV,SCH HYG & PUBL HLTH,DEPT INT HLTH,BALTIMORE,MD 21218. UNIV MARYLAND,SCH MED,CTR VACCINE DEV,BALTIMORE,MD 21201. NR 21 TC 144 Z9 146 U1 3 U2 9 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD JAN PY 1991 VL 163 IS 1 BP 1 EP 6 PG 6 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EP678 UT WOS:A1991EP67800001 PM 1845806 ER PT J AU SUTTER, RW MARKOWITZ, LE BENNETCH, JM MORRIS, W ZELL, ER PREBLUD, SR AF SUTTER, RW MARKOWITZ, LE BENNETCH, JM MORRIS, W ZELL, ER PREBLUD, SR TI MEASLES AMONG THE AMISH - A COMPARATIVE-STUDY OF MEASLES SEVERITY IN PRIMARY AND SECONDARY CASES IN HOUSEHOLDS SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID INTENSIVE EXPOSURE; MORTALITY; INFECTION; SALMONELLOSIS; COMMUNITY; RISK AB An outbreak of measles among a predominantly unvaccinated and susceptible Amish population in Lebanon County, Pennsylvania, offered the opportunity to test the hypothesis that secondary cases in households are more severe than primary cases because the former have more intense exposure and receive a greater virus inoculum. Of 130 measles cases reported between April and June 1988, 119 (92%) constituted a study of disease severity. Severity was assessed by determining frequency and duration of symptoms, length of any hospitalization, and number of days in bed. In a univariate analysis, fewer secondary cases had conjunctivitis (relative risk [RR], 0.67; 95% confidence interval [CI], 0.48-0.96) and headache (RR, 0.37; CI, 0.15-0.86), but more had earache (RR, 9.69; CI, 1.8-202.9) compared with primary cases. Secondary cases had a shorter mean duration of coryza (4.0 vs. 5.0 days, Student's t test, P = .08). However, a logistic regression model that matched by family and controlled for age and sex indicated that there were no significant differences in measles severity among primary and secondary cases in households. C1 LEBANON STATE HLTH DEPT,LEBANON,PA. RP SUTTER, RW (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,TECH INFORMAT SERV,DIV IMMUNIZAT,ATLANTA,GA 30333, USA. NR 32 TC 35 Z9 35 U1 1 U2 2 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD JAN PY 1991 VL 163 IS 1 BP 12 EP 16 PG 5 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EP678 UT WOS:A1991EP67800003 PM 1984459 ER PT J AU LAL, RB RUDOLPH, DL LAIRMORE, MD KHABBAZ, RF GARFIELD, M COLIGAN, JE FOLKS, TM AF LAL, RB RUDOLPH, DL LAIRMORE, MD KHABBAZ, RF GARFIELD, M COLIGAN, JE FOLKS, TM TI SEROLOGIC DISCRIMINATION OF HUMAN T-CELL LYMPHOTROPIC VIRUS-INFECTION BY USING A SYNTHETIC PEPTIDE-BASED ENZYME-IMMUNOASSAY SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID HTLV-I INFECTION; MONOCLONAL-ANTIBODY; ENVELOPE PROTEIN; LEUKEMIA; BLOOD; HIV; IDENTIFICATION; POLYMERASE; PREDICTION; SEQUENCE AB Synthetic peptides corresponding with unique regions of the envelope glycoproteins (gp46) of human T cell lymphotropic viruses (HTLVs) were used in an enzyme immunoassay to determine if HTLV-I and -II infections could be discriminated. Two synthetic HTLV-I sequence-derived peptides, Env-1 (amino acids 191-215) and Env-5 (amino acids 242-257), reacted with 92% and 100% of the serum specimens (n = 52) from HTLV-I-infected persons, respectively. Although a small percentage (8.6%) of serum specimens from persons infected with HTLV-II cross-reacted with Env-1, none of these specimens reacted with Env-5. Peptide Env-2 encoded by the envelope region of HTLV-II (amino acids 187-210) reacted with serum speciments from both HTLV-I (94%)- and HTLV-II (74%)-infected patients, whereas Env-6, another HTLV-II peptide (amino acids 238-254), reacted with < 6% of the specimens. Therefore, the Env-5 peptide with amino acid sequence SerProAsnValSerValProSerSerSerSerThuProLeuLeuTyr represents an immunodominant domain of HTLV-I that is recognized by serum antibodies from all HTLV-I-infected persons. Moreover, the Env-5-based ELISA allows a categorical distinction between the closely related HTLV-I and -II infections. C1 NIAID,BIOL RESOURCES BRANCH,BETHESDA,MD 20892. RP LAL, RB (reprint author), CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,RETROVIRUS DIS BRANCH,MAIL STOP G19,ATLANTA,GA 30333, USA. NR 35 TC 55 Z9 55 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD JAN PY 1991 VL 163 IS 1 BP 41 EP 46 PG 6 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EP678 UT WOS:A1991EP67800008 PM 1984475 ER PT J AU SHAFFER, N GRAU, GE HEDBERG, K DAVACHI, F LYAMBA, B HIGHTOWER, AW BREMAN, JG NGUYENDINH, P AF SHAFFER, N GRAU, GE HEDBERG, K DAVACHI, F LYAMBA, B HIGHTOWER, AW BREMAN, JG NGUYENDINH, P TI TUMOR-NECROSIS-FACTOR AND SEVERE MALARIA SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID ACQUIRED IMMUNODEFICIENCY SYNDROME; EXPERIMENTAL CEREBRAL MALARIA; FALCIPARUM-MALARIA; SERUM LEVELS; PLASMODIUM-FALCIPARUM; FACTOR CACHECTIN; FACTOR-ALPHA; CHILDREN; INTERLEUKIN-1; ASSOCIATION AB To investigate the relation of tumor necrosis factor-alpha (TNF-alpha) to Plasmodium flaciparum infection, plasma TNF-alpha concentrations were measured in Zairian children with severe malaria, mild malaria, or other illnesses. The initial geometric mean plasma concentration of TNF-alpha among 61 children with P. falciparum infection, (71 pg/ml) was higher than the level in 26 severely ill, aparasitemic children (10 pg/ml; P < .001). Among 29 parasitemic children, initial geometric mean TNF-alpha levels decreased from 77 to 5 pg/ml (P < .001) at day 7. TNF-alpha levels increased with parasite density and were associated with hyperparasitemia, severe anemia, hypoglycemia, and young age but not with cerebral malaria or fatal outcome. However, TNF-alpha levels were elevated equally in children with cerebral malaria and with other signs of severe malaria. With multiple linear regression, TNF-alpha levels were elevated independently in children with hyperparasitemia (P = .001) and severe anemia (P = .04). In this study, high TNF-alpha levels were associated with several manifestations of severe malaria and were not specific to cerebral malaria. C1 CTR MED UNIV GENEVA,WHO,CTR IMMUNOL RES & TRAINING,DEPT PATHOL,GENEVA,SWITZERLAND. MAMA YEMO HOSP,DEPT PEDIAT,KINSHASA,ZAIRE. RP SHAFFER, N (reprint author), CTR DIS CONTROL,DIV PARASIT DIS,MALARIA BRANCH,ATLANTA,GA 30333, USA. RI Grau, Georges/D-7690-2014 OI Grau, Georges/0000-0002-0442-0462 NR 30 TC 104 Z9 105 U1 0 U2 2 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD JAN PY 1991 VL 163 IS 1 BP 96 EP 101 PG 6 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EP678 UT WOS:A1991EP67800017 PM 1984482 ER PT J AU ARCINIEGA, JL HEWLETT, EL JOHNSON, FD DEFOREST, A WASSILAK, SGF ONORATO, IM MANCLARK, CR BURNS, DL AF ARCINIEGA, JL HEWLETT, EL JOHNSON, FD DEFOREST, A WASSILAK, SGF ONORATO, IM MANCLARK, CR BURNS, DL TI HUMAN SEROLOGIC RESPONSE TO ENVELOPE-ASSOCIATED PROTEINS AND ADENYLATE-CYCLASE TOXIN OF BORDETELLA-PERTUSSIS SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID SERUM ANTIBODY-RESPONSES; ESCHERICHIA-COLI; MONOCLONAL-ANTIBODIES; VIRULENCE FACTORS; COMMON ANTIGEN; BACTERIAL; VACCINATION; INFECTION; HEMOLYSIN; CLONING AB The human serologic response to several envelope-associated proteins and adenylate cyclase toxin of Bordetella pertussis was examined using immunoblot techniques. Antigens recognized by sera from individuals with culture-confirmed pertussis and by sera from infants immunized with three doses of conventional whole-cell pertussis vaccine included a 63,000-Da protein that was shown to be antigenically related to a mycobacterial heat-shock protein. A 29,000-Da protein reacted with sera from convalescent individuals, whereas a 91,000-Da protein reacted with sera from vaccinated individuals. Antibodies to adenylate cyclase toxin were common in sera from individuals diagnosed with pertussis. B. pertussis lipooligosaccharide was also recognized by antibodies in some of these sera. These data suggest that some of these antigens may play a role in immunity to pertussis. C1 UNIV VIRGINIA,MED CTR,SCH MED,CHARLOTTESVILLE,VA 22901. TEMPLE UNIV,HLTH SCI CTR,SCH MED,PHILADELPHIA,PA 19140. CTR DIS CONTROL,ATLANTA,GA 30333. RP ARCINIEGA, JL (reprint author), US FDA,CTR BIOL EVAL & RES,8800 ROCKVILLE PIKE,BETHESDA,MD 20205, USA. FU NIAID NIH HHS [R01-AI18000]; PHS HHS [200-83-613] NR 29 TC 34 Z9 34 U1 1 U2 1 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD JAN PY 1991 VL 163 IS 1 BP 135 EP 142 PG 8 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EP678 UT WOS:A1991EP67800023 PM 1984460 ER PT J AU BENOLDI, D ALINOVI, A POLONELLI, L CONTI, S GERLONI, M AJELLO, L PADHYE, AA DEHOOG, GS AF BENOLDI, D ALINOVI, A POLONELLI, L CONTI, S GERLONI, M AJELLO, L PADHYE, AA DEHOOG, GS TI BOTRYOMYCES-CAESPITOSUS AS AN AGENT OF CUTANEOUS PHEOHYPHOMYCOSIS SO JOURNAL OF MEDICAL AND VETERINARY MYCOLOGY LA English DT Article ID PHAEOSCLERA AB The second known case of a skin infection caused by Botryomyces caespitosus is reported. This case has made it possible to describe the characteristics of this fungus in vivo and to establish it as another agent of phaeohyphomycosis. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL & MYCOT DIS,BLDG 5,B-6C,G-11,ATLANTA,GA 30333. UNIV PARMA,FAC MED & CHIRURG,IST DERMATOL,I-43100 PARMA,ITALY. UNIV PARMA,FAC MED & CHIRURG,IST MICROBIOL,I-43100 PARMA,ITALY. CENT BUR SCHIMMELCULTURE,3740 AG BAARN,NETHERLANDS. RI Conti, Stefania/N-3558-2015 OI Conti, Stefania/0000-0001-9973-8352 NR 6 TC 7 Z9 7 U1 0 U2 0 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0268-1218 J9 J MED VET MYCOL JI J. Med. Vet. Mycol. PY 1991 VL 29 IS 1 BP 9 EP 13 PG 5 WC Mycology SC Mycology GA FH181 UT WOS:A1991FH18100002 PM 2061797 ER PT J AU BISSONNETTE, KW SHARP, NJH DYKSTRA, MH ROBERTSON, IR DAVIS, B PADHYE, AA KAUFMAN, L AF BISSONNETTE, KW SHARP, NJH DYKSTRA, MH ROBERTSON, IR DAVIS, B PADHYE, AA KAUFMAN, L TI NASAL AND RETROBULBAR MASS IN A CAT CAUSED BY PYTHIUM-INSIDIOSUM SO JOURNAL OF MEDICAL AND VETERINARY MYCOLOGY LA English DT Article ID PYTHIOSIS; CRYPTOCOCCOSIS; KETOCONAZOLE AB Nasal and retrobulbar infection caused by the Oomycete Pythium insidiosum is described in a cat. The diagnosis was established on three criteria. The staining of broad, sparsely septate hyphal elements in biopsy tissue using a fluorescein-labelled antiglobulin specific for P. insidiosum, detection of antibodies to P. insidiosum by an immunodiffusion test, and isolation of the aetiological agent in pure culture from the biopsy tissue. Treatment with ketoconazole for 6 weeks resulted in clinical improvement, but proptosis of the left eye slowly appeared after the discontinuation of treatment. This case represents a new host for P. insidiosum, namely, a domestic, shorthaired cat, from North Carolina, U.S.A. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL & MYCOT DIS,ATLANTA,GA 30333. N CAROLINA STATE UNIV,COLL VET MED,DEPT COMPAN ANIM & SPECIAL SPECIES MED,RALEIGH,NC 27606. N CAROLINA STATE UNIV,COLL VET MED,DEPT MICROBIOL PATHOL & PARASITOL,RALEIGH,NC 27606. N CAROLINA STATE UNIV,COLL VET MED,DEPT ANAT PHYSIOL SCI & RADIOL,RALEIGH,NC 27606. NR 18 TC 40 Z9 41 U1 0 U2 0 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0268-1218 J9 J MED VET MYCOL JI J. Med. Vet. Mycol. PY 1991 VL 29 IS 1 BP 39 EP 44 PG 6 WC Mycology SC Mycology GA FH181 UT WOS:A1991FH18100006 PM 1648127 ER PT J AU STANDARD, PG PADHYE, AA KAUFMAN, L AF STANDARD, PG PADHYE, AA KAUFMAN, L TI EXOANTIGEN TEST FOR THE RAPID IDENTIFICATION OF EXOPHIALA-SPINIFERA SO JOURNAL OF MEDICAL AND VETERINARY MYCOLOGY LA English DT Note ID DEMATIACEOUS FUNGI; SUBCUTANEOUS PHAEOHYPHOMYCOSIS; JEANSELMEI; DIFFERENTIATION; DERMATITIDIS AB Exophiala spinifera, one of the etiologic agents of subcutaneous phaeohyphomycosis, may be wrongly identified as Exophiala jeanselmei because of the morphologic similarity of the two species. A reagent containing a precipitin specific for E. spinifera was produced by absorbing antiserum to E. spinifera with E. jeanselmei serotype 1 antigen. Using this absorbed antiserum, we were able to correctly identify isolates of E. spinifera and differentiate them from those of Exophiala alcalophila, E. jeanselmei (serotypes 1, 2 and 3), Exophiala moniliae, Exophiala pisciphila, Exophiala salmonis, Phaeoannellomyces werneckii and Wangiella dermatitidis. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL & MYCOT DIS,MYCOT DIS BRANCH,BLDG 5,RM B-6C,G-11,ATLANTA,GA 30333. NR 17 TC 4 Z9 4 U1 0 U2 0 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0268-1218 J9 J MED VET MYCOL JI J. Med. Vet. Mycol. PY 1991 VL 29 IS 4 BP 273 EP 277 PG 5 WC Mycology SC Mycology GA GD952 UT WOS:A1991GD95200008 PM 1719180 ER PT J AU SIDES, EH BENSON, JD PADHYE, AA AF SIDES, EH BENSON, JD PADHYE, AA TI PHEOHYPHOMYCOTIC BRAIN-ABSCESS DUE TO OCHROCONIS-GALLOPAVUM IN A PATIENT WITH MALIGNANT-LYMPHOMA OF A LARGE CELL TYPE SO JOURNAL OF MEDICAL AND VETERINARY MYCOLOGY LA English DT Article ID DACTYLARIA-GALLOPAVA; ENCEPHALITIS; EFFLUENTS; INFECTION; FUNGI AB A 60-year-old man with a 9-year history of malignant lymphoma developed an initial pulmonary infection with Nocardia asteroides which later disseminated to the central nervous system with multiple brain abscesses. He was treated successfully with intravenous trimethoprim-sulfamethoxazole for 6 weeks. A follow-up computed tomography (CT) scan showed complete resolution of the abscesses. Two years later, he returned to the hospital with a 2-week history of confusion, loss of concentration, ataxia, and leaning to the left. A CT scan revealed an enhancing multiloculated complex right frontal lesion. Craniotomy revealed a large right frontal lobe abscess, which was totally resected. Histopathologic examination of the resected tissue revealed multiple, lightly pigmented, septate, branched hyphal elements typical of phaeohyphomycosis. The fungal isolate cultured from the tissue was a dematiaceous, thermotolerant fungus that was identified as Ochroconis gallopavum. Despite treatment with amphotericin B, flucytosine and fluconazole, the patient gradually deteriorated and died. This case represents the third fatal infection, the second from the southeastern United States, due to O. gallopavum. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL & MYCOT DIS,MYCOT DIS BRANCH,BLDG 5,RM B13-G11,ATLANTA,GA 30333. REX HOSP,RALEIGH,NC. NR 17 TC 40 Z9 42 U1 0 U2 1 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0268-1218 J9 J MED VET MYCOL JI J. Med. Vet. Mycol. PY 1991 VL 29 IS 5 BP 317 EP 322 PG 6 WC Mycology SC Mycology GA GH546 UT WOS:A1991GH54600005 PM 1955951 ER PT J AU GARGEYA, IB PRUITT, WR MEYER, SA AHEARN, DG AF GARGEYA, IB PRUITT, WR MEYER, SA AHEARN, DG TI CANDIDA-HAEMULONII FROM CLINICAL SPECIMENS IN THE USA SO JOURNAL OF MEDICAL AND VETERINARY MYCOLOGY LA English DT Note ID PICHIA AB Classical yeast identification procedures and DNA relatedness studies confirmed the occurrence of Candida haemulonii among clinical specimens in the USA, particularly isolations from the foot. None of the six clinical isolates studied produced identical API 20C profile codes. C1 GEORGIA STATE UNIV,MICROBIAL & BIOCHEM SCI LAB,POB 4010,ATLANTA,GA 30302. CTR DIS CONTROL,CTR INFECT DIS,DIV MYCOT DIS,ATLANTA,GA 30333. NR 18 TC 17 Z9 18 U1 0 U2 0 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0268-1218 J9 J MED VET MYCOL JI J. Med. Vet. Mycol. PY 1991 VL 29 IS 5 BP 335 EP 338 PG 4 WC Mycology SC Mycology GA GH546 UT WOS:A1991GH54600008 PM 1955954 ER PT J AU JONES, JE ARMSTRONG, CW WOOLARD, CD MILLER, GB AF JONES, JE ARMSTRONG, CW WOOLARD, CD MILLER, GB TI FATAL OCCUPATIONAL ELECTRICAL INJURIES IN VIRGINIA SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE LA English DT Article AB Work-related electrical injuries and fatalities in Virginia were reviewed for the period 1977 to 1985. Of 196 workers electrocuted (0.9/100 000/year), 65% (127) died between May and September. Death rates were highest for male workers in utility companies (10.0/100 000), mining (5.9/100 000), and construction industries (3.9/100 000), but these high risk groups accounted for only 50% of the deaths. Most accidental electrocutions resulted from power line contact (53%) and machine or tool usage or repair (22%). Only 1.5% (2/101) of the workers who died within 6 hours of injury and had blood alcohol concentration tested were legally intoxicated. All workers need safety education on active measures to prevent hazardous electrical exposures, not just those at high risk for electrical injury. Every work-related electrical injury represents a sentinel health event-an opportunity for preventive intervention in the workplace. C1 VIRGINIA DEPT HLTH,RICHMOND,VA. CTR DIS CONTROL,DIV FIELD SERV,EPIDEMIOL PROGRAM OFF,ATLANTA,GA 30333. FU PHS HHS [U53 CCU 300818] NR 30 TC 20 Z9 20 U1 0 U2 2 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 1076-2752 J9 J OCCUP ENVIRON MED JI J. Occup. Environ. Med. PD JAN PY 1991 VL 33 IS 1 BP 57 EP 63 DI 10.1097/00043764-199101000-00015 PG 7 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA ET460 UT WOS:A1991ET46000011 PM 1995803 ER PT J AU ROPER, WL AF ROPER, WL TI TEENAGE HEALTH TEACHING MODULES EVALUATION - PREFACE SO JOURNAL OF SCHOOL HEALTH LA English DT Editorial Material RP ROPER, WL (reprint author), CTR DIS CONTROL,1600 CLIFTON RD NE,ATLANTA,GA 30333, USA. NR 0 TC 2 Z9 2 U1 0 U2 0 PU AMER SCHOOL HEALTH ASSOC PI KENT PA PO BOX 708, KENT, OH 44240 SN 0022-4391 J9 J SCHOOL HEALTH JI J. Sch. Health PD JAN PY 1991 VL 61 IS 1 BP 19 EP 19 PG 1 WC Education & Educational Research; Education, Scientific Disciplines; Health Care Sciences & Services; Public, Environmental & Occupational Health SC Education & Educational Research; Health Care Sciences & Services; Public, Environmental & Occupational Health GA EX414 UT WOS:A1991EX41400003 ER PT J AU NELSON, GD CROSS, FS KOLBE, LJ AF NELSON, GD CROSS, FS KOLBE, LJ TI TEENAGE HEALTH TEACHING MODULES EVALUATION - INTRODUCTION SO JOURNAL OF SCHOOL HEALTH LA English DT Editorial Material C1 CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV ADOLESCENT & SCH HLTH,ATLANTA,GA 30333. RP NELSON, GD (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,ATLANTA,GA 30333, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER SCHOOL HEALTH ASSOC PI KENT PA PO BOX 708, KENT, OH 44240 SN 0022-4391 J9 J SCHOOL HEALTH JI J. Sch. Health PD JAN PY 1991 VL 61 IS 1 BP 20 EP 20 PG 1 WC Education & Educational Research; Education, Scientific Disciplines; Health Care Sciences & Services; Public, Environmental & Occupational Health SC Education & Educational Research; Health Care Sciences & Services; Public, Environmental & Occupational Health GA EX414 UT WOS:A1991EX41400004 ER PT J AU ROSS, JG GOLD, RS LAVIN, AT ERRECART, MT NELSON, GD AF ROSS, JG GOLD, RS LAVIN, AT ERRECART, MT NELSON, GD TI DESIGN OF THE TEENAGE HEALTH TEACHING MODULES EVALUATION SO JOURNAL OF SCHOOL HEALTH LA English DT Article ID EDUCATION C1 UNIV MARYLAND,DEPT HLTH EDUC,COLLEGE PK,MD 20742. FULCRUM ASSOCIATES,WAYLAND,MA 01778. MACRO SYST INC,BURLINGTON,VT 05401. CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,ATLANTA,GA 30333. RP ROSS, JG (reprint author), MACRO SYST INC,SCH HLTH,8630 FENTON ST,SILVER SPRING,MD 20910, USA. NR 24 TC 7 Z9 7 U1 0 U2 0 PU AMER SCHOOL HEALTH ASSOC PI KENT PA PO BOX 708, KENT, OH 44240 SN 0022-4391 J9 J SCHOOL HEALTH JI J. Sch. Health PD JAN PY 1991 VL 61 IS 1 BP 21 EP 25 PG 5 WC Education & Educational Research; Education, Scientific Disciplines; Health Care Sciences & Services; Public, Environmental & Occupational Health SC Education & Educational Research; Health Care Sciences & Services; Public, Environmental & Occupational Health GA EX414 UT WOS:A1991EX41400005 PM 2027289 ER PT J AU ERRECART, MT WALBERG, HJ ROSS, JG GOLD, RS FIEDLER, JL KOLBE, LJ AF ERRECART, MT WALBERG, HJ ROSS, JG GOLD, RS FIEDLER, JL KOLBE, LJ TI EFFECTIVENESS OF TEENAGE HEALTH TEACHING MODULES SO JOURNAL OF SCHOOL HEALTH LA English DT Article C1 UNIV ILLINOIS,COLL EDUC,CHICAGO,IL 60680. MACRO SYST INC,SCH HLTH,SILVER SPRING,MD 20910. UNIV MARYLAND,DEPT HLTH EDUC,COLLEGE PK,MD 20742. FREELANCE CONSULTANT,SILVER SPRING,MD 20902. CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV ADOLESCENT & SCH HLTH,ATLANTA,GA 30333. RP ERRECART, MT (reprint author), MACRO SYST INC,26 COLL ST,BURLINGTON,VT 05401, USA. NR 7 TC 33 Z9 33 U1 0 U2 1 PU AMER SCHOOL HEALTH ASSOC PI KENT PA PO BOX 708, KENT, OH 44240 SN 0022-4391 J9 J SCHOOL HEALTH JI J. Sch. Health PD JAN PY 1991 VL 61 IS 1 BP 26 EP 30 PG 5 WC Education & Educational Research; Education, Scientific Disciplines; Health Care Sciences & Services; Public, Environmental & Occupational Health SC Education & Educational Research; Health Care Sciences & Services; Public, Environmental & Occupational Health GA EX414 UT WOS:A1991EX41400006 PM 2027290 ER PT J AU ROSS, JG LUEPKER, RV NELSON, GD SAAVEDRA, P HUBBARD, BM AF ROSS, JG LUEPKER, RV NELSON, GD SAAVEDRA, P HUBBARD, BM TI TEENAGE HEALTH TEACHING MODULES - IMPACT OF TEACHER-TRAINING ON IMPLEMENTATION AND STUDENT OUTCOMES SO JOURNAL OF SCHOOL HEALTH LA English DT Article C1 UNIV MINNESOTA,SCH PUBL HLTH,1-210 MOOS TOWER,SIS DELAWARE ST SE,MINNEAPOLIS,MN 55455. CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,ATLANTA,GA 30333. UNIV CENT ARKANSAS,DEPT HLTH EDUC,CONWAY,AR 72032. RP ROSS, JG (reprint author), MACRO SYST INC,SCH HLTH,8630 FENTON ST,SILVER SPRING,MD 20910, USA. NR 8 TC 49 Z9 50 U1 0 U2 5 PU AMER SCHOOL HEALTH ASSOC PI KENT PA PO BOX 708, KENT, OH 44240 SN 0022-4391 J9 J SCHOOL HEALTH JI J. Sch. Health PD JAN PY 1991 VL 61 IS 1 BP 31 EP 34 PG 4 WC Education & Educational Research; Education, Scientific Disciplines; Health Care Sciences & Services; Public, Environmental & Occupational Health SC Education & Educational Research; Health Care Sciences & Services; Public, Environmental & Occupational Health GA EX414 UT WOS:A1991EX41400007 PM 2027291 ER PT J AU PARCEL, GS ROSS, JG LAVIN, AT PORTNOY, B NELSON, GD WINTERS, F AF PARCEL, GS ROSS, JG LAVIN, AT PORTNOY, B NELSON, GD WINTERS, F TI ENHANCING IMPLEMENTATION OF THE TEENAGE HEALTH TEACHING MODULES SO JOURNAL OF SCHOOL HEALTH LA English DT Article C1 MACRO SYST INC,SCH HLTH,SILVER SPRING,MD 20910. FULCRUM ASSOCIATES,WAYLAND,MA 01778. CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,ATLANTA,GA 30333. MACRO SYST INC,STAT ANAL,SILVER SPRING,MD 20910. RP PARCEL, GS (reprint author), UNIV TEXAS,HLTH SCI CTR,CTR HLTH PROMOT RES & DEV,1200 HERMANN PRESSLER ST,ROOM 902 W,HOUSTON,TX 77030, USA. NR 0 TC 41 Z9 41 U1 1 U2 1 PU AMER SCHOOL HEALTH ASSOC PI KENT PA PO BOX 708, KENT, OH 44240 SN 0022-4391 J9 J SCHOOL HEALTH JI J. Sch. Health PD JAN PY 1991 VL 61 IS 1 BP 35 EP 38 PG 4 WC Education & Educational Research; Education, Scientific Disciplines; Health Care Sciences & Services; Public, Environmental & Occupational Health SC Education & Educational Research; Health Care Sciences & Services; Public, Environmental & Occupational Health GA EX414 UT WOS:A1991EX41400008 PM 2027292 ER PT J AU SERDULA, MK CAIRNS, KA WILLIAMSON, DF BROWN, JE AF SERDULA, MK CAIRNS, KA WILLIAMSON, DF BROWN, JE TI CORRELATES OF BREAST-FEEDING IN A LOW-INCOME POPULATION OF WHITES, BLACKS, AND SOUTHEAST ASIANS SO JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION LA English DT Article ID UNITED-STATES; IMMIGRANTS; CALIFORNIA; PATTERNS; DURATION; HEALTH; WOMEN; MILK AB Infant feeding was examined in 492 children in a population-based survey conducted in a low-income, urban county of St Paul, Minn. Of 41 Southeast Asian infants who were foreign born, 93% (38) had been breast-fed compared with 10% (12) of Southeast Asian infants born in the United States ( n = 116). Among non-Southeast Asian infants, 73% (173) of whites (n = 237), 63% (27) of blacks (n = 43) and 65% (36) of other ethnic groups ( n = 55) had been breast-fed. Among the non-Southeast Asian infants, the initiation of breast-feeding was associated with higher parental education and with being married. Ethnic group, level of poverty, and participation in the Supplemental Food Program for Women, Infants, and Children during pregnancy did not appear to influence the initiation of breast-feeding. The findings indicate a higher incidence of breast-feeding than in previous surveys of low-income black and white women; however, this may reflect the higher education level of the non-Southeast Asian study population. In contrast, the sharp decline in the incidence of breast-feeding among Southeast Asian infants who were born in the United States compared with those who were foreign born indicates the need for public health approaches to strengthen traditional breast-feeding practices. C1 CTR DIS CONTROL,CTR HLTH PROMOT & EDUCAT,DIV NUTR,ATLANTA,GA 30333. UNIV MINNESOTA,SCH PUBL HLTH,DIV HUMAN DEV & NUTR,MINNEAPOLIS,MN 55455. ST PAUL DIV PUBL HLTH,ST PAUL,MN 55101. RP SERDULA, MK (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV NUTR,ATLANTA,GA 30333, USA. NR 16 TC 16 Z9 16 U1 1 U2 3 PU AMER DIETETIC ASSN PI CHICAGO PA 216 W JACKSON BLVD #800, CHICAGO, IL 60606-6995 SN 0002-8223 J9 J AM DIET ASSOC JI J. Am. Diet. Assoc. PD JAN PY 1991 VL 91 IS 1 BP 41 EP 45 PG 5 WC Nutrition & Dietetics SC Nutrition & Dietetics GA ER685 UT WOS:A1991ER68500004 PM 1869758 ER PT J AU MOCARELLI, P NEEDHAM, LL MAROCCHI, A PATTERSON, DG BRAMBILLA, P GERTHOUX, PM MEAZZA, L CARRERI, V AF MOCARELLI, P NEEDHAM, LL MAROCCHI, A PATTERSON, DG BRAMBILLA, P GERTHOUX, PM MEAZZA, L CARRERI, V TI SERUM CONCENTRATIONS OF 2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN AND TEST-RESULTS FROM SELECTED RESIDENTS OF SEVESO, ITALY SO JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH LA English DT Article ID TCDD; WORKERS; DIOXIN; CONTAMINATION; CHLORACNE; CHILDREN AB 2,3,7,8-Tetrachlorodibenzo-p-dioxin levels (TCDD) were measured in serum specimens from Seveso, Italy, residents, who were potentially highly exposed to the 1976 explosion, and in controls. The residents were chosen so as to represent those who did and did not develop chloracne. Levels of TCDD as high as 56,000 parts per trillion (ppt) were found in these serum specimens that were collected in 1976. These TCDD levels are the highest ever reported, and yet almost all clinical laboratory tests on these individuals were normal; any abnormal test result was only transitory in nature. These findings are unique in linking clinical histories to TCDD levels following an acute exposure. C1 UNIV MILAN,INST GEN PATHOL,I-20122 MILAN,ITALY. CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV ENVIRONM HLTH LAB SCI,ATLANTA,GA 30333. HLTH MINIST REG LOMBARDIA,PUBL HYG SERV,MILAN,ITALY. RP MOCARELLI, P (reprint author), UNIV DESIO,HOSP DESIO,DEPT PATHOL,I-20033 DESIO,ITALY. RI Needham, Larry/E-4930-2011 NR 27 TC 91 Z9 93 U1 0 U2 2 PU TAYLOR & FRANCIS PI BRISTOL PA 1900 FROST ROAD, SUITE 101, BRISTOL, PA 19007-1598 SN 0098-4108 J9 J TOXICOL ENV HEALTH JI J. Toxicol. Environ. Health PY 1991 VL 32 IS 4 BP 357 EP 366 PG 10 WC Environmental Sciences; Public, Environmental & Occupational Health; Toxicology SC Environmental Sciences & Ecology; Public, Environmental & Occupational Health; Toxicology GA FH208 UT WOS:A1991FH20800001 PM 1826746 ER PT J AU LINHART, SB BLOM, FS DASCH, GJ ROBERTS, JD ENGEMAN, RM ESPOSITO, JJ SHADDOCK, JH BAER, GM AF LINHART, SB BLOM, FS DASCH, GJ ROBERTS, JD ENGEMAN, RM ESPOSITO, JJ SHADDOCK, JH BAER, GM TI FORMULATION AND EVALUATION OF BAITS FOR ORAL RABIES VACCINATION OF RACCOONS (PROCYON-LOTOR) SO JOURNAL OF WILDLIFE DISEASES LA English DT Article DE BAIT PREFERENCE; CAPTIVITY TRIALS; ORAL DELIVERY; PROCYON-LOTOR; RABIES; RACCOONS; RECOMBINANT; TASTE; VACCINE ID IMMUNIZATION; FOXES AB Captive raccoons were offered a variety of vaccine containers and bait components in a series of three-choice tests. Paraffin wax ampules were the most readily accepted vaccine container. Preferred bait components included corn and shellfish oils, deep fried corn meal batter, and egg, apple and buttermilk flavorings. These results, together with factors including ease of bait formulation, cost, and suitability for field use, were used to develop an experimental delivery system for an oral rabies vaccine. The developed system was composed of a polyurethane sleeve (1.5 x 5.5 cm) dipped in a commercial food batter mix together with corn meal, milk and egg. The sleeve was deep fried in corn oil and a 2.0 ml ampule containing a recombinant rabies vaccine was then inserted into the sleeve bait. These baits were presented to 10 captive raccoons. Nine of the 10 animals developed high levels of rabies virus neutralizing antibodies. Field tests are needed to determine if the delivery system developed also is effective for wild raccoons. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL DIS,ATLANTA,GA 30333. RP LINHART, SB (reprint author), USDA,DENVER WILDLIFE RES CTR,SCI & TECHNOL ANIM & PLANT HLTH INSPECT SERV,POB 25266,DENVER,CO 80225, USA. NR 30 TC 21 Z9 22 U1 0 U2 2 PU WILDLIFE DISEASE ASSN, INC PI LAWRENCE PA 810 EAST 10TH ST, LAWRENCE, KS 66044-8897 SN 0090-3558 J9 J WILDLIFE DIS JI J. Wildl. Dis. PD JAN PY 1991 VL 27 IS 1 BP 21 EP 33 PG 13 WC Veterinary Sciences SC Veterinary Sciences GA EW549 UT WOS:A1991EW54900004 PM 2023324 ER PT J AU ZAKI, SR JUDD, R COFFIELD, LM GREER, P ROLSTON, F EVATT, BL AF ZAKI, SR JUDD, R COFFIELD, LM GREER, P ROLSTON, F EVATT, BL TI HUMAN PAPILLOMAVIRUS INFECTION AND ANAL CARCINOMA - RETROSPECTIVE ANALYSIS BY INSITU HYBRIDIZATION AND THE POLYMERASE CHAIN-REACTION SO LABORATORY INVESTIGATION LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. EMORY UNIV,SCH MED,ATLANTA,GA 30322. NR 0 TC 0 Z9 0 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0023-6837 J9 LAB INVEST JI Lab. Invest. PD JAN PY 1991 VL 64 IS 1 BP A90 EP A90 PG 1 WC Medicine, Research & Experimental; Pathology SC Research & Experimental Medicine; Pathology GA EV366 UT WOS:A1991EV36600548 ER PT J AU TAUXE, RV GRIFFIN, PM OSTROFF, SM WACHSMUTH, IK AF TAUXE, RV GRIFFIN, PM OSTROFF, SM WACHSMUTH, IK TI DIAGNOSING ESCHERICHIA-COLI SO LABORATORY MEDICINE LA English DT Letter RP TAUXE, RV (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 0 TC 2 Z9 2 U1 0 U2 1 PU AMER SOC CLIN PATHOLOGISTS PI CHICAGO PA 2100 W HARRISON ST, CHICAGO, IL 60612 SN 0007-5027 J9 LAB MED JI Lab. Med. PD JAN PY 1991 VL 22 IS 1 BP 55 EP 56 PG 2 WC Medical Laboratory Technology SC Medical Laboratory Technology GA EN462 UT WOS:A1991EN46200015 ER PT J AU COLLINS, MD RODRIGUES, UM PIGOTT, NE FACKLAM, RR AF COLLINS, MD RODRIGUES, UM PIGOTT, NE FACKLAM, RR TI ENTEROCOCCUS-DISPAR SP-NOV A NEW ENTEROCOCCUS SPECIES FROM HUMAN SOURCES SO LETTERS IN APPLIED MICROBIOLOGY LA English DT Article ID 16S RIBOSOMAL-RNA; LACTOCOCCI AB The partial 16S rRNA sequences of two unknown human enterococcal isolates were determined by reverse transcription in an attempt to clarify their taxonomic position. The sequence data indicate that they belong to a hitherto unknown species of Enterococcus, for which the name Enterococcus dispar sp. nov. is proposed. The type strain is NCIMB 13000. C1 CTR DIS CONTROL, ATLANTA, GA 30333 USA. RP COLLINS, MD (reprint author), INST FOOD RES, DEPT MICROBIOL, READING LAB, READING RG2 9AT, ENGLAND. NR 11 TC 37 Z9 38 U1 0 U2 8 PU WILEY-BLACKWELL PI MALDEN PA COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA SN 0266-8254 J9 LETT APPL MICROBIOL JI Lett. Appl. Microbiol. PY 1991 VL 12 IS 3 BP 95 EP 98 DI 10.1111/j.1472-765X.1991.tb00514.x PG 4 WC Biotechnology & Applied Microbiology; Microbiology SC Biotechnology & Applied Microbiology; Microbiology GA FB112 UT WOS:A1991FB11200009 PM 1370024 ER PT J AU HOOPER, WC AF HOOPER, WC TI THE ROLE OF TRANSFORMING GROWTH-FACTOR-BETA IN HEMATOPOIESIS - A REVIEW SO LEUKEMIA RESEARCH LA English DT Review DE TRANSFORMING GROWTH FACTOR-BETA; HEMATOPOIETIC CELLS; CYTOKINES ID NECROSIS FACTOR-ALPHA; CELL-GROWTH; DIFFERENTIATION FACTORS; PROGENITOR CELLS; PROLIFERATION; FACTOR-BETA-1; INDUCTION; RECEPTORS; FAMILY RP HOOPER, WC (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV IMMUNOL ONCOL & HEMATOL,ATLANTA,GA 30333, USA. NR 34 TC 57 Z9 57 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0145-2126 J9 LEUKEMIA RES JI Leuk. Res. PY 1991 VL 15 IS 4 BP 179 EP 184 DI 10.1016/0145-2126(91)90118-D PG 6 WC Oncology; Hematology SC Oncology; Hematology GA FJ132 UT WOS:A1991FJ13200002 PM 2030598 ER PT J AU HOOPER, WC JACKSON, D PRUCKLER, J EVATT, BL AF HOOPER, WC JACKSON, D PRUCKLER, J EVATT, BL TI CELLULAR KINETICS OF TRANSFORMING GROWTH-FACTOR-BETA INDUCED HEMOGLOBIN ACCUMULATION IN THE HEL ERYTHROLEUKEMIA CELL-LINE SO LEUKEMIA RESEARCH LA English DT Article DE TRANSFORMING GROWTH FACTOR-BETA; HEMOGLOBIN; ERYTHROLEUKEMIA ID HUMAN-BONE MARROW; TERMINAL DIFFERENTIATION; K562 CELLS; INDUCTION; INVITRO; BINDING; HEMIN AB Transforming growth factor-beta 1 (TGF-beta-1) can induce hemoglobin accumulation in a clone of the human HEL erythroleukemia cell line. This clone has previously been designated as HEL-T. The effect of TGF-beta-1 was reversible and it had to be continuously present for the maximal number of cells to become positive for hemoglobin. The TGF-beta-1 effect was blocked by phorbol ester and partially blocked by the calmodulin antagonist W-7, but not by dexamethasone. Simultaneous exposure to gamma-interferon, IL-1, IL-6, IL-3 and GM-CSF had no significant effect on TGF-beta induced hemoglobin accumulation. However, when TGF-beta was combined with TNF-alpha, it was observed that there was approximately a 10-15% reduction in benzidine-positive cells. Cell-cycle analysis revealed no significant long-term alterations in any of the compartments. Analysis of the TGF-beta-1 effect on 10 different HEL-T-derived clones revealed that the number of benzidine-positive cells ranged from 12 to 70% after 5 days of continuous exposure. Cell proliferation was similarly differentially affected. Another HEL cell line, designated as W-HEL, did not accumulate hemoglobin in the presence of TGF-beta-1, but did have an increase in alpha-globin RNA expression. RP HOOPER, WC (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV IMMUNOL ONCOL & HEMATOL DIS,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 17 TC 2 Z9 2 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0145-2126 J9 LEUKEMIA RES JI Leuk. Res. PY 1991 VL 15 IS 8 BP 745 EP & DI 10.1016/0145-2126(91)90078-8 PG 0 WC Oncology; Hematology SC Oncology; Hematology GA GF768 UT WOS:A1991GF76800012 PM 1895755 ER PT J AU HOOPER, WC PRUCKLER, J JACKSON, D EVATT, BL AF HOOPER, WC PRUCKLER, J JACKSON, D EVATT, BL TI THE SYNERGISTIC EFFECT OF HEMIN AND TRANSFORMING GROWTH-FACTOR-BETA ON HEMOGLOBIN ACCUMULATION IN HEL ERYTHROLEUKEMIA-CELLS SO LEUKEMIA RESEARCH LA English DT Article DE TRANSFORMING GROWTH FACTOR-BETA; HEMIN; HEMOGLOBIN; ERYTHROLEUKEMIA ID HUMAN-BONE MARROW; TERMINAL DIFFERENTIATION; INDUCTION; GLOBIN; K-562; LINE AB Transforming growth factor-beta (TGF-beta) and hemin can both independently induce hemoglobin accumulation in the human HEL erythroleukemia cell line. The combination of these two agents resulted in a synergistic effect in the production of hemoglobin. On day 1, following exposure to both hemin and TGF-beta, approximately 35% of the cells had accumulated hemoglobin, as evidenced, by benzidine staining. Whereas, when treated alone with either agent, the percentage of benzidine-positive cells was less than 10%. By day 5, approximately 70-80% on the cells treated with the combination were benzidine-positive. Cell surface analysis showed that the combination of TGF-beta and hemin increased the expression of CD34, CD64, glycophorin A, and GPIIb-IIIa(CDW41). Cell proliferation was decreased by the combination. RP HOOPER, WC (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV IMMUNOL ONCOL & HEMATOL DIS,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 19 TC 7 Z9 7 U1 0 U2 0 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0145-2126 J9 LEUKEMIA RES JI Leuk. Res. PY 1991 VL 15 IS 8 BP 753 EP 758 DI 10.1016/0145-2126(91)90079-9 PG 6 WC Oncology; Hematology SC Oncology; Hematology GA GF768 UT WOS:A1991GF76800013 PM 1895756 ER PT J AU TAN, WY AF TAN, WY TI SOME GENERAL STOCHASTIC-MODELS FOR THE SPREAD OF AIDS AND SOME SIMULATION RESULTS SO MATHEMATICAL AND COMPUTER MODELLING LA English DT Article ID HIV INFECTION; TRANSMISSION; EPIDEMIC AB To describe the dynamics of the AIDS epidemic, the purpose of this paper is to develop a stochastic model for the AIDS epidemic in complex situations. To take into account different risk groups, social factors and levels of sexual activities, in this paper we consider l risk populations with each risk population being further classified into n subpopulations. To take into account some important biological aspects of AIDS epidemic, in each population we postulate an L person and divide the infectious persons (I persons) into k stages and the AIDS cases (A persons) into m stages. Given these specifications, the probability generating function (PGF) of the numbers of L persons, infectious persons and AIDS cases is then derived under some general conditions. By using this PGF, it is shown that the expected values, the variances and the covariances of the latent persons, infective persons and AIDS cases satisfy some ordinary differential equations. These equations have been solved numerically to assess effects of various factors on the AIDS epidemic. C1 CTR DIS CONTROL,DIV HIV AIDS,ATLANTA,GA 30333. RP TAN, WY (reprint author), MEMPHIS STATE UNIV,DEPT MATH SCI,MEMPHIS,TN 38152, USA. NR 13 TC 6 Z9 6 U1 0 U2 1 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0895-7177 J9 MATH COMPUT MODEL JI Math. Comput. Model. PY 1991 VL 15 IS 2 BP 19 EP 39 DI 10.1016/0895-7177(91)90113-L PG 21 WC Computer Science, Interdisciplinary Applications; Computer Science, Software Engineering; Mathematics, Applied SC Computer Science; Mathematics GA FC759 UT WOS:A1991FC75900003 ER PT J AU JACOBS, WR KALPANA, GV CIRILLO, JD PASCOPELLA, L SNAPPER, SB UDANI, RA JONES, W BARLETTA, RG BLOOM, BR AF JACOBS, WR KALPANA, GV CIRILLO, JD PASCOPELLA, L SNAPPER, SB UDANI, RA JONES, W BARLETTA, RG BLOOM, BR TI GENETIC SYSTEMS FOR MYCOBACTERIA SO METHODS IN ENZYMOLOGY LA English DT Review ID FOREIGN DNA; TRANSFORMATION; EXPRESSION C1 UNIV NEBRASKA, DEPT VET SCI, LINCOLN, NE 68583 USA. CTR DIS CONTROL, MYCOBACTERIOL LAB, ATLANTA, GA 30333 USA. RP YESHIVA UNIV ALBERT EINSTEIN COLL MED, HOWARD HUGHES MED INST, DEPT MICROBIOL & IMMUNOL, BRONX, NY 10461 USA. NR 17 TC 6 Z9 6 U1 0 U2 0 PU ACADEMIC PRESS INC ELSEVIER SCIENCE PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA SN 0076-6879 J9 METHOD ENZYMOL JI Methods Enzymol. PY 1991 VL 204 BP 537 EP 555 PG 19 WC Biochemical Research Methods; Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA GN469 UT WOS:A1991GN46900025 ER PT J AU HARA, I SATO, N MATSUURA, A CHO, JM QI, WM TORIGOE, T SHINNICK, TM KAMIDONO, S KIKUCHI, K AF HARA, I SATO, N MATSUURA, A CHO, JM QI, WM TORIGOE, T SHINNICK, TM KAMIDONO, S KIKUCHI, K TI DEVELOPMENT OF MONOCLONAL-ANTIBODIES REACTING AGAINST MYCOBACTERIAL 65 KDA HEAT-SHOCK PROTEIN BY USING RECOMBINANT TRUNCATED PRODUCTS SO MICROBIOLOGY AND IMMUNOLOGY LA English DT Article ID CELL-SURFACE ANTIGEN; STRESS PROTEINS; GAMMA-DELTA; 65-KILODALTON ANTIGEN; LYMPHOCYTES-T; TUBERCULOSIS; ARTHRITIS; IDENTIFICATION; AUTOIMMUNITY; RECOGNITION AB A mycobacterial 65 kDa molecule is a member of the GroEL heat shock protein family. We developed mAbs reacting against recombinant 65 kDa protein by using a gene (pTB12) which encodes this protein. Three mAbs (B20, B97 and B167) reacted selectively with 65 kDa proteins of Mycobacterium tuberculosis, BCG and Mycobacterium leprae, although B20 and B167 may weakly react with a 15 kDa molecule of mammalian cells. One (B108) was obviously cross-reactive between mycobacterial 65 kDa and the mammalian intracytoplasmic protein. We also developed deletion mutants of pTB12. The localization of these mAb-defined epitopes was determined by using truncated proteins of the Mycobacterium tuberculosis 65 kDa molecule produced in E. coli. Immunohistochemical analysis showed that B20, B97 and B167 mAbs could detect this antigen in experimental granulomas induced by injection of BCG in the subcutaneous tissue of rats. These mAbs should be useful for analyzing the immunobiologic roles of mycobacterial 65 kDa molecules. C1 CTR DIS CONTROL,ATLANTA,GA 30333. SAPPORO MED COLL,DEPT PATHOL,SAPPORO,HOKKAIDO 060,JAPAN. RP HARA, I (reprint author), KOBE UNIV,SCH MED,DEPT UROL,KOBE 650,JAPAN. NR 29 TC 10 Z9 10 U1 0 U2 2 PU CENTER ACADEMIC PUBL JAPAN PI TOKYO PA 4-16 YAYOI 2-CHOME, BUNKYO-KU, TOKYO 113, JAPAN SN 0385-5600 J9 MICROBIOL IMMUNOL JI Microbiol. Immunol. PY 1991 VL 35 IS 11 BP 995 EP 1007 PG 13 WC Immunology; Microbiology SC Immunology; Microbiology GA GW051 UT WOS:A1991GW05100008 PM 1685553 ER PT J AU ESCOBEDO, LG LEE, NC PETERSON, HB WINGO, PA AF ESCOBEDO, LG LEE, NC PETERSON, HB WINGO, PA TI INFERTILITY-ASSOCIATED ENDOMETRIAL CANCER RISK MAY BE LIMITED TO SPECIFIC SUBGROUPS OF INFERTILE WOMEN SO OBSTETRICS AND GYNECOLOGY LA English DT Article ID ESTROGENS; ADENOCARCINOMA; EPIDEMIOLOGY AB Data from previous studies suggest that infertility is a risk factor for endometrial cancer. We used data from the Cancer and Steroid Hormone Study to further characterize this relationship. The subject group comprised 399 women ages 20-54 with newly diagnosed epithelial endometrial cancer ascertained through six cancer registries. The control group comprised 3040 women in the same age range selected by random-digit telephone dialing from the same geographic areas where cancer patients resided. Compared with women who reported no fertility problem, women with physician-diagnosed infertility who had reported at least 2 years of infertility had an odds ratio for endometrial cancer, adjusted for age, of 1.7 (95% confidence interval 1.1-2.6). Women who reported infertility resulting from ovarian factors had an adjusted odds ratio of 4.2 (95% confidence interval 1.7-10.4). These results suggest that factors such as anovulation may explain much of the increased risk of endometrial cancer found among subgroups of infertile women. RP ESCOBEDO, LG (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV REPROD HLTH,ATLANTA,GA 30333, USA. FU NICHD NIH HHS [3-Y01-HD-8-1037] NR 25 TC 59 Z9 59 U1 0 U2 0 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0029-7844 J9 OBSTET GYNECOL JI Obstet. Gynecol. PD JAN PY 1991 VL 77 IS 1 BP 124 EP 128 PG 5 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA EP415 UT WOS:A1991EP41500025 PM 1984211 ER PT J AU HURWITZ, ES GUNN, WJ PINSKY, PF SCHONBERGER, LB AF HURWITZ, ES GUNN, WJ PINSKY, PF SCHONBERGER, LB TI RISK OF RESPIRATORY ILLNESS ASSOCIATED WITH DAY-CARE ATTENDANCE - A NATIONWIDE STUDY SO PEDIATRICS LA English DT Article DE DAY-CARE FACILITIES; RESPIRATORY ILLNESS AB The risk of respiratory and other illnesses in children (age groups: 6 weeks through 17 month, 18 through 35 months, and 36 through 59 months) in various types of day-care facilities was studied. Children considered exposed to day care were those who were enrolled in day care with at least one unrelated child for at least 10 hours per week in each of the 4 weeks before the interview; unexposed children were no enrolled in any regular child care with unrelated children and did no have siblings younger than 5 years of age receiving regular care with unrelated children. Although an increase risk of respiratory illness was associated with attending day care for children in all three age groups, this risk was statistically significant only for children 6 weeks through 17 months of age (odds ratio = 1.6; 95% confidence interval = 1.1 to 2.4) and children 18 through 35 months of age who had no older siblings (odds ratio = 3.4; 95% confidence interval = 2.0 to 6.0). In contrast, day-care attendance was not associated with an increased risk of respiratory illness in children 18 through 35 months of age with older siblings (odds ratio = 1.0). For children aged 6 weeks through 17 months, the exposure to older siblings was associated with an increased risk of respiratory illness; however, for children aged 36 through 59 months, older siblings were protective against respiratory illness. In addition, for the children in each age group currently in day care, increased duration of past exposure to day care was associated with a decreased risk of respiratory illness. It is estimated that during the period of the study approximately 10% of respiratory illnesses in the United States in children younger than 5 years of age were attributable to day-care attendance. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,MAIL STOP A-32,ATLANTA,GA 30333. NR 12 TC 121 Z9 121 U1 0 U2 6 PU AMER ACAD PEDIATRICS PI ELK GROVE VILLAGE PA 141 NORTH-WEST POINT BLVD, ELK GROVE VILLAGE, IL 60007-1098 SN 0031-4005 J9 PEDIATRICS JI Pediatrics PD JAN PY 1991 VL 87 IS 1 BP 62 EP 69 PG 8 WC Pediatrics SC Pediatrics GA EQ978 UT WOS:A1991EQ97800010 PM 1984620 ER PT J AU FARIZO, KM STEHRGREEN, PA SIMPSON, DM MARKOWITZ, LE AF FARIZO, KM STEHRGREEN, PA SIMPSON, DM MARKOWITZ, LE TI PEDIATRIC EMERGENCY ROOM VISITS - A RISK FACTOR FOR ACQUIRING MEASLES SO PEDIATRICS LA English DT Article DE MEASLES; EMERGENCY ROOMS; MEASLES TRANSMISSION; MEASLES VACCINE; MEASLES OUTBREAKS ID AIRBORNE TRANSMISSION; MEDICAL SETTINGS; OUTBREAK; OFFICE AB In recent years, measles outbreaks have occurred among unimmunized children in inner cities in the United States. From May 1988 through June 1989, 1214 measles cases were reported in Los Angeles, and from October 1988 through June 1989, 1730 cases were reported in Houston. More than half of cases were in children younger than 5 years of age, most of whom were unvaccinated. Of cases of measles in preschool-aged children, nearly one fourth in Lost Angeles and more than one third in Houston were reported by one inner-city emergency room. To evaluate whether emergency room visits were a risk factor for acquiring measles, in Los Angeles, 35 measles patients and 109 control patients will illnesses other than measles, and in Houston, 49 measles patients and 128 control patients, who visited these emergency rooms, were enrolled in case-control studies. Control patients were matched to case patients for ethnicity, age, and week of visit. Records were reviews to determine whether case patients had visited the emergency room during the period of potential measles exposure, which was defined as 10 to 18 days before rash onset, and whether control patients had visited 10 to 18 days before their enrollment visit. In Los Angeles, 23% of case patients and 5% of control patients (odds ratio = 5.2, 95% confidence interval = 1.7, 15.9; P < .01), and in Houston, 41% of case patients and 6% of control patients (odds ratio = 8.4, 95% confidence interval = 3.3, 21,2; P < .01), visited the emergency room during these periods. These data suggest that measles transmission in pediatric emergency rooms played a prominent role in perpetuating these outbreaks. measles transmission in emergency rooms can be reduced by triage and isolation of suspected cases and by vaccination of eligible patients. Vaccination in emergency rooms provides postexposure prophylaxis and may increase vaccination coverage in the community. RP FARIZO, KM (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,DIV IMMUNIZATION,ATLANTA,GA 30333, USA. NR 30 TC 33 Z9 35 U1 0 U2 3 PU AMER ACAD PEDIATRICS PI ELK GROVE VILLAGE PA 141 NORTH-WEST POINT BLVD, ELK GROVE VILLAGE, IL 60007-1098 SN 0031-4005 J9 PEDIATRICS JI Pediatrics PD JAN PY 1991 VL 87 IS 1 BP 74 EP 79 PG 6 WC Pediatrics SC Pediatrics GA EQ978 UT WOS:A1991EQ97800012 PM 1984623 ER PT J AU MAY, DS STROUP, NE AF MAY, DS STROUP, NE TI THE INCIDENCE OF SARCOMAS OF THE BREAST AMONG WOMEN IN THE UNITED-STATES, 1973-1986 SO PLASTIC AND RECONSTRUCTIVE SURGERY LA English DT Letter ID CANCER RP MAY, DS (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,OFF SURVEILLANCE & ANAL,ATLANTA,GA 30333, USA. NR 10 TC 47 Z9 48 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0032-1052 J9 PLAST RECONSTR SURG JI Plast. Reconstr. Surg. PD JAN PY 1991 VL 87 IS 1 BP 193 EP 194 DI 10.1097/00006534-199101000-00045 PG 2 WC Surgery SC Surgery GA EQ143 UT WOS:A1991EQ14300035 PM 1984266 ER PT J AU VARTIAINEN, E DU, DJ MARKS, JS KORHONEN, H GENG, GY GUO, ZY KOPLAN, JP PIETINEN, P WE, GL WILLIAMSON, D NISSINEN, A AF VARTIAINEN, E DU, DJ MARKS, JS KORHONEN, H GENG, GY GUO, ZY KOPLAN, JP PIETINEN, P WE, GL WILLIAMSON, D NISSINEN, A TI MORTALITY, CARDIOVASCULAR RISK-FACTORS, AND DIET IN CHINA, FINLAND, AND THE UNITED-STATES SO PUBLIC HEALTH REPORTS LA English DT Article AB Mortality, cardiovascular risk factors, and diet were compared in Tianjin province, People's Republic of China; in North Karelia Province, Finland; and in the United States as a whole. People in Tianjin received 7 percent of their energy intake from saturated fats, whereas people in the United States received 13 percent and those in North Karelia received 20. The mean blood cholesterol levels for men were 158 milligrams per deciliter (mg per dl) for Tianjin, 216 mg per dl for the United States, and 241 mg per dl for North Karelia. The smoking prevalence among men was highest in Tianjin (66 percent), followed by the United States (42 percent) and Finland (36 percent). The differences among mortality rates for the three locales were less pronounced among women than among men. Age-standardized total mortality for women was highest for Tianjin and lowest in North Karelia. The reverse was true for men. Age-standardized total mortality for men was lowest in Tianjin and highest in North Karelia. Age-standardized ischemic heart disease mortality for men was lowest in Tianjin (99 per 100,000) and highest in North Karelia (730 per 100,000). For women, the corresponding figures were 83 per 100,000 in Tianjin and 164 per 100,000 in North Karelia. Although salt intake was higher in Tianjin than in North Karelia, the blood pressure was on average lower in persons from Tianjin than in those from North Karelia. The stroke mortality rate in Tianjin, however, was much higher than in either Finland or the United States. The strong discrepancy in stroke mortality relative to prevalence of hypertension and salt intake raises the issue of the etiology of stroke in Tianjin. Recently it has been reported that hemorrhagic stroke may be more common among people whose blood cholesterol level is very low and blood pressure level high. This joint condition may be relatively common in Tianjin and calls for longitudinal and case-control studies to clarify the relationships among these factors in Tianjin. C1 NATL PUBL HLTH INST,SF-00280 HELSINKI 28,FINLAND. CTR NONCOMMUNICABLE DIS RES PREVENT & CONTROL,OFF COORDINAT,TIANJIN,PEOPLES R CHINA. UNIV KUOPIO,KUOPIO,FINLAND. CTR DIS CONTROL,ATLANTA,GA 30333. NR 19 TC 23 Z9 23 U1 0 U2 1 PU US GOVERNMENT PRINTING OFFICE PI WASHINGTON PA SUPT OF DOCUMENTS, WASHINGTON, DC 20402-9325 SN 0033-3549 J9 PUBLIC HEALTH REP JI Public Health Rep. PD JAN-FEB PY 1991 VL 106 IS 1 BP 41 EP 46 PG 6 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EX644 UT WOS:A1991EX64400010 PM 1899938 ER PT J AU EVENSON, DP JOST, LK BAER, RK TURNER, TW SCHRADER, SM AF EVENSON, DP JOST, LK BAER, RK TURNER, TW SCHRADER, SM TI INDIVIDUALITY OF DNA DENATURATION PATTERNS IN HUMAN SPERM AS MEASURED BY THE SPERM CHROMATIN STRUCTURE ASSAY SO REPRODUCTIVE TOXICOLOGY LA English DT Article DE HUMAN SEMEN QUALITY; LONGITUDINAL STUDY; FLOW CYTOMETRY; SPERM CHROMATIN STRUCTURE ASSAY; SCSA; DNA DENATURATION; ACRIDINE ORANGE; INTRACLASS CORRELATION ID GENE-TOX PROGRAM; REPRODUCTIVE RISK; GONADAL-FUNCTION; FLOW-CYTOMETRY; SEMEN QUALITY; TESTS; CHEMOTHERAPY; FERTILITY; WORKERS AB Eight monthly semen samples from 45 men not known to be exposed to industrial toxicants were measured by the flow cytometric sperm chromatin structure assay (SCSA). This assay determines susceptibility of sperm DNA to in situ, acid-induced denaturation and is quantitated by the metachromatic shift of acridine orange fluorescence from green (native DNA) to red (denatured DNA). The observed green versus red fluorescence scattergram (cytogram) patterns were generally unique between donors and homogeneous within a donor over time. Within a donor, the cytogram patterns were the same whether intact sperm cells or detached nuclei were measured. For some individuals the cytogram patterns differed for some months and then returned to the original pattern. Intraclass correlations for mean and standard deviation of alpha t [alpha-t = red/(red + green) fluorescence] were higher (.67 to .90) than any classically measured semen variables, suggesting that SCSA results within an individual were more consistent than other measures. Furthermore, average within-donor CV of alpha-t parameters expressed as a percent of any given individual's means was around 10%, which is significantly lower than those derived from common semen measures. The SCSA is an objective, technically sound, biologically stable, sensitive, and feasible measure of semen quality. C1 NIOSH,DIV BIOMED & BEHAV SCI,CINCINNATI,OH 45226. RP EVENSON, DP (reprint author), S DAKOTA STATE UNIV,OLSON BIOCHEM LABS,ANIM SCI COMPLEX 136,BROOKINGS,SD 57007, USA. RI Schrader, Steven/E-8120-2011 NR 30 TC 189 Z9 198 U1 0 U2 6 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0890-6238 J9 REPROD TOXICOL JI Reprod. Toxicol. PY 1991 VL 5 IS 2 BP 115 EP 125 DI 10.1016/0890-6238(91)90039-I PG 11 WC Reproductive Biology; Toxicology SC Reproductive Biology; Toxicology GA FB805 UT WOS:A1991FB80500004 PM 1807542 ER PT J AU HOLMES, GP AF HOLMES, GP TI DEFINING THE CHRONIC FATIGUE SYNDROME SO REVIEWS OF INFECTIOUS DISEASES LA English DT Article; Proceedings Paper CT CONF ON CONSIDERATIONS IN THE DESIGN OF STUDIES OF CHRONIC FATIGUE SYNDROME CY SEP 15-16, 1988 CL PITTSBURGH, PA SP UNIV PITTSBURGH, NIAID ID EPSTEIN-BARR VIRUS; INFECTION AB The recently published working definition of the chronic fatigue syndrome (CFS) is a necessary first step toward a consistent effort to research this controversial illness. Before this definition was developed, cases often were defined vaguely, according to the perceptions and biases of the individual researchers, so that the results of some studies were unclear. However, few specific diagnostic parameters for CFS exist, and the new definition may not delineate a single clinicopathologic entity. Future efforts at researching this illness should be aimed at identifying parameters that differentiate CFS from psychiatric conditions such as major depression and from other defined chronic diseases. Because CFS may be the result of multiple disease processes, the separate study of well-defined subgroups of patients with CFS is appropriate. Such subgroups of patients are probably more likely to have common pathogenetic features than are patients with CFS as a whole group. C1 CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL DIS,EPIDEMIOL OFF,ATLANTA,GA 30333. NR 12 TC 24 Z9 24 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0162-0886 J9 REV INFECT DIS PD JAN-FEB PY 1991 VL 13 SU 1 BP S53 EP S55 PG 3 WC Immunology; Microbiology SC Immunology; Microbiology GA EV311 UT WOS:A1991EV31100010 PM 2020802 ER PT J AU BERDAL, BP FIELDS, PI MELBYE, H AF BERDAL, BP FIELDS, PI MELBYE, H TI CHLAMYDIA PNEUMONIAE RESPIRATORY-TRACT INFECTION - THE INTERPRETATION OF HIGH TITERS IN THE COMPLEMENT-FIXATION TEST SO SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES LA English DT Article ID STRAIN; TWAR AB Sera from 5 acute respiratory disease patients from Northern Norway presenting with high chlamydia complement fixation (CF) titres, were analyzed for Chlamydia pneumoniae-specific IgG and IgM in a micro-immunofluorescence (micro-IF) test that included antigens from the prototype strain TW 183, and a Norwegian isolate, FML 10. The patients were confirmed to have had C. pneumoniae infection based on serologic findings. This establishes the clinical significance of early CF results in this geographical area. However, different micro-IF titres against the 2 C. pneumoniae isolates tested suggest antigenic variability among the species. C1 UNIV TROMSO,INST COMMUNITY MED,N-9001 TROMSO,NORWAY. CTR DIS CONTROL,CTR INFECT DIS,ATLANTA,GA 30333. NR 7 TC 8 Z9 8 U1 0 U2 0 PU SCANDINAVIAN UNIVERSITY PRESS PI OSLO PA PO BOX 2959 TOYEN, JOURNAL DIVISION CUSTOMER SERVICE, N-0608 OSLO, NORWAY SN 0036-5548 J9 SCAND J INFECT DIS JI Scand. J. Infect. Dis. PY 1991 VL 23 IS 3 BP 305 EP 307 DI 10.3109/00365549109024315 PG 3 WC Infectious Diseases SC Infectious Diseases GA FU084 UT WOS:A1991FU08400006 PM 1882196 ER PT J AU ARAL, SO SOSKOLINE, V JOESOEF, RM OREILLY, KR AF ARAL, SO SOSKOLINE, V JOESOEF, RM OREILLY, KR TI SEX PARTNER RECRUITMENT AS RISK FACTOR FOR STD - CLUSTERING OF RISKY MODES SO SEXUALLY TRANSMITTED DISEASES LA English DT Article ID FAMILY-PLANNING CLINICS; HEPATITIS-B; CERVICAL-CANCER; WOMEN; TRANSMISSION; INFECTION; DYSPLASIA; BEHAVIOR AB Nine hundred and fourteen heterosexual persons who requested care at STD clinics in South Carolina responded to self-administered questions on STD history, socio-demographic characteristics, number of sexual partners, and sexual partner choice. These data and the current STD diagnosis were analysed using multivariate techniques. Sexual behaviors of men and women were different. Men reported greater number of partners and less discriminating sex partner recruitment patterns. Age, rural/urban residence, race, and number of sex partners were independent predictors of gonorrhea infection among men. Among women, age rural/urban residence, and not knowing the most recent sex partner very well emerged as independent predictors of infection. RP ARAL, SO (reprint author), CTR DIS CONTROL,DIV SEXUALLY TRANSMITTED DIS HIV PREVENT,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 19 TC 39 Z9 39 U1 0 U2 2 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0148-5717 J9 SEX TRANSM DIS JI Sex. Transm. Dis. PD JAN-MAR PY 1991 VL 18 IS 1 BP 10 EP 17 DI 10.1097/00007435-199101000-00003 PG 8 WC Infectious Diseases SC Infectious Diseases GA EZ356 UT WOS:A1991EZ35600003 PM 2028364 ER PT J AU ZENKER, P AF ZENKER, P TI NEW CASE DEFINITION FOR CONGENITAL-SYPHILIS REPORTING SO SEXUALLY TRANSMITTED DISEASES LA English DT Article RP ZENKER, P (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,TECH INFORMAT SERV,MALL STOP E-06,ATLANTA,GA 30333, USA. NR 6 TC 18 Z9 18 U1 0 U2 1 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0148-5717 J9 SEX TRANSM DIS JI Sex. Transm. Dis. PD JAN-MAR PY 1991 VL 18 IS 1 BP 44 EP 45 DI 10.1097/00007435-199101000-00010 PG 2 WC Infectious Diseases SC Infectious Diseases GA EZ356 UT WOS:A1991EZ35600010 PM 1851334 ER PT J AU IRWIN, K BERTRAND, J MIBANDUMBA, N MBUYI, K MUREMERI, C MUKOKA, M MUNKOLENKOLE, K NZILAMBI, N BOSENGE, N RYDER, R PETERSON, H LEE, NC WINGO, P OREILLY, K RUFO, K AF IRWIN, K BERTRAND, J MIBANDUMBA, N MBUYI, K MUREMERI, C MUKOKA, M MUNKOLENKOLE, K NZILAMBI, N BOSENGE, N RYDER, R PETERSON, H LEE, NC WINGO, P OREILLY, K RUFO, K TI KNOWLEDGE, ATTITUDES AND BELIEFS ABOUT HIV-INFECTION AND AIDS AMONG HEALTHY FACTORY-WORKERS AND THEIR WIVES, KINSHASA, ZAIRE SO SOCIAL SCIENCE & MEDICINE LA English DT Article DE AIDS; HEALTH EDUCATION; COUNSELING; FOCUS GROUP RESEARCH ID HUMAN IMMUNODEFICIENCY VIRUS; TRANSMISSION; CONDOMS; AFRICA C1 PROJET NAISSANCES DESIRABLES,KINSHASA,ZAIRE. PROJET SIDA,KINSHASA,ZAIRE. BUR CENT COMITE LUTTE CONTRE SIDA,KINSHASA,ZAIRE. RP IRWIN, K (reprint author), CTR DIS CONTROL,DIV HIV AIDS,MAILSTOP E45,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 40 TC 28 Z9 28 U1 1 U2 2 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0277-9536 J9 SOC SCI MED JI Soc. Sci. Med. PY 1991 VL 32 IS 8 BP 917 EP 930 DI 10.1016/0277-9536(91)90247-A PG 14 WC Public, Environmental & Occupational Health; Social Sciences, Biomedical SC Public, Environmental & Occupational Health; Biomedical Social Sciences GA FD414 UT WOS:A1991FD41400007 PM 2031208 ER PT J AU RICHARDS, F KLEIN, RE GONZALESPERALTA, C FLORES, RZ FLORES, GZ RAMIREZ, JC AF RICHARDS, F KLEIN, RE GONZALESPERALTA, C FLORES, RZ FLORES, GZ RAMIREZ, JC TI KNOWLEDGE, ATTITUDES AND PERCEPTIONS (KAP) OF ONCHOCERCIASIS - A SURVEY AMONG RESIDENTS IN AN ENDEMIC AREA IN GUATEMALA TARGETED FOR MASS CHEMOTHERAPY WITH IVERMECTIN SO SOCIAL SCIENCE & MEDICINE LA English DT Article DE ATTITUDES; THERAPY; ONCHOCERCIASIS; IVERMECTIN ID DIETHYLCARBAMAZINE C1 UNIV ARIZONA,COLL AGR,DEPT ENTOMOL,TUCSON,AZ 85721. MINISTERIO SALUD PUBL & ASISTENCIA SOCIAL GUATEMALA,DEPT ENFERMEDAD ROBLES ONCOCERCOSIS,GUATEMALA CITY,GUATEMALA. UNIV VALLE,CTR INVESTIGACIONES & ENFERMEDADES TROPICALES,GUATEMALA CITY,GUATEMALA. RP RICHARDS, F (reprint author), US PHS,CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,MED ENTOMOL RES & TRAINING UNIT,ATLANTA,GA 30333, USA. NR 28 TC 17 Z9 17 U1 0 U2 1 PU PERGAMON-ELSEVIER SCIENCE LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB SN 0277-9536 J9 SOC SCI MED JI Soc. Sci. Med. PY 1991 VL 32 IS 11 BP 1275 EP 1281 DI 10.1016/0277-9536(91)90043-C PG 7 WC Public, Environmental & Occupational Health; Social Sciences, Biomedical SC Public, Environmental & Occupational Health; Biomedical Social Sciences GA FL672 UT WOS:A1991FL67200009 PM 2068610 ER PT J AU LEVINE, JF APPERSON, CS SPIEGEL, RA NICHOLSON, WL STAES, CJ AF LEVINE, JF APPERSON, CS SPIEGEL, RA NICHOLSON, WL STAES, CJ TI INDIGENOUS CASES OF LYME-DISEASE DIAGNOSED IN NORTH-CAROLINA SO SOUTHERN MEDICAL JOURNAL LA English DT Article ID BORRELIA-BURGDORFERI; AMBLYOMMA-AMERICANUM; ABNORMALITIES; TICKS AB Between January 1984 and December 1989, 102 indigenous cases of Lyme disease were reported in North Carolina. Lyme disease was reported in each of the three major geographic regions of the state: mountain, piedmont, and coastal plain. One or more diagnoses were made in 42 of 100 counties. Patients ranged in age from 5 months to 78 years (median, 27 years); 58 patients (57%) reported a history of tick exposure within 1 month of the onset of symptoms. Erythema migrans was reported by 93 patients (91%). Arthritis (30%), neurologic symptoms (10%), and cardiac abnormalities (7%) were observed. Thirty of the 102 cases were confirmed serologically by indirect fluorescence microscopy or enzyme-linked immunosorbent assay. C1 N CAROLINA STATE UNIV,COLL AGR & LIFE SCI,DEPT ENTOMOL,RALEIGH,NC 27695. CTR DIS CONTROL,DIV FIELD SERV,EPIDEMIOL PROGRAM OFF,ATLANTA,GA 30333. N CAROLINA DEPT ENVIRONM HLTH & NAT RESOURCES,RALEIGH,NC. RP LEVINE, JF (reprint author), N CAROLINA STATE UNIV,COLL VET MED,DEPT MICROBIOL PATHOL & PARASITOL,4700 HILLSBOROUGH ST,RALEIGH,NC 27606, USA. NR 22 TC 8 Z9 8 U1 0 U2 3 PU SOUTHERN MEDICAL ASSN PI BIRMINGHAM PA 35 LAKESHORE DR PO BOX 190088, BIRMINGHAM, AL 35219 SN 0038-4348 J9 SOUTHERN MED J JI South.Med.J. PD JAN PY 1991 VL 84 IS 1 BP 27 EP 31 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA ET884 UT WOS:A1991ET88400008 PM 1986423 ER PT J AU LYNCH, DW SCHULER, RL HOOD, RD DAVIS, DG AF LYNCH, DW SCHULER, RL HOOD, RD DAVIS, DG TI EVALUATION OF DROSOPHILA FOR SCREENING DEVELOPMENTAL TOXICANTS - TEST-RESULTS WITH 18 CHEMICALS AND PRESENTATION OF A NEW DROSOPHILA BIOASSAY SO TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS LA English DT Article DE DEVELOPMENTAL TOXICITY SCREENING ASSAY; DROSOPHILA-BIOASSAY; FRUIT FLY; MORPHOLOGICAL DEFECTS; NONMAMMALIAN SCREEN ID ALCOHOL-DEHYDROGENASE; INVITRO SYSTEMS; MELANOGASTER; TERATOGENICITY; TOXICITY AB The objective of this study was to generate a comprehensive data set of chemically induced malformations in Drosophila using a detailed morphological examination of the entire fly (phase one). These data were analyzed, in blind, with the goal of developing a standardized set of criteria which could be used in a new, rapid, and economical Drosophila bioassay useful in the preliminary screening for potential developmental toxicants. After 32 chemicals were tested, formalized criteria were developed to form the basis of a new Drosophila bioassay. These criteria were then applied to the data from the same 32 chemicals (phase two). The data from only 18 of these chemicals met all requirements for evaluation, e.g., statistical significance, minimum fly numbers, sufficient challenge concentration administered, etc. In the new bioassay, rather than the detailed and time-consuming examination of the entire fly for a multitude of morphological defects, only two specific anatomical sites are examined. These sites are the humeral bristle and the wing blade, with focus placed on two structural defects-a bent bristle and a notch in the wing. These defects were the only two external malformations among the multitude of defects observed in flies treated in the first phase with the 32 chemicals which demonstrated the following characteristics: 1) A consistent concentration-response in flies treated with a variety of developmental toxicants; 2) a lack of response with most presumptive non-developmental toxicants; and 3) consistently low-background incidences in control flies. In both phases, developing Drosophila were exposed to the test agents from the egg through three larval stages by incorporating a range of concentrations of each chemical into the culture medium. Emerging adults were examined for an array of defects as part of a detailed morphological examination in the first phase, including bent bristles and wing notches. In the second phase, only bent bristle and wing notch data were evaluated. The incidences of bent humeral bristles and wing notches from flies exposed to each of the 18 chemicals were compared with those of concurrent controls. Of the 18 chemicals that could be evaluated using the new bioassay, 13 were known developmental toxicants while the remaining 5 were presumptive negative agents. Ten of the 13 mammalian developmental toxicants were correctly identified with this test (false negative rate of 23%). Four of five apparent non-developmental toxicants were correctly identified for a false positive rate of 20%. The sensitivity of the bioassay was 77% (10 of 13 known developmental toxicants accurately detected); the specificity was 80% (4 of 5 negative compounds accurately detected); and the overall accuracy was 78% (14 of 18 chemicals accurately detected). We believe this formalized Drosophila bioassay is an improved version of previous screening tests using intact Drosophila, and that this bioassay shows promise for the screening of chemicals for their potential to induce developmental toxicity. C1 UNIV ALABAMA,DEPT BIOL,TUSCALOOSA,AL 35401. RP LYNCH, DW (reprint author), NIOSH,DIV BIOMED & BEHAV SCI,EXPTL TOXICOL BRANCH,ROBERT A TAFT LABS,CINCINNATI,OH 45226, USA. NR 19 TC 8 Z9 8 U1 0 U2 1 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0270-3211 J9 TERATOGEN CARCIN MUT JI Teratogenesis Carcinog. Mutagen. PY 1991 VL 11 IS 3 BP 147 EP 173 DI 10.1002/tcm.1770110304 PG 27 WC Oncology; Genetics & Heredity; Toxicology SC Oncology; Genetics & Heredity; Toxicology GA GK090 UT WOS:A1991GK09000003 PM 1686822 ER PT J AU ERICKSON, JD AF ERICKSON, JD TI RISK-FACTORS FOR BIRTH-DEFECTS - DATA FROM THE ATLANTA BIRTH-DEFECTS CASE-CONTROL STUDY SO TERATOLOGY LA English DT Article AB The Atlanta Birth Defects Case-Control Study data comprises information obtained from interviews with parents of 4,900 babies born with major birth defects and with the parents of 3,000 babies born without defects. The source of cases is the Centers for Disease Control's Metropolitan Atlanta Congenital Defects Program; the case-control study is population-based. Birth defects are classified into 92 groups and cross-tabulated by 105 exposure/risk factor variables; data from selected cross-tabulations are presented. The associations of each of the 105 exposure variables with all types of defects combined are presented, as are the associations of each of the 92 defect groups with the specific exposure variable, maternal diabetes. These data can be used to evaluate hypotheses arising from other sources, and for the purpose of "generating" hypotheses. The data describing all 92 x 105 cross-tabulations are available to other investigators on floppy disk; write to Chief, Birth Defects and Genetic Diseases Branch, Centers for Disease Control, Atlanta, Georgia 30333. RP ERICKSON, JD (reprint author), CTR DIS CONTROL,BIRTH DEFECTS & GENET DIS BRANCH,ATLANTA,GA 30333, USA. NR 10 TC 66 Z9 68 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0040-3709 J9 TERATOLOGY JI Teratology PD JAN PY 1991 VL 43 IS 1 BP 41 EP 51 DI 10.1002/tera.1420430106 PG 11 WC Developmental Biology; Toxicology SC Developmental Biology; Toxicology GA ET417 UT WOS:A1991ET41700005 PM 2006471 ER PT J AU GOLDSMITH, R NAHMIAS, J SCHANTZ, P PELEG, H SHTAMLER, B ELON, J AF GOLDSMITH, R NAHMIAS, J SCHANTZ, P PELEG, H SHTAMLER, B ELON, J TI RESURGENCE OF HYDATID-DISEASE (ECHINOCOCCOSIS) IN COMMUNITIES IN NORTHERN ISRAEL SO TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE LA English DT Article AB Hydatid disease (echinococcosis), formerly endemic in the area of Israel, has occurred only sporadically in the past 40 years, mostly in immigrants. An unusual spatial and temporal cluster of surgically confirmed infections in northern Israel led to a review of echinococcosis hospital records. This revealed a resurgence of the disease in some rural and semirural Arab and Druze communities. Between 1960 and 1989, 224 cases of hydatid disease were surgically confirmed in residents of these communities. During this period, as the Arab-Druze population doubled, the mean annual surgical incidence of new cases per 100 000 rose 5-fold from 1.4 to 7.1. In Yirka, a Druze community of 7500 persons, from which no cases were known before 1970 and in which 52 cases were surgically confirmed thereafter, the mean annual surgical incidence for 1980-1989 rose to 53/100 000, to become one of the highly endemic areas of the world. The probable explanation of the outbreak is that, since 1967 with the opening of the border, importation of infected sheep has occurred from the hydatid-endemic West Bank region to individual homes in the communities in northern Israel. The sheep are raised to maturity in pens before home slaughtering; the offal, available to dogs, resulted in canine and then human infections. C1 KUVIN CTR STUDY INFECT & TROP DIS,JERUSALEM,ISRAEL. ZEVULIN CLIN,KIRAT MOTZKIN,ISRAEL. CTR DIS CONTROL,CTR INFECT DIS,PARASIT DIS BRANCH,ATLANTA,GA 30333. RAMBAM UNIV HOSP,DEPT CHEST SURG,HAIFA,ISRAEL. NAHARIA HOSP,DEPT GEN SURG,NAHARIYYA,ISRAEL. BEN GURION UNIV NEGEV,FAC HLTH SCI,DEPT MICROBIOL & IMMUNOL,BEER SHEVA,ISRAEL. RP GOLDSMITH, R (reprint author), UNIV CALIF SAN FRANCISCO,DEPT EPIDEMIOL & BIOSTAT,SAN FRANCISCO,CA 94143, USA. NR 13 TC 17 Z9 17 U1 1 U2 1 PU ROYAL SOC TROPICAL MEDICINE PI LONDON PA MANSON HOUSE 26 PORTLAND PLACE, LONDON, ENGLAND W1N 4EY SN 0035-9203 J9 T ROY SOC TROP MED H JI Trans. Roy. Soc. Trop. Med. Hyg. PD JAN-FEB PY 1991 VL 85 IS 1 BP 98 EP 100 DI 10.1016/0035-9203(91)90175-X PG 3 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA FB377 UT WOS:A1991FB37700036 PM 2068776 ER PT J AU BUSCH, MP YOUNG, MJ SAMSON, SM MOSLEY, JW WARD, JW PERKINS, HA AF BUSCH, MP YOUNG, MJ SAMSON, SM MOSLEY, JW WARD, JW PERKINS, HA TI RISK OF HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) TRANSMISSION BY BLOOD-TRANSFUSIONS BEFORE THE IMPLEMENTATION OF HIV-1 ANTIBODY SCREENING SO TRANSFUSION LA English DT Article ID IMMUNE-DEFICIENCY SYNDROME; LOOK-BACK; DONORS; AIDS; INFECTION; RECIPIENTS; COMPONENTS AB Little information is available regarding the risk of human immunodeficiency virus type 1 (HIV-1) infection for patients transfused before routine anti-HIV-1 screening of blood donors was instituted in March 1985. A model was developed for estimating both the proportion and the number of transfusion recipients in the San Francisco Bay area who were infected by HIV-1 during each of the 7 years preceding routine donor screening for anti-HIV-1. The model is based on analysis of 1) donation histories of HIV-1-infected donors identified at the regional blood center; 2) HIV-1 seroprevalence estimates for homosexual and bisexual men in San Francisco; and 3) HIV-1 infection and survival rates for recipients traced by the Transfusion Safety Study and Irwin Memorial Blood Centers' Look Back Program. The incidence of transfusion-associated HIV-1 infection is estimated to have risen rapidly from the first occurrence in 1978 to a peak in late 1982 of approximately 1.1 percent per transfused unit. The decrease after 1982 coincided with the implementation of high-risk donor deferral measures. It is estimated that, overall, approximately 2135 transfusion recipients were infected with HIV-1 in the San Francisco region alone. This number suggests a higher prevalence of transfusion-associated HIV-1 infection than has been generally recognized and indicates the need for continued tracing of potentially exposed recipients. The data also strongly support the efffectiveness of early donor education and self-exclusion measures and emphasize the importance of continued research and development in this area. C1 UNIV CALIF SAN FRANCISCO,DEPT LAB MED,SAN FRANCISCO,CA 94143. UNIV SO CALIF,SCH MED,DEPT MED,LOS ANGELES,CA 90033. CTR DIS CONTROL,AIDS PROGRAM,ATLANTA,GA 30333. FU NHLBI NIH HHS [P01-HL36589, N01-HB-4-7002, N01-HB-4-7003] NR 34 TC 104 Z9 107 U1 0 U2 2 PU AMER ASSOC BLOOD BANKS PI BETHESDA PA 8101 GLENBROOK RD, BETHESDA, MD 20814-2749 SN 0041-1132 J9 TRANSFUSION JI Transfusion PD JAN PY 1991 VL 31 IS 1 BP 4 EP 11 DI 10.1046/j.1537-2995.1991.31191096183.x PG 8 WC Hematology SC Hematology GA ET293 UT WOS:A1991ET29300002 PM 1986462 ER PT J AU ROTHENBERG, RB AF ROTHENBERG, RB TI METHODS IN EPIDEMIOLOGIC RESEARCH SO UPSALA JOURNAL OF MEDICAL SCIENCES LA English DT Article C1 CTR DIS CONTROL,NATL CTR CHRON DISEASE PREVENT & HLTH PROMOT,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SCANDINAVIAN UNIVERSITY PRESS PI OSLO PA PO BOX 2959 TOYEN, JOURNAL DIVISION CUSTOMER SERVICE, N-0608 OSLO, NORWAY SN 0300-9734 J9 UPSALA J MED SCI JI Ups. J. Med. Sci. PY 1991 SU 50 BP 66 EP 68 PG 3 WC Medicine, General & Internal SC General & Internal Medicine GA GN928 UT WOS:A1991GN92800023 ER PT J AU DONDERO, TJ PETERSEN, LR STLOUIS, ME AF DONDERO, TJ PETERSEN, LR STLOUIS, ME TI SEROPREVALENCE OF HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION AT SENTINEL HOSPITALS - REPLY SO NEW ENGLAND JOURNAL OF MEDICINE LA English DT Letter ID HIV INFECTION RP DONDERO, TJ (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 16 TC 0 Z9 0 U1 1 U2 1 PU MASS MEDICAL SOC PI BOSTON PA 10 SHATTUCK, BOSTON, MA 02115 SN 0028-4793 J9 NEW ENGL J MED JI N. Engl. J. Med. PD DEC 27 PY 1990 VL 323 IS 26 BP 1844 EP 1844 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EP376 UT WOS:A1990EP37600026 ER PT J AU MISHU, B SCHAFFNER, W AF MISHU, B SCHAFFNER, W TI A SURGEON WITH AIDS - REPLY SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Letter C1 VANDERBILT UNIV,MED CTR,SCH MED,NASHVILLE,TN 37232. RP MISHU, B (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 1 TC 2 Z9 2 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD DEC 26 PY 1990 VL 264 IS 24 BP 3147 EP 3148 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA EN614 UT WOS:A1990EN61400027 ER PT J AU MANN, VM DELAO, SL BRENES, M BRINTON, LA RAWLS, JA GREEN, M REEVES, WC RAWLS, WE AF MANN, VM DELAO, SL BRENES, M BRINTON, LA RAWLS, JA GREEN, M REEVES, WC RAWLS, WE TI OCCURRENCE OF IGA AND IGG ANTIBODIES TO SELECT PEPTIDES REPRESENTING HUMAN PAPILLOMAVIRUS TYPE-16 AMONG CERVICAL-CANCER CASES AND CONTROLS SO CANCER RESEARCH LA English DT Article C1 GORGAS MEM LAB,DIV EPIDEMIOL,PANAMA CITY,PANAMA. NCI,ENVIRONM EPIDEMIOL BRANCH,BETHESDA,MD 20892. ST LOUIS UNIV,INST MOLEC VIROL,ST LOUIS,MO 63110. CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,VIRAL EXANTHAMS & HERPESVIRUSES BRANCH,ATLANTA,GA 30333. RP MANN, VM (reprint author), MCMASTER UNIV,DEPT PATHOL,MOLEC VIROL & IMMUNOL PROGRAM,HAMILTON L8N 3Z5,ONTARIO,CANADA. RI Brinton, Louise/G-7486-2015 OI Brinton, Louise/0000-0003-3853-8562 FU NCI NIH HHS [N01-CP-41026, R01-CA-42042] NR 24 TC 67 Z9 69 U1 0 U2 0 PU AMER ASSOC CANCER RESEARCH PI PHILADELPHIA PA PUBLIC LEDGER BLDG, SUITE 816, 150 S. INDEPENDENCE MALL W., PHILADELPHIA, PA 19106 SN 0008-5472 J9 CANCER RES JI Cancer Res. PD DEC 15 PY 1990 VL 50 IS 24 BP 7815 EP 7819 PG 5 WC Oncology SC Oncology GA EM165 UT WOS:A1990EM16500016 PM 2174733 ER PT J AU REIDSANDEN, FL DOBBINS, JG SMITH, JS FISHBEIN, DB AF REIDSANDEN, FL DOBBINS, JG SMITH, JS FISHBEIN, DB TI RABIES SURVEILLANCE IN THE UNITED-STATES DURING 1989 SO JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION LA English DT Article RP REIDSANDEN, FL (reprint author), CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,ATLANTA,GA 30333, USA. NR 15 TC 23 Z9 23 U1 0 U2 0 PU AMER VETERINARY MEDICAL ASSOC PI SCHAUMBURG PA 1931 N MEACHAM RD SUITE 100, SCHAUMBURG, IL 60173-4360 SN 0003-1488 J9 J AM VET MED ASSOC JI J. Am. Vet. Med. Assoc. PD DEC 15 PY 1990 VL 197 IS 12 BP 1571 EP 1583 PG 13 WC Veterinary Sciences SC Veterinary Sciences GA EM549 UT WOS:A1990EM54900003 PM 2276949 ER PT J AU HEURTINROBERTS, S REISIN, E AF HEURTINROBERTS, S REISIN, E TI HEALTH BELIEFS, COMPLIANCE HYPERTENSION (REPRINTED FROM MMWR, VOL 39, PG 701-704, 1990) SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 CTR DIS CONTROL,INT HLTH PROGRAM OFF,DIV TECH SUPPORT,ATLANTA,GA 30333. CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,DIV SURVEILLANCE & EPIDEMIOL,ATLANTA,GA 30333. LOUISIANA STATE UNIV,MED CTR,DEPT MED,NEW ORLEANS,LA 70112. RP HEURTINROBERTS, S (reprint author), UNIV CALIF SAN FRANCISCO,DEPT EPIDEMIOL & BIOSTAT,SAN FRANCISCO,CA 94143, USA. NR 1 TC 6 Z9 6 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD DEC 12 PY 1990 VL 264 IS 22 BP 2864 EP 2864 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EL847 UT WOS:A1990EL84700003 ER PT J AU ANDERSON, BE BAUMSTARK, BR BELLINI, WJ AF ANDERSON, BE BAUMSTARK, BR BELLINI, WJ TI NUCLEOTIDE-SEQUENCE OF THE P34 GENE FROM RICKETTSIA-RICKETTSII SO NUCLEIC ACIDS RESEARCH LA English DT Note C1 CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,RESP & ENTEROVIRUS BRANCH,ATLANTA,GA 30333. GEORGIA STATE UNIV,DEPT BIOL,MICROBIAL & BIOCHEM SCI LAB,ATLANTA,GA 30303. RP ANDERSON, BE (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,VIRAL & RICKETTSIAL ZOONOSES BRANCH,ATLANTA,GA 30333, USA. RI Anderson, Burt/H-4449-2011 NR 3 TC 1 Z9 2 U1 0 U2 0 PU OXFORD UNIV PRESS UNITED KINGDOM PI OXFORD PA WALTON ST JOURNALS DEPT, OXFORD, ENGLAND OX2 6DP SN 0305-1048 J9 NUCLEIC ACIDS RES JI Nucleic Acids Res. PD DEC 11 PY 1990 VL 18 IS 23 BP 7168 EP 7168 DI 10.1093/nar/18.23.7168 PG 1 WC Biochemistry & Molecular Biology SC Biochemistry & Molecular Biology GA EP140 UT WOS:A1990EP14000088 PM 2124682 ER PT J AU RAVESLOOT, L YOUNG, WF AF RAVESLOOT, L YOUNG, WF TI CIGARETTE SALES TO MINORS - COLORADO, 1989 (REPRINTED FROM MMWR, 1990, 39, 794-801) SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,ATLANTA,GA 30333. COLORADO DEPT HLTH,DIV PREVENT PROGRAMS,DENVER,CO. RP RAVESLOOT, L (reprint author), FRONT RANGE COMMUN COLL,WESTMINSTER,ENGLAND. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD DEC 5 PY 1990 VL 264 IS 21 BP 2734 EP 2734 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EK537 UT WOS:A1990EK53700012 ER PT J AU KOPLAN, JP FALK, H GREEN, G AF KOPLAN, JP FALK, H GREEN, G TI PUBLIC-HEALTH LESSONS FROM THE BHOPAL CHEMICAL DISASTER SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Editorial Material C1 ALL INDIA INST MED SCI,NEW DELHI 110016,INDIA. HARVARD UNIV,SCH PUBL HLTH,BOSTON,MA 02115. RP KOPLAN, JP (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,A37,ATLANTA,GA 30333, USA. NR 9 TC 11 Z9 11 U1 1 U2 3 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD DEC 5 PY 1990 VL 264 IS 21 BP 2795 EP 2796 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA EK537 UT WOS:A1990EK53700037 PM 2232066 ER PT J AU ROPER, WL AF ROPER, WL TI MAKING PREVENTION A PRACTICAL REALITY SO ACADEMIC MEDICINE LA English DT Editorial Material C1 AGCY TOX,SUBST DIS REGISTRY,ATLANTA,GA. RP ROPER, WL (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 0 TC 1 Z9 1 U1 0 U2 0 PU HANLEY & BELFUS INC PI PHILADELPHIA PA 210 S 13TH ST, PHILADELPHIA, PA 19107 SN 1040-2446 J9 ACAD MED JI Acad. Med. PD DEC PY 1990 VL 65 IS 12 BP 736 EP 737 DI 10.1097/00001888-199012000-00005 PG 2 WC Education, Scientific Disciplines; Health Care Sciences & Services SC Education & Educational Research; Health Care Sciences & Services GA EN328 UT WOS:A1990EN32800006 PM 2252488 ER PT J AU TANGERMANN, RH MCCARTHY, BJ SCHMIDT, E AF TANGERMANN, RH MCCARTHY, BJ SCHMIDT, E TI COMPARING CAUSE-SPECIFIC INFANT-MORTALITY IN A WEST-GERMAN STATE AND THE UNITED-STATES-OF-AMERICA SO ACTA PAEDIATRICA SCANDINAVICA LA English DT Article DE INFANT MORTALITY; NEONATAL MORTALITY; POSTNEONATAL MORTALITY; BIRTH-WEIGHT; CAUSE OF DEATH AB The infant mortality rate in North Rhine Westphalia (NRW), the most populous West German state, has continuously been around 10% higher than the German national average in the post-war period. Using white singleton data from the US 1980 National Infant Mortality Surveillance project (NIMS) and similar 1980/1981 data from NRW we compared infant mortality by birthweight and cause to describe the distribution of excess mortality in NRW. The US infant mortality rate was 8.7 deaths per 1 000 live births, compared with 13.1/1000 for NRW (rate difference: 4.3/1 000). Of the 4.3/1 000 overall rate difference, 1.9/1 000 was attributable to neonatal deaths, 2.4/1 000 to postneonatal deaths. A major proportion, 2.0/1 000, of the overall rate difference of 4.3/1 000 was attributable to normal birthweight deaths postneonatally. 0.85/1 000 of this 2.0/1 000 rate difference was attributable to SIDS, 0.44/1 000 to external causes and 0.42/1 000 to infections. C1 UNIV DUSSELDORF,CHILDRENS HOSP,W-4000 DUSSELDORF 1,GERMANY. RP TANGERMANN, RH (reprint author), CTR DIS CONTROL,DIV REPROD HLTH,ATLANTA,GA 30333, USA. NR 7 TC 1 Z9 1 U1 0 U2 0 PU SCANDINAVIAN UNIVERSITY PRESS PI OSLO PA PO BOX 2959 TOYEN, JOURNAL DIVISION CUSTOMER SERVICE, N-0608 OSLO, NORWAY SN 0001-656X J9 ACTA PAEDIATR SCAND PD DEC PY 1990 VL 79 IS 12 BP 1143 EP 1149 PG 7 WC Pediatrics SC Pediatrics GA ER924 UT WOS:A1990ER92400003 PM 2085100 ER PT J AU SHAFFER, N HEDBERG, K DAVACHI, F LYAMBA, B BREMAN, JG MASISA, OS BEHETS, F HIGHTOWER, A NGUYENDINH, P AF SHAFFER, N HEDBERG, K DAVACHI, F LYAMBA, B BREMAN, JG MASISA, OS BEHETS, F HIGHTOWER, A NGUYENDINH, P TI TRENDS AND RISK-FACTORS FOR HIV-1 SEROPOSITIVITY AMONG OUTPATIENT CHILDREN, KINSHASA, ZAIRE SO AIDS LA English DT Article DE HIV; AIDS; PEDIATRIC; AFRICA; KINSHASA; ZAIRE; ANEMIA; BLOOD TRANSFUSIONS; ALRI; MALARIA ID HUMAN IMMUNODEFICIENCY VIRUS; BLOOD-TRANSFUSIONS; FALCIPARUM-MALARIA; TRANSMISSION; ASSOCIATION; INFECTION; ANTIBODY; AIDS AB To investigate recent trends in pediatric HIV-1 infection and the early impact of a blood screening program begun in one hospital in 1987 in Kinshasa, Zaire, we evaluated 1110 consecutive children seen in the pediatric emergency ward of the city's largest hospital in November 1988. The HIV-1 seroprevalence was 5.0%, not significantly higher than the rate of 3.8% found in 1986 (P = 0.2). The seropositivity rate was bimodally distributed; children < 6 months of age had a higher rate (12.6%) than children 6-11 months old (1.9%; OR = 7.6; P < 0.0001) and children 1-13 years old (4.1%; OR = 3.4; P < 0.0001). Seropositive children greater-than-or-equal-to 1 year of age were more likely than seronegative children to be anemic and to have signs of malnutrition. A previous blood transfusion was associated with HIV-1 seropositivity among children greater-than-or-equal-to 1 year of age (OR = 5.4. P < 0.0005), but not among younger children. Fifty-two per cent of seropositive children greater-than-or-equal-to 1 year of age had received a transfusion (etiological fraction = 42%). The association with seropositivity was higher for those who had received a transfusion before 1987 than for those who had received a transfusion since 1987 (OR = 4.8, P = 0.01). These findings suggest a relatively stable, high pediatric HIV-1 seroprevalence in Kinshasa and a decreased but continued risk of transfusions. Expansion of currently limited blood transfusion screening programs, and the development of new strategies for limiting transfusions and preventing severe anemia, are needed. C1 PROJET SIDA,KINSHASA,ZAIRE. CTR DIS CONTROL,DIV PARASIT DIS,ATLANTA,GA 30333. MAMA YEMO HOSP,DEPT PEDIAT,KINSHASA,ZAIRE. RP SHAFFER, N (reprint author), CTR DIS CONTROL,MALARIA BRANCH,DIV HIV AIDS E45,ATLANTA,GA 30333, USA. NR 22 TC 29 Z9 29 U1 0 U2 0 PU RAPID SCIENCE PUBLISHERS PI LONDON PA 2-6 BOUNDARY ROW, LONDON, ENGLAND SE1 8NH SN 0269-9370 J9 AIDS JI Aids PD DEC PY 1990 VL 4 IS 12 BP 1231 EP 1236 DI 10.1097/00002030-199012000-00008 PG 6 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA ER950 UT WOS:A1990ER95000008 PM 2088400 ER PT J AU EKBOM, A ADAMI, HO HELMICK, CG JONZON, A ZACK, MM AF EKBOM, A ADAMI, HO HELMICK, CG JONZON, A ZACK, MM TI PERINATAL RISK-FACTORS FOR INFLAMMATORY BOWEL-DISEASE - A CASE-CONTROL STUDY SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Article C1 CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMET,ATLANTA,GA 30333. UNIV HOSP UPPSALA,DEPT PEDIAT,S-75185 UPPSALA,SWEDEN. RP EKBOM, A (reprint author), UNIV HOSP UPPSALA,DEPT SURG,CANC EPIDEMIOL UNIT,S-75185 UPPSALA,SWEDEN. NR 31 TC 125 Z9 126 U1 0 U2 1 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD DEC PY 1990 VL 132 IS 6 BP 1111 EP 1119 PG 9 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EN620 UT WOS:A1990EN62000011 PM 2260543 ER PT J AU BOYLE, CA DECOUFLE, P AF BOYLE, CA DECOUFLE, P TI NATIONAL SOURCES OF VITAL STATUS INFORMATION - EXTENT OF COVERAGE AND POSSIBLE SELECTIVITY IN REPORTING - REPLY SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Letter RP BOYLE, CA (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 3 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD DEC PY 1990 VL 132 IS 6 BP 1197 EP 1197 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EN620 UT WOS:A1990EN62000021 ER PT J AU CATES, W AF CATES, W TI ACQUIRED-IMMUNODEFICIENCY-SYNDROME SEXUALLY-TRANSMITTED DISEASES, AND EPIDEMIOLOGY - PAST LESSONS, PRESENT KNOWLEDGE, AND FUTURE OPPORTUNITIES SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Letter RP CATES, W (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,DIV STD HIV PREVENT,ATLANTA,GA 30333, USA. NR 2 TC 0 Z9 0 U1 1 U2 1 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD DEC PY 1990 VL 132 IS 6 BP 1199 EP 1199 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EN620 UT WOS:A1990EN62000025 ER PT J AU WENGER, JD HARRISON, LH HIGHTOWER, A BROOME, CV AF WENGER, JD HARRISON, LH HIGHTOWER, A BROOME, CV TI DAY-CARE CHARACTERISTICS ASSOCIATED WITH HAEMOPHILUS-INFLUENZAE DISEASE SO AMERICAN JOURNAL OF PUBLIC HEALTH LA English DT Article RP WENGER, JD (reprint author), CTR DIS CONTROL,MENINGITIS & SPECIAL PATHOGENS BRANCH,BLDG 1,ROOM 5409,ATLANTA,GA 30333, USA. NR 17 TC 14 Z9 14 U1 0 U2 1 PU AMER PUBLIC HEALTH ASSN INC PI WASHINGTON PA 1015 FIFTEENTH ST NW, WASHINGTON, DC 20005 SN 0090-0036 J9 AM J PUBLIC HEALTH JI Am. J. Public Health PD DEC PY 1990 VL 80 IS 12 BP 1455 EP 1458 DI 10.2105/AJPH.80.12.1455 PG 4 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EJ980 UT WOS:A1990EJ98000007 PM 2240329 ER PT J AU COLLINS, WE NUSSENZWEIG, RS RUEBUSH, TK BATHURST, IC NARDIN, EH GIBSON, HL CAMPBELL, GH BARR, PJ BRODERSON, JR SKINNER, JC FILIPSKI, VK STANFILL, PS ROBERTS, JM WILSON, CL AF COLLINS, WE NUSSENZWEIG, RS RUEBUSH, TK BATHURST, IC NARDIN, EH GIBSON, HL CAMPBELL, GH BARR, PJ BRODERSON, JR SKINNER, JC FILIPSKI, VK STANFILL, PS ROBERTS, JM WILSON, CL TI FURTHER-STUDIES ON THE IMMUNIZATION OF SAIMIRI-SCIUREUS-BOLIVIENSIS WITH RECOMBINANT VACCINES BASED ON THE CIRCUMSPOROZOITE PROTEIN OF PLASMODIUM-VIVAX SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID PLASMODIUM-VIVAX; I STRAIN AB Reported are the results of a trial in squirrel monkeys of 2 Plasmodium vivax malaria vaccine candidates based on the circumsporozoite (CS) protein, namely, rPvCs-2 and rPvCS-3. Compared with an earlier recombinant P. vivax CS construct, rPvCS-1 rPvCS-2 has an additional 24 amino acids at the C-terminal, which includes the thrombospondin region of homology and a putative T cell epitope. The rPvCS-3 was generated from a chemically synthesized gene that contained an additional 54 amino acids at the amino terminus and terminates at the same carboxy-terminal amino acid as rPvCS-2. In addition, rPvCS-3 contained only 1 each of the repeat sequences DRADGQPAG and DRAAGQPAG. Both antigens were administered with alum as adjuvant. Neither formulation caused toxic side effects and both recombinant molecules induced high antibody titers. Two monkeys were protected against sporozoite challenge by immunization with rPvCS-2 antigen, while none of the rPvCS-3 immunized animals displayed any degree of protection. While there was no correlation between protection and antibody titer or the in vitro proliferation of lymphocytes in response to the antigens, this is further evidence to support the role of the repeating epitopes in generating protective immunity. C1 CTR DIS CONTROL,CTR INFECT DIS,OFF SCI SERV,ATLANTA,GA 30333. NYU MED CTR,DEPT MED & MOLEC PARASITOL,NEW YORK,NY 10016. CHIRON CORP,EMERVILLE,CA. RP COLLINS, WE (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,ATLANTA,GA 30333, USA. FU NCRR NIH HHS [RR-00165]; PHS HHS [1R29 A125085-01] NR 12 TC 22 Z9 22 U1 0 U2 1 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD DEC PY 1990 VL 43 IS 6 BP 576 EP 583 PG 8 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA ET983 UT WOS:A1990ET98300002 PM 1702586 ER PT J AU LUNDEGARDH, G ADAMI, HO HELMICK, C ZACK, M AF LUNDEGARDH, G ADAMI, HO HELMICK, C ZACK, M TI THE RISK OF LARGE-BOWEL CANCER AFTER PARTIAL GASTRECTOMY FOR BENIGN ULCER DISEASE SO ANNALS OF SURGERY LA English DT Article C1 UNIV HOSP UPPSALA,DEPT SURG,S-75185 UPPSALA,SWEDEN. CENT HOSP BODEN,DEPT SURG,BODEN,SWEDEN. CTR DIS CONTROL,ATLANTA,GA 30333. FU NCI NIH HHS [5 RO1 CA 40264-02] NR 32 TC 7 Z9 7 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0003-4932 J9 ANN SURG JI Ann. Surg. PD DEC PY 1990 VL 212 IS 6 BP 714 EP 719 DI 10.1097/00000658-199012000-00010 PG 6 WC Surgery SC Surgery GA EN332 UT WOS:A1990EN33200010 PM 2256763 ER PT J AU BRANN, E AF BRANN, E TI THE ASSOCIATION OF SELECTED CANCERS WITH SERVICE IN THE UNITED-STATES MILITARY IN VIETNAM .1. NON-HODGKINS-LYMPHOMA SO ARCHIVES OF INTERNAL MEDICINE LA English DT Article RP BRANN, E (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333, USA. NR 50 TC 32 Z9 32 U1 1 U2 1 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0003-9926 J9 ARCH INTERN MED JI Arch. Intern. Med. PD DEC PY 1990 VL 150 IS 12 BP 2473 EP 2483 PG 11 WC Medicine, General & Internal SC General & Internal Medicine GA EM108 UT WOS:A1990EM10800005 ER PT J AU BRANN, E AF BRANN, E TI THE ASSOCIATION OF SELECTED CANCERS WITH SERVICE IN THE UNITED-STATES MILITARY IN VIETNAM .2. SOFT-TISSUE AND OTHER SARCOMAS SO ARCHIVES OF INTERNAL MEDICINE LA English DT Article RP BRANN, E (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333, USA. NR 41 TC 20 Z9 20 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0003-9926 J9 ARCH INTERN MED JI Arch. Intern. Med. PD DEC PY 1990 VL 150 IS 12 BP 2485 EP 2492 PG 8 WC Medicine, General & Internal SC General & Internal Medicine GA EM108 UT WOS:A1990EM10800006 ER PT J AU BRANN, E AF BRANN, E TI THE ASSOCIATION OF SELECTED CANCERS WITH SERVICE IN THE UNITED-STATES MILITARY IN VIETNAM .3. HODGKINS-DISEASE, NASAL CANCER, NASOPHARYNGEAL CANCER, AND PRIMARY LIVER-CANCER SO ARCHIVES OF INTERNAL MEDICINE LA English DT Article RP BRANN, E (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333, USA. NR 38 TC 21 Z9 21 U1 1 U2 1 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0003-9926 J9 ARCH INTERN MED JI Arch. Intern. Med. PD DEC PY 1990 VL 150 IS 12 BP 2495 EP 2505 PG 11 WC Medicine, General & Internal SC General & Internal Medicine GA EM108 UT WOS:A1990EM10800007 ER PT J AU MYERS, GL SCHAP, D SMITH, SJ COOPER, GR HARTMANN, AE GILMORE, B SUENRAM, CA RAY, DH AF MYERS, GL SCHAP, D SMITH, SJ COOPER, GR HARTMANN, AE GILMORE, B SUENRAM, CA RAY, DH TI COLLEGE-OF-AMERICAN-PATHOLOGISTS-CENTERS-FOR-DISEASE-CONTROL COLLABORATIVE STUDY FOR EVALUATING REFERENCE MATERIALS FOR TOTAL SERUM-CHOLESTEROL MEASUREMENTS SO ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE LA English DT Article C1 COLL AMER PATHOLOGISTS,NORTHFIELD,IL. CONE BIOTECH INC,SEQUIN,TX. RP MYERS, GL (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV ENVIRONM HLTH LAB SCI,ATLANTA,GA 30333, USA. NR 24 TC 11 Z9 11 U1 0 U2 0 PU COLLEGE AMER PATHOLOGISTS PI NORTHFIELD PA C/O KIMBERLY GACKI, 325 WAUKEGAN RD, NORTHFIELD, IL 60093-2750 SN 0003-9985 J9 ARCH PATHOL LAB MED JI Arch. Pathol. Lab. Med. PD DEC PY 1990 VL 114 IS 12 BP 1199 EP 1205 PG 7 WC Medical Laboratory Technology; Medicine, Research & Experimental; Pathology SC Medical Laboratory Technology; Research & Experimental Medicine; Pathology GA EN302 UT WOS:A1990EN30200017 PM 2252414 ER PT J AU GALINSKY, TL ROSA, RR WHEELER, DD AF GALINSKY, TL ROSA, RR WHEELER, DD TI ASSESSING MUSCULAR FATIGUE WITH A PORTABLE TREMOR MEASUREMENT SYSTEM SUITABLE FOR FIELD USE SO BEHAVIOR RESEARCH METHODS INSTRUMENTS & COMPUTERS LA English DT Article ID NORMAL HAND TREMOR; PHYSIOLOGICAL TREMOR; EXTENDED WORKDAYS; STRETCH REFLEX; PERFORMANCE; ALERTNESS; ELECTROMYOGRAM; FORCE C1 UNIV CINCINNATI,CINCINNATI,OH 45221. RP GALINSKY, TL (reprint author), NIOSH,ROBERT A TAFT LABS,DIV BIOMED & BEHAV SCI,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 46 TC 7 Z9 7 U1 2 U2 5 PU PSYCHONOMIC SOC INC PI AUSTIN PA 1710 FORTVIEW RD, AUSTIN, TX 78704 SN 0743-3808 J9 BEHAV RES METH INSTR JI Behav. Res. Methods Instr. Comput. PD DEC PY 1990 VL 22 IS 6 BP 507 EP 516 DI 10.3758/BF03204434 PG 10 WC Psychology, Mathematical; Psychology, Experimental SC Psychology GA EP509 UT WOS:A1990EP50900003 ER PT J AU LANGHOLZ, B THOMAS, D CHEN, TJ RHODES, P AF LANGHOLZ, B THOMAS, D CHEN, TJ RHODES, P TI TESTS OF EFFECT IN 1-J MATCHED CASE-CONTROL STUDIES BASED ON A MODIFIED LIKELIHOOD APPROACH SO BIOMETRIKA LA English DT Article C1 CTR DIS CONTROL,DIV INJURY EPIDEMIOL & CONTROL,ATLANTA,GA 30333. RP LANGHOLZ, B (reprint author), UNIV SO CALIF,DEPT PREVENT MED,LOS ANGELES,CA 90033, USA. NR 4 TC 0 Z9 0 U1 1 U2 2 PU BIOMETRIKA TRUST PI LONDON PA UNIV COLLEGE LONDON GOWER ST-BIOMETRIKA OFFICE, LONDON, ENGLAND WC1E 6BT SN 0006-3444 J9 BIOMETRIKA JI Biometrika PD DEC PY 1990 VL 77 IS 4 BP 897 EP 900 PG 4 WC Biology; Mathematical & Computational Biology; Statistics & Probability SC Life Sciences & Biomedicine - Other Topics; Mathematical & Computational Biology; Mathematics GA EM616 UT WOS:A1990EM61600022 ER PT J AU GUNTER, EW TWITE, DB AF GUNTER, EW TWITE, DB TI IMPROVED MATERIALS FOR LONG-TERM QUALITY-CONTROL ASSESSMENT OF ERYTHROCYTE FOLATE ANALYSIS SO CLINICAL CHEMISTRY LA English DT Note RP GUNTER, EW (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH,DIV ENVIRONM HLTH LAB SCI,NUTR BIOCHEM BRANCH,BLD 17,ATLANTA,GA 30333, USA. NR 3 TC 4 Z9 4 U1 0 U2 0 PU AMER ASSOC CLINICAL CHEMISTRY PI WASHINGTON PA 2101 L STREET NW, SUITE 202, WASHINGTON, DC 20037-1526 SN 0009-9147 J9 CLIN CHEM JI Clin. Chem. PD DEC PY 1990 VL 36 IS 12 BP 2139 EP 2139 PG 1 WC Medical Laboratory Technology SC Medical Laboratory Technology GA EP614 UT WOS:A1990EP61400028 PM 2253365 ER PT J AU KELLERMANN, AL MERCY, JA AF KELLERMANN, AL MERCY, JA TI SEX, LIES AND HANDGUNS - SHOULD WOMEN BUY FIREARMS FOR SELF-DEFENSE SO CLINICAL RESEARCH LA English DT Meeting Abstract C1 UNIV TENNESSEE,CTR HLTH SCI,MEMPHIS,TN 38163. CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 2 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 SN 0009-9279 J9 CLIN RES JI Clin. Res. PD DEC PY 1990 VL 38 IS 4 BP A1003 EP A1003 PG 1 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA EN539 UT WOS:A1990EN53900460 ER PT J AU MCNICHOLL, JM OFTUNG, F SHINNICK, TM KARR, RW AF MCNICHOLL, JM OFTUNG, F SHINNICK, TM KARR, RW TI EFFECT OF VARIABLE HLA-DR4-BETA-1 RESIDUES ON T-CELL RECOGNITION OF A MYCOBACTERIAL HEAT-SHOCK PROTEIN SO CLINICAL RESEARCH LA English DT Meeting Abstract C1 EMORY UNIV,ATLANTA,GA 30322. NORWEGIAN RADIUM HOSP,OSLO 3,NORWAY. CTR DIS CONTROL,ATLANTA,GA 30333. UNIV IOWA,IOWA CITY,IA 52242. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 SN 0009-9279 J9 CLIN RES JI Clin. Res. PD DEC PY 1990 VL 38 IS 4 BP A949 EP A949 PG 1 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA EN539 UT WOS:A1990EN53900183 ER PT J AU RAMSEY, KM HOKANSON, JA STEURER, FJ LONG, EG AF RAMSEY, KM HOKANSON, JA STEURER, FJ LONG, EG TI SEROPREVALENCE OF TOXOPLASMA, AMEBIASIS, AND LEISHMANIASIS AMONG RURAL HAITIANS SO CLINICAL RESEARCH LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. UNIV TEXAS,MED BRANCH,GALVESTON,TX 77550. UNIV SO ALABAMA,MOBILE,AL 36688. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 SN 0009-9279 J9 CLIN RES JI Clin. Res. PD DEC PY 1990 VL 38 IS 4 BP A923 EP A923 PG 1 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA EN539 UT WOS:A1990EN53900041 ER PT J AU GOTTLIEB, NH GALAVOTTI, C MCCUAN, RA MCALISTER, AL AF GOTTLIEB, NH GALAVOTTI, C MCCUAN, RA MCALISTER, AL TI SPECIFICATION OF A SOCIAL COGNITIVE MODEL PREDICTING SMOKING CESSATION IN A MEXICAN-AMERICAN POPULATION - A PROSPECTIVE-STUDY SO COGNITIVE THERAPY AND RESEARCH LA English DT Article C1 UNIV TEXAS,HLTH SCI CTR,HOUSTON,TX 77225. CTR DIS CONTROL,ATLANTA,GA 30333. RP GOTTLIEB, NH (reprint author), UNIV TEXAS,DEPT KINESIOL & HLTH EDUC,BELLMONT HALL,ROOM 222,AUSTIN,TX 78712, USA. NR 36 TC 31 Z9 32 U1 0 U2 1 PU PLENUM PUBL CORP PI NEW YORK PA 233 SPRING ST, NEW YORK, NY 10013 SN 0147-5916 J9 COGNITIVE THER RES JI Cogn. Ther. Res. PD DEC PY 1990 VL 14 IS 6 BP 529 EP 542 DI 10.1007/BF01173362 PG 14 WC Psychology, Clinical SC Psychology GA EM303 UT WOS:A1990EM30300001 ER PT J AU SCHLEIFER, LM OKOGBAA, OG AF SCHLEIFER, LM OKOGBAA, OG TI SYSTEM RESPONSE-TIME AND METHOD OF PAY - CARDIOVASCULAR STRESS EFFECTS IN COMPUTER-BASED TASKS SO ERGONOMICS LA English DT Article DE COMPUTERS; WORKLOAD; CARDIOVASCULAR STRESS; PSYCHOPHYSIOLOGY ID WORK AB Psychophysiological effects of computer system response time (slow vs. rapid) and method of pay (incentive vs. nonincentive) were assessed in a computer-based data entry task among forty-five professional typists. Cardiovascular responses (i.e., heart rate and blood pressure) were monitored on a regular basis over four consecutive workdays. Heart rate and blood pressure did not vary significantly with slow or rapid response times. Incentive pay, however, significantly increased blood pressure and decreased heart rate variability across the workdays compared to nonincentive pay. Irrespective of response time or method of pay, performance of the data entry task for sustained periods of time was associated with reduced heart rate and increased heart rate variability. This temporal effect was indicative of reduced effort or increased mental fatigue. The results of this study suggest that incentive pay programmes in data entry work may produce stress-related physiological reactivity among healthy workers. C1 UNIV CINCINNATI,DEPT MECH & IND ENGN,CINCINNATI,OH 45221. RP SCHLEIFER, LM (reprint author), NIOSH,DIV BIOMED & BEHAV SCI,4676 COLUMBIA PKWY,C-24,CINCINNATI,OH 45226, USA. NR 25 TC 24 Z9 24 U1 1 U2 2 PU TAYLOR & FRANCIS LTD PI LONDON PA ONE GUNDPOWDER SQUARE, LONDON, ENGLAND EC4A 3DE SN 0014-0139 J9 ERGONOMICS JI Ergonomics PD DEC PY 1990 VL 33 IS 12 BP 1495 EP 1509 DI 10.1080/00140139008925349 PG 15 WC Engineering, Industrial; Ergonomics; Psychology, Applied; Psychology SC Engineering; Psychology GA EP131 UT WOS:A1990EP13100007 PM 2286196 ER PT J AU CORIGLIONE, G STELLA, G GAFA, L SPATA, G OLIVERI, S PADHYE, AA AJELLO, L AF CORIGLIONE, G STELLA, G GAFA, L SPATA, G OLIVERI, S PADHYE, AA AJELLO, L TI NEOSARTORYA-FISCHERI VAR FISCHERI (WEHMER) MALLOCH AND CAIN 1972 (ANAMORPH - ASPERGILLUS-FISCHERIANUS SAMSON AND GAMS 1985) AS A CAUSE OF MYCOTIC KERATITIS SO EUROPEAN JOURNAL OF EPIDEMIOLOGY LA English DT Article DE MYCOTIC KERATITIS; NEOSARTORYA-FISCHERI (ASPERGILLUS-FISCHERIANUS) AB The first case of mycotic keratitis caused by Neosartorya fischeri var. fischeri the teleomorph of Aspergillus fischerianus, is described. The patient, a 62-year-old man, had no history of trauma to his infected left eye. The infection progressed despite treatment with ketoconazole and the eye had to be eviscerated. Histological studies revealed the presence of hyaline, septate mycelium in the eye tissue. Cultures gave rise to a thermotolerant mould that developed both its asexual and sexual forms. The isolate was identified on the basis of the morphologic features of its anamorphic and teleomorphic states. In the literature only seven other species of Aspergillus have been unequivocally reported as causing mycotic keratitis. C1 CTR DIS CONTROL,DIV MYCOT DIS,1600 CLIFTON RD,ATLANTA,GA 30333. NR 0 TC 25 Z9 25 U1 1 U2 3 PU KLUWER ACADEMIC PUBL PI DORDRECHT PA SPUIBOULEVARD 50, PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS SN 0393-2990 J9 EUR J EPIDEMIOL JI Eur. J. Epidemiol. PD DEC PY 1990 VL 6 IS 4 BP 382 EP 385 DI 10.1007/BF00151712 PG 4 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EP144 UT WOS:A1990EP14400007 PM 2091938 ER PT J AU WINN, FJ PUTZANDERSON, V AF WINN, FJ PUTZANDERSON, V TI VIBRATION THRESHOLDS AS A FUNCTION OF AGE AND DIAGNOSIS OF CARPAL-TUNNEL SYNDROME - A PRELIMINARY-REPORT SO EXPERIMENTAL AGING RESEARCH LA English DT Note ID NEUROPATHIES AB To determine if vibration thresholds vary independently with age and carpal tunnel syndrome (CTS), 61 subjects, including 27 diagnosed with carpal tunnel-induced neuropathy, and 34 non-CTS controls, ranging in age from 20 to 65 years, were tested using the Optacon(R), a device used to assess vibration thresholds. No statistically significant interaction was found between the age and diagnosis factors. Results did confirm the findings of previous studies that vibration thresholds increased with age and that thresholds were elevated within the CTS group, compared to the controls. These results indicate that age-adjusted norms for vibration threshold data need to be developed. Without age-adjusted norms, screening programs for CTS that rely on vibration threshold data are likely to generate high levels of false positives, particularly for workers over 40 years of age. RP WINN, FJ (reprint author), NIOSH,ROBERT A TAFT LABS,DIV BIOMED & BEHAV SCI,APPL PSYCHOL & ERGONOM BRANCH,CINCINNATI,OH 45230, USA. NR 22 TC 7 Z9 7 U1 1 U2 1 PU TAYLOR & FRANCIS PI BRISTOL PA 1900 FROST ROAD, SUITE 101, BRISTOL, PA 19007-1598 SN 0361-073X J9 EXP AGING RES JI Exp. Aging Res. PD WIN PY 1990 VL 16 IS 4 BP 221 EP 224 PG 4 WC Geriatrics & Gerontology; Psychology SC Geriatrics & Gerontology; Psychology GA FH972 UT WOS:A1990FH97200006 PM 2131268 ER PT J AU KATHARIOU, S PINE, L GEORGE, V CARLONE, GM HOLLOWAY, BP AF KATHARIOU, S PINE, L GEORGE, V CARLONE, GM HOLLOWAY, BP TI NONHEMOLYTIC LISTERIA-MONOCYTOGENES MUTANTS THAT ARE ALSO NONINVASIVE FOR MAMMALIAN-CELLS IN CULTURE - EVIDENCE FOR COORDINATE REGULATION OF VIRULENCE SO INFECTION AND IMMUNITY LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,MENINGITIS & SPECIAL PATHOGENS BRANCH,ATLANTA,GA 30333. CTR DIS CONTROL,CTR INFECT DIS,CELL CULTURE BIOL PROD BRANCH,SCI RESOURCES PROGRAM,ATLANTA,GA 30333. CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,ATLANTA,GA 30333. NR 42 TC 44 Z9 45 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0019-9567 J9 INFECT IMMUN JI Infect. Immun. PD DEC PY 1990 VL 58 IS 12 BP 3988 EP 3995 PG 8 WC Immunology; Infectious Diseases SC Immunology; Infectious Diseases GA EK781 UT WOS:A1990EK78100026 PM 2123830 ER PT J AU BUCK, GM COOKFAIR, DL MICHALEK, AM NASCA, PC STANDFAST, SJ SEVER, LE AF BUCK, GM COOKFAIR, DL MICHALEK, AM NASCA, PC STANDFAST, SJ SEVER, LE TI TIMING OF PRENATAL-CARE AND RISK OF SUDDEN-INFANT-DEATH-SYNDROME SO INTERNATIONAL JOURNAL OF EPIDEMIOLOGY LA English DT Article ID EPIDEMIOLOGY; PROJECT; APNEA AB Sudden infant death syndrome (SIDS) is the leading cause of death during post-neonatal life. Mothers whose infants succumb to SIDS are reported to initiate prenatal care later than control mothers. Previous studies have not always controlled for socioeconomic status (SES) of mothers or other potential confounders such as gestational age or birthweight of infants. The purpose of this study was to assess whether timing of prenatal care adjusted for these potential confounders was an independent risk factor for SIDS. SIDS cases (N = 148) were identified from the Upstate New York livebirth cohort for 1974 (N = 132 948) and compared to randomly selected controls (N = 355) who were frequency-matched on maternal age, race, parity and residence and infant's birth date. Data were abstracted from matched vital certificates (97% response), hospital delivery records (89% response) and selected sample of autopsy reports (100% response). Odds ratios (OR) and 95% confidence intervals (Cl) were obtained using unconditional logistic regression. A significant inverse relationship was observed for number of prenatal visits and risk of SIDS; a significant direct relationship was observed between trimester prenatal care initiated and risk of SIDS. The results suggest that timing of prenatal care is important in assessing SIDS risk even after adjusting for potential confounders of early prenatal care utilization. C1 CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV BIRTH DEFECTS & DEV DISABIL,ATLANTA,GA 30333. NEW YORK STATE DEPT HLTH,ROSWELL PK MEM INST,DEPT EDUC,BUFFALO,NY 14263. NEW YORK STATE DEPT HLTH,ROSWELL PK MEM INST,DEPT BIOMATH,BUFFALO,NY 14263. NEW YORK STATE DEPT HLTH,BUR CANC EPIDEMIOL,ALBANY,NY 12237. NEW YORK STATE DEPT HLTH,INJURY CONTROL PROGRAM,ALBANY,NY 12237. RP BUCK, GM (reprint author), SUNY BUFFALO,SCH MED & BIOMED SCI,DEPT SOCIAL & PREVENT MED,2211 MAIN ST,BLDG A,BUFFALO,NY 14214, USA. OI Buck Louis, Germaine/0000-0002-1774-4490 NR 24 TC 5 Z9 6 U1 0 U2 0 PU OXFORD UNIV PRESS UNITED KINGDOM PI OXFORD PA WALTON ST JOURNALS DEPT, OXFORD, ENGLAND OX2 6DP SN 0300-5771 J9 INT J EPIDEMIOL JI Int. J. Epidemiol. PD DEC PY 1990 VL 19 IS 4 BP 991 EP 996 DI 10.1093/ije/19.4.991 PG 6 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA ET595 UT WOS:A1990ET59500033 PM 2084033 ER PT J AU EIDSON, M LYBARGER, JA PARSONS, JE MACCORMACK, JN FREEMAN, JI AF EIDSON, M LYBARGER, JA PARSONS, JE MACCORMACK, JN FREEMAN, JI TI RISK-FACTORS FOR TORNADO INJURIES SO INTERNATIONAL JOURNAL OF EPIDEMIOLOGY LA English DT Article ID DISASTERS AB Tornadoes in North and South Carolina on 28 March 1984 caused 252 people to be injured seriously enough to require hospitalization and 59 to be killed. To evaluate risk factors, we gathered information on 238 (94%) of those hospitalized and 46 (78%) of those killed. Those hospitalized or decreased had statistically significantly more deep cuts, concussions, unconsciousness and broken bones than those with them at the time of the tornado who were not hospitalized or killed. People living in mobile homes were more likely to be hospitalized or die than people occupying conventional houses. Other risk factors for hospitalization or death included advanced age (60+ years), no physical protection (not having been covered with a blanket or other object), having been struck by broken window glass or other falling objects, home lifted off its foundation, collapsed ceiling or floor, or walls blown away. More awareness of the tornado risk before it strikes and better adherence to tornado protection guidelines could reduce injuries and deaths in the future. C1 N CAROLINA DEPT HUMAN RESOURCES,DIV HLTH SERV,RALEIGH,NC 27609. CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV FIELD SERV,ATLANTA,GA 30333. NR 28 TC 25 Z9 26 U1 0 U2 1 PU OXFORD UNIV PRESS UNITED KINGDOM PI OXFORD PA WALTON ST JOURNALS DEPT, OXFORD, ENGLAND OX2 6DP SN 0300-5771 J9 INT J EPIDEMIOL JI Int. J. Epidemiol. PD DEC PY 1990 VL 19 IS 4 BP 1051 EP 1056 DI 10.1093/ije/19.4.1051 PG 6 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA ET595 UT WOS:A1990ET59500040 PM 2083989 ER PT J AU HATCH, DL VREULS, RC TOOLE, MJ MOTEETEE, MM MONOANG, I NGATANE, CM GITTELMAN, DM WALDMAN, RJ AF HATCH, DL VREULS, RC TOOLE, MJ MOTEETEE, MM MONOANG, I NGATANE, CM GITTELMAN, DM WALDMAN, RJ TI THE EFFECTIVE CASE-MANAGEMENT OF CHILDHOOD DIARRHEA WITH ORAL REHYDRATION THERAPY IN THE KINGDOM OF LESOTHO SO INTERNATIONAL JOURNAL OF EPIDEMIOLOGY LA English DT Article ID CHILDREN AB In Lesotho prior to 1986, diarrhoea was the leading cause of hospital mortality in children < 5 years of age. At the Queen Elizabeth II Hospital, diarrhoea-related admissions as a proportion of all admissions in children < 5 years of age declined from 23% in the year prior to the opening of the Oral Rehydration Therapy Unit (ORTU) to 13% in the first nine months of 1987 (p < 0.05). In addition, the case-fatality ratio of children treated in the ORTU declined from 1.4% in the first quarter of 1986 to zero in the second and third quarters of 1987 (p < 0.05). In a case-control study conducted to identify reasons for children failing ORTU treatment, factors associated with an increased risk of hospitalization included male gender (odds ratio [OR] = 4.9; 95% confidence limits [CL] = 2.0, 11.9), fever greater-than-or-equal-to 38.5-degrees-C (OR = 2.0; CL = 1.2, 3.3), undernutrition (OR = 3.2; CL = 1.1, 9.4), and moderate dehydration (OR = 2.3; CL = 1.2, 4.4) or severe dehydration (OR = 12.1; CL = 3.8, 38.5). Breastfed children < 2 years of age were at decreased risk of hospitalization (OR = 0.4; CL = 0.2, 0.7). At this major hospital in Lesotho, the standardization of outpatient treatment for diarrhoea with oral rehydration salts (ORS) in the context of an ORTU resulted in a marked decreased in diarrhoea-associated hospitalization and deaths in children < 5 years of age. C1 QUEEN ELIZABETH II HOSP,DEPT PAEDIAT,MASERU,LESOTHO. MINIST HLTH,DIV FAMILY HLTH,MASERU,LESOTHO. US AGCY INT DEV,COMBATTING CHILDHOOD COMMUNICABLE DIS,MASERU,LESOTHO. EMORY UNIV,MASTERS PUBL HLTH PROGRAM,ATLANTA,GA 30322. RP HATCH, DL (reprint author), CTR DIS CONTROL,INT HLTH PROGRAM OFF,DIV TECH SUPPORT,1600 CLIFTON RD,MS F03,ATLANTA,GA 30333, USA. NR 9 TC 2 Z9 2 U1 0 U2 0 PU OXFORD UNIV PRESS UNITED KINGDOM PI OXFORD PA WALTON ST JOURNALS DEPT, OXFORD, ENGLAND OX2 6DP SN 0300-5771 J9 INT J EPIDEMIOL JI Int. J. Epidemiol. PD DEC PY 1990 VL 19 IS 4 BP 1066 EP 1071 DI 10.1093/ije/19.4.1066 PG 6 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA ET595 UT WOS:A1990ET59500043 PM 2083991 ER PT J AU THACKER, SB STROUP, DF AF THACKER, SB STROUP, DF TI PERSISTENCE OF INFLUENZA-A BY CONTINUOUS CLOSE-CONTACT TRANSMISSION - THE EFFECT OF NONRANDOM MIXING SO INTERNATIONAL JOURNAL OF EPIDEMIOLOGY LA English DT Article ID GLOBAL SPREAD; POPULATIONS; VIRUSES AB The interaction of two populations has variable effects on the nature and duration of epidemic activity, depending on the transmissibility of the virus, the susceptibility of the population, migration, birth and death rates, and the initial number of cases. Under circumstances where transmission stops in a single population (the infectious contact number is less than or equal to one), transmission may continue indefinitely when two populations interact under many different parameter combinations. A mass-action model was constructed using difference equations for two populations that included parameters for migration between populations and variable transmissibility between and within these populations. The limitations of extrapolating the model to actual conditions in human populations result from assumptions inherent in these models, such as fractional infection of individuals. RP THACKER, SB (reprint author), CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,MAIL STOP C08,ATLANTA,GA 30333, USA. NR 14 TC 4 Z9 4 U1 0 U2 4 PU OXFORD UNIV PRESS UNITED KINGDOM PI OXFORD PA WALTON ST JOURNALS DEPT, OXFORD, ENGLAND OX2 6DP SN 0300-5771 J9 INT J EPIDEMIOL JI Int. J. Epidemiol. PD DEC PY 1990 VL 19 IS 4 BP 1078 EP 1082 DI 10.1093/ije/19.4.1078 PG 5 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA ET595 UT WOS:A1990ET59500045 PM 2083993 ER PT J AU LANATA, CF STROH, G BLACK, RE GONZALES, H AF LANATA, CF STROH, G BLACK, RE GONZALES, H TI AN EVALUATION OF LOT QUALITY ASSURANCE SAMPLING TO MONITOR AND IMPROVE IMMUNIZATION COVERAGE SO INTERNATIONAL JOURNAL OF EPIDEMIOLOGY LA English DT Article AB Quality assurance sampling techniques with small samples offer a method of monitoring performance of health services in small health areas, and of identifying areas with poor performance in which remedial actions need to be targetted. Lot Quality Assurance Sampling methods were used to assess the coverage resulting from three immunization campaigns in rural and urban areas in the mountains of Peru. Application of these methods in 12 health areas with populations of 538 to 15 780 by Ministry of Health personnel proved feasible and could be used to identify areas with poorer vaccination coverage. Further discussion about possible reasons for poor coverage led to corrective actions in these health areas and an improvement in overall coverage from 78% to 88% in a three-month period. These quality assurance methods are a useful supervisory tool to improve health programme performance. C1 CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,DIV FIELD SERV,ATLANTA,GA 30333. JOHNS HOPKINS UNIV,SCH HYG & PUBL HLTH,DEPT INT HLTH,BALTIMORE,MD 21218. RP LANATA, CF (reprint author), INST INVEST NUTR,DIV RES,AP 18-0191,LIMA 18,PERU. OI Black, Robert/0000-0001-9926-7984 NR 5 TC 30 Z9 30 U1 0 U2 1 PU OXFORD UNIV PRESS UNITED KINGDOM PI OXFORD PA WALTON ST JOURNALS DEPT, OXFORD, ENGLAND OX2 6DP SN 0300-5771 J9 INT J EPIDEMIOL JI Int. J. Epidemiol. PD DEC PY 1990 VL 19 IS 4 BP 1086 EP 1090 DI 10.1093/ije/19.4.1086 PG 5 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA ET595 UT WOS:A1990ET59500047 PM 2083994 ER PT J AU KAHN, HS WILLIAMSON, DF AF KAHN, HS WILLIAMSON, DF TI THE CONTRIBUTIONS OF INCOME, EDUCATION AND CHANGING MARITAL-STATUS TO WEIGHT CHANGE AMONG US MEN SO INTERNATIONAL JOURNAL OF OBESITY LA English DT Article DE BODY WEIGHT; SOCIOECONOMIC FACTORS; INCOME; EDUCATIONAL STATUS; MARRIAGE ID BODY-MASS INDEX; RISK FACTOR CHANGE; YOUNG-ADULTS; DISEASE RISK; PATTERNS; FOLLOW AB The prevalence of overweight in men varies with socioeconomic and marital status. To explore the origin of these associations, we studied the effects of family income, education, and changing marital status on change in body mass index (BMI, kg/m2) over 10 years in a representative sample of US men. The subjects were 1552 white and black US men who entered the Health and Nutrition Examination Survey-I (in 1971-75) at ages 25-44 and were re-evaluated a decade later (in 1982-84). After adjusting for socio-demographic factors, baseline BMI, smoking and physical activity, the mean 10-year change in BMI was greater for men with 12 years of education (difference = 0.31 BMI units (95 percent CI 0.04-0.59)) or with < 12 years (difference 0.58 (0.22-0.94)) compared with men who studied beyond 12th grade. Ten-year weight changes were also defined categorically as major weight gain (BMI change greater-than-or-equal-to +4 units) or major weight loss (BMI change less-than-or-equal-to -2 units). By multiple logistic regression analysis, the odds of experiencing major weight gain were independently associated with low family income (odds ratio (OR) = 1.8 (95 percent CI, 1.0-3.3)) compared with favorable income, and with becoming married (OR = 3.3 (1.7-6.3)) or remaining unmarried (OR = 2.1 (1.1-4.2)) compared with men who were consistently married. The risk of major weight loss was independently associated with marriage ending (OR = 1.8 (1.0-3.3)) or with remaining unmarried (OR = 2.5 (1.3-4.7)). A US public health strategy for the prevention of men's weight gain should focus on men with little education or low family incomes and those who are unmarried. There may also be a benefit to preventive weight-gain counseling for men as they enter marriage. C1 CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV NUTR,MAIL STOP A41,ATLANTA,GA 30333. EMORY UNIV,SCH MED,DEPT COMMUNITY & PREVENT MED,ATLANTA,GA 30322. OI Kahn, Henry/0000-0003-2533-1562 NR 22 TC 45 Z9 45 U1 1 U2 4 PU STOCKTON PRESS PI BASINGSTOKE PA HOUNDMILLS, BASINGSTOKE, HAMPSHIRE, ENGLAND RG21 6XS SN 0307-0565 J9 INT J OBESITY JI Int. J. Obes. PD DEC PY 1990 VL 14 IS 12 BP 1057 EP 1068 PG 12 WC Endocrinology & Metabolism; Nutrition & Dietetics SC Endocrinology & Metabolism; Nutrition & Dietetics GA EU046 UT WOS:A1990EU04600008 PM 2086497 ER PT J AU TOOLE, MJ WALDMAN, RJ AF TOOLE, MJ WALDMAN, RJ TI HEALTH-PROBLEMS IN DEVELOPING-COUNTRIES - AN OVERVIEW SO INTERNATIONAL OPHTHALMOLOGY CLINICS LA English DT Article RP TOOLE, MJ (reprint author), CTR DIS CONTROL,INT HLTH PROGRAM OFF,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 0 TC 1 Z9 1 U1 0 U2 0 PU LITTLE BROWN CO PI BOSTON PA 34 BEACON STREET, BOSTON, MA 02108-1493 SN 0020-8167 J9 INT OPHTHALMOL CLIN JI Int. Ophthalmol. Clin. PD WIN PY 1990 VL 30 IS 1 BP 2 EP 6 DI 10.1097/00004397-199030010-00002 PG 5 WC Ophthalmology SC Ophthalmology GA CT286 UT WOS:A1990CT28600002 PM 2404884 ER PT J AU TOOLE, MJ WALDMAN, RJ AF TOOLE, MJ WALDMAN, RJ TI PRIORITY HEALTH INTERVENTIONS IN DEVELOPING-COUNTRIES SO INTERNATIONAL OPHTHALMOLOGY CLINICS LA English DT Article RP TOOLE, MJ (reprint author), CTR DIS CONTROL,INT HLTH PROGRAM OFF,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 0 TC 1 Z9 1 U1 0 U2 0 PU LITTLE BROWN CO PI BOSTON PA 34 BEACON STREET, BOSTON, MA 02108-1493 SN 0020-8167 J9 INT OPHTHALMOL CLIN JI Int. Ophthalmol. Clin. PD WIN PY 1990 VL 30 IS 1 BP 7 EP 11 DI 10.1097/00004397-199030010-00003 PG 5 WC Ophthalmology SC Ophthalmology GA CT286 UT WOS:A1990CT28600003 PM 2404896 ER PT J AU GRANT, PE BRENNER, DJ STEIGERWALT, AG HOLLIS, DG WEAVER, RE AF GRANT, PE BRENNER, DJ STEIGERWALT, AG HOLLIS, DG WEAVER, RE TI NEISSERIA-ELONGATA SUBSP NITROREDUCENS SUBSP-NOV, FORMERLY CDC GROUP M-6, A GRAM-NEGATIVE BACTERIUM ASSOCIATED WITH ENDOCARDITIS SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,MOREHOUSE SCH MED,ATLANTA,GA 30333. CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,MENINGITIS & SPECIAL PATHOGENS BRANCH,ATLANTA,GA 30333. NR 9 TC 30 Z9 30 U1 0 U2 1 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD DEC PY 1990 VL 28 IS 12 BP 2591 EP 2596 PG 6 WC Microbiology SC Microbiology GA EJ459 UT WOS:A1990EJ45900002 PM 2279987 ER PT J AU WALLACE, RJ TSUKAMURA, M BROWN, BA BROWN, J STEINGRUBE, VA ZHANG, Y NASH, DR AF WALLACE, RJ TSUKAMURA, M BROWN, BA BROWN, J STEINGRUBE, VA ZHANG, Y NASH, DR TI CEFOTAXIME-RESISTANT NOCARDIA-ASTEROIDES STRAINS ARE ISOLATES OF THE CONTROVERSIAL SPECIES NOCARDIA-FARCINICA SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article C1 NATL CHUBU HOSP,OBU AICHI,JAPAN. CTR DIS CONTROL,CTR INFECT DIS,DIV MYCOT DIS,ATLANTA,GA 30333. RP WALLACE, RJ (reprint author), UNIV TEXAS,CTR HLTH,DEPT MICROBIOL,TYLER,TX 75710, USA. NR 29 TC 141 Z9 142 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD DEC PY 1990 VL 28 IS 12 BP 2726 EP 2732 PG 7 WC Microbiology SC Microbiology GA EJ459 UT WOS:A1990EJ45900026 PM 2280003 ER PT J AU ERDMAN, DD ANDERSON, LJ AF ERDMAN, DD ANDERSON, LJ TI MONOCLONAL ANTIBODY-BASED CAPTURE ENZYME IMMUNOASSAYS FOR SPECIFIC SERUM IMMUNOGLOBULIN-G (IGG), IGA, AND IGM ANTIBODIES TO RESPIRATORY SYNCYTIAL VIRUS SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article RP ERDMAN, DD (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,ATLANTA,GA 30333, USA. NR 26 TC 21 Z9 21 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD DEC PY 1990 VL 28 IS 12 BP 2744 EP 2749 PG 6 WC Microbiology SC Microbiology GA EJ459 UT WOS:A1990EJ45900029 PM 2280004 ER PT J AU VISVESVARA, GS MARTINEZ, AJ SCHUSTER, FL LEITCH, GJ WALLACE, SV SAWYER, TK ANDERSON, M AF VISVESVARA, GS MARTINEZ, AJ SCHUSTER, FL LEITCH, GJ WALLACE, SV SAWYER, TK ANDERSON, M TI LEPTOMYXID-AMEBA, A NEW AGENT OF AMEBIC MENINGOENCEPHALITIS IN HUMANS AND ANIMALS SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article C1 MOREHOUSE SCH MED,ATLANTA,GA 30314. RESCON ASSOCIATES,OXFORD,MD 21662. SAN DIEGO ZOO,SAN DIEGO,CA 92112. UNIV PITTSBURGH,SCH MED,PITTSBURGH,PA 15260. CUNY,BROOKLYN COLL,NEW YORK,NY 10021. RP VISVESVARA, GS (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 30 TC 166 Z9 172 U1 0 U2 3 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD DEC PY 1990 VL 28 IS 12 BP 2750 EP 2756 PG 7 WC Microbiology SC Microbiology GA EJ459 UT WOS:A1990EJ45900030 PM 2280005 ER PT J AU TOKARS, JI MCNEIL, MM TABLAN, OC CHAPINROBERTSON, K PATTERSON, JE EDBERG, SC JARVIS, WR AF TOKARS, JI MCNEIL, MM TABLAN, OC CHAPINROBERTSON, K PATTERSON, JE EDBERG, SC JARVIS, WR TI MYCOBACTERIUM-GORDONAE PSEUDOINFECTION ASSOCIATED WITH A CONTAMINATED ANTIMICROBIAL SOLUTION SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL & MYCOT DIS,ATLANTA,GA 30333. YALE UNIV,SCH MED,DEPT MED,NEW HAVEN,CT 06504. YALE UNIV,SCH MED,DEPT LAB MED,NEW HAVEN,CT 06504. RP TOKARS, JI (reprint author), CTR DIS CONTROL,CTR INFECT DIS,HOSP INFECT PROGRAM,ATLANTA,GA 30333, USA. NR 22 TC 38 Z9 38 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD DEC PY 1990 VL 28 IS 12 BP 2765 EP 2769 PG 5 WC Microbiology SC Microbiology GA EJ459 UT WOS:A1990EJ45900033 PM 2280008 ER PT J AU WENGER, JD SWAMINATHAN, B HAYES, PS GREEN, SS PRATT, M PINNER, RW SCHUCHAT, A BROOME, CV AF WENGER, JD SWAMINATHAN, B HAYES, PS GREEN, SS PRATT, M PINNER, RW SCHUCHAT, A BROOME, CV TI LISTERIA-MONOCYTOGENES CONTAMINATION OF TURKEY FRANKS - EVALUATION OF A PRODUCTION FACILITY SO JOURNAL OF FOOD PROTECTION LA English DT Article C1 USDA,FOOD SAFETY & INSPECT SERV,WASHINGTON,DC 20250. USDA,FOOD SAFETY & INSPECT SERV,MIDWESTERN LAB,ST LOUIS,MO 63120. RP WENGER, JD (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,MENINGITIS & SPECIAL PATHOGENS BRANCH,ATLANTA,GA 30333, USA. NR 29 TC 91 Z9 92 U1 1 U2 7 PU INT ASSOC MILK FOOD ENVIRONMENTAL SANITARIANS, INC PI DES MOINES PA 6200 AURORA AVE SUITE 200W, DES MOINES, IA 50322-2838 SN 0362-028X J9 J FOOD PROTECT JI J. Food Prot. PD DEC PY 1990 VL 53 IS 12 BP 1015 EP 1019 PG 5 WC Biotechnology & Applied Microbiology; Food Science & Technology SC Biotechnology & Applied Microbiology; Food Science & Technology GA EN417 UT WOS:A1990EN41700003 ER PT J AU SPEAR, GT OU, CY KESSLER, HA MOORE, JL SCHOCHETMAN, G LANDAY, AL AF SPEAR, GT OU, CY KESSLER, HA MOORE, JL SCHOCHETMAN, G LANDAY, AL TI ANALYSIS OF LYMPHOCYTES, MONOCYTES, AND NEUTROPHILS FROM HUMAN-IMMUNODEFICIENCY-VIRUS (HIV)-INFECTED PERSONS FOR HIV DNA SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,ATLANTA,GA 30333. RUSH PRESBYTERIAN ST LUKES MED CTR,DEPT MED,CHICAGO,IL 60612. RP SPEAR, GT (reprint author), RUSH PRESBYTERIAN ST LUKES MED CTR,DEPT IMMUNOL MICROBIOL,CHICAGO,IL 60612, USA. FU NIAID NIH HHS [AI-25915] NR 31 TC 70 Z9 70 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD DEC PY 1990 VL 162 IS 6 BP 1239 EP 1244 PG 6 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EK574 UT WOS:A1990EK57400003 PM 1977808 ER PT J AU HALL, CB WALSH, EE SCHNABEL, KC LONG, CE MCCONNOCHIE, KM HILDRETH, SW ANDERSON, LJ AF HALL, CB WALSH, EE SCHNABEL, KC LONG, CE MCCONNOCHIE, KM HILDRETH, SW ANDERSON, LJ TI OCCURRENCE OF GROUP-A AND GROUP-B OF RESPIRATORY SYNCYTIAL VIRUS OVER 15 YEARS - ASSOCIATED EPIDEMIOLOGIC AND CLINICAL CHARACTERISTICS IN HOSPITALIZED AND AMBULATORY CHILDREN SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article C1 PRAXIS BIOL,ROCHESTER,NY. CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL DIS,ATLANTA,GA 30333. UNIV ROCHESTER,SCH MED & DENT,DEPT MED,ROCHESTER,NY 14642. RP HALL, CB (reprint author), UNIV ROCHESTER,SCH MED & DENT,DEPT PEDIAT,BOX 689,601 ELMWOOD AVE,ROCHESTER,NY 14642, USA. FU NIAID NIH HHS [AI-05049, AI-20608] NR 23 TC 191 Z9 206 U1 0 U2 1 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD DEC PY 1990 VL 162 IS 6 BP 1283 EP 1290 PG 8 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EK574 UT WOS:A1990EK57400009 PM 2230258 ER PT J AU WENGER, JD HIGHTOWER, AW FACKLAM, RR GAVENTA, S BROOME, CV AF WENGER, JD HIGHTOWER, AW FACKLAM, RR GAVENTA, S BROOME, CV TI BACTERIAL-MENINGITIS IN THE UNITED-STATES, 1986 - REPORT OF A MULTISTATE SURVEILLANCE STUDY SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article C1 CTR DIS CONTROL,RESP & SPECIAL PATHOGENS BRANCH,ATLANTA,GA 30333. CTR DIS CONTROL,CTR INFECT DIS,STAT SERV ACTIV,DIV BACTERIAL DIS,ATLANTA,GA 30333. RP WENGER, JD (reprint author), CTR DIS CONTROL,CTR INFECT DIS,MENINGITIS & SPECIAL PATHOGENS BRANCH,BLDG 1,ROOM 5409,CO9,ATLANTA,GA 30333, USA. NR 10 TC 310 Z9 315 U1 0 U2 5 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD DEC PY 1990 VL 162 IS 6 BP 1316 EP 1323 PG 8 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EK574 UT WOS:A1990EK57400014 PM 2230261 ER PT J AU WHARTON, M SPIEGEL, RA HORAN, JM TAUXE, RV WELLS, JG BARG, N HERNDON, J MERIWETHER, RA MACCORMACK, JN LEVINE, RH AF WHARTON, M SPIEGEL, RA HORAN, JM TAUXE, RV WELLS, JG BARG, N HERNDON, J MERIWETHER, RA MACCORMACK, JN LEVINE, RH TI A LARGE OUTBREAK OF ANTIBIOTIC-RESISTANT SHIGELLOSIS AT A MASS GATHERING SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article C1 CTR DIS CONTROL,DIV FIELD SERV,EPIDEMIOL PROGRAM OFF,ATLANTA,GA 30333. VANDERBILT UNIV,MED CTR,SCH MED,NASHVILLE,TN 37232. N CAROLINA DIV HLTH SERV,RALEIGH,NC. NR 19 TC 43 Z9 46 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD DEC PY 1990 VL 162 IS 6 BP 1324 EP 1328 PG 5 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EK574 UT WOS:A1990EK57400015 PM 2230262 ER PT J AU SCHANTZ, PM BRANDT, FH DICKINSON, CM ALLEN, CR ROBERTS, JM EBERHARD, ML AF SCHANTZ, PM BRANDT, FH DICKINSON, CM ALLEN, CR ROBERTS, JM EBERHARD, ML TI EFFECTS OF ALBENDAZOLE ON ECHINOCOCCUS-MULTILOCULARIS INFECTION IN THE MONGOLIAN JIRD SO JOURNAL OF INFECTIOUS DISEASES LA English DT Note RP SCHANTZ, PM (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,MAIL STOP F13,ATLANTA,GA 30333, USA. NR 17 TC 18 Z9 19 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD DEC PY 1990 VL 162 IS 6 BP 1403 EP 1407 PG 5 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EK574 UT WOS:A1990EK57400032 PM 2230275 ER PT J AU BENNION, SD FERRIS, C LIEU, TS REIMER, CB LEE, LA AF BENNION, SD FERRIS, C LIEU, TS REIMER, CB LEE, LA TI IGG SUBCLASSES IN THE SERUM AND SKIN IN SUBACUTE CUTANEOUS LUPUS-ERYTHEMATOSUS AND NEONATAL LUPUS-ERYTHEMATOSUS SO JOURNAL OF INVESTIGATIVE DERMATOLOGY LA English DT Article ID ANTIBODY; FETAL; DISEASE; ANTIGEN; MARKER; HEALTH; MICE AB IgG subclasses differ in their biologic and chemical properties, such as complement fixation, protein and cellular binding, and placental transfer. In this study, IgG subclasses of anti-Ro/SSA antibodies in subacute cutaneous lupus (SCLE) and neonatal lupus (NLE) are examined in the serum and in the skin. IgG subclasses in NLE beginning in utero (NLE-heart disease) are compared to subclasses in NLE beginning after birth (NLE-skin disease). Human skin was grafted onto athymic mice, mice were injected with one of eight anti-Ro/SSA maternal NLE sera (four heart block, four skin disease) or seven anti-Ro/SSA SCLE sera, and grafts were examined for IgG subclasses using monoclonal anti-human IgG subclass reagents in an immunofluorescent technique. Lesional skin was examined from four SCLE patients. IgG1 was the only IgG subclass detected in the grafts and skin lesions. IgG1 was the predominant anti-Ro/SSA IgG subclass detected in SCLE and NLE sera in an ELISA using a synthetic Ro/SSA polypeptide. These studies show that the maternal anti-Ro/SSA autoantibodies in NLE-heart disease sera are predominantly IgG1 and are therefore likely to be present in the fetus at the time of gestation, when heart block usually develops. Second, differences in the clinical presentations of NLE (in utero vs. postnatal disease) cannot be attributed to differences in anti-Ro/SSa IgG subclasses. Finally, the subclass bound in the skin in SCLE is IgG1, a subclass capable of mediating tissue injury via complement or cellular effectors. C1 DENVER VET ADM HOSP,DENVER,CO. FITZSIMONS ARMY MED CTR,DEPT ELECT ENGN,AURORA,CO 80045. UNIV TEXAS,HLTH SCI CTR,SW MED SCH,DEPT DERMATOL,DALLAS,TX 75235. CTR DIS CONTROL,CTR INFECT DIS,DIV HOST FACTORS,ATLANTA,GA 30333. UNIV COLORADO,SCH MED,DEPT DERMATOL,DENVER,CO 80202. UNIV COLORADO,SCH MED,DEPT MED,DENVER,CO 80202. RP BENNION, SD (reprint author), FITZSIMONS ARMY MED CTR,DERMATOL SERV,AURORA,CO 80045, USA. FU NIAMS NIH HHS [AR01487] NR 21 TC 24 Z9 25 U1 0 U2 0 PU BLACKWELL SCIENCE INC PI CAMBRIDGE PA 238 MAIN ST, CAMBRIDGE, MA 02142 SN 0022-202X J9 J INVEST DERMATOL JI J. Invest. Dermatol. PD DEC PY 1990 VL 95 IS 6 BP 643 EP 646 DI 10.1111/1523-1747.ep12514311 PG 4 WC Dermatology SC Dermatology GA EP025 UT WOS:A1990EP02500005 PM 2250107 ER PT J AU DICKERSON, JW EBERHARD, ML LAMMIE, PJ AF DICKERSON, JW EBERHARD, ML LAMMIE, PJ TI A TECHNIQUE FOR MICROFILARIAL DETECTION IN PRESERVED BLOOD USING NUCLEPORE FILTERS SO JOURNAL OF PARASITOLOGY LA English DT Article ID FILARIASIS AB Nuclepore filtration is now the most widely used method of detecting microfilaremia, particularly if microfilariae are few in number. However, this system requires the blood sample to be processed promptly after collection. Using blood from Wuchereria bancrofti-infected patients, 3 solutions were tested to determine whether blood could be held for delayed processing. Of these, we identified 1, 2% formalin/10% Teepol, in which microfilaremic blood can be held for at least 9 mo without deterioration of microfilarial structure or decrease in microfilarial numbers. In addition, this mixture passed easily through a 5-mu-m filter at all times tested. Examination of more than 300 blood samples held in 2% formalin/10% Teepol showed that this solution can utilize the convenience and sensitivity of membrane filtration while eliminating the need to perform testing immediately after the blood is collected. RP DICKERSON, JW (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,PARASIT DIS BRANCH,ATLANTA,GA 30333, USA. FU NIAID NIH HHS [AI 16315] NR 8 TC 11 Z9 11 U1 0 U2 2 PU AMER SOC PARASITOLOGISTS PI LAWRENCE PA 810 EAST 10TH STREET, LAWRENCE, KS 66044 SN 0022-3395 J9 J PARASITOL JI J. Parasitol. PD DEC PY 1990 VL 76 IS 6 BP 829 EP 833 DI 10.2307/3282801 PG 5 WC Parasitology SC Parasitology GA EP952 UT WOS:A1990EP95200010 PM 2123924 ER PT J AU MILLET, P COLLINS, WE MONKEN, CE BROWN, BG AF MILLET, P COLLINS, WE MONKEN, CE BROWN, BG TI INVITRO MATURATION OF THE EXOERYTHROCYTIC STAGE OF PLASMODIUM-KNOWLESI OBSERVED UNDER PHASE-CONTRAST MICROSCOPY SO JOURNAL OF PARASITOLOGY LA English DT Note AB Exoerythrocytic stages of Plasmodium knowlesi were obtained in primary culture of rhesus monkey hepatocytes. The development of a single parasite was followed with phase contrast microscopy until release of merozoites in slightly less than 5 days. This direct observation may offer opportunities to determine visually factors that may influence specific steps of schizont development. C1 CTR DIS CONTROL,CTR INFECT DIS,HEPATITIS BRANCH,ATLANTA,GA 30333. CTR DIS CONTROL,CTR INFECT DIS,OFF SCI SERV,ATLANTA,GA 30333. RP MILLET, P (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,MALARIA BRANCH,ATLANTA,GA 30333, USA. NR 5 TC 2 Z9 2 U1 0 U2 0 PU AMER SOC PARASITOLOGISTS PI LAWRENCE PA 810 EAST 10TH STREET, LAWRENCE, KS 66044 SN 0022-3395 J9 J PARASITOL JI J. Parasitol. PD DEC PY 1990 VL 76 IS 6 BP 923 EP 925 DI 10.2307/3282816 PG 3 WC Parasitology SC Parasitology GA EP952 UT WOS:A1990EP95200025 PM 2254828 ER PT J AU SZPUNAR, SM BURT, BA AF SZPUNAR, SM BURT, BA TI FLUORIDE EXPOSURE IN MICHIGAN SCHOOLCHILDREN SO JOURNAL OF PUBLIC HEALTH DENTISTRY LA English DT Article C1 UNIV MICHIGAN,SCH PUBL HLTH 2,PROGRAM DENT PUBL HLTH,ANN ARBOR,MI 48109. RP SZPUNAR, SM (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,DENT DIS PREVENT ACTIV,E09,ATLANTA,GA 30333, USA. FU NIDCR NIH HHS [DE 07157] NR 23 TC 25 Z9 25 U1 0 U2 2 PU AAPHD NATIONAL OFFICE PI RICHMOND PA J PUBLIC HEALTH DENT 10619 JOUSTING LANE, RICHMOND, VA 23235 SN 0022-4006 J9 J PUBLIC HEALTH DENT JI J. Public Health Dent. PD WIN PY 1990 VL 50 IS 1 BP 18 EP 23 DI 10.1111/j.1752-7325.1990.tb03552.x PG 6 WC Dentistry, Oral Surgery & Medicine; Public, Environmental & Occupational Health SC Dentistry, Oral Surgery & Medicine; Public, Environmental & Occupational Health GA CH998 UT WOS:A1990CH99800004 PM 2295998 ER PT J AU MALVITZ, DM AF MALVITZ, DM TI CONFERENCE ON MEASURING THE IMPACT OF PUBLIC-LAW 99-252 - INTRODUCTION SO JOURNAL OF PUBLIC HEALTH DENTISTRY LA English DT Article; Proceedings Paper CT CONF ON MULTIDISCIPLINARY INDICATIONS TO MEASURE THE IMPACT OF PUBLIC LAW 99-252 ON DECREASING SMOKELESS TOBACCO USE CY JAN 29-30, 1988 CL COLUMBUS, OH RP MALVITZ, DM (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,DENT DIS PREVENT ACTIV,ATLANTA,GA 30333, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AAPHD NATIONAL OFFICE PI RICHMOND PA J PUBLIC HEALTH DENT 10619 JOUSTING LANE, RICHMOND, VA 23235 SN 0022-4006 J9 J PUBLIC HEALTH DENT JI J. Public Health Dent. PD WIN PY 1990 VL 50 IS 1 BP 64 EP 64 DI 10.1111/j.1752-7325.1990.tb03559.x PG 1 WC Dentistry, Oral Surgery & Medicine; Public, Environmental & Occupational Health SC Dentistry, Oral Surgery & Medicine; Public, Environmental & Occupational Health GA CH998 UT WOS:A1990CH99800010 ER PT J AU BARFUSS, DW ROBINSON, MK ZALUPS, RK AF BARFUSS, DW ROBINSON, MK ZALUPS, RK TI INORGANIC MERCURY TRANSPORT IN THE PROXIMAL TUBULE OF THE RABBIT SO JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY LA English DT Article DE MERCURY; KIDNEY; PROXIMAL TUBULE; RABBIT; NEPHROTOXICITY ID SILVER AMPLIFICATION METHOD; UNILATERAL NEPHRECTOMY; CHLORIDE; NEPHROTOXICITY; ABSORPTION; INJECTION; RAT AB Inorganic mercury transport was studied in the S1, S2, and S3 segments of the isolated perfused proximal tubule of the rabbit. The concentration of mercury in the perfusate was 18.4-mu-M. At this concentration all three segments of the proximal tubule underwent degenerative changes that proceeded to cellular necrosis at the end of the tubule which was attached to the perfusion pipet. This pathological process progressed along the tubule for approximately 200-mu-m. The remainder of the tubule, to the collection pipette, remained intact and free of any pathological changes. In examining the transport of mercury under these conditions, it was found that, on average, the S1, S2, and S3 segments all removed inorganic mercury from the luminal fluid at approximately 140 fmol min-1 mm-1. The transport of mercury, as measured by the appearance of Hg-203 in the bathing solution, was 80% lower than the removal of Hg-203 from the luminal fluid. The mercury appearing in the bath could be accounted for by passive leakage through the necrotic portion of the tubule in the S1 and S2 segments, but not in the S3 segment. Leakage could account for only 16.2% of the transepithelial movement of inorganic mercury in the S3 segment. Inorganic mercury taken up by the tubule (92%) was primarily associated with the structural proteins of the tubular epithelial cells, while very little (8%) was found in the tubular extract. The toxicity of inorganic mercury was determined by titration. Perfusion with 1-mu-M inorganic mercury produced necrosis. The pathological features appeared to be the same as those resulting with 18.5-mu-M inorganic mercury. When a tubule was perfused with 100 nM inorganic mercury, slight cellular swelling occurred for the first 50-mu-m of the tubule, while perfusion with 10 nM inorganic mercury caused no apparent pathology. In contrast, 184-mu-M inorganic mercury caused total and rapid necrosis of the entire perfused nephron segment. It was concluded that inorganic mercury is avidly removed from the luminal fluid by all regions of the proximal tubule. However, substantial transepithelial transport of inorganic mercury occurs in the S3 segment only. C1 GEORGIA STATE UNIV,DEPT BIOL,ATLANTA,GA 30303. CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV ENVIRONM HLTH LAB SCI,ATLANTA,GA 30333. MERCER UNIV,SCH MED,DIV BASIC MED SCI,MACON,GA 31207. FU NIEHS NIH HHS [ES 05157] NR 18 TC 19 Z9 19 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 1046-6673 J9 J AM SOC NEPHROL JI J. Am. Soc. Nephrol. PD DEC PY 1990 VL 1 IS 6 BP 910 EP 917 PG 8 WC Urology & Nephrology SC Urology & Nephrology GA FT102 UT WOS:A1990FT10200008 PM 2103850 ER PT J AU ZAKI, SR AUSTIN, GE SWAN, DC HOOPER, WC GREER, PW EVATT, BL CHAN, WC AF ZAKI, SR AUSTIN, GE SWAN, DC HOOPER, WC GREER, PW EVATT, BL CHAN, WC TI STUDIES OF MYELOPEROXIDASE GENE-EXPRESSION AT THE CELLULAR-LEVEL BY INSITU HYBRIDIZATION SO LEUKEMIA LA English DT Article ID HUMAN EOSINOPHIL PEROXIDASE; ACUTE MYELOGENOUS LEUKEMIA; INFANT ACUTE-LEUKEMIA; MONOCLONAL-ANTIBODIES; GENOTYPIC HETEROGENEITY; MOLECULAR-CLONING; MYELOID LEUKEMIAS; MESSENGER-RNA; HL-60 CELLS; DIFFERENTIATION AB Recent studies have demonstrated myeloperoxidase (MPO) gene expression during granulocytic differentiation. Since these studies have been done exclusively by Northern and dot blot analysis and frequently with mixed populations of cells, quantitative changes in gene expression for particular populations of cells are difficult to assess. We therefore examined MPO expression at the cellular level in various normal and malignant hematopoietic cells by the in situ hybridization (ISH) technique. Using this approach, we demonstrated that inducing the promyelocytic HL-60 cells line to differentiate along either monocytic or granulocytic pathways decreases MPO mRNA expression. Similarly, when ISH was performed on normal bone marrow, relatively high levels of MPO mRNA were detected in myeloblasts, promyelocytes, and early eosinophilic precursors, whereas the expression was markedly decreased in more advanced stages of myeloid differentiation. These findings agree with the known decrease in MPO protein synthesis observed during granulocytic differentiation and suggest that regulation of MPO protein synthesis occurs at the level of MPO mRNA expression. We conclude by showing that ISH can detect MPO mRNA in myeloblasts of patients with acute leukemia and can be a potentially useful technique in the study of myeloid differentiation in acute leukemias. C1 EMORY UNIV,SCH MED,DEPT PATHOL,ATLANTA,GA 30322. VET ADM MED CTR,ATLANTA,GA. RP ZAKI, SR (reprint author), CTR DIS CONTROL,DIV IMMUNOL ONCOL & HEMATOL DIS,EXPTL PATHOL BRANCH,ATLANTA,GA 30333, USA. NR 42 TC 27 Z9 27 U1 0 U2 1 PU STOCKTON PRESS PI BASINGSTOKE PA HOUNDMILLS, BASINGSTOKE, HAMPSHIRE, ENGLAND RG21 6XS SN 0887-6924 J9 LEUKEMIA JI Leukemia PD DEC PY 1990 VL 4 IS 12 BP 813 EP 818 PG 6 WC Oncology; Hematology SC Oncology; Hematology GA EQ200 UT WOS:A1990EQ20000005 PM 2173803 ER PT J AU ATRASH, HK KOONIN, LM LAWSON, HW FRANKS, AL SMITH, JC AF ATRASH, HK KOONIN, LM LAWSON, HW FRANKS, AL SMITH, JC TI MATERNAL MORTALITY IN THE UNITED-STATES, 1979-1986 SO OBSTETRICS AND GYNECOLOGY LA English DT Article RP ATRASH, HK (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV REPROD HLTH,MAILSTOP C-06,ATLANTA,GA 30333, USA. NR 23 TC 115 Z9 118 U1 0 U2 1 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0029-7844 J9 OBSTET GYNECOL JI Obstet. Gynecol. PD DEC PY 1990 VL 76 IS 6 BP 1055 EP 1060 PG 6 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA EK058 UT WOS:A1990EK05800013 PM 2234713 ER PT J AU PETERSON, HB LEE, NC AF PETERSON, HB LEE, NC TI LONG-TERM HEALTH RISKS AND BENEFITS OF ORAL-CONTRACEPTIVE USE SO OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA LA English DT Article ID INVASIVE CERVICAL-CANCER; BREAST-CANCER; CARDIOVASCULAR-DISEASE; MYOCARDIAL-INFARCTION; NULLIPAROUS WOMEN; YOUNG-WOMEN; AGE; CARCINOMA; PREGNANCY; CROSSOVER RP PETERSON, HB (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV REPROD HLTH,ATLANTA,GA 30333, USA. NR 50 TC 3 Z9 3 U1 0 U2 0 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0889-8545 J9 OBSTET GYN CLIN N AM JI Obstet. Gynecol. Clin. N. Am. PD DEC PY 1990 VL 17 IS 4 BP 775 EP 788 PG 14 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA EP775 UT WOS:A1990EP77500007 PM 2092241 ER PT J AU STONE, KM AF STONE, KM TI AVOIDING SEXUALLY-TRANSMITTED DISEASES SO OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA LA English DT Article ID HUMAN IMMUNODEFICIENCY VIRUS; CHLAMYDIA-TRACHOMATIS; HOMOSEXUAL MEN; UNITED-STATES; CERVICAL-CANCER; CLINICAL-TRIAL; HIV INFECTION; CONDOM USE; TRANSMISSION; GONORRHEA RP STONE, KM (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,TECH INFORMAT SERV,DIV STD HIV PREVENT,MAIL STOP E06,ATLANTA,GA 30333, USA. NR 74 TC 11 Z9 11 U1 0 U2 2 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0889-8545 J9 OBSTET GYN CLIN N AM JI Obstet. Gynecol. Clin. N. Am. PD DEC PY 1990 VL 17 IS 4 BP 789 EP 799 PG 11 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA EP775 UT WOS:A1990EP77500008 PM 2092242 ER PT J AU HINMAN, AR AF HINMAN, AR TI IMMUNIZATIONS IN THE UNITED-STATES SO PEDIATRICS LA English DT Article RP HINMAN, AR (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,ATLANTA,GA 30333, USA. NR 10 TC 19 Z9 19 U1 0 U2 0 PU AMER ACAD PEDIATRICS PI ELK GROVE VILLAGE PA 141 NORTH-WEST POINT BLVD, ELK GROVE VILLAGE, IL 60007-1098 SN 0031-4005 J9 PEDIATRICS JI Pediatrics PD DEC PY 1990 VL 86 IS 6 SU S BP 1064 EP 1066 PG 3 WC Pediatrics SC Pediatrics GA EM228 UT WOS:A1990EM22800010 PM 2243741 ER PT J AU ROSENBERG, ML RODRIGUEZ, JG CHORBA, TL AF ROSENBERG, ML RODRIGUEZ, JG CHORBA, TL TI CHILDHOOD INJURIES - WHERE WE ARE SO PEDIATRICS LA English DT Article RP ROSENBERG, ML (reprint author), US DEPT HHS,CTR ENVIRONM HLTH & INJURY CONTROL,DIV INJURY CONTROL,ATLANTA,GA 30333, USA. NR 14 TC 15 Z9 16 U1 0 U2 0 PU AMER ACAD PEDIATRICS PI ELK GROVE VILLAGE PA 141 NORTH-WEST POINT BLVD, ELK GROVE VILLAGE, IL 60007-1098 SN 0031-4005 J9 PEDIATRICS JI Pediatrics PD DEC PY 1990 VL 86 IS 6 SU S BP 1084 EP 1091 PG 8 WC Pediatrics SC Pediatrics GA EM228 UT WOS:A1990EM22800015 PM 2243745 ER PT J AU MARKOVITZ, DM HANNIBAL, M PEREZ, VL GAUNTT, C FOLKS, TM NABEL, GJ AF MARKOVITZ, DM HANNIBAL, M PEREZ, VL GAUNTT, C FOLKS, TM NABEL, GJ TI DIFFERENTIAL REGULATION OF HUMAN IMMUNODEFICIENCY VIRUSES (HIV) - A SPECIFIC REGULATORY ELEMENT IN HIV-2 RESPONDS TO STIMULATION OF THE T-CELL ANTIGEN RECEPTOR SO PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA LA English DT Article C1 UNIV MICHIGAN,MED CTR,DEPT INTERNAL MED,HOWARD HUGHES MED INST,ANN ARBOR,MI 48109. UNIV MICHIGAN,MED CTR,DEPT BIOL CHEM,ANN ARBOR,MI 48109. CTR DIS CONTROL,RETROVIRUS DIS BRANCH,ATLANTA,GA 30333. FU NIAID NIH HHS [AI26865, AI29179] NR 54 TC 56 Z9 56 U1 0 U2 0 PU NATL ACAD SCIENCES PI WASHINGTON PA 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 SN 0027-8424 J9 P NATL ACAD SCI USA JI Proc. Natl. Acad. Sci. U. S. A. PD DEC PY 1990 VL 87 IS 23 BP 9098 EP 9102 DI 10.1073/pnas.87.23.9098 PG 5 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA EL366 UT WOS:A1990EL36600006 PM 2147512 ER PT J AU GAYLE, HD KEELING, RP GARCIATUNON, M KILBOURNE, BW NARKUNAS, JP INGRAM, FR ROGERS, MF CURRAN, JW AF GAYLE, HD KEELING, RP GARCIATUNON, M KILBOURNE, BW NARKUNAS, JP INGRAM, FR ROGERS, MF CURRAN, JW TI PREVALENCE OF THE HUMAN-IMMUNODEFICIENCY-VIRUS AMONG UNIVERSITY-STUDENTS SO NEW ENGLAND JOURNAL OF MEDICINE LA English DT Article C1 AMER COLL HLTH ASSOC,ROCKVILLE,MD. UNIV VIRGINIA,MED CTR,SCH MED,DEPT INTERNAL MED,CHARLOTTESVILLE,VA 22901. UNIV VIRGINIA,MED CTR,SCH MED,DEPT STUDENT HLTH,CHARLOTTESVILLE,VA 22901. RP GAYLE, HD (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS MSE50,ATLANTA,GA 30333, USA. NR 29 TC 131 Z9 132 U1 1 U2 2 PU MASS MEDICAL SOC PI BOSTON PA 10 SHATTUCK, BOSTON, MA 02115 SN 0028-4793 J9 NEW ENGL J MED JI N. Engl. J. Med. PD NOV 29 PY 1990 VL 323 IS 22 BP 1538 EP 1541 DI 10.1056/NEJM199011293232206 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA EK209 UT WOS:A1990EK20900006 PM 2233933 ER PT J AU ZINGESER, JA BIRKHEAD, GS MAMOLEN, M VOGT, RL AF ZINGESER, JA BIRKHEAD, GS MAMOLEN, M VOGT, RL TI AIR SAMPLING FOR LEGIONELLA SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Letter C1 NEW YORK STATE DEPT HLTH,ALBANY,NY 12201. VERMONT DEPT HLTH,BURLINGTON,VT. RP ZINGESER, JA (reprint author), CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,ATLANTA,GA 30333, USA. NR 5 TC 4 Z9 5 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD NOV 28 PY 1990 VL 264 IS 20 BP 2625 EP 2626 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA EJ584 UT WOS:A1990EJ58400018 PM 2232037 ER PT J AU BREIMAN, RF FIELDS, BS SANDEN, GN BARBAREE, JM AF BREIMAN, RF FIELDS, BS SANDEN, GN BARBAREE, JM TI AIR SAMPLING FOR LEGIONELLA - REPLY SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Letter RP BREIMAN, RF (reprint author), CTR DIS CONTROL,RESP MED BRANCH,ATLANTA,GA 30333, USA. NR 5 TC 1 Z9 1 U1 1 U2 2 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD NOV 28 PY 1990 VL 264 IS 20 BP 2626 EP 2626 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EJ584 UT WOS:A1990EJ58400019 ER PT J AU HAHN, RA TEUTSCH, SM ROTHENBERG, RB MARKS, JS AF HAHN, RA TEUTSCH, SM ROTHENBERG, RB MARKS, JS TI EXCESS DEATHS FROM 9 CHRONIC DISEASES IN THE UNITED-STATES, 1986 SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,ATLANTA,GA 30333. RP HAHN, RA (reprint author), CTR DIS CONTROL,DIV SURVEILLANCE & EPIDEMIOL,EPIDEMIOL PROGRAM OFF,MAILSTOP G-34,ATLANTA,GA 30333, USA. NR 49 TC 101 Z9 102 U1 0 U2 1 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD NOV 28 PY 1990 VL 264 IS 20 BP 2654 EP 2659 DI 10.1001/jama.264.20.2654 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA EJ584 UT WOS:A1990EJ58400029 PM 2232042 ER PT J AU KENNEDY, ER OCONNOR, PF GROTE, AA AF KENNEDY, ER OCONNOR, PF GROTE, AA TI APPLICATION OF MULTIDIMENSIONAL GAS-CHROMATOGRAPHY MASS-SPECTROMETRY TO THE DETERMINATION OF GLYCOL ETHERS IN AIR SO JOURNAL OF CHROMATOGRAPHY LA English DT Article ID HYDROCARBONS C1 NIOSH,DIV PHYS SCI & ENGN,MEASUREMENTS RES SUPPORT BRANCH,CINCINNATI,OH 45226. RP KENNEDY, ER (reprint author), NIOSH,DIV PHYS SCI & ENGN,METHODS RES BRANCH,INORGAN METHODS DEV SECT,CINCINNATI,OH 45226, USA. NR 15 TC 10 Z9 11 U1 0 U2 3 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0021-9673 J9 J CHROMATOGR PD NOV 28 PY 1990 VL 522 BP 303 EP 313 DI 10.1016/0021-9673(90)85200-F PG 11 WC Chemistry, Analytical SC Chemistry GA EN441 UT WOS:A1990EN44100028 PM 2081755 ER PT J AU RUTHERFORD, GW LIFSON, AR HESSOL, NA DARROW, WW OMALLEY, PM BUCHBINDER, SP BARNHART, JL BODECKER, TW CANNON, L DOLL, LS HOLMBERG, SD HARRISON, JS ROGERS, MF WERDEGAR, D JAFFE, HW AF RUTHERFORD, GW LIFSON, AR HESSOL, NA DARROW, WW OMALLEY, PM BUCHBINDER, SP BARNHART, JL BODECKER, TW CANNON, L DOLL, LS HOLMBERG, SD HARRISON, JS ROGERS, MF WERDEGAR, D JAFFE, HW TI COURSE OF HIV-I INFECTION IN A COHORT OF HOMOSEXUAL AND BISEXUAL MEN - AN 11 YEAR FOLLOW-UP-STUDY SO BRITISH MEDICAL JOURNAL LA English DT Article C1 SAN FRANCISCO DEPT PUBL HLTH,AIDS OFF,RES BRANCH,CLIN STUDIES SECT,SAN FRANCISCO,CA 94102. SAN FRANCISCO DEPT PUBL HLTH,AIDS OFF,RES BRANCH,DATA MANAGEMENT SECT,SAN FRANCISCO,CA 94102. SAN FRANCISCO DEPT PUBL HLTH,AIDS OFF,RES BRANCH,FIELD STUDIES SECT,SAN FRANCISCO,CA 94102. CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,EPIDEMIOL BRANCH,BEHAV & SOCIAL STUDIES SECT,ATLANTA,GA 30333. CTR DIS CONTROL,CTR INFECT DIS,SPECIAL STUDIES SECT,ATLANTA,GA 30333. FU PHS HHS [U62/CCU900523-03-5] NR 52 TC 248 Z9 253 U1 0 U2 0 PU BRITISH MED JOURNAL PUBL GROUP PI LONDON PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON, ENGLAND WC1H 9JR SN 0959-8138 J9 BRIT MED J JI Br. Med. J. PD NOV 24 PY 1990 VL 301 IS 6762 BP 1183 EP 1188 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA EJ944 UT WOS:A1990EJ94400017 PM 2261554 ER PT J AU KHOSHOO, V BHAN, MK JAYASHREE, S KUMAR, R GLASS, RI AF KHOSHOO, V BHAN, MK JAYASHREE, S KUMAR, R GLASS, RI TI ROTAVIRUS INFECTION AND PERSISTENT DIARRHEA IN YOUNG-CHILDREN SO LANCET LA English DT Letter C1 ALL INDIA INST MED SCI,DEPT PAEDIAT,DIV GASTROENTEROL,NEW DELHI 110016,INDIA. CTR DIS CONTROL,VIRAL GASTROENTERITIS UNIT,ATLANTA,GA 30333. RI Kumar, Rajeev/I-2338-2016 OI Kumar, Rajeev/0000-0002-0783-1101 NR 7 TC 7 Z9 7 U1 0 U2 0 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD NOV 24 PY 1990 VL 336 IS 8726 BP 1314 EP 1315 DI 10.1016/0140-6736(90)92995-T PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA EJ943 UT WOS:A1990EJ94300030 PM 1978133 ER PT J AU MAST, EE BERG, JL HANRAHAN, LP WASSELL, JT DAVIS, JP AF MAST, EE BERG, JL HANRAHAN, LP WASSELL, JT DAVIS, JP TI RISK-FACTORS FOR MEASLES IN A PREVIOUSLY VACCINATED POPULATION AND COST-EFFECTIVENESS OF REVACCINATION STRATEGIES SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 WISCONSIN DEPT HLTH & SOCIAL SERV,BUR COMMUNITY HLTH & PREVENT,POB 309,MADISON,WI 53701. UNIV WISCONSIN,SCH MED,DEPT PEDIAT,MADISON,WI 53706. UNIV WISCONSIN,SCH MED,DEPT PREVENT MED,MADISON,WI 53706. CTR DIS CONTROL,DIV SURVEILLANCE & EPIDEMIOL,EPIDEMIOL PROGRAM OFF,ATLANTA,GA 30333. CTR DIS CONTROL,DIV FIELD SERV,ATLANTA,GA 30333. NR 37 TC 40 Z9 41 U1 0 U2 1 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD NOV 21 PY 1990 VL 264 IS 19 BP 2529 EP 2533 DI 10.1001/jama.264.19.2529 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA EH795 UT WOS:A1990EH79500030 PM 2122013 ER PT J AU CALVERT, GM FAJEN, JM HILLS, BW HALPERIN, WE AF CALVERT, GM FAJEN, JM HILLS, BW HALPERIN, WE TI TESTICULAR CANCER, DIMETHYLFORMAMIDE, AND LEATHER TANNERIES SO LANCET LA English DT Letter RP CALVERT, GM (reprint author), NIOSH,DIV SURVEILLANCE HAZARD EVALUAT & FIELD STUDIES,CINCINNATI,OH 45226, USA. NR 6 TC 20 Z9 21 U1 1 U2 1 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD NOV 17 PY 1990 VL 336 IS 8725 BP 1253 EP 1254 DI 10.1016/0140-6736(90)92870-N PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA EJ064 UT WOS:A1990EJ06400037 PM 1978094 ER PT J AU SOSIN, DM SACKS, JJ HOLMGREEN, P AF SOSIN, DM SACKS, JJ HOLMGREEN, P TI HEAD-INJURY - ASSOCIATED DEATHS FROM MOTORCYCLE CRASHES - RELATIONSHIP TO HELMET-USE LAWS SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV INJURY CONTROL,ATLANTA,GA 30333. NR 28 TC 74 Z9 75 U1 0 U2 8 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD NOV 14 PY 1990 VL 264 IS 18 BP 2395 EP 2399 DI 10.1001/jama.264.18.2395 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA EG589 UT WOS:A1990EG58900027 PM 2231995 ER PT J AU SCHWARTZ, B FACKLAM, RR BREIMAN, RF AF SCHWARTZ, B FACKLAM, RR BREIMAN, RF TI CHANGING EPIDEMIOLOGY OF GROUP-A STREPTOCOCCAL INFECTION IN THE USA SO LANCET LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,RESP DIS BRANCH,LAB SECT,ATLANTA,GA 30333. RP SCHWARTZ, B (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,RESP DIS BRANCH,EPIDEMIOL SECT,MAILSTOP C-09,ATLANTA,GA 30333, USA. NR 28 TC 342 Z9 350 U1 0 U2 2 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD NOV 10 PY 1990 VL 336 IS 8724 BP 1167 EP 1171 DI 10.1016/0140-6736(90)92777-F PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA EG701 UT WOS:A1990EG70100012 PM 1978035 ER PT J AU ALTER, HJ EPSTEIN, JS SWENSON, SG VANRADEN, MJ WARD, JW KASLOW, RA MENITOVE, JE KLEIN, HG SANDLER, SG SAYERS, MH HEWLETT, IK CHERNOFF, AI AF ALTER, HJ EPSTEIN, JS SWENSON, SG VANRADEN, MJ WARD, JW KASLOW, RA MENITOVE, JE KLEIN, HG SANDLER, SG SAYERS, MH HEWLETT, IK CHERNOFF, AI TI PREVALENCE OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 P24 ANTIGEN IN UNITED-STATES BLOOD-DONORS - AN ASSESSMENT OF THE EFFICACY OF TESTING IN DONOR SCREENING SO NEW ENGLAND JOURNAL OF MEDICINE LA English DT Article C1 CTR DIS CONTROL,ATLANTA,GA 30333. PUGET SOUND BLOOD CTR,SEATTLE,WA 98104. MILWAUKEE BLOOD CTR INC,MILWAUKEE,WI 53233. US FDA,WARREN G MAGNUSON CLIN CTR,BETHESDA,MD 20014. BLOOD SYST CENT LAB,SCOTTSDALE,AZ. AMER RED CROSS,WASHINGTON,DC. AMER ASSOC BLOOD BANKS,ARLINGTON,VA. RP ALTER, HJ (reprint author), NIH,BETHESDA,MD 20892, USA. FU PHS HHS [223-89-1000] NR 25 TC 105 Z9 108 U1 0 U2 1 PU MASS MEDICAL SOC PI BOSTON PA 10 SHATTUCK, BOSTON, MA 02115 SN 0028-4793 J9 NEW ENGL J MED JI N. Engl. J. Med. PD NOV 8 PY 1990 VL 323 IS 19 BP 1312 EP 1317 DI 10.1056/NEJM199011083231905 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA EG588 UT WOS:A1990EG58800005 PM 2120589 ER PT J AU LEE, RK SACKS, JJ AF LEE, RK SACKS, JJ TI LATCHKEY CHILDREN AND GUNS AT HOME SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Letter RP LEE, RK (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 3 TC 5 Z9 5 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD NOV 7 PY 1990 VL 264 IS 17 BP 2210 EP 2210 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EF488 UT WOS:A1990EF48800011 PM 2214093 ER PT J AU EDMONSON, MB ADDISS, DG DAVIS, JP AF EDMONSON, MB ADDISS, DG DAVIS, JP TI MEASLES VACCINATION - REPLY SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Letter C1 CTR DIS CONTROL,ATLANTA,GA 30333. WISCONSIN DEPT HLTH & SOCIAL SERV,MADISON,WI. RP EDMONSON, MB (reprint author), UNIV WISCONSIN,MADISON,WI 53706, USA. NR 5 TC 1 Z9 1 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD NOV 7 PY 1990 VL 264 IS 17 BP 2211 EP 2212 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA EF488 UT WOS:A1990EF48800016 ER PT J AU MCELVAINE, MD HARDER, EM JOHNSON, L BAER, RD SATZGER, RD AF MCELVAINE, MD HARDER, EM JOHNSON, L BAER, RD SATZGER, RD TI LEAD-POISONING FROM THE USE OF INDIAN FOLK MEDICINES SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Letter C1 US FDA,BOTHELL,WA. UNIV S FLORIDA,TAMPA,FL 33620. US FDA,CINCINNATI,OH 45267. RP MCELVAINE, MD (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 6 TC 23 Z9 23 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD NOV 7 PY 1990 VL 264 IS 17 BP 2212 EP 2213 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA EF488 UT WOS:A1990EF48800018 PM 2214097 ER PT J AU SACKS, JJ BINDER, S AF SACKS, JJ BINDER, S TI POINTS OF POTENTIAL IQ LOST FROM LEAD SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Letter RP SACKS, JJ (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 2 TC 1 Z9 1 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD NOV 7 PY 1990 VL 264 IS 17 BP 2212 EP 2212 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EF488 UT WOS:A1990EF48800017 PM 2214096 ER PT J AU ALTER, MJ HADLER, SC JUDSON, FN MARES, A ALEXANDER, WJ HU, PY MILLER, JK MOYER, LA FIELDS, HA BRADLEY, DW MARGOLIS, HS AF ALTER, MJ HADLER, SC JUDSON, FN MARES, A ALEXANDER, WJ HU, PY MILLER, JK MOYER, LA FIELDS, HA BRADLEY, DW MARGOLIS, HS TI RISK-FACTORS FOR ACUTE NON-A, NON-B HEPATITIS IN THE UNITED-STATES AND ASSOCIATION WITH HEPATITIS-C VIRUS-INFECTION SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 DENVER DEPT HLTH & HOSP,DENVER,CO. JEFFERSON CTY DEPT HLTH,BIRMINGHAM,AL. TACOMA PIERCE CTY DEPT HLTH,TACOMA,WA. PINELLAS CTY DEPT HLTH,ST PETERSBURG,FL. RP ALTER, MJ (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,HEPATITIS BRANCH,BLDG 6,ROOM 154 A-33,ATLANTA,GA 30333, USA. FU FDA HHS [FDA 224-85-1001] NR 26 TC 563 Z9 567 U1 1 U2 12 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD NOV 7 PY 1990 VL 264 IS 17 BP 2231 EP 2235 DI 10.1001/jama.264.17.2231 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA EF488 UT WOS:A1990EF48800027 PM 2170702 ER PT J AU ENG, TR HARKESS, JR FISHBEIN, DB DAWSON, JE GREENE, CN REDUS, MA SATALOWICH, FT AF ENG, TR HARKESS, JR FISHBEIN, DB DAWSON, JE GREENE, CN REDUS, MA SATALOWICH, FT TI EPIDEMIOLOGIC, CLINICAL, AND LABORATORY FINDINGS OF HUMAN EHRLICHIOSIS IN THE UNITED-STATES, 1988 SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 OKLAHOMA DEPT HLTH,OKLAHOMA CITY,OK. CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,ATLANTA,GA 30333. MISSOURI STATE DEPT HLTH,JEFFERSON CITY,MO. NR 53 TC 119 Z9 123 U1 0 U2 4 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD NOV 7 PY 1990 VL 264 IS 17 BP 2251 EP 2258 DI 10.1001/jama.264.17.2251 PG 8 WC Medicine, General & Internal SC General & Internal Medicine GA EF488 UT WOS:A1990EF48800031 PM 2214103 ER PT J AU FOUNG, S PERKINS, S KAFADAR, K GESSNER, P ZIMMERMANN, U AF FOUNG, S PERKINS, S KAFADAR, K GESSNER, P ZIMMERMANN, U TI DEVELOPMENT OF MICROFUSION TECHNIQUES TO GENERATE HUMAN HYBRIDOMAS SO JOURNAL OF IMMUNOLOGICAL METHODS LA English DT Article C1 UNIV WURZBURG,INST BIOTECHNOL,W-8700 WURZBURG,GERMANY. STANFORD UNIV,MED CTR,SCH MED,DEPT PATHOL,STANFORD,CA 94305. CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,STAT & SURVEILLANCE BRANCH,ATLANTA,GA 30333. FU NHLBI NIH HHS [HL33811]; NIAID NIH HHS [AI22557, AI26031] NR 16 TC 21 Z9 21 U1 0 U2 1 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0022-1759 J9 J IMMUNOL METHODS JI J. Immunol. Methods PD NOV 6 PY 1990 VL 134 IS 1 BP 35 EP 42 DI 10.1016/0022-1759(90)90109-9 PG 8 WC Biochemical Research Methods; Immunology SC Biochemistry & Molecular Biology; Immunology GA EG522 UT WOS:A1990EG52200003 PM 2172386 ER PT J AU DOLL, LS JUDSON, FN OSTROW, DG OMALLEY, PM DARROW, WW HADLER, SC BYERS, RH PENLEY, KA ALTMAN, NL AF DOLL, LS JUDSON, FN OSTROW, DG OMALLEY, PM DARROW, WW HADLER, SC BYERS, RH PENLEY, KA ALTMAN, NL TI SEXUAL-BEHAVIOR BEFORE AIDS - THE HEPATITIS-B STUDIES OF HOMOSEXUAL AND BISEXUAL MEN SO AIDS LA English DT Article C1 DENVER DIS CONTROL SERV,DENVER,CO. UNIV MICHIGAN,MIDWEST AIDS BIOBEHAV RES CTR,ANN ARBOR,MI 48109. SAN FRANCISCO DEPT PUBL HLTH,AIDS OFF,SAN FRANCISCO,CA. HOWARD BROWN MEM CLIN,CHICAGO,IL. RP DOLL, LS (reprint author), CTR DIS CONTROL,DIV HIV AIDS,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 22 TC 15 Z9 15 U1 0 U2 0 PU RAPID SCIENCE PUBLISHERS PI LONDON PA 2-6 BOUNDARY ROW, LONDON, ENGLAND SE1 8NH SN 0269-9370 J9 AIDS JI Aids PD NOV PY 1990 VL 4 IS 11 BP 1067 EP 1073 DI 10.1097/00002030-199011000-00003 PG 7 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA EN374 UT WOS:A1990EN37400003 PM 2282178 ER PT J AU LAIRMORE, MD LERCHE, NW SCHULTZ, KT STONE, CM BROWN, BG HERMANN, LM YEE, JA JENNINGS, M AF LAIRMORE, MD LERCHE, NW SCHULTZ, KT STONE, CM BROWN, BG HERMANN, LM YEE, JA JENNINGS, M TI SIV, STLV-I, AND TYPE-D RETROVIRUS ANTIBODIES IN CAPTIVE RHESUS MACAQUES AND IMMUNOBLOT REACTIVITY TO SIV P27 IN HUMAN AND RHESUS-MONKEY SERA SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,RETROVIRUS DIS BRANCH,ATLANTA,GA 30333. UNIV CALIF DAVIS,CALIF PRIMATE RES CTR,DAVIS,CA 95616. UNIV WISCONSIN,WISCONSIN REG PRIMATE RES CTR,DEPT PATHOBIOL SCI,MADISON,WI 53706. CTR DIS CONTROL,CTR INFECT DIS,ANIM RESOURCES BRANCH,ATLANTA,GA 30333. NR 19 TC 26 Z9 26 U1 0 U2 0 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PD NOV PY 1990 VL 6 IS 11 BP 1233 EP 1238 PG 6 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA EK810 UT WOS:A1990EK81000002 PM 1706606 ER PT J AU OU, CY MCDONOUGH, SH CABANAS, D RYDER, TB HARPER, M MOORE, J SCHOCHETMAN, G AF OU, CY MCDONOUGH, SH CABANAS, D RYDER, TB HARPER, M MOORE, J SCHOCHETMAN, G TI RAPID AND QUANTITATIVE DETECTION OF ENZYMATICALLY AMPLIFIED HIV-1 DNA USING CHEMILUMINESCENT OLIGONUCLEOTIDE PROBES SO AIDS RESEARCH AND HUMAN RETROVIRUSES LA English DT Article C1 GENPROBE INC,SAN DIEGO,CA. RP OU, CY (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,MAILSTOP D-12,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 25 TC 64 Z9 65 U1 0 U2 0 PU MARY ANN LIEBERT INC PUBL PI LARCHMONT PA 2 MADISON AVENUE, LARCHMONT, NY 10538 SN 0889-2229 J9 AIDS RES HUM RETROV JI Aids Res. Hum. Retrovir. PD NOV PY 1990 VL 6 IS 11 BP 1323 EP 1329 PG 7 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA EK810 UT WOS:A1990EK81000014 PM 2078413 ER PT J AU BARON, PA PLATEK, SF AF BARON, PA PLATEK, SF TI NIOSH METHOD 7402-ASBESTOS FIBERS (REVISION =1) - LOW-TEMPERATURE ASHING OF FILTER SAMPLES SO AMERICAN INDUSTRIAL HYGIENE ASSOCIATION JOURNAL LA English DT Article RP BARON, PA (reprint author), NIOSH,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 8 TC 0 Z9 0 U1 0 U2 0 PU AMER INDUSTRIAL HYGIENE ASSOC PI FAIRFAX PA 2700 PROSPERITY AVE #250, FAIRFAX, VA 22031-4307 SN 0002-8894 J9 AM IND HYG ASSOC J JI Am. Ind. Hyg. Assoc. J. PD NOV PY 1990 VL 51 IS 11 BP A730 EP A731 PG 2 WC Environmental Sciences; Public, Environmental & Occupational Health SC Environmental Sciences & Ecology; Public, Environmental & Occupational Health GA EJ758 UT WOS:A1990EJ75800010 PM 2085160 ER PT J AU POTISCHMAN, N MCCULLOCH, CE BYERS, T NEMOTO, T STUBBE, N MILCH, R PARKER, R RASMUSSEN, KM ROOT, M GRAHAM, S CAMPBELL, TC AF POTISCHMAN, N MCCULLOCH, CE BYERS, T NEMOTO, T STUBBE, N MILCH, R PARKER, R RASMUSSEN, KM ROOT, M GRAHAM, S CAMPBELL, TC TI BREAST-CANCER AND DIETARY AND PLASMA-CONCENTRATIONS OF CAROTENOIDS AND VITAMIN-A SO AMERICAN JOURNAL OF CLINICAL NUTRITION LA English DT Article C1 CORNELL UNIV,DIV NUTR SCI,ITHACA,NY 14853. CORNELL UNIV,BIOMETR UNIT,ITHACA,NY 14853. CTR DIS CONTROL,DIV NUTR,EPIDEMIOL BRANCH,ATLANTA,GA 30333. SUNY BUFFALO,BUFFALO GEN HOSP,ROSWELL PK MEM INST,BUFFALO,NY 14260. SUNY BUFFALO,DEPT SOCIAL & PREVENT MED,BUFFALO,NY 14260. FU NCI NIH HHS [CA11535, CA34205] NR 61 TC 91 Z9 92 U1 0 U2 2 PU AMER SOC CLIN NUTRITION INC PI BETHESDA PA 9650 ROCKVILLE PIKE SUBSCRIPTIONS, RM L-2310, BETHESDA, MD 20814-3998 SN 0002-9165 J9 AM J CLIN NUTR JI Am. J. Clin. Nutr. PD NOV PY 1990 VL 52 IS 5 BP 909 EP 915 PG 7 WC Nutrition & Dietetics SC Nutrition & Dietetics GA EF095 UT WOS:A1990EF09500023 PM 2239767 ER PT J AU ADAMI, HO ZACK, M KRESSNER, U PERSSON, I BERGLUND, A NAESSEN, T BERGKVIST, L AF ADAMI, HO ZACK, M KRESSNER, U PERSSON, I BERGLUND, A NAESSEN, T BERGKVIST, L TI HIP-FRACTURES IN WOMEN WITH BREAST-CANCER SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Article C1 UNIV HOSP UPPSALA,DEPT GYNECOL & OBSTET,S-75185 UPPSALA,SWEDEN. UNIV UPPSALA,CTR DATA,S-75105 UPPSALA,SWEDEN. CTR DIS CONTROL,ATLANTA,GA 30333. RP ADAMI, HO (reprint author), UNIV HOSP UPPSALA,DEPT SURG,CANC EPIDEMIOL UNIT,S-75185 UPPSALA,SWEDEN. NR 31 TC 25 Z9 25 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD NOV PY 1990 VL 132 IS 5 BP 877 EP 883 PG 7 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EG027 UT WOS:A1990EG02700006 PM 2239902 ER PT J AU ADDISS, DG SHAFFER, N FOWLER, BS TAUXE, RV AF ADDISS, DG SHAFFER, N FOWLER, BS TAUXE, RV TI THE EPIDEMIOLOGY OF APPENDICITIS AND APPENDECTOMY IN THE UNITED-STATES SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Article RP ADDISS, DG (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,ENTER DIS BRANCH,MAILSTOP C-09,ATLANTA,GA 30333, USA. NR 77 TC 739 Z9 766 U1 2 U2 15 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD NOV PY 1990 VL 132 IS 5 BP 910 EP 925 PG 16 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EG027 UT WOS:A1990EG02700010 PM 2239906 ER PT J AU CHU, SY BUEHLER, JW FLEMING, PL BERKELMAN, RL AF CHU, SY BUEHLER, JW FLEMING, PL BERKELMAN, RL TI EPIDEMIOLOGY OF REPORTED CASES OF AIDS IN LESBIANS, UNITED-STATES 1980-89 SO AMERICAN JOURNAL OF PUBLIC HEALTH LA English DT Note RP CHU, SY (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,GZ9,ATLANTA,GA 30333, USA. RI Buehler, James/B-8419-2014 NR 6 TC 39 Z9 39 U1 0 U2 0 PU AMER PUBLIC HEALTH ASSN INC PI WASHINGTON PA 1015 FIFTEENTH ST NW, WASHINGTON, DC 20005 SN 0090-0036 J9 AM J PUBLIC HEALTH JI Am. J. Public Health PD NOV PY 1990 VL 80 IS 11 BP 1380 EP 1381 DI 10.2105/AJPH.80.11.1380 PG 2 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EF801 UT WOS:A1990EF80100022 PM 2240312 ER PT J AU HEIMBERGER, T JENKINS, S RUSSELL, H DUMA, R AF HEIMBERGER, T JENKINS, S RUSSELL, H DUMA, R TI EPIDEMIOLOGY OF LYME-DISEASE IN VIRGINIA SO AMERICAN JOURNAL OF THE MEDICAL SCIENCES LA English DT Article C1 VIRGINIA COMMONWEALTH UNIV,MED COLL VIRGINIA,DIV INFECT DIS,BOX 49,MCV STN,RICHMOND,VA 23298. CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,RESP DIS BRANCH,ATLANTA,GA 30333. VIRGINIA DEPT HLTH,DIV EPIDEMIOL,RICHMOND,VA. NR 16 TC 4 Z9 4 U1 0 U2 2 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0002-9629 J9 AM J MED SCI JI Am. J. Med. Sci. PD NOV PY 1990 VL 300 IS 5 BP 283 EP 287 DI 10.1097/00000441-199011000-00002 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA EL375 UT WOS:A1990EL37500002 PM 2240015 ER PT J AU COCHRANE, AH NARDIN, EH DEARRUDA, M MARACIC, M CLAVIJO, P COLLINS, WE NUSSENZWEIG, RS AF COCHRANE, AH NARDIN, EH DEARRUDA, M MARACIC, M CLAVIJO, P COLLINS, WE NUSSENZWEIG, RS TI WIDESPREAD REACTIVITY OF HUMAN SERA WITH A VARIANT REPEAT OF THE CIRCUMSPOROZOITE PROTEIN OF PLASMODIUM-VIVAX SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,ATLANTA,GA 30333. INST OSWALDO CRUZ,RIO DE JANEIRO,BRAZIL. RP COCHRANE, AH (reprint author), NYU,SCH MED,DEPT MED & MOLEC PARASITOL,341 E 25TH ST,NEW YORK,NY 10010, USA. NR 16 TC 42 Z9 43 U1 0 U2 0 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD NOV PY 1990 VL 43 IS 5 BP 446 EP 451 PG 6 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA EL126 UT WOS:A1990EL12600003 PM 2122747 ER PT J AU JONES, WD AF JONES, WD TI GEOGRAPHIC-DISTRIBUTION OF PHAGE TYPES AMONG CULTURES OF MYCOBACTERIUM-TUBERCULOSIS .2. CULTURES FROM INDIA AND SOUTH-AFRICA SO AMERICAN REVIEW OF RESPIRATORY DISEASE LA English DT Article RP JONES, WD (reprint author), CTR DIS CONTROL,DIV BACTERIAL DIS,RESP DIS BRANCH,MYCOBACTERIOL LAB,ATLANTA,GA 30333, USA. NR 10 TC 7 Z9 7 U1 0 U2 1 PU AMER LUNG ASSOC PI NEW YORK PA 1740 BROADWAY, NEW YORK, NY 10019 SN 0003-0805 J9 AM REV RESPIR DIS JI Am. Rev. Respir. Dis. PD NOV PY 1990 VL 142 IS 5 BP 1000 EP 1003 PG 4 WC Respiratory System SC Respiratory System GA EG088 UT WOS:A1990EG08800003 PM 2122783 ER PT J AU HOLMBERG, SD AF HOLMBERG, SD TI THE RISE OF TUBERCULOSIS IN AMERICA BEFORE 1820 SO AMERICAN REVIEW OF RESPIRATORY DISEASE LA English DT Editorial Material RP HOLMBERG, SD (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,MAILSTOP G29,ATLANTA,GA 30333, USA. NR 66 TC 6 Z9 6 U1 0 U2 1 PU AMER LUNG ASSOC PI NEW YORK PA 1740 BROADWAY, NEW YORK, NY 10019 SN 0003-0805 J9 AM REV RESPIR DIS JI Am. Rev. Respir. Dis. PD NOV PY 1990 VL 142 IS 5 BP 1228 EP 1232 PG 5 WC Respiratory System SC Respiratory System GA EG088 UT WOS:A1990EG08800047 PM 2240850 ER PT J AU ANDERSON, RL VESS, RW PANLILIO, AL FAVERO, MS AF ANDERSON, RL VESS, RW PANLILIO, AL FAVERO, MS TI PROLONGED SURVIVAL OF PSEUDOMONAS-CEPACIA IN COMMERCIALLY MANUFACTURED POVIDONE-IODINE SO APPLIED AND ENVIRONMENTAL MICROBIOLOGY LA English DT Note RP ANDERSON, RL (reprint author), CTR DIS CONTROL,CTR INFECT DIS,HOSP INFECT PROGRAM,NOSOCOMIAL INFECT LAB BRANCH,ATLANTA,GA 30333, USA. NR 15 TC 26 Z9 30 U1 0 U2 1 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0099-2240 J9 APPL ENVIRON MICROB JI Appl. Environ. Microbiol. PD NOV PY 1990 VL 56 IS 11 BP 3598 EP 3600 PG 3 WC Biotechnology & Applied Microbiology; Microbiology SC Biotechnology & Applied Microbiology; Microbiology GA EF663 UT WOS:A1990EF66300061 PM 2268166 ER PT J AU MATTE, TD HOFFMAN, RE ROSENMAN, KD STANBURY, M AF MATTE, TD HOFFMAN, RE ROSENMAN, KD STANBURY, M TI SURVEILLANCE OF OCCUPATIONAL ASTHMA UNDER THE SENSOR MODEL SO CHEST LA English DT Article C1 NEW JERSEY STATE DEPT HLTH,TRENTON,NJ. COLORADO DEPT HLTH,DENVER,CO. MICHIGAN STATE UNIV,COLL HUMAN MED,E LANSING,MI 48824. RP MATTE, TD (reprint author), CTR DIS CONTROL,NIOSH,ATLANTA,GA 30333, USA. NR 17 TC 44 Z9 45 U1 0 U2 0 PU AMER COLL CHEST PHYSICIANS PI NORTHBROOK PA 3300 DUNDEE ROAD, NORTHBROOK, IL 60062-2348 SN 0012-3692 J9 CHEST JI Chest PD NOV PY 1990 VL 98 IS 5 SU S BP S173 EP S178 DI 10.1378/chest.98.5_Supplement.173S PG 6 WC Critical Care Medicine; Respiratory System SC General & Internal Medicine; Respiratory System GA EH100 UT WOS:A1990EH10000006 PM 2226005 ER PT J AU TEN, RM KEPHART, GM POSADA, M ABAITUA, I SOLDEVILLA, L KILBOURNE, EM DUNNETTE, SL GLEICH, GJ AF TEN, RM KEPHART, GM POSADA, M ABAITUA, I SOLDEVILLA, L KILBOURNE, EM DUNNETTE, SL GLEICH, GJ TI PARTICIPATION OF EOSINOPHILS IN THE TOXIC OIL SYNDROME SO CLINICAL AND EXPERIMENTAL IMMUNOLOGY LA English DT Article C1 MAYO CLIN & MAYO FDN,DEPT IMMUNOL,ROCHESTER,MN 55905. FONDO INVEST SANITARIAS SEGURIDAD SOCIAL,MADRID,SPAIN. CTR DIS CONTROL,ATLANTA,GA 30333. MAYO CLIN & MAYO GRAD SCH MED,DEPT IMMUNOL,ROCHESTER,MN 55901. MAYO CLIN & MAYO GRAD SCH MED,DEPT MED,ROCHESTER,MN 55901. OI Posada, Manuel/0000-0002-8372-4180 FU NIAID NIH HHS [AI 15231] NR 28 TC 26 Z9 26 U1 0 U2 1 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0009-9104 J9 CLIN EXP IMMUNOL JI Clin. Exp. Immunol. PD NOV PY 1990 VL 82 IS 2 BP 313 EP 317 PG 5 WC Immunology SC Immunology GA EE858 UT WOS:A1990EE85800021 PM 2242612 ER PT J AU HENDERSON, LO POWELL, MK SMITH, SJ HANNON, WH COOPER, GR MARCOVINA, SM AF HENDERSON, LO POWELL, MK SMITH, SJ HANNON, WH COOPER, GR MARCOVINA, SM TI IMPACT OF PROTEIN MEASUREMENTS ON STANDARDIZATION OF ASSAYS OF APOLIPOPROTEIN-A-I AND APOLIPOPROTEIN-B SO CLINICAL CHEMISTRY LA English DT Article C1 HOSP SAN RAFFAELE,MILAN,ITALY. SCI INST SAN RAFFAELE,IMMUNOCHEM LAB,MILAN,ITALY. SCI INST SAN RAFFAELE,LIPOPROT LAB,MILAN,ITALY. RP HENDERSON, LO (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,1600 CLIFTON RD,F-19,ATLANTA,GA 30333, USA. NR 26 TC 19 Z9 19 U1 0 U2 1 PU AMER ASSOC CLINICAL CHEMISTRY PI WASHINGTON PA 2101 L STREET NW, SUITE 202, WASHINGTON, DC 20037-1526 SN 0009-9147 J9 CLIN CHEM JI Clin. Chem. PD NOV PY 1990 VL 36 IS 11 BP 1911 EP 1917 PG 7 WC Medical Laboratory Technology SC Medical Laboratory Technology GA EJ838 UT WOS:A1990EJ83800012 PM 2242569 ER PT J AU CLARK, NC HILL, BC OHARA, CM STEINGRIMSSON, O COOKSEY, RC AF CLARK, NC HILL, BC OHARA, CM STEINGRIMSSON, O COOKSEY, RC TI EPIDEMIOLOGIC TYPING OF ENTEROBACTER-SAKAZAKII IN 2 NEONATAL NOSOCOMIAL OUTBREAKS SO DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE LA English DT Article ID MULTILOCUS ENZYME ELECTROPHORESIS; MENINGITIS; CLOACAE; MILK AB Two unrelated hospital outbreaks of Enterobacter sakazakii, involving meningitis, bacteremia, and colonization of neonates, were investigated. In each of these outbreaks, E. sakazakii was isolated from both patients and dried infant formula. In previous outbreaks, the source and mode of transmission of E. sakazakii in neonatal infections was not determined. In this study, we used a combination of typing methods (plasmid analysis, antibiograms, chromosomal restriction endonuclease analysis, ribotyping, and multilocus enzyme electrophoresis) to evaluate the isolates from each outbreak as to the relatedness. The typing results differed among outbreaks, but in each one, patient and formula isolates shared the same typing pattern. The only exceptions were disk antibiograms, which often varied among colonies selected from each of the isolates. Plasmid analysis, chromosomal restriction endonuclease analysis, ribotyping, and multilocus enzyme electrophoresis all were effective as epidemiological typing methods for E. sakazakii, especially when used in combination. By using this typing scheme, we have confirmed that E. sakazakii from intrinsically contaminated dried infant formula was the source of neonatal infection. C1 CTR DIS CONTROL,NOSOCOMIAL INFECT LAB BRANCH,ATLANTA,GA 30333. CTR DIS CONTROL,CTR INFECT DIS,HOSP INFECT PROGRAM,ATLANTA,GA 30333. UNIV HOSP ICELAND,REYKJAVIK,ICELAND. RP CLARK, NC (reprint author), CTR DIS CONTROL,ANTIMICROB INVEST BRANCH,BLDG 5,ROOM 235 G07,ATLANTA,GA 30333, USA. NR 22 TC 118 Z9 123 U1 2 U2 3 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0732-8893 J9 DIAGN MICR INFEC DIS JI Diagn. Microbiol. Infect. Dis. PD NOV-DEC PY 1990 VL 13 IS 6 BP 467 EP 472 DI 10.1016/0732-8893(90)90078-A PG 6 WC Infectious Diseases; Microbiology SC Infectious Diseases; Microbiology GA EN930 UT WOS:A1990EN93000004 PM 2279379 ER PT J AU JONES, RN FUCHS, PC WASHINGTON, JA GAVAN, TL MURRAY, PR GERLACH, EH THORNSBERRY, C AF JONES, RN FUCHS, PC WASHINGTON, JA GAVAN, TL MURRAY, PR GERLACH, EH THORNSBERRY, C TI INTERPRETIVE CRITERIA, QUALITY-CONTROL GUIDELINES, AND DRUG STABILITY STUDIES FOR SUSCEPTIBILITY TESTING OF CEFOTAXIME, CEFOXITIN, CEFTAZIDIME, AND CEFUROXIME AGAINST NEISSERIA-GONORRHOEAE SO DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE LA English DT Article ID UNCOMPLICATED GONORRHEA; GONOCOCCAL INFECTIONS; RESISTANT; AXETIL; PENICILLIN; STRAINS; SPECTINOMYCIN; MEZLOCILLIN; URETHRITIS AB Cefotaxime, cefoxitin, ceftazidime, and cefuroxime were tested in a multicenter study to establish susceptibility testing criteria and quality control guidelines for Neisseria gonorrhoeae. Interpretive criteria were established by using triplicate testing of at least 100 gonococcal strains having various susceptibility patterns to currently utilized drug regimens. Only a susceptible category was proposed for cefotaxime and ceftazidime (greater-than-or-equal-to-31 mm and less-than-or-equal-to-0.5-mu-g/ml) because of rare resistant isolates. The other interpretive criteria were cefoxitin-susceptible, greater-than-or-equal-to-28 mm (less-than-or-equal-to-2-mu-g/ml); intermediate, 24-27 mm (4-mu-g/ml), and resistant, less-than-or-equal-to-23 mm (greater-than-or-equal-to-8-mu-g/ml); cefuroxime-susceptible, greater-than-or-equal-to-31 mm (less-than-or-equal-to-1-mu-g/ml); moderately susceptible, 26-30 mm (2-mu-g/ml); and resistant, less-than-or-equal-to-25 mm (greater-than-or-equal-to-4-mu-g/ml). Quality control criteria were established by using multiple agar lots, three disk lots, and a number of replicates consistent with National Committee for Clinical Laboratory Standards M23-T guidelines. C1 ST VINCENT HOSP & MED CTR,PORTLAND,OR. CLIN MICROBIOL INST INC,TUALATIN,OR. CLEVELAND CLIN EDUC FDN,CLEVELAND,OH 44106. WASHINGTON UNIV,ST LOUIS,MO 63130. ST FRANCIS REG MED CTR,WICHITA,KS 67214. CTR DIS CONTROL,ATLANTA,GA 30333. NR 39 TC 14 Z9 14 U1 0 U2 2 PU ELSEVIER SCIENCE INC PI NEW YORK PA 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 SN 0732-8893 J9 DIAGN MICR INFEC DIS JI Diagn. Microbiol. Infect. Dis. PD NOV-DEC PY 1990 VL 13 IS 6 BP 499 EP 507 DI 10.1016/0732-8893(90)90082-7 PG 9 WC Infectious Diseases; Microbiology SC Infectious Diseases; Microbiology GA EN930 UT WOS:A1990EN93000008 PM 2126232 ER PT J AU ANDERSON, JE KANN, L HOLTZMAN, D ARDAY, S TRUMAN, B KOLBE, L AF ANDERSON, JE KANN, L HOLTZMAN, D ARDAY, S TRUMAN, B KOLBE, L TI HIV/AIDS KNOWLEDGE AND SEXUAL-BEHAVIOR AMONG HIGH-SCHOOL-STUDENTS SO FAMILY PLANNING PERSPECTIVES LA English DT Article ID ACQUIRED IMMUNODEFICIENCY SYNDROME; HOMOSEXUAL MEN; ADOLESCENTS; ATTITUDES; BELIEFS; AIDS C1 CTR DIS CONTROL,SCH HLTH,CTR CHRON DIS PREVENT & HLTH PROMOT,ATLANTA,GA 30333. RP ANDERSON, JE (reprint author), CTR DIS CONTROL,DIV ADOLESCENT,ATLANTA,GA 30333, USA. NR 18 TC 109 Z9 109 U1 0 U2 4 PU ALAN GUTTMACHER INST PI NEW YORK PA 120 WALL STREET, NEW YORK, NY 10005 SN 0014-7354 J9 FAM PLANN PERSPECT JI Fam. Plann. Perspect. PD NOV-DEC PY 1990 VL 22 IS 6 BP 252 EP 255 DI 10.2307/2135681 PG 4 WC Demography; Family Studies SC Demography; Family Studies GA ER497 UT WOS:A1990ER49700002 PM 2289542 ER PT J AU WILLIAMS, J GLADEN, BC SCHRADER, SM TURNER, TW PHELPS, JL CHAPIN, RE AF WILLIAMS, J GLADEN, BC SCHRADER, SM TURNER, TW PHELPS, JL CHAPIN, RE TI SEMEN ANALYSIS AND FERTILITY ASSESSMENT IN RABBITS - STATISTICAL POWER AND DESIGN CONSIDERATIONS FOR TOXICOLOGY STUDIES SO FUNDAMENTAL AND APPLIED TOXICOLOGY LA English DT Article C1 NIEHS,NATL TOXICOL PROGRAM,DEV & REPROD TOXICOL GRP,RES TRIANGLE PK,NC 27709. NIEHS,NATL TOXICOL PROGRAM,STAT & BIOMATH BRANCH,RES TRIANGLE PK,NC 27709. NIOSH,EXPTL TOXICOL BRANCH,CINCINNATI,OH 45226. RI Schrader, Steven/E-8120-2011; OI Chapin, Robert/0000-0002-5997-1261 NR 34 TC 34 Z9 34 U1 0 U2 0 PU ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS PI SAN DIEGO PA 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 SN 0272-0590 J9 FUND APPL TOXICOL JI Fundam. Appl. Toxicol. PD NOV PY 1990 VL 15 IS 4 BP 651 EP 665 DI 10.1016/0272-0590(90)90182-J PG 15 WC Toxicology SC Toxicology GA EL666 UT WOS:A1990EL66600003 PM 2086311 ER PT J AU ZAKI, SR AUSTIN, GE CHAN, WC CONATY, AL TRUSLER, S TRAPPIER, S LINDSEY, RB SWAN, DC AF ZAKI, SR AUSTIN, GE CHAN, WC CONATY, AL TRUSLER, S TRAPPIER, S LINDSEY, RB SWAN, DC TI CHROMOSOMAL LOCALIZATION OF THE HUMAN MYELOPEROXIDASE GENE BY INSITU HYBRIDIZATION USING OLIGONUCLEOTIDE PROBES SO GENES CHROMOSOMES & CANCER LA English DT Article C1 CTR DIS CONTROL,DIV IMMUNOL ONCOL & HEMATOL DIS,ATLANTA,GA 30333. EMORY UNIV,SCH MED,DEPT PATHOL,ATLANTA,GA 30322. VET ADM MED CTR,ATLANTA,GA. NR 22 TC 13 Z9 13 U1 0 U2 2 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 1045-2257 J9 GENE CHROMOSOME CANC JI Gene Chromosomes Cancer PD NOV PY 1990 VL 2 IS 4 BP 266 EP 270 DI 10.1002/gcc.2870020403 PG 5 WC Oncology; Genetics & Heredity SC Oncology; Genetics & Heredity GA EL883 UT WOS:A1990EL88300002 PM 2176540 ER PT J AU CROFFORD, LJ RADER, JI DALAKAS, MC HILL, RH PAGE, SW NEEDHAM, LL BRADY, LS HEYES, MP WILDER, RL GOLD, PW ILLA, I SMITH, C STERNBERG, EM AF CROFFORD, LJ RADER, JI DALAKAS, MC HILL, RH PAGE, SW NEEDHAM, LL BRADY, LS HEYES, MP WILDER, RL GOLD, PW ILLA, I SMITH, C STERNBERG, EM TI L-TRYPTOPHAN IMPLICATED IN HUMAN EOSINOPHILIA-MYALGIA-SYNDROME CAUSES FASCIITIS AND PERIMYOSITIS IN THE LEWIS RAT SO JOURNAL OF CLINICAL INVESTIGATION LA English DT Note C1 NIMH, BLDG 10, ROOM 35231, 9000 ROCKVILLE PIKE, BETHESDA, MD 20892 USA. NIAMSD, BETHESDA, MD 20892 USA. NINCDS, BETHESDA, MD 20892 USA. US FDA, CTR FOOD SAFETY & APPL NUTR, WASHINGTON, DC 20204 USA. CTR DIS CONTROL, ATLANTA, GA 30333 USA. RI Needham, Larry/E-4930-2011; Crofford, Leslie/J-8010-2013 NR 39 TC 113 Z9 113 U1 0 U2 1 PU AMER SOC CLINICAL INVESTIGATION INC PI ANN ARBOR PA 35 RESEARCH DR, STE 300, ANN ARBOR, MI 48103 USA SN 0021-9738 EI 1558-8238 J9 J CLIN INVEST JI J. Clin. Invest. PD NOV PY 1990 VL 86 IS 5 BP 1757 EP 1763 DI 10.1172/JCI114902 PG 7 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA EJ186 UT WOS:A1990EJ18600052 PM 2243145 ER PT J AU HEBERT, GA AF HEBERT, GA TI HEMOLYSINS AND OTHER CHARACTERISTICS THAT HELP DIFFERENTIATE AND BIOTYPE STAPHYLOCOCCUS-LUGDUNENSIS AND STAPHYLOCOCCUS-SCHLEIFERI SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article RP HEBERT, GA (reprint author), CTR DIS CONTROL,CTR INFECT DIS,ANTIMICROB INVEST BRANCH,HOSP INFECT PROGRAM,ATLANTA,GA 30333, USA. NR 12 TC 50 Z9 51 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD NOV PY 1990 VL 28 IS 11 BP 2425 EP 2431 PG 7 WC Microbiology SC Microbiology GA EE245 UT WOS:A1990EE24500009 PM 2254418 ER PT J AU WATHENGRADY, HG BRITT, LE STROCKBINE, NA WACHSMUTH, IK AF WATHENGRADY, HG BRITT, LE STROCKBINE, NA WACHSMUTH, IK TI CHARACTERIZATION OF SHIGELLA-DYSENTERIAE SEROTYPE-11, SEROTYPE-12, AND SEROTYPE-13 SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Note C1 CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,WHO,ATLANTA,GA 30333. NR 19 TC 11 Z9 11 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD NOV PY 1990 VL 28 IS 11 BP 2580 EP 2584 PG 5 WC Microbiology SC Microbiology GA EE245 UT WOS:A1990EE24500041 PM 1701447 ER PT J AU POYRY, T KINNUNEN, L KAPSENBERG, J KEW, O HOVI, T AF POYRY, T KINNUNEN, L KAPSENBERG, J KEW, O HOVI, T TI TYPE-3-POLIOVIRUS FINLAND 1984 IS GENETICALLY RELATED TO COMMON MEDITERRANEAN STRAINS SO JOURNAL OF GENERAL VIROLOGY LA English DT Article C1 NATL PUBL HLTH INST,DEPT VIROL,ENTEROVIRUS LAB,MANNERHEIMINTIE 16,SF-00300 HELSINKI,FINLAND. NATL PUBL HLTH INST,MOLEC BIOL UNIT,SF-00300 HELSINKI,FINLAND. RIJKSINST VOLKSGEZONDHEID MILIEUHYG,BILTHOVEN,NETHERLANDS. CTR DIS CONTROL,DIV VIRAL DIS,ATLANTA,GA 30333. RI Kinnunen, Leena/B-7059-2012 OI Kinnunen, Leena/0000-0001-8739-4812 NR 24 TC 29 Z9 29 U1 0 U2 0 PU SOC GENERAL MICROBIOLOGY PI READING PA HARVEST HOUSE 62 LONDON ROAD, READING, BERKS, ENGLAND RG1 5AS SN 0022-1317 J9 J GEN VIROL JI J. Gen. Virol. PD NOV PY 1990 VL 71 BP 2535 EP 2541 DI 10.1099/0022-1317-71-11-2535 PN 11 PG 7 WC Biotechnology & Applied Microbiology; Virology SC Biotechnology & Applied Microbiology; Virology GA EH731 UT WOS:A1990EH73100006 PM 1701473 ER PT J AU REDD, SC RUTHERFORD, GW SANDE, MA LIFSON, AR HADLEY, WK FACKLAM, RR SPIKA, JS AF REDD, SC RUTHERFORD, GW SANDE, MA LIFSON, AR HADLEY, WK FACKLAM, RR SPIKA, JS TI THE ROLE OF HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION IN PNEUMOCOCCAL BACTEREMIA IN SAN-FRANCISCO RESIDENTS SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article C1 UNIV CALIF SAN FRANCISCO,SAN FRANCISCO,CA 94143. SAN FRANCISCO GEN HOSP,SAN FRANCISCO,CA 94110. SAN FRANCISCO DEPT PUBL HLTH,SAN FRANCISCO,CA. RP REDD, SC (reprint author), CTR DIS CONTROL,DIV BACTERIAL DIS,RESP DIS BRANCH,ATLANTA,GA 30333, USA. NR 41 TC 234 Z9 236 U1 1 U2 1 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD NOV PY 1990 VL 162 IS 5 BP 1012 EP 1017 PG 6 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EE046 UT WOS:A1990EE04600002 PM 2230229 ER PT J AU CHEN, RT MARKOWITZ, LE ALBRECHT, P STEWART, JA MOFENSON, LM PREBLUD, SR ORENSTEIN, WA AF CHEN, RT MARKOWITZ, LE ALBRECHT, P STEWART, JA MOFENSON, LM PREBLUD, SR ORENSTEIN, WA TI MEASLES ANTIBODY - REEVALUATION OF PROTECTIVE TITERS SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL DIS,ATLANTA,GA 30333. US FDA,CTR BIOL EVALUAT & RES,BETHESDA,MD 20014. MASSACHUSETTS DEPT PUBL HLTH,DIV COMMUNICABLE DIS CONTROL,BOSTON,MA. RP CHEN, RT (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,DIV IMMUNIZAT,TECH INFORMAT SERV E06,ATLANTA,GA 30333, USA. OI Mofenson, Lynne/0000-0002-2818-9808 NR 41 TC 375 Z9 381 U1 1 U2 14 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD NOV PY 1990 VL 162 IS 5 BP 1036 EP 1042 PG 7 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EE046 UT WOS:A1990EE04600006 PM 2230231 ER PT J AU TAUXE, RV PUHR, ND WELLS, JG HARGRETTBEAN, N BLAKE, PA AF TAUXE, RV PUHR, ND WELLS, JG HARGRETTBEAN, N BLAKE, PA TI ANTIMICROBIAL RESISTANCE OF SHIGELLA ISOLATES IN THE USA - THE IMPORTANCE OF INTERNATIONAL TRAVELERS SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,STAT SERV ACT,ATLANTA,GA 30333. RP TAUXE, RV (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,ENTER DIS BRANCH,1-5428,MAIL STOP C-09,ATLANTA,GA 30333, USA. NR 22 TC 98 Z9 99 U1 0 U2 1 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD NOV PY 1990 VL 162 IS 5 BP 1107 EP 1111 PG 5 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EE046 UT WOS:A1990EE04600016 PM 2230237 ER PT J AU KRILOV, LR ANDERSON, LJ AF KRILOV, LR ANDERSON, LJ TI ANTIBODY-MEDIATED ENHANCEMENT OF RESPIRATORY SYNCYTIAL VIRUS-INFECTION - REPLY SO JOURNAL OF INFECTIOUS DISEASES LA English DT Letter C1 CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,ATLANTA,GA 30333. RP KRILOV, LR (reprint author), N SHORE UNIV HOSP,DEPT PEDIAT,DIV PEDIAT INFECT DIS,300 COMMUNITY DR,MANHASSET,NY 11030, USA. NR 3 TC 0 Z9 0 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD NOV PY 1990 VL 162 IS 5 BP 1211 EP 1211 PG 1 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EE046 UT WOS:A1990EE04600040 ER PT J AU MCQUILLAN, GM GUNTER, EW LANNOM, L AF MCQUILLAN, GM GUNTER, EW LANNOM, L TI FIELD ISSUES FOR THE PLAN AND OPERATION OF THE LABORATORY COMPONENT OF THE 3RD NATIONAL-HEALTH AND NUTRITION EXAMINATION SURVEY SO JOURNAL OF NUTRITION LA English DT Article; Proceedings Paper CT CONF ON NUTRITION MONITORING AND NUTRITION STATUS ASSESSMENT CY DEC 08-10, 1989 CL CHARLESTON, SC C1 WESTAT CORP,ROCKVILLE,MD. CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV ENVIRONM HLTH LAB SCI,ATLANTA,GA 30333. RP MCQUILLAN, GM (reprint author), CTR DIS CONTROL,NATL CTR HLTH STAT,DIV HLTH EXAMINAT STAT,HYATTSVILLE,MD 20782, USA. NR 3 TC 10 Z9 10 U1 0 U2 0 PU AMER INST NUTRITION PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 0022-3166 J9 J NUTR JI J. Nutr. PD NOV PY 1990 VL 120 IS 11 SU S BP 1446 EP 1450 PG 5 WC Nutrition & Dietetics SC Nutrition & Dietetics GA EL483 UT WOS:A1990EL48300005 PM 2243285 ER PT J AU GUNTER, EW MCQUILLAN, G AF GUNTER, EW MCQUILLAN, G TI QUALITY-CONTROL IN PLANNING AND OPERATING THE LABORATORY COMPONENT FOR THE 3RD NATIONAL-HEALTH AND NUTRITION EXAMINATION SURVEY SO JOURNAL OF NUTRITION LA English DT Article; Proceedings Paper CT CONF ON NUTRITION MONITORING AND NUTRITION STATUS ASSESSMENT CY DEC 08-10, 1989 CL CHARLESTON, SC C1 CTR DIS CONTROL,NATL CTR HLTH STAT,DIV HLTH EXAMINAT STAT,ATLANTA,GA 30333. RP GUNTER, EW (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV ENVIRONM HLTH LAB SCI,ATLANTA,GA 30333, USA. NR 10 TC 18 Z9 18 U1 0 U2 0 PU AMER INST NUTRITION PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 0022-3166 J9 J NUTR JI J. Nutr. PD NOV PY 1990 VL 120 IS 11 SU S BP 1451 EP 1454 PG 4 WC Nutrition & Dietetics SC Nutrition & Dietetics GA EL483 UT WOS:A1990EL48300006 PM 2243286 ER PT J AU TROWBRIDGE, FL WONG, FL BYERS, TE SERDULA, MK AF TROWBRIDGE, FL WONG, FL BYERS, TE SERDULA, MK TI METHODOLOGICAL ISSUES IN NUTRITION SURVEILLANCE - THE CDC EXPERIENCE SO JOURNAL OF NUTRITION LA English DT Article; Proceedings Paper CT CONF ON NUTRITION MONITORING AND NUTRITION STATUS ASSESSMENT CY DEC 08-10, 1989 CL CHARLESTON, SC C1 CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,FIELD SERV BRANCH,ATLANTA,GA 30333. CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,EPIDEMIOL BRANCH,ATLANTA,GA 30333. RP TROWBRIDGE, FL (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV NUTR,ATLANTA,GA 30333, USA. NR 8 TC 6 Z9 6 U1 0 U2 1 PU AMER INST NUTRITION PI BETHESDA PA 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 SN 0022-3166 J9 J NUTR JI J. Nutr. PD NOV PY 1990 VL 120 IS 11 SU S BP 1512 EP 1518 PG 7 WC Nutrition & Dietetics SC Nutrition & Dietetics GA EL483 UT WOS:A1990EL48300018 PM 2173743 ER PT J AU STEENLAND, K BEAUMONT, J SPAETH, S BROWN, D OKUN, A JURCENKO, L RYAN, B PHILLIPS, S ROSCOE, R STAYNER, L MORRIS, J AF STEENLAND, K BEAUMONT, J SPAETH, S BROWN, D OKUN, A JURCENKO, L RYAN, B PHILLIPS, S ROSCOE, R STAYNER, L MORRIS, J TI NEW DEVELOPMENTS IN THE LIFE TABLE ANALYSIS SYSTEM OF THE NATIONAL-INSTITUTE-FOR-OCCUPATIONAL-SAFETY-AND-HEALTH SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE LA English DT Article RP STEENLAND, K (reprint author), NIOSH,IND WIDE STUDIES BRANCH,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 11 TC 104 Z9 105 U1 0 U2 4 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 1076-2752 J9 J OCCUP ENVIRON MED JI J. Occup. Environ. Med. PD NOV PY 1990 VL 32 IS 11 BP 1091 EP 1098 DI 10.1097/00043764-199011000-00008 PG 8 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EH611 UT WOS:A1990EH61100003 PM 2258764 ER PT J AU MEISSNER, C REIMER, CB BLACK, C BROOME, C RABSON, A SIBER, GR DELANEY, N CONNORS, M AMBROSINO, DM AF MEISSNER, C REIMER, CB BLACK, C BROOME, C RABSON, A SIBER, GR DELANEY, N CONNORS, M AMBROSINO, DM TI INTERPRETATION OF IGG SUBCLASS VALUES - A COMPARISON OF 2 ASSAYS SO JOURNAL OF PEDIATRICS LA English DT Article C1 HARVARD UNIV, SCH MED,DANA FARBER CANC INST,INFECT DIS LAB, 44 BINNEY ST, BOSTON, MA 02115 USA. MASSACHUSETTS PUBL HLTH BIOL LABS, BOSTON, MA USA. NEW ENGLAND MED CTR, DEPT PEDIAT & PATHOL, BOSTON, MA 02111 USA. CTR DIS CONTROL, CTR INFECT DIS, DIV IMMUNOL ONCOL & HEMATOL DIS, ATLANTA, GA 30333 USA. CTR DIS CONTROL, DIV BACTERIAL DIS, ATLANTA, GA 30333 USA. FU NIAID NIH HHS [AI 18125, AI 24659] NR 21 TC 19 Z9 19 U1 0 U2 0 PU MOSBY-ELSEVIER PI NEW YORK PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA SN 0022-3476 EI 1097-6833 J9 J PEDIATR-US JI J. Pediatr. PD NOV PY 1990 VL 117 IS 5 BP 726 EP 731 DI 10.1016/S0022-3476(05)83328-1 PG 6 WC Pediatrics SC Pediatrics GA EH439 UT WOS:A1990EH43900008 PM 2121946 ER PT J AU FIELDS, BS NERAD, TA SAWYER, TK KING, CH BARBAREE, JM MARTIN, WT MORRILL, WE SANDEN, GN AF FIELDS, BS NERAD, TA SAWYER, TK KING, CH BARBAREE, JM MARTIN, WT MORRILL, WE SANDEN, GN TI CHARACTERIZATION OF AN AXENIC STRAIN OF HARTMANNELLA-VERMIFORMIS OBTAINED FROM AN INVESTIGATION OF NOSOCOMIAL LEGIONELLOSIS SO JOURNAL OF PROTOZOOLOGY LA English DT Article DE AMEBAS; HARTMANNELLA-VERMIFORMIS; ISOENZYME PATTERNS; LEGIONELLOSIS ID STARCH-GEL ELECTROPHORESIS; PATHOGENIC NAEGLERIA; PNEUMOPHILA; AMEBAS; WATER; ACANTHAMOEBA; VIRULENCE AB A free-living amoeba identified as Hartmannella vermiformis was isolated from a water sample obtained during an investigation of nosocomial legionellosis. Hartmannella vermiformis is known to support the intracellular multiplication of Legionella pneumophila. This strain of H. vermiformis, designated CDC-19, was cloned and established in axenic culture to develop a model for the study of the pathogenicity of legionellae. Isoenzyme patterns of axenically-cultivated strain CDC-19 were compared with two strains of H. vermiformis derived from the type strain, one axenic (ATCC 50236) and the other grown in the presence of bacteria (ATCC 30966). Enzyme patterns suggested that all three strains are assignable to the species H. vermiformis. Axenic H. vermiformis strain CDC-19 has been deposited with the American Type Culture Collection (ATCC 50237) and should prove useful in the study of protozoan-bacterial interaction. C1 RESCON ASSOCIATES INC,ROYAL OAK,MD 21662. UNIV GEORGIA,COLL VET MED,DEPT MED MICROBIOL,ATHENS,GA 30602. AMER TYPE CULTURE COLLECT,ROCKVILLE,MD 20852. RP FIELDS, BS (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,RESP DIS BRANCH,ATLANTA,GA 30333, USA. NR 25 TC 54 Z9 55 U1 1 U2 3 PU SOC PROTOZOOLOGISTS PI LAWRENCE PA 810 E 10TH ST, LAWRENCE, KS 66044 SN 0022-3921 J9 J PROTOZOOL PD NOV-DEC PY 1990 VL 37 IS 6 BP 581 EP 583 DI 10.1111/j.1550-7408.1990.tb01269.x PG 3 WC Zoology SC Zoology GA ER164 UT WOS:A1990ER16400025 PM 2086787 ER PT J AU LAUER, CG REID, TJ WIDEMAN, CS EVATT, BL ALVING, BM AF LAUER, CG REID, TJ WIDEMAN, CS EVATT, BL ALVING, BM TI FREE PROTEIN-S DEFICIENCY IN A FAMILY WITH VENOUS THROMBOSIS SO JOURNAL OF VASCULAR SURGERY LA English DT Article C1 WALTER REED ARMY MED CTR,DEPT HEMATOL,WASHINGTON,DC 20307. WALTER REED ARMY MED CTR,DEPT VASC SURG,WASHINGTON,DC 20307. CTR DIS CONTROL,DIV IMMUNOL ONCOL & HEMATOL DIS,ATLANTA,GA 30333. NR 18 TC 5 Z9 5 U1 0 U2 0 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0741-5214 J9 J VASC SURG JI J. Vasc. Surg. PD NOV PY 1990 VL 12 IS 5 BP 541 EP 544 PG 4 WC Surgery; Peripheral Vascular Disease SC Surgery; Cardiovascular System & Cardiology GA EJ687 UT WOS:A1990EJ68700006 PM 2146406 ER PT J AU ALTER, MJ MARGOLIS, HS AF ALTER, MJ MARGOLIS, HS TI THE EMERGENCE OF HEPATITIS-B AS A SEXUALLY-TRANSMITTED DISEASE SO MEDICAL CLINICS OF NORTH AMERICA LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,ATLANTA,GA 30333. NR 62 TC 46 Z9 47 U1 1 U2 1 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0025-7125 J9 MED CLIN N AM JI Med. Clin. N. Am. PD NOV PY 1990 VL 74 IS 6 BP 1529 EP 1541 PG 13 WC Medicine, General & Internal SC General & Internal Medicine GA EM096 UT WOS:A1990EM09600011 PM 2246951 ER PT J AU SCHMID, GP AF SCHMID, GP TI APPROACH TO THE PATIENT WITH GENITAL ULCER DISEASE SO MEDICAL CLINICS OF NORTH AMERICA LA English DT Article C1 MOREHOUSE SCH MED,MED,ATLANTA,GA. CTR DIS CONTROL,CTR PREVENT SERV,DIV STD HIV PREVENT,CLIN RES BRANCH,ATLANTA,GA 30333. RP SCHMID, GP (reprint author), CTR DIS CONTROL,TECH INFORMAT SERV E06,ATLANTA,GA 30333, USA. NR 44 TC 10 Z9 10 U1 0 U2 0 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0025-7125 J9 MED CLIN N AM JI Med. Clin. N. Am. PD NOV PY 1990 VL 74 IS 6 BP 1559 EP 1572 PG 14 WC Medicine, General & Internal SC General & Internal Medicine GA EM096 UT WOS:A1990EM09600013 PM 2246953 ER PT J AU PETERSON, HB GALAID, EI CATES, W AF PETERSON, HB GALAID, EI CATES, W TI PELVIC INFLAMMATORY DISEASE SO MEDICAL CLINICS OF NORTH AMERICA LA English DT Article C1 CTR DIS CONTROL,WOMENS HLTH & FERTIL BRANCH,DIV REPROD HLTH,ATLANTA,GA 30333. CTR DIS CONTROL,DIV STD HIV PREVENT,ATLANTA,GA 30333. CTR DIS CONTROL,CTR PREVENT SERV,ATLANTA,GA 30333. RP PETERSON, HB (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV REPROD HLTH,ATLANTA,GA 30333, USA. NR 45 TC 12 Z9 12 U1 0 U2 0 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0025-7125 J9 MED CLIN N AM JI Med. Clin. N. Am. PD NOV PY 1990 VL 74 IS 6 BP 1603 EP 1615 PG 13 WC Medicine, General & Internal SC General & Internal Medicine GA EM096 UT WOS:A1990EM09600015 PM 2246955 ER PT J AU LAL, AA GOLDMAN, IF CAMPBELL, GH AF LAL, AA GOLDMAN, IF CAMPBELL, GH TI PRIMARY STRUCTURE OF THE 25-KILODALTON OOKINETE ANTIGEN FROM PLASMODIUM-REICHENOWI SO MOLECULAR AND BIOCHEMICAL PARASITOLOGY LA English DT Note RP LAL, AA (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,MALARIA BRANCH,MAIL STOP F12,ATLANTA,GA 30333, USA. FU PHS HHS [1-Y02-00006-01] NR 8 TC 21 Z9 22 U1 0 U2 0 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0166-6851 J9 MOL BIOCHEM PARASIT JI Mol. Biochem. Parasitol. PD NOV PY 1990 VL 43 IS 1 BP 143 EP 146 DI 10.1016/0166-6851(90)90139-D PG 4 WC Biochemistry & Molecular Biology; Parasitology SC Biochemistry & Molecular Biology; Parasitology GA ED881 UT WOS:A1990ED88100015 PM 2290442 ER PT J AU EKBOM, A HELMICK, C ZACK, M ADAMI, HO AF EKBOM, A HELMICK, C ZACK, M ADAMI, HO TI ULCERATIVE-COLITIS AND COLORECTAL-CANCER - A POPULATION-BASED STUDY SO NEW ENGLAND JOURNAL OF MEDICINE LA English DT Article C1 UNIV HOSP UPPSALA,CANC EPIDEMIOL UNIT,S-75185 UPPSALA,SWEDEN. CTR DIS CONTROL,ATLANTA,GA 30333. RP EKBOM, A (reprint author), UNIV HOSP UPPSALA,DEPT SURG,S-75185 UPPSALA,SWEDEN. NR 30 TC 1081 Z9 1100 U1 2 U2 17 PU MASS MEDICAL SOC PI BOSTON PA 10 SHATTUCK, BOSTON, MA 02115 SN 0028-4793 J9 NEW ENGL J MED JI N. Engl. J. Med. PD NOV 1 PY 1990 VL 323 IS 18 BP 1228 EP 1233 DI 10.1056/NEJM199011013231802 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA EF254 UT WOS:A1990EF25400002 PM 2215606 ER PT J AU PLOTKIN, SA HALSEY, NA LEPOW, ML MARCUSE, EK MCCRACKEN, GH NANKERVIS, GA PHILLIPS, CF SCOTT, GB STEELE, RW WRIGHT, HT PETER, G HARDEGREE, C HINMAN, AR LAMONTAGNE, JR GOLD, R ORENSTEIN, W EASTON, JG DAUM, RS AF PLOTKIN, SA HALSEY, NA LEPOW, ML MARCUSE, EK MCCRACKEN, GH NANKERVIS, GA PHILLIPS, CF SCOTT, GB STEELE, RW WRIGHT, HT PETER, G HARDEGREE, C HINMAN, AR LAMONTAGNE, JR GOLD, R ORENSTEIN, W EASTON, JG DAUM, RS TI HAEMOPHILUS-INFLUENZAE TYPE-B CONJUGATE VACCINES - IMMUNIZATION OF CHILDREN AT 15 MONTHS OF AGE SO PEDIATRICS LA English DT Article C1 CTR DIS CONTROL,ATLANTA,GA 30333. RP PLOTKIN, SA (reprint author), US FDA,WASHINGTON,DC 20204, USA. RI Steele, Russell/A-6075-2011 NR 10 TC 1 Z9 1 U1 0 U2 0 PU AMER ACAD PEDIATRICS PI ELK GROVE VILLAGE PA 141 NORTH-WEST POINT BLVD, ELK GROVE VILLAGE, IL 60007-1098 SN 0031-4005 J9 PEDIATRICS JI Pediatrics PD NOV PY 1990 VL 86 IS 5 BP 794 EP 796 PG 3 WC Pediatrics SC Pediatrics GA EF347 UT WOS:A1990EF34700026 ER PT J AU KAUFFMAN, RE BANNER, W BLUMER, JL GORMAN, RL LAMBERT, GH SNODGRASS, W BENNETT, DR CORDERO, JF DOOLEY, S LICATA, SA PETERSON, R PETRICCIANI, JC TROENDLE, G AF KAUFFMAN, RE BANNER, W BLUMER, JL GORMAN, RL LAMBERT, GH SNODGRASS, W BENNETT, DR CORDERO, JF DOOLEY, S LICATA, SA PETERSON, R PETRICCIANI, JC TROENDLE, G TI CLIOQUINOL (IODOCHLORHYDROXYQUIN, VIOFORM) AND IODOQUINOL (DIIODOHYDROXYQUIN) - BLINDNESS AND NEUROPATHY SO PEDIATRICS LA English DT Article C1 AMER COLL OBSTET & GYNECOLOGISTS,WASHINGTON,DC. PHARMACEUT MANUFACTURERS ASSOC,WASHINGTON,DC. CTR DIS CONTROL,ATLANTA,GA 30333. HLTH & WELF CANADA,HLTH PROTECT BRANCH,OTTAWA K1A 0L2,ONTARIO,CANADA. US FDA,WASHINGTON,DC 20204. RP KAUFFMAN, RE (reprint author), AMER MED ASSOC,CHICAGO,IL 60610, USA. NR 13 TC 14 Z9 14 U1 0 U2 0 PU AMER ACAD PEDIATRICS PI ELK GROVE VILLAGE PA 141 NORTH-WEST POINT BLVD, ELK GROVE VILLAGE, IL 60007-1098 SN 0031-4005 J9 PEDIATRICS JI Pediatrics PD NOV PY 1990 VL 86 IS 5 BP 797 EP 798 PG 2 WC Pediatrics SC Pediatrics GA EF347 UT WOS:A1990EF34700027 ER PT J AU LAIRMORE, MD JACOBSON, S GRACIA, F DE, BK CASTILLO, L LARREATEGUI, M ROBERTS, BD LEVINE, PH BLATTNER, WA KAPLAN, JE AF LAIRMORE, MD JACOBSON, S GRACIA, F DE, BK CASTILLO, L LARREATEGUI, M ROBERTS, BD LEVINE, PH BLATTNER, WA KAPLAN, JE TI ISOLATION OF HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE-2 FROM GUAYMI INDIANS IN PANAMA SO PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,RETROVIRUS DIS BRANCH,ATLANTA,GA 30333. NIH,NEUROIMMUNOL BRANCH,BETHESDA,MD 20892. GORGAS MEM LAB,DIV EPIDEMIOL,PANAMA CITY,PANAMA. NCI,ENVIRONM EPIDEMIOL BRANCH,ROCKVILLE,MD 20852. FU NCI NIH HHS [NCI-CP-31015] NR 25 TC 178 Z9 179 U1 0 U2 1 PU NATL ACAD SCIENCES PI WASHINGTON PA 2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 SN 0027-8424 J9 P NATL ACAD SCI USA JI Proc. Natl. Acad. Sci. U. S. A. PD NOV PY 1990 VL 87 IS 22 BP 8840 EP 8844 DI 10.1073/pnas.87.22.8840 PG 5 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA EJ607 UT WOS:A1990EJ60700032 PM 2247455 ER PT J AU THACKER, SB GOODMAN, RA DICKER, RC AF THACKER, SB GOODMAN, RA DICKER, RC TI TRAINING AND SERVICE IN PUBLIC-HEALTH PRACTICE, 1951-90-CDC EPIDEMIC INTELLIGENCE SERVICE SO PUBLIC HEALTH REPORTS LA English DT Article AB The Epidemic Intelligence Service (EIS) was created at the Centers for Disease Control (CDC) in 1951 as a combined training and service program in the practice of applied epidemiology. Since 1951, more than 1,700 professional have served in this 2-year program of the Public Health Service. In the decade of the 1980s, EIS underwent dramatic changes in response to the increased breadth of the CDC mission and the rapid expansion of epidemiologic methods. Modifications in the experience of an EIS Officer have resulted from the increased need for more sophisticated analytic methods and the use of microcomputers, as well as CDC's expanded mission into chronic diseases, environmental health, occupational health, and injury control. Officers who have entered the EIS in the past decade tend to be older than their predecessors, tend to enter the program with more experience and training in epidemiology, and are more likely to stay in public health either at the Federal level or in State and local health departments. The EIS Program continues to be a critical source for men and women to respond to the need and demand for epidemiologic services both domestically and internationally. RP THACKER, SB (reprint author), CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,EIS OFF,MAIL STOP C08,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 9 TC 17 Z9 17 U1 0 U2 3 PU US GOVERNMENT PRINTING OFFICE PI WASHINGTON PA SUPT OF DOCUMENTS, WASHINGTON, DC 20402-9325 SN 0033-3549 J9 PUBLIC HEALTH REP JI Public Health Rep. PD NOV-DEC PY 1990 VL 105 IS 6 BP 599 EP 604 PG 6 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EP317 UT WOS:A1990EP31700009 PM 2175439 ER PT J AU GOODMAN, RA BAUMAN, CF GREGG, MB VIDETTO, JF STROUP, DF CHALMERS, NP AF GOODMAN, RA BAUMAN, CF GREGG, MB VIDETTO, JF STROUP, DF CHALMERS, NP TI EPIDEMIOLOGIC FIELD INVESTIGATIONS BY THE CENTERS FOR DISEASE-CONTROL AND EPIDEMIC INTELLIGENCE SERVICE, 1946-87 SO PUBLIC HEALTH REPORTS LA English DT Article AB The epidemiologic field investigation is an important tool used by the Centers for Disease Control (CDC) to provide assistance to State, local, and international public health agencies. The Epidemic Intelligence Service (EIS) of the CDC is an ongoing program that gives physicians and other health professionals opportunities to learn and practice epidemiology. In the period 1946-87, EIS Officers and other professional staff based at CDC headquarters participated in 2,900 epidemiologic field investigations requested by State, local, and international public health agencies. Nearly two-thirds of the investigations involved infectious disease problems, while 13 percent involved non-infectious conditions; for 21.1 percent, the etiology of the problem was unknown when the investigation was initiated. Among the specific subcategories, bacterial causes were the most common, accounting for 864 (29.8 percent) of all investigations. During this 41-year period, an increasing proportion of the field epidemiologic investigations involved public health problems of noninfectious etiology. Trends in the types of investigations done probably represent the influence of such factors as CDC's priorities, organizational structure, and budget; the size of the EIS Program; national health initiatives; and the States' needs and programs. RP GOODMAN, RA (reprint author), CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,MAIL STOP C08,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 4 TC 13 Z9 14 U1 0 U2 2 PU US GOVERNMENT PRINTING OFFICE PI WASHINGTON PA SUPT OF DOCUMENTS, WASHINGTON, DC 20402-9325 SN 0033-3549 J9 PUBLIC HEALTH REP JI Public Health Rep. PD NOV-DEC PY 1990 VL 105 IS 6 BP 604 EP 610 PG 7 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EP317 UT WOS:A1990EP31700010 PM 2175440 ER PT J AU ALEXANDER, PG JOHNSON, R WILLIAMS, WW HADLER, SC WHITE, JW COLEMAN, PJ AF ALEXANDER, PG JOHNSON, R WILLIAMS, WW HADLER, SC WHITE, JW COLEMAN, PJ TI HEPATITIS-B VACCINATION PROGRAMS FOR HEALTH-CARE PERSONNEL IN UNITED-STATES HOSPITALS SO PUBLIC HEALTH REPORTS LA English DT Article ID SEROEPIDEMIOLOGIC SURVEY; RURAL HOSPITALS; RISK; EMPLOYEES; INFECTION; VIRUS AB A random sample of 232 U.S. hospitals was surveyed. Of those hospitals, 75 percent had hepatitis B vaccination programs. The presence of a program was associated with hospital size (60 percent of those with 100 beds, 75 percent with 100-499 beds, 90 percent with 500 or more beds; P = 0.0013) and hospital location (urban 86 percent; rural 57 percent; P < 0.001). The frequency of needlestick exposures per month among hospital personnel and hospital location were directly related to and best predicted the existence of hepatitis B vaccination programs. All hospitals with programs offered vaccine to high-risk personnel (as defined by the hospital). Seventy-seven percent of hospitals paid all costs for vaccinating high-risk personnel; 19 percent paid for any employee to be vaccinated regardless of risk status. Forty-six percent of hospitals with programs were estimated to have vaccinated more than 10 percent of all eligible personnel, and 13 percent to have vaccinated more than 25 percent of eligible personnel. The highest compliance rates were associated with hospitals paying for the vaccine and requiring vaccination of high-risk personnel. Fifty-four percent of hospitals attributed noncompliance to concern regarding vaccine safety and effectiveness. The reasons why there was no vaccination program in 58 hospitals were (a) low incidence of hepatitis B virus infections among personnel, (b) cost of vaccine, and (c) vaccination being offered as part of a needlestick protocol. Full utilization of hepatitis B vaccine could eliminate the occupational hazard that hepatitis B virus presents to health care personnel. C1 CASE WESTERN RESERVE SCH MED,CLEVELAND,OH. CTR DIS CONTROL,CHILD & ADULT IMMUNIZAT SECT,SURVEILLANCE INVEST & RES BRANCH,ATLANTA,GA 30333. CTR DIS CONTROL,AGCY TOX SUBST & DIS REGISTRY,DIV HLTH STUDIES,ATLANTA,GA 30333. UNIV MICHIGAN,SCH PUBL HLTH,ANN ARBOR,MI 48109. CTR DIS CONTROL,CTR PREVENT SERV,DIV IMMUNIZAT,SIR BRANCH,ATLANTA,GA 30333. CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,HEPATITIS BRANCH,ATLANTA,GA 30333. NR 19 TC 14 Z9 15 U1 0 U2 1 PU US GOVERNMENT PRINTING OFFICE PI WASHINGTON PA SUPT OF DOCUMENTS, WASHINGTON, DC 20402-9325 SN 0033-3549 J9 PUBLIC HEALTH REP JI Public Health Rep. PD NOV-DEC PY 1990 VL 105 IS 6 BP 610 EP 616 PG 7 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EP317 UT WOS:A1990EP31700011 PM 2148012 ER PT J AU KHARDORI, N ELTING, L WONG, E SCHABLE, B BODEY, GP AF KHARDORI, N ELTING, L WONG, E SCHABLE, B BODEY, GP TI NOSOCOMIAL INFECTIONS DUE TO XANTHOMONAS-MALTOPHILIA (PSEUDOMONAS-MALTOPHILIA) IN PATIENTS WITH CANCER SO REVIEWS OF INFECTIOUS DISEASES LA English DT Article C1 UNIV TEXAS,MD ANDERSON CANCER CTR,DEPT MED SPECIALTIES,INFECT DIS SECT,HOUSTON,TX 77030. CTR DIS CONTROL,CTR INFECT DIS,ATLANTA,GA 30333. NR 28 TC 160 Z9 161 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0162-0886 J9 REV INFECT DIS PD NOV-DEC PY 1990 VL 12 IS 6 BP 997 EP 1003 PG 7 WC Immunology; Microbiology SC Immunology; Microbiology GA EK511 UT WOS:A1990EK51100003 PM 2267495 ER PT J AU CHACINBONILLA, L MATHEWS, H DIKDAN, Y GUANIPA, N AF CHACINBONILLA, L MATHEWS, H DIKDAN, Y GUANIPA, N TI A SEROPIDEMIOLOGICAL STUDY OF AMEBIASIS IN A COMMUNITY OF ZULIA STATE, VENEZUELA SO REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO LA Spanish DT Article ID ENDEMIC AMEBIASIS; SEROEPIDEMIOLOGY AB In the present evaluation, a community of low socioeconomical conditions from Zulia State, Venezuela, was analyzed for the prevalence of antibodies to E. histolytica. Two hundred and eighty three serum samples were collected and examined by the indirect hemagglutination test according to a microtiter modification of the KESSEL and LEWIS method, as used by MILGRAM et al. Antigen prepared from axenically-grown. E. histolytica strain HK9 in Diamond's medium was used. The seropositivity rate obtained was 46.6% and the frequency of positive cases was dependent on age. The antibody profiles obtained suggest a high endemicity for this parasitic infection in the area studied, with a much higher level of transmission than invasive amebiasis. C1 CTR DIS CONTROL,ATLANTA,GA 30333. RP CHACINBONILLA, L (reprint author), UNIV ZULIA,INST INVEST CLIN,APARTADO 1151,MARACAIBO,VENEZUELA. NR 35 TC 6 Z9 7 U1 0 U2 2 PU INST MEDICINA TROPICAL PI SAO PAULO PA AV DR ENEIAS C AGUIAR CAIXA POSTAL 2921, SAO PAULO, BRAZIL SN 0036-4665 J9 REV I MED TROP PD NOV-DEC PY 1990 VL 32 IS 6 BP 467 EP 473 DI 10.1590/S0036-46651990000600013 PG 7 WC Tropical Medicine SC Tropical Medicine GA EU516 UT WOS:A1990EU51600013 PM 2135495 ER PT J AU LYNBERG, MC KHOURY, MJ LAMMER, EJ WALLER, KO CORDERO, JF ERICKSON, JD AF LYNBERG, MC KHOURY, MJ LAMMER, EJ WALLER, KO CORDERO, JF ERICKSON, JD TI SENSITIVITY, SPECIFICITY, AND POSITIVE PREDICTIVE VALUE OF MULTIPLE MALFORMATIONS IN ISOTRETINOIN EMBRYOPATHY SURVEILLANCE SO TERATOLOGY LA English DT Article C1 CALIF BIRTH DEFECTS MONITORING PROGRAM,EMERYVILLE,CA 94608. CALIF DEPT HLTH SERV,DIV FIELD SERV,EPIDEMIOL PROGRAM OFF,EMERYVILLE,CA 94608. RP LYNBERG, MC (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333, USA. NR 12 TC 37 Z9 40 U1 0 U2 1 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0040-3709 J9 TERATOLOGY JI Teratology PD NOV PY 1990 VL 42 IS 5 BP 513 EP 519 DI 10.1002/tera.1420420508 PG 7 WC Developmental Biology; Toxicology SC Developmental Biology; Toxicology GA EG979 UT WOS:A1990EG97900007 PM 2278026 ER PT J AU BURKOT, TR GARNER, P PARU, R DAGORO, H BARNES, A MCDOUGALL, S WIRTZ, RA CAMPBELL, G SPARK, R AF BURKOT, TR GARNER, P PARU, R DAGORO, H BARNES, A MCDOUGALL, S WIRTZ, RA CAMPBELL, G SPARK, R TI EFFECTS OF UNTREATED BED NETS ON THE TRANSMISSION OF PLASMODIUM-FALCIPARUM, PLASMODIUM-VIVAX AND WUCHERERIA-BANCROFTI IN PAPUA-NEW-GUINEA SO TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE LA English DT Article ID ANOPHELES-PUNCTULATUS COMPLEX; MOSQUITO-NETS; CIRCUMSPOROZOITE PROTEINS; MALARIA TRANSMISSION; RURAL AREA; ANTIBODIES; SPOROZOITES; VACCINE; GAMBIA; POPULATION AB The impact of untreated bed nets on the transmission of human malaria and filariasis in a village in a hyperendemic area of Papua New Guinea was studied. In anopheline mosquitoes, the Plasmodium falciparum sporozoite antigen positivity rate, filarial infection rates and human blood indices dropped significantly after bed nets were introduced. This reduction in human-vector contact did not affect mosquito density as no significant difference in either landing rates or indoor resting catches was found. The number of bed nets in a house and ownership of dogs were factors significantly associated with a reduction in the number of indoor resting mosquitoes. However, the reduction in the P. falciparum sporozoite antigen rate in mosquitoes was not accompanied by a reduction in either malaria parasite or antibody prevalences' or titres against the P. falciparum circumsporozoite protein. C1 PAPUA NEW GUINEA INST MED RES,MADANG,PAPUA N GUINEA. UNIV QUEENSLAND,SCH MED,TROP HLTH EDUC PROGRAM,BRISBANE,QLD 4000,AUSTRALIA. WALTER REED ARMY MED CTR,DEPT ENTOMOL,WASHINGTON,DC 20307. CTR DIS CONTROL,CTR INFECT DIS,MALARIA BRANCH,ATLANTA,GA 30333. PAPUA NEW GUINEA INST MED RES,GOROKA,PAPUA N GUINEA. RP BURKOT, TR (reprint author), QUEENSLAND INST MED RES,TROP HLTH PROGRAM,BRAMSTON TERRACE,BRISBANE 4006,AUSTRALIA. RI Burkot, Thomas/C-6838-2013 NR 37 TC 42 Z9 42 U1 0 U2 1 PU ROYAL SOC TROPICAL MEDICINE PI LONDON PA MANSON HOUSE 26 PORTLAND PLACE, LONDON, ENGLAND W1N 4EY SN 0035-9203 J9 T ROY SOC TROP MED H JI Trans. Roy. Soc. Trop. Med. Hyg. PD NOV-DEC PY 1990 VL 84 IS 6 BP 773 EP 779 DI 10.1016/0035-9203(90)90073-N PG 7 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA ER998 UT WOS:A1990ER99800007 PM 2096502 ER PT J AU STAFFORD, RS AF STAFFORD, RS TI RECENT TRENDS IN CESAREAN-SECTION USE IN CALIFORNIA SO WESTERN JOURNAL OF MEDICINE LA English DT Article C1 UNIV CALIF SAN FRANCISCO,SCH MED,SAN FRANCISCO,CA 94143. CTR DIS CONTROL,ATLANTA,GA 30333. FU AHRQ HHS [HS-06116] NR 21 TC 16 Z9 18 U1 0 U2 0 PU CALIFORNIA PHYSICIAN MAGAZINE PI SAN FRANCISCO PA C/O DONNA TAYLOR, EDITOR, PO BOX 7690, SAN FRANCISCO, CA 94102-7690 SN 0093-0415 J9 WESTERN J MED JI West. J. Med. PD NOV PY 1990 VL 153 IS 5 BP 511 EP 514 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA EH946 UT WOS:A1990EH94600004 PM 2260286 ER PT J AU MURPHY, FA AF MURPHY, FA TI CONTEXT FOR MODERN VACCINE DEVELOPMENT SO ZHURNAL MIKROBIOLOGII EPIDEMIOLOGII I IMMUNOBIOLOGII LA Russian DT Article RP MURPHY, FA (reprint author), CTR DIS CONTROL,CTR INFECT DIS,ATLANTA,GA 30333, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU GOSUDARSTVENNOE IZDATELSTVO PI MOSCOW PA MEDITSINSKOI LITERATURY PETROVKA 12, MOSCOW, RUSSIA SN 0372-9311 J9 ZH MIKROB EPID IMMUN PD NOV PY 1990 IS 11 BP 83 EP 90 PG 8 WC Infectious Diseases SC Infectious Diseases GA EN395 UT WOS:A1990EN39500022 PM 2097852 ER PT J AU ROPER, WL AF ROPER, WL TI FILOVIRUS INFECTION IN NEWLY IMPORTED MONKEYS SO SCIENCE LA English DT Letter RP ROPER, WL (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 6 TC 0 Z9 0 U1 0 U2 0 PU AMER ASSOC ADVANCEMENT SCIENCE PI WASHINGTON PA 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005 SN 0036-8075 J9 SCIENCE JI Science PD OCT 26 PY 1990 VL 250 IS 4980 BP 492 EP 492 DI 10.1126/science.2237399 PG 1 WC Multidisciplinary Sciences SC Science & Technology - Other Topics GA EE660 UT WOS:A1990EE66000003 PM 2237399 ER PT J AU CUMMINS, D MCCORMICK, JB BENNETT, D SAMBA, JA FARRAR, B MACHIN, SJ FISHERHOCH, SP AF CUMMINS, D MCCORMICK, JB BENNETT, D SAMBA, JA FARRAR, B MACHIN, SJ FISHERHOCH, SP TI ACUTE SENSORINEURAL DEAFNESS IN LASSA FEVER SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 CTR DIS CONTROL,DIV VIRAL DIS,SPECIAL PATHOGENS BRANCH,ATLANTA,GA 30333. UNIV COLL & MIDDLESEX SCH MED,DEPT HEMATOL,LONDON,ENGLAND. NIXON METHODIST MEM HOSP,SEGBWEMA,SIERRA LEONE. LASSA FEVER RES PROJECT,SEGBWEMA,SIERRA LEONE. NATL DIAMOND MIN CORP HOSP,TONGO,SIERRA LEONE. FU Wellcome Trust NR 24 TC 45 Z9 46 U1 1 U2 3 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD OCT 24 PY 1990 VL 264 IS 16 BP 2093 EP 2096 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA ED480 UT WOS:A1990ED48000045 PM 2214077 ER PT J AU AGOCS, MM ETZEL, RA PARRISH, RG PASCHAL, DC CAMPAGNA, PR COHEN, DS KILBOURNE, EM HESSE, JL AF AGOCS, MM ETZEL, RA PARRISH, RG PASCHAL, DC CAMPAGNA, PR COHEN, DS KILBOURNE, EM HESSE, JL TI MERCURY EXPOSURE FROM INTERIOR LATEX PAINT SO NEW ENGLAND JOURNAL OF MEDICINE LA English DT Article C1 CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV ENVIRONM HAZARDS & HLTH EFFECTS,ATLANTA,GA 30306. MICHIGAN DEPT PUBL HLTH,CTR ENVIRONM HLTH SCI,LANSING,MI 48909. US EPA,ENVIRONM RESPONSE BRANCH,EDISON,NJ. CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV ENVIRONM HLTH LAB SCI,ATLANTA,GA 30306. UNIV CALIF SAN DIEGO,SCH MED,LA JOLLA,CA 92093. NR 40 TC 60 Z9 61 U1 0 U2 3 PU MASS MEDICAL SOC PI BOSTON PA 10 SHATTUCK, BOSTON, MA 02115 SN 0028-4793 J9 NEW ENGL J MED JI N. Engl. J. Med. PD OCT 18 PY 1990 VL 323 IS 16 BP 1096 EP 1101 DI 10.1056/NEJM199010183231603 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA ED527 UT WOS:A1990ED52700003 PM 2215577 ER PT J AU HOLMES, GP MCCORMICK, JB TROCK, SC CHASE, RA LEWIS, SM MASON, CA HALL, PA BRAMMER, LS PEREZORONOZ, GI MCDONNELL, MK PAULISSEN, JP SCHONBERGER, LB FISHERHOCH, SP AF HOLMES, GP MCCORMICK, JB TROCK, SC CHASE, RA LEWIS, SM MASON, CA HALL, PA BRAMMER, LS PEREZORONOZ, GI MCDONNELL, MK PAULISSEN, JP SCHONBERGER, LB FISHERHOCH, SP TI LASSA FEVER IN THE UNITED-STATES - INVESTIGATION OF A CASE AND NEW GUIDELINES FOR MANAGEMENT SO NEW ENGLAND JOURNAL OF MEDICINE LA English DT Note C1 CTR DIS CONTROL,EPIDEMIOLOGY PROGRAM OFF,DIV FIELD SERV,ATLANTA,GA 30333. ILLINOIS DEPT PUBL HLTH,SPRINGFIELD,IL. CENT DUPAGE HOSP,WINFIELD,IL. DUPAGE CTY HLTH DEPT,WHEATON,IL. RP HOLMES, GP (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,SPECIAL PATHOGENS BRANCH,ATLANTA,GA 30333, USA. NR 13 TC 89 Z9 94 U1 0 U2 1 PU MASS MEDICAL SOC PI BOSTON PA 10 SHATTUCK, BOSTON, MA 02115 SN 0028-4793 J9 NEW ENGL J MED JI N. Engl. J. Med. PD OCT 18 PY 1990 VL 323 IS 16 BP 1120 EP 1123 DI 10.1056/NEJM199010183231607 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA ED527 UT WOS:A1990ED52700007 PM 2215580 ER PT J AU KHAN, JA ADDISS, DG RIZWANULLAH AF KHAN, JA ADDISS, DG RIZWANULLAH TI PNEUMONIA AND COMMUNITY-HEALTH WORKERS SO LANCET LA English DT Letter C1 CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,ATLANTA,GA 30333. RP KHAN, JA (reprint author), AYUB MED COLL,PAKISTAN MED RES COUNCIL,ABBOTTABAD,PAKISTAN. NR 3 TC 0 Z9 0 U1 0 U2 0 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD OCT 13 PY 1990 VL 336 IS 8720 BP 939 EP 939 DI 10.1016/0140-6736(90)92307-4 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EC456 UT WOS:A1990EC45600037 PM 1976947 ER PT J AU WELLS, DL BUFF, E LEWIS, AL CALDER, RA AF WELLS, DL BUFF, E LEWIS, AL CALDER, RA TI ARBOVIRAL SURVEILLANCE - FLORIDA, 1990 (REPRINTED FROM THE MORBIDITY AND MORTALITY WEEKLY REPORT, VOL 39, PG 650-651, 1990) SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,DIV FIELD SERV,ATLANTA,GA 30333. RP WELLS, DL (reprint author), FLORIDA DEPT HLTH & REHAB SERV,DIV VECTOR BORNE INFECT DIS,CTR INFECT DIS,GAINESVILLE,FL, USA. NR 5 TC 0 Z9 0 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD OCT 10 PY 1990 VL 264 IS 14 BP 1805 EP 1805 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EB429 UT WOS:A1990EB42900009 ER PT J AU GREEN, CR FISHBEIN, D GLEIBERMAN, I AF GREEN, CR FISHBEIN, D GLEIBERMAN, I TI BRILL-ZINSSER - STILL WITH US SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Letter C1 N RIDGE GEN HOSP,FT LAUDERDALE,FL. RP GREEN, CR (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 3 TC 13 Z9 14 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD OCT 10 PY 1990 VL 264 IS 14 BP 1811 EP 1812 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA EB429 UT WOS:A1990EB42900024 PM 2119438 ER PT J AU MCCANCE, CR AF MCCANCE, CR TI TRAVELERS IMMUNIZATIONS - REPLY SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Letter RP MCCANCE, CR (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD OCT 10 PY 1990 VL 264 IS 14 BP 1812 EP 1812 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA EB429 UT WOS:A1990EB42900026 ER PT J AU MASTRO, TD FARLEY, TA ELLIOTT, JA FACKLAM, RR PERKS, JR HADLER, JL GOOD, RC SPIKA, JS AF MASTRO, TD FARLEY, TA ELLIOTT, JA FACKLAM, RR PERKS, JR HADLER, JL GOOD, RC SPIKA, JS TI AN OUTBREAK OF SURGICAL-WOUND INFECTIONS DUE TO GROUP-A STREPTOCOCCUS CARRIED ON THE SCALP SO NEW ENGLAND JOURNAL OF MEDICINE LA English DT Note C1 CTR DIS CONTROL,DIV FIELD SERV,EPIDEMIOL PROGRAM OFF,ATLANTA,GA 30333. CONNECTICUT DEPT HLTH SERV,HARTFORD,CT. RP MASTRO, TD (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV INTERNAL MED 2,RESP DIS BRANCH,MAILSTOP C09,ATLANTA,GA 30333, USA. NR 24 TC 58 Z9 58 U1 0 U2 1 PU MASS MEDICAL SOC PI BOSTON PA 10 SHATTUCK, BOSTON, MA 02115 SN 0028-4793 J9 NEW ENGL J MED JI N. Engl. J. Med. PD OCT 4 PY 1990 VL 323 IS 14 BP 968 EP 972 DI 10.1056/NEJM199010043231406 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA EA846 UT WOS:A1990EA84600006 PM 2205801 ER PT J AU TOOMEY, KE AF TOOMEY, KE TI HIV-INFECTION - THE DILEMMA OF PATIENT CONFIDENTIALITY SO AMERICAN FAMILY PHYSICIAN LA English DT Editorial Material RP TOOMEY, KE (reprint author), CTR DIS CONTROL,DIV STD HIV PREVENT,ATLANTA,GA 30333, USA. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER ACAD FAMILY PHYSICIANS PI KANSAS CITY PA 8880 WARD PARKWAY, KANSAS CITY, MO 64114-2797 SN 0002-838X J9 AM FAM PHYSICIAN JI Am. Fam. Physician PD OCT PY 1990 VL 42 IS 4 BP 955 EP & PG 0 WC Primary Health Care; Medicine, General & Internal SC General & Internal Medicine GA EB625 UT WOS:A1990EB62500003 PM 2220521 ER PT J AU FREEDMAN, DS STROGATZ, DS EAKER, E JOESOEF, MR DESTEFANO, F AF FREEDMAN, DS STROGATZ, DS EAKER, E JOESOEF, MR DESTEFANO, F TI DIFFERENCES BETWEEN BLACK-AND-WHITE MEN IN CORRELATES OF HIGH-DENSITY-LIPOPROTEIN CHOLESTEROL SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Article C1 CTR DIS CONTROL,CTR PREVENT SERV,ATLANTA,GA 30333. SUNY ALBANY,NEW YORK STATE DEPT HLTH,SCH PUBL HLTH,DEPT EPIDEMIOL,ALBANY,NY 12222. CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,ATLANTA,GA 30333. RP FREEDMAN, DS (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,AGENT ORANGE PROJECTS,F16,ATLANTA,GA 30333, USA. NR 47 TC 27 Z9 27 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 656 EP 669 PG 14 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400006 PM 2403106 ER PT J AU BECKSAGUE, CM JARVIS, WR BROOK, JH CULVER, DH POTTS, A GAY, E SHOTTS, BW HILL, B ANDERSON, RL WEINSTEIN, MP AF BECKSAGUE, CM JARVIS, WR BROOK, JH CULVER, DH POTTS, A GAY, E SHOTTS, BW HILL, B ANDERSON, RL WEINSTEIN, MP TI EPIDEMIC BACTEREMIA DUE TO ACINETOBACTER-BAUMANNII IN 5 INTENSIVE-CARE UNITS SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Article C1 STATE DEPT HLTH,TRENTON,NJ. UNIV MED & DENT NEW JERSEY,DEPT COMMUNITY HLTH,NEW BRUNSWICK,NJ 08903. UNIV MED & DENT NEW JERSEY,DEPT MED,NEW BRUNSWICK,NJ 08903. UNIV MED & DENT NEW JERSEY,DEPT PATHOL,NEW BRUNSWICK,NJ 08903. RP BECKSAGUE, CM (reprint author), CTR DIS CONTROL,CTR INFECT DIS,HOSP INFECT PROGRAM,ATLANTA,GA 30333, USA. NR 34 TC 148 Z9 154 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 723 EP 733 PG 11 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400013 PM 2403113 ER PT J AU BRANCHE, C SATTIN, R DEVITO, C RODRIGUEZ, J AF BRANCHE, C SATTIN, R DEVITO, C RODRIGUEZ, J TI PSYCHOACTIVE MEDICATIONS AND THE RISK OF HIP FRACTURE AMONG THE ELDERLY SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 1 Z9 1 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 754 EP 754 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400024 ER PT J AU SINKS, T SMITH, AB STEELE, GK RINSKY, R WATKINS, K AF SINKS, T SMITH, AB STEELE, GK RINSKY, R WATKINS, K TI A RETROSPECTIVE COHORT MORTALITY STUDY OF WORKERS AT A CAPACITOR PLANT UTILIZING POLYCHLORINATED-BIPHENYLS (PCBS) SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 NIOSH,CINCINNATI,OH 45208. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 755 EP 756 PG 2 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400029 ER PT J AU WILCOX, LS MARTINEZSCHNELL, B PETERSON, HB HUGHES, J AF WILCOX, LS MARTINEZSCHNELL, B PETERSON, HB HUGHES, J TI RISK-FACTORS FOR HYSTERECTOMY AFTER TUBAL-STERILIZATION SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 758 EP 759 PG 2 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400040 ER PT J AU YOUNG, P SAFTLAS, A ATRASH, H LAWSON, H AF YOUNG, P SAFTLAS, A ATRASH, H LAWSON, H TI NATIONAL TRENDS IN THE MANAGEMENT OF TUBAL PREGNANCY, 1970-1987 SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 1 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 759 EP 759 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400041 ER PT J AU ATRASH, H KOONIN, L LAWSON, H AF ATRASH, H KOONIN, L LAWSON, H TI MATERNAL MORTALITY IN THE UNITED-STATES, 1979-1986 SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 1 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 760 EP 760 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400045 ER PT J AU KAYE, WE LYBARGER, JA LOGUE, JN AF KAYE, WE LYBARGER, JA LOGUE, JN TI RECALL BIAS ASSOCIATED WITH PERCEIVED EXPOSURE TO HAZARDOUS SUBSTANCES SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 AGCY TOX SUBST & DIS REGISTRY,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 760 EP 760 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400047 ER PT J AU BOYLE, C KHOURY, MJ ANNEST, JL KRESNOW, M DESTEFANO, F AF BOYLE, C KHOURY, MJ ANNEST, JL KRESNOW, M DESTEFANO, F TI THE RELATION OF IMPAIRED FERTILITY IN MALES WITH COMPUTERIZED ANALYSIS OF SPERM MORPHOLOGY AND MOTILITY SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 762 EP 762 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400052 ER PT J AU LYNBERG, MC KHOURY, MJ BECERRA, JE AF LYNBERG, MC KHOURY, MJ BECERRA, JE TI CONTRIBUTION OF BIRTH-DEFECTS TO INFANT-MORTALITY AMONG LOW-BIRTH-WEIGHT INFANTS SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. RI Becerra, Jose/C-4071-2014 NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 762 EP 763 PG 2 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400055 ER PT J AU KHOURY, MJ CORDERO, JF PATTERSON, WD AF KHOURY, MJ CORDERO, JF PATTERSON, WD TI THE CHANGING EPIDEMIOLOGY OF NEURAL-TUBE DEFECTS, ATLANTA, GEORGIA, 1969-1988 SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 1 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 764 EP 764 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400060 ER PT J AU MILI, F KHOURY, MJ FLANDERS, WD GREENBERG, RS AF MILI, F KHOURY, MJ FLANDERS, WD GREENBERG, RS TI RISK OF CHILDHOOD-CANCER FOR INFANTS WITH BIRTH-DEFECTS - A RECORD-LINKAGE STUDY, 1968-1988 SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 1 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 764 EP 765 PG 2 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400063 ER PT J AU WINGO, PA LEE, NC ORY, HW BERAL, V PETERSON, HB RHODES, P AF WINGO, PA LEE, NC ORY, HW BERAL, V PETERSON, HB RHODES, P TI AGE-SPECIFIC DIFFERENCES IN THE RELATION BETWEEN ORAL-CONTRACEPTIVE USE AND BREAST-CANCER SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. RI Beral, Valerie/B-2979-2013 NR 0 TC 0 Z9 0 U1 0 U2 1 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 769 EP 769 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400081 ER PT J AU NAKASHIMA, AK ROLFS, RT SARASUA, S AF NAKASHIMA, AK ROLFS, RT SARASUA, S TI CHANGING PATTERNS IN RURAL AND URBAN DISTRIBUTION OF SYPHILIS SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 1 Z9 1 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 770 EP 771 PG 2 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400086 ER PT J AU NELSON, D SATTIN, R WINGO, P DEVITO, C AF NELSON, D SATTIN, R WINGO, P DEVITO, C TI ALCOHOL AND THE RISK OF FALL INJURY EVENTS AMONG THE ELDERLY SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 774 EP 775 PG 2 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400101 ER PT J AU IRWIN, K WEISS, N LEE, N PETERSON, H AF IRWIN, K WEISS, N LEE, N PETERSON, H TI TUBAL-STERILIZATION, HYSTERECTOMY, AND THE SUBSEQUENT OCCURRENCE OF EPITHELIAL OVARIAN-CANCER SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 2 Z9 2 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 777 EP 777 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400112 ER PT J AU SENIE, RT ROSEN, PP RHODES, P AF SENIE, RT ROSEN, PP RHODES, P TI THE IMPACT OF OBESITY ON DISEASE-FREE SURVIVAL AMONG 928 BREAST-CANCER PATIENTS AT 10 YEARS SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 782 EP 782 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400132 ER PT J AU DREWS, CD LYNBERG, MC AF DREWS, CD LYNBERG, MC TI EPIDEMIOLOGY OF CONGENITAL EYE DEFECTS SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. RI Drews-Botsch, Carolyn/M-8560-2016 OI Drews-Botsch, Carolyn/0000-0002-8763-7404 NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 796 EP 796 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400183 ER PT J AU SERDULA, M KOONG, SL WILLIAMSON, D MADANS, J ANDA, R KLEINMAN, J BYERS, T AF SERDULA, M KOONG, SL WILLIAMSON, D MADANS, J ANDA, R KLEINMAN, J BYERS, T TI ALCOHOL AND MORTALITY SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 797 EP 797 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400187 ER PT J AU HEATH, GW SHARLIN, KS FORD, ES WELTY, TK AF HEATH, GW SHARLIN, KS FORD, ES WELTY, TK TI HYPERTENSION AWARENESS AMONG SIOUX INDIANS IN SOUTH-DAKOTA SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 798 EP 798 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400192 ER PT J AU CASPERSEN, CJ BLOEMBERG, BPM SARIS, WHM MERRITT, RK KROMHOUT, D AF CASPERSEN, CJ BLOEMBERG, BPM SARIS, WHM MERRITT, RK KROMHOUT, D TI THE PREVALENCE OF PHYSICAL-ACTIVITY AND ITS ASSOCIATION WITH CORONARY HEART-DISEASE RISK-FACTORS IN ELDERLY MEN - THE ZUTPHEN STUDY - 1985 SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. RI Caspersen, Carl/B-2494-2009; Kromhout, Daan/A-8566-2014 NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 800 EP 800 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400200 ER PT J AU FORD, ES DESTEFANO, F AF FORD, ES DESTEFANO, F TI RISK-FACTORS FOR CORONARY HEART-DISEASE MORTALITY AMONG DIABETIC PERSONS SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 806 EP 806 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400223 ER PT J AU ANDREWS, JS ANDERSON, SE RIFENBURG, JA ROWLEY, DL KAHN, SE HUDSON, RF BURSE, VW NEEDHAM, LL LACHAPELLE, NC AF ANDREWS, JS ANDERSON, SE RIFENBURG, JA ROWLEY, DL KAHN, SE HUDSON, RF BURSE, VW NEEDHAM, LL LACHAPELLE, NC TI HEALTH-EFFECTS STUDY OF RESIDENTS NEAR THE HOLLYWOOD DUMPSITE, MEMPHIS, TENNESSEE SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. RI Needham, Larry/E-4930-2011 NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 809 EP 809 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400233 ER PT J AU WILLIAMSON, DF MADANS, J ANDA, RF KLEINMAN, J GIOVINO, G BYERS, T AF WILLIAMSON, DF MADANS, J ANDA, RF KLEINMAN, J GIOVINO, G BYERS, T TI SMOKING CESSATION AND THE SEVERITY OF WEIGHT-GAIN SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 813 EP 813 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400249 ER PT J AU LEE, NC RUBIN, GL GRIMES, DA AF LEE, NC RUBIN, GL GRIMES, DA TI MEASURES OF SEXUAL-BEHAVIOR AND THE RISK OF PELVIC INFLAMMATORY DISEASE SO AMERICAN JOURNAL OF EPIDEMIOLOGY LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU AMER J EPIDEMIOLOGY PI BALTIMORE PA 624 N BROADWAY RM 225, BALTIMORE, MD 21205 SN 0002-9262 J9 AM J EPIDEMIOL JI Am. J. Epidemiol. PD OCT PY 1990 VL 132 IS 4 BP 823 EP 823 PG 1 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EB314 UT WOS:A1990EB31400287 ER PT J AU RASMUSSEN, S MULINARE, J KHOURY, MJ AF RASMUSSEN, S MULINARE, J KHOURY, MJ TI SOME ISSUES IN THE STUDY OF BIRTH-DEFECTS AND RECURRENCE RISKS IN LIVE BIRTHS AND STILLBIRTHS - REPLY SO AMERICAN JOURNAL OF HUMAN GENETICS LA English DT Letter C1 CTR DIS CONTROL,ATLANTA,GA 30333. RP RASMUSSEN, S (reprint author), UNIV FLORIDA,COLL MED,GAINESVILLE,FL 32611, USA. NR 1 TC 0 Z9 0 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0002-9297 J9 AM J HUM GENET JI Am. J. Hum. Genet. PD OCT PY 1990 VL 47 IS 4 BP 742 EP 743 PG 2 WC Genetics & Heredity SC Genetics & Heredity GA EB319 UT WOS:A1990EB31900024 ER PT J AU KHOURY, MJ JAMES, LM ERICKSON, JD AF KHOURY, MJ JAMES, LM ERICKSON, JD TI ON THE MEASUREMENT AND INTERPRETATION OF BIRTH-DEFECT ASSOCIATIONS IN EPIDEMIOLOGIC STUDIES SO AMERICAN JOURNAL OF MEDICAL GENETICS LA English DT Article RP KHOURY, MJ (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333, USA. NR 26 TC 29 Z9 30 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0148-7299 J9 AM J MED GENET JI Am. J. Med. Genet. PD OCT PY 1990 VL 37 IS 2 BP 229 EP 236 DI 10.1002/ajmg.1320370213 PG 8 WC Genetics & Heredity SC Genetics & Heredity GA DZ792 UT WOS:A1990DZ79200012 PM 2248290 ER PT J AU CLASSEN, DC BURKE, JP FORD, CD EVERSHED, S ALOIA, MR WILFAHRT, JK ELLIOTT, JA AF CLASSEN, DC BURKE, JP FORD, CD EVERSHED, S ALOIA, MR WILFAHRT, JK ELLIOTT, JA TI STREPTOCOCCUS-MITIS SEPSIS IN BONE-MARROW TRANSPLANT PATIENTS RECEIVING ORAL ANTIMICROBIAL PROPHYLAXIS SO AMERICAN JOURNAL OF MEDICINE LA English DT Article C1 UNIV UTAH,SCH MED,SALT LAKE CITY,UT 84112. LATTER DAY ST HOSP,DIV ONCOL,SALT LAKE CITY,UT 84143. CTR DIS CONTROL,ATLANTA,GA 30333. RP CLASSEN, DC (reprint author), LATTER DAY ST HOSP,DIV INFECT DIS,8TH AVE & C ST,SALT LAKE CITY,UT 84143, USA. NR 23 TC 81 Z9 81 U1 0 U2 0 PU EXCERPTA MEDICA INC PI NEW YORK PA 245 WEST 17TH STREET, NEW YORK, NY 10011 SN 0002-9343 J9 AM J MED JI Am. J. Med. PD OCT PY 1990 VL 89 IS 4 BP 441 EP 446 DI 10.1016/0002-9343(90)90373-L PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA ED074 UT WOS:A1990ED07400008 PM 2171333 ER PT J AU ALTER, MJ MARGOLIS, HS AF ALTER, MJ MARGOLIS, HS TI MISUSE OF HEPATITIS-B VACCINE FOR PREEXPOSURE PROPHYLAXIS IN HEALTH-CARE WORKERS - REPLY SO AMERICAN JOURNAL OF MEDICINE LA English DT Letter RP ALTER, MJ (reprint author), CTR DIS CONTROL,ATLANTA,GA 30333, USA. NR 8 TC 0 Z9 0 U1 0 U2 0 PU EXCERPTA MEDICA INC PI NEW YORK PA 245 WEST 17TH STREET, NEW YORK, NY 10011 SN 0002-9343 J9 AM J MED JI Am. J. Med. PD OCT PY 1990 VL 89 IS 4 BP 543 EP 543 DI 10.1016/0002-9343(90)90396-U PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA ED074 UT WOS:A1990ED07400031 ER PT J AU FRANKS, AL BERAL, V CATES, W HOGUE, CJR AF FRANKS, AL BERAL, V CATES, W HOGUE, CJR TI CONTRACEPTION AND ECTOPIC PREGNANCY RISK SO AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY LA English DT Article C1 CTR DIS CONTROL,CTR PREVENT SERV,DIV SEXUALLY TRANSMITTED DIS,ATLANTA,GA 30333. RP FRANKS, AL (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV REPROD HLTH,OSA,ATLANTA,GA 30333, USA. RI Beral, Valerie/B-2979-2013 NR 17 TC 59 Z9 59 U1 0 U2 0 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0002-9378 J9 AM J OBSTET GYNECOL JI Am. J. Obstet. Gynecol. PD OCT PY 1990 VL 163 IS 4 BP 1120 EP 1123 PN 1 PG 4 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA EE716 UT WOS:A1990EE71600003 PM 2220914 ER PT J AU RODIS, JF QUINN, DL GARY, GW ANDERSON, LJ ROSENGREN, S CARTTER, ML CAMPBELL, WA VINTZILEOS, AM AF RODIS, JF QUINN, DL GARY, GW ANDERSON, LJ ROSENGREN, S CARTTER, ML CAMPBELL, WA VINTZILEOS, AM TI MANAGEMENT AND OUTCOMES OF PREGNANCIES COMPLICATED BY HUMAN B19 PARVOVIRUS INFECTION - A PROSPECTIVE-STUDY SO AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY LA English DT Article C1 UNIV CONNECTICUT,CTR HLTH,DEPT PEDIAT,DIV MED GENET,FARMINGTON,CT 06032. CTR DIS CONTROL,DIV VIRAL DIS,ATLANTA,GA 30333. CONNECTICUT DEPT HLTH SERV,HARTFORD,CT. RP RODIS, JF (reprint author), UNIV CONNECTICUT,CTR HLTH,DEPT OBSTET & GYNECOL,DIV MATERNAL FETAL MED,263 FARMINGTON AVE,FARMINGTON,CT 06032, USA. NR 14 TC 103 Z9 107 U1 0 U2 0 PU MOSBY-YEAR BOOK INC PI ST LOUIS PA 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 SN 0002-9378 J9 AM J OBSTET GYNECOL JI Am. J. Obstet. Gynecol. PD OCT PY 1990 VL 163 IS 4 BP 1168 EP 1171 PN 1 PG 4 WC Obstetrics & Gynecology SC Obstetrics & Gynecology GA EE716 UT WOS:A1990EE71600016 PM 2171338 ER PT J AU PORTER, JDH GAFFNEY, C HEYMANN, D PARKIN, W AF PORTER, JDH GAFFNEY, C HEYMANN, D PARKIN, W TI FOOD-BORNE OUTBREAK OF GIARDIA-LAMBLIA SO AMERICAN JOURNAL OF PUBLIC HEALTH LA English DT Note C1 NEW JERSEY DEPT HLTH,DIV EPIDEMIOL & DIS CONTROL,TRENTON,NJ. RP PORTER, JDH (reprint author), CTR DIS CONTROL,DIV FIELD SERV,EPIDEMIOL PROGRAM OFF,ATLANTA,GA 30333, USA. NR 8 TC 34 Z9 36 U1 0 U2 1 PU AMER PUBLIC HEALTH ASSN INC PI WASHINGTON PA 1015 FIFTEENTH ST NW, WASHINGTON, DC 20005 SN 0090-0036 J9 AM J PUBLIC HEALTH JI Am. J. Public Health PD OCT PY 1990 VL 80 IS 10 BP 1259 EP 1260 DI 10.2105/AJPH.80.10.1259 PG 2 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EA291 UT WOS:A1990EA29100021 PM 2400040 ER PT J AU STEENLAND, NK THUN, MJ AF STEENLAND, NK THUN, MJ TI LEAD RISKS OVERLOOKED IN SANDBLASTERS - RESPONSE SO AMERICAN JOURNAL OF PUBLIC HEALTH LA English DT Letter RP STEENLAND, NK (reprint author), NIOSH,ROBERT A TAFT LABS,R13,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 4 TC 1 Z9 1 U1 0 U2 0 PU AMER PUBLIC HEALTH ASSN INC PI WASHINGTON PA 1015 FIFTEENTH ST NW, WASHINGTON, DC 20005 SN 0090-0036 J9 AM J PUBLIC HEALTH JI Am. J. Public Health PD OCT PY 1990 VL 80 IS 10 BP 1275 EP 1276 DI 10.2105/AJPH.80.10.1275-a PG 2 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA EA291 UT WOS:A1990EA29100033 ER PT J AU RUEBUSH, TK CAMPBELL, GH MORENO, A PATARROYO, ME COLLINS, WE AF RUEBUSH, TK CAMPBELL, GH MORENO, A PATARROYO, ME COLLINS, WE TI IMMUNIZATION OF OWL MONKEYS WITH A COMBINATION OF PLASMODIUM-FALCIPARUM ASEXUAL BLOOD-STAGE SYNTHETIC PEPTIDE ANTIGENS SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article C1 UNIV NACL COLOMBIA, HOSP SAN JUAN DIOS, INST INMUNOL, SANTA FE DE BOGOTA, COLOMBIA. RP RUEBUSH, TK (reprint author), CTR DIS CONTROL, CTR INFECT DIS, MALARIA BRANCH, F12, ATLANTA, GA 30333 USA. NR 9 TC 43 Z9 43 U1 0 U2 0 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DR, STE 130, MCLEAN, VA 22101 USA SN 0002-9637 EI 1476-1645 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD OCT PY 1990 VL 43 IS 4 BP 355 EP 366 PG 12 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA EG432 UT WOS:A1990EG43200005 PM 2240363 ER PT J AU REEVES, WC CUTLER, JR GRACIA, F KAPLAN, JE CASTILLO, L HARTLEY, TM BRENES, MM LARREATEGUI, M DELAO, SL ARCHBOLD, C LAIRMORE, MD LEVINE, PH AF REEVES, WC CUTLER, JR GRACIA, F KAPLAN, JE CASTILLO, L HARTLEY, TM BRENES, MM LARREATEGUI, M DELAO, SL ARCHBOLD, C LAIRMORE, MD LEVINE, PH TI HUMAN T-CELL LYMPHOTROPIC VIRUS-INFECTION IN GUAYMI INDIANS FROM PANAMA SO AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE LA English DT Article C1 CTR DIS CONTROL,EPIDEMIOL PROGRAM OFF,DIV FIELD SERV,ATLANTA,GA 30333. GORGAS MEM LAB,DIV EPIDEMIOL,PANAMA CITY,PANAMA. NCI,BETHESDA,MD 20892. RP REEVES, WC (reprint author), CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,VIRAL EXANTHERMS & HERPESVIRUS BRANCH,ATLANTA,GA 30333, USA. FU NCI NIH HHS [NCI-CP-31015] NR 29 TC 35 Z9 36 U1 0 U2 0 PU AMER SOC TROP MED & HYGIENE PI MCLEAN PA 8000 WESTPARK DRIVE SUITE 130, MCLEAN, VA 22101 SN 0002-9637 J9 AM J TROP MED HYG JI Am. J. Trop. Med. Hyg. PD OCT PY 1990 VL 43 IS 4 BP 410 EP 418 PG 9 WC Public, Environmental & Occupational Health; Tropical Medicine SC Public, Environmental & Occupational Health; Tropical Medicine GA EG432 UT WOS:A1990EG43200013 PM 2240369 ER PT J AU SAUTER, SL MURPHY, LR HURRELL, JJ AF SAUTER, SL MURPHY, LR HURRELL, JJ TI PREVENTION OF WORK-RELATED PSYCHOLOGICAL DISORDERS - A NATIONAL STRATEGY PROPOSED BY THE NATIONAL-INSTITUTE-FOR-OCCUPATIONAL-SAFETY-AND-HEALTH (NIOSH) SO AMERICAN PSYCHOLOGIST LA English DT Article RP SAUTER, SL (reprint author), NIOSH,DIV BIOMED & BEHAV SCI,4676 COLUMBIA PKWY,CINCINNATI,OH 45226, USA. NR 97 TC 133 Z9 137 U1 1 U2 12 PU AMER PSYCHOLOGICAL ASSOC PI WASHINGTON PA 750 FIRST ST NE, WASHINGTON, DC 20002-4242 SN 0003-066X J9 AM PSYCHOL JI Am. Psychol. PD OCT PY 1990 VL 45 IS 10 BP 1146 EP 1158 DI 10.1037/0003-066X.45.10.1146 PG 13 WC Psychology, Multidisciplinary SC Psychology GA EC507 UT WOS:A1990EC50700006 PM 2252233 ER PT J AU MILLAR, JD AF MILLAR, JD TI MENTAL-HEALTH AND THE WORKPLACE - AN INTERCHANGEABLE PARTNERSHIP SO AMERICAN PSYCHOLOGIST LA English DT Article RP MILLAR, JD (reprint author), CTR DIS CONTROL,NIOSH,ROOM 3007,BLDG 1,MS D-36,1600 CLIFTON RD,ATLANTA,GA 30333, USA. NR 6 TC 6 Z9 7 U1 0 U2 1 PU AMER PSYCHOLOGICAL ASSOC PI WASHINGTON PA 750 FIRST ST NE, WASHINGTON, DC 20002-4242 SN 0003-066X J9 AM PSYCHOL JI Am. Psychol. PD OCT PY 1990 VL 45 IS 10 BP 1165 EP 1166 DI 10.1037/0003-066X.45.10.1165 PG 2 WC Psychology, Multidisciplinary SC Psychology GA EC507 UT WOS:A1990EC50700009 PM 2252236 ER PT J AU COX, DL RILEY, B CHANG, P SAYAHTAHERI, S TASSELL, S HEVELONE, J AF COX, DL RILEY, B CHANG, P SAYAHTAHERI, S TASSELL, S HEVELONE, J TI EFFECTS OF MOLECULAR-OXYGEN, OXIDATION-REDUCTION POTENTIAL, AND ANTIOXIDANTS UPON INVITRO REPLICATION OF TREPONEMA-PALLIDUM SUBSP PALLIDUM SO APPLIED AND ENVIRONMENTAL MICROBIOLOGY LA English DT Article C1 UNIV TEXAS,HLTH SCI CTR,DEPT MICROBIOL & IMMUNOL,DALLAS,TX 75235. BAYLOR RES FDN,DEPT CELL BIOL,DALLAS,TX 75266. MED COLL VIRGINIA HOSP,DEPT PATHOL,RICHMOND,VA 23298. TEXAS COLL OSTEOPATH MED,DEPT MICROBIOL & IMMUNOL,FT WORTH,TX 76107. RP COX, DL (reprint author), CTR DIS CONTROL,DIV SEXUALLY TRANSMITTED DIS LAB RES,TREPONEMA RES PROGRAM,ATLANTA,GA 30333, USA. FU NIAID NIH HHS [AI-23595, AI-15113] NR 49 TC 31 Z9 32 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0099-2240 J9 APPL ENVIRON MICROB JI Appl. Environ. Microbiol. PD OCT PY 1990 VL 56 IS 10 BP 3063 EP 3072 PG 10 WC Biotechnology & Applied Microbiology; Microbiology SC Biotechnology & Applied Microbiology; Microbiology GA EB611 UT WOS:A1990EB61100019 PM 2285317 ER PT J AU WHITE, LA FREEMAN, CY HALL, HE FORRESTER, BD AF WHITE, LA FREEMAN, CY HALL, HE FORRESTER, BD TI INACTIVATION AND STABILITY OF VIRAL DIAGNOSTIC REAGENTS TREATED BY GAMMA-RADIATION SO BIOLOGICALS LA English DT Article C1 CTR DIS CONTROL,CTR DIS CONTROL,DIV VIRAL DIS,ATLANTA,GA 30333. CTR DIS CONTROL,CTR DIS CONTROL,SCI RESOURCES PROGRAM,ATLANTA,GA 30333. NR 17 TC 8 Z9 8 U1 0 U2 0 PU ACADEMIC PRESS LTD PI LONDON PA 24-28 OVAL RD, LONDON, ENGLAND NW1 7DX SN 1045-1056 J9 BIOLOGICALS JI Biologicals PD OCT PY 1990 VL 18 IS 4 BP 271 EP 280 DI 10.1016/1045-1056(90)90029-Y PG 10 WC Biochemical Research Methods; Biotechnology & Applied Microbiology; Pharmacology & Pharmacy SC Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology; Pharmacology & Pharmacy GA EK853 UT WOS:A1990EK85300003 PM 2126734 ER PT J AU JOHNSON, D FISHER, R HELWICK, J PATTERSON, M HOLWERDA, J MURRAY, D AF JOHNSON, D FISHER, R HELWICK, J PATTERSON, M HOLWERDA, J MURRAY, D TI USE OF A VERY HIGH MATERNAL SERUM ALPHA-FETOPROTEIN LEVEL AS A MARKER FOR RECENT HUMAN PARVOVIRUS INFECTION SO CLINICAL RESEARCH LA English DT Meeting Abstract C1 CTR DIS CONTROL,ATLANTA,GA 30333. MICHIGAN STATE UNIV,E LANSING,MI 48824. MICHIGAN DEPT PUBL HLTH,LANSING,MI. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 SN 0009-9279 J9 CLIN RES JI Clin. Res. PD OCT PY 1990 VL 38 IS 3 BP A899 EP A899 PG 1 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA EA235 UT WOS:A1990EA23500725 ER PT J AU SHA, B HARRIS, AA BENSON, CA URBANSKI, P STEWART, JA ATKINSON, W WILLIAMS, WW MURPHY, RL LEVIN, S KESSLER, HA AF SHA, B HARRIS, AA BENSON, CA URBANSKI, P STEWART, JA ATKINSON, W WILLIAMS, WW MURPHY, RL LEVIN, S KESSLER, HA TI PREVALENCE OF MEASLES ANTIBODIES IN ASYMPTOMATIC HIV+ ADULTS SO CLINICAL RESEARCH LA English DT Meeting Abstract C1 RUSH PRESBYTERIAN ST LUKES MED CTR,CHICAGO,IL 60612. NW MEM HOSP,CHICAGO,IL 60611. CTR DIS CONTROL,ATLANTA,GA 30333. NR 0 TC 0 Z9 0 U1 0 U2 0 PU SLACK INC PI THOROFARE PA 6900 GROVE RD, THOROFARE, NJ 08086 SN 0009-9279 J9 CLIN RES JI Clin. Res. PD OCT PY 1990 VL 38 IS 3 BP A845 EP A845 PG 1 WC Medicine, Research & Experimental SC Research & Experimental Medicine GA EA235 UT WOS:A1990EA23500439 ER PT J AU SOSENKO, JM KATO, M SOTO, R BILD, DE AF SOSENKO, JM KATO, M SOTO, R BILD, DE TI COMPARISON OF QUANTITATIVE SENSORY-THRESHOLD MEASURES FOR THEIR ASSOCIATION WITH FOOT ULCERATION IN DIABETIC-PATIENTS SO DIABETES CARE LA English DT Article C1 CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV DIABET TRANSLAT,ATLANTA,GA 30333. RP SOSENKO, JM (reprint author), UNIV MIAMI,SCH MED,DEPT MED,R-103,POB 016960,MIAMI,FL 33101, USA. FU PHS HHS [200-88-0648 (P)] NR 20 TC 109 Z9 111 U1 0 U2 0 PU AMER DIABETES ASSOC PI ALEXANDRIA PA 1660 DUKE ST, ALEXANDRIA, VA 22314 SN 0149-5992 J9 DIABETES CARE JI Diabetes Care PD OCT PY 1990 VL 13 IS 10 BP 1057 EP 1061 DI 10.2337/diacare.13.10.1057 PG 5 WC Endocrinology & Metabolism SC Endocrinology & Metabolism GA EA914 UT WOS:A1990EA91400006 PM 2209302 ER PT J AU BRADLEY, DW KRAWCZYNSKI, K EBERT, JW MCCAUSTLAND, KA CHOO, QL HOUGHTON, MA KUO, G AF BRADLEY, DW KRAWCZYNSKI, K EBERT, JW MCCAUSTLAND, KA CHOO, QL HOUGHTON, MA KUO, G TI PARENTERALLY TRANSMITTED NON-A, NON-B HEPATITIS - VIRUS-SPECIFIC ANTIBODY-RESPONSE PATTERNS IN HEPATITIS-C VIRUS-INFECTED CHIMPANZEES SO GASTROENTEROLOGY LA English DT Article C1 CHIRON CORP,EMERYVILLE,CA. RP BRADLEY, DW (reprint author), CTR DIS CONTROL,HEPATITIS BRANCH,B6 ROOM 192,1600 CLIFTON RD NE,ATLANTA,GA 30333, USA. NR 19 TC 51 Z9 51 U1 0 U2 1 PU W B SAUNDERS CO PI PHILADELPHIA PA INDEPENDENCE SQUARE WEST CURTIS CENTER, STE 300, PHILADELPHIA, PA 19106-3399 SN 0016-5085 J9 GASTROENTEROLOGY JI Gastroenterology PD OCT PY 1990 VL 99 IS 4 BP 1054 EP 1060 PG 7 WC Gastroenterology & Hepatology SC Gastroenterology & Hepatology GA DY353 UT WOS:A1990DY35300022 PM 1697546 ER PT J AU HAO, MV BRENNER, DJ STEIGERWALT, AG KOSAKO, Y KOMAGATA, K AF HAO, MV BRENNER, DJ STEIGERWALT, AG KOSAKO, Y KOMAGATA, K TI ERWINIA-PERSICINUS, A NEW SPECIES ISOLATED FROM PLANTS SO INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY LA English DT Article C1 CTR DIS CONTROL,DIV BACTERIAL DIS,MENINGITIS & SPECIAL PATHOGENS BRANCH,ATLANTA,GA 30333. UNIV TOKYO,INST APPL MICROBIOL,BUNKYO KU,TOKYO 113,JAPAN. JAPAN COLLECT MICROORGANISMS,WAKO,SAITAMA 35101,JAPAN. NR 13 TC 31 Z9 33 U1 0 U2 5 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0020-7713 J9 INT J SYST BACTERIOL JI Int. J. Syst. Bacteriol. PD OCT PY 1990 VL 40 IS 4 BP 379 EP 383 PG 5 WC Microbiology SC Microbiology GA ED272 UT WOS:A1990ED27200006 PM 2275853 ER PT J AU STROUP, NE FRENITITULAER, LWJ SCHWARTZ, JJ AF STROUP, NE FRENITITULAER, LWJ SCHWARTZ, JJ TI UNEXPECTED GEOGRAPHIC-VARIATION IN RATES OF HOSPITALIZATION FOR PATIENTS WHO HAVE FRACTURE OF THE HIP - MEDICARE ENROLLEES IN THE UNITED-STATES SO JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME LA English DT Article C1 ARKANSAS DEPT HLTH,LITTLE ROCK,AR 72205. EMORY UNIV,SCH MED,ATLANTA,GA 30322. RP STROUP, NE (reprint author), CTR DIS CONTROL,CTR DIS PREVENT & HLTH PROMOT,EPIDEMIOL PROGRAM OFF,ATLANTA,GA 30333, USA. NR 22 TC 31 Z9 31 U1 2 U2 2 PU JOURNAL BONE JOINT SURGERY INC PI NEEDHAM PA 20 PICKERING ST, NEEDHAM, MA 02192 SN 0021-9355 J9 J BONE JOINT SURG AM JI J. Bone Joint Surg.-Am. Vol. PD OCT PY 1990 VL 72A IS 9 BP 1294 EP 1298 PG 5 WC Orthopedics; Surgery SC Orthopedics; Surgery GA EE781 UT WOS:A1990EE78100003 PM 2229103 ER PT J AU HIGH, WM LEVIN, HS GARY, HE AF HIGH, WM LEVIN, HS GARY, HE TI RECOVERY OF ORIENTATION FOLLOWING CLOSED-HEAD INJURY SO JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY LA English DT Article C1 UNIV TEXAS,MED BRANCH,DIV NEUROSURG D73,GALVESTON,TX 77550. DEL ORO INST REHABIL,DEPT NEUROPSYCHOL,HOUSTON,TX. CTR DIS CONTROL,ATLANTA,GA 30333. FU NINDS NIH HHS [NS-21889] NR 17 TC 44 Z9 44 U1 0 U2 0 PU SWETS ZEITLINGER PUBLISHERS PI LISSE PA P O BOX 825, 2160 SZ LISSE, NETHERLANDS SN 1380-3395 J9 J CLIN EXP NEUROPSYC JI J. Clin. Exp. Neuropsychol. PD OCT PY 1990 VL 12 IS 5 BP 703 EP 714 DI 10.1080/01688639008401013 PG 12 WC Psychology, Clinical; Clinical Neurology; Psychology SC Psychology; Neurosciences & Neurology GA EE600 UT WOS:A1990EE60000007 PM 2258432 ER PT J AU RUSSELL, H THARPE, JA WELLS, DE WHITE, EH JOHNSON, JE AF RUSSELL, H THARPE, JA WELLS, DE WHITE, EH JOHNSON, JE TI MONOCLONAL-ANTIBODY RECOGNIZING A SPECIES-SPECIFIC PROTEIN FROM STREPTOCOCCUS-PNEUMONIAE SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,DIV IMMUNOL ONCOL & HEMATOL DIS,ULTRASTRUCT PATHOL LAB,ATLANTA,GA 30333. RP RUSSELL, H (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV MOLEC SCI,ATLANTA,GA 30333, USA. NR 45 TC 60 Z9 62 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD OCT PY 1990 VL 28 IS 10 BP 2191 EP 2195 PG 5 WC Microbiology SC Microbiology GA DZ425 UT WOS:A1990DZ42500008 PM 2229341 ER PT J AU GARGEYA, IB PRUITT, WR SIMMONS, RB MEYER, SA AHEARN, DG AF GARGEYA, IB PRUITT, WR SIMMONS, RB MEYER, SA AHEARN, DG TI OCCURRENCE OF CLAVISPORA-LUSITANIAE, THE TELEOMORPH OF CANDIDA-LUSITANIAE, AMONG CLINICAL ISOLATES SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article C1 GEORGIA STATE UNIV,MICROBIAL & BIOCHEM SCI LAB,ATLANTA,GA 30303. CTR DIS CONTROL,CTR INFECT DIS,DIV MYCOT DIS,ATLANTA,GA 30333. NR 20 TC 15 Z9 15 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD OCT PY 1990 VL 28 IS 10 BP 2224 EP 2227 PG 4 WC Microbiology SC Microbiology GA DZ425 UT WOS:A1990DZ42500015 PM 2229346 ER PT J AU KIM, KH YANG, JM JOO, SI CHO, YG GLASS, RI CHO, YJ AF KIM, KH YANG, JM JOO, SI CHO, YG GLASS, RI CHO, YJ TI IMPORTANCE OF ROTAVIRUS AND ADENOVIRUS TYPE-40 AND TYPE-41 IN ACUTE GASTROENTERITIS IN KOREAN CHILDREN SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article C1 SUNGKUNKWAN UNIV,COLL MED,DEPT GENET ENGN,SUWON,SOUTH KOREA. CTR DIS CONTROL,CTR INFECT DIS,VIRAL GASTROENTERITIS UNIT,ATLANTA,GA 30333. RP KIM, KH (reprint author), HANYANG UNIV,COLL MED,DEPT MICROBIOL,SEOUL 133791,SOUTH KOREA. NR 43 TC 51 Z9 51 U1 0 U2 1 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD OCT PY 1990 VL 28 IS 10 BP 2279 EP 2284 PG 6 WC Microbiology SC Microbiology GA DZ425 UT WOS:A1990DZ42500025 PM 2172286 ER PT J AU POPOVICUROIC, T PATTON, CM NICHOLSON, MA KIEHLBAUCH, JA AF POPOVICUROIC, T PATTON, CM NICHOLSON, MA KIEHLBAUCH, JA TI EVALUATION OF THE INDOXYL ACETATE HYDROLYSIS TEST FOR RAPID DIFFERENTIATION OF CAMPYLOBACTER, HELICOBACTER, AND WOLINELLA SPECIES SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Article RP POPOVICUROIC, T (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV MOLEC SCI,ATLANTA,GA 30333, USA. NR 39 TC 37 Z9 38 U1 0 U2 2 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD OCT PY 1990 VL 28 IS 10 BP 2335 EP 2339 PG 5 WC Microbiology SC Microbiology GA DZ425 UT WOS:A1990DZ42500035 PM 2229360 ER PT J AU LEWIS, JS KRANIGBROWN, D TRAINOR, DA AF LEWIS, JS KRANIGBROWN, D TRAINOR, DA TI DNA PROBE CONFIRMATORY TEST FOR NEISSERIA-GONORRHOEAE SO JOURNAL OF CLINICAL MICROBIOLOGY LA English DT Note C1 GEN PROBE INC,SAN DIEGO,CA 92121. RP LEWIS, JS (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV SEXUALLY TRANSMITTED DIS LAB,ATLANTA,GA 30333, USA. NR 7 TC 17 Z9 18 U1 0 U2 0 PU AMER SOC MICROBIOLOGY PI WASHINGTON PA 1325 MASSACHUSETTS AVENUE, NW, WASHINGTON, DC 20005-4171 SN 0095-1137 J9 J CLIN MICROBIOL JI J. Clin. Microbiol. PD OCT PY 1990 VL 28 IS 10 BP 2349 EP 2350 PG 2 WC Microbiology SC Microbiology GA DZ425 UT WOS:A1990DZ42500038 PM 2121785 ER PT J AU HEALEY, D DIANDA, L MOORE, JP MCDOUGAL, JS MOORE, MJ ESTESS, P BUCK, D KWONG, PD BEVERLEY, PCL SATTENTAU, QJ AF HEALEY, D DIANDA, L MOORE, JP MCDOUGAL, JS MOORE, MJ ESTESS, P BUCK, D KWONG, PD BEVERLEY, PCL SATTENTAU, QJ TI NOVEL ANTI-CD4 MONOCLONAL-ANTIBODIES SEPARATE HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION AND FUSION OF CD4+ CELLS FROM VIRUS BINDING SO JOURNAL OF EXPERIMENTAL MEDICINE LA English DT Article C1 COLUMBIA UNIV COLL PHYS & SURG,HOWARD HUGHES MED INST,6TH FLOOR PI ANNEX,722 W 168TH ST,NEW YORK,NY 10032. UNIV COLL & MIDDLESEX SCH MED,ACAD DEPT GENITOURINARY MED,LONDON W1,ENGLAND. IMPERIAL CANC RES FUND,HUMAN TUMOR IMMUNOL GRP,LONDON W1,ENGLAND. BECTON DICKINSON MONOCLONAL CTR INC,SAN JOSE,CA 95131. CTR DIS CONTROL,IMMUNOL BRANCH,ATLANTA,GA 30333. NR 37 TC 213 Z9 213 U1 0 U2 1 PU ROCKEFELLER UNIV PRESS PI NEW YORK PA 222 E 70TH STREET, NEW YORK, NY 10021 SN 0022-1007 J9 J EXP MED JI J. Exp. Med. PD OCT 1 PY 1990 VL 172 IS 4 BP 1233 EP 1242 DI 10.1084/jem.172.4.1233 PG 10 WC Immunology; Medicine, Research & Experimental SC Immunology; Research & Experimental Medicine GA EA454 UT WOS:A1990EA45400027 PM 1698911 ER PT J AU HAAS, JS BOLAN, G LARSEN, SA CLEMENT, MJ BACCHETTI, P MOSS, AR AF HAAS, JS BOLAN, G LARSEN, SA CLEMENT, MJ BACCHETTI, P MOSS, AR TI SENSITIVITY OF TREPONEMAL TESTS FOR DETECTING PRIOR TREATED SYPHILIS DURING HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION SO JOURNAL OF INFECTIOUS DISEASES LA English DT Article C1 SAN FRANCISCO GEN HOSP,DIV GEN INTERNAL MED,SAN FRANCISCO,CA 94110. SAN FRANCISCO GEN HOSP,DIV AIDS ONCOL,SAN FRANCISCO,CA 94110. UNIV CALIF SAN FRANCISCO,DEPT MED,SAN FRANCISCO,CA 94143. UNIV CALIF SAN FRANCISCO,DEPT EPIDEMIOL & INT HLTH,SAN FRANCISCO,CA 94143. DEPT PUBL HLTH,SAN FRANCISCO,CA. CTR DIS CONTROL,ATLANTA,GA 30333. NR 24 TC 90 Z9 92 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD OCT PY 1990 VL 162 IS 4 BP 862 EP 866 PG 5 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EA376 UT WOS:A1990EA37600012 PM 1976130 ER PT J AU KREISS, JK CASTRO, KG AF KREISS, JK CASTRO, KG TI SPECIAL CONSIDERATIONS FOR MANAGING SUSPECTED HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION AND AIDS IN PATIENTS FROM DEVELOPING-COUNTRIES SO JOURNAL OF INFECTIOUS DISEASES LA English DT Editorial Material C1 UNIV WASHINGTON,DEPT EPIDEMIOL,SEATTLE,WA 98195. UNIV WASHINGTON,DEPT MED,SEATTLE,WA 98195. CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,ATLANTA,GA 30333. FU NIAID NIH HHS [AI-25024] NR 33 TC 23 Z9 23 U1 0 U2 0 PU UNIV CHICAGO PRESS PI CHICAGO PA 5720 S WOODLAWN AVE, CHICAGO, IL 60637 SN 0022-1899 J9 J INFECT DIS JI J. Infect. Dis. PD OCT PY 1990 VL 162 IS 4 BP 955 EP 960 PG 6 WC Immunology; Infectious Diseases; Microbiology SC Immunology; Infectious Diseases; Microbiology GA EA376 UT WOS:A1990EA37600026 PM 2205654 ER PT J AU PEDERSEN, DH VENABLE, HL SIEBER, WK AF PEDERSEN, DH VENABLE, HL SIEBER, WK TI AN EXAMINATION OF OCCUPATIONAL-MEDICINE PRACTICES SO JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE LA English DT Article RP PEDERSEN, DH (reprint author), NIOSH,CTR DIS CONTROL,DIV SURVEILLANCE HAZARD EVALUAT & FIELD STUDIES,CINCINNATI,OH 45226, USA. NR 35 TC 6 Z9 6 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 1076-2752 J9 J OCCUP ENVIRON MED JI J. Occup. Environ. Med. PD OCT PY 1990 VL 32 IS 10 BP 1037 EP 1041 PG 5 WC Public, Environmental & Occupational Health SC Public, Environmental & Occupational Health GA ED508 UT WOS:A1990ED50800015 PM 2262824 ER PT J AU COLLINS, WE RUEBUSH, TK SKINNER, JC FILIPSKI, VK BRODERSON, JR STANFILL, PS MORRIS, CL AF COLLINS, WE RUEBUSH, TK SKINNER, JC FILIPSKI, VK BRODERSON, JR STANFILL, PS MORRIS, CL TI THE PERUVIAN-III STRAIN OF PLASMODIUM-BRASILIANUM IN SAIMIRI-SCIUREUS-BOLIVIENSIS MONKEYS SO JOURNAL OF PARASITOLOGY LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,OFF SCI SERV,ATLANTA,GA 30333. RP COLLINS, WE (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV OSTEOPATH MED,MALARIA BRANCH,ATLANTA,GA 30333, USA. NR 6 TC 9 Z9 9 U1 0 U2 0 PU AMER SOC PARASITOLOGISTS PI LAWRENCE PA 810 EAST 10TH STREET, LAWRENCE, KS 66044 SN 0022-3395 J9 J PARASITOL JI J. Parasitol. PD OCT PY 1990 VL 76 IS 5 BP 676 EP 680 DI 10.2307/3282981 PG 5 WC Parasitology SC Parasitology GA EB627 UT WOS:A1990EB62700012 PM 2213410 ER PT J AU COLLINS, WE SKINNER, JC FILIPSKI, VK BRODERSON, JR STANFILL, PS MORRIS, CL AF COLLINS, WE SKINNER, JC FILIPSKI, VK BRODERSON, JR STANFILL, PS MORRIS, CL TI TRANSMISSION OF PLASMODIUM-FRAGILE TO SAIMIRI MONKEYS SO JOURNAL OF PARASITOLOGY LA English DT Note C1 CTR DIS CONTROL,CTR INFECT DIS,SCI RESOURCES PROGRAM,ATLANTA,GA 30333. RP COLLINS, WE (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,MALARIA BRANCH,ATLANTA,GA 30333, USA. NR 10 TC 10 Z9 10 U1 0 U2 0 PU AMER SOC PARASITOLOGISTS PI LAWRENCE PA 810 EAST 10TH STREET, LAWRENCE, KS 66044 SN 0022-3395 J9 J PARASITOL JI J. Parasitol. PD OCT PY 1990 VL 76 IS 5 BP 730 EP 732 DI 10.2307/3282990 PG 3 WC Parasitology SC Parasitology GA EB627 UT WOS:A1990EB62700021 PM 2213417 ER PT J AU SMITH, JS YAGER, PA BIGLER, WJ HARTWIG, EC AF SMITH, JS YAGER, PA BIGLER, WJ HARTWIG, EC TI SURVEILLANCE AND EPIDEMIOLOGIC MAPPING OF MONOCLONAL ANTIBODY-DEFINED RABIES VARIANTS IN FLORIDA SO JOURNAL OF WILDLIFE DISEASES LA English DT Article C1 FLORIDA DEPT HLTH & REHAB SERV,STATE HLTH OFF,TALLAHASSEE,FL 32399. FLORIDA DEPT HLTH & REHAB SERV,OFF LAB SERV,JACKSONVILLE,FL 32210. RP SMITH, JS (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,VIRAL & RICKETTSIAL ZOONOSES BRANCH,ATLANTA,GA 30333, USA. NR 22 TC 21 Z9 21 U1 0 U2 0 PU WILDLIFE DISEASE ASSN, INC PI LAWRENCE PA 810 EAST 10TH ST, LAWRENCE, KS 66044-8897 SN 0090-3558 J9 J WILDLIFE DIS JI J. Wildl. Dis. PD OCT PY 1990 VL 26 IS 4 BP 473 EP 485 PG 13 WC Veterinary Sciences SC Veterinary Sciences GA EF705 UT WOS:A1990EF70500008 PM 2250324 ER PT J AU PASKEWITZ, SM COLLINS, FH AF PASKEWITZ, SM COLLINS, FH TI USE OF THE POLYMERASE CHAIN-REACTION TO IDENTIFY MOSQUITO SPECIES OF THE ANOPHELES-GAMBIAE COMPLEX SO MEDICAL AND VETERINARY ENTOMOLOGY LA English DT Article RP PASKEWITZ, SM (reprint author), CTR DIS CONTROL,CTR INFECTIOUS DIS,DIV PARASIT DIS,MALARIA BRANCH,MAILSTOP F-12,ATLANTA,GA 30333, USA. NR 0 TC 120 Z9 123 U1 2 U2 5 PU BLACKWELL SCIENCE LTD PI OXFORD PA OSNEY MEAD, OXFORD, OXON, ENGLAND OX2 0EL SN 0269-283X J9 MED VET ENTOMOL JI Med. Vet. Entomol. PD OCT PY 1990 VL 4 IS 4 BP 367 EP 373 DI 10.1111/j.1365-2915.1990.tb00453.x PG 7 WC Entomology; Veterinary Sciences SC Entomology; Veterinary Sciences GA EG824 UT WOS:A1990EG82400002 PM 2133004 ER PT J AU TOROK, TJ AF TOROK, TJ TI HUMAN PARVOVIRUS B19 INFECTIONS IN PREGNANCY SO PEDIATRIC INFECTIOUS DISEASE JOURNAL LA English DT Article; Proceedings Paper CT SYMP ON PERINATAL INFECTIOUS DISEASES : UPDATE 1990 CY 1990 CL EVANSTON, IL SP EVANSTON HOSP, DEPT PEDIAT, OBSTET & GYNECOL, EVANSTON HOSP, GERTRUDE VICTORSON LECTURE FUND RP TOROK, TJ (reprint author), US PHS,CTR DIS CONTROL,CTR INFECT DIS,DIV VIRAL & RICKETTSIAL DIS,RESP & ENTEROVIRUS BRANCH,ATLANTA,GA 30306, USA. NR 39 TC 24 Z9 24 U1 0 U2 0 PU WILLIAMS & WILKINS PI BALTIMORE PA 351 WEST CAMDEN ST, BALTIMORE, MD 21201-2436 SN 0891-3668 J9 PEDIATR INFECT DIS J JI Pediatr. Infect. Dis. J. PD OCT PY 1990 VL 9 IS 10 BP 772 EP 776 PG 5 WC Immunology; Infectious Diseases; Pediatrics SC Immunology; Infectious Diseases; Pediatrics GA EC315 UT WOS:A1990EC31500028 PM 2172907 ER PT J AU MOYER, LA ALTER, MJ FAVERO, MS AF MOYER, LA ALTER, MJ FAVERO, MS TI HEMODIALYSIS-ASSOCIATED HEPATITIS-B - REVISED RECOMMENDATIONS FOR SEROLOGIC SCREENING SO SEMINARS IN DIALYSIS LA English DT Editorial Material RP MOYER, LA (reprint author), CTR DIS CONTROL,CTR INFECT DIS,HEPATITIS BRANCH,DIV VIRAL & RICKETTSIAL DIS,BLDG 6,ROOM 154,ATLANTA,GA 30333, USA. NR 0 TC 19 Z9 20 U1 0 U2 0 PU BLACKWELL SCIENCE INC PI CAMBRIDGE PA 238 MAIN ST, CAMBRIDGE, MA 02142 SN 0894-0959 J9 SEMIN DIALYSIS JI Semin. Dial. PD OCT-DEC PY 1990 VL 3 IS 4 BP 201 EP 204 DI 10.1111/j.1525-139X.1990.tb00045.x PG 4 WC Urology & Nephrology SC Urology & Nephrology GA EG777 UT WOS:A1990EG77700002 ER PT J AU FARLEY, TA HADLER, JL GUNN, RA AF FARLEY, TA HADLER, JL GUNN, RA TI THE SYPHILIS EPIDEMIC IN CONNECTICUT - RELATIONSHIP TO DRUG-USE AND PROSTITUTION SO SEXUALLY TRANSMITTED DISEASES LA English DT Article C1 CONNECTICUT DEPT HLTH SERV,DIV PREVENTABLE DIS,HARTFORD,CT. CTR DIS CONTROL,DIV FIELD SERV,EPIDEMIOL PROGRAM OFF,ATLANTA,GA 30333. NR 22 TC 54 Z9 54 U1 1 U2 1 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0148-5717 J9 SEX TRANSM DIS JI Sex. Transm. Dis. PD OCT-DEC PY 1990 VL 17 IS 4 BP 163 EP 168 PG 6 WC Infectious Diseases SC Infectious Diseases GA EJ738 UT WOS:A1990EJ73800003 PM 2264004 ER PT J AU ARAL, SO WASSERHEIT, JN GREEN, SB JUDSON, FN SPARLING, PF AF ARAL, SO WASSERHEIT, JN GREEN, SB JUDSON, FN SPARLING, PF TI REPORT OF THE NIAID STUDY-GROUP-ON-INTEGRATED-BEHAVIORAL-RESEARCH-FOR-PREVENTION-AND-CONTROL -OF-SEXUALLY-TRANSMITTED-DISEASES .3. ISSUES IN EVALUATING BEHAVIORAL INTERVENTIONS SO SEXUALLY TRANSMITTED DISEASES LA English DT Article C1 UNIV N CAROLINA,DEPT MED,CHAPEL HILL,NC 27514. NIH,SEXUALLY TRANSMITTED DIS BRANCH,BETHESDA,MD 20892. NCI,CLIN & DIAGNOST TRIALS SECT,BETHESDA,MD 20892. WHO,SEXUALLY TRANSMITTED DIS PROGRAMME,CH-1211 GENEVA 27,SWITZERLAND. RP ARAL, SO (reprint author), CTR DIS CONTROL,BEHAV STUDIES SECT,ATLANTA,GA 30333, USA. NR 8 TC 3 Z9 3 U1 0 U2 0 PU LIPPINCOTT-RAVEN PUBL PI PHILADELPHIA PA 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 SN 0148-5717 J9 SEX TRANSM DIS JI Sex. Transm. Dis. PD OCT-DEC PY 1990 VL 17 IS 4 BP 208 EP 210 PG 3 WC Infectious Diseases SC Infectious Diseases GA EJ738 UT WOS:A1990EJ73800012 PM 2264011 ER PT J AU STROUP, NE EDMONDS, L OBRIEN, TR AF STROUP, NE EDMONDS, L OBRIEN, TR TI RENAL AGENESIS AND DYSGENESIS - ARE THEY INCREASING SO TERATOLOGY LA English DT Article C1 CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,ATLANTA,GA 30333. CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,ATLANTA,GA 30333. NR 21 TC 12 Z9 13 U1 0 U2 0 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0040-3709 J9 TERATOLOGY JI Teratology PD OCT PY 1990 VL 42 IS 4 BP 383 EP 395 DI 10.1002/tera.1420420407 PG 13 WC Developmental Biology; Toxicology SC Developmental Biology; Toxicology GA EE173 UT WOS:A1990EE17300006 PM 2256002 ER PT J AU CLEMENS, JD SACK, DA CHAKRABORTY, J RAO, MR AHMED, F HARRIS, JR VANLOON, F KHAN, MR YUNIS, M HUDA, S KAY, BA SVENNERHOLM, AM HOLMGREN, J AF CLEMENS, JD SACK, DA CHAKRABORTY, J RAO, MR AHMED, F HARRIS, JR VANLOON, F KHAN, MR YUNIS, M HUDA, S KAY, BA SVENNERHOLM, AM HOLMGREN, J TI FIELD TRIAL OF ORAL CHOLERA VACCINES IN BANGLADESH - EVALUATION OF ANTIBACTERIAL AND ANTITOXIC BREAST-MILK IMMUNITY IN RESPONSE TO INGESTION OF THE VACCINES SO VACCINE LA English DT Article C1 INT CTR DIARRHOEL DIS RES,DHAKA,BANGLADESH. UNIV MARYLAND,SCH MED,CTR VACCINE DEV,BALTIMORE,MD 21201. JOHNS HOPKINS UNIV,SCH PUBL HLTH,DIV GEOG MED,BALTIMORE,MD 21218. CTR DIS CONTROL,DIV ENTER INFECT,ATLANTA,GA 30333. GOTHENBURG UNIV,SCH MED,DEPT MED MICROBIOL,S-41124 GOTHENBURG,SWEDEN. OI Harris, Jeffrey/0000-0001-8728-7195 NR 19 TC 25 Z9 25 U1 0 U2 0 PU BUTTERWORTH-HEINEMANN LTD PI OXFORD PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB SN 0264-410X J9 VACCINE JI Vaccine PD OCT PY 1990 VL 8 IS 5 BP 469 EP 472 DI 10.1016/0264-410X(90)90248-K PG 4 WC Immunology; Medicine, Research & Experimental SC Immunology; Research & Experimental Medicine GA EA744 UT WOS:A1990EA74400010 PM 2251873 ER PT J AU SHAFFER, N WAINWRIGHT, RB MIDDAUGH, JP TAUXE, RV AF SHAFFER, N WAINWRIGHT, RB MIDDAUGH, JP TAUXE, RV TI BOTULISM AMONG ALASKA NATIVES - THE ROLE OF CHANGING FOOD PREPARATION AND CONSUMPTION PRACTICES SO WESTERN JOURNAL OF MEDICINE LA English DT Article C1 CTR DIS CONTROL,ARCTIC INVEST LAB,ANCHORAGE,AK. DIV PUBL HLTH,EPIDEMIOL OFF,ANCHORAGE,AK. RP SHAFFER, N (reprint author), CTR DIS CONTROL,ENTER DIS BRANCH C-09,ATLANTA,GA 30333, USA. NR 14 TC 22 Z9 23 U1 0 U2 1 PU CALIFORNIA PHYSICIAN MAGAZINE PI SAN FRANCISCO PA C/O DONNA TAYLOR, EDITOR, PO BOX 7690, SAN FRANCISCO, CA 94102-7690 SN 0093-0415 J9 WESTERN J MED JI West. J. Med. PD OCT PY 1990 VL 153 IS 4 BP 390 EP 393 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA ED755 UT WOS:A1990ED75500002 PM 2244373 ER PT J AU ANDA, RF WILLIAMSON, DF ESCOBEDO, LG MAST, EE GIOVINO, GA REMINGTON, PL AF ANDA, RF WILLIAMSON, DF ESCOBEDO, LG MAST, EE GIOVINO, GA REMINGTON, PL TI DEPRESSION AND THE DYNAMICS OF SMOKING - A NATIONAL PERSPECTIVE SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 WISCONSIN DEPT HLTH & SOCIAL SERV,BUR COMMUNITY HLTH & PREVENT,MADISON,WI. CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV NUTR,ATLANTA,GA 30333. CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,OFF SMOKING & HLTH,ATLANTA,GA 30333. CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,OFF SURVEILLANCE & ANAL,ATLANTA,GA 30333. RI Tanne, David/F-2560-2010 OI Tanne, David/0000-0002-6699-2220 NR 34 TC 675 Z9 683 U1 7 U2 23 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD SEP 26 PY 1990 VL 264 IS 12 BP 1541 EP 1545 DI 10.1001/jama.264.12.1541 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA DZ687 UT WOS:A1990DZ68700023 PM 2395193 ER PT J AU ESCOBEDO, LG ANDA, RF SMITH, PF REMINGTON, PL MAST, EE AF ESCOBEDO, LG ANDA, RF SMITH, PF REMINGTON, PL MAST, EE TI SOCIODEMOGRAPHIC CHARACTERISTICS OF CIGARETTE-SMOKING INITIATION IN THE UNITED-STATES - IMPLICATIONS FOR SMOKING PREVENTION POLICY SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 WISCONSIN DEPT HLTH & SOCIAL SERV,BUREAU COMMUNITY HLTH & PREVENT,MADISON,WI. RP ESCOBEDO, LG (reprint author), CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,OFF SURVEILLANCE & ANAL,ATLANTA,GA 30333, USA. NR 47 TC 154 Z9 154 U1 4 U2 6 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD SEP 26 PY 1990 VL 264 IS 12 BP 1550 EP 1555 DI 10.1001/jama.264.12.1550 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA DZ687 UT WOS:A1990DZ68700025 PM 2395195 ER PT J AU NORDENBERG, D YIP, R BINKIN, NJ AF NORDENBERG, D YIP, R BINKIN, NJ TI THE EFFECT OF CIGARETTE-SMOKING ON HEMOGLOBIN LEVELS AND ANEMIA SCREENING SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 CTR DIS CONTROL,CTR CHRON DIS PREVENT & HLTH PROMOT,DIV NUTR,MAIL STOP A-41,ATLANTA,GA 30333. NR 23 TC 90 Z9 91 U1 0 U2 2 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD SEP 26 PY 1990 VL 264 IS 12 BP 1556 EP 1559 DI 10.1001/jama.264.12.1556 PG 4 WC Medicine, General & Internal SC General & Internal Medicine GA DZ687 UT WOS:A1990DZ68700026 PM 2395196 ER PT J AU BARNHART, ER MAGGIO, VL ALEXANDER, LR TURNER, WE PATTERSON, DG NEEDHAM, LL REILLY, MH GELBAUM, LT AF BARNHART, ER MAGGIO, VL ALEXANDER, LR TURNER, WE PATTERSON, DG NEEDHAM, LL REILLY, MH GELBAUM, LT TI BACITRACIN-ASSOCIATED PEPTIDES AND CONTAMINATED L-TRYPTOPHAN SO LANCET LA English DT Letter C1 VG INSTRUMENTS INC,DANVERS,MA. GEORGIA INST TECHNOL,ATLANTA,GA 30332. RP BARNHART, ER (reprint author), CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,TOXICOL BRANCH,ATLANTA,GA 30333, USA. RI Needham, Larry/E-4930-2011 NR 6 TC 7 Z9 7 U1 0 U2 0 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD SEP 22 PY 1990 VL 336 IS 8717 BP 742 EP 742 DI 10.1016/0140-6736(90)92231-6 PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA DZ624 UT WOS:A1990DZ62400022 PM 1975907 ER PT J AU DECOCK, KM MARAN, M KOUADIO, JC PORTER, A LAFONTAINE, MF GNAORE, E BRETTON, R GEORGE, JR AF DECOCK, KM MARAN, M KOUADIO, JC PORTER, A LAFONTAINE, MF GNAORE, E BRETTON, R GEORGE, JR TI RAPID TEST FOR DISTINGUISHING HIV-1 AND HIV-2 SO LANCET LA English DT Letter C1 CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,ATLANTA,GA 30333. CTR ANTITUBERCULEUX,ABIDJAN,COTE IVOIRE. RP DECOCK, KM (reprint author), PROJECT RETRO CL,01 BP 1712,ABIDJAN,COTE IVOIRE. NR 6 TC 8 Z9 8 U1 0 U2 0 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD SEP 22 PY 1990 VL 336 IS 8717 BP 757 EP 757 DI 10.1016/0140-6736(90)92257-I PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA DZ624 UT WOS:A1990DZ62400058 PM 1975933 ER PT J AU SCHWARCZ, SK ZENILMAN, JM SCHNELL, D KNAPP, JS HOOK, EW THOMPSON, S JUDSON, FN HOLMES, KK AF SCHWARCZ, SK ZENILMAN, JM SCHNELL, D KNAPP, JS HOOK, EW THOMPSON, S JUDSON, FN HOLMES, KK TI NATIONAL SURVEILLANCE OF ANTIMICROBIAL RESISTANCE IN NEISSERIA-GONORRHOEAE SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 CTR DIS CONTROL,CTR INFECT DIS,SEXUALLY TRANSMITTED DIS LAB PROGRAM,ATLANTA,GA 30333. BALTIMORE CITY DEPT HLTH,BALTIMORE,MD. JOHNS HOPKINS UNIV,DEPT MED,BALTIMORE,MD 21218. EMORY UNIV,SCH MED,DEPT MED,ATLANTA,GA 30322. DENVER PUBL HLTH DEPT,DIV DIS CONTROL,DENVER,CO. UNIV COLORADO,DENVER,CO 80202. UNIV WASHINGTON,CTR AIDS & SEXUALLY TRANSMITTED DIS,SEATTLE,WA 98195. UNIV WASHINGTON,DEPT MED,SEATTLE,WA 98195. RP SCHWARCZ, SK (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,TECH INFORMAT SERV,DIV SEXUALLY TRANSMITTED DIS,ATLANTA,GA 30333, USA. NR 28 TC 118 Z9 119 U1 0 U2 2 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD SEP 19 PY 1990 VL 264 IS 11 BP 1413 EP 1417 DI 10.1001/jama.264.11.1413 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA DY428 UT WOS:A1990DY42800023 PM 2144026 ER PT J AU ROLFS, RT NAKASHIMA, AK AF ROLFS, RT NAKASHIMA, AK TI EPIDEMIOLOGY OF PRIMARY AND SECONDARY SYPHILIS IN THE UNITED-STATES, 1981 THROUGH 1989 SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article RP ROLFS, RT (reprint author), CTR DIS CONTROL,CTR PREVENT SERV,ATLANTA,GA 30333, USA. NR 33 TC 157 Z9 159 U1 3 U2 4 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD SEP 19 PY 1990 VL 264 IS 11 BP 1432 EP 1437 DI 10.1001/jama.264.11.1432 PG 6 WC Medicine, General & Internal SC General & Internal Medicine GA DY428 UT WOS:A1990DY42800027 PM 2391740 ER PT J AU HRUBAN, RH SHIU, MH SENIE, RT WOODRUFF, JM AF HRUBAN, RH SHIU, MH SENIE, RT WOODRUFF, JM TI MALIGNANT PERIPHERAL-NERVE SHEATH TUMORS OF THE BUTTOCK AND LOWER-EXTREMITY - A STUDY OF 43 CASES SO CANCER LA English DT Article C1 MEM SLOAN KETTERING CANC CTR,DEPT PATHOL,1275 YORK AVE,NEW YORK,NY 10021. MEM SLOAN KETTERING CANC CTR,DEPT SURG,NEW YORK,NY 10021. CTR DIS CONTROL,DIV REPROD HLTH,ATLANTA,GA 30333. NR 45 TC 179 Z9 188 U1 0 U2 2 PU WILEY-LISS PI NEW YORK PA DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012 SN 0008-543X J9 CANCER JI Cancer PD SEP 15 PY 1990 VL 66 IS 6 BP 1253 EP 1265 DI 10.1002/1097-0142(19900915)66:6<1253::AID-CNCR2820660627>3.0.CO;2-R PG 13 WC Oncology SC Oncology GA EA881 UT WOS:A1990EA88100026 PM 2119249 ER PT J AU MOORE, PS HIERHOLZER, J DEWITT, W GOUAN, K DJORE, D LIPPEVELD, T PLIKAYTIS, B BROOME, CV AF MOORE, PS HIERHOLZER, J DEWITT, W GOUAN, K DJORE, D LIPPEVELD, T PLIKAYTIS, B BROOME, CV TI RESPIRATORY VIRUSES AND MYCOPLASMA AS COFACTORS FOR EPIDEMIC GROUP-A MENINGOCOCCAL MENINGITIS SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Article C1 CTR DIS CONTROL,DIV BACTERIAL DIS,MENINGITIS & SPECIAL PATHOGENS BRANCH,ATLANTA,GA 30333. HOP CENT,NDJAMENA,CHAD. HARVARD UNIV,INST INT DEV,CAMBRIDGE,MA 02138. CTR DIS CONTROL,DIV VIRAL & RICKETTSIAL DIS,RESP & ENTER VIRUSES BRANCH,ATLANTA,GA 30333. RI Moore, Patrick/F-3960-2011 OI Moore, Patrick/0000-0002-8132-858X NR 31 TC 152 Z9 154 U1 0 U2 1 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD SEP 12 PY 1990 VL 264 IS 10 BP 1271 EP 1275 DI 10.1001/jama.264.10.1271 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA DX719 UT WOS:A1990DX71900031 PM 2117679 ER PT J AU JONES, JL WYKOFF, RF HOLLIS, SL LONGSHORE, ST GAMBLE, WB GUNN, RA AF JONES, JL WYKOFF, RF HOLLIS, SL LONGSHORE, ST GAMBLE, WB GUNN, RA TI PARTNER ACCEPTANCE OF HEALTH DEPARTMENT NOTIFICATION OF HIV EXPOSURE, SOUTH-CAROLINA SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Note C1 S CAROLINA DEPT HLTH & ENVIRONM CONTROL,GREENWOOD,SC. CTR DIS CONTROL,DIV FIELD SERV,ATLANTA,GA 30333. RP JONES, JL (reprint author), S CAROLINA DEPT HLTH & ENVIRONM CONTROL,2600 BULL ST,COLUMBIA,SC 29201, USA. NR 10 TC 27 Z9 28 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD SEP 12 PY 1990 VL 264 IS 10 BP 1284 EP 1286 DI 10.1001/jama.264.10.1284 PG 3 WC Medicine, General & Internal SC General & Internal Medicine GA DX719 UT WOS:A1990DX71900034 PM 2388381 ER PT J AU KEUTER, M VANEIJK, A HOOGSTRATE, M RAASVELD, M VANDEREE, M NGWAWE, WA WATKINS, WM WERE, JBO BRANDLINGBENNETT, AD AF KEUTER, M VANEIJK, A HOOGSTRATE, M RAASVELD, M VANDEREE, M NGWAWE, WA WATKINS, WM WERE, JBO BRANDLINGBENNETT, AD TI COMPARISON OF CHLOROQUINE, PYRIMETHAMINE AND SULFADOXINE, AND CHLORPROGUANIL AND DAPSONE AS TREATMENT FOR FALCIPARUM-MALARIA IN PREGNANT AND NONPREGNANT WOMEN, KAKAMEGA DISTRICT, KENYA SO BRITISH MEDICAL JOURNAL LA English DT Article C1 ST MARYS HOSP,MUMIAS,KENYA. FREE UNIV AMSTERDAM,1007 MC AMSTERDAM,NETHERLANDS. UNIV AMSTERDAM,AMSTERDAM,NETHERLANDS. WELLCOME TRUST RES LABS,NAIROBI,KENYA. KENYA GOVT MED RES CTR,CLIN RES CTR,NAIROBI,KENYA. CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,ATLANTA,GA 30333. NR 36 TC 44 Z9 44 U1 0 U2 1 PU BRITISH MED JOURNAL PUBL GROUP PI LONDON PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON, ENGLAND WC1H 9JR SN 0959-8138 J9 BRIT MED J JI Br. Med. J. PD SEP 8 PY 1990 VL 301 IS 6750 BP 466 EP 470 PG 5 WC Medicine, General & Internal SC General & Internal Medicine GA DX630 UT WOS:A1990DX63000016 PM 2207399 ER PT J AU IMTIAZ, R HOPKINS, DR AF IMTIAZ, R HOPKINS, DR TI PERMANENT DISABILITY FROM DRACUNCULIASIS SO LANCET LA English DT Letter C1 CTR DIS CONTROL,CTR INFECT DIS,DIV PARASIT DIS,ATLANTA,GA 30333. RP IMTIAZ, R (reprint author), GLOBAL 2000 INC,CARTER PRESIDENTIAL CTR,ATLANTA,GA 30307, USA. NR 8 TC 9 Z9 16 U1 0 U2 0 PU LANCET LTD PI LONDON PA 42 BEDFORD SQUARE, LONDON, ENGLAND WC1B 3SL SN 0140-6736 J9 LANCET JI Lancet PD SEP 8 PY 1990 VL 336 IS 8715 BP 630 EP 630 DI 10.1016/0140-6736(90)93427-Q PG 1 WC Medicine, General & Internal SC General & Internal Medicine GA DX401 UT WOS:A1990DX40100046 PM 1975399 ER PT J AU TERABE, S MIYASHITA, Y SHIBATA, O BARNHART, ER ALEXANDER, LR PATTERSON, DG KARGER, BL HOSOYA, K TANAKA, N AF TERABE, S MIYASHITA, Y SHIBATA, O BARNHART, ER ALEXANDER, LR PATTERSON, DG KARGER, BL HOSOYA, K TANAKA, N TI SEPARATION OF HIGHLY HYDROPHOBIC COMPOUNDS BY CYCLODEXTRIN-MODIFIED MICELLAR ELECTROKINETIC CHROMATOGRAPHY SO JOURNAL OF CHROMATOGRAPHY LA English DT Article; Proceedings Paper CT 2ND INTERNATIONAL SYMP ON HIGH PERFORMANCE CAPILLARY ELECTROPHORESIS ( HPCE 90 ) CY JAN 29-31, 1990 CL SAN FRANCISCO, CA C1 KYOTO UNIV,FAC ENGN,DEPT IND CHEM,SAKYO KU,KYOTO 606,JAPAN. CTR DIS CONTROL,TOXICOL BRANCH,ATLANTA,GA 30333. NORTHEASTERN UNIV,BARNETT INST,BOSTON,MA 02115. KYOTO INST TECHNOL,DEPT POLYMER SCI & ENGN,SAKYO KU,KYOTO 606,JAPAN. NR 28 TC 262 Z9 261 U1 1 U2 5 PU ELSEVIER SCIENCE BV PI AMSTERDAM PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS SN 0021-9673 J9 J CHROMATOGR PD SEP 7 PY 1990 VL 516 IS 1 BP 23 EP 31 DI 10.1016/S0021-9673(01)90201-8 PG 9 WC Chemistry, Analytical SC Chemistry GA EA118 UT WOS:A1990EA11800004 ER PT J AU SCHWARTZ, B BREIMAN, RF AF SCHWARTZ, B BREIMAN, RF TI PNEUMOCOCCAL IMMUNIZATION - FROM POLICY TO PRACTICE SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION LA English DT Editorial Material RP SCHWARTZ, B (reprint author), CTR DIS CONTROL,CTR INFECT DIS,DIV BACTERIAL DIS,RESP BRANCH,EPIDEMIOL SECT,ATLANTA,GA 30333, USA. NR 15 TC 8 Z9 8 U1 0 U2 0 PU AMER MEDICAL ASSOC PI CHICAGO PA 515 N STATE ST, CHICAGO, IL 60610 SN 0098-7484 J9 JAMA-J AM MED ASSOC JI JAMA-J. Am. Med. Assoc. PD SEP 5 PY 1990 VL 264 IS 9 BP 1154 EP 1155 PG 2 WC Medicine, General & Internal SC General & Internal Medicine GA DW483 UT WOS:A1990DW48300029 PM 2384941 ER PT J AU DECOCK, KM PORTER, A KOUADIO, J MARAN, M GNAORE, E ADJORLOLO, G LAFONTAINE, MF BRETTON, G DAMET, GMG ODEHOURI, K GEORGE, JR HEYWARD, WL AF DECOCK, KM PORTER, A KOUADIO, J MARAN, M GNAORE, E ADJORLOLO, G LAFONTAINE, MF BRETTON, G DAMET, GMG ODEHOURI, K GEORGE, JR HEYWARD, WL TI RAPID AND SPECIFIC DIAGNOSIS OF HIV-1 AND HIV-2 INFECTIONS - AN EVALUATION OF TESTING STRATEGIES SO AIDS LA English DT Article C1 PROJET RETRO CI,ABIDJAN,COTE IVOIRE. COMITE NATL LUTTE CONTRE SIDA,ABIDJAN,COTE IVOIRE. INST PASTEUR COTE IVOIRE,ABIDJAN,COTE IVOIRE. CTR DIS CONTROL,CTR INFECT DIS,DIV HIV AIDS,ATLANTA,GA 30333. CTR ANTITUBERCULEUX,ABIDJAN,COTE IVOIRE. RP DECOCK, KM (reprint author), CTR DIS CONTROL,INT ACT DIV HIV AIDS,1600 CLIFTON RD NE,ATLANTA,GA 30333, USA. NR 6 TC 75 Z9 76 U1 0 U2 0 PU RAPID SCIENCE PUBLISHERS PI LONDON PA 2-6 BOUNDARY ROW, LONDON, ENGLAND SE1 8NH SN 0269-9370 J9 AIDS JI Aids PD SEP PY 1990 VL 4 IS 9 BP 875 EP 878 DI 10.1097/00002030-199009000-00007 PG 4 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA ED630 UT WOS:A1990ED63000007 PM 2252560 ER PT J AU HASSIG, SE KINKELA, N NSA, W KAMENGA, M NDILU, M FRANCIS, H RYDER, RW AF HASSIG, SE KINKELA, N NSA, W KAMENGA, M NDILU, M FRANCIS, H RYDER, RW TI PREVENTION OF PERINATAL HIV TRANSMISSION - ARE THERE ALTERNATIVES TO PREPREGNANCY SEROLOGICAL SCREENING IN KINSHASA, ZAIRE SO AIDS LA English DT Note C1 TULANE UNIV,SCH PUBL HLTH & TROP MED,NEW ORLEANS,LA 70118. CTR DIS CONTROL,ATLANTA,GA 30333. NIH,BETHESDA,MD 20892. NR 16 TC 10 Z9 10 U1 0 U2 0 PU RAPID SCIENCE PUBLISHERS PI LONDON PA 2-6 BOUNDARY ROW, LONDON, ENGLAND SE1 8NH SN 0269-9370 J9 AIDS JI Aids PD SEP PY 1990 VL 4 IS 9 BP 913 EP 916 DI 10.1097/00002030-199009000-00013 PG 4 WC Immunology; Infectious Diseases; Virology SC Immunology; Infectious Diseases; Virology GA ED630 UT WOS:A1990ED63000013 PM 2252564 ER PT J AU LOOKER, AC SEMPOS, CT LIU, K JOHNSON, CL GUNTER, EW AF LOOKER, AC SEMPOS, CT LIU, K JOHNSON, CL GUNTER, EW TI WITHIN-PERSON VARIANCE IN BIOCHEMICAL INDICATORS OF IRON STATUS - EFFECTS ON PREVALENCE ESTIMATES SO AMERICAN JOURNAL OF CLINICAL NUTRITION LA English DT Article C1 NORTHWESTERN UNIV,DEPT COMMUNITY HLTH & PREVENT MED,CHICAGO,IL 60611. CTR ENVIRONM HLTH & INJURY CONTROL,DIV ENVIRONM HLTH LAB SCI,ATLANTA,GA. RP LOOKER, AC (reprint author), NATL CTR HLTH STAT,DIV HLTH EXAMINAT STAT,ROOM 900,6525 BELCREST RD,HYATTSVILLE,MD 20782, USA. NR 25 TC 33 Z9 33 U1 0 U2 0 PU AMER SOC CLIN NUTRITION INC PI BETHESDA PA 9650 ROCKVILLE PIKE SUBSCRIPTIONS, RM L-2310, BETHESDA, MD 20814-3998 SN 0002-9165 J9 AM J CLIN NUTR JI Am. J. Clin. Nutr. PD SEP PY 1990 VL 52 IS 3 BP 541 EP 547 PG 7 WC Nutrition & Dietetics SC Nutrition & Dietetics GA DW373 UT WOS:A1990DW37300025 PM 2393013 ER EF