EMFit                   Fitting multi-component normal mixture models
                        by R package mixtools
alphaBeta               Calculating a significance score of a gene
                        based on the corresponding sgRNAs' p-values of
                        the gene.
calculateGeneLFC        Calculating gene-level log fold ratios
calculateGenePval       Calculating gene level p-values using modified
                        robust rank aggregation (alpha-RRA method) on
                        sgRNAs' p-values
densityPlot             2D density contour plot of gene log2 fold
                        ratios against gene expression levels
makeRhoNull             Generating the null distribution of the
                        significance score of a gene.
mda231                  CRISPR screen data of cell line MDA-MB-231.
medianNormalization     Median normalization of sgRNA counts
normalMM                Performing empirical Bayes modeling on limma
                        results
permuteLimma            Modeling CRISPR data with a permutation test
                        between conditions by R package limma
preparePlotData         Prepare data for density plot and ridge plot
ridgePlot               Density ridgeline plot of gene expression
                        levels for different FDR groups.
runLimma                Modeling CRISPR screen data by R package limma
scatterPlot             Scatter plot of log2 fold ratios against gene
                        expression levels
