R: Bayesian Continual Reassessment Method for Phase I Dose-Escalation Trials

# Bayesian Continual Reassessment Method for Phase I Dose-Escalation Trials

## Documentation for package ‘bcrm’ version 0.5.4

- DESCRIPTION file
- Package NEWS
- Package README

## Help Pages

bcrm-package | Bayesian Continual Reassessment Method for Phase I Dose-Escalation Trials
bcrm | Bayesian Continual Reassessment Method for Phase I Dose-Escalation Trials
find.x | Obtain samples from the maximum tolerated dose (MTD) distribution.
getprior | Samples from the specified prior distribution.
plot.bcrm | Plot the estimated dose-toxicity curve
plot.bcrm.sim | Plot the operating characteristics from the simulated trials
plot.threep3 | Plot the operating characteristics from a standard 3+3 trial
Posterior.BRugs | Returns samples from the posterior distributions of each model parameter using OpenBUGS.
Posterior.exact | Returns posterior mean parameter value and summaries of distributions for probability of DLT at each dose level
Posterior.exact.sim | Returns posterior mean parameter value and summaries of distributions for probability of DLT at each dose level
Posterior.R2WinBUGS | Returns samples from the posterior distributions of each model parameter using WinBUGS
Posterior.rjags | Returns samples from the posterior distributions of each model parameter using JAGS.
print.bcrm | Print information regarding a trial conducted using the Bayesian continuous reassessment method
print.bcrm.sim | Print information regarding a trial conducted using the Bayesian continuous reassessment method
print.threep3 | Print information regarding the operating characteristics of a standard 3+3 design
threep3 | Calculate all possible trial pathways for the standard 3+3 design, together with their probability of occurring