Package: SITH
Type: Package
Title: A Spatial Model of Intra-Tumor Heterogeneity
Version: 1.1.0
Date: 2021-01-03
Author: Phillip B. Nicol
Maintainer: Phillip B. Nicol <philnicol740@gmail.com>
Description: Implements a three-dimensional stochastic model of cancer growth and mutation similar to the one described in Waclaw et al. (2015) <doi:10.1038/nature14971>. Allows for interactive 3D visualizations of the simulated tumor. Provides a comprehensive summary of the spatial distribution of mutants within the tumor. Contains functions which create synthetic sequencing datasets from the generated tumor. 
License: GPL (>= 2)
Depends: R (>= 3.6.0)
Imports: Rcpp (>= 1.0.4), scatterplot3d, stats, graphics, grDevices
Suggests: rgl, igraph, knitr, rmarkdown, testthat
LinkingTo: Rcpp
RoxygenNote: 7.1.1
VignetteBuilder: knitr
Encoding: UTF-8
URL: https://github.com/phillipnicol/SITH
BugReports: https://github.com/phillipnicol/SITH/issues
NeedsCompilation: yes
Packaged: 2021-01-04 18:31:46 UTC; phillipnicol
Repository: CRAN
Date/Publication: 2021-01-05 15:10:02 UTC
Built: R 4.6.0; aarch64-apple-darwin23; 2026-04-25 22:23:37 UTC; unix
Archs: SITH.so.dSYM
