Package: IntegMultiReg
Title: Integrative Bayesian Multiple Regression for Multi-Platform
        Biomarkers
Version: 0.1.0
Authors@R: c(
    person("Sinian", "Zhang", email = "zhan9381@umn.edu",
           role = "aut"),
    person("Jianfeng", "Wang", email = "wan01188@umn.edu",
           role = "aut"),
    person("Thierry", "Chekouo", email = "tchekouo@umn.edu",
           role = c("aut", "cre"),
           comment = c(ORCID = "0000-0002-3594-9182")))
Description: A Bayesian framework that integrates several regression models to
    identify a parsimonious set of biomarkers shared across disparate data
    platforms (for example genomic, transcriptomic and proteomic assays).
    Subjects are partitioned into subgroups defined by their pattern of
    platform availability, so that no subject with partially missing platform
    data is excluded, and information is borrowed across subgroups through a
    Markov random field prior on the variable-selection indicators together
    with non-local (product moment) priors on the regression effects. The
    methodology was introduced for time-to-event outcomes by Chekouo,
    Stingo, Doecke and Do (2017) <doi:10.1111/biom.12587>; this package
    additionally supports continuous (Gaussian) and binary (probit) outcomes.
    Posterior inference is carried out by a Markov chain Monte Carlo sampler
    implemented in C for computational efficiency.
License: GPL (>= 3)
Encoding: UTF-8
LazyData: true
Depends: R (>= 4.0.0)
Imports: graphics, grDevices, stats, utils
Suggests: knitr, rmarkdown, testthat (>= 3.0.0)
SystemRequirements: GSL (>= 2.0)
VignetteBuilder: knitr
Config/testthat/edition: 3
NeedsCompilation: yes
Config/roxygen2/version: 8.0.0
RoxygenNote: 7.3.2
Packaged: 2026-08-05 01:44:33 UTC; tchekouo
Author: Sinian Zhang [aut],
  Jianfeng Wang [aut],
  Thierry Chekouo [aut, cre] (ORCID:
    <https://orcid.org/0000-0002-3594-9182>)
Maintainer: Thierry Chekouo <tchekouo@umn.edu>
Repository: CRAN
Date/Publication: 2026-08-09 08:20:07 UTC
