% Generated by roxygen2: do not edit by hand
% Please edit documentation in R/data.R
\docType{data}
\name{hts_primary_raw}
\alias{hts_primary_raw}
\title{Example single-concentration primary screen (raw signals)}
\format{
A data frame with one row per well and the following columns:
\describe{
\item{plate_id}{Plate identifier, \code{"P01"}, \code{"P02"} or \code{"P03"} (character).}
\item{well}{Well identifier such as \code{"A1"} (character).}
\item{row}{Plate row letter, \code{"A"}-\code{"H"} (character).}
\item{col}{Plate column number, \code{1}-\code{12} (integer).}
\item{well_type}{Well role: \code{"NC"} (negative), \code{"PC"} (positive),
\code{"Blank"} or \code{"compound"} (character).}
\item{compound_id}{Compound identifier such as \code{"CPD001"}, \code{NA} for
control and blank wells (character).}
\item{concentration}{Compound concentration (micromolar), \code{NA} for
controls (numeric).}
\item{signal}{Raw instrument signal (numeric).}
}
}
\usage{
hts_primary_raw
}
\description{
A small, simulated primary high-throughput screen in 96-well plate format
with raw readout signals, used to demonstrate the pre-QC, normalisation,
replicate and primary-hit modules. The layout follows good HTS practice: the
outer ring of wells (row A, row H and columns 1 and 12) is a compound-free
evaporation buffer stored as \code{"Blank"} wells, the two inset columns 2 and 11
carry the controls in a rotationally balanced \emph{diagonal} pattern (positive
controls top-left/bottom-right, negative controls top-right/bottom-left), and
the 48 compounds fill the interior block (rows B-G, columns 3-10). Plates
\code{"P01"} and \code{"P02"} are good replicates (Z-prime around 0.8) while \code{"P03"} is
a failed plate.
}
\details{
The data are simulated (see \code{data-raw/make_datasets.R}) and do not
correspond to any real compound or cell line.
}
\keyword{datasets}
