% Generated by roxygen2: do not edit by hand
% Please edit documentation in R/indo.R
\docType{data}
\name{indo}
\alias{indo}
\title{Rectal Indomethacin for Prevention of Post-ERCP Pancreatitis}
\format{
A data frame with 602 observations on the following 33 variables:
\describe{
\item{\code{id}}{Subject identifier (numeric); leading digit indicates
center. Range 1001--4003.}
\item{\code{site}}{Study site (factor, 4 levels):
\code{1_UM} = University of Michigan,
\code{2_IU} = Indiana University,
\code{3_UK} = University of Kentucky,
\code{4_Case} = Case Western Reserve University.}
\item{\code{age}}{Age in years (numeric), range 19--90.}
\item{\code{risk}}{Risk score for post-ERCP pancreatitis (numeric),
range 1--5.5.}
\item{\code{gender}}{Sex (factor): \code{1_female}, \code{2_male}.}
\item{\code{outcome}}{Primary outcome: post-ERCP pancreatitis
(numeric, 1 = yes, 0 = no).}
\item{\code{sod}}{Sphincter of Oddi dysfunction present (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{pep}}{History of prior post-ERCP pancreatitis (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{recpanc}}{History of recurrent pancreatitis (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{psphinc}}{Pancreatic sphincterotomy performed (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{precut}}{Sphincter pre-cut needed to enter papilla (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{difcan}}{Cannulation of papilla was difficult (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{pneudil}}{Pneumatic dilation of papilla performed (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{amp}}{Ampullectomy performed (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{paninj}}{Contrast injected into pancreas (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{acinar}}{Pancreas appeared to have acinarization on imaging
(factor): \code{0_no}, \code{1_yes}.}
\item{\code{brush}}{Brushings taken from pancreatic duct (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{asa81}}{Aspirin used at 81 mg per day (factor with 3 levels):
\code{0_no}, \code{1_yes}, and a third level retained from the
source coding.}
\item{\code{asa325}}{Aspirin used at 325 mg per day (factor with 3
levels): \code{0_no}, \code{1_yes}, and a third level retained from
the source coding.}
\item{\code{asa}}{Aspirin used at any dose (factor with 3 levels):
\code{0_no}, \code{1_yes}, and a third level retained from the
source coding.}
\item{\code{prophystent}}{Pancreatic duct stent placed per endoscopist
judgment (factor): \code{0_no}, \code{1_yes}.}
\item{\code{therastent}}{Pancreatic duct stent placed to treat narrowing
(factor): \code{0_no}, \code{1_yes}.}
\item{\code{pdstent}}{Pancreatic duct stent placed for any reason
(factor): \code{0_no}, \code{1_yes}.}
\item{\code{sodsom}}{Sphincter of Oddi manometry performed (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{bsphinc}}{Biliary sphincterotomy performed (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{bstent}}{Biliary stent placed to relieve obstruction
(factor): \code{0_no}, \code{1_yes}.}
\item{\code{chole}}{Choledocholithiasis present (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{pbmal}}{Biliary duct or pancreatic malignancy found (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{train}}{Trainee participated in ERCP (factor):
\code{0_no}, \code{1_yes}.}
\item{\code{status}}{Patient status (factor):
\code{0_inpatient}, \code{1_outpatient}.}
\item{\code{type}}{Sphincter of Oddi dysfunction type (factor):
\code{0_no SOD}, \code{1_type 1}, \code{2_type 2}, \code{3_type 3}.}
\item{\code{rx}}{Treatment assignment (numeric, 1 = indomethacin,
0 = placebo).}
\item{\code{bleed}}{Reportable gastrointestinal bleeding (numeric,
coded 1 = no, 2 = yes; \code{NA} when not assessed).}
}
}
\source{
Higgins, P. D. R. \pkg{medicaldata}: Data Package for Medical Datasets.
R package, dataset \code{indo_rct}.
\url{https://CRAN.R-project.org/package=medicaldata}
}
\description{
Patient-level data from a multi-center, randomized, double-blind,
placebo-controlled 2-arm trial (n = 602) of rectal indomethacin (100 mg)
versus placebo to prevent post-ERCP pancreatitis in high-risk patients,
as reported by Elmunzer, Higgins, et al. (2012) in the
\emph{New England Journal of Medicine}.

This dataset was originally collected, cleaned, reformatted, and released
for public teaching and research use by Dr. Peter D. R. Higgins in the
\pkg{medicaldata} R package as \code{indo_rct}. The version shipped here is
redistributed in support of the worked examples in this package. The
variable definitions below follow \pkg{medicaldata}; note that a few
columns are stored as numeric (rather than factor) in this copy. Users who
need the authoritative copy or accompanying documentation should consult
\pkg{medicaldata}.
}
\examples{
data(indo)

}
\references{
Elmunzer BJ, Higgins PDR, Saini SD, et al. A randomized trial of rectal
indomethacin to prevent post-ERCP pancreatitis.
\emph{New England Journal of Medicine} 2012; 366(15):1414--1422.
\doi{10.1056/NEJMoa1111103}
}
