Provides a general framework for clinical trial simulations based on the Clinical Scenario Evaluation (CSE) approach. The package supports a broad class of data models (including clinical trials with continuous, binary, survival-type and count-type endpoints as well as multivariate outcomes that are based on combinations of different endpoints), analysis strategies and commonly used evaluation criteria.
| Version: | 1.0.8 |
| Imports: | doParallel, doRNG, foreach, MASS, mvtnorm, stats, survival, utils |
| Suggests: | flextable, knitr, officer, rmarkdown, pander |
| Published: | 2019-05-08 |
| DOI: | 10.32614/CRAN.package.Mediana |
| Author: | Gautier Paux, Alex Dmitrienko. |
| Maintainer: | Gautier Paux <gautier at paux.fr> |
| BugReports: | https://github.com/gpaux/Mediana/issues |
| License: | GPL-2 |
| URL: | http://gpaux.github.io/Mediana/ |
| NeedsCompilation: | no |
| Materials: | README, NEWS |
| In views: | ClinicalTrials |
| CRAN checks: | Mediana results |
| Reference manual: | Mediana.html , Mediana.pdf |
| Vignettes: |
Adjusted p-values and one-sided simultaneous confidence limits (source) Case studies (source, R code) Mediana: an R package for clinical trial simulations (source) |
| Package source: | Mediana_1.0.8.tar.gz |
| Windows binaries: | r-devel: Mediana_1.0.8.zip, r-release: Mediana_1.0.8.zip, r-oldrel: Mediana_1.0.8.zip |
| macOS binaries: | r-release (arm64): Mediana_1.0.8.tgz, r-oldrel (arm64): Mediana_1.0.8.tgz, r-release (x86_64): Mediana_1.0.8.tgz, r-oldrel (x86_64): Mediana_1.0.8.tgz |
| Old sources: | Mediana archive |
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